Search of human proteins with 4758714

Search of human proteins with 4758714

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|4758714 microsomal glutathione S-transferase 3 [Homo
sapiens]
         (152 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|4758714 microsomal glutathione S-transferase 3 [Homo sapiens]      315   7e-87
gi|4505181 microsomal glutathione S-transferase 2 [Homo sapiens]       62   2e-10
gi|4758910 prostaglandin E synthase [Homo sapiens]                     31   0.46 
gi|15718675 arachidonate 5-lipoxygenase-activating protein [Homo...    31   0.46 
gi|38569457 solute carrier family 12, member 8 [Homo sapiens]          28   2.3  
gi|73747889 a disintegrin and metalloprotease domain 17 prepropr...    27   6.7  
gi|221307568 DENN/MADD domain containing 4A isoform 1 [Homo sapi...    27   8.8  
gi|221307566 DENN/MADD domain containing 4A isoform 2 [Homo sapi...    27   8.8  
gi|239757727 PREDICTED: similar to hCG2013141 [Homo sapiens]           27   8.8  
gi|239752218 PREDICTED: hypothetical protein XP_002348134 [Homo ...    27   8.8  
gi|14211941 gap junction protein, alpha 10 [Homo sapiens]              27   8.8  

>gi|4758714 microsomal glutathione S-transferase 3 [Homo sapiens]
          Length = 152

 Score =  315 bits (808), Expect = 7e-87
 Identities = 152/152 (100%), Positives = 152/152 (100%)

Query: 1   MAVLSKEYGFVLLTGAASFIMVAHLAINVSKARKKYKVEYPIMYSTDPENGHIFNCIQRA 60
           MAVLSKEYGFVLLTGAASFIMVAHLAINVSKARKKYKVEYPIMYSTDPENGHIFNCIQRA
Sbjct: 1   MAVLSKEYGFVLLTGAASFIMVAHLAINVSKARKKYKVEYPIMYSTDPENGHIFNCIQRA 60

Query: 61  HQNTLEVYPPFLFFLAVGGVYHPRIASGLGLAWIVGRVLYAYGYYTGEPSKRSRGALGSI 120
           HQNTLEVYPPFLFFLAVGGVYHPRIASGLGLAWIVGRVLYAYGYYTGEPSKRSRGALGSI
Sbjct: 61  HQNTLEVYPPFLFFLAVGGVYHPRIASGLGLAWIVGRVLYAYGYYTGEPSKRSRGALGSI 120

Query: 121 ALLGLVGTTVCSAFQHLGWVKSGLGSGPKCCH 152
           ALLGLVGTTVCSAFQHLGWVKSGLGSGPKCCH
Sbjct: 121 ALLGLVGTTVCSAFQHLGWVKSGLGSGPKCCH 152


>gi|4505181 microsomal glutathione S-transferase 2 [Homo sapiens]
          Length = 147

 Score = 62.0 bits (149), Expect = 2e-10
 Identities = 49/127 (38%), Positives = 70/127 (55%), Gaps = 15/127 (11%)

Query: 9   GFVLLTGAASFIMV---AHLAINVSKARKKYKVEYPIMYSTDPENGHIFNCIQRAHQNTL 65
           G  +L  A S +     ++ A+ V KAR KYKV  P +  + PE   +F    RA QN +
Sbjct: 3   GNSILLAAVSILSACQQSYFALQVGKARLKYKVTPPAVTGS-PEFERVF----RAQQNCV 57

Query: 66  EVYPPFLFFLAVGGVYHPRI-ASGLGLAWIVGRVLYAYGYYTGEPSKRS----RGALGSI 120
           E YP F+  L + G Y  ++ A+ LGL +I GR LY +GY   E +K+     R +LG +
Sbjct: 58  EFYPIFIITLWMAGWYFNQVFATCLGLVYIYGRHLYFWGY--SEAAKKRITGFRLSLGIL 115

Query: 121 ALLGLVG 127
           ALL L+G
Sbjct: 116 ALLTLLG 122


>gi|4758910 prostaglandin E synthase [Homo sapiens]
          Length = 152

 Score = 30.8 bits (68), Expect = 0.46
 Identities = 23/64 (35%), Positives = 35/64 (54%), Gaps = 12/64 (18%)

Query: 46  TDPENGHIFNCIQRAHQNTLEVYPPFLFFLAVGGVY-----HPRIASGLGLAWIVGRVLY 100
           +DP+   +  C+ RAH+N +E   PFLF   +G VY     +P +A    L ++VGRV +
Sbjct: 61  SDPD---VERCL-RAHRNDMETIYPFLF---LGFVYSFLGPNPFVAWMHFLVFLVGRVAH 113

Query: 101 AYGY 104
              Y
Sbjct: 114 TVAY 117


>gi|15718675 arachidonate 5-lipoxygenase-activating protein [Homo
           sapiens]
          Length = 161

 Score = 30.8 bits (68), Expect = 0.46
 Identities = 25/85 (29%), Positives = 42/85 (49%), Gaps = 3/85 (3%)

Query: 54  FNCIQRAHQNTLEVYPPFLFFLAVGGVYHPRI-ASGLGLAWIVGRVLYAYGYYTGEPSKR 112
           F  +  A+QN ++ YP FL  L   G+   ++ A+  GL ++  R  Y  G Y GE ++ 
Sbjct: 50  FERVYTANQNCVDAYPTFLAVLWSAGLLCSQVPAAFAGLMYLFVRQKYFVG-YLGERTQS 108

