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Search of human proteins with 48255959
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|48255959 plasma membrane calcium ATPase 4 isoform 4a [Homo
sapiens]
(1170 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|48255959 plasma membrane calcium ATPase 4 isoform 4a [Homo sa... 2318 0.0
gi|48255957 plasma membrane calcium ATPase 4 isoform 4b [Homo sa... 2195 0.0
gi|48255947 plasma membrane calcium ATPase 1 isoform 1a [Homo sa... 1798 0.0
gi|48255945 plasma membrane calcium ATPase 1 isoform 1b [Homo sa... 1776 0.0
gi|48255953 plasma membrane calcium ATPase 3 isoform 3a [Homo sa... 1774 0.0
gi|48255955 plasma membrane calcium ATPase 3 isoform 3b [Homo sa... 1756 0.0
gi|48255951 plasma membrane calcium ATPase 2 isoform 1 [Homo sap... 1714 0.0
gi|48255949 plasma membrane calcium ATPase 2 isoform 2 [Homo sap... 1712 0.0
gi|28373103 ATPase, Ca++ transporting, ubiquitous isoform a [Hom... 300 7e-81
gi|28373115 ATPase, Ca++ transporting, ubiquitous isoform c [Hom... 300 7e-81
gi|28373113 ATPase, Ca++ transporting, ubiquitous isoform f [Hom... 300 7e-81
gi|28373111 ATPase, Ca++ transporting, ubiquitous isoform c [Hom... 300 7e-81
gi|28373109 ATPase, Ca++ transporting, ubiquitous isoform b [Hom... 300 7e-81
gi|28373107 ATPase, Ca++ transporting, ubiquitous isoform d [Hom... 300 7e-81
gi|28373105 ATPase, Ca++ transporting, ubiquitous isoform e [Hom... 300 7e-81
gi|10835220 ATPase, Ca++ transporting, fast twitch 1 isoform b [... 295 2e-79
gi|27886529 ATPase, Ca++ transporting, fast twitch 1 isoform a [... 295 2e-79
gi|24638454 ATPase, Ca++ transporting, slow twitch 2 isoform 1 [... 294 4e-79
gi|4502285 ATPase, Ca++ transporting, slow twitch 2 isoform 2 [H... 291 2e-78
gi|48762691 calcium-transporting ATPase 2C1 isoform 1b [Homo sap... 290 4e-78
gi|48762689 calcium-transporting ATPase 2C1 isoform 1d [Homo sap... 290 4e-78
gi|48762685 calcium-transporting ATPase 2C1 isoform 1a [Homo sap... 290 4e-78
gi|48762687 calcium-transporting ATPase 2C1 isoform 1c [Homo sap... 289 1e-77
gi|209413709 ATPase, Ca++ transporting, slow twitch 2 isoform 3 ... 270 8e-72
gi|83700225 hydrogen/potassium-exchanging ATPase 12A [Homo sapiens] 246 9e-65
gi|118498343 ATPase, Ca++ transporting, type 2C, member 2 [Homo ... 243 8e-64
gi|237681109 Na+/K+ -ATPase alpha 1 subunit isoform c [Homo sapi... 237 4e-62
gi|237681111 Na+/K+ -ATPase alpha 1 subunit isoform d [Homo sapi... 237 4e-62
gi|21361181 Na+/K+ -ATPase alpha 1 subunit isoform a [Homo sapiens] 237 4e-62
gi|153946397 Na+/K+ -ATPase alpha 4 subunit isoform 1 [Homo sapi... 225 2e-58
>gi|48255959 plasma membrane calcium ATPase 4 isoform 4a [Homo
sapiens]
Length = 1170
Score = 2318 bits (6006), Expect = 0.0
Identities = 1170/1170 (100%), Positives = 1170/1170 (100%)
Query: 1 MTNPSDRVLPANSMAESREGDFGCTVMELRKLMELRSRDALTQINVHYGGVQNLCSRLKT 60
MTNPSDRVLPANSMAESREGDFGCTVMELRKLMELRSRDALTQINVHYGGVQNLCSRLKT
Sbjct: 1 MTNPSDRVLPANSMAESREGDFGCTVMELRKLMELRSRDALTQINVHYGGVQNLCSRLKT 60
Query: 61 SPVEGLSGNPADLEKRRQVFGHNVIPPKKPKTFLELVWEALQDVTLIILEIAAIISLVLS 120
SPVEGLSGNPADLEKRRQVFGHNVIPPKKPKTFLELVWEALQDVTLIILEIAAIISLVLS
Sbjct: 61 SPVEGLSGNPADLEKRRQVFGHNVIPPKKPKTFLELVWEALQDVTLIILEIAAIISLVLS 120
Query: 121 FYRPAGEENELCGQVATTPEDENEAQAGWIEGAAILFSVIIVVLVTAFNDWSKEKQFRGL 180
FYRPAGEENELCGQVATTPEDENEAQAGWIEGAAILFSVIIVVLVTAFNDWSKEKQFRGL
Sbjct: 121 FYRPAGEENELCGQVATTPEDENEAQAGWIEGAAILFSVIIVVLVTAFNDWSKEKQFRGL 180
Query: 181 QCRIEQEQKFSIIRNGQLIQLPVAEIVVGDIAQVKYGDLLPADGILIQGNDLKIDESSLT 240
QCRIEQEQKFSIIRNGQLIQLPVAEIVVGDIAQVKYGDLLPADGILIQGNDLKIDESSLT
Sbjct: 181 QCRIEQEQKFSIIRNGQLIQLPVAEIVVGDIAQVKYGDLLPADGILIQGNDLKIDESSLT 240
Query: 241 GESDHVKKSLDKDPMLLSGTHVMEGSGRMVVTAVGVNSQTGIILTLLGVNEDDEGEKKKK 300
GESDHVKKSLDKDPMLLSGTHVMEGSGRMVVTAVGVNSQTGIILTLLGVNEDDEGEKKKK
Sbjct: 241 GESDHVKKSLDKDPMLLSGTHVMEGSGRMVVTAVGVNSQTGIILTLLGVNEDDEGEKKKK 300
Query: 301 GKKQGVPENRNKAKTQDGVALEIQPLNSQEGIDNEEKDKKAVKVPKKEKSVLQGKLTRLA 360
GKKQGVPENRNKAKTQDGVALEIQPLNSQEGIDNEEKDKKAVKVPKKEKSVLQGKLTRLA
Sbjct: 301 GKKQGVPENRNKAKTQDGVALEIQPLNSQEGIDNEEKDKKAVKVPKKEKSVLQGKLTRLA 360
Query: 361 VQIGKAGLLMSALTVFILILYFVIDNFVINRRPWLPECTPIYIQYFVKFFIIGITVLVVA 420
VQIGKAGLLMSALTVFILILYFVIDNFVINRRPWLPECTPIYIQYFVKFFIIGITVLVVA
Sbjct: 361 VQIGKAGLLMSALTVFILILYFVIDNFVINRRPWLPECTPIYIQYFVKFFIIGITVLVVA 420
Query: 421 VPEGLPLAVTISLAYSVKKMMKDNNLVRHLDACETMGNATAICSDKTGTLTMNRMTVVQA 480
VPEGLPLAVTISLAYSVKKMMKDNNLVRHLDACETMGNATAICSDKTGTLTMNRMTVVQA
Sbjct: 421 VPEGLPLAVTISLAYSVKKMMKDNNLVRHLDACETMGNATAICSDKTGTLTMNRMTVVQA 480
Query: 481 YIGGIHYRQIPSPDVFLPKVLDLIVNGISINSAYTSKILPPEKEGGLPRQVGNKTECALL 540
YIGGIHYRQIPSPDVFLPKVLDLIVNGISINSAYTSKILPPEKEGGLPRQVGNKTECALL
Sbjct: 481 YIGGIHYRQIPSPDVFLPKVLDLIVNGISINSAYTSKILPPEKEGGLPRQVGNKTECALL 540
Query: 541 GFVTDLKQDYQAVRNEVPEEKLYKVYTFNSVRKSMSTVIRNPNGGFRMYSKGASEIILRK 600
GFVTDLKQDYQAVRNEVPEEKLYKVYTFNSVRKSMSTVIRNPNGGFRMYSKGASEIILRK
Sbjct: 541 GFVTDLKQDYQAVRNEVPEEKLYKVYTFNSVRKSMSTVIRNPNGGFRMYSKGASEIILRK 600
Query: 601 CNRILDRKGEAVPFKNKDRDDMVRTVIEPMACDGLRTICIAYRDFDDTEPSWDNENEILT 660
CNRILDRKGEAVPFKNKDRDDMVRTVIEPMACDGLRTICIAYRDFDDTEPSWDNENEILT
Sbjct: 601 CNRILDRKGEAVPFKNKDRDDMVRTVIEPMACDGLRTICIAYRDFDDTEPSWDNENEILT 660
Query: 661 ELTCIAVVGIEDPVRPEVPDAIAKCKQAGITVRMVTGDNINTARAIATKCGILTPGDDFL 720
ELTCIAVVGIEDPVRPEVPDAIAKCKQAGITVRMVTGDNINTARAIATKCGILTPGDDFL
Sbjct: 661 ELTCIAVVGIEDPVRPEVPDAIAKCKQAGITVRMVTGDNINTARAIATKCGILTPGDDFL 720
Query: 721 CLEGKEFNRLIRNEKGEVEQEKLDKIWPKLRVLARSSPTDKHTLVKGIIDSTVGEHRQVV 780
CLEGKEFNRLIRNEKGEVEQEKLDKIWPKLRVLARSSPTDKHTLVKGIIDSTVGEHRQVV
Sbjct: 721 CLEGKEFNRLIRNEKGEVEQEKLDKIWPKLRVLARSSPTDKHTLVKGIIDSTVGEHRQVV 780
Query: 781 AVTGDGTNDGPALKKADVGFAMGIAGTDVAKEASDIILTDDNFTSIVKAVMWGRNVYDSI 840
AVTGDGTNDGPALKKADVGFAMGIAGTDVAKEASDIILTDDNFTSIVKAVMWGRNVYDSI
Sbjct: 781 AVTGDGTNDGPALKKADVGFAMGIAGTDVAKEASDIILTDDNFTSIVKAVMWGRNVYDSI 840
Query: 841 SKFLQFQLTVNVVAVIVAFTGACITQDSPLKAVQMLWVNLIMDTFASLALATEPPTESLL 900
SKFLQFQLTVNVVAVIVAFTGACITQDSPLKAVQMLWVNLIMDTFASLALATEPPTESLL
Sbjct: 841 SKFLQFQLTVNVVAVIVAFTGACITQDSPLKAVQMLWVNLIMDTFASLALATEPPTESLL 900
Query: 901 KRRPYGRNKPLISRTMMKNILGHAFYQLIVIFILVFAGEKFFDIDSGRKAPLHSPPSQHY 960
KRRPYGRNKPLISRTMMKNILGHAFYQLIVIFILVFAGEKFFDIDSGRKAPLHSPPSQHY
Sbjct: 901 KRRPYGRNKPLISRTMMKNILGHAFYQLIVIFILVFAGEKFFDIDSGRKAPLHSPPSQHY 960
Query: 961 TIVFNTFVLMQLFNEINSRKIHGEKNVFSGIYRNIIFCSVVLGTFICQIFIVEFGGKPFS 1020
TIVFNTFVLMQLFNEINSRKIHGEKNVFSGIYRNIIFCSVVLGTFICQIFIVEFGGKPFS
Sbjct: 961 TIVFNTFVLMQLFNEINSRKIHGEKNVFSGIYRNIIFCSVVLGTFICQIFIVEFGGKPFS 1020
Query: 1021 CTSLSLSQWLWCLFIGIGELLWGQFISAIPTRSLKFLKEAGHGTTKEEITKDAEGLDEID 1080
CTSLSLSQWLWCLFIGIGELLWGQFISAIPTRSLKFLKEAGHGTTKEEITKDAEGLDEID
Sbjct: 1021 CTSLSLSQWLWCLFIGIGELLWGQFISAIPTRSLKFLKEAGHGTTKEEITKDAEGLDEID 1080
Query: 1081 HAEMELRRGQILWFRGLNRIQTQIDVINTFQTGASFKGVLRRQNMGQHLDVKLVPSSSYV 1140
HAEMELRRGQILWFRGLNRIQTQIDVINTFQTGASFKGVLRRQNMGQHLDVKLVPSSSYV
Sbjct: 1081 HAEMELRRGQILWFRGLNRIQTQIDVINTFQTGASFKGVLRRQNMGQHLDVKLVPSSSYV 1140
Query: 1141 AVAPVKSSPTTSVPAVSSPPMGNQSGQSVP 1170
AVAPVKSSPTTSVPAVSSPPMGNQSGQSVP
Sbjct: 1141 AVAPVKSSPTTSVPAVSSPPMGNQSGQSVP 1170
>gi|48255957 plasma membrane calcium ATPase 4 isoform 4b [Homo
sapiens]
Length = 1205
Score = 2195 bits (5687), Expect = 0.0
Identities = 1106/1112 (99%), Positives = 1108/1112 (99%)
Query: 1 MTNPSDRVLPANSMAESREGDFGCTVMELRKLMELRSRDALTQINVHYGGVQNLCSRLKT 60
MTNPSDRVLPANSMAESREGDFGCTVMELRKLMELRSRDALTQINVHYGGVQNLCSRLKT
Sbjct: 1 MTNPSDRVLPANSMAESREGDFGCTVMELRKLMELRSRDALTQINVHYGGVQNLCSRLKT 60
Query: 61 SPVEGLSGNPADLEKRRQVFGHNVIPPKKPKTFLELVWEALQDVTLIILEIAAIISLVLS 120
SPVEGLSGNPADLEKRRQVFGHNVIPPKKPKTFLELVWEALQDVTLIILEIAAIISLVLS
Sbjct: 61 SPVEGLSGNPADLEKRRQVFGHNVIPPKKPKTFLELVWEALQDVTLIILEIAAIISLVLS 120
Query: 121 FYRPAGEENELCGQVATTPEDENEAQAGWIEGAAILFSVIIVVLVTAFNDWSKEKQFRGL 180
FYRPAGEENELCGQVATTPEDENEAQAGWIEGAAILFSVIIVVLVTAFNDWSKEKQFRGL
Sbjct: 121 FYRPAGEENELCGQVATTPEDENEAQAGWIEGAAILFSVIIVVLVTAFNDWSKEKQFRGL 180
Query: 181 QCRIEQEQKFSIIRNGQLIQLPVAEIVVGDIAQVKYGDLLPADGILIQGNDLKIDESSLT 240
QCRIEQEQKFSIIRNGQLIQLPVAEIVVGDIAQVKYGDLLPADGILIQGNDLKIDESSLT
Sbjct: 181 QCRIEQEQKFSIIRNGQLIQLPVAEIVVGDIAQVKYGDLLPADGILIQGNDLKIDESSLT 240
Query: 241 GESDHVKKSLDKDPMLLSGTHVMEGSGRMVVTAVGVNSQTGIILTLLGVNEDDEGEKKKK 300
GESDHVKKSLDKDPMLLSGTHVMEGSGRMVVTAVGVNSQTGIILTLLGVNEDDEGEKKKK
Sbjct: 241 GESDHVKKSLDKDPMLLSGTHVMEGSGRMVVTAVGVNSQTGIILTLLGVNEDDEGEKKKK 300
Query: 301 GKKQGVPENRNKAKTQDGVALEIQPLNSQEGIDNEEKDKKAVKVPKKEKSVLQGKLTRLA 360
GKKQGVPENRNKAKTQDGVALEIQPLNSQEGIDNEEKDKKAVKVPKKEKSVLQGKLTRLA
Sbjct: 301 GKKQGVPENRNKAKTQDGVALEIQPLNSQEGIDNEEKDKKAVKVPKKEKSVLQGKLTRLA 360
Query: 361 VQIGKAGLLMSALTVFILILYFVIDNFVINRRPWLPECTPIYIQYFVKFFIIGITVLVVA 420
VQIGKAGLLMSALTVFILILYFVIDNFVINRRPWLPECTPIYIQYFVKFFIIGITVLVVA
Sbjct: 361 VQIGKAGLLMSALTVFILILYFVIDNFVINRRPWLPECTPIYIQYFVKFFIIGITVLVVA 420
Query: 421 VPEGLPLAVTISLAYSVKKMMKDNNLVRHLDACETMGNATAICSDKTGTLTMNRMTVVQA 480
VPEGLPLAVTISLAYSVKKMMKDNNLVRHLDACETMGNATAICSDKTGTLTMNRMTVVQA
Sbjct: 421 VPEGLPLAVTISLAYSVKKMMKDNNLVRHLDACETMGNATAICSDKTGTLTMNRMTVVQA 480
Query: 481 YIGGIHYRQIPSPDVFLPKVLDLIVNGISINSAYTSKILPPEKEGGLPRQVGNKTECALL 540
YIGGIHYRQIPSPDVFLPKVLDLIVNGISINSAYTSKILPPEKEGGLPRQVGNKTECALL
Sbjct: 481 YIGGIHYRQIPSPDVFLPKVLDLIVNGISINSAYTSKILPPEKEGGLPRQVGNKTECALL 540
Query: 541 GFVTDLKQDYQAVRNEVPEEKLYKVYTFNSVRKSMSTVIRNPNGGFRMYSKGASEIILRK 600
GFVTDLKQDYQAVRNEVPEEKLYKVYTFNSVRKSMSTVIRNPNGGFRMYSKGASEIILRK
Sbjct: 541 GFVTDLKQDYQAVRNEVPEEKLYKVYTFNSVRKSMSTVIRNPNGGFRMYSKGASEIILRK 600
Query: 601 CNRILDRKGEAVPFKNKDRDDMVRTVIEPMACDGLRTICIAYRDFDDTEPSWDNENEILT 660
CNRILDRKGEAVPFKNKDRDDMVRTVIEPMACDGLRTICIAYRDFDDTEPSWDNENEILT
Sbjct: 601 CNRILDRKGEAVPFKNKDRDDMVRTVIEPMACDGLRTICIAYRDFDDTEPSWDNENEILT 660
Query: 661 ELTCIAVVGIEDPVRPEVPDAIAKCKQAGITVRMVTGDNINTARAIATKCGILTPGDDFL 720
ELTCIAVVGIEDPVRPEVPDAIAKCKQAGITVRMVTGDNINTARAIATKCGILTPGDDFL
Sbjct: 661 ELTCIAVVGIEDPVRPEVPDAIAKCKQAGITVRMVTGDNINTARAIATKCGILTPGDDFL 720
Query: 721 CLEGKEFNRLIRNEKGEVEQEKLDKIWPKLRVLARSSPTDKHTLVKGIIDSTVGEHRQVV 780
CLEGKEFNRLIRNEKGEVEQEKLDKIWPKLRVLARSSPTDKHTLVKGIIDSTVGEHRQVV
Sbjct: 721 CLEGKEFNRLIRNEKGEVEQEKLDKIWPKLRVLARSSPTDKHTLVKGIIDSTVGEHRQVV 780
Query: 781 AVTGDGTNDGPALKKADVGFAMGIAGTDVAKEASDIILTDDNFTSIVKAVMWGRNVYDSI 840
AVTGDGTNDGPALKKADVGFAMGIAGTDVAKEASDIILTDDNFTSIVKAVMWGRNVYDSI
Sbjct: 781 AVTGDGTNDGPALKKADVGFAMGIAGTDVAKEASDIILTDDNFTSIVKAVMWGRNVYDSI 840
Query: 841 SKFLQFQLTVNVVAVIVAFTGACITQDSPLKAVQMLWVNLIMDTFASLALATEPPTESLL 900
SKFLQFQLTVNVVAVIVAFTGACITQDSPLKAVQMLWVNLIMDTFASLALATEPPTESLL
Sbjct: 841 SKFLQFQLTVNVVAVIVAFTGACITQDSPLKAVQMLWVNLIMDTFASLALATEPPTESLL 900
Query: 901 KRRPYGRNKPLISRTMMKNILGHAFYQLIVIFILVFAGEKFFDIDSGRKAPLHSPPSQHY 960
KRRPYGRNKPLISRTMMKNILGHAFYQLIVIFILVFAGEKFFDIDSGRKAPLHSPPSQHY
Sbjct: 901 KRRPYGRNKPLISRTMMKNILGHAFYQLIVIFILVFAGEKFFDIDSGRKAPLHSPPSQHY 960
Query: 961 TIVFNTFVLMQLFNEINSRKIHGEKNVFSGIYRNIIFCSVVLGTFICQIFIVEFGGKPFS 1020
TIVFNTFVLMQLFNEINSRKIHGEKNVFSGIYRNIIFCSVVLGTFICQIFIVEFGGKPFS
Sbjct: 961 TIVFNTFVLMQLFNEINSRKIHGEKNVFSGIYRNIIFCSVVLGTFICQIFIVEFGGKPFS 1020
Query: 1021 CTSLSLSQWLWCLFIGIGELLWGQFISAIPTRSLKFLKEAGHGTTKEEITKDAEGLDEID 1080
CTSLSLSQWLWCLFIGIGELLWGQFISAIPTRSLKFLKEAGHGTTKEEITKDAEGLDEID
Sbjct: 1021 CTSLSLSQWLWCLFIGIGELLWGQFISAIPTRSLKFLKEAGHGTTKEEITKDAEGLDEID 1080
Query: 1081 HAEMELRRGQILWFRGLNRIQTQIDVINTFQT 1112
HAEMELRRGQILWFRGLNRIQTQI V+ F +
Sbjct: 1081 HAEMELRRGQILWFRGLNRIQTQIKVVKAFHS 1112
>gi|48255947 plasma membrane calcium ATPase 1 isoform 1a [Homo
sapiens]
Length = 1176
Score = 1798 bits (4658), Expect = 0.0
Identities = 903/1152 (78%), Positives = 1010/1152 (87%), Gaps = 14/1152 (1%)
Query: 12 NSMAESR-EGDFGCTVMELRKLMELRSRDALTQINVHYGGVQNLCSRLKTSPVEGLSGNP 70
NS+ E+ +GDFG T+ ELR LMELRS DAL +I YG V +C++LKTSP EGLSGNP
Sbjct: 16 NSLKEANHDGDFGITLAELRALMELRSTDALRKIQESYGDVYGICTKLKTSPNEGLSGNP 75
Query: 71 ADLEKRRQVFGHNVIPPKKPKTFLELVWEALQDVTLIILEIAAIISLVLSFYRPAGEENE 130
ADLE+R VFG N IPPKKPKTFL+LVWEALQDVTLIILEIAAI+SL LSFY+P +N
Sbjct: 76 ADLERREAVFGKNFIPPKKPKTFLQLVWEALQDVTLIILEIAAIVSLGLSFYQPPEGDNA 135
Query: 131 LCGQVATTPEDENEAQAGWIEGAAILFSVIIVVLVTAFNDWSKEKQFRGLQCRIEQEQKF 190
LCG+V+ E+E E + GWIEGAAIL SV+ VVLVTAFNDWSKEKQFRGLQ RIEQEQKF
Sbjct: 136 LCGEVSVG-EEEGEGETGWIEGAAILLSVVCVVLVTAFNDWSKEKQFRGLQSRIEQEQKF 194
Query: 191 SIIRNGQLIQLPVAEIVVGDIAQVKYGDLLPADGILIQGNDLKIDESSLTGESDHVKKSL 250
++IR GQ+IQ+PVA+I VGDIAQVKYGDLLPADGILIQGNDLKIDESSLTGESDHVKKSL
Sbjct: 195 TVIRGGQVIQIPVADITVGDIAQVKYGDLLPADGILIQGNDLKIDESSLTGESDHVKKSL 254
Query: 251 DKDPMLLSGTHVMEGSGRMVVTAVGVNSQTGIILTLLGVNED-----DEGEKKKKGKKQ- 304
DKDP+LLSGTHVMEGSGRMVVTAVGVNSQTGII TLLG + DE +K+KK KKQ
Sbjct: 255 DKDPLLLSGTHVMEGSGRMVVTAVGVNSQTGIIFTLLGAGGEEEEKKDEKKKEKKNKKQD 314
Query: 305 GVPENRNKAKTQDGVALEIQPLNSQEGIDNEEKDKKAVKVPKKEKSVLQGKLTRLAVQIG 364
G ENRNKAK QDG A+E+QPL S+EG D +EKDKK +PKKEKSVLQGKLT+LAVQIG
Sbjct: 315 GAIENRNKAKAQDGAAMEMQPLKSEEGGDGDEKDKKKANLPKKEKSVLQGKLTKLAVQIG 374
Query: 365 KAGLLMSALTVFILILYFVIDNFVINRRPWLPECTPIYIQYFVKFFIIGITVLVVAVPEG 424
KAGLLMSA+TV IL+LYFVID F + +RPWL ECTPIYIQYFVKFFIIG+TVLVVAVPEG
Sbjct: 375 KAGLLMSAITVIILVLYFVIDTFWVQKRPWLAECTPIYIQYFVKFFIIGVTVLVVAVPEG 434
Query: 425 LPLAVTISLAYSVKKMMKDNNLVRHLDACETMGNATAICSDKTGTLTMNRMTVVQAYIGG 484
LPLAVTISLAYSVKKMMKDNNLVRHLDACETMGNATAICSDKTGTLTMNRMTVVQAYI
Sbjct: 435 LPLAVTISLAYSVKKMMKDNNLVRHLDACETMGNATAICSDKTGTLTMNRMTVVQAYINE 494
Query: 485 IHYRQIPSPDVFLPKVLDLIVNGISINSAYTSKILPPEKEGGLPRQVGNKTECALLGFVT 544
HY+++P P+ P +L +V GIS+N AYTSKILPPEKEGGLPR VGNKTECALLG +
Sbjct: 495 KHYKKVPEPEAIPPNILSYLVTGISVNCAYTSKILPPEKEGGLPRHVGNKTECALLGLLL 554
Query: 545 DLKQDYQAVRNEVPEEKLYKVYTFNSVRKSMSTVIRNPNGGFRMYSKGASEIILRKCNRI 604
DLK+DYQ VRNE+PEE LYKVYTFNSVRKSMSTV++N +G +R++SKGASEIIL+KC +I
Sbjct: 555 DLKRDYQDVRNEIPEEALYKVYTFNSVRKSMSTVLKNSDGSYRIFSKGASEIILKKCFKI 614
