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Search of human proteins with 47458041
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|47458041 solute carrier family 25 member 24 isoform 2 [Homo
sapiens]
(458 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|47458041 solute carrier family 25 member 24 isoform 2 [Homo s... 922 0.0
gi|148491091 solute carrier family 25 member 24 isoform 1 [Homo ... 864 0.0
gi|239755174 PREDICTED: similar to solute carrier family 25, mem... 603 e-172
gi|56699403 solute carrier family 25, member 25 isoform b [Homo ... 603 e-172
gi|48476342 solute carrier family 25, member 23 [Homo sapiens] 594 e-170
gi|56699407 solute carrier family 25, member 25 isoform c [Homo ... 585 e-167
gi|239755176 PREDICTED: similar to solute carrier family 25, mem... 584 e-167
gi|56699401 solute carrier family 25, member 25 isoform a [Homo ... 584 e-167
gi|56699405 solute carrier family 25, member 25 isoform d [Homo ... 514 e-146
gi|149274607 solute carrier family 25, member 41 [Homo sapiens] 320 2e-87
gi|27544933 solute carrier family 25, member 16 [Homo sapiens] 182 4e-46
gi|60460887 solute carrier family 25, member 42 [Homo sapiens] 181 1e-45
gi|156071462 solute carrier family 25, member A6 [Homo sapiens] 137 2e-32
gi|13775208 solute carrier family 25 (mitochondrial carrier; ade... 132 7e-31
gi|55749577 solute carrier family 25 (mitochondrial carrier; ade... 131 1e-30
gi|156071459 solute carrier family 25, member 5 [Homo sapiens] 131 1e-30
gi|21687151 mitochondrial solute carrier protein [Homo sapiens] 127 2e-29
gi|21314739 solute carrier family 25, member 32 [Homo sapiens] 119 7e-27
gi|186928856 solute carrier family 25, member 19 [Homo sapiens] 109 5e-24
gi|186928860 solute carrier family 25, member 19 [Homo sapiens] 109 5e-24
gi|186928858 solute carrier family 25, member 19 [Homo sapiens] 109 5e-24
gi|157388989 solute carrier family 25, member 36 isoform a [Homo... 108 1e-23
gi|157388991 solute carrier family 25, member 36 isoform b [Homo... 104 1e-22
gi|4507009 solute carrier family 25, member 14 isoform UCP5L [Ho... 104 1e-22
gi|13259543 solute carrier family 25, member 14 isoform UCP5S [H... 104 1e-22
gi|21361103 solute carrier family 25, member 12 [Homo sapiens] 102 7e-22
gi|46094065 mitochondrial carrier family protein [Homo sapiens] 100 3e-21
gi|58197562 solute carrier family 25, member 30 [Homo sapiens] 98 1e-20
gi|82775373 solute carrier family 25, member 37 [Homo sapiens] 97 2e-20
gi|7706306 solute carrier family 25, member 39 isoform b [Homo s... 97 2e-20
>gi|47458041 solute carrier family 25 member 24 isoform 2 [Homo
sapiens]
Length = 458
Score = 922 bits (2382), Expect = 0.0
Identities = 458/458 (100%), Positives = 458/458 (100%)
Query: 1 MDSLYGDLFWYLDYNKDGTLDIFELQEGLEDVGAIQSLEEAKKIFTTGDVNKDGKLDFEE 60
MDSLYGDLFWYLDYNKDGTLDIFELQEGLEDVGAIQSLEEAKKIFTTGDVNKDGKLDFEE
Sbjct: 1 MDSLYGDLFWYLDYNKDGTLDIFELQEGLEDVGAIQSLEEAKKIFTTGDVNKDGKLDFEE 60
Query: 61 FMKYLKDHEKKMKLAFKSLDKNNDGKIEASEIVQSLQTLGLTISEQQAELILQSIDVDGT 120
FMKYLKDHEKKMKLAFKSLDKNNDGKIEASEIVQSLQTLGLTISEQQAELILQSIDVDGT
Sbjct: 61 FMKYLKDHEKKMKLAFKSLDKNNDGKIEASEIVQSLQTLGLTISEQQAELILQSIDVDGT 120
Query: 121 MTVDWNEWRDYFLFNPVTDIEEIIRFWKHSTGIDIGDSLTIPDEFTEDEKKSGQWWRQLL 180
MTVDWNEWRDYFLFNPVTDIEEIIRFWKHSTGIDIGDSLTIPDEFTEDEKKSGQWWRQLL
Sbjct: 121 MTVDWNEWRDYFLFNPVTDIEEIIRFWKHSTGIDIGDSLTIPDEFTEDEKKSGQWWRQLL 180
Query: 181 AGGIAGAVSRTSTAPLDRLKIMMQVHGSKSDKMNIFGGFRQMVKEGGIRSLWRGNGTNVI 240
AGGIAGAVSRTSTAPLDRLKIMMQVHGSKSDKMNIFGGFRQMVKEGGIRSLWRGNGTNVI
Sbjct: 181 AGGIAGAVSRTSTAPLDRLKIMMQVHGSKSDKMNIFGGFRQMVKEGGIRSLWRGNGTNVI 240
Query: 241 KIAPETAVKFWAYEQYKKLLTEEGQKIGTFERFISGSMAGATAQTFIYPMEVMKTRLAVG 300
KIAPETAVKFWAYEQYKKLLTEEGQKIGTFERFISGSMAGATAQTFIYPMEVMKTRLAVG
Sbjct: 241 KIAPETAVKFWAYEQYKKLLTEEGQKIGTFERFISGSMAGATAQTFIYPMEVMKTRLAVG 300
Query: 301 KTGQYSGIYDCAKKILKHEGLGAFYKGYVPNLLGIIPYAGIDLAVYELLKSYWLDNFAKD 360
KTGQYSGIYDCAKKILKHEGLGAFYKGYVPNLLGIIPYAGIDLAVYELLKSYWLDNFAKD
Sbjct: 301 KTGQYSGIYDCAKKILKHEGLGAFYKGYVPNLLGIIPYAGIDLAVYELLKSYWLDNFAKD 360
Query: 361 SVNPGVMVLLGCGALSSTCGQLASYPLALVRTRMQAQAMLEGSPQLNMVGLFRRIISKEG 420
SVNPGVMVLLGCGALSSTCGQLASYPLALVRTRMQAQAMLEGSPQLNMVGLFRRIISKEG
Sbjct: 361 SVNPGVMVLLGCGALSSTCGQLASYPLALVRTRMQAQAMLEGSPQLNMVGLFRRIISKEG 420
Query: 421 IPGLYRGITPNFMKVLPAVGISYVVYENMKQTLGVTQK 458
IPGLYRGITPNFMKVLPAVGISYVVYENMKQTLGVTQK
Sbjct: 421 IPGLYRGITPNFMKVLPAVGISYVVYENMKQTLGVTQK 458
>gi|148491091 solute carrier family 25 member 24 isoform 1 [Homo
sapiens]
Length = 477
Score = 864 bits (2233), Expect = 0.0
Identities = 433/454 (95%), Positives = 438/454 (96%)
Query: 5 YGDLFWYLDYNKDGTLDIFELQEGLEDVGAIQSLEEAKKIFTTGDVNKDGKLDFEEFMKY 64
Y LF LD N DG +DI ELQEGL ++G + +KIFTTGDVNKDGKLDFEEFMKY
Sbjct: 24 YETLFQALDRNGDGVVDIGELQEGLRNLGIPLGQDAEEKIFTTGDVNKDGKLDFEEFMKY 83
Query: 65 LKDHEKKMKLAFKSLDKNNDGKIEASEIVQSLQTLGLTISEQQAELILQSIDVDGTMTVD 124
LKDHEKKMKLAFKSLDKNNDGKIEASEIVQSLQTLGLTISEQQAELILQSIDVDGTMTVD
Sbjct: 84 LKDHEKKMKLAFKSLDKNNDGKIEASEIVQSLQTLGLTISEQQAELILQSIDVDGTMTVD 143
Query: 125 WNEWRDYFLFNPVTDIEEIIRFWKHSTGIDIGDSLTIPDEFTEDEKKSGQWWRQLLAGGI 184
WNEWRDYFLFNPVTDIEEIIRFWKHSTGIDIGDSLTIPDEFTEDEKKSGQWWRQLLAGGI
Sbjct: 144 WNEWRDYFLFNPVTDIEEIIRFWKHSTGIDIGDSLTIPDEFTEDEKKSGQWWRQLLAGGI 203
Query: 185 AGAVSRTSTAPLDRLKIMMQVHGSKSDKMNIFGGFRQMVKEGGIRSLWRGNGTNVIKIAP 244
AGAVSRTSTAPLDRLKIMMQVHGSKSDKMNIFGGFRQMVKEGGIRSLWRGNGTNVIKIAP
Sbjct: 204 AGAVSRTSTAPLDRLKIMMQVHGSKSDKMNIFGGFRQMVKEGGIRSLWRGNGTNVIKIAP 263
Query: 245 ETAVKFWAYEQYKKLLTEEGQKIGTFERFISGSMAGATAQTFIYPMEVMKTRLAVGKTGQ 304
ETAVKFWAYEQYKKLLTEEGQKIGTFERFISGSMAGATAQTFIYPMEVMKTRLAVGKTGQ
Sbjct: 264 ETAVKFWAYEQYKKLLTEEGQKIGTFERFISGSMAGATAQTFIYPMEVMKTRLAVGKTGQ 323
Query: 305 YSGIYDCAKKILKHEGLGAFYKGYVPNLLGIIPYAGIDLAVYELLKSYWLDNFAKDSVNP 364
YSGIYDCAKKILKHEGLGAFYKGYVPNLLGIIPYAGIDLAVYELLKSYWLDNFAKDSVNP
Sbjct: 324 YSGIYDCAKKILKHEGLGAFYKGYVPNLLGIIPYAGIDLAVYELLKSYWLDNFAKDSVNP 383
Query: 365 GVMVLLGCGALSSTCGQLASYPLALVRTRMQAQAMLEGSPQLNMVGLFRRIISKEGIPGL 424
GVMVLLGCGALSSTCGQLASYPLALVRTRMQAQAMLEGSPQLNMVGLFRRIISKEGIPGL
Sbjct: 384 GVMVLLGCGALSSTCGQLASYPLALVRTRMQAQAMLEGSPQLNMVGLFRRIISKEGIPGL 443
Query: 425 YRGITPNFMKVLPAVGISYVVYENMKQTLGVTQK 458
YRGITPNFMKVLPAVGISYVVYENMKQTLGVTQK
Sbjct: 444 YRGITPNFMKVLPAVGISYVVYENMKQTLGVTQK 477
>gi|239755174 PREDICTED: similar to solute carrier family 25, member
25 isoform 1 [Homo sapiens]
Length = 503
Score = 603 bits (1554), Expect = e-172
Identities = 289/451 (64%), Positives = 365/451 (80%)
Query: 8 LFWYLDYNKDGTLDIFELQEGLEDVGAIQSLEEAKKIFTTGDVNKDGKLDFEEFMKYLKD 67
LF LD N+DG L + +L GL +G ++ E +KI GD + DG+LDFEEF+ YL+D
Sbjct: 53 LFQTLDVNRDGGLCVNDLAVGLRRLGLHRTEGELQKIVQAGDKDLDGQLDFEEFVHYLQD 112
Query: 68 HEKKMKLAFKSLDKNNDGKIEASEIVQSLQTLGLTISEQQAELILQSIDVDGTMTVDWNE 127
HEKK++L FKSLDK NDG+I+A EI+QSL+ LG+ ISEQQAE IL+S+D +GTMT+DWNE
Sbjct: 113 HEKKLRLVFKSLDKKNDGRIDAQEIMQSLRDLGVKISEQQAEKILKSMDKNGTMTIDWNE 172
Query: 128 WRDYFLFNPVTDIEEIIRFWKHSTGIDIGDSLTIPDEFTEDEKKSGQWWRQLLAGGIAGA 187
WRDY L +PV +I EII +WKHST D+G++LT+PDEFT +E+++G WWR L+AGG AGA
Sbjct: 173 WRDYHLLHPVENIPEIILYWKHSTIFDVGENLTVPDEFTVEERQTGMWWRHLVAGGGAGA 232
Query: 188 VSRTSTAPLDRLKIMMQVHGSKSDKMNIFGGFRQMVKEGGIRSLWRGNGTNVIKIAPETA 247
VSRT TAPLDRLK++MQVH S+S+ M I GGF QM++EGG RSLWRGNG NV+KIAPE+A
Sbjct: 233 VSRTCTAPLDRLKVLMQVHASRSNNMGIVGGFTQMIREGGARSLWRGNGINVLKIAPESA 292
Query: 248 VKFWAYEQYKKLLTEEGQKIGTFERFISGSMAGATAQTFIYPMEVMKTRLAVGKTGQYSG 307
+KF AYEQ K+L+ + + + ER ++GS+AGA AQ+ IYPMEV+KTR+A+ KTGQYSG
Sbjct: 293 IKFMAYEQIKRLVGSDQETLRIHERLVAGSLAGAIAQSSIYPMEVLKTRMALRKTGQYSG 352
Query: 308 IYDCAKKILKHEGLGAFYKGYVPNLLGIIPYAGIDLAVYELLKSYWLDNFAKDSVNPGVM 367
+ DCA++IL EG+ AFYKGYVPN+LGIIPYAGIDLAVYE LK+ WL ++A +S +PGV
Sbjct: 353 MLDCARRILAREGVAAFYKGYVPNMLGIIPYAGIDLAVYETLKNAWLQHYAVNSADPGVF 412
Query: 368 VLLGCGALSSTCGQLASYPLALVRTRMQAQAMLEGSPQLNMVGLFRRIISKEGIPGLYRG 427
VLL CG +SSTCGQLASYPLALVRTRMQAQA +EG+P++ M LF+ I+ EG GLYRG
Sbjct: 413 VLLACGTMSSTCGQLASYPLALVRTRMQAQASIEGAPEVTMSSLFKHILRTEGAFGLYRG 472
Query: 428 ITPNFMKVLPAVGISYVVYENMKQTLGVTQK 458
+ PNFMKV+PAV ISYVVYEN+K TLGV +
Sbjct: 473 LAPNFMKVIPAVSISYVVYENLKITLGVQSR 503
Score = 92.8 bits (229), Expect = 6e-19
Identities = 86/388 (22%), Positives = 165/388 (42%), Gaps = 41/388 (10%)
Query: 67 DHEKKMKLAFKSLDKNNDGKIEASEIVQSLQTLGLTISEQQAELILQSIDVDGTMTVDWN 126
DH ++ F++LD N DG + +++ L+ LGL +E + + I+Q+ D D +D+
Sbjct: 45 DHRLRLWRLFQTLDVNRDGGLCVNDLAVGLRRLGLHRTEGELQKIVQAGDKDLDGQLDFE 104
