Guide to the Human Genome
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Search of human proteins with 4826692

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|4826692 defensin, beta 4 precursor [Homo sapiens]
         (64 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|239743453 PREDICTED: hypothetical protein XP_002342852 [Homo ...   143   3e-35
gi|4826692 defensin, beta 4 precursor [Homo sapiens]                  143   3e-35
gi|8923890 defensin, beta 103A precursor [Homo sapiens]                54   2e-08
gi|125656159 beta-defensin 103B precursor [Homo sapiens]               54   2e-08
gi|4885181 defensin, beta 1 preproprotein [Homo sapiens]               33   0.049
gi|239742274 PREDICTED: hypothetical protein XP_002342470 [Homo ...    32   0.14 
gi|239753810 PREDICTED: similar to beta-defensin 130 [Homo sapiens]    31   0.19 
gi|239748374 PREDICTED: hypothetical protein XP_002346650 [Homo ...    31   0.19 
gi|239742299 PREDICTED: hypothetical protein XP_002342487 [Homo ...    31   0.19 
gi|239744548 PREDICTED: hypothetical protein XP_002343194 [Homo ...    30   0.32 
gi|223972632 tRNA-intron nuclease 2 isoform 1 [Homo sapiens]           30   0.54 
gi|13376882 tRNA-intron nuclease 2 isoform 1 [Homo sapiens]            30   0.54 
gi|223972638 tRNA-intron nuclease 2 isoform 4 [Homo sapiens]           30   0.54 
gi|223972634 tRNA-intron nuclease 2 isoform 2 [Homo sapiens]           30   0.54 
gi|126091070 sperm associated antigen 11B isoform E precursor [H...    29   0.92 
gi|71565154 class III alcohol dehydrogenase, chi subunit [Homo s...    27   3.5  
gi|54112385 four and a half LIM domains 3 [Homo sapiens]               27   3.5  
gi|153792351 ADAM metallopeptidase with thrombospondin type 1 mo...    27   3.5  

>gi|239743453 PREDICTED: hypothetical protein XP_002342852 [Homo
          sapiens]
          Length = 64

 Score =  143 bits (361), Expect = 3e-35
 Identities = 64/64 (100%), Positives = 64/64 (100%)

Query: 1  MRVLYLLFSFLFIFLMPLPGVFGGIGDPVTCLKSGAICHPVFCPRRYKQIGTCGLPGTKC 60
          MRVLYLLFSFLFIFLMPLPGVFGGIGDPVTCLKSGAICHPVFCPRRYKQIGTCGLPGTKC
Sbjct: 1  MRVLYLLFSFLFIFLMPLPGVFGGIGDPVTCLKSGAICHPVFCPRRYKQIGTCGLPGTKC 60

Query: 61 CKKP 64
          CKKP
Sbjct: 61 CKKP 64


>gi|4826692 defensin, beta 4 precursor [Homo sapiens]
          Length = 64

 Score =  143 bits (361), Expect = 3e-35
 Identities = 64/64 (100%), Positives = 64/64 (100%)

Query: 1  MRVLYLLFSFLFIFLMPLPGVFGGIGDPVTCLKSGAICHPVFCPRRYKQIGTCGLPGTKC 60
          MRVLYLLFSFLFIFLMPLPGVFGGIGDPVTCLKSGAICHPVFCPRRYKQIGTCGLPGTKC
Sbjct: 1  MRVLYLLFSFLFIFLMPLPGVFGGIGDPVTCLKSGAICHPVFCPRRYKQIGTCGLPGTKC 60

Query: 61 CKKP 64
          CKKP
Sbjct: 61 CKKP 64


>gi|8923890 defensin, beta 103A precursor [Homo sapiens]
          Length = 67

 Score = 54.3 bits (129), Expect = 2e-08
 Identities = 28/66 (42%), Positives = 40/66 (60%), Gaps = 4/66 (6%)

Query: 1  MRVLYLLFSFLFIFLMPLPGVFGGIGDPVT---CLKSGAICHPVFCPRRYKQIGTCGLPG 57
          MR+ YLLF+ LF+FL+P+PG  GGI + +    C   G  C  + C  + +QIG C   G
Sbjct: 1  MRIHYLLFALLFLFLVPVPG-HGGIINTLQKYYCRVRGGRCAVLSCLPKEEQIGKCSTRG 59

Query: 58 TKCCKK 63
           KCC++
Sbjct: 60 RKCCRR 65


>gi|125656159 beta-defensin 103B precursor [Homo sapiens]
          Length = 67

 Score = 54.3 bits (129), Expect = 2e-08
 Identities = 28/66 (42%), Positives = 40/66 (60%), Gaps = 4/66 (6%)

Query: 1  MRVLYLLFSFLFIFLMPLPGVFGGIGDPVT---CLKSGAICHPVFCPRRYKQIGTCGLPG 57
          MR+ YLLF+ LF+FL+P+PG  GGI + +    C   G  C  + C  + +QIG C   G
Sbjct: 1  MRIHYLLFALLFLFLVPVPG-HGGIINTLQKYYCRVRGGRCAVLSCLPKEEQIGKCSTRG 59