Query: 605 LDRKGEAVPFKNKDRDDMVRTVIEPMACDGLRTICIAYRDFD--DTEPSWDNENEILTEL 662
L GEA F+ +DRDD+V+TVIEPMA +GLRTIC+A+RDF + EP WDNEN+I+T L
Sbjct: 615 LSANGEAKVFRPRDRDDIVKTVIEPMASEGLRTICLAFRDFPAGEPEPEWDNENDIVTGL 674
Query: 663 TCIAVVGIEDPVRPEVPDAIAKCKQAGITVRMVTGDNINTARAIATKCGILTPGDDFLCL 722
TCIAVVGIEDPVRPEVPDAI KC++AGITVRMVTGDNINTARAIATKCGIL PG+DFLCL
Sbjct: 675 TCIAVVGIEDPVRPEVPDAIKKCQRAGITVRMVTGDNINTARAIATKCGILHPGEDFLCL 734
Query: 723 EGKEFNRLIRNEKGEVEQEKLDKIWPKLRVLARSSPTDKHTLVKGIIDSTVGEHRQVVAV 782
EGK+FNR IRNEKGE+EQE++DKIWPKLRVLARSSPTDKHTLVKGIIDSTV + RQVVAV
Sbjct: 735 EGKDFNRRIRNEKGEIEQERIDKIWPKLRVLARSSPTDKHTLVKGIIDSTVSDQRQVVAV 794
Query: 783 TGDGTNDGPALKKADVGFAMGIAGTDVAKEASDIILTDDNFTSIVKAVMWGRNVYDSISK 842
TGDGTNDGPALKKADVGFAMGIAGTDVAKEASDIILTDDNFTSIVKAVMWGRNVYDSISK
Sbjct: 795 TGDGTNDGPALKKADVGFAMGIAGTDVAKEASDIILTDDNFTSIVKAVMWGRNVYDSISK 854
Query: 843 FLQFQLTVNVVAVIVAFTGACITQDSPLKAVQMLWVNLIMDTFASLALATEPPTESLLKR 902
FLQFQLTVNVVAVIVAFTGACITQDSPLKAVQMLWVNLIMDT ASLALATEPPTESLL R
Sbjct: 855 FLQFQLTVNVVAVIVAFTGACITQDSPLKAVQMLWVNLIMDTLASLALATEPPTESLLLR 914
Query: 903 RPYGRNKPLISRTMMKNILGHAFYQLIVIFILVFAGEKFFDIDSGRKAPLHSPPSQHYTI 962
+PYGRNKPLISRTMMKNILGHAFYQL+V+F L+FAGEKFFDIDSGR APLH+PPS+HYTI
Sbjct: 915 KPYGRNKPLISRTMMKNILGHAFYQLVVVFTLLFAGEKFFDIDSGRNAPLHAPPSEHYTI 974
Query: 963 VFNTFVLMQLFNEINSRKIHGEKNVFSGIYRNIIFCSVVLGTFICQIFIVEFGGKPFSCT 1022
VFNTFVLMQLFNEIN+RKIHGE+NVF GI+ N IFC++VLGTF+ QI IV+FGGKPFSC+
Sbjct: 975 VFNTFVLMQLFNEINARKIHGERNVFEGIFNNAIFCTIVLGTFVVQIIIVQFGGKPFSCS 1034
Query: 1023 SLSLSQWLWCLFIGIGELLWGQFISAIPTRSLKFLKEAGHGTTKEEITKD--AEGLDEID 1080
LS+ QWLW +F+G+G LLWGQ IS IPT LKFLKEAGHGT KEEI ++ AE ++EID
Sbjct: 1035 ELSIEQWLWSIFLGMGTLLWGQLISTIPTSRLKFLKEAGHGTQKEEIPEEELAEDVEEID 1094
Query: 1081 HAEMELRRGQILWFRGLNRIQTQIDVINTFQTGASFKGVLRRQN--MGQHLDVKLVPSSS 1138
HAE ELRRGQILWFRGLNRIQTQ+DV+N FQ+G+S +G LRRQ QH DV + + +
Sbjct: 1095 HAERELRRGQILWFRGLNRIQTQMDVVNAFQSGSSIQGALRRQPSIASQHHDVTNISTPT 1154
Query: 1139 YVAVAPVKSSPT 1150
+V + +S T
Sbjct: 1155 HVVFSSSTASTT 1166
>gi|48255945 plasma membrane calcium ATPase 1 isoform 1b [Homo
sapiens]
Length = 1220
Score = 1776 bits (4599), Expect = 0.0
Identities = 900/1184 (76%), Positives = 1015/1184 (85%), Gaps = 35/1184 (2%)
Query: 12 NSMAESR-EGDFGCTVMELRKLMELRSRDALTQINVHYGGVQNLCSRLKTSPVEGLSGNP 70
NS+ E+ +GDFG T+ ELR LMELRS DAL +I YG V +C++LKTSP EGLSGNP
Sbjct: 16 NSLKEANHDGDFGITLAELRALMELRSTDALRKIQESYGDVYGICTKLKTSPNEGLSGNP 75
Query: 71 ADLEKRRQVFGHNVIPPKKPKTFLELVWEALQDVTLIILEIAAIISLVLSFYRPAGEENE 130
ADLE+R VFG N IPPKKPKTFL+LVWEALQDVTLIILEIAAI+SL LSFY+P +N
Sbjct: 76 ADLERREAVFGKNFIPPKKPKTFLQLVWEALQDVTLIILEIAAIVSLGLSFYQPPEGDNA 135
Query: 131 LCGQVATTPEDENEAQAGWIEGAAILFSVIIVVLVTAFNDWSKEKQFRGLQCRIEQEQKF 190
LCG+V+ E+E E + GWIEGAAIL SV+ VVLVTAFNDWSKEKQFRGLQ RIEQEQKF
Sbjct: 136 LCGEVSVG-EEEGEGETGWIEGAAILLSVVCVVLVTAFNDWSKEKQFRGLQSRIEQEQKF 194
Query: 191 SIIRNGQLIQLPVAEIVVGDIAQVKYGDLLPADGILIQGNDLKIDESSLTGESDHVKKSL 250
++IR GQ+IQ+PVA+I VGDIAQVKYGDLLPADGILIQGNDLKIDESSLTGESDHVKKSL
Sbjct: 195 TVIRGGQVIQIPVADITVGDIAQVKYGDLLPADGILIQGNDLKIDESSLTGESDHVKKSL 254
Query: 251 DKDPMLLSGTHVMEGSGRMVVTAVGVNSQTGIILTLLGVNED-----DEGEKKKKGKKQ- 304
DKDP+LLSGTHVMEGSGRMVVTAVGVNSQTGII TLLG + DE +K+KK KKQ
Sbjct: 255 DKDPLLLSGTHVMEGSGRMVVTAVGVNSQTGIIFTLLGAGGEEEEKKDEKKKEKKNKKQD 314
Query: 305 GVPENRNKAKTQDGVALEIQPLNSQEGIDNEEKDKKAVKVPKKEKSVLQGKLTRLAVQIG 364
G ENRNKAK QDG A+E+QPL S+EG D +EKDKK +PKKEKSVLQGKLT+LAVQIG
Sbjct: 315 GAIENRNKAKAQDGAAMEMQPLKSEEGGDGDEKDKKKANLPKKEKSVLQGKLTKLAVQIG 374
Query: 365 KAGLLMSALTVFILILYFVIDNFVINRRPWLPECTPIYIQYFVKFFIIGITVLVVAVPEG 424
KAGLLMSA+TV IL+LYFVID F + +RPWL ECTPIYIQYFVKFFIIG+TVLVVAVPEG
Sbjct: 375 KAGLLMSAITVIILVLYFVIDTFWVQKRPWLAECTPIYIQYFVKFFIIGVTVLVVAVPEG 434
Query: 425 LPLAVTISLAYSVKKMMKDNNLVRHLDACETMGNATAICSDKTGTLTMNRMTVVQAYIGG 484
LPLAVTISLAYSVKKMMKDNNLVRHLDACETMGNATAICSDKTGTLTMNRMTVVQAYI
Sbjct: 435 LPLAVTISLAYSVKKMMKDNNLVRHLDACETMGNATAICSDKTGTLTMNRMTVVQAYINE 494
Query: 485 IHYRQIPSPDVFLPKVLDLIVNGISINSAYTSKILPPEKEGGLPRQVGNKTECALLGFVT 544
HY+++P P+ P +L +V GIS+N AYTSKILPPEKEGGLPR VGNKTECALLG +
Sbjct: 495 KHYKKVPEPEAIPPNILSYLVTGISVNCAYTSKILPPEKEGGLPRHVGNKTECALLGLLL 554
Query: 545 DLKQDYQAVRNEVPEEKLYKVYTFNSVRKSMSTVIRNPNGGFRMYSKGASEIILRKCNRI 604
DLK+DYQ VRNE+PEE LYKVYTFNSVRKSMSTV++N +G +R++SKGASEIIL+KC +I
Sbjct: 555 DLKRDYQDVRNEIPEEALYKVYTFNSVRKSMSTVLKNSDGSYRIFSKGASEIILKKCFKI 614
Query: 605 LDRKGEAVPFKNKDRDDMVRTVIEPMACDGLRTICIAYRDFD--DTEPSWDNENEILTEL 662
L GEA F+ +DRDD+V+TVIEPMA +GLRTIC+A+RDF + EP WDNEN+I+T L
Sbjct: 615 LSANGEAKVFRPRDRDDIVKTVIEPMASEGLRTICLAFRDFPAGEPEPEWDNENDIVTGL 674
Query: 663 TCIAVVGIEDPVRPEVPDAIAKCKQAGITVRMVTGDNINTARAIATKCGILTPGDDFLCL 722
TCIAVVGIEDPVRPEVPDAI KC++AGITVRMVTGDNINTARAIATKCGIL PG+DFLCL
Sbjct: 675 TCIAVVGIEDPVRPEVPDAIKKCQRAGITVRMVTGDNINTARAIATKCGILHPGEDFLCL 734
Query: 723 EGKEFNRLIRNEKGEVEQEKLDKIWPKLRVLARSSPTDKHTLVKGIIDSTVGEHRQVVAV 782
EGK+FNR IRNEKGE+EQE++DKIWPKLRVLARSSPTDKHTLVKGIIDSTV + RQVVAV
Sbjct: 735 EGKDFNRRIRNEKGEIEQERIDKIWPKLRVLARSSPTDKHTLVKGIIDSTVSDQRQVVAV 794
Query: 783 TGDGTNDGPALKKADVGFAMGIAGTDVAKEASDIILTDDNFTSIVKAVMWGRNVYDSISK 842
TGDGTNDGPALKKADVGFAMGIAGTDVAKEASDIILTDDNFTSIVKAVMWGRNVYDSISK
Sbjct: 795 TGDGTNDGPALKKADVGFAMGIAGTDVAKEASDIILTDDNFTSIVKAVMWGRNVYDSISK 854
Query: 843 FLQFQLTVNVVAVIVAFTGACITQDSPLKAVQMLWVNLIMDTFASLALATEPPTESLLKR 902
FLQFQLTVNVVAVIVAFTGACITQDSPLKAVQMLWVNLIMDT ASLALATEPPTESLL R
Sbjct: 855 FLQFQLTVNVVAVIVAFTGACITQDSPLKAVQMLWVNLIMDTLASLALATEPPTESLLLR 914
Query: 903 RPYGRNKPLISRTMMKNILGHAFYQLIVIFILVFAGEKFFDIDSGRKAPLHSPPSQHYTI 962
+PYGRNKPLISRTMMKNILGHAFYQL+V+F L+FAGEKFFDIDSGR APLH+PPS+HYTI
Sbjct: 915 KPYGRNKPLISRTMMKNILGHAFYQLVVVFTLLFAGEKFFDIDSGRNAPLHAPPSEHYTI 974
Query: 963 VFNTFVLMQLFNEINSRKIHGEKNVFSGIYRNIIFCSVVLGTFICQIFIVEFGGKPFSCT 1022
VFNTFVLMQLFNEIN+RKIHGE+NVF GI+ N IFC++VLGTF+ QI IV+FGGKPFSC+
Sbjct: 975 VFNTFVLMQLFNEINARKIHGERNVFEGIFNNAIFCTIVLGTFVVQIIIVQFGGKPFSCS 1034
Query: 1023 SLSLSQWLWCLFIGIGELLWGQFISAIPTRSLKFLKEAGHGTTKEEITKD--AEGLDEID 1080
LS+ QWLW +F+G+G LLWGQ IS IPT LKFLKEAGHGT KEEI ++ AE ++EID
Sbjct: 1035 ELSIEQWLWSIFLGMGTLLWGQLISTIPTSRLKFLKEAGHGTQKEEIPEEELAEDVEEID 1094
Query: 1081 HAEMELRRGQILWFRGLNRIQTQIDVINTFQTGASFKGVLRRQ------NMGQHLDVKLV 1134
HAE ELRRGQILWFRGLNRIQTQI V+N F++ + ++G+ + + N H + ++
Sbjct: 1095 HAERELRRGQILWFRGLNRIQTQIRVVNAFRS-SLYEGLEKPESRSSIHNFMTHPEFRIE 1153
Query: 1135 PSSSYVAV---------APVKSSPTTSVPAVSSPPMGNQSGQSV 1169
S ++ + AP K + S PP N++ +V
Sbjct: 1154 DSEPHIPLIDDTDAEDDAPTKRNS-------SPPPSPNKNNNAV 1190
>gi|48255953 plasma membrane calcium ATPase 3 isoform 3a [Homo
sapiens]
Length = 1173
Score = 1774 bits (4594), Expect = 0.0
Identities = 889/1161 (76%), Positives = 1004/1161 (86%), Gaps = 22/1161 (1%)
Query: 20 GDFGCTVMELRKLMELRSRDALTQINVHYGGVQNLCSRLKTSPVEGLSGNPADLEKRRQV 79
G FGCT+ ELR LMELR +AL +I YG V LC RLKTSP EGL+ N DLEKRRQ+
Sbjct: 25 GGFGCTLAELRTLMELRGAEALQKIEEAYGDVSGLCRRLKTSPTEGLADNTNDLEKRRQI 84
Query: 80 FGHNVIPPKKPKTFLELVWEALQDVTLIILEIAAIISLVLSFYRPAGEENELCGQVATTP 139
+G N IPPK+PKTFL+LVWEALQDVTLIILE+AAI+SL LSFY P GEE+E CG V+
Sbjct: 85 YGQNFIPPKQPKTFLQLVWEALQDVTLIILEVAAIVSLGLSFYAPPGEESEACGNVSGGA 144
Query: 140 EDENEAQAGWIEGAAILFSVIIVVLVTAFNDWSKEKQFRGLQCRIEQEQKFSIIRNGQLI 199
EDE EA+AGWIEGAAIL SVI VVLVTAFNDWSKEKQFRGLQ RIEQEQKF++IRNGQL+
Sbjct: 145 EDEGEAEAGWIEGAAILLSVICVVLVTAFNDWSKEKQFRGLQSRIEQEQKFTVIRNGQLL 204
Query: 200 QLPVAEIVVGDIAQVKYGDLLPADGILIQGNDLKIDESSLTGESDHVKKSLDKDPMLLSG 259
Q+PVA +VVGDIAQVKYGDLLPADG+LIQ NDLKIDESSLTGESDHV+KS DKDPMLLSG
Sbjct: 205 QVPVAALVVGDIAQVKYGDLLPADGVLIQANDLKIDESSLTGESDHVRKSADKDPMLLSG 264
Query: 260 THVMEGSGRMVVTAVGVNSQTGIILTLLGVNEDDEGEKKKKGKKQ--GVPENRNKAKTQD 317
THVMEGSGRMVVTAVGVNSQTGII TLLG ++E +K KKGK+Q + ++ KAK QD
Sbjct: 265 THVMEGSGRMVVTAVGVNSQTGIIFTLLGAGGEEEEKKDKKGKQQDGAMESSQTKAKKQD 324
Query: 318 G-VALEIQPLNSQEGIDNEEKDKKAVKVPKKEKSVLQGKLTRLAVQIGKAGLLMSALTVF 376
G VA+E+QPL S EG + EE++KK PKKEKSVLQGKLT+LAVQIGKAGL+MSA+TV
Sbjct: 325 GAVAMEMQPLKSAEGGEMEEREKKKANAPKKEKSVLQGKLTKLAVQIGKAGLVMSAITVI 384
Query: 377 ILILYFVIDNFVINRRPWLPECTPIYIQYFVKFFIIGITVLVVAVPEGLPLAVTISLAYS 436
IL+LYFVI+ FV+ R WL ECTP+Y+QYFVKFFIIG+TVLVVAVPEGLPLAVTISLAYS
Sbjct: 385 ILVLYFVIETFVVEGRTWLAECTPVYVQYFVKFFIIGVTVLVVAVPEGLPLAVTISLAYS 444
Query: 437 VKKMMKDNNLVRHLDACETMGNATAICSDKTGTLTMNRMTVVQAYIGGIHYRQIPSPDVF 496
VKKMMKDNNLVRHLDACETMGNATAICSDKTGTLT NRMTVVQ+Y+G HY++IP+P
Sbjct: 445 VKKMMKDNNLVRHLDACETMGNATAICSDKTGTLTTNRMTVVQSYLGDTHYKEIPAPSAL 504
Query: 497 LPKVLDLIVNGISINSAYTSKILPPEKEGGLPRQVGNKTECALLGFVTDLKQDYQAVRNE 556
PK+LDL+V+ ISINSAYT+KILPPEKEG LPRQVGNKTECALLGFV DLK+D+Q VR +
Sbjct: 505 TPKILDLLVHAISINSAYTTKILPPEKEGALPRQVGNKTECALLGFVLDLKRDFQPVREQ 564
Query: 557 VPEEKLYKVYTFNSVRKSMSTVIRNPNGGFRMYSKGASEIILRKCNRILDRKGEAVPFKN 616
+PE+KLYKVYTFNSVRKSMSTVIR P+GGFR++SKGASEI+L+KC IL+ GE F+
Sbjct: 565 IPEDKLYKVYTFNSVRKSMSTVIRMPDGGFRLFSKGASEILLKKCTNILNSNGELRGFRP 624
Query: 617 KDRDDMVRTVIEPMACDGLRTICIAYRDFD-DTEPSWDNENEILTELTCIAVVGIEDPVR 675
+DRDDMVR +IEPMACDGLRTICIAYRDF EP WDNENE++ +LTCIAVVGIEDPVR
Sbjct: 625 RDRDDMVRKIIEPMACDGLRTICIAYRDFSAGQEPDWDNENEVVGDLTCIAVVGIEDPVR 684
Query: 676 PEVPDAIAKCKQAGITVRMVTGDNINTARAIATKCGILTPGDDFLCLEGKEFNRLIRNEK 735
PEVP+AI KC++AGITVRMVTGDNINTARAIA KCGI+ PG+DFLCLEGKEFNR IRNEK
Sbjct: 685 PEVPEAIRKCQRAGITVRMVTGDNINTARAIAAKCGIIQPGEDFLCLEGKEFNRRIRNEK 744
Query: 736 GEVEQEKLDKIWPKLRVLARSSPTDKHTLVKGIIDSTVGEHRQVVAVTGDGTNDGPALKK 795
GE+EQE+LDK+WPKLRVLARSSPTDKHTLVKGIIDST GE RQVVAVTGDGTNDGPALKK
Sbjct: 745 GEIEQERLDKVWPKLRVLARSSPTDKHTLVKGIIDSTTGEQRQVVAVTGDGTNDGPALKK 804
Query: 796 ADVGFAMGIAGTDVAKEASDIILTDDNFTSIVKAVMWGRNVYDSISKFLQFQLTVNVVAV 855
ADVGFAMGIAGTDVAKEASDIILTDDNFTSIVKAVMWGRNVYDSISKFLQFQLTVNVVAV
Sbjct: 805 ADVGFAMGIAGTDVAKEASDIILTDDNFTSIVKAVMWGRNVYDSISKFLQFQLTVNVVAV 864
Query: 856 IVAFTGACITQDSPLKAVQMLWVNLIMDTFASLALATEPPTESLLKRRPYGRNKPLISRT 915
IVAFTGACITQDSPLKAVQMLWVNLIMDTFASLALATEPPTESLL R+PYGR+KPLISRT
Sbjct: 865 IVAFTGACITQDSPLKAVQMLWVNLIMDTFASLALATEPPTESLLLRKPYGRDKPLISRT 924
Query: 916 MMKNILGHAFYQLIVIFILVFAGEKFFDIDSGRKAPLHSPPSQHYTIVFNTFVLMQLFNE 975
MMKNILGHA YQL +IF L+F GE FFDIDSGR APLHSPPS+HYTI+FNTFV+MQLFNE
Sbjct: 925 MMKNILGHAVYQLAIIFTLLFVGELFFDIDSGRNAPLHSPPSEHYTIIFNTFVMMQLFNE 984
Query: 976 INSRKIHGEKNVFSGIYRNIIFCSVVLGTFICQIFIVEFGGKPFSCTSLSLSQWLWCLFI 1035
IN+RKIHGE+NVF GI+ N IFC++VLGTF QI IV+FGGKPFSC+ LS QWLWCLF+
Sbjct: 985 INARKIHGERNVFDGIFSNPIFCTIVLGTFGIQIVIVQFGGKPFSCSPLSTEQWLWCLFV 1044
Query: 1036 GIGELLWGQFISAIPTRSLKFLKEAGHGTTKEEITKD--AEGLDEIDHAEMELRRGQILW 1093
G+GEL+WGQ I+ IPT LK LKEAGHG K+E+T + AEG +EIDHAE ELRRGQILW
Sbjct: 1045 GVGELVWGQVIATIPTSQLKCLKEAGHGPGKDEMTDEELAEGEEEIDHAERELRRGQILW 1104
Query: 1094 FRGLNRIQTQIDVINTFQTGASFKGVLRRQN--MGQHLDVKLVPSSSYVAVAPVKSSPTT 1151
FRGLNRIQTQ++V++TF+ S +G +RR++ + Q DV + S+PT
Sbjct: 1105 FRGLNRIQTQMEVVSTFKRSGSVQGAVRRRSSVLSQLHDVTNL------------STPTH 1152
Query: 1152 SVPAVSSP--PMGNQSGQSVP 1170
++ + ++P GN G+SVP
Sbjct: 1153 AILSAANPTSAAGNPGGESVP 1173
>gi|48255955 plasma membrane calcium ATPase 3 isoform 3b [Homo
sapiens]
Length = 1220
Score = 1756 bits (4549), Expect = 0.0
Identities = 872/1099 (79%), Positives = 972/1099 (88%), Gaps = 6/1099 (0%)
Query: 20 GDFGCTVMELRKLMELRSRDALTQINVHYGGVQNLCSRLKTSPVEGLSGNPADLEKRRQV 79
G FGCT+ ELR LMELR +AL +I YG V LC RLKTSP EGL+ N DLEKRRQ+
Sbjct: 25 GGFGCTLAELRTLMELRGAEALQKIEEAYGDVSGLCRRLKTSPTEGLADNTNDLEKRRQI 84
Query: 80 FGHNVIPPKKPKTFLELVWEALQDVTLIILEIAAIISLVLSFYRPAGEENELCGQVATTP 139
+G N IPPK+PKTFL+LVWEALQDVTLIILE+AAI+SL LSFY P GEE+E CG V+
Sbjct: 85 YGQNFIPPKQPKTFLQLVWEALQDVTLIILEVAAIVSLGLSFYAPPGEESEACGNVSGGA 144
Query: 140 EDENEAQAGWIEGAAILFSVIIVVLVTAFNDWSKEKQFRGLQCRIEQEQKFSIIRNGQLI 199
EDE EA+AGWIEGAAIL SVI VVLVTAFNDWSKEKQFRGLQ RIEQEQKF++IRNGQL+
Sbjct: 145 EDEGEAEAGWIEGAAILLSVICVVLVTAFNDWSKEKQFRGLQSRIEQEQKFTVIRNGQLL 204
Query: 200 QLPVAEIVVGDIAQVKYGDLLPADGILIQGNDLKIDESSLTGESDHVKKSLDKDPMLLSG 259
Q+PVA +VVGDIAQVKYGDLLPADG+LIQ NDLKIDESSLTGESDHV+KS DKDPMLLSG
Sbjct: 205 QVPVAALVVGDIAQVKYGDLLPADGVLIQANDLKIDESSLTGESDHVRKSADKDPMLLSG 264
Query: 260 THVMEGSGRMVVTAVGVNSQTGIILTLLGVNEDDEGEKKKKGKKQ--GVPENRNKAKTQD 317
THVMEGSGRMVVTAVGVNSQTGII TLLG ++E +K KKGK+Q + ++ KAK QD
Sbjct: 265 THVMEGSGRMVVTAVGVNSQTGIIFTLLGAGGEEEEKKDKKGKQQDGAMESSQTKAKKQD 324
Query: 318 G-VALEIQPLNSQEGIDNEEKDKKAVKVPKKEKSVLQGKLTRLAVQIGKAGLLMSALTVF 376
G VA+E+QPL S EG + EE++KK PKKEKSVLQGKLT+LAVQIGKAGL+MSA+TV
Sbjct: 325 GAVAMEMQPLKSAEGGEMEEREKKKANAPKKEKSVLQGKLTKLAVQIGKAGLVMSAITVI 384
Query: 377 ILILYFVIDNFVINRRPWLPECTPIYIQYFVKFFIIGITVLVVAVPEGLPLAVTISLAYS 436
IL+LYFVI+ FV+ R WL ECTP+Y+QYFVKFFIIG+TVLVVAVPEGLPLAVTISLAYS
Sbjct: 385 ILVLYFVIETFVVEGRTWLAECTPVYVQYFVKFFIIGVTVLVVAVPEGLPLAVTISLAYS 444
Query: 437 VKKMMKDNNLVRHLDACETMGNATAICSDKTGTLTMNRMTVVQAYIGGIHYRQIPSPDVF 496
VKKMMKDNNLVRHLDACETMGNATAICSDKTGTLT NRMTVVQ+Y+G HY++IP+P
Sbjct: 445 VKKMMKDNNLVRHLDACETMGNATAICSDKTGTLTTNRMTVVQSYLGDTHYKEIPAPSAL 504
Query: 497 LPKVLDLIVNGISINSAYTSKILPPEKEGGLPRQVGNKTECALLGFVTDLKQDYQAVRNE 556
PK+LDL+V+ ISINSAYT+KILPPEKEG LPRQVGNKTECALLGFV DLK+D+Q VR +
Sbjct: 505 TPKILDLLVHAISINSAYTTKILPPEKEGALPRQVGNKTECALLGFVLDLKRDFQPVREQ 564
Query: 557 VPEEKLYKVYTFNSVRKSMSTVIRNPNGGFRMYSKGASEIILRKCNRILDRKGEAVPFKN 616
+PE+KLYKVYTFNSVRKSMSTVIR P+GGFR++SKGASEI+L+KC IL+ GE F+
Sbjct: 565 IPEDKLYKVYTFNSVRKSMSTVIRMPDGGFRLFSKGASEILLKKCTNILNSNGELRGFRP 624
Query: 617 KDRDDMVRTVIEPMACDGLRTICIAYRDFD-DTEPSWDNENEILTELTCIAVVGIEDPVR 675
+DRDDMVR +IEPMACDGLRTICIAYRDF EP WDNENE++ +LTCIAVVGIEDPVR
Sbjct: 625 RDRDDMVRKIIEPMACDGLRTICIAYRDFSAGQEPDWDNENEVVGDLTCIAVVGIEDPVR 684
Query: 676 PEVPDAIAKCKQAGITVRMVTGDNINTARAIATKCGILTPGDDFLCLEGKEFNRLIRNEK 735
PEVP+AI KC++AGITVRMVTGDNINTARAIA KCGI+ PG+DFLCLEGKEFNR IRNEK
Sbjct: 685 PEVPEAIRKCQRAGITVRMVTGDNINTARAIAAKCGIIQPGEDFLCLEGKEFNRRIRNEK 744
