BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|48255957 plasma membrane calcium ATPase 4 isoform 4b [Homo sapiens] (1205 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|48255957 plasma membrane calcium ATPase 4 isoform 4b [Homo sa... 2390 0.0 gi|48255959 plasma membrane calcium ATPase 4 isoform 4a [Homo sa... 2195 0.0 gi|48255945 plasma membrane calcium ATPase 1 isoform 1b [Homo sa... 1837 0.0 gi|48255955 plasma membrane calcium ATPase 3 isoform 3b [Homo sa... 1807 0.0 gi|48255947 plasma membrane calcium ATPase 1 isoform 1a [Homo sa... 1776 0.0 gi|48255951 plasma membrane calcium ATPase 2 isoform 1 [Homo sap... 1771 0.0 gi|48255949 plasma membrane calcium ATPase 2 isoform 2 [Homo sap... 1769 0.0 gi|48255953 plasma membrane calcium ATPase 3 isoform 3a [Homo sa... 1757 0.0 gi|28373103 ATPase, Ca++ transporting, ubiquitous isoform a [Hom... 300 7e-81 gi|28373115 ATPase, Ca++ transporting, ubiquitous isoform c [Hom... 300 7e-81 gi|28373113 ATPase, Ca++ transporting, ubiquitous isoform f [Hom... 300 7e-81 gi|28373111 ATPase, Ca++ transporting, ubiquitous isoform c [Hom... 300 7e-81 gi|28373109 ATPase, Ca++ transporting, ubiquitous isoform b [Hom... 300 7e-81 gi|28373107 ATPase, Ca++ transporting, ubiquitous isoform d [Hom... 300 7e-81 gi|28373105 ATPase, Ca++ transporting, ubiquitous isoform e [Hom... 300 7e-81 gi|10835220 ATPase, Ca++ transporting, fast twitch 1 isoform b [... 295 2e-79 gi|27886529 ATPase, Ca++ transporting, fast twitch 1 isoform a [... 295 2e-79 gi|24638454 ATPase, Ca++ transporting, slow twitch 2 isoform 1 [... 294 4e-79 gi|4502285 ATPase, Ca++ transporting, slow twitch 2 isoform 2 [H... 291 3e-78 gi|48762691 calcium-transporting ATPase 2C1 isoform 1b [Homo sap... 290 4e-78 gi|48762689 calcium-transporting ATPase 2C1 isoform 1d [Homo sap... 290 4e-78 gi|48762685 calcium-transporting ATPase 2C1 isoform 1a [Homo sap... 290 4e-78 gi|48762687 calcium-transporting ATPase 2C1 isoform 1c [Homo sap... 289 1e-77 gi|209413709 ATPase, Ca++ transporting, slow twitch 2 isoform 3 ... 270 8e-72 gi|83700225 hydrogen/potassium-exchanging ATPase 12A [Homo sapiens] 246 9e-65 gi|118498343 ATPase, Ca++ transporting, type 2C, member 2 [Homo ... 243 8e-64 gi|237681109 Na+/K+ -ATPase alpha 1 subunit isoform c [Homo sapi... 237 4e-62 gi|237681111 Na+/K+ -ATPase alpha 1 subunit isoform d [Homo sapi... 237 4e-62 gi|21361181 Na+/K+ -ATPase alpha 1 subunit isoform a [Homo sapiens] 237 4e-62 gi|153946397 Na+/K+ -ATPase alpha 4 subunit isoform 1 [Homo sapi... 225 2e-58 >gi|48255957 plasma membrane calcium ATPase 4 isoform 4b [Homo sapiens] Length = 1205 Score = 2390 bits (6195), Expect = 0.0 Identities = 1205/1205 (100%), Positives = 1205/1205 (100%) Query: 1 MTNPSDRVLPANSMAESREGDFGCTVMELRKLMELRSRDALTQINVHYGGVQNLCSRLKT 60 MTNPSDRVLPANSMAESREGDFGCTVMELRKLMELRSRDALTQINVHYGGVQNLCSRLKT Sbjct: 1 MTNPSDRVLPANSMAESREGDFGCTVMELRKLMELRSRDALTQINVHYGGVQNLCSRLKT 60 Query: 61 SPVEGLSGNPADLEKRRQVFGHNVIPPKKPKTFLELVWEALQDVTLIILEIAAIISLVLS 120 SPVEGLSGNPADLEKRRQVFGHNVIPPKKPKTFLELVWEALQDVTLIILEIAAIISLVLS Sbjct: 61 SPVEGLSGNPADLEKRRQVFGHNVIPPKKPKTFLELVWEALQDVTLIILEIAAIISLVLS 120 Query: 121 FYRPAGEENELCGQVATTPEDENEAQAGWIEGAAILFSVIIVVLVTAFNDWSKEKQFRGL 180 FYRPAGEENELCGQVATTPEDENEAQAGWIEGAAILFSVIIVVLVTAFNDWSKEKQFRGL Sbjct: 121 FYRPAGEENELCGQVATTPEDENEAQAGWIEGAAILFSVIIVVLVTAFNDWSKEKQFRGL 180 Query: 181 QCRIEQEQKFSIIRNGQLIQLPVAEIVVGDIAQVKYGDLLPADGILIQGNDLKIDESSLT 240 QCRIEQEQKFSIIRNGQLIQLPVAEIVVGDIAQVKYGDLLPADGILIQGNDLKIDESSLT Sbjct: 181 QCRIEQEQKFSIIRNGQLIQLPVAEIVVGDIAQVKYGDLLPADGILIQGNDLKIDESSLT 240 Query: 241 GESDHVKKSLDKDPMLLSGTHVMEGSGRMVVTAVGVNSQTGIILTLLGVNEDDEGEKKKK 300 GESDHVKKSLDKDPMLLSGTHVMEGSGRMVVTAVGVNSQTGIILTLLGVNEDDEGEKKKK Sbjct: 241 GESDHVKKSLDKDPMLLSGTHVMEGSGRMVVTAVGVNSQTGIILTLLGVNEDDEGEKKKK 300 Query: 301 GKKQGVPENRNKAKTQDGVALEIQPLNSQEGIDNEEKDKKAVKVPKKEKSVLQGKLTRLA 360 GKKQGVPENRNKAKTQDGVALEIQPLNSQEGIDNEEKDKKAVKVPKKEKSVLQGKLTRLA Sbjct: 301 GKKQGVPENRNKAKTQDGVALEIQPLNSQEGIDNEEKDKKAVKVPKKEKSVLQGKLTRLA 360 Query: 361 VQIGKAGLLMSALTVFILILYFVIDNFVINRRPWLPECTPIYIQYFVKFFIIGITVLVVA 420 VQIGKAGLLMSALTVFILILYFVIDNFVINRRPWLPECTPIYIQYFVKFFIIGITVLVVA Sbjct: 361 VQIGKAGLLMSALTVFILILYFVIDNFVINRRPWLPECTPIYIQYFVKFFIIGITVLVVA 420 Query: 421 VPEGLPLAVTISLAYSVKKMMKDNNLVRHLDACETMGNATAICSDKTGTLTMNRMTVVQA 480 VPEGLPLAVTISLAYSVKKMMKDNNLVRHLDACETMGNATAICSDKTGTLTMNRMTVVQA Sbjct: 421 VPEGLPLAVTISLAYSVKKMMKDNNLVRHLDACETMGNATAICSDKTGTLTMNRMTVVQA 480 Query: 481 YIGGIHYRQIPSPDVFLPKVLDLIVNGISINSAYTSKILPPEKEGGLPRQVGNKTECALL 540 YIGGIHYRQIPSPDVFLPKVLDLIVNGISINSAYTSKILPPEKEGGLPRQVGNKTECALL Sbjct: 481 YIGGIHYRQIPSPDVFLPKVLDLIVNGISINSAYTSKILPPEKEGGLPRQVGNKTECALL 540 Query: 541 GFVTDLKQDYQAVRNEVPEEKLYKVYTFNSVRKSMSTVIRNPNGGFRMYSKGASEIILRK 600 GFVTDLKQDYQAVRNEVPEEKLYKVYTFNSVRKSMSTVIRNPNGGFRMYSKGASEIILRK Sbjct: 541 GFVTDLKQDYQAVRNEVPEEKLYKVYTFNSVRKSMSTVIRNPNGGFRMYSKGASEIILRK 600 Query: 601 CNRILDRKGEAVPFKNKDRDDMVRTVIEPMACDGLRTICIAYRDFDDTEPSWDNENEILT 660 CNRILDRKGEAVPFKNKDRDDMVRTVIEPMACDGLRTICIAYRDFDDTEPSWDNENEILT Sbjct: 601 CNRILDRKGEAVPFKNKDRDDMVRTVIEPMACDGLRTICIAYRDFDDTEPSWDNENEILT 660 Query: 661 ELTCIAVVGIEDPVRPEVPDAIAKCKQAGITVRMVTGDNINTARAIATKCGILTPGDDFL 720 ELTCIAVVGIEDPVRPEVPDAIAKCKQAGITVRMVTGDNINTARAIATKCGILTPGDDFL Sbjct: 661 ELTCIAVVGIEDPVRPEVPDAIAKCKQAGITVRMVTGDNINTARAIATKCGILTPGDDFL 720 Query: 721 CLEGKEFNRLIRNEKGEVEQEKLDKIWPKLRVLARSSPTDKHTLVKGIIDSTVGEHRQVV 780 CLEGKEFNRLIRNEKGEVEQEKLDKIWPKLRVLARSSPTDKHTLVKGIIDSTVGEHRQVV Sbjct: 721 CLEGKEFNRLIRNEKGEVEQEKLDKIWPKLRVLARSSPTDKHTLVKGIIDSTVGEHRQVV 780 Query: 781 AVTGDGTNDGPALKKADVGFAMGIAGTDVAKEASDIILTDDNFTSIVKAVMWGRNVYDSI 840 AVTGDGTNDGPALKKADVGFAMGIAGTDVAKEASDIILTDDNFTSIVKAVMWGRNVYDSI Sbjct: 781 AVTGDGTNDGPALKKADVGFAMGIAGTDVAKEASDIILTDDNFTSIVKAVMWGRNVYDSI 840 Query: 841 SKFLQFQLTVNVVAVIVAFTGACITQDSPLKAVQMLWVNLIMDTFASLALATEPPTESLL 900 SKFLQFQLTVNVVAVIVAFTGACITQDSPLKAVQMLWVNLIMDTFASLALATEPPTESLL Sbjct: 841 SKFLQFQLTVNVVAVIVAFTGACITQDSPLKAVQMLWVNLIMDTFASLALATEPPTESLL 900 Query: 901 KRRPYGRNKPLISRTMMKNILGHAFYQLIVIFILVFAGEKFFDIDSGRKAPLHSPPSQHY 960 KRRPYGRNKPLISRTMMKNILGHAFYQLIVIFILVFAGEKFFDIDSGRKAPLHSPPSQHY Sbjct: 901 KRRPYGRNKPLISRTMMKNILGHAFYQLIVIFILVFAGEKFFDIDSGRKAPLHSPPSQHY 960 Query: 961 TIVFNTFVLMQLFNEINSRKIHGEKNVFSGIYRNIIFCSVVLGTFICQIFIVEFGGKPFS 1020 TIVFNTFVLMQLFNEINSRKIHGEKNVFSGIYRNIIFCSVVLGTFICQIFIVEFGGKPFS Sbjct: 961 TIVFNTFVLMQLFNEINSRKIHGEKNVFSGIYRNIIFCSVVLGTFICQIFIVEFGGKPFS 1020 Query: 1021 CTSLSLSQWLWCLFIGIGELLWGQFISAIPTRSLKFLKEAGHGTTKEEITKDAEGLDEID 1080 CTSLSLSQWLWCLFIGIGELLWGQFISAIPTRSLKFLKEAGHGTTKEEITKDAEGLDEID Sbjct: 1021 CTSLSLSQWLWCLFIGIGELLWGQFISAIPTRSLKFLKEAGHGTTKEEITKDAEGLDEID 1080 Query: 1081 HAEMELRRGQILWFRGLNRIQTQIKVVKAFHSSLHESIQKPYNQKSIHSFMTHPEFAIEE 1140 HAEMELRRGQILWFRGLNRIQTQIKVVKAFHSSLHESIQKPYNQKSIHSFMTHPEFAIEE Sbjct: 1081 HAEMELRRGQILWFRGLNRIQTQIKVVKAFHSSLHESIQKPYNQKSIHSFMTHPEFAIEE 1140 Query: 1141 ELPRTPLLDEEEEENPDKASKFGTRVLLLDGEVTPYANTNNNAVDCNQVQLPQSDSSLQS 1200 ELPRTPLLDEEEEENPDKASKFGTRVLLLDGEVTPYANTNNNAVDCNQVQLPQSDSSLQS Sbjct: 1141 ELPRTPLLDEEEEENPDKASKFGTRVLLLDGEVTPYANTNNNAVDCNQVQLPQSDSSLQS 1200 Query: 1201 LETSV 1205 LETSV Sbjct: 1201 LETSV 1205 >gi|48255959 plasma membrane calcium ATPase 4 isoform 4a [Homo sapiens] Length = 1170 Score = 2195 bits (5687), Expect = 0.0 Identities = 1106/1112 (99%), Positives = 1108/1112 (99%) Query: 1 MTNPSDRVLPANSMAESREGDFGCTVMELRKLMELRSRDALTQINVHYGGVQNLCSRLKT 60 MTNPSDRVLPANSMAESREGDFGCTVMELRKLMELRSRDALTQINVHYGGVQNLCSRLKT Sbjct: 1 MTNPSDRVLPANSMAESREGDFGCTVMELRKLMELRSRDALTQINVHYGGVQNLCSRLKT 60 Query: 61 SPVEGLSGNPADLEKRRQVFGHNVIPPKKPKTFLELVWEALQDVTLIILEIAAIISLVLS 120 SPVEGLSGNPADLEKRRQVFGHNVIPPKKPKTFLELVWEALQDVTLIILEIAAIISLVLS Sbjct: 61 SPVEGLSGNPADLEKRRQVFGHNVIPPKKPKTFLELVWEALQDVTLIILEIAAIISLVLS 120 Query: 121 FYRPAGEENELCGQVATTPEDENEAQAGWIEGAAILFSVIIVVLVTAFNDWSKEKQFRGL 180 FYRPAGEENELCGQVATTPEDENEAQAGWIEGAAILFSVIIVVLVTAFNDWSKEKQFRGL Sbjct: 121 FYRPAGEENELCGQVATTPEDENEAQAGWIEGAAILFSVIIVVLVTAFNDWSKEKQFRGL 180 Query: 181 QCRIEQEQKFSIIRNGQLIQLPVAEIVVGDIAQVKYGDLLPADGILIQGNDLKIDESSLT 240 QCRIEQEQKFSIIRNGQLIQLPVAEIVVGDIAQVKYGDLLPADGILIQGNDLKIDESSLT Sbjct: 181 QCRIEQEQKFSIIRNGQLIQLPVAEIVVGDIAQVKYGDLLPADGILIQGNDLKIDESSLT 240 Query: 241 GESDHVKKSLDKDPMLLSGTHVMEGSGRMVVTAVGVNSQTGIILTLLGVNEDDEGEKKKK 300 GESDHVKKSLDKDPMLLSGTHVMEGSGRMVVTAVGVNSQTGIILTLLGVNEDDEGEKKKK Sbjct: 241 GESDHVKKSLDKDPMLLSGTHVMEGSGRMVVTAVGVNSQTGIILTLLGVNEDDEGEKKKK 300 Query: 301 GKKQGVPENRNKAKTQDGVALEIQPLNSQEGIDNEEKDKKAVKVPKKEKSVLQGKLTRLA 360 GKKQGVPENRNKAKTQDGVALEIQPLNSQEGIDNEEKDKKAVKVPKKEKSVLQGKLTRLA Sbjct: 301 GKKQGVPENRNKAKTQDGVALEIQPLNSQEGIDNEEKDKKAVKVPKKEKSVLQGKLTRLA 360 Query: 361 VQIGKAGLLMSALTVFILILYFVIDNFVINRRPWLPECTPIYIQYFVKFFIIGITVLVVA 420 VQIGKAGLLMSALTVFILILYFVIDNFVINRRPWLPECTPIYIQYFVKFFIIGITVLVVA Sbjct: 361 VQIGKAGLLMSALTVFILILYFVIDNFVINRRPWLPECTPIYIQYFVKFFIIGITVLVVA 420 Query: 421 VPEGLPLAVTISLAYSVKKMMKDNNLVRHLDACETMGNATAICSDKTGTLTMNRMTVVQA 480 VPEGLPLAVTISLAYSVKKMMKDNNLVRHLDACETMGNATAICSDKTGTLTMNRMTVVQA Sbjct: 421 VPEGLPLAVTISLAYSVKKMMKDNNLVRHLDACETMGNATAICSDKTGTLTMNRMTVVQA 480 Query: 481 YIGGIHYRQIPSPDVFLPKVLDLIVNGISINSAYTSKILPPEKEGGLPRQVGNKTECALL 540 YIGGIHYRQIPSPDVFLPKVLDLIVNGISINSAYTSKILPPEKEGGLPRQVGNKTECALL Sbjct: 481 YIGGIHYRQIPSPDVFLPKVLDLIVNGISINSAYTSKILPPEKEGGLPRQVGNKTECALL 540 Query: 541 GFVTDLKQDYQAVRNEVPEEKLYKVYTFNSVRKSMSTVIRNPNGGFRMYSKGASEIILRK 600 GFVTDLKQDYQAVRNEVPEEKLYKVYTFNSVRKSMSTVIRNPNGGFRMYSKGASEIILRK Sbjct: 541 GFVTDLKQDYQAVRNEVPEEKLYKVYTFNSVRKSMSTVIRNPNGGFRMYSKGASEIILRK 600 Query: 601 CNRILDRKGEAVPFKNKDRDDMVRTVIEPMACDGLRTICIAYRDFDDTEPSWDNENEILT 660 CNRILDRKGEAVPFKNKDRDDMVRTVIEPMACDGLRTICIAYRDFDDTEPSWDNENEILT Sbjct: 601 CNRILDRKGEAVPFKNKDRDDMVRTVIEPMACDGLRTICIAYRDFDDTEPSWDNENEILT 660 Query: 661 ELTCIAVVGIEDPVRPEVPDAIAKCKQAGITVRMVTGDNINTARAIATKCGILTPGDDFL 720 ELTCIAVVGIEDPVRPEVPDAIAKCKQAGITVRMVTGDNINTARAIATKCGILTPGDDFL Sbjct: 661 ELTCIAVVGIEDPVRPEVPDAIAKCKQAGITVRMVTGDNINTARAIATKCGILTPGDDFL 720 Query: 721 CLEGKEFNRLIRNEKGEVEQEKLDKIWPKLRVLARSSPTDKHTLVKGIIDSTVGEHRQVV 780 CLEGKEFNRLIRNEKGEVEQEKLDKIWPKLRVLARSSPTDKHTLVKGIIDSTVGEHRQVV Sbjct: 721 CLEGKEFNRLIRNEKGEVEQEKLDKIWPKLRVLARSSPTDKHTLVKGIIDSTVGEHRQVV 780 Query: 781 AVTGDGTNDGPALKKADVGFAMGIAGTDVAKEASDIILTDDNFTSIVKAVMWGRNVYDSI 840 AVTGDGTNDGPALKKADVGFAMGIAGTDVAKEASDIILTDDNFTSIVKAVMWGRNVYDSI Sbjct: 781 AVTGDGTNDGPALKKADVGFAMGIAGTDVAKEASDIILTDDNFTSIVKAVMWGRNVYDSI 840 Query: 841 SKFLQFQLTVNVVAVIVAFTGACITQDSPLKAVQMLWVNLIMDTFASLALATEPPTESLL 900 SKFLQFQLTVNVVAVIVAFTGACITQDSPLKAVQMLWVNLIMDTFASLALATEPPTESLL Sbjct: 841 SKFLQFQLTVNVVAVIVAFTGACITQDSPLKAVQMLWVNLIMDTFASLALATEPPTESLL 900 Query: 901 KRRPYGRNKPLISRTMMKNILGHAFYQLIVIFILVFAGEKFFDIDSGRKAPLHSPPSQHY 960 KRRPYGRNKPLISRTMMKNILGHAFYQLIVIFILVFAGEKFFDIDSGRKAPLHSPPSQHY Sbjct: 901 KRRPYGRNKPLISRTMMKNILGHAFYQLIVIFILVFAGEKFFDIDSGRKAPLHSPPSQHY 960 Query: 961 TIVFNTFVLMQLFNEINSRKIHGEKNVFSGIYRNIIFCSVVLGTFICQIFIVEFGGKPFS 1020 TIVFNTFVLMQLFNEINSRKIHGEKNVFSGIYRNIIFCSVVLGTFICQIFIVEFGGKPFS Sbjct: 961 TIVFNTFVLMQLFNEINSRKIHGEKNVFSGIYRNIIFCSVVLGTFICQIFIVEFGGKPFS 1020 Query: 1021 CTSLSLSQWLWCLFIGIGELLWGQFISAIPTRSLKFLKEAGHGTTKEEITKDAEGLDEID 1080 CTSLSLSQWLWCLFIGIGELLWGQFISAIPTRSLKFLKEAGHGTTKEEITKDAEGLDEID Sbjct: 1021 CTSLSLSQWLWCLFIGIGELLWGQFISAIPTRSLKFLKEAGHGTTKEEITKDAEGLDEID 1080 Query: 1081 HAEMELRRGQILWFRGLNRIQTQIKVVKAFHS 1112 HAEMELRRGQILWFRGLNRIQTQI V+ F + Sbjct: 1081 HAEMELRRGQILWFRGLNRIQTQIDVINTFQT 1112 >gi|48255945 plasma membrane calcium ATPase 1 isoform 1b [Homo sapiens] Length = 1220 Score = 1837 bits (4758), Expect = 0.0 Identities = 928/1214 (76%), Positives = 1044/1214 (85%), Gaps = 29/1214 (2%) Query: 12 NSMAESR-EGDFGCTVMELRKLMELRSRDALTQINVHYGGVQNLCSRLKTSPVEGLSGNP 70 NS+ E+ +GDFG T+ ELR LMELRS DAL +I YG V +C++LKTSP EGLSGNP Sbjct: 16 NSLKEANHDGDFGITLAELRALMELRSTDALRKIQESYGDVYGICTKLKTSPNEGLSGNP 75 Query: 71 ADLEKRRQVFGHNVIPPKKPKTFLELVWEALQDVTLIILEIAAIISLVLSFYRPAGEENE 130 ADLE+R VFG N IPPKKPKTFL+LVWEALQDVTLIILEIAAI+SL LSFY+P +N Sbjct: 76 ADLERREAVFGKNFIPPKKPKTFLQLVWEALQDVTLIILEIAAIVSLGLSFYQPPEGDNA 135 Query: 131 LCGQVATTPEDENEAQAGWIEGAAILFSVIIVVLVTAFNDWSKEKQFRGLQCRIEQEQKF 190 LCG+V+ E+E E + GWIEGAAIL SV+ VVLVTAFNDWSKEKQFRGLQ RIEQEQKF Sbjct: 136 LCGEVSVG-EEEGEGETGWIEGAAILLSVVCVVLVTAFNDWSKEKQFRGLQSRIEQEQKF 194 Query: 191 SIIRNGQLIQLPVAEIVVGDIAQVKYGDLLPADGILIQGNDLKIDESSLTGESDHVKKSL 250 ++IR GQ+IQ+PVA+I VGDIAQVKYGDLLPADGILIQGNDLKIDESSLTGESDHVKKSL Sbjct: 195 TVIRGGQVIQIPVADITVGDIAQVKYGDLLPADGILIQGNDLKIDESSLTGESDHVKKSL 254 Query: 251 DKDPMLLSGTHVMEGSGRMVVTAVGVNSQTGIILTLLGVNED-----DEGEKKKKGKKQ- 304 DKDP+LLSGTHVMEGSGRMVVTAVGVNSQTGII TLLG + DE +K+KK KKQ Sbjct: 255 DKDPLLLSGTHVMEGSGRMVVTAVGVNSQTGIIFTLLGAGGEEEEKKDEKKKEKKNKKQD 314 Query: 305 GVPENRNKAKTQDGVALEIQPLNSQEGIDNEEKDKKAVKVPKKEKSVLQGKLTRLAVQIG 364 G ENRNKAK QDG A+E+QPL S+EG D +EKDKK +PKKEKSVLQGKLT+LAVQIG Sbjct: 315 GAIENRNKAKAQDGAAMEMQPLKSEEGGDGDEKDKKKANLPKKEKSVLQGKLTKLAVQIG 374 Query: 365 KAGLLMSALTVFILILYFVIDNFVINRRPWLPECTPIYIQYFVKFFIIGITVLVVAVPEG 424 KAGLLMSA+TV IL+LYFVID F + +RPWL ECTPIYIQYFVKFFIIG+TVLVVAVPEG Sbjct: 375 KAGLLMSAITVIILVLYFVIDTFWVQKRPWLAECTPIYIQYFVKFFIIGVTVLVVAVPEG 434 Query: 425 LPLAVTISLAYSVKKMMKDNNLVRHLDACETMGNATAICSDKTGTLTMNRMTVVQAYIGG 484 LPLAVTISLAYSVKKMMKDNNLVRHLDACETMGNATAICSDKTGTLTMNRMTVVQAYI Sbjct: 435 LPLAVTISLAYSVKKMMKDNNLVRHLDACETMGNATAICSDKTGTLTMNRMTVVQAYINE 494 Query: 485 IHYRQIPSPDVFLPKVLDLIVNGISINSAYTSKILPPEKEGGLPRQVGNKTECALLGFVT 544 HY+++P P+ P +L +V GIS+N AYTSKILPPEKEGGLPR VGNKTECALLG + Sbjct: 495 KHYKKVPEPEAIPPNILSYLVTGISVNCAYTSKILPPEKEGGLPRHVGNKTECALLGLLL 554 Query: 545 DLKQDYQAVRNEVPEEKLYKVYTFNSVRKSMSTVIRNPNGGFRMYSKGASEIILRKCNRI 604 DLK+DYQ VRNE+PEE LYKVYTFNSVRKSMSTV++N +G +R++SKGASEIIL+KC +I Sbjct: 555 DLKRDYQDVRNEIPEEALYKVYTFNSVRKSMSTVLKNSDGSYRIFSKGASEIILKKCFKI 614 Query: 605 