Query: 127 EWRDYFLFNPVTDIEEIIRFWKHSTGIDIGDSLTIPDEFTEDEKKSGQWWRQLLAGGIAG 186
E+ Y + D E+ +R S D+K G+ Q + +
Sbjct: 105 EFVHY-----LQDHEKKLRLVFKSL----------------DKKNDGRIDAQEIMQSLRD 143
Query: 187 AVSRTSTAPLDRLKIMMQVHGSKSDKMNIFGGFRQMVKEGGIRSL---WRGNGTNVIKIA 243
+ S +++ M +G+ + N + + + I + W+ + + +
Sbjct: 144 LGVKISEQQAEKILKSMDKNGTMTIDWNEWRDYHLLHPVENIPEIILYWK--HSTIFDVG 201
Query: 244 PETAVKFWAYEQYKKLLTEEGQKIGTFERFISGSMAGATAQTFIYPMEVMKTRLAV-GKT 302
V + EE Q + ++G AGA ++T P++ +K + V
Sbjct: 202 ENLTVP-------DEFTVEERQTGMWWRHLVAGGGAGAVSRTCTAPLDRLKVLMQVHASR 254
Query: 303 GQYSGIYDCAKKILKHEGLGAFYKGYVPNLLGIIPYAGIDLAVYELLKSYWLDNFAKDSV 362
GI ++++ G + ++G N+L I P + I YE +K D
Sbjct: 255 SNNMGIVGGFTQMIREGGARSLWRGNGINVLKIAPESAIKFMAYEQIKRL----VGSDQE 310
Query: 363 NPGVMVLLGCGALSSTCGQLASYPLALVRTRMQAQAMLEGSPQLNMVGLFRRIISKEGIP 422
+ L G+L+ Q + YP+ +++TRM A+ + M+ RRI+++EG+
Sbjct: 311 TLRIHERLVAGSLAGAIAQSSIYPMEVLKTRM---ALRKTGQYSGMLDCARRILAREGVA 367
Query: 423 GLYRGITPNFMKVLPAVGISYVVYENMK 450
Y+G PN + ++P GI VYE +K
Sbjct: 368 AFYKGYVPNMLGIIPYAGIDLAVYETLK 395
>gi|56699403 solute carrier family 25, member 25 isoform b [Homo
sapiens]
Length = 503
Score = 603 bits (1554), Expect = e-172
Identities = 289/451 (64%), Positives = 365/451 (80%)
Query: 8 LFWYLDYNKDGTLDIFELQEGLEDVGAIQSLEEAKKIFTTGDVNKDGKLDFEEFMKYLKD 67
LF LD N+DG L + +L GL +G ++ E +KI GD + DG+LDFEEF+ YL+D
Sbjct: 53 LFQTLDVNRDGGLCVNDLAVGLRRLGLHRTEGELQKIVQAGDKDLDGQLDFEEFVHYLQD 112
Query: 68 HEKKMKLAFKSLDKNNDGKIEASEIVQSLQTLGLTISEQQAELILQSIDVDGTMTVDWNE 127
HEKK++L FKSLDK NDG+I+A EI+QSL+ LG+ ISEQQAE IL+S+D +GTMT+DWNE
Sbjct: 113 HEKKLRLVFKSLDKKNDGRIDAQEIMQSLRDLGVKISEQQAEKILKSMDKNGTMTIDWNE 172
Query: 128 WRDYFLFNPVTDIEEIIRFWKHSTGIDIGDSLTIPDEFTEDEKKSGQWWRQLLAGGIAGA 187
WRDY L +PV +I EII +WKHST D+G++LT+PDEFT +E+++G WWR L+AGG AGA
Sbjct: 173 WRDYHLLHPVENIPEIILYWKHSTIFDVGENLTVPDEFTVEERQTGMWWRHLVAGGGAGA 232
Query: 188 VSRTSTAPLDRLKIMMQVHGSKSDKMNIFGGFRQMVKEGGIRSLWRGNGTNVIKIAPETA 247
VSRT TAPLDRLK++MQVH S+S+ M I GGF QM++EGG RSLWRGNG NV+KIAPE+A
Sbjct: 233 VSRTCTAPLDRLKVLMQVHASRSNNMGIVGGFTQMIREGGARSLWRGNGINVLKIAPESA 292
Query: 248 VKFWAYEQYKKLLTEEGQKIGTFERFISGSMAGATAQTFIYPMEVMKTRLAVGKTGQYSG 307
+KF AYEQ K+L+ + + + ER ++GS+AGA AQ+ IYPMEV+KTR+A+ KTGQYSG
Sbjct: 293 IKFMAYEQIKRLVGSDQETLRIHERLVAGSLAGAIAQSSIYPMEVLKTRMALRKTGQYSG 352
Query: 308 IYDCAKKILKHEGLGAFYKGYVPNLLGIIPYAGIDLAVYELLKSYWLDNFAKDSVNPGVM 367
+ DCA++IL EG+ AFYKGYVPN+LGIIPYAGIDLAVYE LK+ WL ++A +S +PGV
Sbjct: 353 MLDCARRILAREGVAAFYKGYVPNMLGIIPYAGIDLAVYETLKNAWLQHYAVNSADPGVF 412
Query: 368 VLLGCGALSSTCGQLASYPLALVRTRMQAQAMLEGSPQLNMVGLFRRIISKEGIPGLYRG 427
VLL CG +SSTCGQLASYPLALVRTRMQAQA +EG+P++ M LF+ I+ EG GLYRG
Sbjct: 413 VLLACGTMSSTCGQLASYPLALVRTRMQAQASIEGAPEVTMSSLFKHILRTEGAFGLYRG 472
Query: 428 ITPNFMKVLPAVGISYVVYENMKQTLGVTQK 458
+ PNFMKV+PAV ISYVVYEN+K TLGV +
Sbjct: 473 LAPNFMKVIPAVSISYVVYENLKITLGVQSR 503
Score = 92.8 bits (229), Expect = 6e-19
Identities = 86/388 (22%), Positives = 165/388 (42%), Gaps = 41/388 (10%)
Query: 67 DHEKKMKLAFKSLDKNNDGKIEASEIVQSLQTLGLTISEQQAELILQSIDVDGTMTVDWN 126
DH ++ F++LD N DG + +++ L+ LGL +E + + I+Q+ D D +D+
Sbjct: 45 DHRLRLWRLFQTLDVNRDGGLCVNDLAVGLRRLGLHRTEGELQKIVQAGDKDLDGQLDFE 104
Query: 127 EWRDYFLFNPVTDIEEIIRFWKHSTGIDIGDSLTIPDEFTEDEKKSGQWWRQLLAGGIAG 186
E+ Y + D E+ +R S D+K G+ Q + +
Sbjct: 105 EFVHY-----LQDHEKKLRLVFKSL----------------DKKNDGRIDAQEIMQSLRD 143
Query: 187 AVSRTSTAPLDRLKIMMQVHGSKSDKMNIFGGFRQMVKEGGIRSL---WRGNGTNVIKIA 243
+ S +++ M +G+ + N + + + I + W+ + + +
Sbjct: 144 LGVKISEQQAEKILKSMDKNGTMTIDWNEWRDYHLLHPVENIPEIILYWK--HSTIFDVG 201
Query: 244 PETAVKFWAYEQYKKLLTEEGQKIGTFERFISGSMAGATAQTFIYPMEVMKTRLAV-GKT 302
V + EE Q + ++G AGA ++T P++ +K + V
Sbjct: 202 ENLTVP-------DEFTVEERQTGMWWRHLVAGGGAGAVSRTCTAPLDRLKVLMQVHASR 254
Query: 303 GQYSGIYDCAKKILKHEGLGAFYKGYVPNLLGIIPYAGIDLAVYELLKSYWLDNFAKDSV 362
GI ++++ G + ++G N+L I P + I YE +K D
Sbjct: 255 SNNMGIVGGFTQMIREGGARSLWRGNGINVLKIAPESAIKFMAYEQIKRL----VGSDQE 310
Query: 363 NPGVMVLLGCGALSSTCGQLASYPLALVRTRMQAQAMLEGSPQLNMVGLFRRIISKEGIP 422
+ L G+L+ Q + YP+ +++TRM A+ + M+ RRI+++EG+
Sbjct: 311 TLRIHERLVAGSLAGAIAQSSIYPMEVLKTRM---ALRKTGQYSGMLDCARRILAREGVA 367
Query: 423 GLYRGITPNFMKVLPAVGISYVVYENMK 450
Y+G PN + ++P GI VYE +K
Sbjct: 368 AFYKGYVPNMLGIIPYAGIDLAVYETLK 395
>gi|48476342 solute carrier family 25, member 23 [Homo sapiens]
Length = 468
Score = 594 bits (1531), Expect = e-170
Identities = 281/455 (61%), Positives = 365/455 (80%), Gaps = 1/455 (0%)
Query: 5 YGDLFWYLDYNKDGTLDIFELQEGLEDVGAIQSLEEAKK-IFTTGDVNKDGKLDFEEFMK 63
+G LF LD NKDG +D+ EL++GL +G A++ I + GD + DG LD EEF +
Sbjct: 14 WGRLFEELDSNKDGRVDVHELRQGLARLGGGNPDPGAQQGISSEGDADPDGGLDLEEFSR 73
Query: 64 YLKDHEKKMKLAFKSLDKNNDGKIEASEIVQSLQTLGLTISEQQAELILQSIDVDGTMTV 123
YL++ E+++ L F SLD+N DG I+ SEI QS + LG++IS +QAE IL S+D DGTMT+
Sbjct: 74 YLQEREQRLLLMFHSLDRNQDGHIDVSEIQQSFRALGISISLEQAEKILHSMDRDGTMTI 133
Query: 124 DWNEWRDYFLFNPVTDIEEIIRFWKHSTGIDIGDSLTIPDEFTEDEKKSGQWWRQLLAGG 183
DW EWRD+FL + + ++E+++ FWKHST +DIG+ LT+PDEF++ EK +G WW+QL+AG
Sbjct: 134 DWQEWRDHFLLHSLENVEDVLYFWKHSTVLDIGECLTVPDEFSKQEKLTGMWWKQLVAGA 193
Query: 184 IAGAVSRTSTAPLDRLKIMMQVHGSKSDKMNIFGGFRQMVKEGGIRSLWRGNGTNVIKIA 243
+AGAVSRT TAPLDRLK+ MQVH SK++++NI GG R MV EGGIRSLWRGNG NV+KIA
Sbjct: 194 VAGAVSRTGTAPLDRLKVFMQVHASKTNRLNILGGLRSMVLEGGIRSLWRGNGINVLKIA 253
Query: 244 PETAVKFWAYEQYKKLLTEEGQKIGTFERFISGSMAGATAQTFIYPMEVMKTRLAVGKTG 303
PE+A+KF AYEQ K+ + + + + ERF++GS+AGATAQT IYPMEV+KTRL + +TG
Sbjct: 254 PESAIKFMAYEQIKRAILGQQETLHVQERFVAGSLAGATAQTIIYPMEVLKTRLTLRRTG 313
Query: 304 QYSGIYDCAKKILKHEGLGAFYKGYVPNLLGIIPYAGIDLAVYELLKSYWLDNFAKDSVN 363
QY G+ DCA++IL+ EG AFY+GY+PN+LGIIPYAGIDLAVYE LK++WL ++ DS +
Sbjct: 314 QYKGLLDCARRILEREGPRAFYRGYLPNVLGIIPYAGIDLAVYETLKNWWLQQYSHDSAD 373
Query: 364 PGVMVLLGCGALSSTCGQLASYPLALVRTRMQAQAMLEGSPQLNMVGLFRRIISKEGIPG 423
PG++VLL CG +SSTCGQ+ASYPLALVRTRMQAQA +EG PQL+M+GL R I+S+EG+ G
Sbjct: 374 PGILVLLACGTISSTCGQIASYPLALVRTRMQAQASIEGGPQLSMLGLLRHILSQEGMRG 433
Query: 424 LYRGITPNFMKVLPAVGISYVVYENMKQTLGVTQK 458
LYRGI PNFMKV+PAV ISYVVYENMKQ LGVT +
Sbjct: 434 LYRGIAPNFMKVIPAVSISYVVYENMKQALGVTSR 468
>gi|56699407 solute carrier family 25, member 25 isoform c [Homo
sapiens]
Length = 489
Score = 585 bits (1509), Expect = e-167
Identities = 277/417 (66%), Positives = 346/417 (82%)
Query: 42 KKIFTTGDVNKDGKLDFEEFMKYLKDHEKKMKLAFKSLDKNNDGKIEASEIVQSLQTLGL 101
KKI GD + DG+LDFEEF+ YL+DHEKK++L FKSLDK NDG+I+A EI+QSL+ LG+
Sbjct: 73 KKIVQAGDKDLDGQLDFEEFVHYLQDHEKKLRLVFKSLDKKNDGRIDAQEIMQSLRDLGV 132
Query: 102 TISEQQAELILQSIDVDGTMTVDWNEWRDYFLFNPVTDIEEIIRFWKHSTGIDIGDSLTI 161
ISEQQAE IL+S+D +GTMT+DWNEWRDY L +PV +I EII +WKHST D+G++LT+
Sbjct: 133 KISEQQAEKILKSMDKNGTMTIDWNEWRDYHLLHPVENIPEIILYWKHSTIFDVGENLTV 192
Query: 162 PDEFTEDEKKSGQWWRQLLAGGIAGAVSRTSTAPLDRLKIMMQVHGSKSDKMNIFGGFRQ 221
PDEFT +E+++G WWR L+AGG AGAVSRT TAPLDRLK++MQVH S+S+ M I GGF Q
Sbjct: 193 PDEFTVEERQTGMWWRHLVAGGGAGAVSRTCTAPLDRLKVLMQVHASRSNNMGIVGGFTQ 252
Query: 222 MVKEGGIRSLWRGNGTNVIKIAPETAVKFWAYEQYKKLLTEEGQKIGTFERFISGSMAGA 281
M++EGG RSLWRGNG NV+KIAPE+A+KF AYEQ K+L+ + + + ER ++GS+AGA
Sbjct: 253 MIREGGARSLWRGNGINVLKIAPESAIKFMAYEQIKRLVGSDQETLRIHERLVAGSLAGA 312
Query: 282 TAQTFIYPMEVMKTRLAVGKTGQYSGIYDCAKKILKHEGLGAFYKGYVPNLLGIIPYAGI 341
AQ+ IYPMEV+KTR+A+ KTGQYSG+ DCA++IL EG+ AFYKGYVPN+LGIIPYAGI
Sbjct: 313 IAQSSIYPMEVLKTRMALRKTGQYSGMLDCARRILAREGVAAFYKGYVPNMLGIIPYAGI 372
Query: 342 DLAVYELLKSYWLDNFAKDSVNPGVMVLLGCGALSSTCGQLASYPLALVRTRMQAQAMLE 401
DLAVYE LK+ WL ++A +S +PGV VLL CG +SSTCGQLASYPLALVRTRMQAQA +E
Sbjct: 373 DLAVYETLKNAWLQHYAVNSADPGVFVLLACGTMSSTCGQLASYPLALVRTRMQAQASIE 432
Query: 402 GSPQLNMVGLFRRIISKEGIPGLYRGITPNFMKVLPAVGISYVVYENMKQTLGVTQK 458
G+P++ M LF+ I+ EG GLYRG+ PNFMKV+PAV ISYVVYEN+K TLGV +
Sbjct: 433 GAPEVTMSSLFKHILRTEGAFGLYRGLAPNFMKVIPAVSISYVVYENLKITLGVQSR 489
>gi|239755176 PREDICTED: similar to solute carrier family 25, member
25 isoform 2 [Homo sapiens]
Length = 469
Score = 584 bits (1505), Expect = e-167
Identities = 276/417 (66%), Positives = 346/417 (82%)
Query: 42 KKIFTTGDVNKDGKLDFEEFMKYLKDHEKKMKLAFKSLDKNNDGKIEASEIVQSLQTLGL 101
+KI GD + DG+LDFEEF+ YL+DHEKK++L FKSLDK NDG+I+A EI+QSL+ LG+
Sbjct: 53 QKIVQAGDKDLDGQLDFEEFVHYLQDHEKKLRLVFKSLDKKNDGRIDAQEIMQSLRDLGV 112
Query: 102 TISEQQAELILQSIDVDGTMTVDWNEWRDYFLFNPVTDIEEIIRFWKHSTGIDIGDSLTI 161
ISEQQAE IL+S+D +GTMT+DWNEWRDY L +PV +I EII +WKHST D+G++LT+
Sbjct: 113 KISEQQAEKILKSMDKNGTMTIDWNEWRDYHLLHPVENIPEIILYWKHSTIFDVGENLTV 172