Query: 736 GEVEQEKLDKIWPKLRVLARSSPTDKHTLVKGIIDSTVGEHRQVVAVTGDGTNDGPALKK 795
GE+EQE+LDK+WPKLRVLARSSPTDKHTLVKGIIDST GE RQVVAVTGDGTNDGPALKK
Sbjct: 745 GEIEQERLDKVWPKLRVLARSSPTDKHTLVKGIIDSTTGEQRQVVAVTGDGTNDGPALKK 804
Query: 796 ADVGFAMGIAGTDVAKEASDIILTDDNFTSIVKAVMWGRNVYDSISKFLQFQLTVNVVAV 855
ADVGFAMGIAGTDVAKEASDIILTDDNFTSIVKAVMWGRNVYDSISKFLQFQLTVNVVAV
Sbjct: 805 ADVGFAMGIAGTDVAKEASDIILTDDNFTSIVKAVMWGRNVYDSISKFLQFQLTVNVVAV 864
Query: 856 IVAFTGACITQDSPLKAVQMLWVNLIMDTFASLALATEPPTESLLKRRPYGRNKPLISRT 915
IVAFTGACITQDSPLKAVQMLWVNLIMDTFASLALATEPPTESLL R+PYGR+KPLISRT
Sbjct: 865 IVAFTGACITQDSPLKAVQMLWVNLIMDTFASLALATEPPTESLLLRKPYGRDKPLISRT 924
Query: 916 MMKNILGHAFYQLIVIFILVFAGEKFFDIDSGRKAPLHSPPSQHYTIVFNTFVLMQLFNE 975
MMKNILGHA YQL +IF L+F GE FFDIDSGR APLHSPPS+HYTI+FNTFV+MQLFNE
Sbjct: 925 MMKNILGHAVYQLAIIFTLLFVGELFFDIDSGRNAPLHSPPSEHYTIIFNTFVMMQLFNE 984
Query: 976 INSRKIHGEKNVFSGIYRNIIFCSVVLGTFICQIFIVEFGGKPFSCTSLSLSQWLWCLFI 1035
IN+RKIHGE+NVF GI+ N IFC++VLGTF QI IV+FGGKPFSC+ LS QWLWCLF+
Sbjct: 985 INARKIHGERNVFDGIFSNPIFCTIVLGTFGIQIVIVQFGGKPFSCSPLSTEQWLWCLFV 1044
Query: 1036 GIGELLWGQFISAIPTRSLKFLKEAGHGTTKEEITKD--AEGLDEIDHAEMELRRGQILW 1093
G+GEL+WGQ I+ IPT LK LKEAGHG K+E+T + AEG +EIDHAE ELRRGQILW
Sbjct: 1045 GVGELVWGQVIATIPTSQLKCLKEAGHGPGKDEMTDEELAEGEEEIDHAERELRRGQILW 1104
Query: 1094 FRGLNRIQTQIDVINTFQT 1112
FRGLNRIQTQI V+ F++
Sbjct: 1105 FRGLNRIQTQIRVVKAFRS 1123
>gi|48255951 plasma membrane calcium ATPase 2 isoform 1 [Homo sapiens]
Length = 1243
Score = 1714 bits (4440), Expect = 0.0
Identities = 865/1149 (75%), Positives = 971/1149 (84%), Gaps = 40/1149 (3%)
Query: 1 MTNPSDRVLPANSMAESREGDFGCTVMELRKLMELRSRDALTQINVHYGGVQNLCSRLKT 60
MTN SD S G+FGCT+ ELR LMELR +A+ +I YG + +C RLKT
Sbjct: 4 MTN-SDFYSKNQRNESSHGGEFGCTMEELRSLMELRGTEAVVKIKETYGDTEAICRRLKT 62
Query: 61 SPVEGLSGNPADLEKRRQVFGHNVIPPKKPKTFLELVWEALQDVTLIILEIAAIISLVLS 120
SPVEGL G DLEKR+Q+FG N IPPKKPKTFL+LVWEALQDVTLIILEIAAIISL LS
Sbjct: 63 SPVEGLPGTAPDLEKRKQIFGQNFIPPKKPKTFLQLVWEALQDVTLIILEIAAIISLGLS 122
Query: 121 FYRPAGEENELCGQVATTPEDENEAQAGWIEGAAILFSVIIVVLVTAFNDWSKEKQFRGL 180
FY P GE NE C EDE EA+AGWIEGAAIL SVI VVLVTAFNDWSKEKQFRGL
Sbjct: 123 FYHPPGEGNEGCATAQGGAEDEGEAEAGWIEGAAILLSVICVVLVTAFNDWSKEKQFRGL 182
Query: 181 QCRIEQEQKFSIIRNGQLIQLPVAEIVVGDIAQVKYGDLLPADGILIQGNDLKIDESSLT 240
Q RIEQEQKF+++R GQ++Q+PVAEIVVGDIAQVKYGDLLPADG+ IQGNDLKIDESSLT
Sbjct: 183 QSRIEQEQKFTVVRAGQVVQIPVAEIVVGDIAQVKYGDLLPADGLFIQGNDLKIDESSLT 242
Query: 241 GESDHVKKSLDKDPMLLSGTHVMEGSGRMVVTAVGVNSQTGIILTLLGVNEDDEGEKKKK 300
GESD V+KS+DKDPMLLSGTHVMEGSGRM+VTAVGVNSQTGII TLLG ++E +K KK
Sbjct: 243 GESDQVRKSVDKDPMLLSGTHVMEGSGRMLVTAVGVNSQTGIIFTLLGAGGEEEEKKDKK 302
Query: 301 GKKQG---------------------------------VPENRNKAKTQDGVA-LEIQPL 326
G K+G V +++KAK QDG A +E+QPL
Sbjct: 303 GVKKGDGLQLPAADGAAASNAADSANASLVNGKMQDGNVDASQSKAKQQDGAAAMEMQPL 362
Query: 327 NSQEGIDNEEKDKKAVKVPKKEKSVLQGKLTRLAVQIGKAGLLMSALTVFILILYFVIDN 386
S EG D + D+K + KKEKSVLQGKLT+LAVQIGKAGL+MSA+TV IL+LYF +D
Sbjct: 363 KSAEGGDAD--DRKKASMHKKEKSVLQGKLTKLAVQIGKAGLVMSAITVIILVLYFTVDT 420
Query: 387 FVINRRPWLPECTPIYIQYFVKFFIIGITVLVVAVPEGLPLAVTISLAYSVKKMMKDNNL 446
FV+N++PWLPECTP+Y+QYFVKFFIIG+TVLVVAVPEGLPLAVTISLAYSVKKMMKDNNL
Sbjct: 421 FVVNKKPWLPECTPVYVQYFVKFFIIGVTVLVVAVPEGLPLAVTISLAYSVKKMMKDNNL 480
Query: 447 VRHLDACETMGNATAICSDKTGTLTMNRMTVVQAYIGGIHYRQIPSPDVFLPKVLDLIVN 506
VRHLDACETMGNATAICSDKTGTLT NRMTVVQAY+G +HY++IP P K ++L++N
Sbjct: 481 VRHLDACETMGNATAICSDKTGTLTTNRMTVVQAYVGDVHYKEIPDPSSINTKTMELLIN 540
Query: 507 GISINSAYTSKILPPEKEGGLPRQVGNKTECALLGFVTDLKQDYQAVRNEVPEEKLYKVY 566
I+INSAYT+KILPPEKEG LPRQVGNKTEC LLGFV DLKQDY+ VR+++PEEKLYKVY
Sbjct: 541 AIAINSAYTTKILPPEKEGALPRQVGNKTECGLLGFVLDLKQDYEPVRSQMPEEKLYKVY 600
Query: 567 TFNSVRKSMSTVIRNPNGGFRMYSKGASEIILRKCNRILDRKGEAVPFKNKDRDDMVRTV 626
TFNSVRKSMSTVI+ P+ FRMYSKGASEI+L+KC +IL+ GE F+ +DRD+MV+ V
Sbjct: 601 TFNSVRKSMSTVIKLPDESFRMYSKGASEIVLKKCCKILNGAGEPRVFRPRDRDEMVKKV 660
Query: 627 IEPMACDGLRTICIAYRDFDDT-EPSWDNENEILTELTCIAVVGIEDPVRPEVPDAIAKC 685
IEPMACDGLRTIC+AYRDF + EP WDNEN+IL ELTCI VVGIEDPVRPEVP+AI KC
Sbjct: 661 IEPMACDGLRTICVAYRDFPSSPEPDWDNENDILNELTCICVVGIEDPVRPEVPEAIRKC 720
Query: 686 KQAGITVRMVTGDNINTARAIATKCGILTPGDDFLCLEGKEFNRLIRNEKGEVEQEKLDK 745
++AGITVRMVTGDNINTARAIA KCGI+ PG+DFLCLEGKEFNR IRNEKGE+EQE++DK
Sbjct: 721 QRAGITVRMVTGDNINTARAIAIKCGIIHPGEDFLCLEGKEFNRRIRNEKGEIEQERIDK 780
Query: 746 IWPKLRVLARSSPTDKHTLVKGIIDSTVGEHRQVVAVTGDGTNDGPALKKADVGFAMGIA 805
IWPKLRVLARSSPTDKHTLVKGIIDST E RQVVAVTGDGTNDGPALKKADVGFAMGIA
Sbjct: 781 IWPKLRVLARSSPTDKHTLVKGIIDSTHTEQRQVVAVTGDGTNDGPALKKADVGFAMGIA 840
Query: 806 GTDVAKEASDIILTDDNFTSIVKAVMWGRNVYDSISKFLQFQLTVNVVAVIVAFTGACIT 865
GTDVAKEASDIILTDDNF+SIVKAVMWGRNVYDSISKFLQFQLTVNVVAVIVAFTGACIT
Sbjct: 841 GTDVAKEASDIILTDDNFSSIVKAVMWGRNVYDSISKFLQFQLTVNVVAVIVAFTGACIT 900
Query: 866 QDSPLKAVQMLWVNLIMDTFASLALATEPPTESLLKRRPYGRNKPLISRTMMKNILGHAF 925
QDSPLKAVQMLWVNLIMDTFASLALATEPPTE+LL R+PYGRNKPLISRTMMKNILGHA
Sbjct: 901 QDSPLKAVQMLWVNLIMDTFASLALATEPPTETLLLRKPYGRNKPLISRTMMKNILGHAV 960
Query: 926 YQLIVIFILVFAGEKFFDIDSGRKAPLHSPPSQHYTIVFNTFVLMQLFNEINSRKIHGEK 985
YQL +IF L+F GEK F IDSGR APLHSPPS+HYTI+FNTFV+MQLFNEIN+RKIHGE+
Sbjct: 961 YQLALIFTLLFVGEKMFQIDSGRNAPLHSPPSEHYTIIFNTFVMMQLFNEINARKIHGER 1020
Query: 986 NVFSGIYRNIIFCSVVLGTFICQIFIVEFGGKPFSCTSLSLSQWLWCLFIGIGELLWGQF 1045
NVF GI+RN IFC++VLGTF QI IV+FGGKPFSC+ L L QW+WC+FIG+GEL+WGQ
Sbjct: 1021 NVFDGIFRNPIFCTIVLGTFAIQIVIVQFGGKPFSCSPLQLDQWMWCIFIGLGELVWGQV 1080
Query: 1046 ISAIPTRSLKFLKEAGHGTTKEEITKDA--EGLDEIDHAEMELRRGQILWFRGLNRIQTQ 1103
I+ IPT LKFLKEAG T KEEI ++ E ++EIDHAE ELRRGQILWFRGLNRIQTQ
Sbjct: 1081 IATIPTSRLKFLKEAGRLTQKEEIPEEELNEDVEEIDHAERELRRGQILWFRGLNRIQTQ 1140
Query: 1104 IDVINTFQT 1112
I V+ F++
Sbjct: 1141 IRVVKAFRS 1149
>gi|48255949 plasma membrane calcium ATPase 2 isoform 2 [Homo sapiens]
Length = 1198
Score = 1712 bits (4435), Expect = 0.0
Identities = 860/1116 (77%), Positives = 962/1116 (86%), Gaps = 19/1116 (1%)
Query: 1 MTNPSDRVLPANSMAESREGDFGCTVMELRKLMELRSRDALTQINVHYGGVQNLCSRLKT 60
MTN SD S G+FGCT+ ELR LMELR +A+ +I YG + +C RLKT
Sbjct: 4 MTN-SDFYSKNQRNESSHGGEFGCTMEELRSLMELRGTEAVVKIKETYGDTEAICRRLKT 62
Query: 61 SPVEGLSGNPADLEKRRQVFGHNVIPPKKPKTFLELVWEALQDVTLIILEIAAIISLVLS 120
SPVEGL G DLEKR+Q+FG N IPPKKPKTFL+LVWEALQDVTLIILEIAAIISL LS
Sbjct: 63 SPVEGLPGTAPDLEKRKQIFGQNFIPPKKPKTFLQLVWEALQDVTLIILEIAAIISLGLS 122
Query: 121 FYRPAGEENELCGQVATTPEDENEAQAGWIEGAAILFSVIIVVLVTAFNDWSKEKQFRGL 180
FY P GE NE C EDE EA+AGWIEGAAIL SVI VVLVTAFNDWSKEKQFRGL
Sbjct: 123 FYHPPGEGNEGCATAQGGAEDEGEAEAGWIEGAAILLSVICVVLVTAFNDWSKEKQFRGL 182
Query: 181 QCRIEQEQKFSIIRNGQLIQLPVAEIVVGDIAQVKYGDLLPADGILIQGNDLKIDESSLT 240
Q RIEQEQKF+++R GQ++Q+PVAEIVVGDIAQVKYGDLLPADG+ IQGNDLKIDESSLT
Sbjct: 183 QSRIEQEQKFTVVRAGQVVQIPVAEIVVGDIAQVKYGDLLPADGLFIQGNDLKIDESSLT 242
Query: 241 GESDHVKKSLDKDPMLLSGTHVMEGSGRMVVTAVGVNSQTGIILTLLGVNEDDEGEKKKK 300
GESD V+KS+DKDPMLLSGTHVMEGSGRM+VTAVGVNSQTGII TLLG ++E +K KK
Sbjct: 243 GESDQVRKSVDKDPMLLSGTHVMEGSGRMLVTAVGVNSQTGIIFTLLGAGGEEEEKKDKK 302
Query: 301 GKKQGVPENRNKAKTQDGVA-LEIQPLNSQEGIDNEEKDKKAVKVPKKEKSVLQGKLTRL 359
AK QDG A +E+QPL S EG D + D+K + KKEKSVLQGKLT+L
Sbjct: 303 ------------AKQQDGAAAMEMQPLKSAEGGDAD--DRKKASMHKKEKSVLQGKLTKL 348
Query: 360 AVQIGKAGLLMSALTVFILILYFVIDNFVINRRPWLPECTPIYIQYFVKFFIIGITVLVV 419
AVQIGKAGL+MSA+TV IL+LYF +D FV+N++PWLPECTP+Y+QYFVKFFIIG+TVLVV
Sbjct: 349 AVQIGKAGLVMSAITVIILVLYFTVDTFVVNKKPWLPECTPVYVQYFVKFFIIGVTVLVV 408
Query: 420 AVPEGLPLAVTISLAYSVKKMMKDNNLVRHLDACETMGNATAICSDKTGTLTMNRMTVVQ 479
AVPEGLPLAVTISLAYSVKKMMKDNNLVRHLDACETMGNATAICSDKTGTLT NRMTVVQ
Sbjct: 409 AVPEGLPLAVTISLAYSVKKMMKDNNLVRHLDACETMGNATAICSDKTGTLTTNRMTVVQ 468
Query: 480 AYIGGIHYRQIPSPDVFLPKVLDLIVNGISINSAYTSKILPPEKEGGLPRQVGNKTECAL 539
AY+G +HY++IP P K ++L++N I+INSAYT+KILPPEKEG LPRQVGNKTEC L
Sbjct: 469 AYVGDVHYKEIPDPSSINTKTMELLINAIAINSAYTTKILPPEKEGALPRQVGNKTECGL 528
Query: 540 LGFVTDLKQDYQAVRNEVPEEKLYKVYTFNSVRKSMSTVIRNPNGGFRMYSKGASEIILR 599
LGFV DLKQDY+ VR+++PEEKLYKVYTFNSVRKSMSTVI+ P+ FRMYSKGASEI+L+
Sbjct: 529 LGFVLDLKQDYEPVRSQMPEEKLYKVYTFNSVRKSMSTVIKLPDESFRMYSKGASEIVLK 588
Query: 600 KCNRILDRKGEAVPFKNKDRDDMVRTVIEPMACDGLRTICIAYRDFDDT-EPSWDNENEI 658
KC +IL+ GE F+ +DRD+MV+ VIEPMACDGLRTIC+AYRDF + EP WDNEN+I
Sbjct: 589 KCCKILNGAGEPRVFRPRDRDEMVKKVIEPMACDGLRTICVAYRDFPSSPEPDWDNENDI 648
Query: 659 LTELTCIAVVGIEDPVRPEVPDAIAKCKQAGITVRMVTGDNINTARAIATKCGILTPGDD 718
L ELTCI VVGIEDPVRPEVP+AI KC++AGITVRMVTGDNINTARAIA KCGI+ PG+D
Sbjct: 649 LNELTCICVVGIEDPVRPEVPEAIRKCQRAGITVRMVTGDNINTARAIAIKCGIIHPGED 708
Query: 719 FLCLEGKEFNRLIRNEKGEVEQEKLDKIWPKLRVLARSSPTDKHTLVKGIIDSTVGEHRQ 778
FLCLEGKEFNR IRNEKGE+EQE++DKIWPKLRVLARSSPTDKHTLVKGIIDST E RQ
Sbjct: 709 FLCLEGKEFNRRIRNEKGEIEQERIDKIWPKLRVLARSSPTDKHTLVKGIIDSTHTEQRQ 768
Query: 779 VVAVTGDGTNDGPALKKADVGFAMGIAGTDVAKEASDIILTDDNFTSIVKAVMWGRNVYD 838
VVAVTGDGTNDGPALKKADVGFAMGIAGTDVAKEASDIILTDDNF+SIVKAVMWGRNVYD
Sbjct: 769 VVAVTGDGTNDGPALKKADVGFAMGIAGTDVAKEASDIILTDDNFSSIVKAVMWGRNVYD 828
Query: 839 SISKFLQFQLTVNVVAVIVAFTGACITQDSPLKAVQMLWVNLIMDTFASLALATEPPTES 898
SISKFLQFQLTVNVVAVIVAFTGACITQDSPLKAVQMLWVNLIMDTFASLALATEPPTE+
Sbjct: 829 SISKFLQFQLTVNVVAVIVAFTGACITQDSPLKAVQMLWVNLIMDTFASLALATEPPTET 888
Query: 899 LLKRRPYGRNKPLISRTMMKNILGHAFYQLIVIFILVFAGEKFFDIDSGRKAPLHSPPSQ 958
LL R+PYGRNKPLISRTMMKNILGHA YQL +IF L+F GEK F IDSGR APLHSPPS+
Sbjct: 889 LLLRKPYGRNKPLISRTMMKNILGHAVYQLALIFTLLFVGEKMFQIDSGRNAPLHSPPSE 948
Query: 959 HYTIVFNTFVLMQLFNEINSRKIHGEKNVFSGIYRNIIFCSVVLGTFICQIFIVEFGGKP 1018
HYTI+FNTFV+MQLFNEIN+RKIHGE+NVF GI+RN IFC++VLGTF QI IV+FGGKP
Sbjct: 949 HYTIIFNTFVMMQLFNEINARKIHGERNVFDGIFRNPIFCTIVLGTFAIQIVIVQFGGKP 1008
Query: 1019 FSCTSLSLSQWLWCLFIGIGELLWGQFISAIPTRSLKFLKEAGHGTTKEEITKDA--EGL 1076
FSC+ L L QW+WC+FIG+GEL+WGQ I+ IPT LKFLKEAG T KEEI ++ E +
Sbjct: 1009 FSCSPLQLDQWMWCIFIGLGELVWGQVIATIPTSRLKFLKEAGRLTQKEEIPEEELNEDV 1068
Query: 1077 DEIDHAEMELRRGQILWFRGLNRIQTQIDVINTFQT 1112
+EIDHAE ELRRGQILWFRGLNRIQTQI V+ F++
Sbjct: 1069 EEIDHAERELRRGQILWFRGLNRIQTQIRVVKAFRS 1104
>gi|28373103 ATPase, Ca++ transporting, ubiquitous isoform a [Homo
sapiens]
Length = 999
Score = 300 bits (767), Expect = 7e-81
Identities = 266/931 (28%), Positives = 431/931 (46%), Gaps = 175/931 (18%)
Query: 69 NPADLEKRRQVFGHNVIPPKKPKTFLELVWEALQDVTLIILEIAAIISLVLSFYRPAGEE 128
+PA + R+ +G N +P ++ K+ ELV E +D+ + IL +AA++S VL+++
Sbjct: 25 SPAQVTGARERYGPNELPSEEGKSLWELVLEQFEDLLVRILLLAALVSFVLAWF------ 78
Query: 129 NELCGQVATTPEDENEAQAGWIEGAAILFSVIIVVLVTAFNDWSKEKQFRGLQCRIEQEQ 188
E+ E ++E I+ ++ +V + + + E L+ E E
Sbjct: 79 -----------EEGEETTTAFVEPLVIMLILVANAIVGVWQERNAESAIEALK---EYEP 124
Query: 189 KFS-IIRNGQ--LIQLPVAEIVVGDIAQVKYGDLLPADGILIQ--GNDLKIDESSLTGES 243
+ +IR+ + + ++ +IV GDI +V GD +PAD LI+ L++D+S LTGES
Sbjct: 125 EMGKVIRSDRKGVQRIRARDIVPGDIVEVAVGDKVPADLRLIEIKSTTLRVDQSILTGES 184
Query: 244 DHVKK-----------SLDKDPMLLSGTHVMEGSGRMVVTAVGVNSQTGIILTLLGVNED 292
V K + DK ML SGT++ G AVGV TG+ T LG
Sbjct: 185 VSVTKHTEAIPDPRAVNQDKKNMLFSGTNITSGK------AVGVAVATGLH-TELG---- 233
Query: 293 DEGEKKKKGKKQGVPENRNKAKTQDGVALEIQPLNSQEGIDNEEKDKKAVKVPKKEKSVL 352
K + + + E++ L
Sbjct: 234 --------------------------------------------KIRSQMAAVEPERTPL 249
Query: 353 QGKLTRLAVQIGKAGLLMSALTVFILILYFVIDNFVINRRPWLPECTPIYIQYFVKFFII 412
Q KL Q+ A + + + V+++ + D P +++ V +F I
Sbjct: 250 QRKLDEFGRQLSHA-ISVICVAVWVINIGHFAD----------PAHGGSWLRGAVYYFKI 298
Query: 413 GITVLVVAVPEGLPLAVTISLAYSVKKMMKDNNLVRHLDACETMGNATAICSDKTGTLTM 472
+ + V A+PEGLP +T LA ++M + N +VR L + ET+G + ICSDKTGTLT
Sbjct: 299 AVALAVAAIPEGLPAVITTCLALGTRRMARKNAIVRSLPSVETLGCTSVICSDKTGTLTT 358
Query: 473 NRMTVVQAYIGG--------IHYRQIPSPDVFLPK-------------VLDLIVNGISIN 511
N+M+V + ++ +H I S + P+ D +V +I
Sbjct: 359 NQMSVCRMFVVAEADAGSCLLHEFTI-SGTTYTPEGEVRQGDQPVRCGQFDGLVELATIC 417
Query: 512 SAYTSKILPPEKEGGLPRQVGNKTECALLGFVTDLK---QDYQAVR--------NEVPEE 560
+ L + G+ +VG TE AL V + D QA+ N V ++
Sbjct: 418 ALCNDSALDYNEAKGVYEKVGEATETALTCLVEKMNVFDTDLQALSRVERAGACNTVIKQ 477
Query: 561 KLYKVYT--FNSVRKSMSTVIR----NPNG-GFRMYSKGASEIILRKCNRILDRKGE-AV 612
+ K +T F+ RKSMS +P G G +M+ KGA E ++ +C+ + R G
Sbjct: 478 LMRKEFTLEFSRDRKSMSVYCTPTRPHPTGQGSKMFVKGAPESVIERCSSV--RVGSRTA 535
Query: 613 PFKNKDRDDMVRTVIE-PMACDGLRTICIAYRDFDDTEPSWDNEN-----EILTELTCIA 666
P R+ ++ + + D LR + +A RD + + ++ + T+LT +
Sbjct: 536 PLTPTSREQILAKIRDWGSGSDTLRCLALATRDAPPRKEDMELDDCSKFVQYETDLTFVG 595
Query: 667 VVGIEDPVRPEVPDAIAKCKQAGITVRMVTGDNINTARAIATKCGILTPGDDFL--CLEG 724
VG+ DP RPEV I +C QAGI V M+TGDN TA AI + GI +D G
Sbjct: 596 CVGMLDPPRPEVAACITRCYQAGIRVVMITGDNKGTAVAICRRLGIFGDTEDVAGKAYTG 655
Query: 725 KEFNRLIRNEKGEVEQEKLDKIWPKLRVLARSSPTDKHTLVKGIIDSTVGEHRQVVAVTG 784
+EF+ ++ E+ + R AR P K +V+ + ++ A+TG
Sbjct: 656 REFD--------DLSPEQQRQACRTARCFARVEPAHKSRIVENL-----QSFNEITAMTG 702
Query: 785 DGTNDGPALKKADVGFAMGIAGTDVAKEASDIILTDDNFTSIVKAVMWGRNVYDSISKFL 844
DG ND PALKKA++G AMG +GT VAK A++++L+DDNF SIV AV GR +Y ++ +F+
Sbjct: 703 DGVNDAPALKKAEIGIAMG-SGTAVAKSAAEMVLSDDNFASIVAAVEEGRAIYSNMKQFI 761
Query: 845 QFQLTVNVVAVIVAFTGACITQDSPLKAVQMLWVNLIMDTFASLALATEPPTESLLKRRP 904
++ ++ NV V+ F A + L VQ+LWVNL+ D + AL PP ++++ P
Sbjct: 762 RYLISSNVGEVVCIFLTAILGLPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMEKLP 821
Query: 905 YGRNKPLISRTMMKNILGHAFYQLIVIFILV 935
+ LIS G F++ + I + V
Sbjct: 822 RSPREALIS--------GWLFFRYLAIGVYV 844
>gi|28373115 ATPase, Ca++ transporting, ubiquitous isoform c [Homo
sapiens]
Length = 1029
Score = 300 bits (767), Expect = 7e-81
Identities = 266/931 (28%), Positives = 431/931 (46%), Gaps = 175/931 (18%)
Query: 69 NPADLEKRRQVFGHNVIPPKKPKTFLELVWEALQDVTLIILEIAAIISLVLSFYRPAGEE 128
+PA + R+ +G N +P ++ K+ ELV E +D+ + IL +AA++S VL+++
Sbjct: 25 SPAQVTGARERYGPNELPSEEGKSLWELVLEQFEDLLVRILLLAALVSFVLAWF------ 78