LDRKGEAVPFKNKDRDDMVRTVIEPMACDGLRTICIAYRDFD--DTEPSWDNENEILTEL 662 L GEA F+ +DRDD+V+TVIEPMA +GLRTIC+A+RDF + EP WDNEN+I+T L Sbjct: 615 LSANGEAKVFRPRDRDDIVKTVIEPMASEGLRTICLAFRDFPAGEPEPEWDNENDIVTGL 674 Query: 663 TCIAVVGIEDPVRPEVPDAIAKCKQAGITVRMVTGDNINTARAIATKCGILTPGDDFLCL 722 TCIAVVGIEDPVRPEVPDAI KC++AGITVRMVTGDNINTARAIATKCGIL PG+DFLCL Sbjct: 675 TCIAVVGIEDPVRPEVPDAIKKCQRAGITVRMVTGDNINTARAIATKCGILHPGEDFLCL 734 Query: 723 EGKEFNRLIRNEKGEVEQEKLDKIWPKLRVLARSSPTDKHTLVKGIIDSTVGEHRQVVAV 782 EGK+FNR IRNEKGE+EQE++DKIWPKLRVLARSSPTDKHTLVKGIIDSTV + RQVVAV Sbjct: 735 EGKDFNRRIRNEKGEIEQERIDKIWPKLRVLARSSPTDKHTLVKGIIDSTVSDQRQVVAV 794 Query: 783 TGDGTNDGPALKKADVGFAMGIAGTDVAKEASDIILTDDNFTSIVKAVMWGRNVYDSISK 842 TGDGTNDGPALKKADVGFAMGIAGTDVAKEASDIILTDDNFTSIVKAVMWGRNVYDSISK Sbjct: 795 TGDGTNDGPALKKADVGFAMGIAGTDVAKEASDIILTDDNFTSIVKAVMWGRNVYDSISK 854 Query: 843 FLQFQLTVNVVAVIVAFTGACITQDSPLKAVQMLWVNLIMDTFASLALATEPPTESLLKR 902 FLQFQLTVNVVAVIVAFTGACITQDSPLKAVQMLWVNLIMDT ASLALATEPPTESLL R Sbjct: 855 FLQFQLTVNVVAVIVAFTGACITQDSPLKAVQMLWVNLIMDTLASLALATEPPTESLLLR 914 Query: 903 RPYGRNKPLISRTMMKNILGHAFYQLIVIFILVFAGEKFFDIDSGRKAPLHSPPSQHYTI 962 +PYGRNKPLISRTMMKNILGHAFYQL+V+F L+FAGEKFFDIDSGR APLH+PPS+HYTI Sbjct: 915 KPYGRNKPLISRTMMKNILGHAFYQLVVVFTLLFAGEKFFDIDSGRNAPLHAPPSEHYTI 974 Query: 963 VFNTFVLMQLFNEINSRKIHGEKNVFSGIYRNIIFCSVVLGTFICQIFIVEFGGKPFSCT 1022 VFNTFVLMQLFNEIN+RKIHGE+NVF GI+ N IFC++VLGTF+ QI IV+FGGKPFSC+ Sbjct: 975 VFNTFVLMQLFNEINARKIHGERNVFEGIFNNAIFCTIVLGTFVVQIIIVQFGGKPFSCS 1034 Query: 1023 SLSLSQWLWCLFIGIGELLWGQFISAIPTRSLKFLKEAGHGTTKEEITKD--AEGLDEID 1080 LS+ QWLW +F+G+G LLWGQ IS IPT LKFLKEAGHGT KEEI ++ AE ++EID Sbjct: 1035 ELSIEQWLWSIFLGMGTLLWGQLISTIPTSRLKFLKEAGHGTQKEEIPEEELAEDVEEID 1094 Query: 1081 HAEMELRRGQILWFRGLNRIQTQIKVVKAFHSSLHESIQKPYNQKSIHSFMTHPEFAIEE 1140 HAE ELRRGQILWFRGLNRIQTQI+VV AF SSL+E ++KP ++ SIH+FMTHPEF IE+ Sbjct: 1095 HAERELRRGQILWFRGLNRIQTQIRVVNAFRSSLYEGLEKPESRSSIHNFMTHPEFRIED 1154 Query: 1141 ELPRTPLLDEEEEENPDKASKFGTRVLLLDGEVTPYANTNNNAVDCN---QVQLPQSDSS 1197 P PL+D+ + E+ + + P N NNNAVD +++ +S +S Sbjct: 1155 SEPHIPLIDDTDAEDDAPTKR--------NSSPPPSPNKNNNAVDSGIHLTIEMNKSATS 1206 Query: 1198 ------LQSLETSV 1205 L SLETS+ Sbjct: 1207 SSPGSPLHSLETSL 1220 >gi|48255955 plasma membrane calcium ATPase 3 isoform 3b [Homo sapiens] Length = 1220 Score = 1807 bits (4681), Expect = 0.0 Identities = 903/1173 (76%), Positives = 1015/1173 (86%), Gaps = 17/1173 (1%) Query: 20 GDFGCTVMELRKLMELRSRDALTQINVHYGGVQNLCSRLKTSPVEGLSGNPADLEKRRQV 79 G FGCT+ ELR LMELR +AL +I YG V LC RLKTSP EGL+ N DLEKRRQ+ Sbjct: 25 GGFGCTLAELRTLMELRGAEALQKIEEAYGDVSGLCRRLKTSPTEGLADNTNDLEKRRQI 84 Query: 80 FGHNVIPPKKPKTFLELVWEALQDVTLIILEIAAIISLVLSFYRPAGEENELCGQVATTP 139 +G N IPPK+PKTFL+LVWEALQDVTLIILE+AAI+SL LSFY P GEE+E CG V+ Sbjct: 85 YGQNFIPPKQPKTFLQLVWEALQDVTLIILEVAAIVSLGLSFYAPPGEESEACGNVSGGA 144 Query: 140 EDENEAQAGWIEGAAILFSVIIVVLVTAFNDWSKEKQFRGLQCRIEQEQKFSIIRNGQLI 199 EDE EA+AGWIEGAAIL SVI VVLVTAFNDWSKEKQFRGLQ RIEQEQKF++IRNGQL+ Sbjct: 145 EDEGEAEAGWIEGAAILLSVICVVLVTAFNDWSKEKQFRGLQSRIEQEQKFTVIRNGQLL 204 Query: 200 QLPVAEIVVGDIAQVKYGDLLPADGILIQGNDLKIDESSLTGESDHVKKSLDKDPMLLSG 259 Q+PVA +VVGDIAQVKYGDLLPADG+LIQ NDLKIDESSLTGESDHV+KS DKDPMLLSG Sbjct: 205 QVPVAALVVGDIAQVKYGDLLPADGVLIQANDLKIDESSLTGESDHVRKSADKDPMLLSG 264 Query: 260 THVMEGSGRMVVTAVGVNSQTGIILTLLGVNEDDEGEKKKKGKKQ--GVPENRNKAKTQD 317 THVMEGSGRMVVTAVGVNSQTGII TLLG ++E +K KKGK+Q + ++ KAK QD Sbjct: 265 THVMEGSGRMVVTAVGVNSQTGIIFTLLGAGGEEEEKKDKKGKQQDGAMESSQTKAKKQD 324 Query: 318 G-VALEIQPLNSQEGIDNEEKDKKAVKVPKKEKSVLQGKLTRLAVQIGKAGLLMSALTVF 376 G VA+E+QPL S EG + EE++KK PKKEKSVLQGKLT+LAVQIGKAGL+MSA+TV Sbjct: 325 GAVAMEMQPLKSAEGGEMEEREKKKANAPKKEKSVLQGKLTKLAVQIGKAGLVMSAITVI 384 Query: 377 ILILYFVIDNFVINRRPWLPECTPIYIQYFVKFFIIGITVLVVAVPEGLPLAVTISLAYS 436 IL+LYFVI+ FV+ R WL ECTP+Y+QYFVKFFIIG+TVLVVAVPEGLPLAVTISLAYS Sbjct: 385 ILVLYFVIETFVVEGRTWLAECTPVYVQYFVKFFIIGVTVLVVAVPEGLPLAVTISLAYS 444 Query: 437 VKKMMKDNNLVRHLDACETMGNATAICSDKTGTLTMNRMTVVQAYIGGIHYRQIPSPDVF 496 VKKMMKDNNLVRHLDACETMGNATAICSDKTGTLT NRMTVVQ+Y+G HY++IP+P Sbjct: 445 VKKMMKDNNLVRHLDACETMGNATAICSDKTGTLTTNRMTVVQSYLGDTHYKEIPAPSAL 504 Query: 497 LPKVLDLIVNGISINSAYTSKILPPEKEGGLPRQVGNKTECALLGFVTDLKQDYQAVRNE 556 PK+LDL+V+ ISINSAYT+KILPPEKEG LPRQVGNKTECALLGFV DLK+D+Q VR + Sbjct: 505 TPKILDLLVHAISINSAYTTKILPPEKEGALPRQVGNKTECALLGFVLDLKRDFQPVREQ 564 Query: 557 VPEEKLYKVYTFNSVRKSMSTVIRNPNGGFRMYSKGASEIILRKCNRILDRKGEAVPFKN 616 +PE+KLYKVYTFNSVRKSMSTVIR P+GGFR++SKGASEI+L+KC IL+ GE F+ Sbjct: 565 IPEDKLYKVYTFNSVRKSMSTVIRMPDGGFRLFSKGASEILLKKCTNILNSNGELRGFRP 624 Query: 617 KDRDDMVRTVIEPMACDGLRTICIAYRDFD-DTEPSWDNENEILTELTCIAVVGIEDPVR 675 +DRDDMVR +IEPMACDGLRTICIAYRDF EP WDNENE++ +LTCIAVVGIEDPVR Sbjct: 625 RDRDDMVRKIIEPMACDGLRTICIAYRDFSAGQEPDWDNENEVVGDLTCIAVVGIEDPVR 684 Query: 676 PEVPDAIAKCKQAGITVRMVTGDNINTARAIATKCGILTPGDDFLCLEGKEFNRLIRNEK 735 PEVP+AI KC++AGITVRMVTGDNINTARAIA KCGI+ PG+DFLCLEGKEFNR IRNEK Sbjct: 685 PEVPEAIRKCQRAGITVRMVTGDNINTARAIAAKCGIIQPGEDFLCLEGKEFNRRIRNEK 744 Query: 736 GEVEQEKLDKIWPKLRVLARSSPTDKHTLVKGIIDSTVGEHRQVVAVTGDGTNDGPALKK 795 GE+EQE+LDK+WPKLRVLARSSPTDKHTLVKGIIDST GE RQVVAVTGDGTNDGPALKK Sbjct: 745 GEIEQERLDKVWPKLRVLARSSPTDKHTLVKGIIDSTTGEQRQVVAVTGDGTNDGPALKK 804 Query: 796 ADVGFAMGIAGTDVAKEASDIILTDDNFTSIVKAVMWGRNVYDSISKFLQFQLTVNVVAV 855 ADVGFAMGIAGTDVAKEASDIILTDDNFTSIVKAVMWGRNVYDSISKFLQFQLTVNVVAV Sbjct: 805 ADVGFAMGIAGTDVAKEASDIILTDDNFTSIVKAVMWGRNVYDSISKFLQFQLTVNVVAV 864 Query: 856 IVAFTGACITQDSPLKAVQMLWVNLIMDTFASLALATEPPTESLLKRRPYGRNKPLISRT 915 IVAFTGACITQDSPLKAVQMLWVNLIMDTFASLALATEPPTESLL R+PYGR+KPLISRT Sbjct: 865 IVAFTGACITQDSPLKAVQMLWVNLIMDTFASLALATEPPTESLLLRKPYGRDKPLISRT 924 Query: 916 MMKNILGHAFYQLIVIFILVFAGEKFFDIDSGRKAPLHSPPSQHYTIVFNTFVLMQLFNE 975 MMKNILGHA YQL +IF L+F GE FFDIDSGR APLHSPPS+HYTI+FNTFV+MQLFNE Sbjct: 925 MMKNILGHAVYQLAIIFTLLFVGELFFDIDSGRNAPLHSPPSEHYTIIFNTFVMMQLFNE 984 Query: 976 INSRKIHGEKNVFSGIYRNIIFCSVVLGTFICQIFIVEFGGKPFSCTSLSLSQWLWCLFI 1035 IN+RKIHGE+NVF GI+ N IFC++VLGTF QI IV+FGGKPFSC+ LS QWLWCLF+ Sbjct: 985 INARKIHGERNVFDGIFSNPIFCTIVLGTFGIQIVIVQFGGKPFSCSPLSTEQWLWCLFV 1044 Query: 1036 GIGELLWGQFISAIPTRSLKFLKEAGHGTTKEEITKD--AEGLDEIDHAEMELRRGQILW 1093 G+GEL+WGQ I+ IPT LK LKEAGHG K+E+T + AEG +EIDHAE ELRRGQILW Sbjct: 1045 GVGELVWGQVIATIPTSQLKCLKEAGHGPGKDEMTDEELAEGEEEIDHAERELRRGQILW 1104 Query: 1094 FRGLNRIQTQIKVVKAFHSSLHESIQKPYNQKSIHSFMTHPEFAIEEELPRTPLLDEEE- 1152 FRGLNRIQTQI+VVKAF SSL+E ++KP ++ SIH+FM PEF I + PL+D+ + Sbjct: 1105 FRGLNRIQTQIRVVKAFRSSLYEGLEKPESKTSIHNFMATPEFLINDYTHNIPLIDDTDV 1164 Query: 1153 EENPDKASKFGTRVLLLDGEVTPYANTNNNAVD 1185 +EN ++ L P N NNNA+D Sbjct: 1165 DENEER----------LRAPPPPSPNQNNNAID 1187 >gi|48255947 plasma membrane calcium ATPase 1 isoform 1a [Homo sapiens] Length = 1176 Score = 1776 bits (4599), Expect = 0.0 Identities = 893/1135 (78%), Positives = 998/1135 (87%), Gaps = 14/1135 (1%) Query: 12 NSMAESR-EGDFGCTVMELRKLMELRSRDALTQINVHYGGVQNLCSRLKTSPVEGLSGNP 70 NS+ E+ +GDFG T+ ELR LMELRS DAL +I YG V +C++LKTSP EGLSGNP Sbjct: 16 NSLKEANHDGDFGITLAELRALMELRSTDALRKIQESYGDVYGICTKLKTSPNEGLSGNP 75 Query: 71 ADLEKRRQVFGHNVIPPKKPKTFLELVWEALQDVTLIILEIAAIISLVLSFYRPAGEENE 130 ADLE+R VFG N IPPKKPKTFL+LVWEALQDVTLIILEIAAI+SL LSFY+P +N Sbjct: 76 ADLERREAVFGKNFIPPKKPKTFLQLVWEALQDVTLIILEIAAIVSLGLSFYQPPEGDNA 135 Query: 131 LCGQVATTPEDENEAQAGWIEGAAILFSVIIVVLVTAFNDWSKEKQFRGLQCRIEQEQKF 190 LCG+V+ E+E E + GWIEGAAIL SV+ VVLVTAFNDWSKEKQFRGLQ RIEQEQKF Sbjct: 136 LCGEVSVG-EEEGEGETGWIEGAAILLSVVCVVLVTAFNDWSKEKQFRGLQSRIEQEQKF 194 Query: 191 SIIRNGQLIQLPVAEIVVGDIAQVKYGDLLPADGILIQGNDLKIDESSLTGESDHVKKSL 250 ++IR GQ+IQ+PVA+I VGDIAQVKYGDLLPADGILIQGNDLKIDESSLTGESDHVKKSL Sbjct: 195 TVIRGGQVIQIPVADITVGDIAQVKYGDLLPADGILIQGNDLKIDESSLTGESDHVKKSL 254 Query: 251 DKDPMLLSGTHVMEGSGRMVVTAVGVNSQTGIILTLLGVNED-----DEGEKKKKGKKQ- 304 DKDP+LLSGTHVMEGSGRMVVTAVGVNSQTGII TLLG + DE +K+KK KKQ Sbjct: 255 DKDPLLLSGTHVMEGSGRMVVTAVGVNSQTGIIFTLLGAGGEEEEKKDEKKKEKKNKKQD 314 Query: 305 GVPENRNKAKTQDGVALEIQPLNSQEGIDNEEKDKKAVKVPKKEKSVLQGKLTRLAVQIG 364 G ENRNKAK QDG A+E+QPL S+EG D +EKDKK +PKKEKSVLQGKLT+LAVQIG Sbjct: 315 GAIENRNKAKAQDGAAMEMQPLKSEEGGDGDEKDKKKANLPKKEKSVLQGKLTKLAVQIG 374 Query: 365 KAGLLMSALTVFILILYFVIDNFVINRRPWLPECTPIYIQYFVKFFIIGITVLVVAVPEG 424 KAGLLMSA+TV IL+LYFVID F + +RPWL ECTPIYIQYFVKFFIIG+TVLVVAVPEG Sbjct: 375 KAGLLMSAITVIILVLYFVIDTFWVQKRPWLAECTPIYIQYFVKFFIIGVTVLVVAVPEG 434 Query: 425 LPLAVTISLAYSVKKMMKDNNLVRHLDACETMGNATAICSDKTGTLTMNRMTVVQAYIGG 484 LPLAVTISLAYSVKKMMKDNNLVRHLDACETMGNATAICSDKTGTLTMNRMTVVQAYI Sbjct: 435 LPLAVTISLAYSVKKMMKDNNLVRHLDACETMGNATAICSDKTGTLTMNRMTVVQAYINE 494 Query: 485 IHYRQIPSPDVFLPKVLDLIVNGISINSAYTSKILPPEKEGGLPRQVGNKTECALLGFVT 544 HY+++P P+ P +L +V GIS+N AYTSKILPPEKEGGLPR VGNKTECALLG + Sbjct: 495 KHYKKVPEPEAIPPNILSYLVTGISVNCAYTSKILPPEKEGGLPRHVGNKTECALLGLLL 554 Query: 545 DLKQDYQAVRNEVPEEKLYKVYTFNSVRKSMSTVIRNPNGGFRMYSKGASEIILRKCNRI 604 DLK+DYQ VRNE+PEE LYKVYTFNSVRKSMSTV++N +G +R++SKGASEIIL+KC +I Sbjct: 555 DLKRDYQDVRNEIPEEALYKVYTFNSVRKSMSTVLKNSDGSYRIFSKGASEIILKKCFKI 614 Query: 605 LDRKGEAVPFKNKDRDDMVRTVIEPMACDGLRTICIAYRDFD--DTEPSWDNENEILTEL 662 L GEA F+ +DRDD+V+TVIEPMA +GLRTIC+A+RDF + EP WDNEN+I+T L Sbjct: 615 LSANGEAKVFRPRDRDDIVKTVIEPMASEGLRTICLAFRDFPAGEPEPEWDNENDIVTGL 674 Query: 663 TCIAVVGIEDPVRPEVPDAIAKCKQAGITVRMVTGDNINTARAIATKCGILTPGDDFLCL 722 TCIAVVGIEDPVRPEVPDAI KC++AGITVRMVTGDNINTARAIATKCGIL PG+DFLCL Sbjct: 675 TCIAVVGIEDPVRPEVPDAIKKCQRAGITVRMVTGDNINTARAIATKCGILHPGEDFLCL 734 Query: 723 EGKEFNRLIRNEKGEVEQEKLDKIWPKLRVLARSSPTDKHTLVKGIIDSTVGEHRQVVAV 782 EGK+FNR IRNEKGE+EQE++DKIWPKLRVLARSSPTDKHTLVKGIIDSTV + RQVVAV Sbjct: 735 EGKDFNRRIRNEKGEIEQERIDKIWPKLRVLARSSPTDKHTLVKGIIDSTVSDQRQVVAV 794 Query: 783 TGDGTNDGPALKKADVGFAMGIAGTDVAKEASDIILTDDNFTSIVKAVMWGRNVYDSISK 842 TGDGTNDGPALKKADVGFAMGIAGTDVAKEASDIILTDDNFTSIVKAVMWGRNVYDSISK Sbjct: 795 TGDGTNDGPALKKADVGFAMGIAGTDVAKEASDIILTDDNFTSIVKAVMWGRNVYDSISK 854 Query: 843 FLQFQLTVNVVAVIVAFTGACITQDSPLKAVQMLWVNLIMDTFASLALATEPPTESLLKR 902 FLQFQLTVNVVAVIVAFTGACITQDSPLKAVQMLWVNLIMDT ASLALATEPPTESLL R Sbjct: 855 FLQFQLTVNVVAVIVAFTGACITQDSPLKAVQMLWVNLIMDTLASLALATEPPTESLLLR 914 Query: 903 RPYGRNKPLISRTMMKNILGHAFYQLIVIFILVFAGEKFFDIDSGRKAPLHSPPSQHYTI 962 +PYGRNKPLISRTMMKNILGHAFYQL+V+F L+FAGEKFFDIDSGR APLH+PPS+HYTI Sbjct: 915 KPYGRNKPLISRTMMKNILGHAFYQLVVVFTLLFAGEKFFDIDSGRNAPLHAPPSEHYTI 974 Query: 963 VFNTFVLMQLFNEINSRKIHGEKNVFSGIYRNIIFCSVVLGTFICQIFIVEFGGKPFSCT 1022 VFNTFVLMQLFNEIN+RKIHGE+NVF GI+ N IFC++VLGTF+ QI IV+FGGKPFSC+ Sbjct: 975 VFNTFVLMQLFNEINARKIHGERNVFEGIFNNAIFCTIVLGTFVVQIIIVQFGGKPFSCS 1034 Query: 1023 SLSLSQWLWCLFIGIGELLWGQFISAIPTRSLKFLKEAGHGTTKEEITKD--AEGLDEID 1080 LS+ QWLW +F+G+G LLWGQ IS IPT LKFLKEAGHGT KEEI ++ AE ++EID Sbjct: 1035 ELSIEQWLWSIFLGMGTLLWGQLISTIPTSRLKFLKEAGHGTQKEEIPEEELAEDVEEID 1094 Query: 1081 HAEMELRRGQILWFRGLNRIQTQIKVVKAFH--SSLHESIQKPYNQKSIHSFMTH 1133 HAE ELRRGQILWFRGLNRIQTQ+ VV AF SS+ ++++ + S H +T+ Sbjct: 1095 HAERELRRGQILWFRGLNRIQTQMDVVNAFQSGSSIQGALRRQPSIASQHHDVTN 1149 >gi|48255951 plasma membrane calcium ATPase 2 isoform 1 [Homo sapiens] Length = 1243 Score = 1771 bits (4586), Expect = 0.0 Identities = 900/1249 (72%), Positives = 1024/1249 (81%), Gaps = 53/1249 (4%) Query: 1 MTNPSDRVLPANSMAESREGDFGCTVMELRKLMELRSRDALTQINVHYGGVQNLCSRLKT 60 MTN SD S G+FGCT+ ELR LMELR +A+ +I YG + +C RLKT Sbjct: 4 MTN-SDFYSKNQRNESSHGGEFGCTMEELRSLMELRGTEAVVKIKETYGDTEAICRRLKT 62 Query: 61 SPVEGLSGNPADLEKRRQVFGHNVIPPKKPKTFLELVWEALQDVTLIILEIAAIISLVLS 120 SPVEGL G DLEKR+Q+FG N IPPKKPKTFL+LVWEALQDVTLIILEIAAIISL LS Sbjct: 63 SPVEGLPGTAPDLEKRKQIFGQNFIPPKKPKTFLQLVWEALQDVTLIILEIAAIISLGLS 122 Query: 121 FYRPAGEENELCGQVATTPEDENEAQAGWIEGAAILFSVIIVVLVTAFNDWSKEKQFRGL 180 FY P GE NE C EDE EA+AGWIEGAAIL SVI VVLVTAFNDWSKEKQFRGL Sbjct: 123 FYHPPGEGNEGCATAQGGAEDEGEAEAGWIEGAAILLSVICVVLVTAFNDWSKEKQFRGL 182 Query: 181 QCRIEQEQKFSIIRNGQLIQLPVAEIVVGDIAQVKYGDLLPADGILIQGNDLKIDESSLT 240 Q RIEQEQKF+++R GQ++Q+PVAEIVVGDIAQVKYGDLLPADG+ IQGNDLKIDESSLT Sbjct: 183 QSRIEQEQKFTVVRAGQVVQIPVAEIVVGDIAQVKYGDLLPADGLFIQGNDLKIDESSLT 242 Query: 241 GESDHVKKSLDKDPMLLSGTHVMEGSGRMVVTAVGVNSQTGIILTLLGVNEDDEGEKKKK 300 GESD V+KS+DKDPMLLSGTHVMEGSGRM+VTAVGVNSQTGII TLLG ++E +K KK Sbjct: 243 GESDQVRKSVDKDPMLLSGTHVMEGSGRMLVTAVGVNSQTGIIFTLLGAGGEEEEKKDKK 302 Query: 301 GKKQG---------------------------------VPENRNKAKTQDGVA-LEIQPL 326 G K+G V +++KAK QDG A +E+QPL Sbjct: 303 GVKKGDGLQLPAADGAAASNAADSANASLVNGKMQDGNVDASQSKAKQQDGAAAMEMQPL 362 Query: 327 NSQEGIDNEEKDKKAVKVPKKEKSVLQGKLTRLAVQIGKAGLLMSALTVFILILYFVIDN 386 S EG D + D+K + KKEKSVLQGKLT+LAVQIGKAGL+MSA+TV IL+LYF +D Sbjct: 363 KSAEGGDAD--DRKKASMHKKEKSVLQGKLTKLAVQIGKAGLVMSAITVIILVLYFTVDT 420 Query: 387 FVINRRPWLPECTPIYIQYFVKFFIIGITVLVVAVPEGLPLAVTISLAYSVKKMMKDNNL 446 FV+N++PWLPECTP+Y+QYFVKFFIIG+TVLVVAVPEGLPLAVTISLAYSVKKMMKDNNL Sbjct: 421 FVVNKKPWLPECTPVYVQYFVKFFIIGVTVLVVAVPEGLPLAVTISLAYSVKKMMKDNNL 480 Query: 447 VRHLDACETMGNATAICSDKTGTLTMNRMTVVQAYIGGIHYRQIPSPDVFLPKVLDLIVN 506 VRHLDACETMGNATAICSDKTGTLT NRMTVVQAY+G +HY++IP P K ++L++N Sbjct: 481 VRHLDACETMGNATAICSDKTGTLTTNRMTVVQAYVGDVHYKEIPDPSSINTKTMELLIN 540 Query: 507 GISINSAYTSKILPPEKEGGLPRQVGNKTECALLGFVTDLKQDYQAVRNEVPEEKLYKVY 566 I+INSAYT+KILPPEKEG LPRQVGNKTEC LLGFV DLKQDY+ VR+++PEEKLYKVY Sbjct: 541 AIAINSAYTTKILPPEKEGALPRQVGNKTECGLLGFVLDLKQDYEPVRSQMPEEKLYKVY 600 Query: 567 TFNSVRKSMSTVIRNPNGGFRMYSKGASEIILRKCNRILDRKGEAVPFKNKDRDDMVRTV 626 TFNSVRKSMSTVI+ P+ FRMYSKGASEI+L+KC +IL+ GE F+ +DRD+MV+ V Sbjct: 601 TFNSVRKSMSTVIKLPDESFRMYSKGASEIVLKKCCKILNGAGEPRVFRPRDRDEMVKKV 660 Query: 627 IEPMACDGLRTICIAYRDFDDT-EPSWDNENEILTELTCIAVVGIEDPVRPEVPDAIAKC 685 IEPMACDGLRTIC+AYRDF + EP WDNEN+IL ELTCI VVGIEDPVRPEVP+AI KC Sbjct: 661 IEPMACDGLRTICVAYRDFPSSPEPDWDNENDILNELTCICVVGIEDPVRPEVPEAIRKC 720 Query: 686 KQAGITVRMVTGDNINTARAIATKCGILTPGDDFLCLEGKEFNRLIRNEKGEVEQEKLDK 745 ++AGITVRMVTGDNINTARAIA KCGI+ PG+DFLCLEGKEFNR