Query: 162 PDEFTEDEKKSGQWWRQLLAGGIAGAVSRTSTAPLDRLKIMMQVHGSKSDKMNIFGGFRQ 221
PDEFT +E+++G WWR L+AGG AGAVSRT TAPLDRLK++MQVH S+S+ M I GGF Q
Sbjct: 173 PDEFTVEERQTGMWWRHLVAGGGAGAVSRTCTAPLDRLKVLMQVHASRSNNMGIVGGFTQ 232
Query: 222 MVKEGGIRSLWRGNGTNVIKIAPETAVKFWAYEQYKKLLTEEGQKIGTFERFISGSMAGA 281
M++EGG RSLWRGNG NV+KIAPE+A+KF AYEQ K+L+ + + + ER ++GS+AGA
Sbjct: 233 MIREGGARSLWRGNGINVLKIAPESAIKFMAYEQIKRLVGSDQETLRIHERLVAGSLAGA 292
Query: 282 TAQTFIYPMEVMKTRLAVGKTGQYSGIYDCAKKILKHEGLGAFYKGYVPNLLGIIPYAGI 341
AQ+ IYPMEV+KTR+A+ KTGQYSG+ DCA++IL EG+ AFYKGYVPN+LGIIPYAGI
Sbjct: 293 IAQSSIYPMEVLKTRMALRKTGQYSGMLDCARRILAREGVAAFYKGYVPNMLGIIPYAGI 352
Query: 342 DLAVYELLKSYWLDNFAKDSVNPGVMVLLGCGALSSTCGQLASYPLALVRTRMQAQAMLE 401
DLAVYE LK+ WL ++A +S +PGV VLL CG +SSTCGQLASYPLALVRTRMQAQA +E
Sbjct: 353 DLAVYETLKNAWLQHYAVNSADPGVFVLLACGTMSSTCGQLASYPLALVRTRMQAQASIE 412
Query: 402 GSPQLNMVGLFRRIISKEGIPGLYRGITPNFMKVLPAVGISYVVYENMKQTLGVTQK 458
G+P++ M LF+ I+ EG GLYRG+ PNFMKV+PAV ISYVVYEN+K TLGV +
Sbjct: 413 GAPEVTMSSLFKHILRTEGAFGLYRGLAPNFMKVIPAVSISYVVYENLKITLGVQSR 469
>gi|56699401 solute carrier family 25, member 25 isoform a [Homo
sapiens]
Length = 469
Score = 584 bits (1505), Expect = e-167
Identities = 276/417 (66%), Positives = 346/417 (82%)
Query: 42 KKIFTTGDVNKDGKLDFEEFMKYLKDHEKKMKLAFKSLDKNNDGKIEASEIVQSLQTLGL 101
+KI GD + DG+LDFEEF+ YL+DHEKK++L FKSLDK NDG+I+A EI+QSL+ LG+
Sbjct: 53 QKIVQAGDKDLDGQLDFEEFVHYLQDHEKKLRLVFKSLDKKNDGRIDAQEIMQSLRDLGV 112
Query: 102 TISEQQAELILQSIDVDGTMTVDWNEWRDYFLFNPVTDIEEIIRFWKHSTGIDIGDSLTI 161
ISEQQAE IL+S+D +GTMT+DWNEWRDY L +PV +I EII +WKHST D+G++LT+
Sbjct: 113 KISEQQAEKILKSMDKNGTMTIDWNEWRDYHLLHPVENIPEIILYWKHSTIFDVGENLTV 172
Query: 162 PDEFTEDEKKSGQWWRQLLAGGIAGAVSRTSTAPLDRLKIMMQVHGSKSDKMNIFGGFRQ 221
PDEFT +E+++G WWR L+AGG AGAVSRT TAPLDRLK++MQVH S+S+ M I GGF Q
Sbjct: 173 PDEFTVEERQTGMWWRHLVAGGGAGAVSRTCTAPLDRLKVLMQVHASRSNNMGIVGGFTQ 232
Query: 222 MVKEGGIRSLWRGNGTNVIKIAPETAVKFWAYEQYKKLLTEEGQKIGTFERFISGSMAGA 281
M++EGG RSLWRGNG NV+KIAPE+A+KF AYEQ K+L+ + + + ER ++GS+AGA
Sbjct: 233 MIREGGARSLWRGNGINVLKIAPESAIKFMAYEQIKRLVGSDQETLRIHERLVAGSLAGA 292
Query: 282 TAQTFIYPMEVMKTRLAVGKTGQYSGIYDCAKKILKHEGLGAFYKGYVPNLLGIIPYAGI 341
AQ+ IYPMEV+KTR+A+ KTGQYSG+ DCA++IL EG+ AFYKGYVPN+LGIIPYAGI
Sbjct: 293 IAQSSIYPMEVLKTRMALRKTGQYSGMLDCARRILAREGVAAFYKGYVPNMLGIIPYAGI 352
Query: 342 DLAVYELLKSYWLDNFAKDSVNPGVMVLLGCGALSSTCGQLASYPLALVRTRMQAQAMLE 401
DLAVYE LK+ WL ++A +S +PGV VLL CG +SSTCGQLASYPLALVRTRMQAQA +E
Sbjct: 353 DLAVYETLKNAWLQHYAVNSADPGVFVLLACGTMSSTCGQLASYPLALVRTRMQAQASIE 412
Query: 402 GSPQLNMVGLFRRIISKEGIPGLYRGITPNFMKVLPAVGISYVVYENMKQTLGVTQK 458
G+P++ M LF+ I+ EG GLYRG+ PNFMKV+PAV ISYVVYEN+K TLGV +
Sbjct: 413 GAPEVTMSSLFKHILRTEGAFGLYRGLAPNFMKVIPAVSISYVVYENLKITLGVQSR 469
>gi|56699405 solute carrier family 25, member 25 isoform d [Homo
sapiens]
Length = 366
Score = 514 bits (1325), Expect = e-146
Identities = 243/366 (66%), Positives = 304/366 (83%)
Query: 93 VQSLQTLGLTISEQQAELILQSIDVDGTMTVDWNEWRDYFLFNPVTDIEEIIRFWKHSTG 152
+QSL+ LG+ ISEQQAE IL+S+D +GTMT+DWNEWRDY L +PV +I EII +WKHST
Sbjct: 1 MQSLRDLGVKISEQQAEKILKSMDKNGTMTIDWNEWRDYHLLHPVENIPEIILYWKHSTI 60
Query: 153 IDIGDSLTIPDEFTEDEKKSGQWWRQLLAGGIAGAVSRTSTAPLDRLKIMMQVHGSKSDK 212
D+G++LT+PDEFT +E+++G WWR L+AGG AGAVSRT TAPLDRLK++MQVH S+S+
Sbjct: 61 FDVGENLTVPDEFTVEERQTGMWWRHLVAGGGAGAVSRTCTAPLDRLKVLMQVHASRSNN 120
Query: 213 MNIFGGFRQMVKEGGIRSLWRGNGTNVIKIAPETAVKFWAYEQYKKLLTEEGQKIGTFER 272
M I GGF QM++EGG RSLWRGNG NV+KIAPE+A+KF AYEQ K+L+ + + + ER
Sbjct: 121 MGIVGGFTQMIREGGARSLWRGNGINVLKIAPESAIKFMAYEQIKRLVGSDQETLRIHER 180
Query: 273 FISGSMAGATAQTFIYPMEVMKTRLAVGKTGQYSGIYDCAKKILKHEGLGAFYKGYVPNL 332
++GS+AGA AQ+ IYPMEV+KTR+A+ KTGQYSG+ DCA++IL EG+ AFYKGYVPN+
Sbjct: 181 LVAGSLAGAIAQSSIYPMEVLKTRMALRKTGQYSGMLDCARRILAREGVAAFYKGYVPNM 240
Query: 333 LGIIPYAGIDLAVYELLKSYWLDNFAKDSVNPGVMVLLGCGALSSTCGQLASYPLALVRT 392
LGIIPYAGIDLAVYE LK+ WL ++A +S +PGV VLL CG +SSTCGQLASYPLALVRT
Sbjct: 241 LGIIPYAGIDLAVYETLKNAWLQHYAVNSADPGVFVLLACGTMSSTCGQLASYPLALVRT 300
Query: 393 RMQAQAMLEGSPQLNMVGLFRRIISKEGIPGLYRGITPNFMKVLPAVGISYVVYENMKQT 452
RMQAQA +EG+P++ M LF+ I+ EG GLYRG+ PNFMKV+PAV ISYVVYEN+K T
Sbjct: 301 RMQAQASIEGAPEVTMSSLFKHILRTEGAFGLYRGLAPNFMKVIPAVSISYVVYENLKIT 360
Query: 453 LGVTQK 458
LGV +
Sbjct: 361 LGVQSR 366
>gi|149274607 solute carrier family 25, member 41 [Homo sapiens]
Length = 370
Score = 320 bits (819), Expect = 2e-87
Identities = 166/303 (54%), Positives = 218/303 (71%), Gaps = 3/303 (0%)
Query: 153 IDIGDSLTIPDEFTEDEKKSGQWWRQLLAGGIAGAVSRTSTAPLDRLKIMMQVHGSKSDK 212
+D G+ L +P E E + K W + LL+G +AGAVSRT TAPLDR K+ MQV+ SK++
Sbjct: 71 LDTGEQLMVPVEVLEVDNKEALW-KFLLSGAMAGAVSRTGTAPLDRAKVYMQVYSSKTNF 129
Query: 213 MNIFGGFRQMVKEGGIRSLWRGNGTNVIKIAPETAVKFWAYEQYKKLLTEEGQKIGTFER 272
N+ GG + MV+EGG RSLWRGNG NV+KIAPE A+KF +EQ K ER
Sbjct: 130 TNLLGGLQSMVQEGGFRSLWRGNGINVLKIAPEYAIKFSVFEQCKNYFCGIQGSPPFQER 189
Query: 273 FISGSMAGATAQTFIYPMEVMKTRLAVGKTGQYSGIYDCAKKILKHEGLGAFYKGYVPNL 332
++GS+A A +QT I PMEV+KTRL + +TGQY G+ DCA++IL+ EG A Y+GY+PN+
Sbjct: 190 LLAGSLAVAISQTLINPMEVLKTRLTLRRTGQYKGLLDCARQILQREGTRALYRGYLPNM 249
Query: 333 LGIIPYAGIDLAVYELLKSYWLDNFAKDSVNPGVMVLLGCGALSSTCGQLASYPLALVRT 392
LGIIPYA DLAVYE+L+ +W+ + +D +P +V L LS+TCGQ+ASYPL LVRT
Sbjct: 250 LGIIPYACTDLAVYEMLQCFWVKS-GRDMGDPSGLVSLSSVTLSTTCGQMASYPLTLVRT 308
Query: 393 RMQAQAMLEGSPQLNMVGLFRRIISKEGIPGLYRGITPNFMKVLPAVGISYVVYENMKQT 452
RMQAQ +EGS M G+ +RI++++G GLYRG+TP +KVLPA GISYVVYE MK+T
Sbjct: 309 RMQAQDTVEGS-NPTMRGVLQRILAQQGWLGLYRGMTPTLLKVLPAGGISYVVYEAMKKT 367
Query: 453 LGV 455
LG+
Sbjct: 368 LGI 370
>gi|27544933 solute carrier family 25, member 16 [Homo sapiens]
Length = 332
Score = 182 bits (463), Expect = 4e-46
Identities = 107/292 (36%), Positives = 161/292 (55%), Gaps = 15/292 (5%)
Query: 175 WWRQLLAGGIAGAVSRTSTAPLDRLKIMMQVHGSKSDKMNIFGGFRQMVKEGGIRSLWRG 234
W R LAGGIAG ++T+ APLDR+K+++Q H + +F R + ++ G L++G
Sbjct: 36 WLRSFLAGGIAGCCAKTTVAPLDRVKVLLQAHNHHYKHLGVFSALRAVPQKEGFLGLYKG 95
Query: 235 NGTNVIKIAPETAVKFWAYEQYKKLLTEEGQKIGTFERFISGSMAGATAQTFIYPMEVMK 294
NG +I+I P A++F A+E YK L+T + G R ++GSMAG TA YP+++++
Sbjct: 96 NGAMMIRIFPYGAIQFMAFEHYKTLITTKLGISGHVHRLMAGSMAGMTAVICTYPLDMVR 155
Query: 295 TRLAVGKTGQ--YSGIYDCAKKI-LKHEGLGAFYKGYVPNLLGIIPYAGIDLAVYELLKS 351
RLA G+ Y+GI K I K G FY+G +P +LG+ PYAG+ + LKS
Sbjct: 156 VRLAFQVKGEHSYTGIIHAFKTIYAKEGGFFGFYRGLMPTILGMAPYAGVSFFTFGTLKS 215
Query: 352 YWLDNF-----AKDSVNPGVMVL-----LGCGALSSTCGQLASYPLALVRTRMQAQAML- 400
L + S NP V+VL L CG ++ Q SYP + R RMQ +L
Sbjct: 216 VGLSHAPTLLGRPSSDNPNVLVLKTHVNLLCGGVAGAIAQTISYPFDVTRRRMQLGTVLP 275
Query: 401 EGSPQLNMVGLFRRIISKEGI-PGLYRGITPNFMKVLPAVGISYVVYENMKQ 451
E L M + + GI GLYRG++ N+++ +P+ +++ YE MKQ
Sbjct: 276 EFEKCLTMRDTMKYVYGHHGIRKGLYRGLSLNYIRCIPSQAVAFTTYELMKQ 327
Score = 68.6 bits (166), Expect = 1e-11
Identities = 55/198 (27%), Positives = 89/198 (44%), Gaps = 23/198 (11%)
Query: 178 QLLAGGIAGAVSRTSTAPLD--RLKIMMQVHGSKSDKMNIFGGFRQM-VKEGGIRSLWRG 234
+L+AG +AG + T PLD R+++ QV G S I F+ + KEGG +RG
Sbjct: 133 RLMAGSMAGMTAVICTYPLDMVRVRLAFQVKGEHS-YTGIIHAFKTIYAKEGGFFGFYRG 191
Query: 235 NGTNVIKIAPETAVKFWAYEQYKKL-LTEEGQKIG-------------TFERFISGSMAG 280
++ +AP V F+ + K + L+ +G T + G +AG
Sbjct: 192 LMPTILGMAPYAGVSFFTFGTLKSVGLSHAPTLLGRPSSDNPNVLVLKTHVNLLCGGVAG 251
Query: 281 ATAQTFIYPMEVMKTRLAVGKT----GQYSGIYDCAKKILKHEGLG-AFYKGYVPNLLGI 335
A AQT YP +V + R+ +G + + D K + H G+ Y+G N +
Sbjct: 252 AIAQTISYPFDVTRRRMQLGTVLPEFEKCLTMRDTMKYVYGHHGIRKGLYRGLSLNYIRC 311
Query: 336 IPYAGIDLAVYELLKSYW 353
IP + YEL+K ++
Sbjct: 312 IPSQAVAFTTYELMKQFF 329
>gi|60460887 solute carrier family 25, member 42 [Homo sapiens]
Length = 318
Score = 181 bits (459), Expect = 1e-45
Identities = 100/277 (36%), Positives = 160/277 (57%), Gaps = 8/277 (2%)
Query: 179 LLAGGIAGAVSRTSTAPLDRLKIMMQVHGSKSDKMNIFGGFRQMVKEGGIRSLWRGNGTN 238
LL G +AGA+++T+ APLDR KI+ QV + F G SLWRGN
Sbjct: 37 LLPGALAGALAKTAVAPLDRTKIIFQVSSKRFSAKEAFRVLYYTYLNEGFLSLWRGNSAT 96
Query: 239 VIKIAPETAVKFWAYEQYKKLLTE----EGQKIGTFERFISGSMAGATAQTFIYPMEVMK 294
++++ P A++F A+E+YK++L G+ + + R +G++AG TA + YP+++++
Sbjct: 97 MVRVVPYAAIQFSAHEEYKRILGSYYGFRGEALPPWPRLFAGALAGTTAASLTYPLDLVR 156
Query: 295 TRLAVGKTGQYSGIYDCAKKILKHEGLGAFYKGYVPNLLGIIPYAGIDLAVYELLKSYWL 354
R+AV YS I+ +I + EGL Y G++P +LG+IPYAG+ YE LKS
Sbjct: 157 ARMAVTPKEMYSNIFHVFIRISREEGLKTLYHGFMPTVLGVIPYAGLSFFTYETLKSLHR 216
Query: 355 DNFAKDSVNPGVMVLLGCGALSSTCGQLASYPLALVRTRMQAQAMLEGSPQLNMVGLFRR 414
+ + P ++ GA + GQ ASYPL +VR RMQ A + G P+ ++ R