Query: 58 TKCCKK 63
           KCC++
Sbjct: 60 RKCCRR 65


>gi|4885181 defensin, beta 1 preproprotein [Homo sapiens]
          Length = 68

 Score = 33.1 bits (74), Expect = 0.049
 Identities = 24/68 (35%), Positives = 28/68 (41%), Gaps = 6/68 (8%)

Query: 1  MRVLYLLFSFLFIFLMPLPG---VFGGIG---DPVTCLKSGAICHPVFCPRRYKQIGTCG 54
          MR  YLL   L + L  +        G+G   D   C+ SG  C    CP   K  GTC 
Sbjct: 1  MRTSYLLLFTLCLLLSEMASGGNFLTGLGHRSDHYNCVSSGGQCLYSACPIFTKIQGTCY 60

Query: 55 LPGTKCCK 62
              KCCK
Sbjct: 61 RGKAKCCK 68


>gi|239742274 PREDICTED: hypothetical protein XP_002342470 [Homo
          sapiens]
          Length = 87

 Score = 31.6 bits (70), Expect = 0.14
 Identities = 23/63 (36%), Positives = 28/63 (44%), Gaps = 3/63 (4%)

Query: 1  MRVLYLLFSFLFIFLMPLPGVFGGIGDPV-TCLKSGAICHPVFCPRRYKQIGTCGLPGTK 59
          MR+  LL   LF  L+  PG  GG+G     CL    +C    C     QIG C     K
Sbjct: 1  MRLHLLLLILLFSILLS-PGNKGGLGPAEGHCLNLSGVCRRDVCKVVEDQIGACRRK-MK 58

Query: 60 CCK 62
          CC+
Sbjct: 59 CCR 61


>gi|239753810 PREDICTED: similar to beta-defensin 130 [Homo sapiens]
          Length = 128

 Score = 31.2 bits (69), Expect = 0.19
 Identities = 16/53 (30%), Positives = 23/53 (43%), Gaps = 1/53 (1%)

Query: 11  LFIFLMPLPGVFGGIGDPVTCLKSGAICHPVFCPRRYKQIGTCGLPGTKCCKK 63
           LF+ L+P   + G I     C+    +C    C      IG C   G KCC++
Sbjct: 60  LFVTLIPKAKMTGVIPGQKQCIALKGVCRDKLCSTLDDTIGICN-EGKKCCRR 111


>gi|239748374 PREDICTED: hypothetical protein XP_002346650 [Homo
           sapiens]
          Length = 128

 Score = 31.2 bits (69), Expect = 0.19
 Identities = 16/53 (30%), Positives = 23/53 (43%), Gaps = 1/53 (1%)

Query: 11  LFIFLMPLPGVFGGIGDPVTCLKSGAICHPVFCPRRYKQIGTCGLPGTKCCKK 63
           LF+ L+P   + G I     C+    +C    C      IG C   G KCC++
Sbjct: 60  LFVTLIPKAKMTGVIPGQKQCIALKGVCRDKLCSTLDDTIGICN-EGKKCCRR 111


>gi|239742299 PREDICTED: hypothetical protein XP_002342487 [Homo
           sapiens]
          Length = 128

 Score = 31.2 bits (69), Expect = 0.19
 Identities = 16/53 (30%), Positives = 23/53 (43%), Gaps = 1/53 (1%)

Query: 11  LFIFLMPLPGVFGGIGDPVTCLKSGAICHPVFCPRRYKQIGTCGLPGTKCCKK 63
           LF+ L+P   + G I     C+    +C    C      IG C   G KCC++
Sbjct: 60  LFVTLIPKAKMTGVIPGQKQCIALKGVCRDKLCSTLDDTIGICN-EGKKCCRR 111


>gi|239744548 PREDICTED: hypothetical protein XP_002343194 [Homo
           sapiens]
          Length = 192

 Score = 30.4 bits (67), Expect = 0.32
 Identities = 20/60 (33%), Positives = 27/60 (45%), Gaps = 2/60 (3%)

Query: 4   LYLLFSFLFIFLMPLPGVFGGIGDP-VTCLKSGAICHPVFCPRRYKQIGTCGLPGTKCCK 62
           L++L   L +F + L  V G +G   V CL    +C    C     QIG C     KCC+
Sbjct: 66  LHVLLLILLLFSILLSPVRGALGPAEVHCLSLSGVCRRDVCKVVEDQIGAC-RRRMKCCR 124


>gi|223972632 tRNA-intron nuclease 2 isoform 1 [Homo sapiens]
          Length = 465

 Score = 29.6 bits (65), Expect = 0.54
 Identities = 17/48 (35%), Positives = 24/48 (50%), Gaps = 4/48 (8%)

Query: 20  GVFGGIGDP---VTCLKSGAICHPVF-CPRRYKQIGTCGLPGTKCCKK 63
           G  GG+GDP   + CL+ G+ CHP      +  +     LP   CCK+
Sbjct: 178 GKSGGVGDPREPLGCLQEGSGCHPTTESFEKSVREDASPLPHVCCCKQ 225