IRNEKGE+EQE++DK Sbjct: 721 QRAGITVRMVTGDNINTARAIAIKCGIIHPGEDFLCLEGKEFNRRIRNEKGEIEQERIDK 780 Query: 746 IWPKLRVLARSSPTDKHTLVKGIIDSTVGEHRQVVAVTGDGTNDGPALKKADVGFAMGIA 805 IWPKLRVLARSSPTDKHTLVKGIIDST E RQVVAVTGDGTNDGPALKKADVGFAMGIA Sbjct: 781 IWPKLRVLARSSPTDKHTLVKGIIDSTHTEQRQVVAVTGDGTNDGPALKKADVGFAMGIA 840 Query: 806 GTDVAKEASDIILTDDNFTSIVKAVMWGRNVYDSISKFLQFQLTVNVVAVIVAFTGACIT 865 GTDVAKEASDIILTDDNF+SIVKAVMWGRNVYDSISKFLQFQLTVNVVAVIVAFTGACIT Sbjct: 841 GTDVAKEASDIILTDDNFSSIVKAVMWGRNVYDSISKFLQFQLTVNVVAVIVAFTGACIT 900 Query: 866 QDSPLKAVQMLWVNLIMDTFASLALATEPPTESLLKRRPYGRNKPLISRTMMKNILGHAF 925 QDSPLKAVQMLWVNLIMDTFASLALATEPPTE+LL R+PYGRNKPLISRTMMKNILGHA Sbjct: 901 QDSPLKAVQMLWVNLIMDTFASLALATEPPTETLLLRKPYGRNKPLISRTMMKNILGHAV 960 Query: 926 YQLIVIFILVFAGEKFFDIDSGRKAPLHSPPSQHYTIVFNTFVLMQLFNEINSRKIHGEK 985 YQL +IF L+F GEK F IDSGR APLHSPPS+HYTI+FNTFV+MQLFNEIN+RKIHGE+ Sbjct: 961 YQLALIFTLLFVGEKMFQIDSGRNAPLHSPPSEHYTIIFNTFVMMQLFNEINARKIHGER 1020 Query: 986 NVFSGIYRNIIFCSVVLGTFICQIFIVEFGGKPFSCTSLSLSQWLWCLFIGIGELLWGQF 1045 NVF GI+RN IFC++VLGTF QI IV+FGGKPFSC+ L L QW+WC+FIG+GEL+WGQ Sbjct: 1021 NVFDGIFRNPIFCTIVLGTFAIQIVIVQFGGKPFSCSPLQLDQWMWCIFIGLGELVWGQV 1080 Query: 1046 ISAIPTRSLKFLKEAGHGTTKEEITKDA--EGLDEIDHAEMELRRGQILWFRGLNRIQTQ 1103 I+ IPT LKFLKEAG T KEEI ++ E ++EIDHAE ELRRGQILWFRGLNRIQTQ Sbjct: 1081 IATIPTSRLKFLKEAGRLTQKEEIPEEELNEDVEEIDHAERELRRGQILWFRGLNRIQTQ 1140 Query: 1104 IKVVKAFHSSLHESIQKPYNQKSIHSFMTHPEFAIEEELPRTPLLDEEE-------EENP 1156 I+VVKAF SSL+E ++KP ++ SIH+FM HPEF IE+ P PL+D+ + ++N Sbjct: 1141 IRVVKAFRSSLYEGLEKPESRTSIHNFMAHPEFRIEDSQPHIPLIDDTDLEEDAALKQNS 1200 Query: 1157 DKASKFGTRVLLLDGEVTPYANTNNNAVDCNQVQLPQSDSSLQSLETSV 1205 S +D + +T+ +A + S + SLETS+ Sbjct: 1201 SPPSSLNKNNSAIDSGINLTTDTSKSATSSS------PGSPIHSLETSL 1243 >gi|48255949 plasma membrane calcium ATPase 2 isoform 2 [Homo sapiens] Length = 1198 Score = 1769 bits (4581), Expect = 0.0 Identities = 895/1216 (73%), Positives = 1015/1216 (83%), Gaps = 32/1216 (2%) Query: 1 MTNPSDRVLPANSMAESREGDFGCTVMELRKLMELRSRDALTQINVHYGGVQNLCSRLKT 60 MTN SD S G+FGCT+ ELR LMELR +A+ +I YG + +C RLKT Sbjct: 4 MTN-SDFYSKNQRNESSHGGEFGCTMEELRSLMELRGTEAVVKIKETYGDTEAICRRLKT 62 Query: 61 SPVEGLSGNPADLEKRRQVFGHNVIPPKKPKTFLELVWEALQDVTLIILEIAAIISLVLS 120 SPVEGL G DLEKR+Q+FG N IPPKKPKTFL+LVWEALQDVTLIILEIAAIISL LS Sbjct: 63 SPVEGLPGTAPDLEKRKQIFGQNFIPPKKPKTFLQLVWEALQDVTLIILEIAAIISLGLS 122 Query: 121 FYRPAGEENELCGQVATTPEDENEAQAGWIEGAAILFSVIIVVLVTAFNDWSKEKQFRGL 180 FY P GE NE C EDE EA+AGWIEGAAIL SVI VVLVTAFNDWSKEKQFRGL Sbjct: 123 FYHPPGEGNEGCATAQGGAEDEGEAEAGWIEGAAILLSVICVVLVTAFNDWSKEKQFRGL 182 Query: 181 QCRIEQEQKFSIIRNGQLIQLPVAEIVVGDIAQVKYGDLLPADGILIQGNDLKIDESSLT 240 Q RIEQEQKF+++R GQ++Q+PVAEIVVGDIAQVKYGDLLPADG+ IQGNDLKIDESSLT Sbjct: 183 QSRIEQEQKFTVVRAGQVVQIPVAEIVVGDIAQVKYGDLLPADGLFIQGNDLKIDESSLT 242 Query: 241 GESDHVKKSLDKDPMLLSGTHVMEGSGRMVVTAVGVNSQTGIILTLLGVNEDDEGEKKKK 300 GESD V+KS+DKDPMLLSGTHVMEGSGRM+VTAVGVNSQTGII TLLG ++E +K KK Sbjct: 243 GESDQVRKSVDKDPMLLSGTHVMEGSGRMLVTAVGVNSQTGIIFTLLGAGGEEEEKKDKK 302 Query: 301 GKKQGVPENRNKAKTQDGVA-LEIQPLNSQEGIDNEEKDKKAVKVPKKEKSVLQGKLTRL 359 AK QDG A +E+QPL S EG D + D+K + KKEKSVLQGKLT+L Sbjct: 303 ------------AKQQDGAAAMEMQPLKSAEGGDAD--DRKKASMHKKEKSVLQGKLTKL 348 Query: 360 AVQIGKAGLLMSALTVFILILYFVIDNFVINRRPWLPECTPIYIQYFVKFFIIGITVLVV 419 AVQIGKAGL+MSA+TV IL+LYF +D FV+N++PWLPECTP+Y+QYFVKFFIIG+TVLVV Sbjct: 349 AVQIGKAGLVMSAITVIILVLYFTVDTFVVNKKPWLPECTPVYVQYFVKFFIIGVTVLVV 408 Query: 420 AVPEGLPLAVTISLAYSVKKMMKDNNLVRHLDACETMGNATAICSDKTGTLTMNRMTVVQ 479 AVPEGLPLAVTISLAYSVKKMMKDNNLVRHLDACETMGNATAICSDKTGTLT NRMTVVQ Sbjct: 409 AVPEGLPLAVTISLAYSVKKMMKDNNLVRHLDACETMGNATAICSDKTGTLTTNRMTVVQ 468 Query: 480 AYIGGIHYRQIPSPDVFLPKVLDLIVNGISINSAYTSKILPPEKEGGLPRQVGNKTECAL 539 AY+G +HY++IP P K ++L++N I+INSAYT+KILPPEKEG LPRQVGNKTEC L Sbjct: 469 AYVGDVHYKEIPDPSSINTKTMELLINAIAINSAYTTKILPPEKEGALPRQVGNKTECGL 528 Query: 540 LGFVTDLKQDYQAVRNEVPEEKLYKVYTFNSVRKSMSTVIRNPNGGFRMYSKGASEIILR 599 LGFV DLKQDY+ VR+++PEEKLYKVYTFNSVRKSMSTVI+ P+ FRMYSKGASEI+L+ Sbjct: 529 LGFVLDLKQDYEPVRSQMPEEKLYKVYTFNSVRKSMSTVIKLPDESFRMYSKGASEIVLK 588 Query: 600 KCNRILDRKGEAVPFKNKDRDDMVRTVIEPMACDGLRTICIAYRDFDDT-EPSWDNENEI 658 KC +IL+ GE F+ +DRD+MV+ VIEPMACDGLRTIC+AYRDF + EP WDNEN+I Sbjct: 589 KCCKILNGAGEPRVFRPRDRDEMVKKVIEPMACDGLRTICVAYRDFPSSPEPDWDNENDI 648 Query: 659 LTELTCIAVVGIEDPVRPEVPDAIAKCKQAGITVRMVTGDNINTARAIATKCGILTPGDD 718 L ELTCI VVGIEDPVRPEVP+AI KC++AGITVRMVTGDNINTARAIA KCGI+ PG+D Sbjct: 649 LNELTCICVVGIEDPVRPEVPEAIRKCQRAGITVRMVTGDNINTARAIAIKCGIIHPGED 708 Query: 719 FLCLEGKEFNRLIRNEKGEVEQEKLDKIWPKLRVLARSSPTDKHTLVKGIIDSTVGEHRQ 778 FLCLEGKEFNR IRNEKGE+EQE++DKIWPKLRVLARSSPTDKHTLVKGIIDST E RQ Sbjct: 709 FLCLEGKEFNRRIRNEKGEIEQERIDKIWPKLRVLARSSPTDKHTLVKGIIDSTHTEQRQ 768 Query: 779 VVAVTGDGTNDGPALKKADVGFAMGIAGTDVAKEASDIILTDDNFTSIVKAVMWGRNVYD 838 VVAVTGDGTNDGPALKKADVGFAMGIAGTDVAKEASDIILTDDNF+SIVKAVMWGRNVYD Sbjct: 769 VVAVTGDGTNDGPALKKADVGFAMGIAGTDVAKEASDIILTDDNFSSIVKAVMWGRNVYD 828 Query: 839 SISKFLQFQLTVNVVAVIVAFTGACITQDSPLKAVQMLWVNLIMDTFASLALATEPPTES 898 SISKFLQFQLTVNVVAVIVAFTGACITQDSPLKAVQMLWVNLIMDTFASLALATEPPTE+ Sbjct: 829 SISKFLQFQLTVNVVAVIVAFTGACITQDSPLKAVQMLWVNLIMDTFASLALATEPPTET 888 Query: 899 LLKRRPYGRNKPLISRTMMKNILGHAFYQLIVIFILVFAGEKFFDIDSGRKAPLHSPPSQ 958 LL R+PYGRNKPLISRTMMKNILGHA YQL +IF L+F GEK F IDSGR APLHSPPS+ Sbjct: 889 LLLRKPYGRNKPLISRTMMKNILGHAVYQLALIFTLLFVGEKMFQIDSGRNAPLHSPPSE 948 Query: 959 HYTIVFNTFVLMQLFNEINSRKIHGEKNVFSGIYRNIIFCSVVLGTFICQIFIVEFGGKP 1018 HYTI+FNTFV+MQLFNEIN+RKIHGE+NVF GI+RN IFC++VLGTF QI IV+FGGKP Sbjct: 949 HYTIIFNTFVMMQLFNEINARKIHGERNVFDGIFRNPIFCTIVLGTFAIQIVIVQFGGKP 1008 Query: 1019 FSCTSLSLSQWLWCLFIGIGELLWGQFISAIPTRSLKFLKEAGHGTTKEEITKDA--EGL 1076 FSC+ L L QW+WC+FIG+GEL+WGQ I+ IPT LKFLKEAG T KEEI ++ E + Sbjct: 1009 FSCSPLQLDQWMWCIFIGLGELVWGQVIATIPTSRLKFLKEAGRLTQKEEIPEEELNEDV 1068 Query: 1077 DEIDHAEMELRRGQILWFRGLNRIQTQIKVVKAFHSSLHESIQKPYNQKSIHSFMTHPEF 1136 +EIDHAE ELRRGQILWFRGLNRIQTQI+VVKAF SSL+E ++KP ++ SIH+FM HPEF Sbjct: 1069 EEIDHAERELRRGQILWFRGLNRIQTQIRVVKAFRSSLYEGLEKPESRTSIHNFMAHPEF 1128 Query: 1137 AIEEELPRTPLLDEEE-------EENPDKASKFGTRVLLLDGEVTPYANTNNNAVDCNQV 1189 IE+ P PL+D+ + ++N S +D + +T+ +A + Sbjct: 1129 RIEDSQPHIPLIDDTDLEEDAALKQNSSPPSSLNKNNSAIDSGINLTTDTSKSATSSS-- 1186 Query: 1190 QLPQSDSSLQSLETSV 1205 S + SLETS+ Sbjct: 1187 ----PGSPIHSLETSL 1198 >gi|48255953 plasma membrane calcium ATPase 3 isoform 3a [Homo sapiens] Length = 1173 Score = 1757 bits (4550), Expect = 0.0 Identities = 873/1100 (79%), Positives = 972/1100 (88%), Gaps = 6/1100 (0%) Query: 20 GDFGCTVMELRKLMELRSRDALTQINVHYGGVQNLCSRLKTSPVEGLSGNPADLEKRRQV 79 G FGCT+ ELR LMELR +AL +I YG V LC RLKTSP EGL+ N DLEKRRQ+ Sbjct: 25 GGFGCTLAELRTLMELRGAEALQKIEEAYGDVSGLCRRLKTSPTEGLADNTNDLEKRRQI 84 Query: 80 FGHNVIPPKKPKTFLELVWEALQDVTLIILEIAAIISLVLSFYRPAGEENELCGQVATTP 139 +G N IPPK+PKTFL+LVWEALQDVTLIILE+AAI+SL LSFY P GEE+E CG V+ Sbjct: 85 YGQNFIPPKQPKTFLQLVWEALQDVTLIILEVAAIVSLGLSFYAPPGEESEACGNVSGGA 144 Query: 140 EDENEAQAGWIEGAAILFSVIIVVLVTAFNDWSKEKQFRGLQCRIEQEQKFSIIRNGQLI 199 EDE EA+AGWIEGAAIL SVI VVLVTAFNDWSKEKQFRGLQ RIEQEQKF++IRNGQL+ Sbjct: 145 EDEGEAEAGWIEGAAILLSVICVVLVTAFNDWSKEKQFRGLQSRIEQEQKFTVIRNGQLL 204 Query: 200 QLPVAEIVVGDIAQVKYGDLLPADGILIQGNDLKIDESSLTGESDHVKKSLDKDPMLLSG 259 Q+PVA +VVGDIAQVKYGDLLPADG+LIQ NDLKIDESSLTGESDHV+KS DKDPMLLSG Sbjct: 205 QVPVAALVVGDIAQVKYGDLLPADGVLIQANDLKIDESSLTGESDHVRKSADKDPMLLSG 264 Query: 260 THVMEGSGRMVVTAVGVNSQTGIILTLLGVNEDDEGEKKKKGKKQ--GVPENRNKAKTQD 317 THVMEGSGRMVVTAVGVNSQTGII TLLG ++E +K KKGK+Q + ++ KAK QD Sbjct: 265 THVMEGSGRMVVTAVGVNSQTGIIFTLLGAGGEEEEKKDKKGKQQDGAMESSQTKAKKQD 324 Query: 318 G-VALEIQPLNSQEGIDNEEKDKKAVKVPKKEKSVLQGKLTRLAVQIGKAGLLMSALTVF 376 G VA+E+QPL S EG + EE++KK PKKEKSVLQGKLT+LAVQIGKAGL+MSA+TV Sbjct: 325 GAVAMEMQPLKSAEGGEMEEREKKKANAPKKEKSVLQGKLTKLAVQIGKAGLVMSAITVI 384 Query: 377 ILILYFVIDNFVINRRPWLPECTPIYIQYFVKFFIIGITVLVVAVPEGLPLAVTISLAYS 436 IL+LYFVI+ FV+ R WL ECTP+Y+QYFVKFFIIG+TVLVVAVPEGLPLAVTISLAYS Sbjct: 385 ILVLYFVIETFVVEGRTWLAECTPVYVQYFVKFFIIGVTVLVVAVPEGLPLAVTISLAYS 444 Query: 437 VKKMMKDNNLVRHLDACETMGNATAICSDKTGTLTMNRMTVVQAYIGGIHYRQIPSPDVF 496 VKKMMKDNNLVRHLDACETMGNATAICSDKTGTLT NRMTVVQ+Y+G HY++IP+P Sbjct: 445 VKKMMKDNNLVRHLDACETMGNATAICSDKTGTLTTNRMTVVQSYLGDTHYKEIPAPSAL 504 Query: 497 LPKVLDLIVNGISINSAYTSKILPPEKEGGLPRQVGNKTECALLGFVTDLKQDYQAVRNE 556 PK+LDL+V+ ISINSAYT+KILPPEKEG LPRQVGNKTECALLGFV DLK+D+Q VR + Sbjct: 505 TPKILDLLVHAISINSAYTTKILPPEKEGALPRQVGNKTECALLGFVLDLKRDFQPVREQ 564 Query: 557 VPEEKLYKVYTFNSVRKSMSTVIRNPNGGFRMYSKGASEIILRKCNRILDRKGEAVPFKN 616 +PE+KLYKVYTFNSVRKSMSTVIR P+GGFR++SKGASEI+L+KC IL+ GE F+ Sbjct: 565 IPEDKLYKVYTFNSVRKSMSTVIRMPDGGFRLFSKGASEILLKKCTNILNSNGELRGFRP 624 Query: 617 KDRDDMVRTVIEPMACDGLRTICIAYRDFD-DTEPSWDNENEILTELTCIAVVGIEDPVR 675 +DRDDMVR +IEPMACDGLRTICIAYRDF EP WDNENE++ +LTCIAVVGIEDPVR Sbjct: 625 RDRDDMVRKIIEPMACDGLRTICIAYRDFSAGQEPDWDNENEVVGDLTCIAVVGIEDPVR 684 Query: 676 PEVPDAIAKCKQAGITVRMVTGDNINTARAIATKCGILTPGDDFLCLEGKEFNRLIRNEK 735 PEVP+AI KC++AGITVRMVTGDNINTARAIA KCGI+ PG+DFLCLEGKEFNR IRNEK Sbjct: 685 PEVPEAIRKCQRAGITVRMVTGDNINTARAIAAKCGIIQPGEDFLCLEGKEFNRRIRNEK 744 Query: 736 GEVEQEKLDKIWPKLRVLARSSPTDKHTLVKGIIDSTVGEHRQVVAVTGDGTNDGPALKK 795 GE+EQE+LDK+WPKLRVLARSSPTDKHTLVKGIIDST GE RQVVAVTGDGTNDGPALKK Sbjct: 745 GEIEQERLDKVWPKLRVLARSSPTDKHTLVKGIIDSTTGEQRQVVAVTGDGTNDGPALKK 804 Query: 796 ADVGFAMGIAGTDVAKEASDIILTDDNFTSIVKAVMWGRNVYDSISKFLQFQLTVNVVAV 855 ADVGFAMGIAGTDVAKEASDIILTDDNFTSIVKAVMWGRNVYDSISKFLQFQLTVNVVAV Sbjct: 805 ADVGFAMGIAGTDVAKEASDIILTDDNFTSIVKAVMWGRNVYDSISKFLQFQLTVNVVAV 864 Query: 856 IVAFTGACITQDSPLKAVQMLWVNLIMDTFASLALATEPPTESLLKRRPYGRNKPLISRT 915 IVAFTGACITQDSPLKAVQMLWVNLIMDTFASLALATEPPTESLL R+PYGR+KPLISRT Sbjct: 865 IVAFTGACITQDSPLKAVQMLWVNLIMDTFASLALATEPPTESLLLRKPYGRDKPLISRT 924 Query: 916 MMKNILGHAFYQLIVIFILVFAGEKFFDIDSGRKAPLHSPPSQHYTIVFNTFVLMQLFNE 975 MMKNILGHA YQL +IF L+F GE FFDIDSGR APLHSPPS+HYTI+FNTFV+MQLFNE Sbjct: 925 MMKNILGHAVYQLAIIFTLLFVGELFFDIDSGRNAPLHSPPSEHYTIIFNTFVMMQLFNE 984 Query: 976 INSRKIHGEKNVFSGIYRNIIFCSVVLGTFICQIFIVEFGGKPFSCTSLSLSQWLWCLFI 1035 IN+RKIHGE+NVF GI+ N IFC++VLGTF QI IV+FGGKPFSC+ LS QWLWCLF+ Sbjct: 985 INARKIHGERNVFDGIFSNPIFCTIVLGTFGIQIVIVQFGGKPFSCSPLSTEQWLWCLFV 1044 Query: 1036 GIGELLWGQFISAIPTRSLKFLKEAGHGTTKEEITKD--AEGLDEIDHAEMELRRGQILW 1093 G+GEL+WGQ I+ IPT LK LKEAGHG K+E+T + AEG +EIDHAE ELRRGQILW Sbjct: 1045 GVGELVWGQVIATIPTSQLKCLKEAGHGPGKDEMTDEELAEGEEEIDHAERELRRGQILW 1104 Query: 1094 FRGLNRIQTQIKVVKAFHSS 1113 FRGLNRIQTQ++VV F S Sbjct: 1105 FRGLNRIQTQMEVVSTFKRS 1124 >gi|28373103 ATPase, Ca++ transporting, ubiquitous isoform a [Homo sapiens] Length = 999 Score = 300 bits (767), Expect = 7e-81 Identities = 266/931 (28%), Positives = 431/931 (46%), Gaps = 175/931 (18%) Query: 69 NPADLEKRRQVFGHNVIPPKKPKTFLELVWEALQDVTLIILEIAAIISLVLSFYRPAGEE 128 +PA + R+ +G N +P ++ K+ ELV E +D+ + IL +AA++S VL+++ Sbjct: 25 SPAQVTGARERYGPNELPSEEGKSLWELVLEQFEDLLVRILLLAALVSFVLAWF------ 78 Query: 129 NELCGQVATTPEDENEAQAGWIEGAAILFSVIIVVLVTAFNDWSKEKQFRGLQCRIEQEQ 188 E+ E ++E I+ ++ +V + + + E L+ E E Sbjct: 79 -----------EEGEETTTAFVEPLVIMLILVANAIVGVWQERNAESAIEALK---EYEP 124 Query: 189 KFS-IIRNGQ--LIQLPVAEIVVGDIAQVKYGDLLPADGILIQ--GNDLKIDESSLTGES 243 + +IR+ + + ++ +IV GDI +V GD +PAD LI+ L++D+S LTGES Sbjct: 125 EMGKVIRSDRKGVQRIRARDIVPGDIVEVAVGDKVPADLRLIEIKSTTLRVDQSILTGES 184 Query: 244 DHVKK-----------SLDKDPMLLSGTHVMEGSGRMVVTAVGVNSQTGIILTLLGVNED 292 V K + DK ML SGT++ G AVGV TG+ T LG Sbjct: 185 VSVTKHTEAIPDPRAVNQDKKNMLFSGTNITSGK------AVGVAVATGLH-TELG---- 233 Query: 293 DEGEKKKKGKKQGVPENRNKAKTQDGVALEIQPLNSQEGIDNEEKDKKAVKVPKKEKSVL 352 K + + + E++ L Sbjct: 234 --------------------------------------------KIRSQMAAVEPERTPL 249 Query: 353 QGKLTRLAVQIGKAGLLMSALTVFILILYFVIDNFVINRRPWLPECTPIYIQYFVKFFII 412 Q KL Q+ A + + + V+++ + D P +++ V +F I Sbjct: 250 QRKLDEFGRQLSHA-ISVICVAVWVINIGHFAD----------PAHGGSWLRGAVYYFKI 298 Query: 413 GITVLVVAVPEGLPLAVTISLAYSVKKMMKDNNLVRHLDACETMGNATAICSDKTGTLTM 472 + + V A+PEGLP +T LA ++M + N +VR L + ET+G + ICSDKTGTLT Sbjct: 299 AVALAVAAIPEGLPAVITTCLALGTRRMARKNAIVRSLPSVETLGCTSVICSDKTGTLTT 358 Query: 473 NRMTVVQAYIGG--------IHYRQIPSPDVFLPK-------------VLDLIVNGISIN 511 N+M+V + ++ +H I S + P+ D +V +I Sbjct: 359 NQMSVCRMFVVAEADAGSCLLHEFTI-SGTTYTPEGEVRQGDQPVRCGQFDGLVELATIC 417 Query: 512 SAYTSKILPPEKEGGLPRQVGNKTECALLGFVTDLK---QDYQAVR--------NEVPEE 560 + L + G+ +VG TE AL V + D QA+ N V ++ Sbjct: 418 ALCNDSALDYNEAKGVYEKVGEATETALTCLVEKMNVFDTDLQALSRVERAGACNTVIKQ 477 Query: 561 KLYKVYT--FNSVRKSMSTVIR----NPNG-GFRMYSKGASEIILRKCNRILDRKGE-AV 612 + K +T F+ RKSMS +P G G +M+ KGA E ++ +C+ + R G Sbjct: 478 LMRKEFTLEFSRDRKSMSVYCTPTRPHPTGQGSKMFVKGAPESVIERCSSV--RVGSRTA 535 Query: 613 PFKNKDRDDMVRTVIE-PMACDGLRTICIAYRDFDDTEPSWDNEN-----EILTELTCIA 666 P R+ ++ + + D LR + +A RD + + ++ + T+LT + Sbjct: 536 PLTPTSREQILAKIRDWGSGSDTLRCLALATRDAPPRKEDMELDDCSKFVQYETDLTFVG 595 Query: 667 VVGIEDPVRPEVPDAIAKCKQAGITVRMVTGDNINTARAIATKCGILTPGDDFL--CLEG 724 VG+ DP RPEV I +C QAGI V M+TGDN TA AI + GI +D G Sbjct: 596 CVGMLDPPRPEVAACITRCYQAGIRVVMITGDNKGTAVAICRRLGIFGDTEDVAGKAYTG 655 Query: 725 KEFNRLIRNEKGEVEQEKLDKIWPKLRVLARSSPTDKHTLVKGIIDSTVGEHRQVVAVTG 784 +EF+ ++ E+ + R AR P K +V+ + ++ A+TG Sbjct: 656 REFD--------DLSPEQQRQACRTARCFARVEPAHKSRIVENL-----QSFNEITAMTG 702 Query: 785 DGTNDGPALKKADVGFAMGIAGTDVAKEASDIILTDDNFTSIVKAVMWGRNVYDSISKFL 844 DG ND PALKKA++G AMG +GT VAK A++++L+DDNF SIV AV GR +Y ++ +F+ Sbjct: 703 DGVNDAPALKKAEIGIAMG-SGTAVAKSAAEMVLSDDNFASIVAAVEEGRAIYSNMKQFI 761 Query: 845 QFQLTVNVVAVIVAFTGACITQDSPLKAVQMLWVNLIMDTFASLALATEPPTESLLKRRP 904 ++ ++ NV V+ F A + L VQ+LWVNL+ D + AL PP ++++ P Sbjct: 762 RYLISSNVGEVVCIFLTAILGLPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMEKLP 821 Query: 905 YGRNKPLISRTMMKNILGHAFYQLIVIFILV 935 + LIS G F++ + I + V Sbjct: 