Query: 129 NELCGQVATTPEDENEAQAGWIEGAAILFSVIIVVLVTAFNDWSKEKQFRGLQCRIEQEQ 188
E+ E ++E I+ ++ +V + + + E L+ E E
Sbjct: 79 -----------EEGEETTTAFVEPLVIMLILVANAIVGVWQERNAESAIEALK---EYEP 124
Query: 189 KFS-IIRNGQ--LIQLPVAEIVVGDIAQVKYGDLLPADGILIQ--GNDLKIDESSLTGES 243
+ +IR+ + + ++ +IV GDI +V GD +PAD LI+ L++D+S LTGES
Sbjct: 125 EMGKVIRSDRKGVQRIRARDIVPGDIVEVAVGDKVPADLRLIEIKSTTLRVDQSILTGES 184
Query: 244 DHVKK-----------SLDKDPMLLSGTHVMEGSGRMVVTAVGVNSQTGIILTLLGVNED 292
V K + DK ML SGT++ G AVGV TG+ T LG
Sbjct: 185 VSVTKHTEAIPDPRAVNQDKKNMLFSGTNITSGK------AVGVAVATGLH-TELG---- 233
Query: 293 DEGEKKKKGKKQGVPENRNKAKTQDGVALEIQPLNSQEGIDNEEKDKKAVKVPKKEKSVL 352
K + + + E++ L
Sbjct: 234 --------------------------------------------KIRSQMAAVEPERTPL 249
Query: 353 QGKLTRLAVQIGKAGLLMSALTVFILILYFVIDNFVINRRPWLPECTPIYIQYFVKFFII 412
Q KL Q+ A + + + V+++ + D P +++ V +F I
Sbjct: 250 QRKLDEFGRQLSHA-ISVICVAVWVINIGHFAD----------PAHGGSWLRGAVYYFKI 298
Query: 413 GITVLVVAVPEGLPLAVTISLAYSVKKMMKDNNLVRHLDACETMGNATAICSDKTGTLTM 472
+ + V A+PEGLP +T LA ++M + N +VR L + ET+G + ICSDKTGTLT
Sbjct: 299 AVALAVAAIPEGLPAVITTCLALGTRRMARKNAIVRSLPSVETLGCTSVICSDKTGTLTT 358
Query: 473 NRMTVVQAYIGG--------IHYRQIPSPDVFLPK-------------VLDLIVNGISIN 511
N+M+V + ++ +H I S + P+ D +V +I
Sbjct: 359 NQMSVCRMFVVAEADAGSCLLHEFTI-SGTTYTPEGEVRQGDQPVRCGQFDGLVELATIC 417
Query: 512 SAYTSKILPPEKEGGLPRQVGNKTECALLGFVTDLK---QDYQAVR--------NEVPEE 560
+ L + G+ +VG TE AL V + D QA+ N V ++
Sbjct: 418 ALCNDSALDYNEAKGVYEKVGEATETALTCLVEKMNVFDTDLQALSRVERAGACNTVIKQ 477
Query: 561 KLYKVYT--FNSVRKSMSTVIR----NPNG-GFRMYSKGASEIILRKCNRILDRKGE-AV 612
+ K +T F+ RKSMS +P G G +M+ KGA E ++ +C+ + R G
Sbjct: 478 LMRKEFTLEFSRDRKSMSVYCTPTRPHPTGQGSKMFVKGAPESVIERCSSV--RVGSRTA 535
Query: 613 PFKNKDRDDMVRTVIE-PMACDGLRTICIAYRDFDDTEPSWDNEN-----EILTELTCIA 666
P R+ ++ + + D LR + +A RD + + ++ + T+LT +
Sbjct: 536 PLTPTSREQILAKIRDWGSGSDTLRCLALATRDAPPRKEDMELDDCSKFVQYETDLTFVG 595
Query: 667 VVGIEDPVRPEVPDAIAKCKQAGITVRMVTGDNINTARAIATKCGILTPGDDFL--CLEG 724
VG+ DP RPEV I +C QAGI V M+TGDN TA AI + GI +D G
Sbjct: 596 CVGMLDPPRPEVAACITRCYQAGIRVVMITGDNKGTAVAICRRLGIFGDTEDVAGKAYTG 655
Query: 725 KEFNRLIRNEKGEVEQEKLDKIWPKLRVLARSSPTDKHTLVKGIIDSTVGEHRQVVAVTG 784
+EF+ ++ E+ + R AR P K +V+ + ++ A+TG
Sbjct: 656 REFD--------DLSPEQQRQACRTARCFARVEPAHKSRIVENL-----QSFNEITAMTG 702
Query: 785 DGTNDGPALKKADVGFAMGIAGTDVAKEASDIILTDDNFTSIVKAVMWGRNVYDSISKFL 844
DG ND PALKKA++G AMG +GT VAK A++++L+DDNF SIV AV GR +Y ++ +F+
Sbjct: 703 DGVNDAPALKKAEIGIAMG-SGTAVAKSAAEMVLSDDNFASIVAAVEEGRAIYSNMKQFI 761
Query: 845 QFQLTVNVVAVIVAFTGACITQDSPLKAVQMLWVNLIMDTFASLALATEPPTESLLKRRP 904
++ ++ NV V+ F A + L VQ+LWVNL+ D + AL PP ++++ P
Sbjct: 762 RYLISSNVGEVVCIFLTAILGLPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMEKLP 821
Query: 905 YGRNKPLISRTMMKNILGHAFYQLIVIFILV 935
+ LIS G F++ + I + V
Sbjct: 822 RSPREALIS--------GWLFFRYLAIGVYV 844
>gi|28373113 ATPase, Ca++ transporting, ubiquitous isoform f [Homo
sapiens]
Length = 998
Score = 300 bits (767), Expect = 7e-81
Identities = 266/931 (28%), Positives = 431/931 (46%), Gaps = 175/931 (18%)
Query: 69 NPADLEKRRQVFGHNVIPPKKPKTFLELVWEALQDVTLIILEIAAIISLVLSFYRPAGEE 128
+PA + R+ +G N +P ++ K+ ELV E +D+ + IL +AA++S VL+++
Sbjct: 25 SPAQVTGARERYGPNELPSEEGKSLWELVLEQFEDLLVRILLLAALVSFVLAWF------ 78
Query: 129 NELCGQVATTPEDENEAQAGWIEGAAILFSVIIVVLVTAFNDWSKEKQFRGLQCRIEQEQ 188
E+ E ++E I+ ++ +V + + + E L+ E E
Sbjct: 79 -----------EEGEETTTAFVEPLVIMLILVANAIVGVWQERNAESAIEALK---EYEP 124
Query: 189 KFS-IIRNGQ--LIQLPVAEIVVGDIAQVKYGDLLPADGILIQ--GNDLKIDESSLTGES 243
+ +IR+ + + ++ +IV GDI +V GD +PAD LI+ L++D+S LTGES
Sbjct: 125 EMGKVIRSDRKGVQRIRARDIVPGDIVEVAVGDKVPADLRLIEIKSTTLRVDQSILTGES 184
Query: 244 DHVKK-----------SLDKDPMLLSGTHVMEGSGRMVVTAVGVNSQTGIILTLLGVNED 292
V K + DK ML SGT++ G AVGV TG+ T LG
Sbjct: 185 VSVTKHTEAIPDPRAVNQDKKNMLFSGTNITSGK------AVGVAVATGLH-TELG---- 233
Query: 293 DEGEKKKKGKKQGVPENRNKAKTQDGVALEIQPLNSQEGIDNEEKDKKAVKVPKKEKSVL 352
K + + + E++ L
Sbjct: 234 --------------------------------------------KIRSQMAAVEPERTPL 249
Query: 353 QGKLTRLAVQIGKAGLLMSALTVFILILYFVIDNFVINRRPWLPECTPIYIQYFVKFFII 412
Q KL Q+ A + + + V+++ + D P +++ V +F I
Sbjct: 250 QRKLDEFGRQLSHA-ISVICVAVWVINIGHFAD----------PAHGGSWLRGAVYYFKI 298
Query: 413 GITVLVVAVPEGLPLAVTISLAYSVKKMMKDNNLVRHLDACETMGNATAICSDKTGTLTM 472
+ + V A+PEGLP +T LA ++M + N +VR L + ET+G + ICSDKTGTLT
Sbjct: 299 AVALAVAAIPEGLPAVITTCLALGTRRMARKNAIVRSLPSVETLGCTSVICSDKTGTLTT 358
Query: 473 NRMTVVQAYIGG--------IHYRQIPSPDVFLPK-------------VLDLIVNGISIN 511
N+M+V + ++ +H I S + P+ D +V +I
Sbjct: 359 NQMSVCRMFVVAEADAGSCLLHEFTI-SGTTYTPEGEVRQGDQPVRCGQFDGLVELATIC 417
Query: 512 SAYTSKILPPEKEGGLPRQVGNKTECALLGFVTDLK---QDYQAVR--------NEVPEE 560
+ L + G+ +VG TE AL V + D QA+ N V ++
Sbjct: 418 ALCNDSALDYNEAKGVYEKVGEATETALTCLVEKMNVFDTDLQALSRVERAGACNTVIKQ 477
Query: 561 KLYKVYT--FNSVRKSMSTVIR----NPNG-GFRMYSKGASEIILRKCNRILDRKGE-AV 612
+ K +T F+ RKSMS +P G G +M+ KGA E ++ +C+ + R G
Sbjct: 478 LMRKEFTLEFSRDRKSMSVYCTPTRPHPTGQGSKMFVKGAPESVIERCSSV--RVGSRTA 535
Query: 613 PFKNKDRDDMVRTVIE-PMACDGLRTICIAYRDFDDTEPSWDNEN-----EILTELTCIA 666
P R+ ++ + + D LR + +A RD + + ++ + T+LT +
Sbjct: 536 PLTPTSREQILAKIRDWGSGSDTLRCLALATRDAPPRKEDMELDDCSKFVQYETDLTFVG 595
Query: 667 VVGIEDPVRPEVPDAIAKCKQAGITVRMVTGDNINTARAIATKCGILTPGDDFL--CLEG 724
VG+ DP RPEV I +C QAGI V M+TGDN TA AI + GI +D G
Sbjct: 596 CVGMLDPPRPEVAACITRCYQAGIRVVMITGDNKGTAVAICRRLGIFGDTEDVAGKAYTG 655
Query: 725 KEFNRLIRNEKGEVEQEKLDKIWPKLRVLARSSPTDKHTLVKGIIDSTVGEHRQVVAVTG 784
+EF+ ++ E+ + R AR P K +V+ + ++ A+TG
Sbjct: 656 REFD--------DLSPEQQRQACRTARCFARVEPAHKSRIVENL-----QSFNEITAMTG 702
Query: 785 DGTNDGPALKKADVGFAMGIAGTDVAKEASDIILTDDNFTSIVKAVMWGRNVYDSISKFL 844
DG ND PALKKA++G AMG +GT VAK A++++L+DDNF SIV AV GR +Y ++ +F+
Sbjct: 703 DGVNDAPALKKAEIGIAMG-SGTAVAKSAAEMVLSDDNFASIVAAVEEGRAIYSNMKQFI 761
Query: 845 QFQLTVNVVAVIVAFTGACITQDSPLKAVQMLWVNLIMDTFASLALATEPPTESLLKRRP 904
++ ++ NV V+ F A + L VQ+LWVNL+ D + AL PP ++++ P
Sbjct: 762 RYLISSNVGEVVCIFLTAILGLPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMEKLP 821
Query: 905 YGRNKPLISRTMMKNILGHAFYQLIVIFILV 935
+ LIS G F++ + I + V
Sbjct: 822 RSPREALIS--------GWLFFRYLAIGVYV 844
>gi|28373111 ATPase, Ca++ transporting, ubiquitous isoform c [Homo
sapiens]
Length = 1029
Score = 300 bits (767), Expect = 7e-81
Identities = 266/931 (28%), Positives = 431/931 (46%), Gaps = 175/931 (18%)
Query: 69 NPADLEKRRQVFGHNVIPPKKPKTFLELVWEALQDVTLIILEIAAIISLVLSFYRPAGEE 128
+PA + R+ +G N +P ++ K+ ELV E +D+ + IL +AA++S VL+++
Sbjct: 25 SPAQVTGARERYGPNELPSEEGKSLWELVLEQFEDLLVRILLLAALVSFVLAWF------ 78
Query: 129 NELCGQVATTPEDENEAQAGWIEGAAILFSVIIVVLVTAFNDWSKEKQFRGLQCRIEQEQ 188
E+ E ++E I+ ++ +V + + + E L+ E E
Sbjct: 79 -----------EEGEETTTAFVEPLVIMLILVANAIVGVWQERNAESAIEALK---EYEP 124
Query: 189 KFS-IIRNGQ--LIQLPVAEIVVGDIAQVKYGDLLPADGILIQ--GNDLKIDESSLTGES 243
+ +IR+ + + ++ +IV GDI +V GD +PAD LI+ L++D+S LTGES
Sbjct: 125 EMGKVIRSDRKGVQRIRARDIVPGDIVEVAVGDKVPADLRLIEIKSTTLRVDQSILTGES 184
Query: 244 DHVKK-----------SLDKDPMLLSGTHVMEGSGRMVVTAVGVNSQTGIILTLLGVNED 292
V K + DK ML SGT++ G AVGV TG+ T LG
Sbjct: 185 VSVTKHTEAIPDPRAVNQDKKNMLFSGTNITSGK------AVGVAVATGLH-TELG---- 233
Query: 293 DEGEKKKKGKKQGVPENRNKAKTQDGVALEIQPLNSQEGIDNEEKDKKAVKVPKKEKSVL 352
K + + + E++ L
Sbjct: 234 --------------------------------------------KIRSQMAAVEPERTPL 249
Query: 353 QGKLTRLAVQIGKAGLLMSALTVFILILYFVIDNFVINRRPWLPECTPIYIQYFVKFFII 412
Q KL Q+ A + + + V+++ + D P +++ V +F I
Sbjct: 250 QRKLDEFGRQLSHA-ISVICVAVWVINIGHFAD----------PAHGGSWLRGAVYYFKI 298
Query: 413 GITVLVVAVPEGLPLAVTISLAYSVKKMMKDNNLVRHLDACETMGNATAICSDKTGTLTM 472
+ + V A+PEGLP +T LA ++M + N +VR L + ET+G + ICSDKTGTLT
Sbjct: 299 AVALAVAAIPEGLPAVITTCLALGTRRMARKNAIVRSLPSVETLGCTSVICSDKTGTLTT 358
Query: 473 NRMTVVQAYIGG--------IHYRQIPSPDVFLPK-------------VLDLIVNGISIN 511
N+M+V + ++ +H I S + P+ D +V +I
Sbjct: 359 NQMSVCRMFVVAEADAGSCLLHEFTI-SGTTYTPEGEVRQGDQPVRCGQFDGLVELATIC 417
Query: 512 SAYTSKILPPEKEGGLPRQVGNKTECALLGFVTDLK---QDYQAVR--------NEVPEE 560
+ L + G+ +VG TE AL V + D QA+ N V ++
Sbjct: 418 ALCNDSALDYNEAKGVYEKVGEATETALTCLVEKMNVFDTDLQALSRVERAGACNTVIKQ 477
Query: 561 KLYKVYT--FNSVRKSMSTVIR----NPNG-GFRMYSKGASEIILRKCNRILDRKGE-AV 612
+ K +T F+ RKSMS +P G G +M+ KGA E ++ +C+ + R G
Sbjct: 478 LMRKEFTLEFSRDRKSMSVYCTPTRPHPTGQGSKMFVKGAPESVIERCSSV--RVGSRTA 535
Query: 613 PFKNKDRDDMVRTVIE-PMACDGLRTICIAYRDFDDTEPSWDNEN-----EILTELTCIA 666
P R+ ++ + + D LR + +A RD + + ++ + T+LT +
Sbjct: 536 PLTPTSREQILAKIRDWGSGSDTLRCLALATRDAPPRKEDMELDDCSKFVQYETDLTFVG 595
Query: 667 VVGIEDPVRPEVPDAIAKCKQAGITVRMVTGDNINTARAIATKCGILTPGDDFL--CLEG 724
VG+ DP RPEV I +C QAGI V M+TGDN TA AI + GI +D G
Sbjct: 596 CVGMLDPPRPEVAACITRCYQAGIRVVMITGDNKGTAVAICRRLGIFGDTEDVAGKAYTG 655
Query: 725 KEFNRLIRNEKGEVEQEKLDKIWPKLRVLARSSPTDKHTLVKGIIDSTVGEHRQVVAVTG 784
+EF+ ++ E+ + R AR P K +V+ + ++ A+TG
Sbjct: 656 REFD--------DLSPEQQRQACRTARCFARVEPAHKSRIVENL-----QSFNEITAMTG 702
Query: 785 DGTNDGPALKKADVGFAMGIAGTDVAKEASDIILTDDNFTSIVKAVMWGRNVYDSISKFL 844
DG ND PALKKA++G AMG +GT VAK A++++L+DDNF SIV AV GR +Y ++ +F+
Sbjct: 703 DGVNDAPALKKAEIGIAMG-SGTAVAKSAAEMVLSDDNFASIVAAVEEGRAIYSNMKQFI 761
Query: 845 QFQLTVNVVAVIVAFTGACITQDSPLKAVQMLWVNLIMDTFASLALATEPPTESLLKRRP 904
++ ++ NV V+ F A + L VQ+LWVNL+ D + AL PP ++++ P
Sbjct: 762 RYLISSNVGEVVCIFLTAILGLPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMEKLP 821
Query: 905 YGRNKPLISRTMMKNILGHAFYQLIVIFILV 935
+ LIS G F++ + I + V
Sbjct: 822 RSPREALIS--------GWLFFRYLAIGVYV 844
>gi|28373109 ATPase, Ca++ transporting, ubiquitous isoform b [Homo
sapiens]
Length = 1043
Score = 300 bits (767), Expect = 7e-81
Identities = 266/931 (28%), Positives = 431/931 (46%), Gaps = 175/931 (18%)
Query: 69 NPADLEKRRQVFGHNVIPPKKPKTFLELVWEALQDVTLIILEIAAIISLVLSFYRPAGEE 128
+PA + R+ +G N +P ++ K+ ELV E +D+ + IL +AA++S VL+++
Sbjct: 25 SPAQVTGARERYGPNELPSEEGKSLWELVLEQFEDLLVRILLLAALVSFVLAWF------ 78
Query: 129 NELCGQVATTPEDENEAQAGWIEGAAILFSVIIVVLVTAFNDWSKEKQFRGLQCRIEQEQ 188
E+ E ++E I+ ++ +V + + + E L+ E E
Sbjct: 79 -----------EEGEETTTAFVEPLVIMLILVANAIVGVWQERNAESAIEALK---EYEP 124
Query: 189 KFS-IIRNGQ--LIQLPVAEIVVGDIAQVKYGDLLPADGILIQ--GNDLKIDESSLTGES 243
+ +IR+ + + ++ +IV GDI +V GD +PAD LI+ L++D+S LTGES
Sbjct: 125 EMGKVIRSDRKGVQRIRARDIVPGDIVEVAVGDKVPADLRLIEIKSTTLRVDQSILTGES 184
Query: 244 DHVKK-----------SLDKDPMLLSGTHVMEGSGRMVVTAVGVNSQTGIILTLLGVNED 292
V K + DK ML SGT++ G AVGV TG+ T LG
Sbjct: 185 VSVTKHTEAIPDPRAVNQDKKNMLFSGTNITSGK------AVGVAVATGLH-TELG---- 233
Query: 293 DEGEKKKKGKKQGVPENRNKAKTQDGVALEIQPLNSQEGIDNEEKDKKAVKVPKKEKSVL 352
K + + + E++ L
Sbjct: 234 --------------------------------------------KIRSQMAAVEPERTPL 249
Query: 353 QGKLTRLAVQIGKAGLLMSALTVFILILYFVIDNFVINRRPWLPECTPIYIQYFVKFFII 412
Q KL Q+ A + + + V+++ + D P +++ V +F I
Sbjct: 250 QRKLDEFGRQLSHA-ISVICVAVWVINIGHFAD----------PAHGGSWLRGAVYYFKI 298
Query: 413 GITVLVVAVPEGLPLAVTISLAYSVKKMMKDNNLVRHLDACETMGNATAICSDKTGTLTM 472
+ + V A+PEGLP +T LA ++M + N +VR L + ET+G + ICSDKTGTLT
Sbjct: 299 AVALAVAAIPEGLPAVITTCLALGTRRMARKNAIVRSLPSVETLGCTSVICSDKTGTLTT 358
Query: 473 NRMTVVQAYIGG--------IHYRQIPSPDVFLPK-------------VLDLIVNGISIN 511
N+M+V + ++ +H I S + P+ D +V +I
Sbjct: 359 NQMSVCRMFVVAEADAGSCLLHEFTI-SGTTYTPEGEVRQGDQPVRCGQFDGLVELATIC 417
Query: 512 SAYTSKILPPEKEGGLPRQVGNKTECALLGFVTDLK---QDYQAVR--------NEVPEE 560
+ L + G+ +VG TE AL V + D QA+ N V ++
Sbjct: 418 ALCNDSALDYNEAKGVYEKVGEATETALTCLVEKMNVFDTDLQALSRVERAGACNTVIKQ 477
Query: 561 KLYKVYT--FNSVRKSMSTVIR----NPNG-GFRMYSKGASEIILRKCNRILDRKGE-AV 612
+ K +T F+ RKSMS +P G G +M+ KGA E ++ +C+ + R G
Sbjct: 478 LMRKEFTLEFSRDRKSMSVYCTPTRPHPTGQGSKMFVKGAPESVIERCSSV--RVGSRTA 535
Query: 613 PFKNKDRDDMVRTVIE-PMACDGLRTICIAYRDFDDTEPSWDNEN-----EILTELTCIA 666
P R+ ++ + + D LR + +A RD + + ++ + T+LT +
Sbjct: 536 PLTPTSREQILAKIRDWGSGSDTLRCLALATRDAPPRKEDMELDDCSKFVQYETDLTFVG 595
Query: 667 VVGIEDPVRPEVPDAIAKCKQAGITVRMVTGDNINTARAIATKCGILTPGDDFL--CLEG 724
VG+ DP RPEV I +C QAGI V M+TGDN TA AI + GI +D G
Sbjct: 596 CVGMLDPPRPEVAACITRCYQAGIRVVMITGDNKGTAVAICRRLGIFGDTEDVAGKAYTG 655
Query: 725 KEFNRLIRNEKGEVEQEKLDKIWPKLRVLARSSPTDKHTLVKGIIDSTVGEHRQVVAVTG 784
+EF+ ++ E+ + R AR P K +V+ + ++ A+TG
Sbjct: 656 REFD--------DLSPEQQRQACRTARCFARVEPAHKSRIVENL-----QSFNEITAMTG 702
Query: 785 DGTNDGPALKKADVGFAMGIAGTDVAKEASDIILTDDNFTSIVKAVMWGRNVYDSISKFL 844
DG ND PALKKA++G AMG +GT VAK A++++L+DDNF SIV AV GR +Y ++ +F+
Sbjct: 703 DGVNDAPALKKAEIGIAMG-SGTAVAKSAAEMVLSDDNFASIVAAVEEGRAIYSNMKQFI 761
Query: 845 QFQLTVNVVAVIVAFTGACITQDSPLKAVQMLWVNLIMDTFASLALATEPPTESLLKRRP 904
++ ++ NV V+ F A + L VQ+LWVNL+ D + AL PP ++++ P
Sbjct: 762 RYLISSNVGEVVCIFLTAILGLPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMEKLP 821
Query: 905 YGRNKPLISRTMMKNILGHAFYQLIVIFILV 935
+ LIS G F++ + I + V
Sbjct: 822 RSPREALIS--------GWLFFRYLAIGVYV 844
>gi|28373107 ATPase, Ca++ transporting, ubiquitous isoform d [Homo
sapiens]
Length = 1044
Score = 300 bits (767), Expect = 7e-81
Identities = 266/931 (28%), Positives = 431/931 (46%), Gaps = 175/931 (18%)
Query: 69 NPADLEKRRQVFGHNVIPPKKPKTFLELVWEALQDVTLIILEIAAIISLVLSFYRPAGEE 128
+PA + R+ +G N +P ++ K+ ELV E +D+ + IL +AA++S VL+++
Sbjct: 25 SPAQVTGARERYGPNELPSEEGKSLWELVLEQFEDLLVRILLLAALVSFVLAWF------ 78
Query: 129 NELCGQVATTPEDENEAQAGWIEGAAILFSVIIVVLVTAFNDWSKEKQFRGLQCRIEQEQ 188
E+ E ++E I+ ++ +V + + + E L+ E E
Sbjct: 79 -----------EEGEETTTAFVEPLVIMLILVANAIVGVWQERNAESAIEALK---EYEP 124
Query: 189 KFS-IIRNGQ--LIQLPVAEIVVGDIAQVKYGDLLPADGILIQ--GNDLKIDESSLTGES 243
+ +IR+ + + ++ +IV GDI +V GD +PAD LI+ L++D+S LTGES
Sbjct: 125 EMGKVIRSDRKGVQRIRARDIVPGDIVEVAVGDKVPADLRLIEIKSTTLRVDQSILTGES 184
Query: 244 DHVKK-----------SLDKDPMLLSGTHVMEGSGRMVVTAVGVNSQTGIILTLLGVNED 292
V K + DK ML SGT++ G AVGV TG+ T LG