Sbjct: 217 EYSGRRQPYPFERMIF--GACAGLIGQSASYPLDVVRRRMQT-AGVTGYPRASIARTLRT 273
Query: 415 IISKEG-IPGLYRGITPNFMKVLPAVGISYVVYENMK 450
I+ +EG + GLY+G++ N++K AVGIS+ ++ M+
Sbjct: 274 IVREEGAVRGLYKGLSMNWVKGPIAVGISFTTFDLMQ 310
Score = 75.5 bits (184), Expect = 9e-14
Identities = 55/180 (30%), Positives = 91/180 (50%), Gaps = 6/180 (3%)
Query: 176 WRQLLAGGIAGAVSRTSTAPLDRLKIMMQVHGSKSDKMNIFGGFRQMVKEGGIRSLWRGN 235
W +L AG +AG + + T PLD ++ M V K NIF F ++ +E G+++L+ G
Sbjct: 132 WPRLFAGALAGTTAASLTYPLDLVRARMAV-TPKEMYSNIFHVFIRISREEGLKTLYHGF 190
Query: 236 GTNVIKIAPETAVKFWAYEQYKKLLTEEG--QKIGTFERFISGSMAGATAQTFIYPMEVM 293
V+ + P + F+ YE K L E ++ FER I G+ AG Q+ YP++V+
Sbjct: 191 MPTVLGVIPYAGLSFFTYETLKSLHREYSGRRQPYPFERMIFGACAGLIGQSASYPLDVV 250
Query: 294 KTRL-AVGKTG-QYSGIYDCAKKILKHEG-LGAFYKGYVPNLLGIIPYAGIDLAVYELLK 350
+ R+ G TG + I + I++ EG + YKG N + GI ++L++
Sbjct: 251 RRRMQTAGVTGYPRASIARTLRTIVREEGAVRGLYKGLSMNWVKGPIAVGISFTTFDLMQ 310
Score = 29.6 bits (65), Expect = 6.0
Identities = 20/82 (24%), Positives = 36/82 (43%), Gaps = 2/82 (2%)
Query: 373 GALSSTCGQLASYPLALVRTRMQAQAMLEGSPQLNMVGLFRRIISKEGIPGLYRGITPNF 432
GAL+ + A PL + Q + + + V + + EG L+RG +
Sbjct: 40 GALAGALAKTAVAPLDRTKIIFQVSSKRFSAKEAFRVLYYTYL--NEGFLSLWRGNSATM 97
Query: 433 MKVLPAVGISYVVYENMKQTLG 454
++V+P I + +E K+ LG
Sbjct: 98 VRVVPYAAIQFSAHEEYKRILG 119
>gi|156071462 solute carrier family 25, member A6 [Homo sapiens]
Length = 298
Score = 137 bits (345), Expect = 2e-32
Identities = 94/295 (31%), Positives = 155/295 (52%), Gaps = 24/295 (8%)
Query: 177 RQLLAGGIAGAVSRTSTAPLDRLKIMMQV-HGSK---SDKM--NIFGGFRQMVKEGGIRS 230
+ LAGGIA A+S+T+ AP++R+K+++QV H SK +DK I ++ KE G+ S
Sbjct: 10 KDFLAGGIAAAISKTAVAPIERVKLLLQVQHASKQIAADKQYKGIVDCIVRIPKEQGVLS 69
Query: 231 LWRGNGTNVIKIAPETAVKFWAYEQYKKLLTEEGQKIGTFERFISGSM-----AGATAQT 285
WRGN NVI+ P A+ F ++YK++ K F R+ +G++ AGAT+
Sbjct: 70 FWRGNLANVIRYFPTQALNFAFKDKYKQIFLGGVDKHTQFWRYFAGNLASGGAAGATSLC 129
Query: 286 FIYPMEVMKTRLA--VGKTG---QYSGIYDCAKKILKHEGLGAFYKGYVPNLLGIIPYAG 340
F+YP++ +TRLA VGK+G ++ G+ DC KI K +G+ Y+G+ ++ GII Y
Sbjct: 130 FVYPLDFARTRLAADVGKSGTEREFRGLGDCLVKITKSDGIRGLYQGFSVSVQGIIIYRA 189
Query: 341 IDLAVYELLKSYWLDNFAKDSVNPGVMVLLGCGALSSTCGQLASYPLALVRTRMQAQAML 400
VY+ K D N ++V + + SYP VR RM Q+
Sbjct: 190 AYFGVYDTAK-----GMLPDPKNTHIVVSWMIAQTVTAVAGVVSYPFDTVRRRMMMQSGR 244
Query: 401 EGSPQL--NMVGLFRRIISKEGIPGLYRGITPNFMKVLPAVGISYVVYENMKQTL 453
+G+ + V +R+I EG ++G N ++ + + V+Y+ +K+ +
Sbjct: 245 KGADIMYTGTVDCWRKIFRDEGGKAFFKGAWSNVLRGMGGAFV-LVLYDELKKVI 298
>gi|13775208 solute carrier family 25 (mitochondrial carrier;
adenine nucleotide translocator), member 31 [Homo
sapiens]
Length = 315
Score = 132 bits (332), Expect = 7e-31
Identities = 94/294 (31%), Positives = 145/294 (49%), Gaps = 28/294 (9%)
Query: 177 RQLLAGGIAGAVSRTSTAPLDRLKIMMQVHGSKSDKMNIFGGFRQMV-------KEGGIR 229
+ LLAGG+A AVS+T+ AP++R+K+++QV S S +++ ++ MV +E G
Sbjct: 22 KDLLAGGVAAAVSKTAVAPIERVKLLLQVQAS-SKQISPEARYKGMVDCLVRIPREQGFF 80
Query: 230 SLWRGNGTNVIKIAPETAVKFWAYEQYKKLLTEEGQKIGTFERFI-----SGSMAGATAQ 284
S WRGN NVI+ P A+ F ++YK+L K F R+ SG AGAT+
Sbjct: 81 SFWRGNLANVIRYFPTQALNFAFKDKYKQLFMSGVNKEKQFWRWFLANLASGGAAGATSL 140
Query: 285 TFIYPMEVMKTRLAVG-----KTGQYSGIYDCAKKILKHEGLGAFYKGYVPNLLGIIPYA 339
+YP++ +TRL V + Q+ G+ DC KI K +G+ Y+G+ ++ GII Y
Sbjct: 141 CVVYPLDFARTRLGVDIGKGPEERQFKGLGDCIMKIAKSDGIAGLYQGFGVSVQGIIVYR 200
Query: 340 GIDLAVYELLKSYWLDNFAKDSVNPGVMVLLGCGALSSTCGQLASYPLALVRTRMQAQAM 399
Y+ +K K P +V + +TC + SYP VR RM Q+
Sbjct: 201 ASYFGAYDTVKGL----LPKPKKTP-FLVSFFIAQVVTTCSGILSYPFDTVRRRMMMQSG 255
Query: 400 LEGSPQLNMVGLFRRIISKEGIPGLYRGITPNFMKVLPAVG--ISYVVYENMKQ 451
+ F +I EGI +RG F VL G + V+Y+ +K+
Sbjct: 256 EAKRQYKGTLDCFVKIYQHEGISSFFRGA---FSNVLRGTGGALVLVLYDKIKE 306
Score = 57.8 bits (138), Expect = 2e-08
Identities = 44/196 (22%), Positives = 86/196 (43%), Gaps = 12/196 (6%)
Query: 274 ISGSMAGATAQTFIYPMEVMKTRLAVGKTGQ-------YSGIYDCAKKILKHEGLGAFYK 326
++G +A A ++T + P+E +K L V + + Y G+ DC +I + +G +F++
Sbjct: 25 LAGGVAAAVSKTAVAPIERVKLLLQVQASSKQISPEARYKGMVDCLVRIPREQGFFSFWR 84
Query: 327 GYVPNLLGIIPYAGIDLAVYELLKSYWLDNFAKDSVN-PGVMVLLGCGALSSTCGQLASY 385
G + N++ P ++ A + K ++ K+ + L G + Y
Sbjct: 85 GNLANVIRYFPTQALNFAFKDKYKQLFMSGVNKEKQFWRWFLANLASGGAAGATSLCVVY 144
Query: 386 PLALVRTRMQAQAMLEGSPQLNMVGL---FRRIISKEGIPGLYRGITPNFMKVLPAVGIS 442
PL RTR+ + +G + GL +I +GI GLY+G + ++
Sbjct: 145 PLDFARTRLGVD-IGKGPEERQFKGLGDCIMKIAKSDGIAGLYQGFGVSVQGIIVYRASY 203
Query: 443 YVVYENMKQTLGVTQK 458
+ Y+ +K L +K
Sbjct: 204 FGAYDTVKGLLPKPKK 219
>gi|55749577 solute carrier family 25 (mitochondrial carrier;
adenine nucleotide translocator), member 4 [Homo
sapiens]
Length = 298
Score = 131 bits (329), Expect = 1e-30
Identities = 93/293 (31%), Positives = 147/293 (50%), Gaps = 24/293 (8%)
Query: 177 RQLLAGGIAGAVSRTSTAPLDRLKIMMQV-HGSKS-----DKMNIFGGFRQMVKEGGIRS 230
+ LAGG+A AVS+T+ AP++R+K+++QV H SK I ++ KE G S
Sbjct: 10 KDFLAGGVAAAVSKTAVAPIERVKLLLQVQHASKQISAEKQYKGIIDCVVRIPKEQGFLS 69
Query: 231 LWRGNGTNVIKIAPETAVKFWAYEQYKKLLTEEGQKIGTFERFISGSM-----AGATAQT 285
WRGN NVI+ P A+ F ++YK+L + F R+ +G++ AGAT+
Sbjct: 70 FWRGNLANVIRYFPTQALNFAFKDKYKQLFLGGVDRHKQFWRYFAGNLASGGAAGATSLC 129
Query: 286 FIYPMEVMKTRLA--VGKTG---QYSGIYDCAKKILKHEGLGAFYKGYVPNLLGIIPYAG 340
F+YP++ +TRLA VGK ++ G+ DC KI K +GL Y+G+ ++ GII Y
Sbjct: 130 FVYPLDFARTRLAADVGKGAAQREFHGLGDCIIKIFKSDGLRGLYQGFNVSVQGIIIYRA 189
Query: 341 IDLAVYELLKSYWLDNFAKDSVNPGVMVLLGCGALSSTCGQLASYPLALVRTRMQAQAML 400
VY+ K D N + V + L SYP VR RM Q+
Sbjct: 190 AYFGVYDTAK-----GMLPDPKNVHIFVSWMIAQSVTAVAGLVSYPFDTVRRRMMMQSGR 244
Query: 401 EGSPQL--NMVGLFRRIISKEGIPGLYRGITPNFMKVLPAVGISYVVYENMKQ 451
+G+ + V +R+I EG ++G N ++ + + V+Y+ +K+
Sbjct: 245 KGADIMYTGTVDCWRKIAKDEGAKAFFKGAWSNVLRGMGGAFV-LVLYDEIKK 296
Score = 64.3 bits (155), Expect = 2e-10
Identities = 51/195 (26%), Positives = 86/195 (44%), Gaps = 18/195 (9%)
Query: 273 FISGSMAGATAQTFIYPMEVMKTRLAVGKTG-------QYSGIYDCAKKILKHEGLGAFY 325
F++G +A A ++T + P+E +K L V QY GI DC +I K +G +F+
Sbjct: 12 FLAGGVAAAVSKTAVAPIERVKLLLQVQHASKQISAEKQYKGIIDCVVRIPKEQGFLSFW 71
Query: 326 KGYVPNLLGIIPYAGIDLAVYELLKSYWLDNFAKDS----VNPGVMVLLGCGALSSTCGQ 381
+G + N++ P ++ A + K +L + G + G +S C
Sbjct: 72 RGNLANVIRYFPTQALNFAFKDKYKQLFLGGVDRHKQFWRYFAGNLASGGAAGATSLC-- 129
Query: 382 LASYPLALVRTRMQAQAMLEGSPQLNMVGL---FRRIISKEGIPGLYRGITPNFMKVLPA 438
YPL RTR+ A +G+ Q GL +I +G+ GLY+G + ++
Sbjct: 130 -FVYPLDFARTRLAADVG-KGAAQREFHGLGDCIIKIFKSDGLRGLYQGFNVSVQGIIIY 187
Query: 439 VGISYVVYENMKQTL 453
+ VY+ K L
Sbjct: 188 RAAYFGVYDTAKGML 202
>gi|156071459 solute carrier family 25, member 5 [Homo sapiens]
Length = 298
Score = 131 bits (329), Expect = 1e-30
Identities = 90/293 (30%), Positives = 152/293 (51%), Gaps = 24/293 (8%)
Query: 177 RQLLAGGIAGAVSRTSTAPLDRLKIMMQV-HGSK---SDKM--NIFGGFRQMVKEGGIRS 230
+ LAGG+A A+S+T+ AP++R+K+++QV H SK +DK I ++ KE G+ S
Sbjct: 10 KDFLAGGVAAAISKTAVAPIERVKLLLQVQHASKQITADKQYKGIIDCVVRIPKEQGVLS 69
Query: 231 LWRGNGTNVIKIAPETAVKFWAYEQYKKLLTEEGQKIGTFERFISGSM-----AGATAQT 285
WRGN NVI+ P A+ F ++YK++ K F + +G++ AGAT+
Sbjct: 70 FWRGNLANVIRYFPTQALNFAFKDKYKQIFLGGVDKRTQFWLYFAGNLASGGAAGATSLC 129
Query: 286 FIYPMEVMKTRLA--VGKTG---QYSGIYDCAKKILKHEGLGAFYKGYVPNLLGIIPYAG 340
F+YP++ +TRLA VGK G ++ G+ DC KI K +G+ Y+G+ ++ GII Y
Sbjct: 130 FVYPLDFARTRLAADVGKAGAEREFRGLGDCLVKIYKSDGIKGLYQGFNVSVQGIIIYRA 189
Query: 341 IDLAVYELLKSYWLDNFAKDSVNPGVMVLLGCGALSSTCGQLASYPLALVRTRMQAQAML 400
+Y+ K D N +++ + L SYP VR RM Q+
Sbjct: 190 AYFGIYDTAK-----GMLPDPKNTHIVISWMIAQTVTAVAGLTSYPFDTVRRRMMMQSGR 244
Query: 401 EGSPQL--NMVGLFRRIISKEGIPGLYRGITPNFMKVLPAVGISYVVYENMKQ 451
+G+ + + +R+I EG ++G N ++ + + V+Y+ +K+
Sbjct: 245 KGTDIMYTGTLDCWRKIARDEGGKAFFKGAWSNVLRGMGGAFV-LVLYDEIKK 296
Score = 63.9 bits (154), Expect = 3e-10
Identities = 49/194 (25%), Positives = 86/194 (44%), Gaps = 16/194 (8%)
Query: 273 FISGSMAGATAQTFIYPMEVMKTRLAVGKTG-------QYSGIYDCAKKILKHEGLGAFY 325
F++G +A A ++T + P+E +K L V QY GI DC +I K +G+ +F+
Sbjct: 12 FLAGGVAAAISKTAVAPIERVKLLLQVQHASKQITADKQYKGIIDCVVRIPKEQGVLSFW 71
Query: 326 KGYVPNLLGIIPYAGIDLAVYELLKSYWLDNFAKDS----VNPGVMVLLGCGALSSTCGQ 381
+G + N++ P ++ A + K +L K + G + G +S C
Sbjct: 72 RGNLANVIRYFPTQALNFAFKDKYKQIFLGGVDKRTQFWLYFAGNLASGGAAGATSLC-- 129
Query: 382 LASYPLALVRTRMQAQAMLEGSPQ--LNMVGLFRRIISKEGIPGLYRGITPNFMKVLPAV 439
YPL RTR+ A G+ + + +I +GI GLY+G + ++
Sbjct: 130 -FVYPLDFARTRLAADVGKAGAEREFRGLGDCLVKIYKSDGIKGLYQGFNVSVQGIIIYR 188
Query: 440 GISYVVYENMKQTL 453