>gi|13376882 tRNA-intron nuclease 2 isoform 1 [Homo sapiens]
          Length = 465

 Score = 29.6 bits (65), Expect = 0.54
 Identities = 17/48 (35%), Positives = 24/48 (50%), Gaps = 4/48 (8%)

Query: 20  GVFGGIGDP---VTCLKSGAICHPVF-CPRRYKQIGTCGLPGTKCCKK 63
           G  GG+GDP   + CL+ G+ CHP      +  +     LP   CCK+
Sbjct: 178 GKSGGVGDPREPLGCLQEGSGCHPTTESFEKSVREDASPLPHVCCCKQ 225


>gi|223972638 tRNA-intron nuclease 2 isoform 4 [Homo sapiens]
          Length = 402

 Score = 29.6 bits (65), Expect = 0.54
 Identities = 17/48 (35%), Positives = 24/48 (50%), Gaps = 4/48 (8%)

Query: 20  GVFGGIGDP---VTCLKSGAICHPVF-CPRRYKQIGTCGLPGTKCCKK 63
           G  GG+GDP   + CL+ G+ CHP      +  +     LP   CCK+
Sbjct: 178 GKSGGVGDPREPLGCLQEGSGCHPTTESFEKSVREDASPLPHVCCCKQ 225


>gi|223972634 tRNA-intron nuclease 2 isoform 2 [Homo sapiens]
          Length = 439

 Score = 29.6 bits (65), Expect = 0.54
 Identities = 17/48 (35%), Positives = 24/48 (50%), Gaps = 4/48 (8%)

Query: 20  GVFGGIGDP---VTCLKSGAICHPVF-CPRRYKQIGTCGLPGTKCCKK 63
           G  GG+GDP   + CL+ G+ CHP      +  +     LP   CCK+
Sbjct: 178 GKSGGVGDPREPLGCLQEGSGCHPTTESFEKSVREDASPLPHVCCCKQ 225


>gi|126091070 sperm associated antigen 11B isoform E precursor
          [Homo sapiens]
          Length = 80

 Score = 28.9 bits (63), Expect = 0.92
 Identities = 18/59 (30%), Positives = 28/59 (47%), Gaps = 2/59 (3%)

Query: 4  LYLLFSFLFIFLMPLPG-VFGGIGDPVTCLKSGAICHPVFCPRRYKQIGTCGLPGTKCC 61
          ++ LF+ LF  +    G V  GI + +  ++ G IC   FC    K+   C  P  +CC
Sbjct: 3  VFFLFAVLFCLVQTNSGDVPPGIRNTICHMQQG-ICRLFFCHSGEKKRDICSDPWNRCC 60


>gi|71565154 class III alcohol dehydrogenase, chi subunit [Homo
           sapiens]
          Length = 374

 Score = 26.9 bits (58), Expect = 3.5
 Identities = 16/47 (34%), Positives = 23/47 (48%), Gaps = 7/47 (14%)

Query: 20  GVFGGIGDPVTCLKSGAICHPVFCPRRYKQIGTCGL---PGTKCCKK 63
           G+   +G+ VT LK+G    P++ P    Q G C     P T  C+K
Sbjct: 71  GIVESVGEGVTKLKAGDTVIPLYIP----QCGECKFCLNPKTNLCQK 113


>gi|54112385 four and a half LIM domains 3 [Homo sapiens]
          Length = 280

 Score = 26.9 bits (58), Expect = 3.5
 Identities = 11/36 (30%), Positives = 18/36 (50%), Gaps = 3/36 (8%)

Query: 27  DPVTCLKSGAICHPVFCPRRYKQIGTCG---LPGTK 59
           +P TC  S  +C+  +C     Q   CG   +PG++
Sbjct: 78  EPFTCQDSELLCNDCYCSAFSSQCSACGETVMPGSR 113


>gi|153792351 ADAM metallopeptidase with thrombospondin type 1
           motif, 8 preproprotein [Homo sapiens]
          Length = 889

 Score = 26.9 bits (58), Expect = 3.5
 Identities = 13/32 (40%), Positives = 17/32 (53%), Gaps = 1/32 (3%)

Query: 31  CLKSGAICHPVFCPRRYKQIGTCGLPGTKCCK 62
           C+K+G   H V  PR+  + G CG  G  C K
Sbjct: 661 CVKAGCD-HVVDSPRKLDKCGVCGGKGNSCRK 691


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.335    0.155    0.551 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 3,002,163
Number of Sequences: 37866
Number of extensions: 118061
Number of successful extensions: 524
Number of sequences better than 10.0: 18
Number of HSP's better than 10.0 without gapping: 5
Number of HSP's successfully gapped in prelim test: 13
Number of HSP's that attempted gapping in prelim test: 516
Number of HSP's gapped (non-prelim): 18
length of query: 64
length of database: 18,247,518
effective HSP length: 37
effective length of query: 27
effective length of database: 16,846,476
effective search space: 454854852
effective search space used: 454854852
T: 11
A: 40
X1: 15 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 39 (21.5 bits)
S2: 55 (25.8 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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