Sbjct: 185 VSVTKHTEAIPDPRAVNQDKKNMLFSGTNITSGK------AVGVAVATGLH-TELG---- 233
Query: 293 DEGEKKKKGKKQGVPENRNKAKTQDGVALEIQPLNSQEGIDNEEKDKKAVKVPKKEKSVL 352
K + + + E++ L
Sbjct: 234 --------------------------------------------KIRSQMAAVEPERTPL 249
Query: 353 QGKLTRLAVQIGKAGLLMSALTVFILILYFVIDNFVINRRPWLPECTPIYIQYFVKFFII 412
Q KL Q+ A + + + V+++ + D P +++ V +F I
Sbjct: 250 QRKLDEFGRQLSHA-ISVICVAVWVINIGHFAD----------PAHGGSWLRGAVYYFKI 298
Query: 413 GITVLVVAVPEGLPLAVTISLAYSVKKMMKDNNLVRHLDACETMGNATAICSDKTGTLTM 472
+ + V A+PEGLP +T LA ++M + N +VR L + ET+G + ICSDKTGTLT
Sbjct: 299 AVALAVAAIPEGLPAVITTCLALGTRRMARKNAIVRSLPSVETLGCTSVICSDKTGTLTT 358
Query: 473 NRMTVVQAYIGG--------IHYRQIPSPDVFLPK-------------VLDLIVNGISIN 511
N+M+V + ++ +H I S + P+ D +V +I
Sbjct: 359 NQMSVCRMFVVAEADAGSCLLHEFTI-SGTTYTPEGEVRQGDQPVRCGQFDGLVELATIC 417
Query: 512 SAYTSKILPPEKEGGLPRQVGNKTECALLGFVTDLK---QDYQAVR--------NEVPEE 560
+ L + G+ +VG TE AL V + D QA+ N V ++
Sbjct: 418 ALCNDSALDYNEAKGVYEKVGEATETALTCLVEKMNVFDTDLQALSRVERAGACNTVIKQ 477
Query: 561 KLYKVYT--FNSVRKSMSTVIR----NPNG-GFRMYSKGASEIILRKCNRILDRKGE-AV 612
+ K +T F+ RKSMS +P G G +M+ KGA E ++ +C+ + R G
Sbjct: 478 LMRKEFTLEFSRDRKSMSVYCTPTRPHPTGQGSKMFVKGAPESVIERCSSV--RVGSRTA 535
Query: 613 PFKNKDRDDMVRTVIE-PMACDGLRTICIAYRDFDDTEPSWDNEN-----EILTELTCIA 666
P R+ ++ + + D LR + +A RD + + ++ + T+LT +
Sbjct: 536 PLTPTSREQILAKIRDWGSGSDTLRCLALATRDAPPRKEDMELDDCSKFVQYETDLTFVG 595
Query: 667 VVGIEDPVRPEVPDAIAKCKQAGITVRMVTGDNINTARAIATKCGILTPGDDFL--CLEG 724
VG+ DP RPEV I +C QAGI V M+TGDN TA AI + GI +D G
Sbjct: 596 CVGMLDPPRPEVAACITRCYQAGIRVVMITGDNKGTAVAICRRLGIFGDTEDVAGKAYTG 655
Query: 725 KEFNRLIRNEKGEVEQEKLDKIWPKLRVLARSSPTDKHTLVKGIIDSTVGEHRQVVAVTG 784
+EF+ ++ E+ + R AR P K +V+ + ++ A+TG
Sbjct: 656 REFD--------DLSPEQQRQACRTARCFARVEPAHKSRIVENL-----QSFNEITAMTG 702
Query: 785 DGTNDGPALKKADVGFAMGIAGTDVAKEASDIILTDDNFTSIVKAVMWGRNVYDSISKFL 844
DG ND PALKKA++G AMG +GT VAK A++++L+DDNF SIV AV GR +Y ++ +F+
Sbjct: 703 DGVNDAPALKKAEIGIAMG-SGTAVAKSAAEMVLSDDNFASIVAAVEEGRAIYSNMKQFI 761
Query: 845 QFQLTVNVVAVIVAFTGACITQDSPLKAVQMLWVNLIMDTFASLALATEPPTESLLKRRP 904
++ ++ NV V+ F A + L VQ+LWVNL+ D + AL PP ++++ P
Sbjct: 762 RYLISSNVGEVVCIFLTAILGLPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMEKLP 821
Query: 905 YGRNKPLISRTMMKNILGHAFYQLIVIFILV 935
+ LIS G F++ + I + V
Sbjct: 822 RSPREALIS--------GWLFFRYLAIGVYV 844
>gi|28373105 ATPase, Ca++ transporting, ubiquitous isoform e [Homo
sapiens]
Length = 1052
Score = 300 bits (767), Expect = 7e-81
Identities = 266/931 (28%), Positives = 431/931 (46%), Gaps = 175/931 (18%)
Query: 69 NPADLEKRRQVFGHNVIPPKKPKTFLELVWEALQDVTLIILEIAAIISLVLSFYRPAGEE 128
+PA + R+ +G N +P ++ K+ ELV E +D+ + IL +AA++S VL+++
Sbjct: 25 SPAQVTGARERYGPNELPSEEGKSLWELVLEQFEDLLVRILLLAALVSFVLAWF------ 78
Query: 129 NELCGQVATTPEDENEAQAGWIEGAAILFSVIIVVLVTAFNDWSKEKQFRGLQCRIEQEQ 188
E+ E ++E I+ ++ +V + + + E L+ E E
Sbjct: 79 -----------EEGEETTTAFVEPLVIMLILVANAIVGVWQERNAESAIEALK---EYEP 124
Query: 189 KFS-IIRNGQ--LIQLPVAEIVVGDIAQVKYGDLLPADGILIQ--GNDLKIDESSLTGES 243
+ +IR+ + + ++ +IV GDI +V GD +PAD LI+ L++D+S LTGES
Sbjct: 125 EMGKVIRSDRKGVQRIRARDIVPGDIVEVAVGDKVPADLRLIEIKSTTLRVDQSILTGES 184
Query: 244 DHVKK-----------SLDKDPMLLSGTHVMEGSGRMVVTAVGVNSQTGIILTLLGVNED 292
V K + DK ML SGT++ G AVGV TG+ T LG
Sbjct: 185 VSVTKHTEAIPDPRAVNQDKKNMLFSGTNITSGK------AVGVAVATGLH-TELG---- 233
Query: 293 DEGEKKKKGKKQGVPENRNKAKTQDGVALEIQPLNSQEGIDNEEKDKKAVKVPKKEKSVL 352
K + + + E++ L
Sbjct: 234 --------------------------------------------KIRSQMAAVEPERTPL 249
Query: 353 QGKLTRLAVQIGKAGLLMSALTVFILILYFVIDNFVINRRPWLPECTPIYIQYFVKFFII 412
Q KL Q+ A + + + V+++ + D P +++ V +F I
Sbjct: 250 QRKLDEFGRQLSHA-ISVICVAVWVINIGHFAD----------PAHGGSWLRGAVYYFKI 298
Query: 413 GITVLVVAVPEGLPLAVTISLAYSVKKMMKDNNLVRHLDACETMGNATAICSDKTGTLTM 472
+ + V A+PEGLP +T LA ++M + N +VR L + ET+G + ICSDKTGTLT
Sbjct: 299 AVALAVAAIPEGLPAVITTCLALGTRRMARKNAIVRSLPSVETLGCTSVICSDKTGTLTT 358
Query: 473 NRMTVVQAYIGG--------IHYRQIPSPDVFLPK-------------VLDLIVNGISIN 511
N+M+V + ++ +H I S + P+ D +V +I
Sbjct: 359 NQMSVCRMFVVAEADAGSCLLHEFTI-SGTTYTPEGEVRQGDQPVRCGQFDGLVELATIC 417
Query: 512 SAYTSKILPPEKEGGLPRQVGNKTECALLGFVTDLK---QDYQAVR--------NEVPEE 560
+ L + G+ +VG TE AL V + D QA+ N V ++
Sbjct: 418 ALCNDSALDYNEAKGVYEKVGEATETALTCLVEKMNVFDTDLQALSRVERAGACNTVIKQ 477
Query: 561 KLYKVYT--FNSVRKSMSTVIR----NPNG-GFRMYSKGASEIILRKCNRILDRKGE-AV 612
+ K +T F+ RKSMS +P G G +M+ KGA E ++ +C+ + R G
Sbjct: 478 LMRKEFTLEFSRDRKSMSVYCTPTRPHPTGQGSKMFVKGAPESVIERCSSV--RVGSRTA 535
Query: 613 PFKNKDRDDMVRTVIE-PMACDGLRTICIAYRDFDDTEPSWDNEN-----EILTELTCIA 666
P R+ ++ + + D LR + +A RD + + ++ + T+LT +
Sbjct: 536 PLTPTSREQILAKIRDWGSGSDTLRCLALATRDAPPRKEDMELDDCSKFVQYETDLTFVG 595
Query: 667 VVGIEDPVRPEVPDAIAKCKQAGITVRMVTGDNINTARAIATKCGILTPGDDFL--CLEG 724
VG+ DP RPEV I +C QAGI V M+TGDN TA AI + GI +D G
Sbjct: 596 CVGMLDPPRPEVAACITRCYQAGIRVVMITGDNKGTAVAICRRLGIFGDTEDVAGKAYTG 655
Query: 725 KEFNRLIRNEKGEVEQEKLDKIWPKLRVLARSSPTDKHTLVKGIIDSTVGEHRQVVAVTG 784
+EF+ ++ E+ + R AR P K +V+ + ++ A+TG
Sbjct: 656 REFD--------DLSPEQQRQACRTARCFARVEPAHKSRIVENL-----QSFNEITAMTG 702
Query: 785 DGTNDGPALKKADVGFAMGIAGTDVAKEASDIILTDDNFTSIVKAVMWGRNVYDSISKFL 844
DG ND PALKKA++G AMG +GT VAK A++++L+DDNF SIV AV GR +Y ++ +F+
Sbjct: 703 DGVNDAPALKKAEIGIAMG-SGTAVAKSAAEMVLSDDNFASIVAAVEEGRAIYSNMKQFI 761
Query: 845 QFQLTVNVVAVIVAFTGACITQDSPLKAVQMLWVNLIMDTFASLALATEPPTESLLKRRP 904
++ ++ NV V+ F A + L VQ+LWVNL+ D + AL PP ++++ P
Sbjct: 762 RYLISSNVGEVVCIFLTAILGLPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMEKLP 821
Query: 905 YGRNKPLISRTMMKNILGHAFYQLIVIFILV 935
+ LIS G F++ + I + V
Sbjct: 822 RSPREALIS--------GWLFFRYLAIGVYV 844
>gi|10835220 ATPase, Ca++ transporting, fast twitch 1 isoform b
[Homo sapiens]
Length = 994
Score = 295 bits (754), Expect = 2e-79
Identities = 265/904 (29%), Positives = 411/904 (45%), Gaps = 159/904 (17%)
Query: 70 PADLEKRRQVFGHNVIPPKKPKTFLELVWEALQDVTLIILEIAAIISLVLSFYRPAGEEN 129
P +++ + +G N +P ++ KT ELV E +D+ + IL +AA IS VL+++
Sbjct: 26 PDQVKRNLEKYGLNELPAEEGKTLWELVIEQFEDLLVRILLLAACISFVLAWF------- 78
Query: 130 ELCGQVATTPEDENEAQAGWIEGAAILFSVIIVVLVTAFNDWSKEKQFRGLQCRIEQEQK 189
E+ E ++E IL +I +V + + + E L+ + K
Sbjct: 79 ----------EEGEETITAFVEPFVILLILIANAIVGVWQERNAENAIEALKEYEPEMGK 128
Query: 190 FSIIRNGQLIQLPVAEIVVGDIAQVKYGDLLPADG--ILIQGNDLKIDESSLTGESDHVK 247
+ ++ +IV GDI +V GD +PAD + I+ L++D+S LTGES V
Sbjct: 129 VYRADRKSVQRIKARDIVPGDIVEVAVGDKVPADIRILAIKSTTLRVDQSILTGESVSVI 188
Query: 248 K-----------SLDKDPMLLSGTHVMEGSGRMVVTAVGVNSQTGIILTLLGVNEDDEGE 296
K + DK ML SGT++ G A+G+ + TG+
Sbjct: 189 KHTEPVPDPRAVNQDKKNMLFSGTNIAAGK------ALGIVATTGV-------------- 228
Query: 297 KKKKGKKQGVPENRNKAKTQDGVALEIQPLNSQEGIDNEEKDKKAVKVPKKEKSVLQGKL 356
G + G ++ A QD K+ LQ KL
Sbjct: 229 ----GTEIGKIRDQMAATEQD-------------------------------KTPLQQKL 253
Query: 357 TRLAVQIGKAGLLMSALTVFILILYFVIDNFVINRRPWLPECTPIYIQYFVKFFIIGITV 416
Q+ K L+ I I +F N ++ W + +F I + +
Sbjct: 254 DEFGEQLSKVISLICVAVWLINIGHF---NDPVHGGSWFRGA--------IYYFKIAVAL 302
Query: 417 LVVAVPEGLPLAVTISLAYSVKKMMKDNNLVRHLDACETMGNATAICSDKTGTLTMNRMT 476
V A+PEGLP +T LA ++M K N +VR L + ET+G + ICSDKTGTLT N+M+
Sbjct: 303 AVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQMS 362
Query: 477 VVQAYI-----------------GGIHYRQ---IPSPDVFLPKVLDLIVNGISINSAYTS 516
V + +I G + + + + P D +V +I +
Sbjct: 363 VCKMFIIDKVDGDICLLNEFSITGSTYAPEGEVLKNDKPVRPGQYDGLVELATICALCND 422
Query: 517 KILPPEKEGGLPRQVGNKTECALLGFV-------TDLKQDYQAVR----NEVPEEKLYKV 565
L + G+ +VG TE AL V TD++ + R N V + + K
Sbjct: 423 SSLDFNEAKGVYEKVGEATETALTTLVEKMNVFNTDVRSLSKVERANACNSVIRQLMKKE 482
Query: 566 YT--FNSVRKSMSTVIRNPNG-----GFRMYSKGASEIILRKCNRILDRKGEA-VPFKNK 617
+T F+ RKSMS G +M+ KGA E ++ +CN + R G VP
Sbjct: 483 FTLEFSRDRKSMSVYCSPAKSSRAAVGNKMFVKGAPEGVIDRCNYV--RVGTTRVPLTGP 540
Query: 618 DRDDMVRTVIE-PMACDGLRTICIAYRDFDDT--EPSWDNENEIL---TELTCIAVVGIE 671
++ ++ + E D LR + +A RD E D+ L T+LT + VVG+
Sbjct: 541 VKEKIMAVIKEWGTGRDTLRCLALATRDTPPKREEMVLDDSARFLEYETDLTFVGVVGML 600
Query: 672 DPVRPEVPDAIAKCKQAGITVRMVTGDNINTARAIATKCGILTPGDDFL--CLEGKEFNR 729
DP R EV +I C+ AGI V M+TGDN TA AI + GI ++ G+EF+
Sbjct: 601 DPPRKEVTGSIQLCRDAGIRVIMITGDNKGTAIAICRRIGIFGENEEVADRAYTGREFDD 660
Query: 730 LIRNEKGEVEQEKLDKIWPKLRVLARSSPTDKHTLVKGIIDSTVGEHRQVVAVTGDGTND 789
L E+ E + AR P+ K +V+ + + ++ A+TGDG ND
Sbjct: 661 LPLAEQREACRRAC--------CFARVEPSHKSKIVEYL-----QSYDEITAMTGDGVND 707
Query: 790 GPALKKADVGFAMGIAGTDVAKEASDIILTDDNFTSIVKAVMWGRNVYDSISKFLQFQLT 849
PALKKA++G AMG +GT VAK AS+++L DDNF++IV AV GR +Y+++ +F+++ ++
Sbjct: 708 APALKKAEIGIAMG-SGTAVAKTASEMVLADDNFSTIVAAVEEGRAIYNNMKQFIRYLIS 766
Query: 850 VNVVAVIVAFTGACITQDSPLKAVQMLWVNLIMDTFASLALATEPPTESLLKRRPYGRNK 909
NV V+ F A + L VQ+LWVNL+ D + AL PP ++ R P +
Sbjct: 767 SNVGEVVCIFLTAALGLPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMDRPPRSPKE 826
Query: 910 PLIS 913
PLIS
Sbjct: 827 PLIS 830
>gi|27886529 ATPase, Ca++ transporting, fast twitch 1 isoform a
[Homo sapiens]
Length = 1001
Score = 295 bits (754), Expect = 2e-79
Identities = 265/904 (29%), Positives = 411/904 (45%), Gaps = 159/904 (17%)
Query: 70 PADLEKRRQVFGHNVIPPKKPKTFLELVWEALQDVTLIILEIAAIISLVLSFYRPAGEEN 129
P +++ + +G N +P ++ KT ELV E +D+ + IL +AA IS VL+++
Sbjct: 26 PDQVKRNLEKYGLNELPAEEGKTLWELVIEQFEDLLVRILLLAACISFVLAWF------- 78
Query: 130 ELCGQVATTPEDENEAQAGWIEGAAILFSVIIVVLVTAFNDWSKEKQFRGLQCRIEQEQK 189
E+ E ++E IL +I +V + + + E L+ + K
Sbjct: 79 ----------EEGEETITAFVEPFVILLILIANAIVGVWQERNAENAIEALKEYEPEMGK 128
Query: 190 FSIIRNGQLIQLPVAEIVVGDIAQVKYGDLLPADG--ILIQGNDLKIDESSLTGESDHVK 247
+ ++ +IV GDI +V GD +PAD + I+ L++D+S LTGES V
Sbjct: 129 VYRADRKSVQRIKARDIVPGDIVEVAVGDKVPADIRILAIKSTTLRVDQSILTGESVSVI 188
Query: 248 K-----------SLDKDPMLLSGTHVMEGSGRMVVTAVGVNSQTGIILTLLGVNEDDEGE 296
K + DK ML SGT++ G A+G+ + TG+
Sbjct: 189 KHTEPVPDPRAVNQDKKNMLFSGTNIAAGK------ALGIVATTGV-------------- 228
Query: 297 KKKKGKKQGVPENRNKAKTQDGVALEIQPLNSQEGIDNEEKDKKAVKVPKKEKSVLQGKL 356
G + G ++ A QD K+ LQ KL
Sbjct: 229 ----GTEIGKIRDQMAATEQD-------------------------------KTPLQQKL 253
Query: 357 TRLAVQIGKAGLLMSALTVFILILYFVIDNFVINRRPWLPECTPIYIQYFVKFFIIGITV 416
Q+ K L+ I I +F N ++ W + +F I + +
Sbjct: 254 DEFGEQLSKVISLICVAVWLINIGHF---NDPVHGGSWFRGA--------IYYFKIAVAL 302
Query: 417 LVVAVPEGLPLAVTISLAYSVKKMMKDNNLVRHLDACETMGNATAICSDKTGTLTMNRMT 476
V A+PEGLP +T LA ++M K N +VR L + ET+G + ICSDKTGTLT N+M+
Sbjct: 303 AVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQMS 362
Query: 477 VVQAYI-----------------GGIHYRQ---IPSPDVFLPKVLDLIVNGISINSAYTS 516
V + +I G + + + + P D +V +I +
Sbjct: 363 VCKMFIIDKVDGDICLLNEFSITGSTYAPEGEVLKNDKPVRPGQYDGLVELATICALCND 422
Query: 517 KILPPEKEGGLPRQVGNKTECALLGFV-------TDLKQDYQAVR----NEVPEEKLYKV 565
L + G+ +VG TE AL V TD++ + R N V + + K
Sbjct: 423 SSLDFNEAKGVYEKVGEATETALTTLVEKMNVFNTDVRSLSKVERANACNSVIRQLMKKE 482
Query: 566 YT--FNSVRKSMSTVIRNPNG-----GFRMYSKGASEIILRKCNRILDRKGEA-VPFKNK 617
+T F+ RKSMS G +M+ KGA E ++ +CN + R G VP
Sbjct: 483 FTLEFSRDRKSMSVYCSPAKSSRAAVGNKMFVKGAPEGVIDRCNYV--RVGTTRVPLTGP 540
Query: 618 DRDDMVRTVIE-PMACDGLRTICIAYRDFDDT--EPSWDNENEIL---TELTCIAVVGIE 671
++ ++ + E D LR + +A RD E D+ L T+LT + VVG+
Sbjct: 541 VKEKIMAVIKEWGTGRDTLRCLALATRDTPPKREEMVLDDSARFLEYETDLTFVGVVGML 600
Query: 672 DPVRPEVPDAIAKCKQAGITVRMVTGDNINTARAIATKCGILTPGDDFL--CLEGKEFNR 729
DP R EV +I C+ AGI V M+TGDN TA AI + GI ++ G+EF+
Sbjct: 601 DPPRKEVTGSIQLCRDAGIRVIMITGDNKGTAIAICRRIGIFGENEEVADRAYTGREFDD 660
Query: 730 LIRNEKGEVEQEKLDKIWPKLRVLARSSPTDKHTLVKGIIDSTVGEHRQVVAVTGDGTND 789
L E+ E + AR P+ K +V+ + + ++ A+TGDG ND
Sbjct: 661 LPLAEQREACRRAC--------CFARVEPSHKSKIVEYL-----QSYDEITAMTGDGVND 707
Query: 790 GPALKKADVGFAMGIAGTDVAKEASDIILTDDNFTSIVKAVMWGRNVYDSISKFLQFQLT 849
PALKKA++G AMG +GT VAK AS+++L DDNF++IV AV GR +Y+++ +F+++ ++
Sbjct: 708 APALKKAEIGIAMG-SGTAVAKTASEMVLADDNFSTIVAAVEEGRAIYNNMKQFIRYLIS 766
Query: 850 VNVVAVIVAFTGACITQDSPLKAVQMLWVNLIMDTFASLALATEPPTESLLKRRPYGRNK 909
NV V+ F A + L VQ+LWVNL+ D + AL PP ++ R P +
Sbjct: 767 SNVGEVVCIFLTAALGLPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMDRPPRSPKE 826
Query: 910 PLIS 913
PLIS
Sbjct: 827 PLIS 830
>gi|24638454 ATPase, Ca++ transporting, slow twitch 2 isoform 1 [Homo
sapiens]
Length = 1042
Score = 294 bits (752), Expect = 4e-79
Identities = 303/1109 (27%), Positives = 483/1109 (43%), Gaps = 195/1109 (17%)
Query: 45 NVHYGGVQNLCSRLKTSPVEGLSGNPADLEKRRQVFGHNVIPPKKPKTFLELVWEALQDV 104
N H V+ + + GLS ++K ++ +G N +P ++ KT LELV E +D+
Sbjct: 3 NAHTKTVEEVLGHFGVNESTGLSLE--QVKKLKERWGSNELPAEEGKTLLELVIEQFEDL 60
Query: 105 TLIILEIAAIISLVLSFYRPAGEENELCGQVATTPEDENEAQAGWIEGAAILFSVIIVVL 164
+ IL +AA IS VL+++ E+ E ++E IL ++ +
Sbjct: 61 LVRILLLAACISFVLAWF-----------------EEGEETITAFVEPFVILLILVANAI 103
Query: 165 VTAFNDWSKEKQFRGLQCRIEQEQKFSIIRNGQLIQ-LPVAEIVVGDIAQVKYGDLLPAD 223
V + + + E L+ E E ++ + +Q + +IV GDI ++ GD +PAD
Sbjct: 104 VGVWQERNAENAIEALK-EYEPEMGKVYRQDRKSVQRIKAKDIVPGDIVEIAVGDKVPAD 162
Query: 224 GIL--IQGNDLKIDESSLTGESDHVKKSLDKDP-----------MLLSGTHVMEGSGRMV 270
L I+ L++D+S LTGES V K D P ML SGT++ G
Sbjct: 163 IRLTSIKSTTLRVDQSILTGESVSVIKHTDPVPDPRAVNQDKKNMLFSGTNIAAGK---- 218
Query: 271 VTAVGVNSQTGIILTLLGVNEDDEGEKKKKGKKQGVPENRNKAKTQDGVALEIQPLNSQE 330
A+GV TG+ N++
Sbjct: 219 --AMGVVVATGV--------------------------------------------NTEI 232
Query: 331 GIDNEEKDKKAVKVPKKEKSVLQGKLTRLAVQIGKAGLLMSALTVFILILYFVIDNFVIN 390
G K + + ++E++ LQ KL Q+ K ++S + + + I+ N ++
Sbjct: 233 G-----KIRDEMVATEQERTPLQQKLDEFGEQLSK---VISLICIAVWIINIGHFNDPVH 284
Query: 391 RRPWLPECTPIYIQYFVKFFIIGITVLVVAVPEGLPLAVTISLAYSVKKMMKDNNLVRHL 450
W I+ + +F I + + V A+PEGLP +T LA ++M K N +VR L
Sbjct: 285 GGSW--------IRGAIYYFKIAVALAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSL 336