+ +Y+ K L
Sbjct: 189 AAYFGIYDTAKGML 202
>gi|21687151 mitochondrial solute carrier protein [Homo sapiens]
Length = 341
Score = 127 bits (319), Expect = 2e-29
Identities = 80/283 (28%), Positives = 145/283 (51%), Gaps = 12/283 (4%)
Query: 177 RQLLAGGIAGAVSRTSTAPLDRLKIMMQVHGSKSDKMNIFGGFRQMVKEGGIRSLWRGNG 236
++LL G+AG +S + TAPL+ ++ QV + + ++ + G+R+LW+GN
Sbjct: 14 QRLLCAGLAGTLSLSLTAPLELATVLAQVGVVRGHARGPWATGHRVWRAEGLRALWKGNA 73
Query: 237 TNVIKIAPETAVKFWAYEQYKKLLTEEGQKIGTFERFISGSMAGATAQTFIYPMEVMKTR 296
+++ P +AV+ AY ++ L T++ I + ++GS+AG + YP +++KTR
Sbjct: 74 VACLRLFPCSAVQLAAYRKFVVLFTDDLGHISQWSSIMAGSLAGMVSTIVTYPTDLIKTR 133
Query: 297 LAVGK--TGQYSGIYDCAKKILKHEGLGAFYKGYVPNLLGIIPYAGIDLAVYELLKSYWL 354
L + Y G+ I + EG A Y+G ++G +P++ L VY L+ W
Sbjct: 134 LIMQNILEPSYRGLLHAFSTIYQQEGFLALYRGVSLTVVGALPFSAGSLLVYMNLEKIW- 192
Query: 355 DNFAKDSVNPGVMVLLGCGALSSTCGQLASYPLALVRTRMQAQAML---EGSPQLNMVG- 410
N +D + C L++ Q S+P V+ +MQAQ+ G ++ G
Sbjct: 193 -NGPRDQFSLPQNFANVC--LAAAVTQTLSFPFETVKRKMQAQSPYLPHSGGVDVHFSGA 249
Query: 411 --LFRRIISKEGIPGLYRGITPNFMKVLPAVGISYVVYENMKQ 451
FR+I+ +G+ GL+ G+T N +K++P GI + +E K+
Sbjct: 250 VDCFRQIVKAQGVLGLWNGLTANLLKIVPYFGIMFSTFEFCKR 292
Score = 80.5 bits (197), Expect = 3e-15
Identities = 52/196 (26%), Positives = 88/196 (44%), Gaps = 11/196 (5%)
Query: 165 FTEDEKKSGQWWRQLLAGGIAGAVSRTSTAPLDRLKIMMQVHG-SKSDKMNIFGGFRQMV 223
FT+D QW ++AG +AG VS T P D +K + + + + F +
Sbjct: 97 FTDDLGHISQW-SSIMAGSLAGMVSTIVTYPTDLIKTRLIMQNILEPSYRGLLHAFSTIY 155
Query: 224 KEGGIRSLWRGNGTNVIKIAPETAVKFWAYEQYKKLLTEEGQKIGTFERFISGSMAGATA 283
++ G +L+RG V+ P +A Y +K+ + + F + +A A
Sbjct: 156 QQEGFLALYRGVSLTVVGALPFSAGSLLVYMNLEKIWNGPRDQFSLPQNFANVCLAAAVT 215
Query: 284 QTFIYPMEVMKTRLAV---------GKTGQYSGIYDCAKKILKHEGLGAFYKGYVPNLLG 334
QT +P E +K ++ G +SG DC ++I+K +G+ + G NLL
Sbjct: 216 QTLSFPFETVKRKMQAQSPYLPHSGGVDVHFSGAVDCFRQIVKAQGVLGLWNGLTANLLK 275
Query: 335 IIPYAGIDLAVYELLK 350
I+PY GI + +E K
Sbjct: 276 IVPYFGIMFSTFEFCK 291
Score = 42.0 bits (97), Expect = 0.001
Identities = 27/84 (32%), Positives = 44/84 (52%), Gaps = 8/84 (9%)
Query: 184 IAGAVSRTSTAPLDRLKIMMQVHGS---KSDKMNI-FGG----FRQMVKEGGIRSLWRGN 235
+A AV++T + P + +K MQ S +++ F G FRQ+VK G+ LW G
Sbjct: 210 LAAAVTQTLSFPFETVKRKMQAQSPYLPHSGGVDVHFSGAVDCFRQIVKAQGVLGLWNGL 269
Query: 236 GTNVIKIAPETAVKFWAYEQYKKL 259
N++KI P + F +E K++
Sbjct: 270 TANLLKIVPYFGIMFSTFEFCKRI 293
>gi|21314739 solute carrier family 25, member 32 [Homo sapiens]
Length = 315
Score = 119 bits (297), Expect = 7e-27
Identities = 86/290 (29%), Positives = 132/290 (45%), Gaps = 17/290 (5%)
Query: 176 WRQLLAGGIAGAVSRTSTAPLDRLKIMMQVHGSKSDKMNIFGGFRQMV---KEGGIRSLW 232
+ L+AG G +S + PLD +KI V + G + K G+R L+
Sbjct: 23 YENLIAGVSGGVLSNLALHPLDLVKIRFAVSDGLELRPKYNGILHCLTTIWKLDGLRGLY 82
Query: 233 RGNGTNVIKIAPETAVKFWAYEQYKKLLTE-EGQKIGTFERFISGSMAGATAQTFIYPME 291
+G N+ + F+ Y K TE +++ E +S + AGA P+
Sbjct: 83 QGVTPNIWGAGLSWGLYFFFYNAIKSYKTEGRAERLEATEYLVSAAEAGAMTLCITNPLW 142
Query: 292 VMKTRLAVGKTG-------QYSGIYDCAKKILKHEGLGAFYKGYVPNLLGIIPYAGIDLA 344
V KTRL + QY G++D KI K+EG+ YKG+VP L G + +
Sbjct: 143 VTKTRLMLQYDAVVNSPHRQYKGMFDTLVKIYKYEGVRGLYKGFVPGLFGT-SHGALQFM 201
Query: 345 VYELLKSYWLDNFAK-DSVNPGVMVLLGCGALSSTCGQLASYPLALVRTRMQAQAMLEGS 403
YELLK + + + + + ALS A+YP +VR R+Q Q M
Sbjct: 202 AYELLKLKYNQHINRLPEAQLSTVEYISVAALSKIFAVAATYPYQVVRARLQDQHMFYSG 261
Query: 404 PQLNMVGLFRRIISKEGIPGLYRGITPNFMKVLPAVGISYVVYENMKQTL 453
++ + + KEG+ G Y+GI PN ++V PA I++VVYEN+ L
Sbjct: 262 ----VIDVITKTWRKEGVGGFYKGIAPNLIRVTPACCITFVVYENVSHFL 307
Score = 65.9 bits (159), Expect = 8e-11
Identities = 52/188 (27%), Positives = 88/188 (46%), Gaps = 13/188 (6%)
Query: 179 LLAGGIAGAVSRTSTAPL--DRLKIMMQ----VHGSKSDKMNIFGGFRQMVKEGGIRSLW 232
L++ AGA++ T PL + ++M+Q V+ +F ++ K G+R L+
Sbjct: 124 LVSAAEAGAMTLCITNPLWVTKTRLMLQYDAVVNSPHRQYKGMFDTLVKIYKYEGVRGLY 183
Query: 233 RGNGTNVIKIAPETAVKFWAYEQYKKLLTEEGQKI-----GTFERFISGSMAGATAQTFI 287
+G + + A++F AYE K + ++ T E +++ A
Sbjct: 184 KGFVPGLFGTS-HGALQFMAYELLKLKYNQHINRLPEAQLSTVEYISVAALSKIFAVAAT 242
Query: 288 YPMEVMKTRLAVGKTGQYSGIYDCAKKILKHEGLGAFYKGYVPNLLGIIPYAGIDLAVYE 347
YP +V++ RL + YSG+ D K + EG+G FYKG PNL+ + P I VYE
Sbjct: 243 YPYQVVRARLQ-DQHMFYSGVIDVITKTWRKEGVGGFYKGIAPNLIRVTPACCITFVVYE 301
Query: 348 LLKSYWLD 355
+ + LD
Sbjct: 302 NVSHFLLD 309
>gi|186928856 solute carrier family 25, member 19 [Homo sapiens]
Length = 320
Score = 109 bits (273), Expect = 5e-24
Identities = 79/287 (27%), Positives = 136/287 (47%), Gaps = 21/287 (7%)
Query: 180 LAGGIAGAVSRTSTAPLDRLKIMMQVHG---SKSDKMNIFGGF----RQMVKEGGIRSLW 232
+AG ++G V+R +P D +KI Q+ S+SD + G RQ+++E G + W
Sbjct: 20 VAGSVSGLVTRALISPFDVIKIRFQLQHERLSRSDPSAKYHGILQASRQILQEEGPTAFW 79
Query: 233 RGNGTNVIKIAPETAVKFWAYEQYKKLLTEEGQKIGTFE---RFISGSMAGATAQTFIYP 289
+G+ I AV+F ++E +L+ G E F+ G +A A ++P
Sbjct: 80 KGHVPAQILSIGYGAVQFLSFEMLTELV-HRGSVYDAREFSVHFVCGGLAACMATLTVHP 138
Query: 290 MEVMKTRLAV-GKTGQYSGIYDCAKKILKHEGLGAFYKGYVPNLLGIIPYAGIDLAVYEL 348
++V++TR A G+ Y+ + + + EG FYKG P L+ I PYAG+ + Y
Sbjct: 139 VDVLRTRFAAQGEPKVYNTLRHAVGTMYRSEGPQVFYKGLAPTLIAIFPYAGLQFSCYSS 198
Query: 349 LKS-YWLDNFAKDSVNPGVMVLLGCGALSSTCGQLASYPLALVRTRMQAQAMLEGSPQLN 407
LK Y A+ N + LL CG+ + + +YPL L + R+Q
Sbjct: 199 LKHLYKWAIPAEGKKNENLQNLL-CGSGAGVISKTLTYPLDLFKKRLQVGGFEHARAAFG 257
Query: 408 MVGLF-------RRIISKEGIPGLYRGITPNFMKVLPAVGISYVVYE 447
V + ++++ KEG G ++G++P+ +K + G + YE
Sbjct: 258 QVRRYKGLMDCAKQVLQKEGALGFFKGLSPSLLKAALSTGFMFFSYE 304
Score = 77.0 bits (188), Expect = 3e-14
Identities = 53/201 (26%), Positives = 95/201 (47%), Gaps = 22/201 (10%)
Query: 263 EGQKIGTFERFISGSMAGATAQTFIYPMEVMKTRLAV--------GKTGQYSGIYDCAKK 314
+G+ F+ ++GS++G + I P +V+K R + + +Y GI +++
Sbjct: 9 DGRNNTKFQVAVAGSVSGLVTRALISPFDVIKIRFQLQHERLSRSDPSAKYHGILQASRQ 68
Query: 315 ILKHEGLGAFYKGYVPNLLGIIPYAGIDLAVYELLKSYWLDNFAKDSVNPGVMVLLGCGA 374
IL+ EG AF+KG+VP + I Y + +E+L D+ V + CG
Sbjct: 69 ILQEEGPTAFWKGHVPAQILSIGYGAVQFLSFEMLTELVHRGSVYDAREFSVHFV--CGG 126
Query: 375 LSSTCGQLASYPLALVRTRMQAQAMLEGSPQL-----NMVGLFRRIISKEGIPGLYRGIT 429
L++ L +P+ ++RTR AQ G P++ + VG R EG Y+G+
Sbjct: 127 LAACMATLTVHPVDVLRTRFAAQ----GEPKVYNTLRHAVGTMYR---SEGPQVFYKGLA 179
Query: 430 PNFMKVLPAVGISYVVYENMK 450
P + + P G+ + Y ++K
Sbjct: 180 PTLIAIFPYAGLQFSCYSSLK 200
Score = 41.2 bits (95), Expect = 0.002
Identities = 29/96 (30%), Positives = 47/96 (48%), Gaps = 11/96 (11%)
Query: 169 EKKSGQWWRQLLAGGIAGAVSRTSTAPLDRLKIMMQVHGSKSDKMNIFGGFR-------- 220
E K + + LL G AG +S+T T PLD K +QV G + + FG R
Sbjct: 210 EGKKNENLQNLLCGSGAGVISKTLTYPLDLFKKRLQVGGFEHARA-AFGQVRRYKGLMDC 268
Query: 221 --QMVKEGGIRSLWRGNGTNVIKIAPETAVKFWAYE 254
Q++++ G ++G +++K A T F++YE
Sbjct: 269 AKQVLQKEGALGFFKGLSPSLLKAALSTGFMFFSYE 304
>gi|186928860 solute carrier family 25, member 19 [Homo sapiens]
Length = 320
Score = 109 bits (273), Expect = 5e-24
Identities = 79/287 (27%), Positives = 136/287 (47%), Gaps = 21/287 (7%)
Query: 180 LAGGIAGAVSRTSTAPLDRLKIMMQVHG---SKSDKMNIFGGF----RQMVKEGGIRSLW 232
+AG ++G V+R +P D +KI Q+ S+SD + G RQ+++E G + W
Sbjct: 20 VAGSVSGLVTRALISPFDVIKIRFQLQHERLSRSDPSAKYHGILQASRQILQEEGPTAFW 79
Query: 233 RGNGTNVIKIAPETAVKFWAYEQYKKLLTEEGQKIGTFE---RFISGSMAGATAQTFIYP 289
+G+ I AV+F ++E +L+ G E F+ G +A A ++P
Sbjct: 80 KGHVPAQILSIGYGAVQFLSFEMLTELV-HRGSVYDAREFSVHFVCGGLAACMATLTVHP 138
Query: 290 MEVMKTRLAV-GKTGQYSGIYDCAKKILKHEGLGAFYKGYVPNLLGIIPYAGIDLAVYEL 348
++V++TR A G+ Y+ + + + EG FYKG P L+ I PYAG+ + Y
Sbjct: 139 VDVLRTRFAAQGEPKVYNTLRHAVGTMYRSEGPQVFYKGLAPTLIAIFPYAGLQFSCYSS 198
Query: 349 LKS-YWLDNFAKDSVNPGVMVLLGCGALSSTCGQLASYPLALVRTRMQAQAMLEGSPQLN 407
LK Y A+ N + LL CG+ + + +YPL L + R+Q
Sbjct: 199 LKHLYKWAIPAEGKKNENLQNLL-CGSGAGVISKTLTYPLDLFKKRLQVGGFEHARAAFG 257
Query: 408 MVGLF-------RRIISKEGIPGLYRGITPNFMKVLPAVGISYVVYE 447
V + ++++ KEG G ++G++P+ +K + G + YE
Sbjct: 258 QVRRYKGLMDCAKQVLQKEGALGFFKGLSPSLLKAALSTGFMFFSYE 304
Score = 77.0 bits (188), Expect = 3e-14
Identities = 53/201 (26%), Positives = 95/201 (47%), Gaps = 22/201 (10%)
Query: 263 EGQKIGTFERFISGSMAGATAQTFIYPMEVMKTRLAV--------GKTGQYSGIYDCAKK 314
+G+ F+ ++GS++G + I P +V+K R + + +Y GI +++
Sbjct: 9 DGRNNTKFQVAVAGSVSGLVTRALISPFDVIKIRFQLQHERLSRSDPSAKYHGILQASRQ 68
Query: 315 ILKHEGLGAFYKGYVPNLLGIIPYAGIDLAVYELLKSYWLDNFAKDSVNPGVMVLLGCGA 374
IL+ EG AF+KG+VP + I Y + +E+L D+ V + CG
Sbjct: 69 ILQEEGPTAFWKGHVPAQILSIGYGAVQFLSFEMLTELVHRGSVYDAREFSVHFV--CGG 126
Query: 375 LSSTCGQLASYPLALVRTRMQAQAMLEGSPQL-----NMVGLFRRIISKEGIPGLYRGIT 429
L++ L +P+ ++RTR AQ G P++ + VG R EG Y+G+