822 RSPREALIS--------GWLFFRYLAIGVYV 844 >gi|28373115 ATPase, Ca++ transporting, ubiquitous isoform c [Homo sapiens] Length = 1029 Score = 300 bits (767), Expect = 7e-81 Identities = 266/931 (28%), Positives = 431/931 (46%), Gaps = 175/931 (18%) Query: 69 NPADLEKRRQVFGHNVIPPKKPKTFLELVWEALQDVTLIILEIAAIISLVLSFYRPAGEE 128 +PA + R+ +G N +P ++ K+ ELV E +D+ + IL +AA++S VL+++ Sbjct: 25 SPAQVTGARERYGPNELPSEEGKSLWELVLEQFEDLLVRILLLAALVSFVLAWF------ 78 Query: 129 NELCGQVATTPEDENEAQAGWIEGAAILFSVIIVVLVTAFNDWSKEKQFRGLQCRIEQEQ 188 E+ E ++E I+ ++ +V + + + E L+ E E Sbjct: 79 -----------EEGEETTTAFVEPLVIMLILVANAIVGVWQERNAESAIEALK---EYEP 124 Query: 189 KFS-IIRNGQ--LIQLPVAEIVVGDIAQVKYGDLLPADGILIQ--GNDLKIDESSLTGES 243 + +IR+ + + ++ +IV GDI +V GD +PAD LI+ L++D+S LTGES Sbjct: 125 EMGKVIRSDRKGVQRIRARDIVPGDIVEVAVGDKVPADLRLIEIKSTTLRVDQSILTGES 184 Query: 244 DHVKK-----------SLDKDPMLLSGTHVMEGSGRMVVTAVGVNSQTGIILTLLGVNED 292 V K + DK ML SGT++ G AVGV TG+ T LG Sbjct: 185 VSVTKHTEAIPDPRAVNQDKKNMLFSGTNITSGK------AVGVAVATGLH-TELG---- 233 Query: 293 DEGEKKKKGKKQGVPENRNKAKTQDGVALEIQPLNSQEGIDNEEKDKKAVKVPKKEKSVL 352 K + + + E++ L Sbjct: 234 --------------------------------------------KIRSQMAAVEPERTPL 249 Query: 353 QGKLTRLAVQIGKAGLLMSALTVFILILYFVIDNFVINRRPWLPECTPIYIQYFVKFFII 412 Q KL Q+ A + + + V+++ + D P +++ V +F I Sbjct: 250 QRKLDEFGRQLSHA-ISVICVAVWVINIGHFAD----------PAHGGSWLRGAVYYFKI 298 Query: 413 GITVLVVAVPEGLPLAVTISLAYSVKKMMKDNNLVRHLDACETMGNATAICSDKTGTLTM 472 + + V A+PEGLP +T LA ++M + N +VR L + ET+G + ICSDKTGTLT Sbjct: 299 AVALAVAAIPEGLPAVITTCLALGTRRMARKNAIVRSLPSVETLGCTSVICSDKTGTLTT 358 Query: 473 NRMTVVQAYIGG--------IHYRQIPSPDVFLPK-------------VLDLIVNGISIN 511 N+M+V + ++ +H I S + P+ D +V +I Sbjct: 359 NQMSVCRMFVVAEADAGSCLLHEFTI-SGTTYTPEGEVRQGDQPVRCGQFDGLVELATIC 417 Query: 512 SAYTSKILPPEKEGGLPRQVGNKTECALLGFVTDLK---QDYQAVR--------NEVPEE 560 + L + G+ +VG TE AL V + D QA+ N V ++ Sbjct: 418 ALCNDSALDYNEAKGVYEKVGEATETALTCLVEKMNVFDTDLQALSRVERAGACNTVIKQ 477 Query: 561 KLYKVYT--FNSVRKSMSTVIR----NPNG-GFRMYSKGASEIILRKCNRILDRKGE-AV 612 + K +T F+ RKSMS +P G G +M+ KGA E ++ +C+ + R G Sbjct: 478 LMRKEFTLEFSRDRKSMSVYCTPTRPHPTGQGSKMFVKGAPESVIERCSSV--RVGSRTA 535 Query: 613 PFKNKDRDDMVRTVIE-PMACDGLRTICIAYRDFDDTEPSWDNEN-----EILTELTCIA 666 P R+ ++ + + D LR + +A RD + + ++ + T+LT + Sbjct: 536 PLTPTSREQILAKIRDWGSGSDTLRCLALATRDAPPRKEDMELDDCSKFVQYETDLTFVG 595 Query: 667 VVGIEDPVRPEVPDAIAKCKQAGITVRMVTGDNINTARAIATKCGILTPGDDFL--CLEG 724 VG+ DP RPEV I +C QAGI V M+TGDN TA AI + GI +D G Sbjct: 596 CVGMLDPPRPEVAACITRCYQAGIRVVMITGDNKGTAVAICRRLGIFGDTEDVAGKAYTG 655 Query: 725 KEFNRLIRNEKGEVEQEKLDKIWPKLRVLARSSPTDKHTLVKGIIDSTVGEHRQVVAVTG 784 +EF+ ++ E+ + R AR P K +V+ + ++ A+TG Sbjct: 656 REFD--------DLSPEQQRQACRTARCFARVEPAHKSRIVENL-----QSFNEITAMTG 702 Query: 785 DGTNDGPALKKADVGFAMGIAGTDVAKEASDIILTDDNFTSIVKAVMWGRNVYDSISKFL 844 DG ND PALKKA++G AMG +GT VAK A++++L+DDNF SIV AV GR +Y ++ +F+ Sbjct: 703 DGVNDAPALKKAEIGIAMG-SGTAVAKSAAEMVLSDDNFASIVAAVEEGRAIYSNMKQFI 761 Query: 845 QFQLTVNVVAVIVAFTGACITQDSPLKAVQMLWVNLIMDTFASLALATEPPTESLLKRRP 904 ++ ++ NV V+ F A + L VQ+LWVNL+ D + AL PP ++++ P Sbjct: 762 RYLISSNVGEVVCIFLTAILGLPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMEKLP 821 Query: 905 YGRNKPLISRTMMKNILGHAFYQLIVIFILV 935 + LIS G F++ + I + V Sbjct: 822 RSPREALIS--------GWLFFRYLAIGVYV 844 >gi|28373113 ATPase, Ca++ transporting, ubiquitous isoform f [Homo sapiens] Length = 998 Score = 300 bits (767), Expect = 7e-81 Identities = 266/931 (28%), Positives = 431/931 (46%), Gaps = 175/931 (18%) Query: 69 NPADLEKRRQVFGHNVIPPKKPKTFLELVWEALQDVTLIILEIAAIISLVLSFYRPAGEE 128 +PA + R+ +G N +P ++ K+ ELV E +D+ + IL +AA++S VL+++ Sbjct: 25 SPAQVTGARERYGPNELPSEEGKSLWELVLEQFEDLLVRILLLAALVSFVLAWF------ 78 Query: 129 NELCGQVATTPEDENEAQAGWIEGAAILFSVIIVVLVTAFNDWSKEKQFRGLQCRIEQEQ 188 E+ E ++E I+ ++ +V + + + E L+ E E Sbjct: 79 -----------EEGEETTTAFVEPLVIMLILVANAIVGVWQERNAESAIEALK---EYEP 124 Query: 189 KFS-IIRNGQ--LIQLPVAEIVVGDIAQVKYGDLLPADGILIQ--GNDLKIDESSLTGES 243 + +IR+ + + ++ +IV GDI +V GD +PAD LI+ L++D+S LTGES Sbjct: 125 EMGKVIRSDRKGVQRIRARDIVPGDIVEVAVGDKVPADLRLIEIKSTTLRVDQSILTGES 184 Query: 244 DHVKK-----------SLDKDPMLLSGTHVMEGSGRMVVTAVGVNSQTGIILTLLGVNED 292 V K + DK ML SGT++ G AVGV TG+ T LG Sbjct: 185 VSVTKHTEAIPDPRAVNQDKKNMLFSGTNITSGK------AVGVAVATGLH-TELG---- 233 Query: 293 DEGEKKKKGKKQGVPENRNKAKTQDGVALEIQPLNSQEGIDNEEKDKKAVKVPKKEKSVL 352 K + + + E++ L Sbjct: 234 --------------------------------------------KIRSQMAAVEPERTPL 249 Query: 353 QGKLTRLAVQIGKAGLLMSALTVFILILYFVIDNFVINRRPWLPECTPIYIQYFVKFFII 412 Q KL Q+ A + + + V+++ + D P +++ V +F I Sbjct: 250 QRKLDEFGRQLSHA-ISVICVAVWVINIGHFAD----------PAHGGSWLRGAVYYFKI 298 Query: 413 GITVLVVAVPEGLPLAVTISLAYSVKKMMKDNNLVRHLDACETMGNATAICSDKTGTLTM 472 + + V A+PEGLP +T LA ++M + N +VR L + ET+G + ICSDKTGTLT Sbjct: 299 AVALAVAAIPEGLPAVITTCLALGTRRMARKNAIVRSLPSVETLGCTSVICSDKTGTLTT 358 Query: 473 NRMTVVQAYIGG--------IHYRQIPSPDVFLPK-------------VLDLIVNGISIN 511 N+M+V + ++ +H I S + P+ D +V +I Sbjct: 359 NQMSVCRMFVVAEADAGSCLLHEFTI-SGTTYTPEGEVRQGDQPVRCGQFDGLVELATIC 417 Query: 512 SAYTSKILPPEKEGGLPRQVGNKTECALLGFVTDLK---QDYQAVR--------NEVPEE 560 + L + G+ +VG TE AL V + D QA+ N V ++ Sbjct: 418 ALCNDSALDYNEAKGVYEKVGEATETALTCLVEKMNVFDTDLQALSRVERAGACNTVIKQ 477 Query: 561 KLYKVYT--FNSVRKSMSTVIR----NPNG-GFRMYSKGASEIILRKCNRILDRKGE-AV 612 + K +T F+ RKSMS +P G G +M+ KGA E ++ +C+ + R G Sbjct: 478 LMRKEFTLEFSRDRKSMSVYCTPTRPHPTGQGSKMFVKGAPESVIERCSSV--RVGSRTA 535 Query: 613 PFKNKDRDDMVRTVIE-PMACDGLRTICIAYRDFDDTEPSWDNEN-----EILTELTCIA 666 P R+ ++ + + D LR + +A RD + + ++ + T+LT + Sbjct: 536 PLTPTSREQILAKIRDWGSGSDTLRCLALATRDAPPRKEDMELDDCSKFVQYETDLTFVG 595 Query: 667 VVGIEDPVRPEVPDAIAKCKQAGITVRMVTGDNINTARAIATKCGILTPGDDFL--CLEG 724 VG+ DP RPEV I +C QAGI V M+TGDN TA AI + GI +D G Sbjct: 596 CVGMLDPPRPEVAACITRCYQAGIRVVMITGDNKGTAVAICRRLGIFGDTEDVAGKAYTG 655 Query: 725 KEFNRLIRNEKGEVEQEKLDKIWPKLRVLARSSPTDKHTLVKGIIDSTVGEHRQVVAVTG 784 +EF+ ++ E+ + R AR P K +V+ + ++ A+TG Sbjct: 656 REFD--------DLSPEQQRQACRTARCFARVEPAHKSRIVENL-----QSFNEITAMTG 702 Query: 785 DGTNDGPALKKADVGFAMGIAGTDVAKEASDIILTDDNFTSIVKAVMWGRNVYDSISKFL 844 DG ND PALKKA++G AMG +GT VAK A++++L+DDNF SIV AV GR +Y ++ +F+ Sbjct: 703 DGVNDAPALKKAEIGIAMG-SGTAVAKSAAEMVLSDDNFASIVAAVEEGRAIYSNMKQFI 761 Query: 845 QFQLTVNVVAVIVAFTGACITQDSPLKAVQMLWVNLIMDTFASLALATEPPTESLLKRRP 904 ++ ++ NV V+ F A + L VQ+LWVNL+ D + AL PP ++++ P Sbjct: 762 RYLISSNVGEVVCIFLTAILGLPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMEKLP 821 Query: 905 YGRNKPLISRTMMKNILGHAFYQLIVIFILV 935 + LIS G F++ + I + V Sbjct: 822 RSPREALIS--------GWLFFRYLAIGVYV 844 >gi|28373111 ATPase, Ca++ transporting, ubiquitous isoform c [Homo sapiens] Length = 1029 Score = 300 bits (767), Expect = 7e-81 Identities = 266/931 (28%), Positives = 431/931 (46%), Gaps = 175/931 (18%) Query: 69 NPADLEKRRQVFGHNVIPPKKPKTFLELVWEALQDVTLIILEIAAIISLVLSFYRPAGEE 128 +PA + R+ +G N +P ++ K+ ELV E +D+ + IL +AA++S VL+++ Sbjct: 25 SPAQVTGARERYGPNELPSEEGKSLWELVLEQFEDLLVRILLLAALVSFVLAWF------ 78 Query: 129 NELCGQVATTPEDENEAQAGWIEGAAILFSVIIVVLVTAFNDWSKEKQFRGLQCRIEQEQ 188 E+ E ++E I+ ++ +V + + + E L+ E E Sbjct: 79 -----------EEGEETTTAFVEPLVIMLILVANAIVGVWQERNAESAIEALK---EYEP 124 Query: 189 KFS-IIRNGQ--LIQLPVAEIVVGDIAQVKYGDLLPADGILIQ--GNDLKIDESSLTGES 243 + +IR+ + + ++ +IV GDI +V GD +PAD LI+ L++D+S LTGES Sbjct: 125 EMGKVIRSDRKGVQRIRARDIVPGDIVEVAVGDKVPADLRLIEIKSTTLRVDQSILTGES 184 Query: 244 DHVKK-----------SLDKDPMLLSGTHVMEGSGRMVVTAVGVNSQTGIILTLLGVNED 292 V K + DK ML SGT++ G AVGV TG+ T LG Sbjct: 185 VSVTKHTEAIPDPRAVNQDKKNMLFSGTNITSGK------AVGVAVATGLH-TELG---- 233 Query: 293 DEGEKKKKGKKQGVPENRNKAKTQDGVALEIQPLNSQEGIDNEEKDKKAVKVPKKEKSVL 352 K + + + E++ L Sbjct: 234 --------------------------------------------KIRSQMAAVEPERTPL 249 Query: 353 QGKLTRLAVQIGKAGLLMSALTVFILILYFVIDNFVINRRPWLPECTPIYIQYFVKFFII 412 Q KL Q+ A + + + V+++ + D P +++ V +F I Sbjct: 250 QRKLDEFGRQLSHA-ISVICVAVWVINIGHFAD----------PAHGGSWLRGAVYYFKI 298 Query: 413 GITVLVVAVPEGLPLAVTISLAYSVKKMMKDNNLVRHLDACETMGNATAICSDKTGTLTM 472 + + V A+PEGLP +T LA ++M + N +VR L + ET+G + ICSDKTGTLT Sbjct: 299 AVALAVAAIPEGLPAVITTCLALGTRRMARKNAIVRSLPSVETLGCTSVICSDKTGTLTT 358 Query: 473 NRMTVVQAYIGG--------IHYRQIPSPDVFLPK-------------VLDLIVNGISIN 511 N+M+V + ++ +H I S + P+ D +V +I Sbjct: 359 NQMSVCRMFVVAEADAGSCLLHEFTI-SGTTYTPEGEVRQGDQPVRCGQFDGLVELATIC 417 Query: 512 SAYTSKILPPEKEGGLPRQVGNKTECALLGFVTDLK---QDYQAVR--------NEVPEE 560 + L + G+ +VG TE AL V + D QA+ N V ++ Sbjct: 418 ALCNDSALDYNEAKGVYEKVGEATETALTCLVEKMNVFDTDLQALSRVERAGACNTVIKQ 477 Query: 561 KLYKVYT--FNSVRKSMSTVIR----NPNG-GFRMYSKGASEIILRKCNRILDRKGE-AV 612 + K +T F+ RKSMS +P G G +M+ KGA E ++ +C+ + R G Sbjct: 478 LMRKEFTLEFSRDRKSMSVYCTPTRPHPTGQGSKMFVKGAPESVIERCSSV--RVGSRTA 535 Query: 613 PFKNKDRDDMVRTVIE-PMACDGLRTICIAYRDFDDTEPSWDNEN-----EILTELTCIA 666 P R+ ++ + + D LR + +A RD + + ++ + T+LT + Sbjct: 536 PLTPTSREQILAKIRDWGSGSDTLRCLALATRDAPPRKEDMELDDCSKFVQYETDLTFVG 595 Query: 667 VVGIEDPVRPEVPDAIAKCKQAGITVRMVTGDNINTARAIATKCGILTPGDDFL--CLEG 724 VG+ DP RPEV I +C QAGI V M+TGDN TA AI + GI +D G Sbjct: 596 CVGMLDPPRPEVAACITRCYQAGIRVVMITGDNKGTAVAICRRLGIFGDTEDVAGKAYTG 655 Query: 725 KEFNRLIRNEKGEVEQEKLDKIWPKLRVLARSSPTDKHTLVKGIIDSTVGEHRQVVAVTG 784 +EF+ ++ E+ + R AR P K +V+ + ++ A+TG Sbjct: 656 REFD--------DLSPEQQRQACRTARCFARVEPAHKSRIVENL-----QSFNEITAMTG 702 Query: 785 DGTNDGPALKKADVGFAMGIAGTDVAKEASDIILTDDNFTSIVKAVMWGRNVYDSISKFL 844 DG ND PALKKA++G AMG +GT VAK A++++L+DDNF SIV AV GR +Y ++ +F+ Sbjct: 703 DGVNDAPALKKAEIGIAMG-SGTAVAKSAAEMVLSDDNFASIVAAVEEGRAIYSNMKQFI 761 Query: 845 QFQLTVNVVAVIVAFTGACITQDSPLKAVQMLWVNLIMDTFASLALATEPPTESLLKRRP 904 ++ ++ NV V+ F A + L VQ+LWVNL+ D + AL PP ++++ P Sbjct: 762 RYLISSNVGEVVCIFLTAILGLPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMEKLP 821 Query: 905 YGRNKPLISRTMMKNILGHAFYQLIVIFILV 935 + LIS G F++ + I + V Sbjct: 822 RSPREALIS--------GWLFFRYLAIGVYV 844 >gi|28373109 ATPase, Ca++ transporting, ubiquitous isoform b [Homo sapiens] Length = 1043 Score = 300 bits (767), Expect = 7e-81 Identities = 266/931 (28%), Positives = 431/931 (46%), Gaps = 175/931 (18%) Query: 69 NPADLEKRRQVFGHNVIPPKKPKTFLELVWEALQDVTLIILEIAAIISLVLSFYRPAGEE 128 +PA + R+ +G N +P ++ K+ ELV E +D+ + IL +AA++S VL+++ Sbjct: 25 SPAQVTGARERYGPNELPSEEGKSLWELVLEQFEDLLVRILLLAALVSFVLAWF------ 78 Query: 129 NELCGQVATTPEDENEAQAGWIEGAAILFSVIIVVLVTAFNDWSKEKQFRGLQCRIEQEQ 188 E+ E ++E I+ ++ +V + + + E L+ E E Sbjct: 79 -----------EEGEETTTAFVEPLVIMLILVANAIVGVWQERNAESAIEALK---EYEP 124 Query: 189 KFS-IIRNGQ--LIQLPVAEIVVGDIAQVKYGDLLPADGILIQ--GNDLKIDESSLTGES 243 + +IR+ + + ++ +IV GDI +V GD +PAD LI+ L++D+S LTGES Sbjct: 125 EMGKVIRSDRKGVQRIRARDIVPGDIVEVAVGDKVPADLRLIEIKSTTLRVDQSILTGES 184 Query: 244 DHVKK-----------SLDKDPMLLSGTHVMEGSGRMVVTAVGVNSQTGIILTLLGVNED 292 V K + DK ML SGT++ G AVGV TG+ T LG Sbjct: 185 VSVTKHTEAIPDPRAVNQDKKNMLFSGTNITSGK------AVGVAVATGLH-TELG---- 233 Query: 293 DEGEKKKKGKKQGVPENRNKAKTQDGVALEIQPLNSQEGIDNEEKDKKAVKVPKKEKSVL 352 K + + + E++ L Sbjct: 234 --------------------------------------------KIRSQMAAVEPERTPL 249 Query: 353 QGKLTRLAVQIGKAGLLMSALTVFILILYFVIDNFVINRRPWLPECTPIYIQYFVKFFII 412 Q KL Q+ A + + + V+++ + D P +++ V +F I Sbjct: 250 QRKLDEFGRQLSHA-ISVICVAVWVINIGHFAD----------PAHGGSWLRGAVYYFKI 298 Query: 413 GITVLVVAVPEGLPLAVTISLAYSVKKMMKDNNLVRHLDACETMGNATAICSDKTGTLTM 472 + + V A+PEGLP +T LA ++M + N +VR L + ET+G + ICSDKTGTLT Sbjct: 299 AVALAVAAIPEGLPAVITTCLALGTRRMARKNAIVRSLPSVETLGCTSVICSDKTGTLTT 358 Query: 473 NRMTVVQAYIGG--------IHYRQIPSPDVFLPK-------------VLDLIVNGISIN 511 N+M+V + ++ +H I S + P+ D +V +I Sbjct: 359 NQMSVCRMFVVAEADAGSCLLHEFTI-SGTTYTPEGEVRQGDQPVRCGQFDGLVELATIC 417 Query: 512 SAYTSKILPPEKEGGLPRQVGNKTECALLGFVTDLK---QDYQAVR--------NEVPEE 560 + L + G+ +VG TE AL V + D QA+ N V ++ Sbjct: 418 ALCNDSALDYNEAKGVYEKVGEATETALTCLVEKMNVFDTDLQALSRVERAGACNTVIKQ 477 Query: 561 KLYKVYT--FNSVRKSMSTVIR----NPNG-GFRMYSKGASEIILRKCNRILDRKGE-AV 612 + K +T F+ RKSMS +P G G +M+ KGA E ++ +C+ + R G Sbjct: 478 LMRKEFTLEFSRDRKSMSVYCTPTRPHPTGQGSKMFVKGAPESVIERCSSV--RVGSRTA 535 Query: 613 PFKNKDRDDMVRTVIE-PMACDGLRTICIAYRDFDDTEPSWDNEN-----EILTELTCIA 666 P R+ ++ + + D LR + +A RD + + ++ + T+LT + Sbjct: 536 PLTPTSREQILAKIRDWGSGSDTLRCLALATRDAPPRKEDMELDDCSKFVQYETDLTFVG 595 Query: 667 VVGIEDPVRPEVPDAIAKCKQAGITVRMVTGDNINTARAIATKCGILTPGDDFL--CLEG 724 VG+ DP RPEV I +C QAGI V M+TGDN TA AI + GI +D G Sbjct: 596 CVGMLDPPRPEVAACITRCYQAGIRVVMITGDNKGTAVAICRRLGIFGDTEDVAGKAYTG 655 Query: 725 KEFNRLIRNEKGEVEQEKLDKIWPKLRVLARSSPTDKHTLVKGIIDSTVGEHRQVVAVTG 784 +EF+ ++ E+ + R AR P K +V+ + ++ A+TG Sbjct: 656 REFD--------DLSPEQQRQACRTARCFARVEPAHKSRIVENL-----QSFNEITAMTG 702 Query: 785 DGTNDGPALKKADVGFAMGIAGTDVAKEASDIILTDDNFTSIVKAVMWGRNVYDSISKFL 844 DG ND PALKKA++G AMG +GT VAK A++++L+DDNF SIV AV GR +Y ++ +F+ Sbjct: 703 DGVNDAPALKKAEIGIAMG-SGTAVAKSAAEMVLSDDNFASIVAAVEEGRAIYSNMKQFI 761 Query: 845 QFQLTVNVVAVIVAFTGACITQDSPLKAVQMLWVNLIMDTFASLALATEPPTESLLKRRP 904 ++ ++ NV V+ F A + L VQ+LWVNL+ D + AL PP ++++ P Sbjct: 762 RYLISSNVGEVVCIFLTAILGLPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMEKLP 821 Query: 905 YGRNKPLISRTMMKNILGHAFYQLIVIFILV 935 + LIS G F++ + I + V Sbjct: 822 RSPREALIS--------GWLFFRYLAIGVYV 844 >gi|28373107 ATPase, Ca++ transporting, ubiquitous isoform d [Homo sapiens] Length = 1044 Score = 300 bits (767), Expect = 7e-81 Identities = 266/931 (28%), Positives = 431/931 (46%), Gaps = 175/931 (18%) Query: 69 NPADLEKRRQVFGHNVIPPKKPKTFLELVWEALQDVTLIILEIAAIISLVLSFYRPAGEE 128 +PA + R+ +G N +P ++ K+ ELV E +D+ + IL +AA++S VL+++ Sbjct: 25 SPAQVTGARERYGPNELPSEEGKSLWELVLEQFEDLLVRILLLAALVSFVLAWF------ 78 Query: 129 NELCGQVATTPEDENEAQAGWIEGAAILFSVIIVVLVTAFNDWSKEKQFRGLQCRIEQEQ 188 E+ E ++E I+ ++ +V + + + E L+ E E Sbjct: 79 -----------EEGEETTTAFVEPLVIMLILVANAIVGVWQERNAESAIEALK---EYEP 124 Query: 189 KFS-IIRNGQ--LIQLPVAEIVVGDIAQVKYGDLLPADGILIQ--GNDLKIDESSLTGES 243 + +IR+ + + ++ +IV GDI +V GD +PAD LI+ L++D+S LTGES Sbjct: 125 EMGKVIRSDRKGVQRIRARDIVPGDIVEVAVGDKVPADLRLIEIKSTTLRVDQSILTGES 184 Query: 244 DHVKK-----------SLDKDPMLLSGTHVMEGSGRMVVTAVGVNSQTGIILTLLGVNED 292 V K + DK ML SGT++ G AVGV TG+ T LG Sbjct: 185 VSVTKHTEAIPDPRAVNQDKKNMLFSGTNITSGK------AVGVAVATGLH-TELG---- 233 Query: 293 DEGEKKKKGKKQGVPENRNKAKTQDGVALEIQPLNSQEGIDNEEKDKKAVKVPKKEKSVL 352 K + + + E++ L Sbjct: 234 --------------------------------------------KIRSQMAAVEPERTPL 249 Query: 353 QGKLTRLAVQIGKAGLLMSALTVFILILYFVIDNFVINRRPWLPECTPIYIQYFVKFFII 412 Q KL Q+ A + + + V+++ + D P +++ V +F I Sbjct: 250 QRKLDEFGRQLSHA-ISVICVAVWVINIGHFAD----------PAHGGSWLRGAVYYFKI 298 Query: 413 GITVLVVAVPEGLPLAVTISLAYSVKKMMKDNNLVRHLDACETMGNATAICSDKTGTLTM 472 + + V A+PEGLP +T LA ++M + N +VR L + ET+G + ICSDKTGTLT Sbjct: 299 AVALAVAAIPEGLPAVITTCLALGTRRMARKNAIVRSLPSVETLGCTSVICSDKTGTLTT 358 Query: 473 NRMTVVQAYIGG--------IHYRQIPSPDVFLPK-------------VLDLIVNGISIN 511 N+M+V + ++ +H I S + P+ D +V +I Sbjct: 359 NQMSVCRMFVVAEADAGSCLLHEFTI-SGTTYTPEGEVRQGDQPVRCGQFDGLVELATIC 417 Query: 512 SAYTSKILPPEKEGGLPRQVGNKTECALLGFVTDLK---QDYQAVR--------NEVPEE 560 + L + G+ +VG TE AL V + D QA+ N V ++ Sbjct: 418 ALCNDSALDYNEAKGVYEKVGEATETALTCLVEKMNVFDTDLQALSRVERAGACNTVIKQ 477 Query: 561 KLYKVYT--FNSVRKSMSTVIR----NPNG-GFRMYSKGASEIILRKCNRILDRKGE-AV 612 + K +T F+ RKSMS +P G G +M+ KGA E ++ +C+ + R G Sbjct: 478 LMRKEFTLEFSRDRKSMSVYCTPTRPHPTGQGSKMFVKGAPESVIERCSSV--RVGSRTA 535 Query: 613 PFKNKDRDDMVRTVIE-PMACDGLRTICIAYRDFDDTEPSWDNEN-----EILTELTCIA 666 P R+ ++ + + D LR + +A RD + + ++ + T+LT + Sbjct: 536 PLTPTSREQILAKIRDWGSGSDTLRCLALATRDAPPRKEDMELDDCSKFVQYETDLTFVG 595 Query: 667 VVGIEDPVRPEVPDAIAKCKQAGITVRMVTGDNINTARAIATKCGILTPGDDFL--CLEG 724 VG+ DP RPEV I +C QAGI V M+TGDN TA AI + GI +D G Sbjct: 596 CVGMLDPPRPEVAACITRCYQAGIRVVMITGDNKGTAVAICRRLGIFGDTEDVAGKAYTG 655 Query: 725 KEFNRLIRNEKGEVEQEKLDKIWPKLRVLARSSPTDKHTLVKGIIDSTVGEHRQVVAVTG 784 +EF+ ++ E+ + R AR P K +V+ + ++ A+TG Sbjct: 656 REFD--------DLSPEQQRQACRTARCFARVEPAHKSRIVENL-----QSFNEITAMTG 702 Query: 785 DGTNDGPALKKADVGFAMGIAGTDVAKEASDIILTDDNFTSIVKAVMWGRNVYDSISKFL 844 DG ND PALKKA++G AMG +GT VAK A++++L+DDNF SIV AV GR +Y ++ +F+ Sbjct: 703 DGVNDAPALKKAEIGIAMG-SGTAVAKSAAEMVLSDDNFASIVAAVEEGRAIYSNMKQFI 761 Query: 845 QFQLTVNVVAVIVAFTGACITQDSPLKAVQMLWVNLIMDTFASLALATEPPTESLLKRRP 904 ++ ++ NV V+ F A + L VQ+LWVNL+ D + AL PP ++++ P Sbjct: 762 RYLISSNVGEVVCIFLTAILGLPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMEKLP 821 Query: 905 YGRNKPLISRTMMKNILGHAFYQLIVIFILV 935 + LIS G F++ + I + V Sbjct: 822 RSPREALIS--------GWLFFRYLAIGVYV 844 >gi|28373105 ATPase, Ca++ transporting, ubiquitous isoform e [Homo sapiens] Length = 1052 Score = 300 bits (767), Expect = 7e-81 Identities = 266/931 (28%), Positives = 431/931 (46%), Gaps = 175/931 (18%) Query: 69 NPADLEKRRQVFGHNVIPPKKPKTFLELVWEALQDVTLIILEIAAIISLVLSFYRPAGEE 128 +PA + R+ +G N +P ++ K+ ELV E +D+ + IL +AA++S VL+++ Sbjct: 25 SPAQVTGARERYGPNELPSEEGKSLWELVLEQFEDLLVRILLLAALVSFVLAWF------ 78 Query: 129 NELCGQVATTPEDENEAQAGWIEGAAILFSVIIVVLVTAFNDWSKEKQFRGLQCRIEQEQ 188 E+ E ++E I+ ++ +V + + + E L+ E E Sbjct: 79 -----------EEGEETTTAFVEPLVIMLILVANAIVGVWQERNAESAIEALK---EYEP 124 Query: 189 KFS-IIRNGQ--LIQLPVAEIVVGDIAQVKYGDLLPADGILIQ--GNDLKIDESSLTGES 243 + +IR+ + + ++ +IV GDI +V GD +PAD LI+ L++D+S LTGES Sbjct: 125 EMGKVIRSDRKGVQRIRARDIVPGDIVEVAVGDKVPADLRLIEIKSTTLRVDQSILTGES 184 Query: 244 DHVKK-----------SLDKDPMLLSGTHVMEGSGRMVVTAVGVNSQTGIILTLLGVNED 292 V K + DK ML SGT++ G AVGV TG+ T LG Sbjct: 185 VSVTKHTEAIPDPRAVNQDKKNMLFSGTNITSGK------AVGVAVATGLH-TELG---- 233 Query: 293 DEGEKKKKGKKQGVPENRNKAKTQDGVALEIQPLNSQEGIDNEEKDKKAVKVPKKEKSVL 352 K + + + E++ L Sbjct: 234 --------------------------------------------KIRSQMAAVEPERTPL 249 Query: 353 QGKLTRLAVQIGKAGLLMSALTVFILILYFVIDNFVINRRPWLPECTPIYIQYFVKFFII 412 Q KL Q+ A + + + V+++ + D P +++ V +F I Sbjct: 250 QRKLDEFGRQLSHA-ISVICVAVWVINIGHFAD----------PAHGGSWLRGAVYYFKI 298 Query: 413 GITVLVVAVPEGLPLAVTISLAYSVKKMMKDNNLVRHLDACETMGNATAICSDKTGTLTM 472 + + V A+PEGLP +T LA ++M + N +VR L + ET+G + ICSDKTGTLT Sbjct: 299 AVALAVAAIPEGLPAVITTCLALGTRRMARKNAIVRSLPSVETLGCTSVICSDKTGTLTT 358 Query: 473 NRMTVVQAYIGG--------IHYRQIPSPDVFLPK-------------VLDLIVNGISIN 511 N+M+V + ++ +H I S + P+ D +V +I Sbjct: 359 NQMSVCRMFVVAEADAGSCLLHEFTI-SGTTYTPEGEVRQGDQPVRCGQFDGLVELATIC 417 Query: 512 SAYTSKILPPEKEGGLPRQVGNKTECALLGFVTDLK---QDYQAVR--------NEVPEE 560 + L + G+ +VG TE AL V + D QA+ N V ++ Sbjct: 418 ALCNDSALDYNEAKGVYEKVGEATETALTCLVEKMNVFDTDLQALSRVERAGACNTVIKQ 477 Query: 561 KLYKVYT--FNSVRKSMSTVIR----NPNG-GFRMYSKGASEIILRKCNRILDRKGE-AV 612 + K +T F+ RKSMS +P G G +M+ KGA E ++ +C+ + R G Sbjct: 478 LMRKEFTLEFSRDRKSMSVYCTPTRPHPTGQGSKMFVKGAPESVIERCSSV--RVGSRTA 535 Query: 613 PFKNKDRDDMVRTVIE-PMACDGLRTICIAYRDFDDTEPSWDNEN-----EILTELTCIA 666 P R+ ++ + + D LR + +A RD + + ++ + T+LT + Sbjct: 536 PLTPTSREQILAKIRDWGSGSDTLRCLALATRDAPPRKEDMELDDCSKFVQYETDLTFVG 595 Query: 667 VVGIEDPVRPEVPDAIAKCKQAGITVRMVTGDNINTARAIATKCGILTPGDDFL--CLEG 724 VG+ DP RPEV I +C QAGI V M+TGDN TA AI + GI +D G Sbjct: 596 CVGMLDPPRPEVAACITRCYQAGIRVVMITGDNKGTAVAICRRLGIFGDTEDVAGKAYTG 655 Query: 725 KEFNRLIRNEKGEVEQEKLDKIWPKLRVLARSSPTDKHTLVKGIIDSTVGEHRQVVAVTG 784 +EF+ ++ E+ + R AR P K +V+ + ++ A+TG Sbjct: 656 REFD--------DLSPEQQRQACRTARCFARVEPAHKSRIVENL-----QSFNEITAMTG 702 Query: 785 DGTNDGPALKKADVGFAMGIAGTDVAKEASDIILTDDNFTSIVKAVMWGRNVYDSISKFL 844 DG ND PALKKA++G AMG +GT VAK A++++L+DDNF SIV AV GR +Y ++ +F+ Sbjct: 703 DGVNDAPALKKAEIGIAMG-SGTAVAKSAAEMVLSDDNFASIVAAVEEGRAIYSNMKQFI 761 Query: 845 QFQLTVNVVAVIVAFTGACITQDSPLKAVQMLWVNLIMDTFASLALATEPPTESLLKRRP 904 ++ ++ NV V+ F A + L VQ+LWVNL+ D + AL PP ++++ P Sbjct: 762 RYLISSNVGEVVCIFLTAILGLPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMEKLP 821 Query: 905 YGRNKPLISRTMMKNILGHAFYQLIVIFILV 935 + LIS G F++ + I + V Sbjct: 822 RSPREALIS--------GWLFFRYLAIGVYV 844 >gi|10835220 ATPase, Ca++ transporting, fast twitch 1 isoform b [Homo sapiens] Length = 994 Score = 295 bits (754), Expect = 2e-79 Identities = 265/904 (29%), Positives = 411/904 (45%), Gaps = 159/904 (17%) Query: 70 PADLEKRRQVFGHNVIPPKKPKTFLELVWEALQDVTLIILEIAAIISLVLSFYRPAGEEN 129 P +++ + +G N +P ++ KT ELV E +D+ + IL +AA IS VL+++ Sbjct: 26 PDQVKRNLEKYGLNELPAEEGKTLWELVIEQFEDLLVRILLLAACISFVLAWF------- 78 Query: 130 ELCGQVATTPEDENEAQAGWIEGAAILFSVIIVVLVTAFNDWSKEKQFRGLQCRIEQEQK 189 E+ E ++E IL +I +V + + + E L+ + K Sbjct: 79 ----------EEGEETITAFVEPFVILLILIANAIVGVWQERNAENAIEALKEYEPEMGK 128 Query: 190 FSIIRNGQLIQLPVAEIVVGDIAQVKYGDLLPADG--ILIQGNDLKIDESSLTGESDHVK 247 + ++ +IV GDI +V GD +PAD + I+ L++D+S LTGES V Sbjct: 129 VYRADRKSVQRIKARDIVPGDIVEVAVGDKVPADIRILAIKSTTLRVDQSILTGESVSVI 188 Query: 248 K-----------SLDKDPMLLSGTHVMEGSGRMVVTAVGVNSQTGIILTLLGVNEDDEGE 296 K + DK ML SGT++ G A+G+ + TG+ Sbjct: 189 KHTEPVPDPRAVNQDKKNMLFSGTNIAAGK------ALGIVATTGV-------------- 228 Query: 297 KKKKGKKQGVPENRNKAKTQDGVALEIQPLNSQEGIDNEEKDKKAVKVPKKEKSVLQGKL 356 G + G ++ A QD K+ LQ KL Sbjct: 229 ----GTEIGKIRDQMAATEQD-------------------------------KTPLQQKL 253 Query: 357 TRLAVQIGKAGLLMSALTVFILILYFVIDNFVINRRPWLPECTPIYIQYFVKFFIIGITV 416 Q+ K L+ I I +F N ++ W + +F I + + Sbjct: 254 DEFGEQLSKVISLICVAVWLINIGHF---NDPVHGGSWFRGA--------IYYFKIAVAL 302 Query: 417 LVVAVPEGLPLAVTISLAYSVKKMMKDNNLVRHLDACETMGNATAICSDKTGTLTMNRMT 476 V A+PEGLP +T LA ++M K N +VR L + ET+G + ICSDKTGTLT N+M+ Sbjct: 303 AVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQMS 362 Query: 477 VVQAYI-----------------GGIHYRQ---IPSPDVFLPKVLDLIVNGISINSAYTS 516 V + +I G + + + + P D +V +I + Sbjct: 363 VCKMFIIDKVDGDICLLNEFSITGSTYAPEGEVLKNDKPVRPGQYDGLVELATICALCND 422 Query: 517 KILPPEKEGGLPRQVGNKTECALLGFV-------TDLKQDYQAVR----NEVPEEKLYKV 565 L + G+ +VG TE AL V TD++ + R N V + + K Sbjct: 423 SSLDFNEAKGVYEKVGEATETALTTLVEKMNVFNTDVRSLSKVERANACNSVIRQLMKKE 482 Query: 566 YT--FNSVRKSMSTVIRNPNG-----GFRMYSKGASEIILRKCNRILDRKGEA-VPFKNK 617 +T F+ RKSMS G +M+ KGA E ++ +CN + R G VP Sbjct: 483 FTLEFSRDRKSMSVYCSPAKSSRAAVGNKMFVKGAPEGVIDRCNYV--RVGTTRVPLTGP 540 Query: 618 DRDDMVRTVIE-PMACDGLRTICIAYRDFDDT--EPSWDNENEIL---TELTCIAVVGIE 671 ++ ++ + E D LR + +A RD E D+ L T+LT + VVG+ Sbjct: 541 VKEKIMAVIKEWGTGRDTLRCLALATRDTPPKREEMVLDDSARFLEYETDLTFVGVVGML 600 Query: 672 DPVRPEVPDAIAKCKQAGITVRMVTGDNINTARAIATKCGILTPGDDFL--CLEGKEFNR 729 DP R EV +I C+ AGI V M+TGDN TA AI + GI ++ G+EF+ Sbjct: 601 DPPRKEVTGSIQLCRDAGIRVIMITGDNKGTAIAICRRIGIFGENEEVADRAYTGREFDD 660 Query: 730 LIRNEKGEVEQEKLDKIWPKLRVLARSSPTDKHTLVKGIIDSTVGEHRQVVAVTGDGTND 789 L E+ E + AR P+ K +V+ + + ++ A+TGDG ND Sbjct: 661 LPLAEQREACRRAC--------CFARVEPSHKSKIVEYL-----QSYDEITAMTGDGVND 707 Query: 790 GPALKKADVGFAMGIAGTDVAKEASDIILTDDNFTSIVKAVMWGRNVYDSISKFLQFQLT 849 PALKKA++G AMG +GT VAK AS+++L DDNF++IV AV GR +Y+++ +F+++ ++ Sbjct: 708 APALKKAEIGIAMG-SGTAVAKTASEMVLADDNFSTIVAAVEEGRAIYNNMKQFIRYLIS 766 Query: 850 VNVVAVIVAFTGACITQDSPLKAVQMLWVNLIMDTFASLALATEPPTESLLKRRPYGRNK 909 NV V+ F A + L VQ+LWVNL+ D + AL PP ++ R P + Sbjct: 767 SNVGEVVCIFLTAALGLPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMDRPPRSPKE 826 Query: 910 PLIS 913 PLIS Sbjct: 827 PLIS 830 >gi|27886529 ATPase, Ca++ transporting, fast twitch 1 isoform a [Homo sapiens] Length = 1001 Score = 295 bits (754), Expect = 2e-79 Identities = 265/904 (29%), Positives = 411/904 (45%), Gaps = 159/904 (17%) Query: 70 PADLEKRRQVFGHNVIPPKKPKTFLELVWEALQDVTLIILEIAAIISLVLSFYRPAGEEN 129 P +++ + +G N +P ++ KT ELV E +D+ + IL +AA IS VL+++ Sbjct: 26 PDQVKRNLEKYGLNELPAEEGKTLWELVIEQFEDLLVRILLLAACISFVLAWF------- 78 Query: 130 ELCGQVATTPEDENEAQAGWIEGAAILFSVIIVVLVTAFNDWSKEKQFRGLQCRIEQEQK 189 E+ E ++E IL +I +V + + + E L+ + K Sbjct: 79 ----------EEGEETITAFVEPFVILLILIANAIVGVWQERNAENAIEALKEYEPEMGK 128 Query: 190 FSIIRNGQLIQLPVAEIVVGDIAQVKYGDLLPADG--ILIQGNDLKIDESSLTGESDHVK 247 + ++ +IV GDI +V GD +PAD + I+ L++D+S LTGES V Sbjct: 129 VYRADRKSVQRIKARDIVPGDIVEVAVGDKVPADIRILAIKSTTLRVDQSILTGESVSVI 188 Query: 248 K-----------SLDKDPMLLSGTHVMEGSGRMVVTAVGVNSQTGIILTLLGVNEDDEGE 296 K + DK ML SGT++ G A+G+ + TG+ Sbjct: 189 KHTEPVPDPRAVNQDKKNMLFSGTNIAAGK------ALGIVATTGV-------------- 228 Query: 297 KKKKGKKQGVPENRNKAKTQDGVALEIQPLNSQEGIDNEEKDKKAVKVPKKEKSVLQGKL 356 G + G ++ A QD K+ LQ KL Sbjct: 229 ----GTEIGKIRDQMAATEQD-------------------------------KTPLQQKL 253 Query: 357 TRLAVQIGKAGLLMSALTVFILILYFVIDNFVINRRPWLPECTPIYIQYFVKFFIIGITV 416 Q+ K L+ I I +F N ++ W + +F I + + Sbjct: 254 DEFGEQLSKVISLICVAVWLINIGHF---NDPVHGGSWFRGA--------IYYFKIAVAL 302 Query: 417 LVVAVPEGLPLAVTISLAYSVKKMMKDNNLVRHLDACETMGNATAICSDKTGTLTMNRMT 476 V A+PEGLP +T LA ++M K N +VR L + ET+G + ICSDKTGTLT N+M+ Sbjct: 303 AVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQMS 362 Query: 477 VVQAYI-----------------GGIHYRQ---IPSPDVFLPKVLDLIVNGISINSAYTS 516 V + +I G + + + + P D +V +I + Sbjct: 363 VCKMFIIDKVDGDICLLNEFSITGSTYAPEGEVLKNDKPVRPGQYDGLVELATICALCND 422 Query: 517 KILPPEKEGGLPRQVGNKTECALLGFV-------TDLKQDYQAVR----NEVPEEKLYKV 565 L + G+ +VG TE AL V TD++ + R N V + + K Sbjct: 423 SSLDFNEAKGVYEKVGEATETALTTLVEKMNVFNTDVRSLSKVERANACNSVIRQLMKKE 482 Query: 566 YT--FNSVRKSMSTVIRNPNG-----GFRMYSKGASEIILRKCNRILDRKGEA-VPFKNK 617 +T F+ RKSMS G +M+ KGA E ++ +CN + R G VP Sbjct: 483 FTLEFSRDRKSMSVYCSPAKSSRAAVGNKMFVKGAPEGVIDRCNYV--RVGTTRVPLTGP 540 Query: 618 DRDDMVRTVIE-PMACDGLRTICIAYRDFDDT--EPSWDNENEIL---TELTCIAVVGIE 671 ++ ++ + E D LR + +A RD E D+ L T+LT + VVG+ Sbjct: 541 VKEKIMAVIKEWGTGRDTLRCLALATRDTPPKREEMVLDDSARFLEYETDLTFVGVVGML 600 Query: 672 DPVRPEVPDAIAKCKQAGITVRMVTGDNINTARAIATKCGILTPGDDFL--CLEGKEFNR 729 DP R EV +I C+ AGI V M+TGDN TA AI + GI ++ G+EF+ Sbjct: 601 DPPRKEVTGSIQLCRDAGIRVIMITGDNKGTAIAICRRIGIFGENEEVADRAYTGREFDD 660 Query: 730 LIRNEKGEVEQEKLDKIWPKLRVLARSSPTDKHTLVKGIIDSTVGEHRQVVAVTGDGTND 789 L E+ E + AR P+ K +V+ + + ++ A+TGDG ND Sbjct: 661 LPLAEQREACRRAC--------CFARVEPSHKSKIVEYL-----QSYDEITAMTGDGVND 707 Query: 790 GPALKKADVGFAMGIAGTDVAKEASDIILTDDNFTSIVKAVMWGRNVYDSISKFLQFQLT 849 PALKKA++G AMG +GT VAK AS+++L DDNF++IV AV GR +Y+++ +F+++ ++ Sbjct: 708 APALKKAEIGIAMG-SGTAVAKTASEMVLADDNFSTIVAAVEEGRAIYNNMKQFIRYLIS 766 Query: 850 VNVVAVIVAFTGACITQDSPLKAVQMLWVNLIMDTFASLALATEPPTESLLKRRPYGRNK 909 NV V+ F A + L VQ+LWVNL+ D + AL PP ++ R P + Sbjct: 767 SNVGEVVCIFLTAALGLPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMDRPPRSPKE 826 Query: 910 PLIS 913 PLIS Sbjct: 827 PLIS 830 >gi|24638454 ATPase, Ca++ transporting, slow twitch 2 isoform 1 [Homo sapiens] Length = 1042 Score = 294 bits (752), Expect = 4e-79 Identities = 303/1109 (27%), Positives = 483/1109 (43%), Gaps = 195/1109 (17%) Query: 45 NVHYGGVQNLCSRLKTSPVEGLSGNPADLEKRRQVFGHNVIPPKKPKTFLELVWEALQDV 104 N H V+ + + GLS ++K ++ +G N +P ++ KT LELV E +D+ Sbjct: 3 NAHTKTVEEVLGHFGVNESTGLSLE--QVKKLKERWGSNELPAEEGKTLLELVIEQFEDL 60 Query: 105 TLIILEIAAIISLVLSFYRPAGEENELCGQVATTPEDENEAQAGWIEGAAILFSVIIVVL 164 + IL +AA IS VL+++ E+ E ++E IL ++ + Sbjct: 61 LVRILLLAACISFVLAWF-----------------EEGEETITAFVEPFVILLILVANAI 103 Query: 165 VTAFNDWSKEKQFRGLQCRIEQEQKFSIIRNGQLIQ-LPVAEIVVGDIAQVKYGDLLPAD 223 V + + + E L+ E E ++ + +Q + +IV GDI ++ GD +PAD Sbjct: 104 VGVWQERNAENAIEALK-EYEPEMGKVYRQDRKSVQRIKAKDIVPGDIVEIAVGDKVPAD 162 Query: 224 GIL--IQGNDLKIDESSLTGESDHVKKSLDKDP-----------MLLSGTHVMEGSGRMV 270 L I+ L++D+S LTGES V K D P ML SGT++ G Sbjct: 163 IRLTSIKSTTLRVDQSILTGESVSVIKHTDPVPDPRAVNQDKKNMLFSGTNIAAGK---- 218 Query: 271 VTAVGVNSQTGIILTLLGVNEDDEGEKKKKGKKQGVPENRNKAKTQDGVALEIQPLNSQE 330 A+GV TG+ N++ Sbjct: 219 --AMGVVVATGV--------------------------------------------NTEI 232 Query: 331 GIDNEEKDKKAVKVPKKEKSVLQGKLTRLAVQIGKAGLLMSALTVFILILYFVIDNFVIN 390 G K + + ++E++ LQ KL Q+ K ++S + + + I+ N ++ Sbjct: 233 G-----KIRDEMVATEQERTPLQQKLDEFGEQLSK---VISLICIAVWIINIGHFNDPVH 284 Query: 391 RRPWLPECTPIYIQYFVKFFIIGITVLVVAVPEGLPLAVTISLAYSVKKMMKDNNLVRHL 450 W I+ + +F I + + V A+PEGLP +T LA ++M K N +VR L Sbjct: 285 GGSW--------IRGAIYYFKIAVALAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSL 336 Query: 451 DACETMGNATAICSDKTGTLTMNRMTVVQAYI------------------------GGIH 486 + ET+G + ICSDKTGTLT N+M+V + +I G +H Sbjct: 337 PSVETLGCTSVICSDKTGTLTTNQMSVCRMFILDRVEGDTCSLNEFTITGSTYAPIGEVH 396 Query: 487 YRQIPSPDVFLPKVLDLIVNGISINSAYTSKILPPEKEGGLPRQVGNKTECALLGFV--- 543 P D +V +I + L + G+ +VG TE AL V Sbjct: 397 KDDKPVNC----HQYDGLVELATICALCNDSALDYNEAKGVYEKVGEATETALTCLVEKM 452 Query: 544 ----TDLKQDYQAVR----NEVPEEKLYKVYT--FNSVRKSMSTVIRNPNGGFR-----M 588 T+LK + R N V ++ + K +T F+ RKSMS V PN R M Sbjct: 453 NVFDTELKGLSKIERANACNSVIKQLMKKEFTLEFSRDRKSMS-VYCTPNKPSRTSMSKM 511 Query: 589 YSKGASEIILRKCNRILDRKGEA-VPFKNKDRDDMVRTVIE-PMACDGLRTICIAYRDFD 646 + KGA E ++ +C I R G VP + + ++ + E D LR + +A D Sbjct: 512 FVKGAPEGVIDRCTHI--RVGSTKVPMTSGVKQKIMSVIREWGSGSDTLRCLALATHDNP 569 Query: 647 DTEPSW---DNENEIL--TELTCIAVVGIEDPVRPEVPDAIAKCKQAGITVRMVTGDNIN 701 D+ N I T LT + VG+ DP R EV ++ C+QAGI V M+TGDN Sbjct: 570 LRREEMHLEDSANFIKYETNLTFVGCVGMLDPPRIEVASSVKLCRQAGIRVIMITGDNKG 629 Query: 702 TARAIATKCGILTPGDDFL--CLEGKEFNRLIRNEKGEVEQEKLDKIWPKLRVLARSSPT 759 TA AI + GI +D G+EF+ L + + + R AR P+ Sbjct: 630 TAVAICRRIGIFGQDEDVTSKAFTGREFDELNPSAQRDA--------CLNARCFARVEPS 681 Query: 760 DKHTLVKGIIDSTVGEHRQVVAVTGDGTNDGPALKKADVGFAMGIAGTDVAKEASDIILT 819 K +V+ + ++ A+TGDG ND PALKKA++G AMG +GT VAK AS+++L Sbjct: 682 HKSKIVEFL-----QSFDEITAMTGDGVNDAPALKKAEIGIAMG-SGTAVAKTASEMVLA 735 Query: 820 DDNFTSIVKAVMWGRNVYDSISKFLQFQLTVNVVAVIVAFTGACITQDSPLKAVQMLWVN 879 DDNF++IV AV GR +Y+++ +F+++ ++ NV V+ F A + L VQ+LWVN Sbjct: 736 DDNFSTIVAAVEEGRAIYNNMKQFIRYLISSNVGEVVCIFLTAALGFPEALIPVQLLWVN 795 Query: 880 LIMDTFASLALATEPPTESLLKRRPYGRNKPLISRTMMKNILGHAFYQLIVI-------F 932 L+ D + AL PP ++ + P +PLIS + L Y F Sbjct: 796 LVTDGLPATALGFNPPDLDIMNKPPRNPKEPLISGWLFFRYLAIGCYVGAATVGAAAWWF 855 Query: 933 ILVFAGEK--FFDIDSGRKAPLHSPPSQ-----------HYTIVFNTFVLMQLFNEINSR 979 I G + F+ + + +P + T+ + V +++ N +NS Sbjct: 856 IAADGGPRVSFYQLSHFLQCKEDNPDFEGVDCAIFESPYPMTMALSVLVTIEMCNALNSL 915 Query: 980 KIHGEKNVFSGIYRNIIFCSVVLGTFICQIFIVEFGGKP--FSCTSLSLSQWLWCLFIGI 1037 + + + NI + + I+ P F T L+++QWL L I + Sbjct: 916 S-ENQSLLRMPPWENIWLVGSICLSMSLHFLILYVEPLPLIFQITPLNVTQWLMVLKISL 974 Query: 1038 GELLWGQFISAIPTRSLKFLKEAGHGTTK 1066 +L + + + L+ KE TK Sbjct: 975 PVILMDETLKFVARNYLEPGKECVQPATK 1003 >gi|4502285 ATPase, Ca++ transporting, slow twitch 2 isoform 2 [Homo sapiens] Length = 997 Score = 291 bits (745), Expect = 3e-78 Identities = 299/1098 (27%), Positives = 479/1098 (43%), Gaps = 195/1098 (17%) Query: 45 NVHYGGVQNLCSRLKTSPVEGLSGNPADLEKRRQVFGHNVIPPKKPKTFLELVWEALQDV 104 N H V+ + + GLS ++K ++ +G N +P ++ KT LELV E +D+ Sbjct: 3 NAHTKTVEEVLGHFGVNESTGLSLE--QVKKLKERWGSNELPAEEGKTLLELVIEQFEDL 60 Query: 105 TLIILEIAAIISLVLSFYRPAGEENELCGQVATTPEDENEAQAGWIEGAAILFSVIIVVL 164 + IL +AA IS VL+++ E+ E ++E IL ++ + Sbjct: 61 LVRILLLAACISFVLAWF-----------------EEGEETITAFVEPFVILLILVANAI 103 Query: 165 VTAFNDWSKEKQFRGLQCRIEQEQKFSIIRNGQLIQ-LPVAEIVVGDIAQVKYGDLLPAD 223 V + + + E L+ E E ++ + +Q + +IV GDI ++ GD +PAD Sbjct: 104 VGVWQERNAENAIEALK-EYEPEMGKVYRQDRKSVQRIKAKDIVPGDIVEIAVGDKVPAD 162 Query: 224 GIL--IQGNDLKIDESSLTGESDHVKKSLDKDP-----------MLLSGTHVMEGSGRMV 270 L I+ L++D+S LTGES V K D P ML SGT++ G Sbjct: 163 IRLTSIKSTTLRVDQSILTGESVSVIKHTDPVPDPRAVNQDKKNMLFSGTNIAAGK---- 218 Query: 271 VTAVGVNSQTGIILTLLGVNEDDEGEKKKKGKKQGVPENRNKAKTQDGVALEIQPLNSQE 330 A+GV TG+ N++ Sbjct: 219 --AMGVVVATGV--------------------------------------------NTEI 232 Query: 331 GIDNEEKDKKAVKVPKKEKSVLQGKLTRLAVQIGKAGLLMSALTVFILILYFVIDNFVIN 390 G K + + ++E++ LQ KL Q+ K ++S + + + I+ N ++ Sbjct: 233 G-----KIRDEMVATEQERTPLQQKLDEFGEQLSK---VISLICIAVWIINIGHFNDPVH 284 Query: 391 RRPWLPECTPIYIQYFVKFFIIGITVLVVAVPEGLPLAVTISLAYSVKKMMKDNNLVRHL 450 W I+ + +F I + + V A+PEGLP +T LA ++M K N +VR L Sbjct: 285 GGSW--------IRGAIYYFKIAVALAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSL 336 Query: 451 DACETMGNATAICSDKTGTLTMNRMTVVQAYI------------------------GGIH 486 + ET+G + ICSDKTGTLT N+M+V + +I G +H Sbjct: 337 PSVETLGCTSVICSDKTGTLTTNQMSVCRMFILDRVEGDTCSLNEFTITGSTYAPIGEVH 396 Query: 487 YRQIPSPDVFLPKVLDLIVNGISINSAYTSKILPPEKEGGLPRQVGNKTECALLGFV--- 543 P D +V +I + L + G+ +VG TE AL V Sbjct: 397 KDDKPVNC----HQYDGLVELATICALCNDSALDYNEAKGVYEKVGEATETALTCLVEKM 452 Query: 544 ----TDLKQDYQAVR----NEVPEEKLYKVYT--FNSVRKSMSTVIRNPNGGFR-----M 588 T+LK + R N V ++ + K +T F+ RKSMS V PN R M Sbjct: 453 NVFDTELKGLSKIERANACNSVIKQLMKKEFTLEFSRDRKSMS-VYCTPNKPSRTSMSKM 511 Query: 589 YSKGASEIILRKCNRILDRKGEA-VPFKNKDRDDMVRTVIE-PMACDGLRTICIAYRDFD 646 + KGA E ++ +C I R G VP + + ++ + E D LR + +A D Sbjct: 512 FVKGAPEGVIDRCTHI--RVGSTKVPMTSGVKQKIMSVIREWGSGSDTLRCLALATHDNP 569 Query: 647 DTEPSW---DNENEIL--TELTCIAVVGIEDPVRPEVPDAIAKCKQAGITVRMVTGDNIN 701 D+ N I T LT + VG+ DP R EV ++ C+QAGI V M+TGDN Sbjct: 570 LRREEMHLEDSANFIKYETNLTFVGCVGMLDPPRIEVASSVKLCRQAGIRVIMITGDNKG 629 Query: 702 TARAIATKCGILTPGDDFL--CLEGKEFNRLIRNEKGEVEQEKLDKIWPKLRVLARSSPT 759 TA AI + GI +D G+EF+ L + + + R AR P+ Sbjct: 630 TAVAICRRIGIFGQDEDVTSKAFTGREFDELNPSAQRDA--------CLNARCFARVEPS 681 Query: 760 DKHTLVKGIIDSTVGEHRQVVAVTGDGTNDGPALKKADVGFAMGIAGTDVAKEASDIILT 819 K +V+ + ++ A+TGDG ND PALKKA++G AMG +GT VAK AS+++L Sbjct: 682 HKSKIVEFL-----QSFDEITAMTGDGVNDAPALKKAEIGIAMG-SGTAVAKTASEMVLA 735 Query: 820 DDNFTSIVKAVMWGRNVYDSISKFLQFQLTVNVVAVIVAFTGACITQDSPLKAVQMLWVN 879 DDNF++IV AV GR +Y+++ +F+++ ++ NV V+ F A + L VQ+LWVN Sbjct: 736 DDNFSTIVAAVEEGRAIYNNMKQFIRYLISSNVGEVVCIFLTAALGFPEALIPVQLLWVN 795 Query: 880 LIMDTFASLALATEPPTESLLKRRPYGRNKPLISRTMMKNILGHAFYQLIVI-------F 932 L+ D + AL PP ++ + P +PLIS + L Y F Sbjct: 796 LVTDGLPATALGFNPPDLDIMNKPPRNPKEPLISGWLFFRYLAIGCYVGAATVGAAAWWF 855 Query: 933 ILVFAGEK--FFDIDSGRKAPLHSPPSQ-----------HYTIVFNTFVLMQLFNEINSR 979 I G + F+ + + +P + T+ + V +++ N +NS Sbjct: 856 IAADGGPRVSFYQLSHFLQCKEDNPDFEGVDCAIFESPYPMTMALSVLVTIEMCNALNSL 915 Query: 980 KIHGEKNVFSGIYRNIIFCSVVLGTFICQIFIVEFGGKP--FSCTSLSLSQWLWCLFIGI 1037 + + + NI + + I+ P F T L+++QWL L I + Sbjct: 916 S-ENQSLLRMPPWENIWLVGSICLSMSLHFLILYVEPLPLIFQITPLNVTQWLMVLKISL 974 Query: 1038 GELLWGQFISAIPTRSLK 1055 +L + + + L+ Sbjct: 975 PVILMDETLKFVARNYLE 992 >gi|48762691 calcium-transporting ATPase 2C1 isoform 1b [Homo sapiens] Length = 939 Score = 290 bits (743), Expect = 4e-78 Identities = 253/910 (27%), Positives = 420/910 (46%), Gaps = 156/910 (17%) Query: 151 EGAAILFSVIIVVLVTAFNDWSKEKQFRGLQCRIEQEQKFSIIRNGQLIQLPVAEIVVGD 210 + +I +++IVV V ++ EK L + E +R G+L ++V GD Sbjct: 102 DAVSITVAILIVVTVAFVQEYRSEKSLEELSKLVPPE--CHCVREGKLEHTLARDLVPGD 159 Query: 211 IAQVKYGDLLPADGILIQGNDLKIDESSLTGESDHVKKSLDKDPMLLSGTHVMEGSGRMV 270 + GD +PAD L + DL IDESSLTGE+ K P +G + + R Sbjct: 160 TVCLSVGDRVPADLRLFEAVDLSIDESSLTGETTPCSKVTAPQPAATNG----DLASRSN 215 Query: 271 VTAVGVNSQTGIILTLLGVNEDDEGEKKKKGKKQGVPENRNKAKTQDGVALEIQPLNSQE 330 + +G + G K KG G EN ++ G ++ Sbjct: 216 IAFMGTLVRCG----------------KAKGVVIGTGEN-----SEFGEVFKMM------ 248 Query: 331 GIDNEEKDKKAVKVPKKEKSVLQGKLTRLAVQIGKAGLLMSALTVFILILYFVIDNFVIN 390 + ++A K P ++ L GK G G++M Sbjct: 249 ------QAEEAPKTPLQKSMDLLGKQLSF-YSFGIIGIIMLV------------------ 283 Query: 391 RRPWLPECTPIYIQYFVKFFIIGITVLVVAVPEGLPLAVTISLAYSVKKMMKDNNLVRHL 450 WL + ++ F I +++ V A+PEGLP+ VT++LA V +M+K +V+ L Sbjct: 284 --GWLLG------KDILEMFTISVSLAVAAIPEGLPIVVTVTLALGVMRMVKKRAIVKKL 335 Query: 451 DACETMGNATAICSDKTGTLTMNRMTV--------VQAYIGGIHYRQIPSPDVFLPKVLD 502 ET+G ICSDKTGTLT N MTV + A + G+ Y Q + Sbjct: 336 PIVETLGCCNVICSDKTGTLTKNEMTVTHIFTSDGLHAEVTGVGYNQFG----------E 385 Query: 503 LIVNGISINSAYTSKILPPEKEGGLPRQ--------VGNKTECALLGF-----VTDLKQD 549 +IV+G ++ Y + + G + +G TE AL+ + L+QD Sbjct: 386 VIVDGDVVHGFYNPAVSRIVEAGCVCNDAVIRNNTLMGKPTEGALIALAMKMGLDGLQQD 445 Query: 550 YQAVRNEVPEEKLYKVYTFNSVRKSMSTVIRNPNGGFR---MYSKGASEIILRKCNRILD 606 Y +R Y F+S +K M+ + R + KGA E +++ C Sbjct: 446 Y--IRKAE--------YPFSSEQKWMAVKCVHRTQQDRPEICFMKGAYEQVIKYCTTY-Q 494 Query: 607 RKGEAVPFKNKDRDDMVRTVIEPMACDGLRTICIAYRDFDDTEPSWDNENEILTELTCIA 666 KG+ + + RD + + M GLR + +A L +LT + Sbjct: 495 SKGQTLTLTQQQRD-VYQQEKARMGSAGLRVLALA-------------SGPELGQLTFLG 540 Query: 667 VVGIEDPVRPEVPDAIAKCKQAGITVRMVTGDNINTARAIATKCGILTPGDDFLCLEGKE 726 +VGI DP R V +A+ +G++++M+TGD+ TA AIA++ G+ + + G+E Sbjct: 541 LVGIIDPPRTGVKEAVTTLIASGVSIKMITGDSQETAVAIASRLGLYSKTSQ--SVSGEE 598 Query: 727 FNRLIRNEKGEVEQEKLDKIWPKLRVLARSSPTDKHTLVKGIIDSTVGEHRQVVAVTGDG 786 + + + ++L +I PK+ V R+SP K ++K + ++ VVA+TGDG Sbjct: 599 IDAM--------DVQQLSQIVPKVAVFYRASPRHKMKIIKSL-----QKNGSVVAMTGDG 645 Query: 787 TNDGPALKKADVGFAMGIAGTDVAKEASDIILTDDNFTSIVKAVMWGRNVYDSISKFLQF 846 ND ALK AD+G AMG GTDV KEA+D+IL DD+F +I+ A+ G+ +Y++I F++F Sbjct: 646 VNDAVALKAADIGVAMGQTGTDVCKEAADMILVDDDFQTIMSAIEEGKGIYNNIKNFVRF 705 Query: 847 QLTVNVVAVIVAFTGACITQDSPLKAVQMLWVNLIMDTFASLALATEPPTESLLKRRPYG 906 QL+ ++ A+ + + +PL A+Q+LW+N+IMD + +L EP + ++++ P Sbjct: 706 QLSTSIAALTLISLATLMNFPNPLNAMQILWINIIMDGPPAQSLGVEPVDKDVIRKPPRN 765 Query: 907 RNKPLISRTMMKNILGHAFYQLIVIFILVFAGEKFFDIDSGRKAPLHSPPSQHYTIVFNT 966 ++++ ++ IL V I++ G F R+ + + T+ F Sbjct: 766 WKDSILTKNLILKIL--------VSSIIIVCGTLFV---FWRELRDNVITPRDTTMTFTC 814 Query: 967 FVLMQLFNEINSRKIHGEKNVFS-GIYRNIIFCSVVLGTFICQIFIVEFG--GKPFSCTS 1023 FV +FN ++SR K+VF G+ N +FC VLG+ + Q+ ++ F K F S Sbjct: 815 FVFFDMFNALSSRS--QTKSVFEIGLCSNRMFCYAVLGSIMGQLLVIYFPPLQKVFQTES 872 Query: 1024 LSLSQWLWCL 1033 LS+ L+ L Sbjct: 873 LSILDLLFLL 882 >gi|48762689 calcium-transporting ATPase 2C1 isoform 1d [Homo sapiens] Length = 949 Score = 290 bits (743), Expect = 4e-78 Identities = 253/910 (27%), Positives = 420/910 (46%), Gaps = 156/910 (17%) Query: 151 EGAAILFSVIIVVLVTAFNDWSKEKQFRGLQCRIEQEQKFSIIRNGQLIQLPVAEIVVGD 210 + +I +++IVV V ++ EK L + E +R G+L ++V GD Sbjct: 102 DAVSITVAILIVVTVAFVQEYRSEKSLEELSKLVPPE--CHCVREGKLEHTLARDLVPGD 159 Query: 211 IAQVKYGDLLPADGILIQGNDLKIDESSLTGESDHVKKSLDKDPMLLSGTHVMEGSGRMV 270 + GD +PAD L + DL IDESSLTGE+ K P +G + + R Sbjct: 160 TVCLSVGDRVPADLRLFEAVDLSIDESSLTGETTPCSKVTAPQPAATNG----DLASRSN 215 Query: 271 VTAVGVNSQTGIILTLLGVNEDDEGEKKKKGKKQGVPENRNKAKTQDGVALEIQPLNSQE 330 + +G + G K KG G EN ++ G ++ Sbjct: 216 IAFMGTLVRCG----------------KAKGVVIGTGEN-----SEFGEVFKMM------ 248 Query: 331 GIDNEEKDKKAVKVPKKEKSVLQGKLTRLAVQIGKAGLLMSALTVFILILYFVIDNFVIN 390 + ++A K P ++ L GK G G++M Sbjct: 249 ------QAEEAPKTPLQKSMDLLGKQLSF-YSFGIIGIIMLV------------------ 283 Query: 391 RRPWLPECTPIYIQYFVKFFIIGITVLVVAVPEGLPLAVTISLAYSVKKMMKDNNLVRHL 450 WL + ++ F I +++ V A+PEGLP+ VT++LA V +M+K +V+ L Sbjct: 284 --GWLLG------KDILEMFTISVSLAVAAIPEGLPIVVTVTLALGVMRMVKKRAIVKKL 335 Query: 451 DACETMGNATAICSDKTGTLTMNRMTV--------VQAYIGGIHYRQIPSPDVFLPKVLD 502 ET+G ICSDKTGTLT N MTV + A + G+ Y Q + Sbjct: 336 PIVETLGCCNVICSDKTGTLTKNEMTVTHIFTSDGLHAEVTGVGYNQFG----------E 385 Query: 503 LIVNGISINSAYTSKILPPEKEGGLPRQ--------VGNKTECALLGF-----VTDLKQD 549 +IV+G ++ Y + + G + +G TE AL+ + L+QD Sbjct: 386 VIVDGDVVHGFYNPAVSRIVEAGCVCNDAVIRNNTLMGKPTEGALIALAMKMGLDGLQQD 445 Query: 550 YQAVRNEVPEEKLYKVYTFNSVRKSMSTVIRNPNGGFR---MYSKGASEIILRKCNRILD 606 Y +R Y F+S +K M+ + R + KGA E +++ C Sbjct: 446 Y--IRKAE--------YPFSSEQKWMAVKCVHRTQQDRPEICFMKGAYEQVIKYCTTY-Q 494 Query: 607 RKGEAVPFKNKDRDDMVRTVIEPMACDGLRTICIAYRDFDDTEPSWDNENEILTELTCIA 666 KG+ + + RD + + M GLR + +A L +LT + Sbjct: 495 SKGQTLTLTQQQRD-VYQQEKARMGSAGLRVLALA-------------SGPELGQLTFLG 540 Query: 667 VVGIEDPVRPEVPDAIAKCKQAGITVRMVTGDNINTARAIATKCGILTPGDDFLCLEGKE 726 +VGI DP R V +A+ +G++++M+TGD+ TA AIA++ G+ + + G+E Sbjct: 541 LVGIIDPPRTGVKEAVTTLIASGVSIKMITGDSQETAVAIASRLGLYSKTSQ--SVSGEE 598 Query: 727 FNRLIRNEKGEVEQEKLDKIWPKLRVLARSSPTDKHTLVKGIIDSTVGEHRQVVAVTGDG 786 + + + ++L +I PK+ V R+SP K ++K + ++ VVA+TGDG Sbjct: 599 IDAM--------DVQQLSQIVPKVAVFYRASPRHKMKIIKSL-----QKNGSVVAMTGDG 645 Query: 787 TNDGPALKKADVGFAMGIAGTDVAKEASDIILTDDNFTSIVKAVMWGRNVYDSISKFLQF 846 ND ALK AD+G AMG GTDV KEA+D+IL DD+F +I+ A+ G+ +Y++I F++F Sbjct: 646 VNDAVALKAADIGVAMGQTGTDVCKEAADMILVDDDFQTIMSAIEEGKGIYNNIKNFVRF 705 Query: 847 QLTVNVVAVIVAFTGACITQDSPLKAVQMLWVNLIMDTFASLALATEPPTESLLKRRPYG 906 QL+ ++ A+ + + +PL A+Q+LW+N+IMD + +L EP + ++++ P Sbjct: 706 QLSTSIAALTLISLATLMNFPNPLNAMQILWINIIMDGPPAQSLGVEPVDKDVIRKPPRN 765 Query: 907 RNKPLISRTMMKNILGHAFYQLIVIFILVFAGEKFFDIDSGRKAPLHSPPSQHYTIVFNT 966 ++++ ++ IL V I++ G F R+ + + T+ F Sbjct: 766 WKDSILTKNLILKIL--------VSSIIIVCGTLFV---FWRELRDNVITPRDTTMTFTC 814 Query: 967 FVLMQLFNEINSRKIHGEKNVFS-GIYRNIIFCSVVLGTFICQIFIVEFG--GKPFSCTS 1023 FV +FN ++SR K+VF G+ N +FC VLG+ + Q+ ++ F K F S Sbjct: 815 FVFFDMFNALSSRS--QTKSVFEIGLCSNRMFCYAVLGSIMGQLLVIYFPPLQKVFQTES 872 Query: 1024 LSLSQWLWCL 1033 LS+ L+ L Sbjct: 873 LSILDLLFLL 882 >gi|48762685 calcium-transporting ATPase 2C1 isoform 1a [Homo sapiens] Length = 919 Score = 290 bits (743), Expect = 4e-78 Identities = 253/910 (27%), Positives = 420/910 (46%), Gaps = 156/910 (17%) Query: 151 EGAAILFSVIIVVLVTAFNDWSKEKQFRGLQCRIEQEQKFSIIRNGQLIQLPVAEIVVGD 210 + +I +++IVV V ++ EK L + E +R G+L ++V GD Sbjct: 102 DAVSITVAILIVVTVAFVQEYRSEKSLEELSKLVPPE--CHCVREGKLEHTLARDLVPGD 159 Query: 211 IAQVKYGDLLPADGILIQGNDLKIDESSLTGESDHVKKSLDKDPMLLSGTHVMEGSGRMV 270 + GD +PAD L + DL IDESSLTGE+ K P +G + + R Sbjct: 160 TVCLSVGDRVPADLRLFEAVDLSIDESSLTGETTPCSKVTAPQPAATNG----DLASRSN 215 Query: 271 VTAVGVNSQTGIILTLLGVNEDDEGEKKKKGKKQGVPENRNKAKTQDGVALEIQPLNSQE 330 + +G + G K KG G EN ++ G ++ Sbjct: 216 IAFMGTLVRCG----------------KAKGVVIGTGEN-----SEFGEVFKMM------ 248 Query: 331 GIDNEEKDKKAVKVPKKEKSVLQGKLTRLAVQIGKAGLLMSALTVFILILYFVIDNFVIN 390 + ++A K P ++ L GK G G++M Sbjct: 249 ------QAEEAPKTPLQKSMDLLGKQLSF-YSFGIIGIIMLV------------------ 283 Query: 391 RRPWLPECTPIYIQYFVKFFIIGITVLVVAVPEGLPLAVTISLAYSVKKMMKDNNLVRHL 450 WL + ++ F I +++ V A+PEGLP+ VT++LA V +M+K +V+ L Sbjct: 284 --GWLLG------KDILEMFTISVSLAVAAIPEGLPIVVTVTLALGVMRMVKKRAIVKKL 335 Query: 451 DACETMGNATAICSDKTGTLTMNRMTV--------VQAYIGGIHYRQIPSPDVFLPKVLD 502 ET+G ICSDKTGTLT N MTV + A + G+ Y Q + Sbjct: 336 PIVETLGCCNVICSDKTGTLTKNEMTVTHIFTSDGLHAEVTGVGYNQFG----------E 385 Query: 503 LIVNGISINSAYTSKILPPEKEGGLPRQ--------VGNKTECALLGF-----VTDLKQD 549 +IV+G ++ Y + + G + +G TE AL+ + L+QD Sbjct: 386 VIVDGDVVHGFYNPAVSRIVEAGCVCNDAVIRNNTLMGKPTEGALIALAMKMGLDGLQQD 445 Query: 550 YQAVRNEVPEEKLYKVYTFNSVRKSMSTVIRNPNGGFR---MYSKGASEIILRKCNRILD 606 Y +R Y F+S +K M+ + R + KGA E +++ C Sbjct: 446 Y--IRKAE--------YPFSSEQKWMAVKCVHRTQQDRPEICFMKGAYEQVIKYCTTY-Q 494 Query: 607 RKGEAVPFKNKDRDDMVRTVIEPMACDGLRTICIAYRDFDDTEPSWDNENEILTELTCIA 666 KG+ + + RD + + M GLR + +A L +LT + Sbjct: 495 SKGQTLTLTQQQRD-VYQQEKARMGSAGLRVLALA-------------SGPELGQLTFLG 540 Query: 667 VVGIEDPVRPEVPDAIAKCKQAGITVRMVTGDNINTARAIATKCGILTPGDDFLCLEGKE 726 +VGI DP R V +A+ +G++++M+TGD+ TA AIA++ G+ + + G+E Sbjct: 541 LVGIIDPPRTGVKEAVTTLIASGVSIKMITGDSQETAVAIASRLGLYSKTSQ--SVSGEE 598 Query: 727 FNRLIRNEKGEVEQEKLDKIWPKLRVLARSSPTDKHTLVKGIIDSTVGEHRQVVAVTGDG 786 + + + ++L +I PK+ V R+SP K ++K + ++ VVA+TGDG Sbjct: 599 IDAM--------DVQQLSQIVPKVAVFYRASPRHKMKIIKSL-----QKNGSVVAMTGDG 645 Query: 787 TNDGPALKKADVGFAMGIAGTDVAKEASDIILTDDNFTSIVKAVMWGRNVYDSISKFLQF 846 ND ALK AD+G AMG GTDV KEA+D+IL DD+F +I+ A+ G+ +Y++I F++F Sbjct: 646 VNDAVALKAADIGVAMGQTGTDVCKEAADMILVDDDFQTIMSAIEEGKGIYNNIKNFVRF 705 Query: 847 QLTVNVVAVIVAFTGACITQDSPLKAVQMLWVNLIMDTFASLALATEPPTESLLKRRPYG 906 QL+ ++ A+ + + +PL A+Q+LW+N+IMD + +L EP + ++++ P Sbjct: 706 QLSTSIAALTLISLATLMNFPNPLNAMQILWINIIMDGPPAQSLGVEPVDKDVIRKPPRN 765 Query: 907 RNKPLISRTMMKNILGHAFYQLIVIFILVFAGEKFFDIDSGRKAPLHSPPSQHYTIVFNT 966 ++++ ++ IL V I++ G F R+ + + T+ F Sbjct: 766 WKDSILTKNLILKIL--------VSSIIIVCGTLFV---FWRELRDNVITPRDTTMTFTC 814 Query: 967 FVLMQLFNEINSRKIHGEKNVFS-GIYRNIIFCSVVLGTFICQIFIVEFG--GKPFSCTS 1023 FV +FN ++SR K+VF G+ N +FC VLG+ + Q+ ++ F K F S Sbjct: 815 FVFFDMFNALSSRS--QTKSVFEIGLCSNRMFCYAVLGSIMGQLLVIYFPPLQKVFQTES 872 Query: 1024 LSLSQWLWCL 1033 LS+ L+ L Sbjct: 873 LSILDLLFLL 882 >gi|48762687 calcium-transporting ATPase 2C1 isoform 1c [Homo sapiens] Length = 888 Score = 289 bits (739), Expect = 1e-77 Identities = 251/903 (27%), Positives = 417/903 (46%), Gaps = 156/903 (17%) Query: 151 EGAAILFSVIIVVLVTAFNDWSKEKQFRGLQCRIEQEQKFSIIRNGQLIQLPVAEIVVGD 210 + +I +++IVV V ++ EK L + E +R G+L ++V GD Sbjct: 102 DAVSITVAILIVVTVAFVQEYRSEKSLEELSKLVPPE--CHCVREGKLEHTLARDLVPGD 159 Query: 211 IAQVKYGDLLPADGILIQGNDLKIDESSLTGESDHVKKSLDKDPMLLSGTHVMEGSGRMV 270 + GD +PAD L + DL IDESSLTGE+ K P +G + + R Sbjct: 160 TVCLSVGDRVPADLRLFEAVDLSIDESSLTGETTPCSKVTAPQPAATNG----DLASRSN 215 Query: 271 VTAVGVNSQTGIILTLLGVNEDDEGEKKKKGKKQGVPENRNKAKTQDGVALEIQPLNSQE 330 + +G + G K KG G EN ++ G ++ Sbjct: 216 IAFMGTLVRCG----------------KAKGVVIGTGEN-----SEFGEVFKMM------ 248 Query: 331 GIDNEEKDKKAVKVPKKEKSVLQGKLTRLAVQIGKAGLLMSALTVFILILYFVIDNFVIN 390 + ++A K P ++ L GK G G++M Sbjct: 249 ------QAEEAPKTPLQKSMDLLGKQLSF-YSFGIIGIIMLV------------------ 283 Query: 391 RRPWLPECTPIYIQYFVKFFIIGITVLVVAVPEGLPLAVTISLAYSVKKMMKDNNLVRHL 450 WL + ++ F I +++ V A+PEGLP+ VT++LA V +M+K +V+ L Sbjct: 284 --GWLLG------KDILEMFTISVSLAVAAIPEGLPIVVTVTLALGVMRMVKKRAIVKKL 335 Query: 451 DACETMGNATAICSDKTGTLTMNRMTV--------VQAYIGGIHYRQIPSPDVFLPKVLD 502 ET+G ICSDKTGTLT N MTV + A + G+ Y Q + Sbjct: 336 PIVETLGCCNVICSDKTGTLTKNEMTVTHIFTSDGLHAEVTGVGYNQFG----------E 385 Query: 503 LIVNGISINSAYTSKILPPEKEGGLPRQ--------VGNKTECALLGF-----VTDLKQD 549 +IV+G ++ Y + + G + +G TE AL+ + L+QD Sbjct: 386 VIVDGDVVHGFYNPAVSRIVEAGCVCNDAVIRNNTLMGKPTEGALIALAMKMGLDGLQQD 445 Query: 550 YQAVRNEVPEEKLYKVYTFNSVRKSMSTVIRNPNGGFR---MYSKGASEIILRKCNRILD 606 Y +R Y F+S +K M+ + R + KGA E +++ C Sbjct: 446 Y--IRKAE--------YPFSSEQKWMAVKCVHRTQQDRPEICFMKGAYEQVIKYCTTY-Q 494 Query: 607 RKGEAVPFKNKDRDDMVRTVIEPMACDGLRTICIAYRDFDDTEPSWDNENEILTELTCIA 666 KG+ + + RD + + M GLR + +A L +LT + Sbjct: 495 SKGQTLTLTQQQRD-VYQQEKARMGSAGLRVLALA-------------SGPELGQLTFLG 540 Query: 667 VVGIEDPVRPEVPDAIAKCKQAGITVRMVTGDNINTARAIATKCGILTPGDDFLCLEGKE 726 +VGI DP R V +A+ +G++++M+TGD+ TA AIA++ G+ + + G+E Sbjct: 541 LVGIIDPPRTGVKEAVTTLIASGVSIKMITGDSQETAVAIASRLGLYSKTSQ--SVSGEE 598 Query: 727 FNRLIRNEKGEVEQEKLDKIWPKLRVLARSSPTDKHTLVKGIIDSTVGEHRQVVAVTGDG 786 + + + ++L +I PK+ V R+SP K ++K + ++ VVA+TGDG Sbjct: 599 IDAM--------DVQQLSQIVPKVAVFYRASPRHKMKIIKSL-----QKNGSVVAMTGDG 645 Query: 787 TNDGPALKKADVGFAMGIAGTDVAKEASDIILTDDNFTSIVKAVMWGRNVYDSISKFLQF 846 ND ALK AD+G AMG GTDV KEA+D+IL DD+F +I+ A+ G+ +Y++I F++F Sbjct: 646 VNDAVALKAADIGVAMGQTGTDVCKEAADMILVDDDFQTIMSAIEEGKGIYNNIKNFVRF 705 Query: 847 QLTVNVVAVIVAFTGACITQDSPLKAVQMLWVNLIMDTFASLALATEPPTESLLKRRPYG 906 QL+ ++ A+ + + +PL A+Q+LW+N+IMD + +L EP + ++++ P Sbjct: 706 QLSTSIAALTLISLATLMNFPNPLNAMQILWINIIMDGPPAQSLGVEPVDKDVIRKPPRN 765 Query: 907 RNKPLISRTMMKNILGHAFYQLIVIFILVFAGEKFFDIDSGRKAPLHSPPSQHYTIVFNT 966 ++++ ++ IL V I++ G F R+ + + T+ F Sbjct: 766 WKDSILTKNLILKIL--------VSSIIIVCGTLFV---FWRELRDNVITPRDTTMTFTC 814 Query: 967 FVLMQLFNEINSRKIHGEKNVFS-GIYRNIIFCSVVLGTFICQIFIVEFG--GKPFSCTS 1023 FV +FN ++SR K+VF G+ N +FC VLG+ + Q+ ++ F K F S Sbjct: 815 FVFFDMFNALSSRS--QTKSVFEIGLCSNRMFCYAVLGSIMGQLLVIYFPPLQKVFQTES 872 Query: 1024 LSL 1026 LS+ Sbjct: 873 LSI 875 >gi|209413709 ATPase, Ca++ transporting, slow twitch 2 isoform 3 [Homo sapiens] Length = 1015 Score = 270 bits (689), Expect = 8e-72 Identities = 288/1095 (26%), Positives = 469/1095 (42%), Gaps = 194/1095 (17%) Query: 45 NVHYGGVQNLCSRLKTSPVEGLSGNPADLEKRRQVFGHNVIPPKKPKTFLELVWEALQDV 104 N H V+ + + GLS ++K ++ +G N +P ++ KT LELV E +D+ Sbjct: 3 NAHTKTVEEVLGHFGVNESTGLSLE--QVKKLKERWGSNELPAEEGKTLLELVIEQFEDL 60 Query: 105 TLIILEIAAIISLVLSFYRPAGEENELCGQVATTPEDENEAQAGWIEGAAILFSVIIVVL 164 + IL +AA IS VL+++ E+ E ++E IL ++ + Sbjct: 61 LVRILLLAACISFVLAWF-----------------EEGEETITAFVEPFVILLILVANAI 103 Query: 165 VTAFNDWSKEKQFRGLQCRIEQEQKFSIIRNGQLIQLPVAEIVVGDIAQVKYGDLLPADG 224 V + + + E L+ E E ++ + +Q ++K D++P D Sbjct: 104 VGVWQERNAENAIEALK-EYEPEMGKVYRQDRKSVQ------------RIKAKDIVPGDI 150 Query: 225 ILIQGNDLKIDESSLTGESDHVKKSLDKDPMLLSGTHVMEGSGRMVVTAVGVNSQTGIIL 284 + I G + + + + D + DK ML SGT++ G A+GV TG+ Sbjct: 151 VEIAGESVSVIKHT-DPVPDPRAVNQDKKNMLFSGTNIAAGK------AMGVVVATGV-- 201 Query: 285 TLLGVNEDDEGEKKKKGKKQGVPENRNKAKTQDGVALEIQPLNSQEGIDNEEKDKKAVKV 344 N++ G K + + Sbjct: 202 ------------------------------------------NTEIG-----KIRDEMVA 214 Query: 345 PKKEKSVLQGKLTRLAVQIGKAGLLMSALTVFILILYFVIDNFVINRRPWLPECTPIYIQ 404 ++E++ LQ KL Q+ K ++S + + + I+ N ++ W I+ Sbjct: 215 TEQERTPLQQKLDEFGEQLSK---VISLICIAVWIINIGHFNDPVHGGSW--------IR 263 Query: 405 YFVKFFIIGITVLVVAVPEGLPLAVTISLAYSVKKMMKDNNLVRHLDACETMGNATAICS 464 + +F I + + V A+PEGLP +T LA ++M K N +VR L + ET+G + ICS Sbjct: 264 GAIYYFKIAVALAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICS 323 Query: 465 DKTGTLTMNRMTVVQAYI------------------------GGIHYRQIPSPDVFLPKV 500 DKTGTLT N+M+V + +I G +H P Sbjct: 324 DKTGTLTTNQMSVCRMFILDRVEGDTCSLNEFTITGSTYAPIGEVHKDDKPVNC----HQ 379 Query: 501 LDLIVNGISINSAYTSKILPPEKEGGLPRQVGNKTECALLGFV-------TDLKQDYQAV 553 D +V +I + L + G+ +VG TE AL V T+LK + Sbjct: 380 YDGLVELATICALCNDSALDYNEAKGVYEKVGEATETALTCLVEKMNVFDTELKGLSKIE 439 Query: 554 R----NEVPEEKLYKVYT--FNSVRKSMSTVIRNPNGGFR-----MYSKGASEIILRKCN 602 R N V ++ + K +T F+ RKSMS V PN R M+ KGA E ++ +C Sbjct: 440 RANACNSVIKQLMKKEFTLEFSRDRKSMS-VYCTPNKPSRTSMSKMFVKGAPEGVIDRCT 498 Query: 603 RILDRKGEA-VPFKNKDRDDMVRTVIE-PMACDGLRTICIAYRDFDDTEPSW---DNENE 657 I R G VP + + ++ + E D LR + +A D D+ N Sbjct: 499 HI--RVGSTKVPMTSGVKQKIMSVIREWGSGSDTLRCLALATHDNPLRREEMHLEDSANF 556 Query: 658 IL--TELTCIAVVGIEDPVRPEVPDAIAKCKQAGITVRMVTGDNINTARAIATKCGILTP 715 I T LT + VG+ DP R EV ++ C+QAGI V M+TGDN TA AI + GI Sbjct: 557 IKYETNLTFVGCVGMLDPPRIEVASSVKLCRQAGIRVIMITGDNKGTAVAICRRIGIFGQ 616 Query: 716 GDDFL--CLEGKEFNRLIRNEKGEVEQEKLDKIWPKLRVLARSSPTDKHTLVKGIIDSTV 773 +D G+EF+ L + + + R AR P+ K +V+ + Sbjct: 617 DEDVTSKAFTGREFDELNPSAQRDA--------CLNARCFARVEPSHKSKIVEFL----- 663 Query: 774 GEHRQVVAVTGDGTNDGPALKKADVGFAMGIAGTDVAKEASDIILTDDNFTSIVKAVMWG 833 ++ A+TGDG ND PALKKA++G AMG +GT VAK AS+++L DDNF++IV AV G Sbjct: 664 QSFDEITAMTGDGVNDAPALKKAEIGIAMG-SGTAVAKTASEMVLADDNFSTIVAAVEEG 722 Query: 834 RNVYDSISKFLQFQLTVNVVAVIVAFTGACITQDSPLKAVQMLWVNLIMDTFASLALATE 893 R +Y+++ +F+++ ++ NV V+ F A + L VQ+LWVNL+ D + AL Sbjct: 723 RAIYNNMKQFIRYLISSNVGEVVCIFLTAALGFPEALIPVQLLWVNLVTDGLPATALGFN 782 Query: 894 PPTESLLKRRPYGRNKPLISRTMMKNILGHAFYQLIVI-------FILVFAGEK--FFDI 944 PP ++ + P +PLIS + L Y FI G + F+ + Sbjct: 783 PPDLDIMNKPPRNPKEPLISGWLFFRYLAIGCYVGAATVGAAAWWFIAADGGPRVSFYQL 842 Query: 945 DSGRKAPLHSPPSQ-----------HYTIVFNTFVLMQLFNEINSRKIHGEKNVFSGIYR 993 + +P + T+ + V +++ N +NS + + + Sbjct: 843 SHFLQCKEDNPDFEGVDCAIFESPYPMTMALSVLVTIEMCNALNSLS-ENQSLLRMPPWE 901 Query: 994 NIIFCSVVLGTFICQIFIVEFGGKP--FSCTSLSLSQWLWCLFIGIGELLWGQFISAIPT 1051 NI + + I+ P F T L+++QWL L I + +L + + + Sbjct: 902 NIWLVGSICLSMSLHFLILYVEPLPLIFQITPLNVTQWLMVLKISLPVILMDETLKFVAR 961 Query: 1052 RSLKFLKEAGHGTTK 1066 L+ KE TK Sbjct: 962 NYLEPGKECVQPATK 976 >gi|83700225 hydrogen/potassium-exchanging ATPase 12A [Homo sapiens] Length = 1039 Score = 246 bits (628), Expect = 9e-65 Identities = 231/798 (28%), Positives = 371/798 (46%), Gaps = 143/798 (17%) Query: 161 IVVLVTAFNDWSKEKQFRGLQCRIEQ--EQKFSIIRNGQLIQLPVAEIVVGDIAQVKYGD 218 +VV++T + +E + + + Q+ +IR+ + +P ++VVGDI +VK GD Sbjct: 153 LVVILTGIFAYYQEAKSTNIMSSFNKMIPQQALVIRDSEKKTIPSEQLVVGDIVEVKGGD 212 Query: 219 -------LLPADGILIQGNDLKIDESSLTGESDHVKKS-LDKDPMLLSGTHVMEGSGRMV 270 +L + G + + L + S+ ++ L+ + T +EG+ Sbjct: 213 QIPADIRVLSSQGCRVDNSSLTGESEPQPRSSEFTHENPLETKNICFYSTTCLEGT---- 268 Query: 271 VTAVGVNSQTGIILTLLGVNEDDEGEKKKKGKKQGVPENRNKAKTQDGVALEIQPLNSQE 330 VT + +N+ T++G I L S Sbjct: 269 VTGMVINTGDR---TIIG---------------------------------HIASLAS-- 290 Query: 331 GIDNEEKDKKAVKVPKKEKSVLQGKLTRLAVQIGKAGLLMSALTVFILILYFVIDNFVIN 390 G+ NE+ T +A++I +++ + V I IL+F+I Sbjct: 291 GVGNEK--------------------TPIAIEIEHFVHIVAGVAVSIGILFFII------ 324 Query: 391 RRPWLPECTPIYIQYFVKFFIIGITVLVVA-VPEGLPLAVTISLAYSVKKMMKDNNLVRH 449 + ++Y V II + ++VA VPEGL VT++L+ + K+M K N LV++ Sbjct: 325 ---------AVSLKYQVLDSIIFLIGIIVANVPEGLLATVTVTLSLTAKRMAKKNCLVKN 375 Query: 450 LDACETMGNATAICSDKTGTLTMNRMTVVQAYIGGIHYRQIPSPDVFLPKVLDLIVNGIS 509 L+A ET+G+ + ICSDKTGTLT NRMTV + + S D + + + S Sbjct: 376 LEAVETLGSTSIICSDKTGTLTQNRMTVAHLWFDNQIFVADTSEDHS-----NQVFDQSS 430 Query: 510 INSAYTSKIL---------PPEKEGGLPRQ--VGNKTECALLGFVTDLKQDYQAVRNEVP 558 A SKI+ P ++ + ++ +G+ +E ALL F + D +R Sbjct: 431 RTWASLSKIITLCNRAEFKPGQENVPIMKKAVIGDASETALLKFSEVILGDVMEIRKR-- 488 Query: 559 EEKLYKVYTFNSVRKSMSTV--IRNPNGG-FRMYSKGASEIILRKCNRILDRKGEAVPFK 615 K+ ++ FNS K ++ + +P+G F M KGA E IL KC+ I+ GE P Sbjct: 489 NRKVAEI-PFNSTNKFQLSIHEMDDPHGKRFLMVMKGAPERILEKCSTIMIN-GEEHPL- 545 Query: 616 NKDRDDMVRTVIEPMACDGLRTI--CIAYRDFDDTEPSW----DNENEILTELTCIAVVG 669 +K T + G R + C Y D+ ++ D N + L + ++ Sbjct: 546 DKSTAKTFHTAYMELGGLGERVLGFCHLYLPADEFPETYSFDIDAMNFPTSNLCFVGLLS 605 Query: 670 IEDPVRPEVPDAIAKCKQAGITVRMVTGDNINTARAIATKCGILTPGDDFLCLEGKEFNR 729 + DP R VPDA+ KC+ AGI V MVTGD+ TA+AIA GI++ + + N Sbjct: 606 MIDPPRSTVPDAVTKCRSAGIKVIMVTGDHPITAKAIAKSVGIISANSETVEDIAHRLNI 665 Query: 730 LIRN--------------EKGEVEQEKLDKIWPKLR--VLARSSPTDKHTLVKGIIDSTV 773 + E ++ E+LD+I + V AR+SP K +V+G Sbjct: 666 AVEQVNKRDAKAAVVTGMELKDMSSEQLDEILANYQEIVFARTSPQQKLIIVEGC----- 720 Query: 774 GEHRQ--VVAVTGDGTNDGPALKKADVGFAMGIAGTDVAKEASDIILTDDNFTSIVKAVM 831 RQ VVAVTGDG ND PALKKAD+G AMGIAG+D AK A+D++L DDNF SIV V Sbjct: 721 --QRQDAVVAVTGDGVNDSPALKKADIGIAMGIAGSDAAKNAADMVLLDDNFASIVTGVE 778 Query: 832 WGRNVYDSISKFLQFQLTVNVVAVIVAFTGACITQDSPLKAVQMLWVNLIMDTFASLALA 891 GR ++D++ K + + LT N+ + + P+ + +L+++L D S+ALA Sbjct: 779 EGRLIFDNLKKTIAYSLTKNIAELCPFLIYIIVGLPLPIGTITILFIDLGTDIIPSIALA 838 Query: 892 TEPPTESLLKRRPYGRNK 909 E ++ R+P +NK Sbjct: 839 YEKAESDIMNRKPRHKNK 856 >gi|118498343 ATPase, Ca++ transporting, type 2C, member 2 [Homo sapiens] Length = 946 Score = 243 bits (620), Expect = 8e-64 Identities = 190/627 (30%), Positives = 309/627 (49%), Gaps = 78/627 (12%) Query: 407 VKFFIIGITVLVVAVPEGLPLAVTISLAYSVKKMMKDNNLVRHLDACETMGNATAICSDK 466 + F IG+++ V A+PEGLP+ V ++L V +M K +V+ L ET+G + +CSDK Sbjct: 321 LSMFTIGVSLAVAAIPEGLPIVVMVTLVLGVLRMAKKRVIVKKLPIVETLGCCSVLCSDK 380 Query: 467 TGTLTMNRMTVVQ--------AYIGGIHYRQ------IPSPDVFLP----KVLDLIVNGI 508 TGTLT N MTV Q A + G+ Y +PS +V V L+ G Sbjct: 381 TGTLTANEMTVTQLVTSDGLRAEVSGVGYDGQGTVCLLPSKEVIKEFSNVSVGKLVEAGC 440 Query: 509 SINSAYTSKILPPEKEGGLPRQVGNKTECALLGFVTDLKQDYQAVRNEVPEEKLYKVYTF 568 N+A K +G TE AL+ +K D ++N +K F Sbjct: 441 VANNAVIRK----------NAVMGQPTEGALMALA--MKMDLSDIKNSYIRKK---EIPF 485 Query: 569 NSVRKSMSTV--IRNPNGGFRMYSKGASEIILRKCNRILDRKGEAVPFKNKDRDDMVRTV 626 +S +K M+ ++ + + KGA E ++R C + + G +P + R ++ Sbjct: 486 SSEQKWMAVKCSLKTEDQEDIYFMKGALEEVIRYCT-MYNNGGIPLPLTPQQRSFCLQEE 544 Query: 627 IEPMACDGLRTICIAYRDFDDTEPSWDNENEILTELTCIAVVGIEDPVRPEVPDAIAKCK 686 + M GLR + +A L LT + +VGI DP R V +A+ Sbjct: 545 -KRMGSLGLRVLALA-------------SGPELGRLTFLGLVGIIDPPRVGVKEAVQVLS 590 Query: 687 QAGITVRMVTGDNINTARAIATKCGILTPGDDFLCLEGKEFNRLIRNEKGEVEQEKLDKI 746 ++G++V+M+TGD + TA AI G+ + G+E + + EKGE+ D++ Sbjct: 591 ESGVSVKMITGDALETALAIGRNIGLCN--GKLQAMSGEEVDSV---EKGELA----DRV 641 Query: 747 WPKLRVLARSSPTDKHTLVKGIIDSTVGEHRQVVAVTGDGTNDGPALKKADVGFAMGIAG 806 K+ V R+SP K ++K + +S +VA+TGDG ND ALK AD+G AMG G Sbjct: 642 G-KVSVFFRTSPKHKLKIIKALQESGA-----IVAMTGDGVNDAVALKSADIGIAMGQTG 695 Query: 807 TDVAKEASDIILTDDNFTSIVKAVMWGRNVYDSISKFLQFQLTVNVVAVIVAFTGACITQ 