Query: 451 DACETMGNATAICSDKTGTLTMNRMTVVQAYI------------------------GGIH 486
+ ET+G + ICSDKTGTLT N+M+V + +I G +H
Sbjct: 337 PSVETLGCTSVICSDKTGTLTTNQMSVCRMFILDRVEGDTCSLNEFTITGSTYAPIGEVH 396
Query: 487 YRQIPSPDVFLPKVLDLIVNGISINSAYTSKILPPEKEGGLPRQVGNKTECALLGFV--- 543
P D +V +I + L + G+ +VG TE AL V
Sbjct: 397 KDDKPVNC----HQYDGLVELATICALCNDSALDYNEAKGVYEKVGEATETALTCLVEKM 452
Query: 544 ----TDLKQDYQAVR----NEVPEEKLYKVYT--FNSVRKSMSTVIRNPNGGFR-----M 588
T+LK + R N V ++ + K +T F+ RKSMS V PN R M
Sbjct: 453 NVFDTELKGLSKIERANACNSVIKQLMKKEFTLEFSRDRKSMS-VYCTPNKPSRTSMSKM 511
Query: 589 YSKGASEIILRKCNRILDRKGEA-VPFKNKDRDDMVRTVIE-PMACDGLRTICIAYRDFD 646
+ KGA E ++ +C I R G VP + + ++ + E D LR + +A D
Sbjct: 512 FVKGAPEGVIDRCTHI--RVGSTKVPMTSGVKQKIMSVIREWGSGSDTLRCLALATHDNP 569
Query: 647 DTEPSW---DNENEIL--TELTCIAVVGIEDPVRPEVPDAIAKCKQAGITVRMVTGDNIN 701
D+ N I T LT + VG+ DP R EV ++ C+QAGI V M+TGDN
Sbjct: 570 LRREEMHLEDSANFIKYETNLTFVGCVGMLDPPRIEVASSVKLCRQAGIRVIMITGDNKG 629
Query: 702 TARAIATKCGILTPGDDFL--CLEGKEFNRLIRNEKGEVEQEKLDKIWPKLRVLARSSPT 759
TA AI + GI +D G+EF+ L + + + R AR P+
Sbjct: 630 TAVAICRRIGIFGQDEDVTSKAFTGREFDELNPSAQRDA--------CLNARCFARVEPS 681
Query: 760 DKHTLVKGIIDSTVGEHRQVVAVTGDGTNDGPALKKADVGFAMGIAGTDVAKEASDIILT 819
K +V+ + ++ A+TGDG ND PALKKA++G AMG +GT VAK AS+++L
Sbjct: 682 HKSKIVEFL-----QSFDEITAMTGDGVNDAPALKKAEIGIAMG-SGTAVAKTASEMVLA 735
Query: 820 DDNFTSIVKAVMWGRNVYDSISKFLQFQLTVNVVAVIVAFTGACITQDSPLKAVQMLWVN 879
DDNF++IV AV GR +Y+++ +F+++ ++ NV V+ F A + L VQ+LWVN
Sbjct: 736 DDNFSTIVAAVEEGRAIYNNMKQFIRYLISSNVGEVVCIFLTAALGFPEALIPVQLLWVN 795
Query: 880 LIMDTFASLALATEPPTESLLKRRPYGRNKPLISRTMMKNILGHAFYQLIVI-------F 932
L+ D + AL PP ++ + P +PLIS + L Y F
Sbjct: 796 LVTDGLPATALGFNPPDLDIMNKPPRNPKEPLISGWLFFRYLAIGCYVGAATVGAAAWWF 855
Query: 933 ILVFAGEK--FFDIDSGRKAPLHSPPSQ-----------HYTIVFNTFVLMQLFNEINSR 979
I G + F+ + + +P + T+ + V +++ N +NS
Sbjct: 856 IAADGGPRVSFYQLSHFLQCKEDNPDFEGVDCAIFESPYPMTMALSVLVTIEMCNALNSL 915
Query: 980 KIHGEKNVFSGIYRNIIFCSVVLGTFICQIFIVEFGGKP--FSCTSLSLSQWLWCLFIGI 1037
+ + + NI + + I+ P F T L+++QWL L I +
Sbjct: 916 S-ENQSLLRMPPWENIWLVGSICLSMSLHFLILYVEPLPLIFQITPLNVTQWLMVLKISL 974
Query: 1038 GELLWGQFISAIPTRSLKFLKEAGHGTTK 1066
+L + + + L+ KE TK
Sbjct: 975 PVILMDETLKFVARNYLEPGKECVQPATK 1003
>gi|4502285 ATPase, Ca++ transporting, slow twitch 2 isoform 2 [Homo
sapiens]
Length = 997
Score = 291 bits (745), Expect = 2e-78
Identities = 299/1098 (27%), Positives = 479/1098 (43%), Gaps = 195/1098 (17%)
Query: 45 NVHYGGVQNLCSRLKTSPVEGLSGNPADLEKRRQVFGHNVIPPKKPKTFLELVWEALQDV 104
N H V+ + + GLS ++K ++ +G N +P ++ KT LELV E +D+
Sbjct: 3 NAHTKTVEEVLGHFGVNESTGLSLE--QVKKLKERWGSNELPAEEGKTLLELVIEQFEDL 60
Query: 105 TLIILEIAAIISLVLSFYRPAGEENELCGQVATTPEDENEAQAGWIEGAAILFSVIIVVL 164
+ IL +AA IS VL+++ E+ E ++E IL ++ +
Sbjct: 61 LVRILLLAACISFVLAWF-----------------EEGEETITAFVEPFVILLILVANAI 103
Query: 165 VTAFNDWSKEKQFRGLQCRIEQEQKFSIIRNGQLIQ-LPVAEIVVGDIAQVKYGDLLPAD 223
V + + + E L+ E E ++ + +Q + +IV GDI ++ GD +PAD
Sbjct: 104 VGVWQERNAENAIEALK-EYEPEMGKVYRQDRKSVQRIKAKDIVPGDIVEIAVGDKVPAD 162
Query: 224 GIL--IQGNDLKIDESSLTGESDHVKKSLDKDP-----------MLLSGTHVMEGSGRMV 270
L I+ L++D+S LTGES V K D P ML SGT++ G
Sbjct: 163 IRLTSIKSTTLRVDQSILTGESVSVIKHTDPVPDPRAVNQDKKNMLFSGTNIAAGK---- 218
Query: 271 VTAVGVNSQTGIILTLLGVNEDDEGEKKKKGKKQGVPENRNKAKTQDGVALEIQPLNSQE 330
A+GV TG+ N++
Sbjct: 219 --AMGVVVATGV--------------------------------------------NTEI 232
Query: 331 GIDNEEKDKKAVKVPKKEKSVLQGKLTRLAVQIGKAGLLMSALTVFILILYFVIDNFVIN 390
G K + + ++E++ LQ KL Q+ K ++S + + + I+ N ++
Sbjct: 233 G-----KIRDEMVATEQERTPLQQKLDEFGEQLSK---VISLICIAVWIINIGHFNDPVH 284
Query: 391 RRPWLPECTPIYIQYFVKFFIIGITVLVVAVPEGLPLAVTISLAYSVKKMMKDNNLVRHL 450
W I+ + +F I + + V A+PEGLP +T LA ++M K N +VR L
Sbjct: 285 GGSW--------IRGAIYYFKIAVALAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSL 336
Query: 451 DACETMGNATAICSDKTGTLTMNRMTVVQAYI------------------------GGIH 486
+ ET+G + ICSDKTGTLT N+M+V + +I G +H
Sbjct: 337 PSVETLGCTSVICSDKTGTLTTNQMSVCRMFILDRVEGDTCSLNEFTITGSTYAPIGEVH 396
Query: 487 YRQIPSPDVFLPKVLDLIVNGISINSAYTSKILPPEKEGGLPRQVGNKTECALLGFV--- 543
P D +V +I + L + G+ +VG TE AL V
Sbjct: 397 KDDKPVNC----HQYDGLVELATICALCNDSALDYNEAKGVYEKVGEATETALTCLVEKM 452
Query: 544 ----TDLKQDYQAVR----NEVPEEKLYKVYT--FNSVRKSMSTVIRNPNGGFR-----M 588
T+LK + R N V ++ + K +T F+ RKSMS V PN R M
Sbjct: 453 NVFDTELKGLSKIERANACNSVIKQLMKKEFTLEFSRDRKSMS-VYCTPNKPSRTSMSKM 511
Query: 589 YSKGASEIILRKCNRILDRKGEA-VPFKNKDRDDMVRTVIE-PMACDGLRTICIAYRDFD 646
+ KGA E ++ +C I R G VP + + ++ + E D LR + +A D
Sbjct: 512 FVKGAPEGVIDRCTHI--RVGSTKVPMTSGVKQKIMSVIREWGSGSDTLRCLALATHDNP 569
Query: 647 DTEPSW---DNENEIL--TELTCIAVVGIEDPVRPEVPDAIAKCKQAGITVRMVTGDNIN 701
D+ N I T LT + VG+ DP R EV ++ C+QAGI V M+TGDN
Sbjct: 570 LRREEMHLEDSANFIKYETNLTFVGCVGMLDPPRIEVASSVKLCRQAGIRVIMITGDNKG 629
Query: 702 TARAIATKCGILTPGDDFL--CLEGKEFNRLIRNEKGEVEQEKLDKIWPKLRVLARSSPT 759
TA AI + GI +D G+EF+ L + + + R AR P+
Sbjct: 630 TAVAICRRIGIFGQDEDVTSKAFTGREFDELNPSAQRDA--------CLNARCFARVEPS 681
Query: 760 DKHTLVKGIIDSTVGEHRQVVAVTGDGTNDGPALKKADVGFAMGIAGTDVAKEASDIILT 819
K +V+ + ++ A+TGDG ND PALKKA++G AMG +GT VAK AS+++L
Sbjct: 682 HKSKIVEFL-----QSFDEITAMTGDGVNDAPALKKAEIGIAMG-SGTAVAKTASEMVLA 735
Query: 820 DDNFTSIVKAVMWGRNVYDSISKFLQFQLTVNVVAVIVAFTGACITQDSPLKAVQMLWVN 879
DDNF++IV AV GR +Y+++ +F+++ ++ NV V+ F A + L VQ+LWVN
Sbjct: 736 DDNFSTIVAAVEEGRAIYNNMKQFIRYLISSNVGEVVCIFLTAALGFPEALIPVQLLWVN 795
Query: 880 LIMDTFASLALATEPPTESLLKRRPYGRNKPLISRTMMKNILGHAFYQLIVI-------F 932
L+ D + AL PP ++ + P +PLIS + L Y F
Sbjct: 796 LVTDGLPATALGFNPPDLDIMNKPPRNPKEPLISGWLFFRYLAIGCYVGAATVGAAAWWF 855
Query: 933 ILVFAGEK--FFDIDSGRKAPLHSPPSQ-----------HYTIVFNTFVLMQLFNEINSR 979
I G + F+ + + +P + T+ + V +++ N +NS
Sbjct: 856 IAADGGPRVSFYQLSHFLQCKEDNPDFEGVDCAIFESPYPMTMALSVLVTIEMCNALNSL 915
Query: 980 KIHGEKNVFSGIYRNIIFCSVVLGTFICQIFIVEFGGKP--FSCTSLSLSQWLWCLFIGI 1037
+ + + NI + + I+ P F T L+++QWL L I +
Sbjct: 916 S-ENQSLLRMPPWENIWLVGSICLSMSLHFLILYVEPLPLIFQITPLNVTQWLMVLKISL 974
Query: 1038 GELLWGQFISAIPTRSLK 1055
+L + + + L+
Sbjct: 975 PVILMDETLKFVARNYLE 992
>gi|48762691 calcium-transporting ATPase 2C1 isoform 1b [Homo sapiens]
Length = 939
Score = 290 bits (743), Expect = 4e-78
Identities = 253/910 (27%), Positives = 420/910 (46%), Gaps = 156/910 (17%)
Query: 151 EGAAILFSVIIVVLVTAFNDWSKEKQFRGLQCRIEQEQKFSIIRNGQLIQLPVAEIVVGD 210
+ +I +++IVV V ++ EK L + E +R G+L ++V GD
Sbjct: 102 DAVSITVAILIVVTVAFVQEYRSEKSLEELSKLVPPE--CHCVREGKLEHTLARDLVPGD 159
Query: 211 IAQVKYGDLLPADGILIQGNDLKIDESSLTGESDHVKKSLDKDPMLLSGTHVMEGSGRMV 270
+ GD +PAD L + DL IDESSLTGE+ K P +G + + R
Sbjct: 160 TVCLSVGDRVPADLRLFEAVDLSIDESSLTGETTPCSKVTAPQPAATNG----DLASRSN 215
Query: 271 VTAVGVNSQTGIILTLLGVNEDDEGEKKKKGKKQGVPENRNKAKTQDGVALEIQPLNSQE 330
+ +G + G K KG G EN ++ G ++
Sbjct: 216 IAFMGTLVRCG----------------KAKGVVIGTGEN-----SEFGEVFKMM------ 248
Query: 331 GIDNEEKDKKAVKVPKKEKSVLQGKLTRLAVQIGKAGLLMSALTVFILILYFVIDNFVIN 390
+ ++A K P ++ L GK G G++M
Sbjct: 249 ------QAEEAPKTPLQKSMDLLGKQLSF-YSFGIIGIIMLV------------------ 283
Query: 391 RRPWLPECTPIYIQYFVKFFIIGITVLVVAVPEGLPLAVTISLAYSVKKMMKDNNLVRHL 450
WL + ++ F I +++ V A+PEGLP+ VT++LA V +M+K +V+ L
Sbjct: 284 --GWLLG------KDILEMFTISVSLAVAAIPEGLPIVVTVTLALGVMRMVKKRAIVKKL 335
Query: 451 DACETMGNATAICSDKTGTLTMNRMTV--------VQAYIGGIHYRQIPSPDVFLPKVLD 502
ET+G ICSDKTGTLT N MTV + A + G+ Y Q +
Sbjct: 336 PIVETLGCCNVICSDKTGTLTKNEMTVTHIFTSDGLHAEVTGVGYNQFG----------E 385
Query: 503 LIVNGISINSAYTSKILPPEKEGGLPRQ--------VGNKTECALLGF-----VTDLKQD 549
+IV+G ++ Y + + G + +G TE AL+ + L+QD
Sbjct: 386 VIVDGDVVHGFYNPAVSRIVEAGCVCNDAVIRNNTLMGKPTEGALIALAMKMGLDGLQQD 445
Query: 550 YQAVRNEVPEEKLYKVYTFNSVRKSMSTVIRNPNGGFR---MYSKGASEIILRKCNRILD 606
Y +R Y F+S +K M+ + R + KGA E +++ C
Sbjct: 446 Y--IRKAE--------YPFSSEQKWMAVKCVHRTQQDRPEICFMKGAYEQVIKYCTTY-Q 494
Query: 607 RKGEAVPFKNKDRDDMVRTVIEPMACDGLRTICIAYRDFDDTEPSWDNENEILTELTCIA 666
KG+ + + RD + + M GLR + +A L +LT +
Sbjct: 495 SKGQTLTLTQQQRD-VYQQEKARMGSAGLRVLALA-------------SGPELGQLTFLG 540
Query: 667 VVGIEDPVRPEVPDAIAKCKQAGITVRMVTGDNINTARAIATKCGILTPGDDFLCLEGKE 726
+VGI DP R V +A+ +G++++M+TGD+ TA AIA++ G+ + + G+E
Sbjct: 541 LVGIIDPPRTGVKEAVTTLIASGVSIKMITGDSQETAVAIASRLGLYSKTSQ--SVSGEE 598
Query: 727 FNRLIRNEKGEVEQEKLDKIWPKLRVLARSSPTDKHTLVKGIIDSTVGEHRQVVAVTGDG 786
+ + + ++L +I PK+ V R+SP K ++K + ++ VVA+TGDG
Sbjct: 599 IDAM--------DVQQLSQIVPKVAVFYRASPRHKMKIIKSL-----QKNGSVVAMTGDG 645
Query: 787 TNDGPALKKADVGFAMGIAGTDVAKEASDIILTDDNFTSIVKAVMWGRNVYDSISKFLQF 846
ND ALK AD+G AMG GTDV KEA+D+IL DD+F +I+ A+ G+ +Y++I F++F
Sbjct: 646 VNDAVALKAADIGVAMGQTGTDVCKEAADMILVDDDFQTIMSAIEEGKGIYNNIKNFVRF 705
Query: 847 QLTVNVVAVIVAFTGACITQDSPLKAVQMLWVNLIMDTFASLALATEPPTESLLKRRPYG 906
QL+ ++ A+ + + +PL A+Q+LW+N+IMD + +L EP + ++++ P
Sbjct: 706 QLSTSIAALTLISLATLMNFPNPLNAMQILWINIIMDGPPAQSLGVEPVDKDVIRKPPRN 765
Query: 907 RNKPLISRTMMKNILGHAFYQLIVIFILVFAGEKFFDIDSGRKAPLHSPPSQHYTIVFNT 966
++++ ++ IL V I++ G F R+ + + T+ F
Sbjct: 766 WKDSILTKNLILKIL--------VSSIIIVCGTLFV---FWRELRDNVITPRDTTMTFTC 814
Query: 967 FVLMQLFNEINSRKIHGEKNVFS-GIYRNIIFCSVVLGTFICQIFIVEFG--GKPFSCTS 1023
FV +FN ++SR K+VF G+ N +FC VLG+ + Q+ ++ F K F S
Sbjct: 815 FVFFDMFNALSSRS--QTKSVFEIGLCSNRMFCYAVLGSIMGQLLVIYFPPLQKVFQTES 872
Query: 1024 LSLSQWLWCL 1033
LS+ L+ L
Sbjct: 873 LSILDLLFLL 882
>gi|48762689 calcium-transporting ATPase 2C1 isoform 1d [Homo sapiens]
Length = 949
Score = 290 bits (743), Expect = 4e-78
Identities = 253/910 (27%), Positives = 420/910 (46%), Gaps = 156/910 (17%)
Query: 151 EGAAILFSVIIVVLVTAFNDWSKEKQFRGLQCRIEQEQKFSIIRNGQLIQLPVAEIVVGD 210
+ +I +++IVV V ++ EK L + E +R G+L ++V GD
Sbjct: 102 DAVSITVAILIVVTVAFVQEYRSEKSLEELSKLVPPE--CHCVREGKLEHTLARDLVPGD 159
Query: 211 IAQVKYGDLLPADGILIQGNDLKIDESSLTGESDHVKKSLDKDPMLLSGTHVMEGSGRMV 270
+ GD +PAD L + DL IDESSLTGE+ K P +G + + R
Sbjct: 160 TVCLSVGDRVPADLRLFEAVDLSIDESSLTGETTPCSKVTAPQPAATNG----DLASRSN 215
Query: 271 VTAVGVNSQTGIILTLLGVNEDDEGEKKKKGKKQGVPENRNKAKTQDGVALEIQPLNSQE 330
+ +G + G K KG G EN ++ G ++
Sbjct: 216 IAFMGTLVRCG----------------KAKGVVIGTGEN-----SEFGEVFKMM------ 248
Query: 331 GIDNEEKDKKAVKVPKKEKSVLQGKLTRLAVQIGKAGLLMSALTVFILILYFVIDNFVIN 390
+ ++A K P ++ L GK G G++M
Sbjct: 249 ------QAEEAPKTPLQKSMDLLGKQLSF-YSFGIIGIIMLV------------------ 283
Query: 391 RRPWLPECTPIYIQYFVKFFIIGITVLVVAVPEGLPLAVTISLAYSVKKMMKDNNLVRHL 450
WL + ++ F I +++ V A+PEGLP+ VT++LA V +M+K +V+ L
Sbjct: 284 --GWLLG------KDILEMFTISVSLAVAAIPEGLPIVVTVTLALGVMRMVKKRAIVKKL 335
Query: 451 DACETMGNATAICSDKTGTLTMNRMTV--------VQAYIGGIHYRQIPSPDVFLPKVLD 502
ET+G ICSDKTGTLT N MTV + A + G+ Y Q +
Sbjct: 336 PIVETLGCCNVICSDKTGTLTKNEMTVTHIFTSDGLHAEVTGVGYNQFG----------E 385
Query: 503 LIVNGISINSAYTSKILPPEKEGGLPRQ--------VGNKTECALLGF-----VTDLKQD 549
+IV+G ++ Y + + G + +G TE AL+ + L+QD
Sbjct: 386 VIVDGDVVHGFYNPAVSRIVEAGCVCNDAVIRNNTLMGKPTEGALIALAMKMGLDGLQQD 445
Query: 550 YQAVRNEVPEEKLYKVYTFNSVRKSMSTVIRNPNGGFR---MYSKGASEIILRKCNRILD 606
Y +R Y F+S +K M+ + R + KGA E +++ C
Sbjct: 446 Y--IRKAE--------YPFSSEQKWMAVKCVHRTQQDRPEICFMKGAYEQVIKYCTTY-Q 494
Query: 607 RKGEAVPFKNKDRDDMVRTVIEPMACDGLRTICIAYRDFDDTEPSWDNENEILTELTCIA 666
KG+ + + RD + + M GLR + +A L +LT +
Sbjct: 495 SKGQTLTLTQQQRD-VYQQEKARMGSAGLRVLALA-------------SGPELGQLTFLG 540
Query: 667 VVGIEDPVRPEVPDAIAKCKQAGITVRMVTGDNINTARAIATKCGILTPGDDFLCLEGKE 726
+VGI DP R V +A+ +G++++M+TGD+ TA AIA++ G+ + + G+E
Sbjct: 541 LVGIIDPPRTGVKEAVTTLIASGVSIKMITGDSQETAVAIASRLGLYSKTSQ--SVSGEE 598
Query: 727 FNRLIRNEKGEVEQEKLDKIWPKLRVLARSSPTDKHTLVKGIIDSTVGEHRQVVAVTGDG 786
+ + + ++L +I PK+ V R+SP K ++K + ++ VVA+TGDG
Sbjct: 599 IDAM--------DVQQLSQIVPKVAVFYRASPRHKMKIIKSL-----QKNGSVVAMTGDG 645
Query: 787 TNDGPALKKADVGFAMGIAGTDVAKEASDIILTDDNFTSIVKAVMWGRNVYDSISKFLQF 846
ND ALK AD+G AMG GTDV KEA+D+IL DD+F +I+ A+ G+ +Y++I F++F
Sbjct: 646 VNDAVALKAADIGVAMGQTGTDVCKEAADMILVDDDFQTIMSAIEEGKGIYNNIKNFVRF 705
Query: 847 QLTVNVVAVIVAFTGACITQDSPLKAVQMLWVNLIMDTFASLALATEPPTESLLKRRPYG 906
QL+ ++ A+ + + +PL A+Q+LW+N+IMD + +L EP + ++++ P
Sbjct: 706 QLSTSIAALTLISLATLMNFPNPLNAMQILWINIIMDGPPAQSLGVEPVDKDVIRKPPRN 765
Query: 907 RNKPLISRTMMKNILGHAFYQLIVIFILVFAGEKFFDIDSGRKAPLHSPPSQHYTIVFNT 966
++++ ++ IL V I++ G F R+ + + T+ F
Sbjct: 766 WKDSILTKNLILKIL--------VSSIIIVCGTLFV---FWRELRDNVITPRDTTMTFTC 814
Query: 967 FVLMQLFNEINSRKIHGEKNVFS-GIYRNIIFCSVVLGTFICQIFIVEFG--GKPFSCTS 1023
FV +FN ++SR K+VF G+ N +FC VLG+ + Q+ ++ F K F S
Sbjct: 815 FVFFDMFNALSSRS--QTKSVFEIGLCSNRMFCYAVLGSIMGQLLVIYFPPLQKVFQTES 872
Query: 1024 LSLSQWLWCL 1033
LS+ L+ L
Sbjct: 873 LSILDLLFLL 882
>gi|48762685 calcium-transporting ATPase 2C1 isoform 1a [Homo sapiens]
Length = 919
Score = 290 bits (743), Expect = 4e-78
Identities = 253/910 (27%), Positives = 420/910 (46%), Gaps = 156/910 (17%)
Query: 151 EGAAILFSVIIVVLVTAFNDWSKEKQFRGLQCRIEQEQKFSIIRNGQLIQLPVAEIVVGD 210
+ +I +++IVV V ++ EK L + E +R G+L ++V GD
Sbjct: 102 DAVSITVAILIVVTVAFVQEYRSEKSLEELSKLVPPE--CHCVREGKLEHTLARDLVPGD 159
Query: 211 IAQVKYGDLLPADGILIQGNDLKIDESSLTGESDHVKKSLDKDPMLLSGTHVMEGSGRMV 270
+ GD +PAD L + DL IDESSLTGE+ K P +G + + R
Sbjct: 160 TVCLSVGDRVPADLRLFEAVDLSIDESSLTGETTPCSKVTAPQPAATNG----DLASRSN 215
Query: 271 VTAVGVNSQTGIILTLLGVNEDDEGEKKKKGKKQGVPENRNKAKTQDGVALEIQPLNSQE 330
+ +G + G K KG G EN ++ G ++
Sbjct: 216 IAFMGTLVRCG----------------KAKGVVIGTGEN-----SEFGEVFKMM------ 248
Query: 331 GIDNEEKDKKAVKVPKKEKSVLQGKLTRLAVQIGKAGLLMSALTVFILILYFVIDNFVIN 390
+ ++A K P ++ L GK G G++M
Sbjct: 249 ------QAEEAPKTPLQKSMDLLGKQLSF-YSFGIIGIIMLV------------------ 283
Query: 391 RRPWLPECTPIYIQYFVKFFIIGITVLVVAVPEGLPLAVTISLAYSVKKMMKDNNLVRHL 450
WL + ++ F I +++ V A+PEGLP+ VT++LA V +M+K +V+ L