Sbjct: 127 LAACMATLTVHPVDVLRTRFAAQ----GEPKVYNTLRHAVGTMYR---SEGPQVFYKGLA 179
Query: 430 PNFMKVLPAVGISYVVYENMK 450
P + + P G+ + Y ++K
Sbjct: 180 PTLIAIFPYAGLQFSCYSSLK 200
Score = 41.2 bits (95), Expect = 0.002
Identities = 29/96 (30%), Positives = 47/96 (48%), Gaps = 11/96 (11%)
Query: 169 EKKSGQWWRQLLAGGIAGAVSRTSTAPLDRLKIMMQVHGSKSDKMNIFGGFR-------- 220
E K + + LL G AG +S+T T PLD K +QV G + + FG R
Sbjct: 210 EGKKNENLQNLLCGSGAGVISKTLTYPLDLFKKRLQVGGFEHARA-AFGQVRRYKGLMDC 268
Query: 221 --QMVKEGGIRSLWRGNGTNVIKIAPETAVKFWAYE 254
Q++++ G ++G +++K A T F++YE
Sbjct: 269 AKQVLQKEGALGFFKGLSPSLLKAALSTGFMFFSYE 304
>gi|186928858 solute carrier family 25, member 19 [Homo sapiens]
Length = 320
Score = 109 bits (273), Expect = 5e-24
Identities = 79/287 (27%), Positives = 136/287 (47%), Gaps = 21/287 (7%)
Query: 180 LAGGIAGAVSRTSTAPLDRLKIMMQVHG---SKSDKMNIFGGF----RQMVKEGGIRSLW 232
+AG ++G V+R +P D +KI Q+ S+SD + G RQ+++E G + W
Sbjct: 20 VAGSVSGLVTRALISPFDVIKIRFQLQHERLSRSDPSAKYHGILQASRQILQEEGPTAFW 79
Query: 233 RGNGTNVIKIAPETAVKFWAYEQYKKLLTEEGQKIGTFE---RFISGSMAGATAQTFIYP 289
+G+ I AV+F ++E +L+ G E F+ G +A A ++P
Sbjct: 80 KGHVPAQILSIGYGAVQFLSFEMLTELV-HRGSVYDAREFSVHFVCGGLAACMATLTVHP 138
Query: 290 MEVMKTRLAV-GKTGQYSGIYDCAKKILKHEGLGAFYKGYVPNLLGIIPYAGIDLAVYEL 348
++V++TR A G+ Y+ + + + EG FYKG P L+ I PYAG+ + Y
Sbjct: 139 VDVLRTRFAAQGEPKVYNTLRHAVGTMYRSEGPQVFYKGLAPTLIAIFPYAGLQFSCYSS 198
Query: 349 LKS-YWLDNFAKDSVNPGVMVLLGCGALSSTCGQLASYPLALVRTRMQAQAMLEGSPQLN 407
LK Y A+ N + LL CG+ + + +YPL L + R+Q
Sbjct: 199 LKHLYKWAIPAEGKKNENLQNLL-CGSGAGVISKTLTYPLDLFKKRLQVGGFEHARAAFG 257
Query: 408 MVGLF-------RRIISKEGIPGLYRGITPNFMKVLPAVGISYVVYE 447
V + ++++ KEG G ++G++P+ +K + G + YE
Sbjct: 258 QVRRYKGLMDCAKQVLQKEGALGFFKGLSPSLLKAALSTGFMFFSYE 304
Score = 77.0 bits (188), Expect = 3e-14
Identities = 53/201 (26%), Positives = 95/201 (47%), Gaps = 22/201 (10%)
Query: 263 EGQKIGTFERFISGSMAGATAQTFIYPMEVMKTRLAV--------GKTGQYSGIYDCAKK 314
+G+ F+ ++GS++G + I P +V+K R + + +Y GI +++
Sbjct: 9 DGRNNTKFQVAVAGSVSGLVTRALISPFDVIKIRFQLQHERLSRSDPSAKYHGILQASRQ 68
Query: 315 ILKHEGLGAFYKGYVPNLLGIIPYAGIDLAVYELLKSYWLDNFAKDSVNPGVMVLLGCGA 374
IL+ EG AF+KG+VP + I Y + +E+L D+ V + CG
Sbjct: 69 ILQEEGPTAFWKGHVPAQILSIGYGAVQFLSFEMLTELVHRGSVYDAREFSVHFV--CGG 126
Query: 375 LSSTCGQLASYPLALVRTRMQAQAMLEGSPQL-----NMVGLFRRIISKEGIPGLYRGIT 429
L++ L +P+ ++RTR AQ G P++ + VG R EG Y+G+
Sbjct: 127 LAACMATLTVHPVDVLRTRFAAQ----GEPKVYNTLRHAVGTMYR---SEGPQVFYKGLA 179
Query: 430 PNFMKVLPAVGISYVVYENMK 450
P + + P G+ + Y ++K
Sbjct: 180 PTLIAIFPYAGLQFSCYSSLK 200
Score = 41.2 bits (95), Expect = 0.002
Identities = 29/96 (30%), Positives = 47/96 (48%), Gaps = 11/96 (11%)
Query: 169 EKKSGQWWRQLLAGGIAGAVSRTSTAPLDRLKIMMQVHGSKSDKMNIFGGFR-------- 220
E K + + LL G AG +S+T T PLD K +QV G + + FG R
Sbjct: 210 EGKKNENLQNLLCGSGAGVISKTLTYPLDLFKKRLQVGGFEHARA-AFGQVRRYKGLMDC 268
Query: 221 --QMVKEGGIRSLWRGNGTNVIKIAPETAVKFWAYE 254
Q++++ G ++G +++K A T F++YE
Sbjct: 269 AKQVLQKEGALGFFKGLSPSLLKAALSTGFMFFSYE 304
>gi|157388989 solute carrier family 25, member 36 isoform a [Homo
sapiens]
Length = 311
Score = 108 bits (270), Expect = 1e-23
Identities = 82/299 (27%), Positives = 135/299 (45%), Gaps = 35/299 (11%)
Query: 179 LLAGGIAGAVSRTSTAPLDRLKIMMQVHGS----KSDKMNIFGG--------------FR 220
L AGG G V T PL+ +K +Q ++N G +
Sbjct: 10 LFAGGCGGTVGAILTCPLEVVKTRLQSSSVTLYISEVQLNTMAGASVNRVVSPGPLHCLK 69
Query: 221 QMVKEGGIRSLWRGNGTNVIKIAPETAVKFWAYEQYKKLLTEEGQKIGTFERFISGSMAG 280
++++ G RSL+RG G N++ +AP A+ F AY K+ L + T IS +MAG
Sbjct: 70 VILEKEGPRSLFRGLGPNLVGVAPSRAIYFAAYSNCKEKLNDVFDPDSTQVHMISAAMAG 129
Query: 281 ATAQTFIYPMEVMKTRL---AVGKTGQYSGIYDCAKKILKHEGLGAFYKGYVPNLLGIIP 337
TA T P+ ++KTRL A + + G ++C +K+ + +GL FY+G + GI
Sbjct: 130 FTAITATNPIWLIKTRLQLDARNRGERRMGAFECVRKVYQTDGLKGFYRGMSASYAGISE 189
Query: 338 YAGIDLAVYELLKSYWLDNFAKDSVN---------PGVMVLLGCGALSSTCGQLASYPLA 388
I +YE +K L+ ++ + ++ A S TC +YP
Sbjct: 190 TV-IHFVIYESIKQKLLEYKTASTMENDEESVKEASDFVGMMLAAATSKTCATTIAYPHE 248
Query: 389 LVRTRMQAQAMLEGSPQLNMVGLFRRIISKEGIPGLYRGITPNFMKVLPAVGISYVVYE 447
+VRTR++ EG+ + ++ +EG LYRG+T + ++ +P I YE
Sbjct: 249 VVRTRLRE----EGTKYRSFFQTLSLLVQEEGYGSLYRGLTTHLVRQIPNTAIMMATYE 303
Score = 80.1 bits (196), Expect = 4e-15
Identities = 56/204 (27%), Positives = 88/204 (43%), Gaps = 24/204 (11%)
Query: 269 TFERFISGSMAGATAQTFIYPMEVMKTRLAVGKTGQY-------------------SGIY 309
T +G G P+EV+KTRL Y G
Sbjct: 6 TLVHLFAGGCGGTVGAILTCPLEVVKTRLQSSSVTLYISEVQLNTMAGASVNRVVSPGPL 65
Query: 310 DCAKKILKHEGLGAFYKGYVPNLLGIIPYAGIDLAVYELLKSYWLDNFAKDSVNPGVMVL 369
C K IL+ EG + ++G PNL+G+ P I A Y K D F DS V
Sbjct: 66 HCLKVILEKEGPRSLFRGLGPNLVGVAPSRAIYFAAYSNCKEKLNDVFDPDS----TQVH 121
Query: 370 LGCGALSSTCGQLASYPLALVRTRMQAQAMLEGSPQLNMVGLFRRIISKEGIPGLYRGIT 429
+ A++ A+ P+ L++TR+Q A G ++ R++ +G+ G YRG++
Sbjct: 122 MISAAMAGFTAITATNPIWLIKTRLQLDARNRGERRMGAFECVRKVYQTDGLKGFYRGMS 181
Query: 430 PNFMKVLPAVGISYVVYENMKQTL 453
++ + V I +V+YE++KQ L
Sbjct: 182 ASYAGISETV-IHFVIYESIKQKL 204
Score = 68.9 bits (167), Expect = 9e-12
Identities = 50/186 (26%), Positives = 89/186 (47%), Gaps = 17/186 (9%)
Query: 179 LLAGGIAGAVSRTSTAPLDRLKIMMQVHGSKSD--KMNIFGGFRQMVKEGGIRSLWRGNG 236
+++ +AG + T+T P+ +K +Q+ +M F R++ + G++ +RG
Sbjct: 122 MISAAMAGFTAITATNPIWLIKTRLQLDARNRGERRMGAFECVRKVYQTDGLKGFYRGMS 181
Query: 237 TNVIKIAPETAVKFWAYEQYKKLLTE---------EGQKIGTFERFISGSMAGAT----A 283
+ I+ ET + F YE K+ L E + + + F+ +A AT A
Sbjct: 182 ASYAGIS-ETVIHFVIYESIKQKLLEYKTASTMENDEESVKEASDFVGMMLAAATSKTCA 240
Query: 284 QTFIYPMEVMKTRLAVGKTGQYSGIYDCAKKILKHEGLGAFYKGYVPNLLGIIPYAGIDL 343
T YP EV++TRL T +Y + +++ EG G+ Y+G +L+ IP I +
Sbjct: 241 TTIAYPHEVVRTRLREEGT-KYRSFFQTLSLLVQEEGYGSLYRGLTTHLVRQIPNTAIMM 299
Query: 344 AVYELL 349
A YEL+
Sbjct: 300 ATYELV 305
Score = 35.4 bits (80), Expect = 0.11
Identities = 24/94 (25%), Positives = 45/94 (47%), Gaps = 2/94 (2%)
Query: 167 EDEKKSGQWWRQLLAGGIAGAVSRTSTAPLDRLKIMMQVHGSKSDKMNIFGGFRQMVKEG 226
E K++ + +LA + + T P + ++ ++ G+K + F +V+E
Sbjct: 218 ESVKEASDFVGMMLAAATSKTCATTIAYPHEVVRTRLREEGTKY--RSFFQTLSLLVQEE 275
Query: 227 GIRSLWRGNGTNVIKIAPETAVKFWAYEQYKKLL 260
G SL+RG T++++ P TA+ YE LL
Sbjct: 276 GYGSLYRGLTTHLVRQIPNTAIMMATYELVVYLL 309
>gi|157388991 solute carrier family 25, member 36 isoform b [Homo
sapiens]
Length = 310
Score = 104 bits (260), Expect = 1e-22
Identities = 82/299 (27%), Positives = 135/299 (45%), Gaps = 36/299 (12%)
Query: 179 LLAGGIAGAVSRTSTAPLDRLKIMMQVHGS----KSDKMNIFGG--------------FR 220
L AGG G V T PL+ +K +Q ++N G +
Sbjct: 10 LFAGGCGGTVGAILTCPLEVVKTRLQSSSVTLYISEVQLNTMAGASVNRVVSPGPLHCLK 69
Query: 221 QMVKEGGIRSLWRGNGTNVIKIAPETAVKFWAYEQYKKLLTEEGQKIGTFERFISGSMAG 280
++++ G RSL+RG G N++ +AP A+ F AY K+ L + T IS +MAG
Sbjct: 70 VILEKEGPRSLFRGLGPNLVGVAPSRAIYFAAYSNCKEKLNDVFDPDSTQVHMISAAMAG 129
Query: 281 ATAQTFIYPMEVMKTRL---AVGKTGQYSGIYDCAKKILKHEGLGAFYKGYVPNLLGIIP 337
TA T P+ ++KTRL A + + G ++C +K+ + +GL FY+G + GI
Sbjct: 130 FTAITATNPIWLIKTRLQLDARNRGERRMGAFECVRKVYQTDGLKGFYRGMSASYAGISE 189
Query: 338 YAGIDLAVYELLKSYWLDNFAKDSVN---------PGVMVLLGCGALSSTCGQLASYPLA 388
I +YE +K L+ ++ + ++ A S TC +YP
Sbjct: 190 TV-IHFVIYESIKQKLLEYKTASTMENDEESVKEASDFVGMMLAAATSKTCATTIAYP-H 247
Query: 389 LVRTRMQAQAMLEGSPQLNMVGLFRRIISKEGIPGLYRGITPNFMKVLPAVGISYVVYE 447
+VRTR++ EG+ + ++ +EG LYRG+T + ++ +P I YE
Sbjct: 248 VVRTRLRE----EGTKYRSFFQTLSLLVQEEGYGSLYRGLTTHLVRQIPNTAIMMATYE 302
Score = 80.1 bits (196), Expect = 4e-15
Identities = 56/204 (27%), Positives = 88/204 (43%), Gaps = 24/204 (11%)
Query: 269 TFERFISGSMAGATAQTFIYPMEVMKTRLAVGKTGQY-------------------SGIY 309
T +G G P+EV+KTRL Y G
Sbjct: 6 TLVHLFAGGCGGTVGAILTCPLEVVKTRLQSSSVTLYISEVQLNTMAGASVNRVVSPGPL 65
Query: 310 DCAKKILKHEGLGAFYKGYVPNLLGIIPYAGIDLAVYELLKSYWLDNFAKDSVNPGVMVL 369
C K IL+ EG + ++G PNL+G+ P I A Y K D F DS V
Sbjct: 66 HCLKVILEKEGPRSLFRGLGPNLVGVAPSRAIYFAAYSNCKEKLNDVFDPDS----TQVH 121
Query: 370 LGCGALSSTCGQLASYPLALVRTRMQAQAMLEGSPQLNMVGLFRRIISKEGIPGLYRGIT 429
+ A++ A+ P+ L++TR+Q A G ++ R++ +G+ G YRG++
Sbjct: 122 MISAAMAGFTAITATNPIWLIKTRLQLDARNRGERRMGAFECVRKVYQTDGLKGFYRGMS 181
Query: 430 PNFMKVLPAVGISYVVYENMKQTL 453
++ + V I +V+YE++KQ L
Sbjct: 182 ASYAGISETV-IHFVIYESIKQKL 204
Score = 63.2 bits (152), Expect = 5e-10
Identities = 49/186 (26%), Positives = 88/186 (47%), Gaps = 18/186 (9%)
Query: 179 LLAGGIAGAVSRTSTAPLDRLKIMMQVHGSKSD--KMNIFGGFRQMVKEGGIRSLWRGNG 236
+++ +AG + T+T P+ +K +Q+ +M F R++ + G++ +RG
Sbjct: 122 MISAAMAGFTAITATNPIWLIKTRLQLDARNRGERRMGAFECVRKVYQTDGLKGFYRGMS 181