Query: 113 SRGAL-GSIALLGLVGTTVCSAFQH 136
           + G + G   +L L   +V   F +
Sbjct: 109 TPGYIFGKRIILFLFLMSVAGIFNY 133


>gi|38569457 solute carrier family 12, member 8 [Homo sapiens]
          Length = 714

 Score = 28.5 bits (62), Expect = 2.3
 Identities = 26/79 (32%), Positives = 38/79 (48%), Gaps = 10/79 (12%)

Query: 47  DPENGHIFNCIQRAHQNTLEVYPPFLFFLAVGGVYHPRIASGLGLAWIVGRVLYAYGYYT 106
           DPE+G I    +    NTL  Y P   F  V GV+ P  A+G+   + +G  L       
Sbjct: 206 DPEHGFIGYSPELLQNNTLPDYSPGESFFTVFGVFFP-AATGVMAGFNMGGDL------- 257

Query: 107 GEPSKRSRGALGSIALLGL 125
            EP+  +   LGS+A +G+
Sbjct: 258 REPA--ASIPLGSLAAVGI 274


>gi|73747889 a disintegrin and metalloprotease domain 17
           preproprotein [Homo sapiens]
          Length = 824

 Score = 26.9 bits (58), Expect = 6.7
 Identities = 23/78 (29%), Positives = 31/78 (39%), Gaps = 17/78 (21%)

Query: 5   SKEYGFVLLTGAASFIMVAHLAINVSKARK---------------KYKVEYPIMYSTDPE 49
           +K YG  +LT  A  +    L  N                     KY V YPI  S D E
Sbjct: 387 TKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKY-VMYPIAVSGDHE 445

Query: 50  NGHIF-NCIQRAHQNTLE 66
           N  +F NC +++   T+E
Sbjct: 446 NNKMFSNCSKQSIYKTIE 463


>gi|221307568 DENN/MADD domain containing 4A isoform 1 [Homo
           sapiens]
          Length = 1906

 Score = 26.6 bits (57), Expect = 8.8
 Identities = 12/27 (44%), Positives = 16/27 (59%)

Query: 50  NGHIFNCIQRAHQNTLEVYPPFLFFLA 76
           N + FN  +R H   LE+   FLFF+A
Sbjct: 545 NDYDFNSGKRLHMIDLEIQEAFLFFMA 571


>gi|221307566 DENN/MADD domain containing 4A isoform 2 [Homo
           sapiens]
          Length = 1863

 Score = 26.6 bits (57), Expect = 8.8
 Identities = 12/27 (44%), Positives = 16/27 (59%)

Query: 50  NGHIFNCIQRAHQNTLEVYPPFLFFLA 76
           N + FN  +R H   LE+   FLFF+A
Sbjct: 545 NDYDFNSGKRLHMIDLEIQEAFLFFMA 571


>gi|239757727 PREDICTED: similar to hCG2013141 [Homo sapiens]
          Length = 133

 Score = 26.6 bits (57), Expect = 8.8
 Identities = 14/39 (35%), Positives = 17/39 (43%)

Query: 114 RGALGSIALLGLVGTTVCSAFQHLGWVKSGLGSGPKCCH 152
           RG  GS +  GL   T       L  + +G GSG   CH
Sbjct: 52  RGGTGSPSTAGLPALTTLELSPGLSHLPAGQGSGLAACH 90


>gi|239752218 PREDICTED: hypothetical protein XP_002348134 [Homo
           sapiens]
          Length = 133

 Score = 26.6 bits (57), Expect = 8.8
 Identities = 14/39 (35%), Positives = 17/39 (43%)

Query: 114 RGALGSIALLGLVGTTVCSAFQHLGWVKSGLGSGPKCCH 152
           RG  GS +  GL   T       L  + +G GSG   CH
Sbjct: 52  RGGTGSPSTAGLPALTTLELSPGLSHLPAGQGSGLAACH 90


>gi|14211941 gap junction protein, alpha 10 [Homo sapiens]
          Length = 543

 Score = 26.6 bits (57), Expect = 8.8
 Identities = 12/46 (26%), Positives = 21/46 (45%)

Query: 25  LAINVSKARKKYKVEYPIMYSTDPENGHIFNCIQRAHQNTLEVYPP 70
           + +NV K++  +++  P     DP NG      +  H   L V+ P
Sbjct: 292 IRVNVPKSKTMWQIPQPRQLEVDPSNGKKDWSEKDQHSGQLHVHSP 337


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.324    0.140    0.445 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 5,949,539
Number of Sequences: 37866
Number of extensions: 244404
Number of successful extensions: 572
Number of sequences better than 10.0: 11
Number of HSP's better than 10.0 without gapping: 7
Number of HSP's successfully gapped in prelim test: 4
Number of HSP's that attempted gapping in prelim test: 563
Number of HSP's gapped (non-prelim): 11
length of query: 152
length of database: 18,247,518
effective HSP length: 93
effective length of query: 59
effective length of database: 14,725,980
effective search space: 868832820
effective search space used: 868832820
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.5 bits)
S2: 57 (26.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.