Sbjct: 284 --GWLLG------KDILEMFTISVSLAVAAIPEGLPIVVTVTLALGVMRMVKKRAIVKKL 335
Query: 451 DACETMGNATAICSDKTGTLTMNRMTV--------VQAYIGGIHYRQIPSPDVFLPKVLD 502
ET+G ICSDKTGTLT N MTV + A + G+ Y Q +
Sbjct: 336 PIVETLGCCNVICSDKTGTLTKNEMTVTHIFTSDGLHAEVTGVGYNQFG----------E 385
Query: 503 LIVNGISINSAYTSKILPPEKEGGLPRQ--------VGNKTECALLGF-----VTDLKQD 549
+IV+G ++ Y + + G + +G TE AL+ + L+QD
Sbjct: 386 VIVDGDVVHGFYNPAVSRIVEAGCVCNDAVIRNNTLMGKPTEGALIALAMKMGLDGLQQD 445
Query: 550 YQAVRNEVPEEKLYKVYTFNSVRKSMSTVIRNPNGGFR---MYSKGASEIILRKCNRILD 606
Y +R Y F+S +K M+ + R + KGA E +++ C
Sbjct: 446 Y--IRKAE--------YPFSSEQKWMAVKCVHRTQQDRPEICFMKGAYEQVIKYCTTY-Q 494
Query: 607 RKGEAVPFKNKDRDDMVRTVIEPMACDGLRTICIAYRDFDDTEPSWDNENEILTELTCIA 666
KG+ + + RD + + M GLR + +A L +LT +
Sbjct: 495 SKGQTLTLTQQQRD-VYQQEKARMGSAGLRVLALA-------------SGPELGQLTFLG 540
Query: 667 VVGIEDPVRPEVPDAIAKCKQAGITVRMVTGDNINTARAIATKCGILTPGDDFLCLEGKE 726
+VGI DP R V +A+ +G++++M+TGD+ TA AIA++ G+ + + G+E
Sbjct: 541 LVGIIDPPRTGVKEAVTTLIASGVSIKMITGDSQETAVAIASRLGLYSKTSQ--SVSGEE 598
Query: 727 FNRLIRNEKGEVEQEKLDKIWPKLRVLARSSPTDKHTLVKGIIDSTVGEHRQVVAVTGDG 786
+ + + ++L +I PK+ V R+SP K ++K + ++ VVA+TGDG
Sbjct: 599 IDAM--------DVQQLSQIVPKVAVFYRASPRHKMKIIKSL-----QKNGSVVAMTGDG 645
Query: 787 TNDGPALKKADVGFAMGIAGTDVAKEASDIILTDDNFTSIVKAVMWGRNVYDSISKFLQF 846
ND ALK AD+G AMG GTDV KEA+D+IL DD+F +I+ A+ G+ +Y++I F++F
Sbjct: 646 VNDAVALKAADIGVAMGQTGTDVCKEAADMILVDDDFQTIMSAIEEGKGIYNNIKNFVRF 705
Query: 847 QLTVNVVAVIVAFTGACITQDSPLKAVQMLWVNLIMDTFASLALATEPPTESLLKRRPYG 906
QL+ ++ A+ + + +PL A+Q+LW+N+IMD + +L EP + ++++ P
Sbjct: 706 QLSTSIAALTLISLATLMNFPNPLNAMQILWINIIMDGPPAQSLGVEPVDKDVIRKPPRN 765
Query: 907 RNKPLISRTMMKNILGHAFYQLIVIFILVFAGEKFFDIDSGRKAPLHSPPSQHYTIVFNT 966
++++ ++ IL V I++ G F R+ + + T+ F
Sbjct: 766 WKDSILTKNLILKIL--------VSSIIIVCGTLFV---FWRELRDNVITPRDTTMTFTC 814
Query: 967 FVLMQLFNEINSRKIHGEKNVFS-GIYRNIIFCSVVLGTFICQIFIVEFG--GKPFSCTS 1023
FV +FN ++SR K+VF G+ N +FC VLG+ + Q+ ++ F K F S
Sbjct: 815 FVFFDMFNALSSRS--QTKSVFEIGLCSNRMFCYAVLGSIMGQLLVIYFPPLQKVFQTES 872
Query: 1024 LSLSQWLWCL 1033
LS+ L+ L
Sbjct: 873 LSILDLLFLL 882
>gi|48762687 calcium-transporting ATPase 2C1 isoform 1c [Homo sapiens]
Length = 888
Score = 289 bits (739), Expect = 1e-77
Identities = 251/903 (27%), Positives = 417/903 (46%), Gaps = 156/903 (17%)
Query: 151 EGAAILFSVIIVVLVTAFNDWSKEKQFRGLQCRIEQEQKFSIIRNGQLIQLPVAEIVVGD 210
+ +I +++IVV V ++ EK L + E +R G+L ++V GD
Sbjct: 102 DAVSITVAILIVVTVAFVQEYRSEKSLEELSKLVPPE--CHCVREGKLEHTLARDLVPGD 159
Query: 211 IAQVKYGDLLPADGILIQGNDLKIDESSLTGESDHVKKSLDKDPMLLSGTHVMEGSGRMV 270
+ GD +PAD L + DL IDESSLTGE+ K P +G + + R
Sbjct: 160 TVCLSVGDRVPADLRLFEAVDLSIDESSLTGETTPCSKVTAPQPAATNG----DLASRSN 215
Query: 271 VTAVGVNSQTGIILTLLGVNEDDEGEKKKKGKKQGVPENRNKAKTQDGVALEIQPLNSQE 330
+ +G + G K KG G EN ++ G ++
Sbjct: 216 IAFMGTLVRCG----------------KAKGVVIGTGEN-----SEFGEVFKMM------ 248
Query: 331 GIDNEEKDKKAVKVPKKEKSVLQGKLTRLAVQIGKAGLLMSALTVFILILYFVIDNFVIN 390
+ ++A K P ++ L GK G G++M
Sbjct: 249 ------QAEEAPKTPLQKSMDLLGKQLSF-YSFGIIGIIMLV------------------ 283
Query: 391 RRPWLPECTPIYIQYFVKFFIIGITVLVVAVPEGLPLAVTISLAYSVKKMMKDNNLVRHL 450
WL + ++ F I +++ V A+PEGLP+ VT++LA V +M+K +V+ L
Sbjct: 284 --GWLLG------KDILEMFTISVSLAVAAIPEGLPIVVTVTLALGVMRMVKKRAIVKKL 335
Query: 451 DACETMGNATAICSDKTGTLTMNRMTV--------VQAYIGGIHYRQIPSPDVFLPKVLD 502
ET+G ICSDKTGTLT N MTV + A + G+ Y Q +
Sbjct: 336 PIVETLGCCNVICSDKTGTLTKNEMTVTHIFTSDGLHAEVTGVGYNQFG----------E 385
Query: 503 LIVNGISINSAYTSKILPPEKEGGLPRQ--------VGNKTECALLGF-----VTDLKQD 549
+IV+G ++ Y + + G + +G TE AL+ + L+QD
Sbjct: 386 VIVDGDVVHGFYNPAVSRIVEAGCVCNDAVIRNNTLMGKPTEGALIALAMKMGLDGLQQD 445
Query: 550 YQAVRNEVPEEKLYKVYTFNSVRKSMSTVIRNPNGGFR---MYSKGASEIILRKCNRILD 606
Y +R Y F+S +K M+ + R + KGA E +++ C
Sbjct: 446 Y--IRKAE--------YPFSSEQKWMAVKCVHRTQQDRPEICFMKGAYEQVIKYCTTY-Q 494
Query: 607 RKGEAVPFKNKDRDDMVRTVIEPMACDGLRTICIAYRDFDDTEPSWDNENEILTELTCIA 666
KG+ + + RD + + M GLR + +A L +LT +
Sbjct: 495 SKGQTLTLTQQQRD-VYQQEKARMGSAGLRVLALA-------------SGPELGQLTFLG 540
Query: 667 VVGIEDPVRPEVPDAIAKCKQAGITVRMVTGDNINTARAIATKCGILTPGDDFLCLEGKE 726
+VGI DP R V +A+ +G++++M+TGD+ TA AIA++ G+ + + G+E
Sbjct: 541 LVGIIDPPRTGVKEAVTTLIASGVSIKMITGDSQETAVAIASRLGLYSKTSQ--SVSGEE 598
Query: 727 FNRLIRNEKGEVEQEKLDKIWPKLRVLARSSPTDKHTLVKGIIDSTVGEHRQVVAVTGDG 786
+ + + ++L +I PK+ V R+SP K ++K + ++ VVA+TGDG
Sbjct: 599 IDAM--------DVQQLSQIVPKVAVFYRASPRHKMKIIKSL-----QKNGSVVAMTGDG 645
Query: 787 TNDGPALKKADVGFAMGIAGTDVAKEASDIILTDDNFTSIVKAVMWGRNVYDSISKFLQF 846
ND ALK AD+G AMG GTDV KEA+D+IL DD+F +I+ A+ G+ +Y++I F++F
Sbjct: 646 VNDAVALKAADIGVAMGQTGTDVCKEAADMILVDDDFQTIMSAIEEGKGIYNNIKNFVRF 705
Query: 847 QLTVNVVAVIVAFTGACITQDSPLKAVQMLWVNLIMDTFASLALATEPPTESLLKRRPYG 906
QL+ ++ A+ + + +PL A+Q+LW+N+IMD + +L EP + ++++ P
Sbjct: 706 QLSTSIAALTLISLATLMNFPNPLNAMQILWINIIMDGPPAQSLGVEPVDKDVIRKPPRN 765
Query: 907 RNKPLISRTMMKNILGHAFYQLIVIFILVFAGEKFFDIDSGRKAPLHSPPSQHYTIVFNT 966
++++ ++ IL V I++ G F R+ + + T+ F
Sbjct: 766 WKDSILTKNLILKIL--------VSSIIIVCGTLFV---FWRELRDNVITPRDTTMTFTC 814
Query: 967 FVLMQLFNEINSRKIHGEKNVFS-GIYRNIIFCSVVLGTFICQIFIVEFG--GKPFSCTS 1023
FV +FN ++SR K+VF G+ N +FC VLG+ + Q+ ++ F K F S
Sbjct: 815 FVFFDMFNALSSRS--QTKSVFEIGLCSNRMFCYAVLGSIMGQLLVIYFPPLQKVFQTES 872
Query: 1024 LSL 1026
LS+
Sbjct: 873 LSI 875
>gi|209413709 ATPase, Ca++ transporting, slow twitch 2 isoform 3 [Homo
sapiens]
Length = 1015
Score = 270 bits (689), Expect = 8e-72
Identities = 288/1095 (26%), Positives = 469/1095 (42%), Gaps = 194/1095 (17%)
Query: 45 NVHYGGVQNLCSRLKTSPVEGLSGNPADLEKRRQVFGHNVIPPKKPKTFLELVWEALQDV 104
N H V+ + + GLS ++K ++ +G N +P ++ KT LELV E +D+
Sbjct: 3 NAHTKTVEEVLGHFGVNESTGLSLE--QVKKLKERWGSNELPAEEGKTLLELVIEQFEDL 60
Query: 105 TLIILEIAAIISLVLSFYRPAGEENELCGQVATTPEDENEAQAGWIEGAAILFSVIIVVL 164
+ IL +AA IS VL+++ E+ E ++E IL ++ +
Sbjct: 61 LVRILLLAACISFVLAWF-----------------EEGEETITAFVEPFVILLILVANAI 103
Query: 165 VTAFNDWSKEKQFRGLQCRIEQEQKFSIIRNGQLIQLPVAEIVVGDIAQVKYGDLLPADG 224
V + + + E L+ E E ++ + +Q ++K D++P D
Sbjct: 104 VGVWQERNAENAIEALK-EYEPEMGKVYRQDRKSVQ------------RIKAKDIVPGDI 150
Query: 225 ILIQGNDLKIDESSLTGESDHVKKSLDKDPMLLSGTHVMEGSGRMVVTAVGVNSQTGIIL 284
+ I G + + + + D + DK ML SGT++ G A+GV TG+
Sbjct: 151 VEIAGESVSVIKHT-DPVPDPRAVNQDKKNMLFSGTNIAAGK------AMGVVVATGV-- 201
Query: 285 TLLGVNEDDEGEKKKKGKKQGVPENRNKAKTQDGVALEIQPLNSQEGIDNEEKDKKAVKV 344
N++ G K + +
Sbjct: 202 ------------------------------------------NTEIG-----KIRDEMVA 214
Query: 345 PKKEKSVLQGKLTRLAVQIGKAGLLMSALTVFILILYFVIDNFVINRRPWLPECTPIYIQ 404
++E++ LQ KL Q+ K ++S + + + I+ N ++ W I+
Sbjct: 215 TEQERTPLQQKLDEFGEQLSK---VISLICIAVWIINIGHFNDPVHGGSW--------IR 263
Query: 405 YFVKFFIIGITVLVVAVPEGLPLAVTISLAYSVKKMMKDNNLVRHLDACETMGNATAICS 464
+ +F I + + V A+PEGLP +T LA ++M K N +VR L + ET+G + ICS
Sbjct: 264 GAIYYFKIAVALAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICS 323
Query: 465 DKTGTLTMNRMTVVQAYI------------------------GGIHYRQIPSPDVFLPKV 500
DKTGTLT N+M+V + +I G +H P
Sbjct: 324 DKTGTLTTNQMSVCRMFILDRVEGDTCSLNEFTITGSTYAPIGEVHKDDKPVNC----HQ 379
Query: 501 LDLIVNGISINSAYTSKILPPEKEGGLPRQVGNKTECALLGFV-------TDLKQDYQAV 553
D +V +I + L + G+ +VG TE AL V T+LK +
Sbjct: 380 YDGLVELATICALCNDSALDYNEAKGVYEKVGEATETALTCLVEKMNVFDTELKGLSKIE 439
Query: 554 R----NEVPEEKLYKVYT--FNSVRKSMSTVIRNPNGGFR-----MYSKGASEIILRKCN 602
R N V ++ + K +T F+ RKSMS V PN R M+ KGA E ++ +C
Sbjct: 440 RANACNSVIKQLMKKEFTLEFSRDRKSMS-VYCTPNKPSRTSMSKMFVKGAPEGVIDRCT 498
Query: 603 RILDRKGEA-VPFKNKDRDDMVRTVIE-PMACDGLRTICIAYRDFDDTEPSW---DNENE 657
I R G VP + + ++ + E D LR + +A D D+ N
Sbjct: 499 HI--RVGSTKVPMTSGVKQKIMSVIREWGSGSDTLRCLALATHDNPLRREEMHLEDSANF 556
Query: 658 IL--TELTCIAVVGIEDPVRPEVPDAIAKCKQAGITVRMVTGDNINTARAIATKCGILTP 715
I T LT + VG+ DP R EV ++ C+QAGI V M+TGDN TA AI + GI
Sbjct: 557 IKYETNLTFVGCVGMLDPPRIEVASSVKLCRQAGIRVIMITGDNKGTAVAICRRIGIFGQ 616
Query: 716 GDDFL--CLEGKEFNRLIRNEKGEVEQEKLDKIWPKLRVLARSSPTDKHTLVKGIIDSTV 773
+D G+EF+ L + + + R AR P+ K +V+ +
Sbjct: 617 DEDVTSKAFTGREFDELNPSAQRDA--------CLNARCFARVEPSHKSKIVEFL----- 663
Query: 774 GEHRQVVAVTGDGTNDGPALKKADVGFAMGIAGTDVAKEASDIILTDDNFTSIVKAVMWG 833
++ A+TGDG ND PALKKA++G AMG +GT VAK AS+++L DDNF++IV AV G
Sbjct: 664 QSFDEITAMTGDGVNDAPALKKAEIGIAMG-SGTAVAKTASEMVLADDNFSTIVAAVEEG 722
Query: 834 RNVYDSISKFLQFQLTVNVVAVIVAFTGACITQDSPLKAVQMLWVNLIMDTFASLALATE 893
R +Y+++ +F+++ ++ NV V+ F A + L VQ+LWVNL+ D + AL
Sbjct: 723 RAIYNNMKQFIRYLISSNVGEVVCIFLTAALGFPEALIPVQLLWVNLVTDGLPATALGFN 782
Query: 894 PPTESLLKRRPYGRNKPLISRTMMKNILGHAFYQLIVI-------FILVFAGEK--FFDI 944
PP ++ + P +PLIS + L Y FI G + F+ +
Sbjct: 783 PPDLDIMNKPPRNPKEPLISGWLFFRYLAIGCYVGAATVGAAAWWFIAADGGPRVSFYQL 842
Query: 945 DSGRKAPLHSPPSQ-----------HYTIVFNTFVLMQLFNEINSRKIHGEKNVFSGIYR 993
+ +P + T+ + V +++ N +NS + + +
Sbjct: 843 SHFLQCKEDNPDFEGVDCAIFESPYPMTMALSVLVTIEMCNALNSLS-ENQSLLRMPPWE 901
Query: 994 NIIFCSVVLGTFICQIFIVEFGGKP--FSCTSLSLSQWLWCLFIGIGELLWGQFISAIPT 1051
NI + + I+ P F T L+++QWL L I + +L + + +
Sbjct: 902 NIWLVGSICLSMSLHFLILYVEPLPLIFQITPLNVTQWLMVLKISLPVILMDETLKFVAR 961
Query: 1052 RSLKFLKEAGHGTTK 1066
L+ KE TK
Sbjct: 962 NYLEPGKECVQPATK 976
>gi|83700225 hydrogen/potassium-exchanging ATPase 12A [Homo sapiens]
Length = 1039
Score = 246 bits (628), Expect = 9e-65
Identities = 231/798 (28%), Positives = 371/798 (46%), Gaps = 143/798 (17%)
Query: 161 IVVLVTAFNDWSKEKQFRGLQCRIEQ--EQKFSIIRNGQLIQLPVAEIVVGDIAQVKYGD 218
+VV++T + +E + + + Q+ +IR+ + +P ++VVGDI +VK GD
Sbjct: 153 LVVILTGIFAYYQEAKSTNIMSSFNKMIPQQALVIRDSEKKTIPSEQLVVGDIVEVKGGD 212
Query: 219 -------LLPADGILIQGNDLKIDESSLTGESDHVKKS-LDKDPMLLSGTHVMEGSGRMV 270
+L + G + + L + S+ ++ L+ + T +EG+
Sbjct: 213 QIPADIRVLSSQGCRVDNSSLTGESEPQPRSSEFTHENPLETKNICFYSTTCLEGT---- 268
Query: 271 VTAVGVNSQTGIILTLLGVNEDDEGEKKKKGKKQGVPENRNKAKTQDGVALEIQPLNSQE 330
VT + +N+ T++G I L S
Sbjct: 269 VTGMVINTGDR---TIIG---------------------------------HIASLAS-- 290
Query: 331 GIDNEEKDKKAVKVPKKEKSVLQGKLTRLAVQIGKAGLLMSALTVFILILYFVIDNFVIN 390
G+ NE+ T +A++I +++ + V I IL+F+I
Sbjct: 291 GVGNEK--------------------TPIAIEIEHFVHIVAGVAVSIGILFFII------ 324
Query: 391 RRPWLPECTPIYIQYFVKFFIIGITVLVVA-VPEGLPLAVTISLAYSVKKMMKDNNLVRH 449
+ ++Y V II + ++VA VPEGL VT++L+ + K+M K N LV++
Sbjct: 325 ---------AVSLKYQVLDSIIFLIGIIVANVPEGLLATVTVTLSLTAKRMAKKNCLVKN 375
Query: 450 LDACETMGNATAICSDKTGTLTMNRMTVVQAYIGGIHYRQIPSPDVFLPKVLDLIVNGIS 509
L+A ET+G+ + ICSDKTGTLT NRMTV + + S D + + + S
Sbjct: 376 LEAVETLGSTSIICSDKTGTLTQNRMTVAHLWFDNQIFVADTSEDHS-----NQVFDQSS 430
Query: 510 INSAYTSKIL---------PPEKEGGLPRQ--VGNKTECALLGFVTDLKQDYQAVRNEVP 558
A SKI+ P ++ + ++ +G+ +E ALL F + D +R
Sbjct: 431 RTWASLSKIITLCNRAEFKPGQENVPIMKKAVIGDASETALLKFSEVILGDVMEIRKR-- 488
Query: 559 EEKLYKVYTFNSVRKSMSTV--IRNPNGG-FRMYSKGASEIILRKCNRILDRKGEAVPFK 615
K+ ++ FNS K ++ + +P+G F M KGA E IL KC+ I+ GE P
Sbjct: 489 NRKVAEI-PFNSTNKFQLSIHEMDDPHGKRFLMVMKGAPERILEKCSTIMIN-GEEHPL- 545
Query: 616 NKDRDDMVRTVIEPMACDGLRTI--CIAYRDFDDTEPSW----DNENEILTELTCIAVVG 669
+K T + G R + C Y D+ ++ D N + L + ++
Sbjct: 546 DKSTAKTFHTAYMELGGLGERVLGFCHLYLPADEFPETYSFDIDAMNFPTSNLCFVGLLS 605
Query: 670 IEDPVRPEVPDAIAKCKQAGITVRMVTGDNINTARAIATKCGILTPGDDFLCLEGKEFNR 729
+ DP R VPDA+ KC+ AGI V MVTGD+ TA+AIA GI++ + + N
Sbjct: 606 MIDPPRSTVPDAVTKCRSAGIKVIMVTGDHPITAKAIAKSVGIISANSETVEDIAHRLNI 665
Query: 730 LIRN--------------EKGEVEQEKLDKIWPKLR--VLARSSPTDKHTLVKGIIDSTV 773
+ E ++ E+LD+I + V AR+SP K +V+G
Sbjct: 666 AVEQVNKRDAKAAVVTGMELKDMSSEQLDEILANYQEIVFARTSPQQKLIIVEGC----- 720
Query: 774 GEHRQ--VVAVTGDGTNDGPALKKADVGFAMGIAGTDVAKEASDIILTDDNFTSIVKAVM 831
RQ VVAVTGDG ND PALKKAD+G AMGIAG+D AK A+D++L DDNF SIV V
Sbjct: 721 --QRQDAVVAVTGDGVNDSPALKKADIGIAMGIAGSDAAKNAADMVLLDDNFASIVTGVE 778
Query: 832 WGRNVYDSISKFLQFQLTVNVVAVIVAFTGACITQDSPLKAVQMLWVNLIMDTFASLALA 891
GR ++D++ K + + LT N+ + + P+ + +L+++L D S+ALA
Sbjct: 779 EGRLIFDNLKKTIAYSLTKNIAELCPFLIYIIVGLPLPIGTITILFIDLGTDIIPSIALA 838
Query: 892 TEPPTESLLKRRPYGRNK 909
E ++ R+P +NK
Sbjct: 839 YEKAESDIMNRKPRHKNK 856
>gi|118498343 ATPase, Ca++ transporting, type 2C, member 2 [Homo
sapiens]
Length = 946
Score = 243 bits (620), Expect = 8e-64
Identities = 190/627 (30%), Positives = 309/627 (49%), Gaps = 78/627 (12%)
Query: 407 VKFFIIGITVLVVAVPEGLPLAVTISLAYSVKKMMKDNNLVRHLDACETMGNATAICSDK 466
+ F IG+++ V A+PEGLP+ V ++L V +M K +V+ L ET+G + +CSDK
Sbjct: 321 LSMFTIGVSLAVAAIPEGLPIVVMVTLVLGVLRMAKKRVIVKKLPIVETLGCCSVLCSDK 380
Query: 467 TGTLTMNRMTVVQ--------AYIGGIHYRQ------IPSPDVFLP----KVLDLIVNGI 508
TGTLT N MTV Q A + G+ Y +PS +V V L+ G
Sbjct: 381 TGTLTANEMTVTQLVTSDGLRAEVSGVGYDGQGTVCLLPSKEVIKEFSNVSVGKLVEAGC 440
Query: 509 SINSAYTSKILPPEKEGGLPRQVGNKTECALLGFVTDLKQDYQAVRNEVPEEKLYKVYTF 568
N+A K +G TE AL+ +K D ++N +K F
Sbjct: 441 VANNAVIRK----------NAVMGQPTEGALMALA--MKMDLSDIKNSYIRKK---EIPF 485
Query: 569 NSVRKSMSTV--IRNPNGGFRMYSKGASEIILRKCNRILDRKGEAVPFKNKDRDDMVRTV 626
+S +K M+ ++ + + KGA E ++R C + + G +P + R ++
Sbjct: 486 SSEQKWMAVKCSLKTEDQEDIYFMKGALEEVIRYCT-MYNNGGIPLPLTPQQRSFCLQEE 544
Query: 627 IEPMACDGLRTICIAYRDFDDTEPSWDNENEILTELTCIAVVGIEDPVRPEVPDAIAKCK 686
+ M GLR + +A L LT + +VGI DP R V +A+
Sbjct: 545 -KRMGSLGLRVLALA-------------SGPELGRLTFLGLVGIIDPPRVGVKEAVQVLS 590
Query: 687 QAGITVRMVTGDNINTARAIATKCGILTPGDDFLCLEGKEFNRLIRNEKGEVEQEKLDKI 746
++G++V+M+TGD + TA AI G+ + G+E + + EKGE+ D++
Sbjct: 591 ESGVSVKMITGDALETALAIGRNIGLCN--GKLQAMSGEEVDSV---EKGELA----DRV 641
Query: 747 WPKLRVLARSSPTDKHTLVKGIIDSTVGEHRQVVAVTGDGTNDGPALKKADVGFAMGIAG 806
K+ V R+SP K ++K + +S +VA+TGDG ND ALK AD+G AMG G
Sbjct: 642 G-KVSVFFRTSPKHKLKIIKALQESGA-----IVAMTGDGVNDAVALKSADIGIAMGQTG 695
Query: 807 TDVAKEASDIILTDDNFTSIVKAVMWGRNVYDSISKFLQFQLTVNVVAVIVAFTGACITQ 866
TDV+KEA+++IL DD+F++I+ AV G+ ++ +I F++FQL+ ++ A+ +