Query: 237 TNVIKIAPETAVKFWAYEQYKKLLTE---------EGQKIGTFERFISGSMAGAT----A 283
+ I+ ET + F YE K+ L E + + + F+ +A AT A
Sbjct: 182 ASYAGIS-ETVIHFVIYESIKQKLLEYKTASTMENDEESVKEASDFVGMMLAAATSKTCA 240
Query: 284 QTFIYPMEVMKTRLAVGKTGQYSGIYDCAKKILKHEGLGAFYKGYVPNLLGIIPYAGIDL 343
T YP V++TRL T +Y + +++ EG G+ Y+G +L+ IP I +
Sbjct: 241 TTIAYP-HVVRTRLREEGT-KYRSFFQTLSLLVQEEGYGSLYRGLTTHLVRQIPNTAIMM 298
Query: 344 AVYELL 349
A YEL+
Sbjct: 299 ATYELV 304
Score = 30.8 bits (68), Expect = 2.7
Identities = 24/94 (25%), Positives = 44/94 (46%), Gaps = 3/94 (3%)
Query: 167 EDEKKSGQWWRQLLAGGIAGAVSRTSTAPLDRLKIMMQVHGSKSDKMNIFGGFRQMVKEG 226
E K++ + +LA + + T P ++ ++ G+K + F +V+E
Sbjct: 218 ESVKEASDFVGMMLAAATSKTCATTIAYP-HVVRTRLREEGTKY--RSFFQTLSLLVQEE 274
Query: 227 GIRSLWRGNGTNVIKIAPETAVKFWAYEQYKKLL 260
G SL+RG T++++ P TA+ YE LL
Sbjct: 275 GYGSLYRGLTTHLVRQIPNTAIMMATYELVVYLL 308
>gi|4507009 solute carrier family 25, member 14 isoform UCP5L [Homo
sapiens]
Length = 325
Score = 104 bits (260), Expect = 1e-22
Identities = 77/296 (26%), Positives = 130/296 (43%), Gaps = 14/296 (4%)
Query: 166 TEDEKKSGQWWRQLLAGGIAGAVSRTSTAPLDRLKIMMQVHGSKSDKM-------NIFGG 218
T + SG W+ + GG+A V+ T P+D K +QV G D +F
Sbjct: 31 TVSHEMSGLNWKPFVYGGLASIVAEFGTFPVDLTKTRLQVQGQSIDARFKEIKYRGMFHA 90
Query: 219 FRQMVKEGGIRSLWRGNGTNVIKIAPETAVKFWAYEQYKKLLTEEGQKIGTFERFISGSM 278
++ KE G+ +L+ G +++ A +K Y+ K+L E + I G +
Sbjct: 91 LFRICKEEGVLALYSGIAPALLRQASYGTIKIGIYQSLKRLFVERLEDETLLINMICGVV 150
Query: 279 AGATAQTFIYPMEVMKTRLAVGKTGQYSGIYDCAKKILKHEGLGAFYKGYVPNLLGIIPY 338
+G + T P +V+K R+ + + I + EG ++G VP
Sbjct: 151 SGVISSTIANPTDVLKIRMQAQGSLFQGSMIGSFIDIYQQEGTRGLWRGVVPTAQRAAIV 210
Query: 339 AGIDLAVYELLKSYW-LDNFAKDSVNPGVMVLLGCGALSSTCGQLASYPLALVRTRMQAQ 397
G++L VY++ K + L D++ + CG G LAS P+ +VRTRM Q
Sbjct: 211 VGVELPVYDITKKHLILSGMMGDTILTHFVSSFTCG----LAGALASNPVDVVRTRMMNQ 266
Query: 398 AMLEGSPQL--NMVGLFRRIISKEGIPGLYRGITPNFMKVLPAVGISYVVYENMKQ 451
+ G L V ++ EG LY+G PN++++ P I ++ YE +K+
Sbjct: 267 RAIVGHVDLYKGTVDGILKMWKHEGFFALYKGFWPNWLRLGPWNIIFFITYEQLKR 322
Score = 88.6 bits (218), Expect = 1e-17
Identities = 56/189 (29%), Positives = 94/189 (49%), Gaps = 15/189 (7%)
Query: 273 FISGSMAGATAQTFIYPMEVMKTRLAVG--------KTGQYSGIYDCAKKILKHEGLGAF 324
F+ G +A A+ +P+++ KTRL V K +Y G++ +I K EG+ A
Sbjct: 44 FVYGGLASIVAEFGTFPVDLTKTRLQVQGQSIDARFKEIKYRGMFHALFRICKEEGVLAL 103
Query: 325 YKGYVPNLLGIIPYAGIDLAVYELLKSYWLDNFAKDSVNPGVMVLLGCGALSSTCGQLAS 384
Y G P LL Y I + +Y+ LK +++ ++ +++ + CG +S +
Sbjct: 104 YSGIAPALLRQASYGTIKIGIYQSLKRLFVERLEDET----LLINMICGVVSGVISSTIA 159
Query: 385 YPLALVRTRMQAQAMLEGSPQLNMVGLFRRIISKEGIPGLYRGITPNFMKVLPAVGISYV 444
P +++ RMQAQ L Q +M+G F I +EG GL+RG+ P + VG+
Sbjct: 160 NPTDVLKIRMQAQGSLF---QGSMIGSFIDIYQQEGTRGLWRGVVPTAQRAAIVVGVELP 216
Query: 445 VYENMKQTL 453
VY+ K+ L
Sbjct: 217 VYDITKKHL 225
Score = 31.6 bits (70), Expect = 1.6
Identities = 21/81 (25%), Positives = 41/81 (50%), Gaps = 7/81 (8%)
Query: 183 GIAGAVSRTSTAPLDRLKIMMQVHGSKSDKMNIF----GGFRQMVKEGGIRSLWRGNGTN 238
G+AGA++ P+D ++ M + ++++ G +M K G +L++G N
Sbjct: 246 GLAGALASN---PVDVVRTRMMNQRAIVGHVDLYKGTVDGILKMWKHEGFFALYKGFWPN 302
Query: 239 VIKIAPETAVKFWAYEQYKKL 259
+++ P + F YEQ K+L
Sbjct: 303 WLRLGPWNIIFFITYEQLKRL 323
>gi|13259543 solute carrier family 25, member 14 isoform UCP5S [Homo
sapiens]
Length = 322
Score = 104 bits (260), Expect = 1e-22
Identities = 77/296 (26%), Positives = 130/296 (43%), Gaps = 14/296 (4%)
Query: 166 TEDEKKSGQWWRQLLAGGIAGAVSRTSTAPLDRLKIMMQVHGSKSDKM-------NIFGG 218
T + SG W+ + GG+A V+ T P+D K +QV G D +F
Sbjct: 28 TVSHEMSGLNWKPFVYGGLASIVAEFGTFPVDLTKTRLQVQGQSIDARFKEIKYRGMFHA 87
Query: 219 FRQMVKEGGIRSLWRGNGTNVIKIAPETAVKFWAYEQYKKLLTEEGQKIGTFERFISGSM 278
++ KE G+ +L+ G +++ A +K Y+ K+L E + I G +
Sbjct: 88 LFRICKEEGVLALYSGIAPALLRQASYGTIKIGIYQSLKRLFVERLEDETLLINMICGVV 147
Query: 279 AGATAQTFIYPMEVMKTRLAVGKTGQYSGIYDCAKKILKHEGLGAFYKGYVPNLLGIIPY 338
+G + T P +V+K R+ + + I + EG ++G VP
Sbjct: 148 SGVISSTIANPTDVLKIRMQAQGSLFQGSMIGSFIDIYQQEGTRGLWRGVVPTAQRAAIV 207
Query: 339 AGIDLAVYELLKSYW-LDNFAKDSVNPGVMVLLGCGALSSTCGQLASYPLALVRTRMQAQ 397
G++L VY++ K + L D++ + CG G LAS P+ +VRTRM Q
Sbjct: 208 VGVELPVYDITKKHLILSGMMGDTILTHFVSSFTCG----LAGALASNPVDVVRTRMMNQ 263
Query: 398 AMLEGSPQL--NMVGLFRRIISKEGIPGLYRGITPNFMKVLPAVGISYVVYENMKQ 451
+ G L V ++ EG LY+G PN++++ P I ++ YE +K+
Sbjct: 264 RAIVGHVDLYKGTVDGILKMWKHEGFFALYKGFWPNWLRLGPWNIIFFITYEQLKR 319
Score = 88.6 bits (218), Expect = 1e-17
Identities = 56/189 (29%), Positives = 94/189 (49%), Gaps = 15/189 (7%)
Query: 273 FISGSMAGATAQTFIYPMEVMKTRLAVG--------KTGQYSGIYDCAKKILKHEGLGAF 324
F+ G +A A+ +P+++ KTRL V K +Y G++ +I K EG+ A
Sbjct: 41 FVYGGLASIVAEFGTFPVDLTKTRLQVQGQSIDARFKEIKYRGMFHALFRICKEEGVLAL 100
Query: 325 YKGYVPNLLGIIPYAGIDLAVYELLKSYWLDNFAKDSVNPGVMVLLGCGALSSTCGQLAS 384
Y G P LL Y I + +Y+ LK +++ ++ +++ + CG +S +
Sbjct: 101 YSGIAPALLRQASYGTIKIGIYQSLKRLFVERLEDET----LLINMICGVVSGVISSTIA 156
Query: 385 YPLALVRTRMQAQAMLEGSPQLNMVGLFRRIISKEGIPGLYRGITPNFMKVLPAVGISYV 444
P +++ RMQAQ L Q +M+G F I +EG GL+RG+ P + VG+
Sbjct: 157 NPTDVLKIRMQAQGSLF---QGSMIGSFIDIYQQEGTRGLWRGVVPTAQRAAIVVGVELP 213
Query: 445 VYENMKQTL 453
VY+ K+ L
Sbjct: 214 VYDITKKHL 222
Score = 31.6 bits (70), Expect = 1.6
Identities = 21/81 (25%), Positives = 41/81 (50%), Gaps = 7/81 (8%)
Query: 183 GIAGAVSRTSTAPLDRLKIMMQVHGSKSDKMNIF----GGFRQMVKEGGIRSLWRGNGTN 238
G+AGA++ P+D ++ M + ++++ G +M K G +L++G N
Sbjct: 243 GLAGALASN---PVDVVRTRMMNQRAIVGHVDLYKGTVDGILKMWKHEGFFALYKGFWPN 299
Query: 239 VIKIAPETAVKFWAYEQYKKL 259
+++ P + F YEQ K+L
Sbjct: 300 WLRLGPWNIIFFITYEQLKRL 320
>gi|21361103 solute carrier family 25, member 12 [Homo sapiens]
Length = 678
Score = 102 bits (254), Expect = 7e-22
Identities = 63/183 (34%), Positives = 99/183 (54%), Gaps = 5/183 (2%)
Query: 178 QLLAGGIAGAVSRTSTAPLDRLKIMMQVHGSKSDKMNIFGGFRQMVKEGGIRSLWRGNGT 237
++LAGG AG T PL+ +KI +QV G + + ++++ GI L++G
Sbjct: 429 EVLAGGCAGGSQVIFTNPLEIVKIRLQVAGEITTGPRVSA--LNVLRDLGIFGLYKGAKA 486
Query: 238 NVIKIAPETAVKFWAYEQYKKLLTEEGQKIGTFERFISGSMAGATAQTFIYPMEVMKTRL 297
++ P +A+ F Y K LL +E +G +G+MAG A + + P +V+KTRL
Sbjct: 487 CFLRDIPFSAIYFPVYAHCKLLLADENGHVGGLNLLAAGAMAGVPAASLVTPADVIKTRL 546
Query: 298 AVG-KTGQ--YSGIYDCAKKILKHEGLGAFYKGYVPNLLGIIPYAGIDLAVYELLKSYWL 354
V + GQ YSG+ DC +KIL+ EG AF+KG + P G+ L YELL+ ++
Sbjct: 547 QVAARAGQTTYSGVIDCFRKILREEGPSAFWKGTAARVFRSSPQFGVTLVTYELLQRWFY 606
Query: 355 DNF 357
+F
Sbjct: 607 IDF 609
Score = 98.2 bits (243), Expect = 1e-20
Identities = 72/277 (25%), Positives = 126/277 (45%), Gaps = 13/277 (4%)
Query: 182 GGIAGAVSRTSTAPLDRLKIMMQVHGSKSDKM------NIFGGFRQMVKEGGIRSLWRGN 235
G +AGAV T+ P+D +K MQ + N F F+++++ G L+RG
Sbjct: 333 GSVAGAVGATAVYPIDLVKTRMQNQRGSGSVVGELMYKNSFDCFKKVLRYEGFFGLYRGL 392
Query: 236 GTNVIKIAPETAVKFWAYEQYKKLLTEEGQKIGTFERFISGSMAGATAQTFIYPMEVMKT 295
+I +APE A+K + + T + ++G AG + F P+E++K
Sbjct: 393 IPQLIGVAPEKAIKLTVNDFVRDKFTRRDGSVPLPAEVLAGGCAGGSQVIFTNPLEIVKI 452
Query: 296 RLAVGKTGQY-SGIYDCAKKILKHEGLGAFYKGYVPNLLGIIPYAGIDLAVYELLKSYWL 354
RL V G+ +G A +L+ G+ YKG L IP++ I VY K
Sbjct: 453 RLQV--AGEITTGPRVSALNVLRDLGIFGLYKGAKACFLRDIPFSAIYFPVYAHCKLL-- 508
Query: 355 DNFAKDSVNPGVMVLLGCGALSSTCGQLASYPLALVRTRMQAQAMLEGSPQLNMVGLFRR 414
A ++ + G + LL GA++ P +++TR+Q A + ++ FR+
Sbjct: 509 --LADENGHVGGLNLLAAGAMAGVPAASLVTPADVIKTRLQVAARAGQTTYSGVIDCFRK 566
Query: 415 IISKEGIPGLYRGITPNFMKVLPAVGISYVVYENMKQ 451
I+ +EG ++G + P G++ V YE +++
Sbjct: 567 ILREEGPSAFWKGTAARVFRSSPQFGVTLVTYELLQR 603
Score = 90.9 bits (224), Expect = 2e-18
Identities = 58/193 (30%), Positives = 99/193 (51%), Gaps = 23/193 (11%)
Query: 272 RFISGSMAGATAQTFIYPMEVMKTRL--------AVGKTGQYSGIYDCAKKILKHEGLGA 323
RF GS+AGA T +YP++++KTR+ VG+ Y +DC KK+L++EG
Sbjct: 329 RFTLGSVAGAVGATAVYPIDLVKTRMQNQRGSGSVVGEL-MYKNSFDCFKKVLRYEGFFG 387
Query: 324 FYKGYVPNLLGIIPYAGIDLAVYELLKSYWLDNFAKDSVN---PGVMVLLGCGALSSTCG 380
Y+G +P L+G+ P I L V + ++ D F + + P ++ GC S
Sbjct: 388 LYRGLIPQLIGVAPEKAIKLTVNDFVR----DKFTRRDGSVPLPAEVLAGGCAGGSQV-- 441
Query: 381 QLASYPLALVRTRMQAQAMLEGSPQLNMVGLFRRIISKEGIPGLYRGITPNFMKVLPAVG 440
+ + PL +V+ R+Q + P+++ + + R + GI GLY+G F++ +P
Sbjct: 442 -IFTNPLEIVKIRLQVAGEITTGPRVSALNVLRDL----GIFGLYKGAKACFLRDIPFSA 496
Query: 441 ISYVVYENMKQTL 453
I + VY + K L
Sbjct: 497 IYFPVYAHCKLLL 509
>gi|46094065 mitochondrial carrier family protein [Homo sapiens]
Length = 338
Score = 100 bits (249), Expect = 3e-21
Identities = 75/309 (24%), Positives = 136/309 (44%), Gaps = 41/309 (13%)