866 TDV+KEA+++IL DD+F++I+ AV G+ ++ +I F++FQL+ ++ A+ + Sbjct: 696 TDVSKEAANMILVDDDFSAIMNAVEEGKGIFYNIKNFVRFQLSTSISALSLITLSTVFNL 755 Query: 867 DSPLKAVQMLWVNLIMDTFASLALATEPPTESLLKRRPYGRNKPLISRTMMKNILGHAFY 926 SPL A+Q+LW+N+IMD + +L EP + ++ P ++SR ++ IL A Sbjct: 756 PSPLNAMQILWINIIMDGPPAQSLGVEPVDKDAFRQPPRSVRDTILSRALILKILMSA-- 813 Query: 927 QLIVIFILVFAGEKFFDIDSGRKAPLHSPPSQHYTIVFNTFVLMQLFNEINSRKIHGEKN 986 ++ +G F + +P + T+ F FV LFN + R K Sbjct: 814 ------AIIISGTLFIFWKEMPEDRASTPRTT--TMTFTCFVFFDLFNALTCRS--QTKL 863 Query: 987 VFS-GIYRNIIFCSVVLGTFICQIFIV 1012 +F G RN +F VLG+ + Q+ ++ Sbjct: 864 IFEIGFLRNHMFLYSVLGSILGQLAVI 890 Score = 68.2 bits (165), Expect = 5e-11 Identities = 47/165 (28%), Positives = 77/165 (46%), Gaps = 12/165 (7%) Query: 151 EGAAILFSVIIVVLVTAFNDWSKEKQFRGLQCRIEQEQKFSIIRNGQLIQLPVAEIVVGD 210 + +I +V++VV V ++ EK L + E + +R G+L L E+V GD Sbjct: 133 DAVSIATAVLVVVTVAFIQEYRSEKSLEELTKMVPPE--CNCLREGKLQHLLARELVPGD 190 Query: 211 IAQVKYGDLLPADGILIQGNDLKIDESSLTGESDHVKKS----------LDKDPMLLSGT 260 + + GD +PAD L + DL +DESS TGE++ K+ ++ GT Sbjct: 191 VVSLSIGDRIPADIRLTEVTDLLVDESSFTGEAEPCSKTDSPLTGGGDLTTLSNIVFMGT 250 Query: 261 HVMEGSGRMVVTAVGVNSQTGIILTLLGVNEDDEGEKKKKGKKQG 305 V G G+ VV G +SQ G + ++ E + +K + G Sbjct: 251 LVQYGRGQGVVIGTGESSQFGEVFKMMQAEETPKTPLQKSMDRLG 295 >gi|237681109 Na+/K+ -ATPase alpha 1 subunit isoform c [Homo sapiens] Length = 1023 Score = 237 bits (605), Expect = 4e-62 Identities = 192/622 (30%), Positives = 303/622 (48%), Gaps = 76/622 (12%) Query: 350 SVLQGKLTRLAVQIGKAGLLMSALTVFILILYFVIDNFVINRRPWLPECTPIYIQYFVKF 409 S L+G T +A +I +++ + VF+ + +F++ +I WL Sbjct: 275 SGLEGGQTPIAAEIEHFIHIITGVAVFLGVSFFILS--LILEYTWLEAV----------I 322 Query: 410 FIIGITVLVVAVPEGLPLAVTISLAYSVKKMMKDNNLVRHLDACETMGNATAICSDKTGT 469 F+IGI +V VPEGL VT+ L + K+M + N LV++L+A ET+G+ + ICSDKTGT Sbjct: 323 FLIGI--IVANVPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGT 380 Query: 470 LTMNRMTVVQAYI-------------GGIHYRQIPSPDVFLPKVLDLIVNGISINSAYTS 516 LT NRMTV + G+ + + + + L ++ L + + Sbjct: 381 LTQNRMTVAHMWFDNQIHEADTTENQSGVSFDKTSATWLALSRIAGLCNRAVFQANQENL 440 Query: 517 KILPPEKEGGLPRQVGNKTECALLGFVTDLKQDYQAVRNEVPEEKLYKVYTFNSVRKSMS 576 IL G K G V ++++ Y + E+P FNS K Sbjct: 441 PILKRAVAGDASESALLKCIELCCGSVKEMRERYAKIV-EIP---------FNSTNKYQL 490 Query: 577 TVIRNPNGG---FRMYSKGASEIILRKCNRILDRKGEAVPFKNKDRDDMVRTVIEPMACD 633 ++ +NPN + KGA E IL +C+ IL G+ P + +D +E + Sbjct: 491 SIHKNPNTSEPQHLLVMKGAPERILDRCSSIL-LHGKEQPLDEELKDAFQNAYLE-LGGL 548 Query: 634 GLRTICIAYRDFDDTEP------SWDNENEILTELTCIAVVGIEDPVRPEVPDAIAKCKQ 687 G R + + D + D+ N + L + ++ + DP R VPDA+ KC+ Sbjct: 549 GERVLGFCHLFLPDEQFPEGFQFDTDDVNFPIDNLCFVGLISMIDPPRAAVPDAVGKCRS 608 Query: 688 AGITVRMVTGDNINTARAIATKCGILTPGDDFLCLEGKEFNRLI-----RNEKG------ 736 AGI V MVTGD+ TA+AIA GI++ G++ + N + R+ K Sbjct: 609 AGIKVIMVTGDHPITAKAIAKGVGIISEGNETVEDIAARLNIPVSQVNPRDAKACVVHGS 668 Query: 737 ---EVEQEKLDKI--WPKLRVLARSSPTDKHTLVKGIIDSTVGEHRQ--VVAVTGDGTND 789 ++ E+LD I + V AR+SP K +V+G RQ +VAVTGDG ND Sbjct: 669 DLKDMTSEQLDDILKYHTEIVFARTSPQQKLIIVEGC-------QRQGAIVAVTGDGVND 721 Query: 790 GPALKKADVGFAMGIAGTDVAKEASDIILTDDNFTSIVKAVMWGRNVYDSISKFLQFQLT 849 PALKKAD+G AMGIAG+DV+K+A+D+IL DDNF SIV V GR ++D++ K + + LT Sbjct: 722 SPALKKADIGVAMGIAGSDVSKQAADMILLDDNFASIVTGVEEGRLIFDNLKKSIAYTLT 781 Query: 850 VNVVAVIVAFTGACITQDSPLKAVQMLWVNLIMDTFASLALATEPPTESLLKRRPYGRNK 909 N+ + PL V +L ++L D +++LA E ++KR+P Sbjct: 782 SNIPEITPFLIFIIANIPLPLGTVTILCIDLGTDMVPAISLAYEQAESDIMKRQP---RN 838 Query: 910 PLISRTMMKNILGHAFYQLIVI 931 P + + + ++ A+ Q+ +I Sbjct: 839 PKTDKLVNERLISMAYGQIGMI 860 Score = 71.2 bits (173), Expect = 5e-12 Identities = 51/161 (31%), Positives = 80/161 (49%), Gaps = 13/161 (8%) Query: 134 QVATTPEDENEAQAGWIEGAAILFSVIIVVLVTAFNDWSKEKQFRGLQCRIEQEQKFSII 193 Q AT E +N+ G + VII + + + K + + Q+ +I Sbjct: 118 QAATEEEPQND---NLYLGVVLSAVVIITGCFSYYQEAKSSKIMESFKNMVPQQAL--VI 172 Query: 194 RNGQLIQLPVAEIVVGDIAQVKYGDLLPADGILIQGNDLKIDESSLTGESDHVKKSLD-- 251 RNG+ + + E+VVGD+ +VK GD +PAD +I N K+D SSLTGES+ +S D Sbjct: 173 RNGEKMSINAEEVVVGDLVEVKGGDRIPADLRIISANGCKVDNSSLTGESEPQTRSPDFT 232 Query: 252 -KDPM-----LLSGTHVMEGSGRMVVTAVGVNSQTGIILTL 286 ++P+ T+ +EG+ R +V G + G I TL Sbjct: 233 NENPLETRNIAFFSTNCVEGTARGIVVYTGDRTVMGRIATL 273 >gi|237681111 Na+/K+ -ATPase alpha 1 subunit isoform d [Homo sapiens] Length = 992 Score = 237 bits (605), Expect = 4e-62 Identities = 192/622 (30%), Positives = 303/622 (48%), Gaps = 76/622 (12%) Query: 350 SVLQGKLTRLAVQIGKAGLLMSALTVFILILYFVIDNFVINRRPWLPECTPIYIQYFVKF 409 S L+G T +A +I +++ + VF+ + +F++ +I WL Sbjct: 244 SGLEGGQTPIAAEIEHFIHIITGVAVFLGVSFFILS--LILEYTWLEAV----------I 291 Query: 410 FIIGITVLVVAVPEGLPLAVTISLAYSVKKMMKDNNLVRHLDACETMGNATAICSDKTGT 469 F+IGI +V VPEGL VT+ L + K+M + N LV++L+A ET+G+ + ICSDKTGT Sbjct: 292 FLIGI--IVANVPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGT 349 Query: 470 LTMNRMTVVQAYI-------------GGIHYRQIPSPDVFLPKVLDLIVNGISINSAYTS 516 LT NRMTV + G+ + + + + L ++ L + + Sbjct: 350 LTQNRMTVAHMWFDNQIHEADTTENQSGVSFDKTSATWLALSRIAGLCNRAVFQANQENL 409 Query: 517 KILPPEKEGGLPRQVGNKTECALLGFVTDLKQDYQAVRNEVPEEKLYKVYTFNSVRKSMS 576 IL G K G V ++++ Y + E+P FNS K Sbjct: 410 PILKRAVAGDASESALLKCIELCCGSVKEMRERYAKIV-EIP---------FNSTNKYQL 459 Query: 577 TVIRNPNGG---FRMYSKGASEIILRKCNRILDRKGEAVPFKNKDRDDMVRTVIEPMACD 633 ++ +NPN + KGA E IL +C+ IL G+ P + +D +E + Sbjct: 460 SIHKNPNTSEPQHLLVMKGAPERILDRCSSIL-LHGKEQPLDEELKDAFQNAYLE-LGGL 517 Query: 634 GLRTICIAYRDFDDTEP------SWDNENEILTELTCIAVVGIEDPVRPEVPDAIAKCKQ 687 G R + + D + D+ N + L + ++ + DP R VPDA+ KC+ Sbjct: 518 GERVLGFCHLFLPDEQFPEGFQFDTDDVNFPIDNLCFVGLISMIDPPRAAVPDAVGKCRS 577 Query: 688 AGITVRMVTGDNINTARAIATKCGILTPGDDFLCLEGKEFNRLI-----RNEKG------ 736 AGI V MVTGD+ TA+AIA GI++ G++ + N + R+ K Sbjct: 578 AGIKVIMVTGDHPITAKAIAKGVGIISEGNETVEDIAARLNIPVSQVNPRDAKACVVHGS 637 Query: 737 ---EVEQEKLDKI--WPKLRVLARSSPTDKHTLVKGIIDSTVGEHRQ--VVAVTGDGTND 789 ++ E+LD I + V AR+SP K +V+G RQ +VAVTGDG ND Sbjct: 638 DLKDMTSEQLDDILKYHTEIVFARTSPQQKLIIVEGC-------QRQGAIVAVTGDGVND 690 Query: 790 GPALKKADVGFAMGIAGTDVAKEASDIILTDDNFTSIVKAVMWGRNVYDSISKFLQFQLT 849 PALKKAD+G AMGIAG+DV+K+A+D+IL DDNF SIV V GR ++D++ K + + LT Sbjct: 691 SPALKKADIGVAMGIAGSDVSKQAADMILLDDNFASIVTGVEEGRLIFDNLKKSIAYTLT 750 Query: 850 VNVVAVIVAFTGACITQDSPLKAVQMLWVNLIMDTFASLALATEPPTESLLKRRPYGRNK 909 N+ + PL V +L ++L D +++LA E ++KR+P Sbjct: 751 SNIPEITPFLIFIIANIPLPLGTVTILCIDLGTDMVPAISLAYEQAESDIMKRQP---RN 807 Query: 910 PLISRTMMKNILGHAFYQLIVI 931 P + + + ++ A+ Q+ +I Sbjct: 808 PKTDKLVNERLISMAYGQIGMI 829 Score = 71.2 bits (173), Expect = 5e-12 Identities = 51/161 (31%), Positives = 80/161 (49%), Gaps = 13/161 (8%) Query: 134 QVATTPEDENEAQAGWIEGAAILFSVIIVVLVTAFNDWSKEKQFRGLQCRIEQEQKFSII 193 Q AT E +N+ G + VII + + + K + + Q+ +I Sbjct: 87 QAATEEEPQND---NLYLGVVLSAVVIITGCFSYYQEAKSSKIMESFKNMVPQQAL--VI 141 Query: 194 RNGQLIQLPVAEIVVGDIAQVKYGDLLPADGILIQGNDLKIDESSLTGESDHVKKSLD-- 251 RNG+ + + E+VVGD+ +VK GD +PAD +I N K+D SSLTGES+ +S D Sbjct: 142 RNGEKMSINAEEVVVGDLVEVKGGDRIPADLRIISANGCKVDNSSLTGESEPQTRSPDFT 201 Query: 252 -KDPM-----LLSGTHVMEGSGRMVVTAVGVNSQTGIILTL 286 ++P+ T+ +EG+ R +V G + G I TL Sbjct: 202 NENPLETRNIAFFSTNCVEGTARGIVVYTGDRTVMGRIATL 242 >gi|21361181 Na+/K+ -ATPase alpha 1 subunit isoform a [Homo sapiens] Length = 1023 Score = 237 bits (605), Expect = 4e-62 Identities = 192/622 (30%), Positives = 303/622 (48%), Gaps = 76/622 (12%) Query: 350 SVLQGKLTRLAVQIGKAGLLMSALTVFILILYFVIDNFVINRRPWLPECTPIYIQYFVKF 409 S L+G T +A +I +++ + VF+ + +F++ +I WL Sbjct: 275 SGLEGGQTPIAAEIEHFIHIITGVAVFLGVSFFILS--LILEYTWLEAV----------I 322 Query: 410 FIIGITVLVVAVPEGLPLAVTISLAYSVKKMMKDNNLVRHLDACETMGNATAICSDKTGT 469 F+IGI +V VPEGL VT+ L + K+M + N LV++L+A ET+G+ + ICSDKTGT Sbjct: 323 FLIGI--IVANVPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGT 380 Query: 470 LTMNRMTVVQAYI-------------GGIHYRQIPSPDVFLPKVLDLIVNGISINSAYTS 516 LT NRMTV + G+ + + + + L ++ L + + Sbjct: 381 LTQNRMTVAHMWFDNQIHEADTTENQSGVSFDKTSATWLALSRIAGLCNRAVFQANQENL 440 Query: 517 KILPPEKEGGLPRQVGNKTECALLGFVTDLKQDYQAVRNEVPEEKLYKVYTFNSVRKSMS 576 IL G K G V ++++ Y + E+P FNS K Sbjct: 441 PILKRAVAGDASESALLKCIELCCGSVKEMRERYAKIV-EIP---------FNSTNKYQL 490 Query: 577 TVIRNPNGG---FRMYSKGASEIILRKCNRILDRKGEAVPFKNKDRDDMVRTVIEPMACD 633 ++ +NPN + KGA E IL +C+ IL G+ P + +D +E + Sbjct: 491 SIHKNPNTSEPQHLLVMKGAPERILDRCSSIL-LHGKEQPLDEELKDAFQNAYLE-LGGL 548 Query: 634 GLRTICIAYRDFDDTEP------SWDNENEILTELTCIAVVGIEDPVRPEVPDAIAKCKQ 687 G R + + D + D+ N + L + ++ + DP R VPDA+ KC+ Sbjct: 549 GERVLGFCHLFLPDEQFPEGFQFDTDDVNFPIDNLCFVGLISMIDPPRAAVPDAVGKCRS 608 Query: 688 AGITVRMVTGDNINTARAIATKCGILTPGDDFLCLEGKEFNRLI-----RNEKG------ 736 AGI V MVTGD+ TA+AIA GI++ G++ + N + R+ K Sbjct: 609 AGIKVIMVTGDHPITAKAIAKGVGIISEGNETVEDIAARLNIPVSQVNPRDAKACVVHGS 668 Query: 737 ---EVEQEKLDKI--WPKLRVLARSSPTDKHTLVKGIIDSTVGEHRQ--VVAVTGDGTND 789 ++ E+LD I + V AR+SP K +V+G RQ +VAVTGDG ND Sbjct: 669 DLKDMTSEQLDDILKYHTEIVFARTSPQQKLIIVEGC-------QRQGAIVAVTGDGVND 721 Query: 790 GPALKKADVGFAMGIAGTDVAKEASDIILTDDNFTSIVKAVMWGRNVYDSISKFLQFQLT 849 PALKKAD+G AMGIAG+DV+K+A+D+IL DDNF SIV V GR ++D++ K + + LT Sbjct: 722 SPALKKADIGVAMGIAGSDVSKQAADMILLDDNFASIVTGVEEGRLIFDNLKKSIAYTLT 781 Query: 850 VNVVAVIVAFTGACITQDSPLKAVQMLWVNLIMDTFASLALATEPPTESLLKRRPYGRNK 909 N+ + PL V +L ++L D +++LA E ++KR+P Sbjct: 782 SNIPEITPFLIFIIANIPLPLGTVTILCIDLGTDMVPAISLAYEQAESDIMKRQP---RN 838 Query: 910 PLISRTMMKNILGHAFYQLIVI 931 P + + + ++ A+ Q+ +I Sbjct: 839 PKTDKLVNERLISMAYGQIGMI 860 Score = 71.2 bits (173), Expect = 5e-12 Identities = 51/161 (31%), Positives = 80/161 (49%), Gaps = 13/161 (8%) Query: 134 QVATTPEDENEAQAGWIEGAAILFSVIIVVLVTAFNDWSKEKQFRGLQCRIEQEQKFSII 193 Q AT E +N+ G + VII + + + K + + Q+ +I Sbjct: 118 QAATEEEPQND---NLYLGVVLSAVVIITGCFSYYQEAKSSKIMESFKNMVPQQAL--VI 172 Query: 194 RNGQLIQLPVAEIVVGDIAQVKYGDLLPADGILIQGNDLKIDESSLTGESDHVKKSLD-- 251 RNG+ + + E+VVGD+ +VK GD +PAD +I N K+D SSLTGES+ +S D Sbjct: 173 RNGEKMSINAEEVVVGDLVEVKGGDRIPADLRIISANGCKVDNSSLTGESEPQTRSPDFT 232 Query: 252 -KDPM-----LLSGTHVMEGSGRMVVTAVGVNSQTGIILTL 286 ++P+ T+ +EG+ R +V G + G I TL Sbjct: 233 NENPLETRNIAFFSTNCVEGTARGIVVYTGDRTVMGRIATL 273 >gi|153946397 Na+/K+ -ATPase alpha 4 subunit isoform 1 [Homo sapiens] Length = 1029 Score = 225 bits (574), Expect = 2e-58 Identities = 186/611 (30%), Positives = 300/611 (49%), Gaps = 70/611 (11%) Query: 357 TRLAVQIGKAGLLMSALTVFILILYFVIDNFVINRRPWLPECTPIYIQYFVKFFIIGITV 416 T +A +I L++ + VF+ + +F + ++ WL F+IGI Sbjct: 290 TPIAAEIEHFIHLITVVAVFLGVTFFALS--LLLGYGWLEAI----------IFLIGI-- 335 Query: 417 LVVAVPEGLPLAVTISLAYSVKKMMKDNNLVRHLDACETMGNATAICSDKTGTLTMNRMT 476 +V VPEGL VT+ L + K+M + N LV++L+A ET+G+ + ICSDKTGTLT NRMT Sbjct: 336 IVANVPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRMT 395 Query: 477 VVQAYIGGIHYRQIPSPDV------------FLPKVLDLIVNGISINSAYTSKILPPEKE 524 V + Y + + F+ + + N + +ILP K Sbjct: 396 VAHMWFDMTVYEADTTEEQTGKTFTKSSDTWFMLARIAGLCNRADFKA--NQEILPIAKR 453 Query: 525 GGLPRQVGNKTECALLGFVTDLKQDYQAVRNEVPEEKLYKVYTFNSVRK-SMSTVIRNPN 583 G+ +E ALL F+ +Q Y +V + FNS K MS +R + Sbjct: 454 A----TTGDASESALLKFI---EQSYSSVAEMREKNPKVAEIPFNSTNKYQMSIHLREDS 506 Query: 584 GGFR-MYSKGASEIILRKCNRILDRKGEAVPFKNKDRDDMVRTVIEPMACDGLRTICIAY 642 + KGA E IL C+ L G+ ++ ++ +E + G R + + Sbjct: 507 SQTHVLMMKGAPERILEFCSTFL-LNGQEYSMNDEMKEAFQNAYLE-LGGLGERVLGFCF 564 Query: 643 RDFDDTEP-----SWDNENEILTELTCIAVVGIEDPVRPEVPDAIAKCKQAGITVRMVTG 697 + + + D N + L + ++ + DP R VPDA++KC+ AGI V MVTG Sbjct: 565 LNLPSSFSKGFPFNTDEINFPMDNLCFVGLISMIDPPRAAVPDAVSKCRSAGIKVIMVTG 624 Query: 698 DNINTARAIATKCGILTPGDD------------FLCLEGKEFNRLIRN--EKGEVEQEKL 743 D+ TA+AIA GI++ G + ++ ++ + E +++ ++L Sbjct: 625 DHPITAKAIAKGVGIISEGTETAEEVAARLKIPISKVDASAAKAIVVHGAELKDIQSKQL 684 Query: 744 DKIW---PKLRVLARSSPTDKHTLVKGIIDSTVGEHRQVVAVTGDGTNDGPALKKADVGF 800 D+I P++ V AR+SP K +V+G +G VVAVTGDG ND PALKKAD+G Sbjct: 685 DQILQNHPEI-VFARTSPQQKLIIVEGC--QRLGA---VVAVTGDGVNDSPALKKADIGI 738 Query: 801 AMGIAGTDVAKEASDIILTDDNFTSIVKAVMWGRNVYDSISKFLQFQLTVNVVAVIVAFT 860 AMGI+G+DV+K+A+D+IL DDNF SIV V GR ++D++ K + + LT N+ + Sbjct: 739 AMGISGSDVSKQAADMILLDDNFASIVTGVEEGRLIFDNLKKSIMYTLTSNIPEITPFLM 798 Query: 861 GACITQDSPLKAVQMLWVNLIMDTFASLALATEPPTESLLKRRPYGRNKPLISRTMMKNI 920 + PL + +L ++L D +++LA E ++KR P P + + Sbjct: 799 FIILGIPLPLGTITILCIDLGTDMVPAISLAYESAESDIMKRLP---RNPKTDNLVNHRL 855 Query: 921 LGHAFYQLIVI 931 +G A+ Q+ +I Sbjct: 856 IGMAYGQIGMI 866 Score = 69.7 bits (169), Expect = 2e-11 Identities = 46/142 (32%), Positives = 82/142 (57%), Gaps = 10/142 (7%) Query: 154 AILFSVIIVVLVTAFNDWSKEKQFRGLQC-RIEQEQKFSIIRNGQLIQLPVAEIVVGDIA 212 +I+ SV+++V F+ + + K + ++ + Q+ +IR G+ +Q+ V E+V+GD+ Sbjct: 141 SIVLSVVVIV-TGCFSYYQEAKSSKIMESFKNMVPQQALVIRGGEKMQINVQEVVLGDLV 199 Query: 213 QVKYGDLLPADGILIQGNDLKIDESSLTGESDHVKKSLD---KDPM-----LLSGTHVME 264 ++K GD +PAD LI K+D SSLTGES+ +S D ++P+ T+ +E Sbjct: 200 EIKGGDRVPADLRLISAQGCKVDNSSLTGESEPQSRSPDFTHENPLETRNICFFSTNCVE 259 Query: 265 GSGRMVVTAVGVNSQTGIILTL 286 G+ R +V A G ++ G I +L Sbjct: 260 GTARGIVIATGDSTVMGRIASL 281 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.319 0.136 0.397 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 44,611,214 Number of Sequences: 37866 Number of extensions: 2006494 Number of successful extensions: 5886 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 67 Number of HSP's successfully gapped in prelim test: 13 Number of HSP's that attempted gapping in prelim test: 5496 Number of HSP's gapped (non-prelim): 212 length of query: 1205 length of database: 18,247,518 effective HSP length: 114 effective length of query: 1091 effective length of database: 13,930,794 effective search space: 15198496254 effective search space used: 15198496254 T: 11 A: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.