Sbjct: 696 TDVSKEAANMILVDDDFSAIMNAVEEGKGIFYNIKNFVRFQLSTSISALSLITLSTVFNL 755
Query: 867 DSPLKAVQMLWVNLIMDTFASLALATEPPTESLLKRRPYGRNKPLISRTMMKNILGHAFY 926
SPL A+Q+LW+N+IMD + +L EP + ++ P ++SR ++ IL A
Sbjct: 756 PSPLNAMQILWINIIMDGPPAQSLGVEPVDKDAFRQPPRSVRDTILSRALILKILMSA-- 813
Query: 927 QLIVIFILVFAGEKFFDIDSGRKAPLHSPPSQHYTIVFNTFVLMQLFNEINSRKIHGEKN 986
++ +G F + +P + T+ F FV LFN + R K
Sbjct: 814 ------AIIISGTLFIFWKEMPEDRASTPRTT--TMTFTCFVFFDLFNALTCRS--QTKL 863
Query: 987 VFS-GIYRNIIFCSVVLGTFICQIFIV 1012
+F G RN +F VLG+ + Q+ ++
Sbjct: 864 IFEIGFLRNHMFLYSVLGSILGQLAVI 890
Score = 68.2 bits (165), Expect = 4e-11
Identities = 47/165 (28%), Positives = 77/165 (46%), Gaps = 12/165 (7%)
Query: 151 EGAAILFSVIIVVLVTAFNDWSKEKQFRGLQCRIEQEQKFSIIRNGQLIQLPVAEIVVGD 210
+ +I +V++VV V ++ EK L + E + +R G+L L E+V GD
Sbjct: 133 DAVSIATAVLVVVTVAFIQEYRSEKSLEELTKMVPPE--CNCLREGKLQHLLARELVPGD 190
Query: 211 IAQVKYGDLLPADGILIQGNDLKIDESSLTGESDHVKKS----------LDKDPMLLSGT 260
+ + GD +PAD L + DL +DESS TGE++ K+ ++ GT
Sbjct: 191 VVSLSIGDRIPADIRLTEVTDLLVDESSFTGEAEPCSKTDSPLTGGGDLTTLSNIVFMGT 250
Query: 261 HVMEGSGRMVVTAVGVNSQTGIILTLLGVNEDDEGEKKKKGKKQG 305
V G G+ VV G +SQ G + ++ E + +K + G
Sbjct: 251 LVQYGRGQGVVIGTGESSQFGEVFKMMQAEETPKTPLQKSMDRLG 295
>gi|237681109 Na+/K+ -ATPase alpha 1 subunit isoform c [Homo
sapiens]
Length = 1023
Score = 237 bits (605), Expect = 4e-62
Identities = 192/622 (30%), Positives = 303/622 (48%), Gaps = 76/622 (12%)
Query: 350 SVLQGKLTRLAVQIGKAGLLMSALTVFILILYFVIDNFVINRRPWLPECTPIYIQYFVKF 409
S L+G T +A +I +++ + VF+ + +F++ +I WL
Sbjct: 275 SGLEGGQTPIAAEIEHFIHIITGVAVFLGVSFFILS--LILEYTWLEAV----------I 322
Query: 410 FIIGITVLVVAVPEGLPLAVTISLAYSVKKMMKDNNLVRHLDACETMGNATAICSDKTGT 469
F+IGI +V VPEGL VT+ L + K+M + N LV++L+A ET+G+ + ICSDKTGT
Sbjct: 323 FLIGI--IVANVPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGT 380
Query: 470 LTMNRMTVVQAYI-------------GGIHYRQIPSPDVFLPKVLDLIVNGISINSAYTS 516
LT NRMTV + G+ + + + + L ++ L + +
Sbjct: 381 LTQNRMTVAHMWFDNQIHEADTTENQSGVSFDKTSATWLALSRIAGLCNRAVFQANQENL 440
Query: 517 KILPPEKEGGLPRQVGNKTECALLGFVTDLKQDYQAVRNEVPEEKLYKVYTFNSVRKSMS 576
IL G K G V ++++ Y + E+P FNS K
Sbjct: 441 PILKRAVAGDASESALLKCIELCCGSVKEMRERYAKIV-EIP---------FNSTNKYQL 490
Query: 577 TVIRNPNGG---FRMYSKGASEIILRKCNRILDRKGEAVPFKNKDRDDMVRTVIEPMACD 633
++ +NPN + KGA E IL +C+ IL G+ P + +D +E +
Sbjct: 491 SIHKNPNTSEPQHLLVMKGAPERILDRCSSIL-LHGKEQPLDEELKDAFQNAYLE-LGGL 548
Query: 634 GLRTICIAYRDFDDTEP------SWDNENEILTELTCIAVVGIEDPVRPEVPDAIAKCKQ 687
G R + + D + D+ N + L + ++ + DP R VPDA+ KC+
Sbjct: 549 GERVLGFCHLFLPDEQFPEGFQFDTDDVNFPIDNLCFVGLISMIDPPRAAVPDAVGKCRS 608
Query: 688 AGITVRMVTGDNINTARAIATKCGILTPGDDFLCLEGKEFNRLI-----RNEKG------ 736
AGI V MVTGD+ TA+AIA GI++ G++ + N + R+ K
Sbjct: 609 AGIKVIMVTGDHPITAKAIAKGVGIISEGNETVEDIAARLNIPVSQVNPRDAKACVVHGS 668
Query: 737 ---EVEQEKLDKI--WPKLRVLARSSPTDKHTLVKGIIDSTVGEHRQ--VVAVTGDGTND 789
++ E+LD I + V AR+SP K +V+G RQ +VAVTGDG ND
Sbjct: 669 DLKDMTSEQLDDILKYHTEIVFARTSPQQKLIIVEGC-------QRQGAIVAVTGDGVND 721
Query: 790 GPALKKADVGFAMGIAGTDVAKEASDIILTDDNFTSIVKAVMWGRNVYDSISKFLQFQLT 849
PALKKAD+G AMGIAG+DV+K+A+D+IL DDNF SIV V GR ++D++ K + + LT
Sbjct: 722 SPALKKADIGVAMGIAGSDVSKQAADMILLDDNFASIVTGVEEGRLIFDNLKKSIAYTLT 781
Query: 850 VNVVAVIVAFTGACITQDSPLKAVQMLWVNLIMDTFASLALATEPPTESLLKRRPYGRNK 909
N+ + PL V +L ++L D +++LA E ++KR+P
Sbjct: 782 SNIPEITPFLIFIIANIPLPLGTVTILCIDLGTDMVPAISLAYEQAESDIMKRQP---RN 838
Query: 910 PLISRTMMKNILGHAFYQLIVI 931
P + + + ++ A+ Q+ +I
Sbjct: 839 PKTDKLVNERLISMAYGQIGMI 860
Score = 71.2 bits (173), Expect = 5e-12
Identities = 51/161 (31%), Positives = 80/161 (49%), Gaps = 13/161 (8%)
Query: 134 QVATTPEDENEAQAGWIEGAAILFSVIIVVLVTAFNDWSKEKQFRGLQCRIEQEQKFSII 193
Q AT E +N+ G + VII + + + K + + Q+ +I
Sbjct: 118 QAATEEEPQND---NLYLGVVLSAVVIITGCFSYYQEAKSSKIMESFKNMVPQQAL--VI 172
Query: 194 RNGQLIQLPVAEIVVGDIAQVKYGDLLPADGILIQGNDLKIDESSLTGESDHVKKSLD-- 251
RNG+ + + E+VVGD+ +VK GD +PAD +I N K+D SSLTGES+ +S D
Sbjct: 173 RNGEKMSINAEEVVVGDLVEVKGGDRIPADLRIISANGCKVDNSSLTGESEPQTRSPDFT 232
Query: 252 -KDPM-----LLSGTHVMEGSGRMVVTAVGVNSQTGIILTL 286
++P+ T+ +EG+ R +V G + G I TL
Sbjct: 233 NENPLETRNIAFFSTNCVEGTARGIVVYTGDRTVMGRIATL 273
>gi|237681111 Na+/K+ -ATPase alpha 1 subunit isoform d [Homo
sapiens]
Length = 992
Score = 237 bits (605), Expect = 4e-62
Identities = 192/622 (30%), Positives = 303/622 (48%), Gaps = 76/622 (12%)
Query: 350 SVLQGKLTRLAVQIGKAGLLMSALTVFILILYFVIDNFVINRRPWLPECTPIYIQYFVKF 409
S L+G T +A +I +++ + VF+ + +F++ +I WL
Sbjct: 244 SGLEGGQTPIAAEIEHFIHIITGVAVFLGVSFFILS--LILEYTWLEAV----------I 291
Query: 410 FIIGITVLVVAVPEGLPLAVTISLAYSVKKMMKDNNLVRHLDACETMGNATAICSDKTGT 469
F+IGI +V VPEGL VT+ L + K+M + N LV++L+A ET+G+ + ICSDKTGT
Sbjct: 292 FLIGI--IVANVPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGT 349
Query: 470 LTMNRMTVVQAYI-------------GGIHYRQIPSPDVFLPKVLDLIVNGISINSAYTS 516
LT NRMTV + G+ + + + + L ++ L + +
Sbjct: 350 LTQNRMTVAHMWFDNQIHEADTTENQSGVSFDKTSATWLALSRIAGLCNRAVFQANQENL 409
Query: 517 KILPPEKEGGLPRQVGNKTECALLGFVTDLKQDYQAVRNEVPEEKLYKVYTFNSVRKSMS 576
IL G K G V ++++ Y + E+P FNS K
Sbjct: 410 PILKRAVAGDASESALLKCIELCCGSVKEMRERYAKIV-EIP---------FNSTNKYQL 459
Query: 577 TVIRNPNGG---FRMYSKGASEIILRKCNRILDRKGEAVPFKNKDRDDMVRTVIEPMACD 633
++ +NPN + KGA E IL +C+ IL G+ P + +D +E +
Sbjct: 460 SIHKNPNTSEPQHLLVMKGAPERILDRCSSIL-LHGKEQPLDEELKDAFQNAYLE-LGGL 517
Query: 634 GLRTICIAYRDFDDTEP------SWDNENEILTELTCIAVVGIEDPVRPEVPDAIAKCKQ 687
G R + + D + D+ N + L + ++ + DP R VPDA+ KC+
Sbjct: 518 GERVLGFCHLFLPDEQFPEGFQFDTDDVNFPIDNLCFVGLISMIDPPRAAVPDAVGKCRS 577
Query: 688 AGITVRMVTGDNINTARAIATKCGILTPGDDFLCLEGKEFNRLI-----RNEKG------ 736
AGI V MVTGD+ TA+AIA GI++ G++ + N + R+ K
Sbjct: 578 AGIKVIMVTGDHPITAKAIAKGVGIISEGNETVEDIAARLNIPVSQVNPRDAKACVVHGS 637
Query: 737 ---EVEQEKLDKI--WPKLRVLARSSPTDKHTLVKGIIDSTVGEHRQ--VVAVTGDGTND 789
++ E+LD I + V AR+SP K +V+G RQ +VAVTGDG ND
Sbjct: 638 DLKDMTSEQLDDILKYHTEIVFARTSPQQKLIIVEGC-------QRQGAIVAVTGDGVND 690
Query: 790 GPALKKADVGFAMGIAGTDVAKEASDIILTDDNFTSIVKAVMWGRNVYDSISKFLQFQLT 849
PALKKAD+G AMGIAG+DV+K+A+D+IL DDNF SIV V GR ++D++ K + + LT
Sbjct: 691 SPALKKADIGVAMGIAGSDVSKQAADMILLDDNFASIVTGVEEGRLIFDNLKKSIAYTLT 750
Query: 850 VNVVAVIVAFTGACITQDSPLKAVQMLWVNLIMDTFASLALATEPPTESLLKRRPYGRNK 909
N+ + PL V +L ++L D +++LA E ++KR+P
Sbjct: 751 SNIPEITPFLIFIIANIPLPLGTVTILCIDLGTDMVPAISLAYEQAESDIMKRQP---RN 807
Query: 910 PLISRTMMKNILGHAFYQLIVI 931
P + + + ++ A+ Q+ +I
Sbjct: 808 PKTDKLVNERLISMAYGQIGMI 829
Score = 71.2 bits (173), Expect = 5e-12
Identities = 51/161 (31%), Positives = 80/161 (49%), Gaps = 13/161 (8%)
Query: 134 QVATTPEDENEAQAGWIEGAAILFSVIIVVLVTAFNDWSKEKQFRGLQCRIEQEQKFSII 193
Q AT E +N+ G + VII + + + K + + Q+ +I
Sbjct: 87 QAATEEEPQND---NLYLGVVLSAVVIITGCFSYYQEAKSSKIMESFKNMVPQQAL--VI 141
Query: 194 RNGQLIQLPVAEIVVGDIAQVKYGDLLPADGILIQGNDLKIDESSLTGESDHVKKSLD-- 251
RNG+ + + E+VVGD+ +VK GD +PAD +I N K+D SSLTGES+ +S D
Sbjct: 142 RNGEKMSINAEEVVVGDLVEVKGGDRIPADLRIISANGCKVDNSSLTGESEPQTRSPDFT 201
Query: 252 -KDPM-----LLSGTHVMEGSGRMVVTAVGVNSQTGIILTL 286
++P+ T+ +EG+ R +V G + G I TL
Sbjct: 202 NENPLETRNIAFFSTNCVEGTARGIVVYTGDRTVMGRIATL 242
>gi|21361181 Na+/K+ -ATPase alpha 1 subunit isoform a [Homo sapiens]
Length = 1023
Score = 237 bits (605), Expect = 4e-62
Identities = 192/622 (30%), Positives = 303/622 (48%), Gaps = 76/622 (12%)
Query: 350 SVLQGKLTRLAVQIGKAGLLMSALTVFILILYFVIDNFVINRRPWLPECTPIYIQYFVKF 409
S L+G T +A +I +++ + VF+ + +F++ +I WL
Sbjct: 275 SGLEGGQTPIAAEIEHFIHIITGVAVFLGVSFFILS--LILEYTWLEAV----------I 322
Query: 410 FIIGITVLVVAVPEGLPLAVTISLAYSVKKMMKDNNLVRHLDACETMGNATAICSDKTGT 469
F+IGI +V VPEGL VT+ L + K+M + N LV++L+A ET+G+ + ICSDKTGT
Sbjct: 323 FLIGI--IVANVPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGT 380
Query: 470 LTMNRMTVVQAYI-------------GGIHYRQIPSPDVFLPKVLDLIVNGISINSAYTS 516
LT NRMTV + G+ + + + + L ++ L + +
Sbjct: 381 LTQNRMTVAHMWFDNQIHEADTTENQSGVSFDKTSATWLALSRIAGLCNRAVFQANQENL 440
Query: 517 KILPPEKEGGLPRQVGNKTECALLGFVTDLKQDYQAVRNEVPEEKLYKVYTFNSVRKSMS 576
IL G K G V ++++ Y + E+P FNS K
Sbjct: 441 PILKRAVAGDASESALLKCIELCCGSVKEMRERYAKIV-EIP---------FNSTNKYQL 490
Query: 577 TVIRNPNGG---FRMYSKGASEIILRKCNRILDRKGEAVPFKNKDRDDMVRTVIEPMACD 633
++ +NPN + KGA E IL +C+ IL G+ P + +D +E +
Sbjct: 491 SIHKNPNTSEPQHLLVMKGAPERILDRCSSIL-LHGKEQPLDEELKDAFQNAYLE-LGGL 548
Query: 634 GLRTICIAYRDFDDTEP------SWDNENEILTELTCIAVVGIEDPVRPEVPDAIAKCKQ 687
G R + + D + D+ N + L + ++ + DP R VPDA+ KC+
Sbjct: 549 GERVLGFCHLFLPDEQFPEGFQFDTDDVNFPIDNLCFVGLISMIDPPRAAVPDAVGKCRS 608
Query: 688 AGITVRMVTGDNINTARAIATKCGILTPGDDFLCLEGKEFNRLI-----RNEKG------ 736
AGI V MVTGD+ TA+AIA GI++ G++ + N + R+ K
Sbjct: 609 AGIKVIMVTGDHPITAKAIAKGVGIISEGNETVEDIAARLNIPVSQVNPRDAKACVVHGS 668
Query: 737 ---EVEQEKLDKI--WPKLRVLARSSPTDKHTLVKGIIDSTVGEHRQ--VVAVTGDGTND 789
++ E+LD I + V AR+SP K +V+G RQ +VAVTGDG ND
Sbjct: 669 DLKDMTSEQLDDILKYHTEIVFARTSPQQKLIIVEGC-------QRQGAIVAVTGDGVND 721
Query: 790 GPALKKADVGFAMGIAGTDVAKEASDIILTDDNFTSIVKAVMWGRNVYDSISKFLQFQLT 849
PALKKAD+G AMGIAG+DV+K+A+D+IL DDNF SIV V GR ++D++ K + + LT
Sbjct: 722 SPALKKADIGVAMGIAGSDVSKQAADMILLDDNFASIVTGVEEGRLIFDNLKKSIAYTLT 781
Query: 850 VNVVAVIVAFTGACITQDSPLKAVQMLWVNLIMDTFASLALATEPPTESLLKRRPYGRNK 909
N+ + PL V +L ++L D +++LA E ++KR+P
Sbjct: 782 SNIPEITPFLIFIIANIPLPLGTVTILCIDLGTDMVPAISLAYEQAESDIMKRQP---RN 838
Query: 910 PLISRTMMKNILGHAFYQLIVI 931
P + + + ++ A+ Q+ +I
Sbjct: 839 PKTDKLVNERLISMAYGQIGMI 860
Score = 71.2 bits (173), Expect = 5e-12
Identities = 51/161 (31%), Positives = 80/161 (49%), Gaps = 13/161 (8%)
Query: 134 QVATTPEDENEAQAGWIEGAAILFSVIIVVLVTAFNDWSKEKQFRGLQCRIEQEQKFSII 193
Q AT E +N+ G + VII + + + K + + Q+ +I
Sbjct: 118 QAATEEEPQND---NLYLGVVLSAVVIITGCFSYYQEAKSSKIMESFKNMVPQQAL--VI 172
Query: 194 RNGQLIQLPVAEIVVGDIAQVKYGDLLPADGILIQGNDLKIDESSLTGESDHVKKSLD-- 251
RNG+ + + E+VVGD+ +VK GD +PAD +I N K+D SSLTGES+ +S D
Sbjct: 173 RNGEKMSINAEEVVVGDLVEVKGGDRIPADLRIISANGCKVDNSSLTGESEPQTRSPDFT 232
Query: 252 -KDPM-----LLSGTHVMEGSGRMVVTAVGVNSQTGIILTL 286
++P+ T+ +EG+ R +V G + G I TL
Sbjct: 233 NENPLETRNIAFFSTNCVEGTARGIVVYTGDRTVMGRIATL 273
>gi|153946397 Na+/K+ -ATPase alpha 4 subunit isoform 1 [Homo
sapiens]
Length = 1029
Score = 225 bits (574), Expect = 2e-58
Identities = 186/611 (30%), Positives = 300/611 (49%), Gaps = 70/611 (11%)
Query: 357 TRLAVQIGKAGLLMSALTVFILILYFVIDNFVINRRPWLPECTPIYIQYFVKFFIIGITV 416
T +A +I L++ + VF+ + +F + ++ WL F+IGI
Sbjct: 290 TPIAAEIEHFIHLITVVAVFLGVTFFALS--LLLGYGWLEAI----------IFLIGI-- 335
Query: 417 LVVAVPEGLPLAVTISLAYSVKKMMKDNNLVRHLDACETMGNATAICSDKTGTLTMNRMT 476
+V VPEGL VT+ L + K+M + N LV++L+A ET+G+ + ICSDKTGTLT NRMT
Sbjct: 336 IVANVPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRMT 395
Query: 477 VVQAYIGGIHYRQIPSPDV------------FLPKVLDLIVNGISINSAYTSKILPPEKE 524
V + Y + + F+ + + N + +ILP K
Sbjct: 396 VAHMWFDMTVYEADTTEEQTGKTFTKSSDTWFMLARIAGLCNRADFKA--NQEILPIAKR 453
Query: 525 GGLPRQVGNKTECALLGFVTDLKQDYQAVRNEVPEEKLYKVYTFNSVRK-SMSTVIRNPN 583
G+ +E ALL F+ +Q Y +V + FNS K MS +R +
Sbjct: 454 A----TTGDASESALLKFI---EQSYSSVAEMREKNPKVAEIPFNSTNKYQMSIHLREDS 506
Query: 584 GGFR-MYSKGASEIILRKCNRILDRKGEAVPFKNKDRDDMVRTVIEPMACDGLRTICIAY 642
+ KGA E IL C+ L G+ ++ ++ +E + G R + +
Sbjct: 507 SQTHVLMMKGAPERILEFCSTFL-LNGQEYSMNDEMKEAFQNAYLE-LGGLGERVLGFCF 564
Query: 643 RDFDDTEP-----SWDNENEILTELTCIAVVGIEDPVRPEVPDAIAKCKQAGITVRMVTG 697
+ + + D N + L + ++ + DP R VPDA++KC+ AGI V MVTG
Sbjct: 565 LNLPSSFSKGFPFNTDEINFPMDNLCFVGLISMIDPPRAAVPDAVSKCRSAGIKVIMVTG 624
Query: 698 DNINTARAIATKCGILTPGDD------------FLCLEGKEFNRLIRN--EKGEVEQEKL 743
D+ TA+AIA GI++ G + ++ ++ + E +++ ++L
Sbjct: 625 DHPITAKAIAKGVGIISEGTETAEEVAARLKIPISKVDASAAKAIVVHGAELKDIQSKQL 684
Query: 744 DKIW---PKLRVLARSSPTDKHTLVKGIIDSTVGEHRQVVAVTGDGTNDGPALKKADVGF 800
D+I P++ V AR+SP K +V+G +G VVAVTGDG ND PALKKAD+G
Sbjct: 685 DQILQNHPEI-VFARTSPQQKLIIVEGC--QRLGA---VVAVTGDGVNDSPALKKADIGI 738
Query: 801 AMGIAGTDVAKEASDIILTDDNFTSIVKAVMWGRNVYDSISKFLQFQLTVNVVAVIVAFT 860
AMGI+G+DV+K+A+D+IL DDNF SIV V GR ++D++ K + + LT N+ +
Sbjct: 739 AMGISGSDVSKQAADMILLDDNFASIVTGVEEGRLIFDNLKKSIMYTLTSNIPEITPFLM 798
Query: 861 GACITQDSPLKAVQMLWVNLIMDTFASLALATEPPTESLLKRRPYGRNKPLISRTMMKNI 920
+ PL + +L ++L D +++LA E ++KR P P + +
Sbjct: 799 FIILGIPLPLGTITILCIDLGTDMVPAISLAYESAESDIMKRLP---RNPKTDNLVNHRL 855
Query: 921 LGHAFYQLIVI 931
+G A+ Q+ +I
Sbjct: 856 IGMAYGQIGMI 866
Score = 69.7 bits (169), Expect = 2e-11
Identities = 46/142 (32%), Positives = 82/142 (57%), Gaps = 10/142 (7%)
Query: 154 AILFSVIIVVLVTAFNDWSKEKQFRGLQC-RIEQEQKFSIIRNGQLIQLPVAEIVVGDIA 212
+I+ SV+++V F+ + + K + ++ + Q+ +IR G+ +Q+ V E+V+GD+
Sbjct: 141 SIVLSVVVIV-TGCFSYYQEAKSSKIMESFKNMVPQQALVIRGGEKMQINVQEVVLGDLV 199
Query: 213 QVKYGDLLPADGILIQGNDLKIDESSLTGESDHVKKSLD---KDPM-----LLSGTHVME 264
++K GD +PAD LI K+D SSLTGES+ +S D ++P+ T+ +E
Sbjct: 200 EIKGGDRVPADLRLISAQGCKVDNSSLTGESEPQSRSPDFTHENPLETRNICFFSTNCVE 259
Query: 265 GSGRMVVTAVGVNSQTGIILTL 286
G+ R +V A G ++ G I +L
Sbjct: 260 GTARGIVIATGDSTVMGRIASL 281
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.137 0.399
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 43,299,791
Number of Sequences: 37866
Number of extensions: 1938406
Number of successful extensions: 5889
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 67
Number of HSP's successfully gapped in prelim test: 12
Number of HSP's that attempted gapping in prelim test: 5503
Number of HSP's gapped (non-prelim): 208
length of query: 1170
length of database: 18,247,518
effective HSP length: 113
effective length of query: 1057
effective length of database: 13,968,660
effective search space: 14764873620
effective search space used: 14764873620
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.