Query: 177 RQLLAGGIAGAVSRTSTAPLDRLKIMMQVHGSKSDKMNIF---------------GG--- 218
+Q+LA ++ PLD +KI +Q + K F GG
Sbjct: 17 QQMLASCTGAILTSVIVTPLDVVKIRLQAQNNPLPKGKCFVYSNGLMDHLCVCEEGGNKL 76
Query: 219 --------------FRQMVKEGGIRSLWRGNGTNVIKIAPETAVKFWAYEQYKKLLTEEG 264
F ++++ GI+SLW G ++ P T + F Y+Q LL +
Sbjct: 77 WYKKPGNFQGTLDAFFKIIRNEGIKSLWSGLPPTLVMAVPATVIYFTCYDQLSALLRSKL 136
Query: 265 QKIGTFERFISGSMAGATAQTFIYPMEVMKTRLAVGKTGQYSGIYDCAKKILKHEGLGAF 324
+ T ++G +A A T I P+E+++T++ K Y ++ K + +G +
Sbjct: 137 GENETCIPIVAGIVARFGAVTVISPLELIRTKMQ-SKKFSYVELHRFVSKKVSEDGWISL 195
Query: 325 YKGYVPNLLGIIPYAGIDLAVYELLKSYWLDNFAKDSVNPGVMVLLGCGALSSTCGQLAS 384
++G+ P +L +P++ + YE+LK + + P M+ GALS + +A+
Sbjct: 196 WRGWAPTVLRDVPFSAMYWYNYEILKKWLCEK--SGLYEPTFMINFTSGALSGSFAAVAT 253
Query: 385 YPLALVRTRMQAQAMLEGSPQLNMV------GLFRRIISKEGIPGLYRGITPNFMKVLPA 438
P +V+T+ Q Q S +++M + + I++K G GL+ G+ P +K+ PA
Sbjct: 254 LPFDVVKTQKQTQLWTYESHKISMPLHMSTWIIMKNIVAKNGFSGLFSGLIPRLIKIAPA 313
Query: 439 VGISYVVYE 447
I YE
Sbjct: 314 CAIMISTYE 322
Score = 63.9 bits (154), Expect = 3e-10
Identities = 51/188 (27%), Positives = 85/188 (45%), Gaps = 23/188 (12%)
Query: 184 IAGAVSR----TSTAPLDRLKIMMQVHGSKSDKMNIFGGFRQMVKEGGIRSLWRGNGTNV 239
+AG V+R T +PL+ ++ MQ K + + + V E G SLWRG V
Sbjct: 146 VAGIVARFGAVTVISPLELIRTKMQ--SKKFSYVELHRFVSKKVSEDGWISLWRGWAPTV 203
Query: 240 IKIAPETAVKFWAYEQYKKLLTEEGQKIGTFE-----RFISGSMAGATAQTFIYPMEVMK 294
++ P +A+ ++ YE KK L E K G +E F SG+++G+ A P +V+K
Sbjct: 204 LRDVPFSAMYWYNYEILKKWLCE---KSGLYEPTFMINFTSGALSGSFAAVATLPFDVVK 260
Query: 295 TRLAVG---------KTGQYSGIYDCAKKILKHEGLGAFYKGYVPNLLGIIPYAGIDLAV 345
T+ + + K I+ G + G +P L+ I P I ++
Sbjct: 261 TQKQTQLWTYESHKISMPLHMSTWIIMKNIVAKNGFSGLFSGLIPRLIKIAPACAIMIST 320
Query: 346 YELLKSYW 353
YE K+++
Sbjct: 321 YEFGKAFF 328
Score = 53.1 bits (126), Expect = 5e-07
Identities = 43/160 (26%), Positives = 75/160 (46%), Gaps = 22/160 (13%)
Query: 301 KTGQYSGIYDCAKKILKHEGLGAFYKGYVPNLLGIIPYAGIDLAVYE----LLKSYWLDN 356
K G + G D KI+++EG+ + + G P L+ +P I Y+ LL+S +N
Sbjct: 80 KPGNFQGTLDAFFKIIRNEGIKSLWSGLPPTLVMAVPATVIYFTCYDQLSALLRSKLGEN 139
Query: 357 FAKDSVNPGVMVLLGCGALSSTCGQLASYPLALVRTRMQAQAMLEGSPQLNMVGLFRRI- 415
+ G++ G + S PL L+RT+MQ S + + V L R +
Sbjct: 140 ETCIPIVAGIVARFGAVTVIS--------PLELIRTKMQ-------SKKFSYVELHRFVS 184
Query: 416 --ISKEGIPGLYRGITPNFMKVLPAVGISYVVYENMKQTL 453
+S++G L+RG P ++ +P + + YE +K+ L
Sbjct: 185 KKVSEDGWISLWRGWAPTVLRDVPFSAMYWYNYEILKKWL 224
>gi|58197562 solute carrier family 25, member 30 [Homo sapiens]
Length = 291
Score = 98.2 bits (243), Expect = 1e-20
Identities = 73/287 (25%), Positives = 124/287 (43%), Gaps = 15/287 (5%)
Query: 176 WRQLLAGGIAGAVSRTSTAPLDRLKIMMQVHGSKSDKMNIFGGFRQMV-------KEGGI 228
W+ + GG+A + T P+D K +Q+ G +D +R M+ +E G+
Sbjct: 6 WKPFVYGGLASITAECGTFPIDLTKTRLQIQGQTNDAKFKEIRYRGMLHALVRIGREEGL 65
Query: 229 RSLWRGNGTNVIKIAPETAVKFWAYEQYKKLLTEEGQKIGTFERFISGSMAGATAQTFIY 288
++L+ G +++ A +K Y+ K+L E + I G ++G + T
Sbjct: 66 KALYSGIAPAMLRQASYGTIKIGTYQSLKRLFIERPEDETLPINVICGILSGVISSTIAN 125
Query: 289 PMEVMKTRLAVGKTGQYSGIYDCAKKILKHEGLGAFYKGYVPNLLGIIPYAGIDLAVYEL 348
P +V+K R+ G+ I + EG +KG G++L VY++
Sbjct: 126 PTDVLKIRMQAQSNTIQGGMIGNFMNIYQQEGTRGLWKGVSLTAQRAAIVVGVELPVYDI 185
Query: 349 LKSYW-LDNFAKDSVNPGVMVLLGCGALSSTCGQLASYPLALVRTRMQAQAMLEGSPQLN 407
K + L D+V + CG G LAS P+ +VRTRM Q +L
Sbjct: 186 TKKHLILSGLMGDTVYTHFLSSFTCG----LAGALASNPVDVVRTRMMNQRVLRDGRCSG 241
Query: 408 MVGLFRRII---SKEGIPGLYRGITPNFMKVLPAVGISYVVYENMKQ 451
G ++ EG LY+G PN++++ P I +V YE +K+
Sbjct: 242 YTGTLDCLLQTWKNEGFFALYKGFWPNWLRLGPWNIIFFVTYEQLKK 288
Score = 83.6 bits (205), Expect = 3e-16
Identities = 55/189 (29%), Positives = 94/189 (49%), Gaps = 15/189 (7%)
Query: 273 FISGSMAGATAQTFIYPMEVMKTRLAV-GKTG-------QYSGIYDCAKKILKHEGLGAF 324
F+ G +A TA+ +P+++ KTRL + G+T +Y G+ +I + EGL A
Sbjct: 9 FVYGGLASITAECGTFPIDLTKTRLQIQGQTNDAKFKEIRYRGMLHALVRIGREEGLKAL 68
Query: 325 YKGYVPNLLGIIPYAGIDLAVYELLKSYWLDNFAKDSVNPGVMVLLGCGALSSTCGQLAS 384
Y G P +L Y I + Y+ LK +++ +++ V+ CG LS +
Sbjct: 69 YSGIAPAMLRQASYGTIKIGTYQSLKRLFIERPEDETLPINVI----CGILSGVISSTIA 124
Query: 385 YPLALVRTRMQAQAMLEGSPQLNMVGLFRRIISKEGIPGLYRGITPNFMKVLPAVGISYV 444
P +++ RMQAQ+ + Q M+G F I +EG GL++G++ + VG+
Sbjct: 125 NPTDVLKIRMQAQS---NTIQGGMIGNFMNIYQQEGTRGLWKGVSLTAQRAAIVVGVELP 181
Query: 445 VYENMKQTL 453
VY+ K+ L
Sbjct: 182 VYDITKKHL 190
>gi|82775373 solute carrier family 25, member 37 [Homo sapiens]
Length = 338
Score = 97.4 bits (241), Expect = 2e-20
Identities = 79/289 (27%), Positives = 128/289 (44%), Gaps = 24/289 (8%)
Query: 179 LLAGGIAGAVSRTSTAPLDRLKIMMQVHGS--KSDKMNIFGGFRQMVKEGGIRSLWRGNG 236
+ AG +AG + + P+D +K MQ K+ +I+G +++++ G RG
Sbjct: 49 MTAGAMAGILEHSVMYPVDSVKTRMQSLSPDPKAQYTSIYGALKKIMRTEGFWRPLRGVN 108
Query: 237 TNVIKIAPETAVKFWAYEQYKKLLTEEGQKIGT--FERFISGSMAGATAQTFIYPMEVMK 294
++ P A+ F YE K+ L + G I+GSMA + P EV+K
Sbjct: 109 VMIMGAGPAHAMYFACYENMKRTLNDVFHHQGNSHLANGIAGSMATLLHDAVMNPAEVVK 168
Query: 295 TRLAVGKTGQYSGIYDCAKKILKHEGLGAFYKGYVPNLLGIIPYAGIDLAVYELLKSYWL 354
RL + + S I C + + + EGLGAFY+ Y L IP+ I YE
Sbjct: 169 QRLQMYNSQHRSAI-SCIRTVWRTEGLGAFYRSYTTQLTMNIPFQSIHFITYE------- 220
Query: 355 DNFAKDSVNP----GVMVLLGCGALSSTCGQLASYPLALVRTRMQAQ-----AMLEGSPQ 405
F ++ VNP + G L+ A+ PL + +T + Q ++ S +
Sbjct: 221 --FLQEQVNPHRTYNPQSHIISGGLAGALAAAATTPLDVCKTLLNTQENVALSLANISGR 278
Query: 406 LN-MVGLFRRIISKEGIPGLYRGITPNFMKVLPAVGISYVVYENMKQTL 453
L+ M FR + G+ G ++GI + +P+ IS+ VYE K L
Sbjct: 279 LSGMANAFRTVYQLNGLAGYFKGIQARVIYQMPSTAISWSVYEFFKYFL 327
Score = 44.3 bits (103), Expect = 2e-04
Identities = 27/92 (29%), Positives = 48/92 (52%), Gaps = 8/92 (8%)
Query: 179 LLAGGIAGAVSRTSTAPLDRLKIMMQVHGSKSDKM-NIFG-------GFRQMVKEGGIRS 230
+++GG+AGA++ +T PLD K ++ + + + NI G FR + + G+
Sbjct: 238 IISGGLAGALAAAATTPLDVCKTLLNTQENVALSLANISGRLSGMANAFRTVYQLNGLAG 297
Query: 231 LWRGNGTNVIKIAPETAVKFWAYEQYKKLLTE 262
++G VI P TA+ + YE +K LT+
Sbjct: 298 YFKGIQARVIYQMPSTAISWSVYEFFKYFLTK 329
>gi|7706306 solute carrier family 25, member 39 isoform b [Homo
sapiens]
Length = 351
Score = 97.4 bits (241), Expect = 2e-20
Identities = 65/236 (27%), Positives = 112/236 (47%), Gaps = 11/236 (4%)
Query: 219 FRQMVKEGGIRSLWRGNGTNVIKIAPETAVKFWAYEQYKKLLTEEGQKIGTFERFISGSM 278
F ++V+ G R+LW G ++ P TA+ F AY+Q K L + ++G++
Sbjct: 103 FVKIVRHEGTRTLWSGLPATLVMTVPATAIYFTAYDQLKAFLCGRALTSDLYAPMVAGAL 162
Query: 279 AGATAQTFIYPMEVMKTRLAVGKTGQYSGIYDCAKKILKHEGLGAFYKGYVPNLLGIIPY 338
A T I P+E+M+T+L Y + C + + G + + G+ P L +P+
Sbjct: 163 ARLGTVTVISPLELMRTKLQAQHV-SYRELGACVRTAVAQGGWRSLWLGWGPTALRDVPF 221
Query: 339 AGIDLAVYELLKSYWLDNF-AKDSVNPGVMVLLGCGALSSTCGQLASYPLALVRTRMQAQ 397
+ + YEL+KS WL+ F KD + G+ + G +S T + + P +V+T+ Q
Sbjct: 222 SALYWFNYELVKS-WLNGFRPKDQTSVGMSFV--AGGISGTVAAVLTLPFDVVKTQRQVA 278
Query: 398 AMLEGSPQLNMVG------LFRRIISKEGIPGLYRGITPNFMKVLPAVGISYVVYE 447
+ ++N + L RRI ++ G GL+ G P +K P+ I YE
Sbjct: 279 LGAMEAVRVNPLHVDSTWLLLRRIRAESGTKGLFAGFLPRIIKAAPSCAIMISTYE 334
Score = 59.3 bits (142), Expect = 7e-09
Identities = 47/190 (24%), Positives = 84/190 (44%), Gaps = 17/190 (8%)
Query: 179 LLAGGIAGAVSRTST----APLDRLKIMMQVHGSKSDKMNIFGGFRQMVKEGGIRSLWRG 234
L A +AGA++R T +PL+ ++ +Q ++ R V +GG RSLW G
Sbjct: 153 LYAPMVAGALARLGTVTVISPLELMRTKLQAQHVSYRELGAC--VRTAVAQGGWRSLWLG 210
Query: 235 NGTNVIKIAPETAVKFWAYEQYKKLLTEEGQKIGTFE--RFISGSMAGATAQTFIYPMEV 292
G ++ P +A+ ++ YE K L K T F++G ++G A P +V
Sbjct: 211 WGPTALRDVPFSALYWFNYELVKSWLNGFRPKDQTSVGMSFVAGGISGTVAAVLTLPFDV 270
Query: 293 MKTRLAVGKTGQYS---------GIYDCAKKILKHEGLGAFYKGYVPNLLGIIPYAGIDL 343
+KT+ V + + ++I G + G++P ++ P I +
Sbjct: 271 VKTQRQVALGAMEAVRVNPLHVDSTWLLLRRIRAESGTKGLFAGFLPRIIKAAPSCAIMI 330
Query: 344 AVYELLKSYW 353
+ YE KS++
Sbjct: 331 STYEFGKSFF 340
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.137 0.406
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 15,686,342
Number of Sequences: 37866
Number of extensions: 667250
Number of successful extensions: 3014
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 157
Number of HSP's successfully gapped in prelim test: 88
Number of HSP's that attempted gapping in prelim test: 1876
Number of HSP's gapped (non-prelim): 644
length of query: 458
length of database: 18,247,518
effective HSP length: 106
effective length of query: 352
effective length of database: 14,233,722
effective search space: 5010270144
effective search space used: 5010270144
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.