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Search of human proteins with 46397377
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|46397377 chromosome 14 open reading frame 68 [Homo sapiens]
(308 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|46397377 chromosome 14 open reading frame 68 [Homo sapiens] 637 0.0
gi|116235462 solute carrier family 25, member 45 isoform a [Homo... 250 1e-66
gi|116235466 solute carrier family 25, member 45 isoform b [Homo... 208 4e-54
gi|86198310 solute carrier family 25, member 29 [Homo sapiens] 192 4e-49
gi|4557403 carnitine/acylcarnitine translocase [Homo sapiens] 152 5e-37
gi|7657585 mitochondrial ornithine transporter 1 [Homo sapiens] 119 4e-27
gi|13994341 solute carrier family 25 member 2 [Homo sapiens] 118 8e-27
gi|13375983 mitochondrial glutamate carrier 1 [Homo sapiens] 118 8e-27
gi|21361103 solute carrier family 25, member 12 [Homo sapiens] 116 3e-26
gi|7657581 solute carrier family 25, member 13 isoform 2 [Homo s... 115 4e-26
gi|237649019 solute carrier family 25, member 13 isoform 1 [Homo... 115 4e-26
gi|21389315 solute carrier family 25 (mitochondrial carrier; cit... 111 7e-25
gi|223468576 mitochondrial carrier protein-like [Homo sapiens] 107 1e-23
gi|13259541 uncoupling protein 2 [Homo sapiens] 105 5e-23
gi|11225256 uncoupling protein 1 [Homo sapiens] 102 3e-22
gi|4507807 uncoupling protein 3 isoform UCP3L [Homo sapiens] 100 1e-21
gi|13899342 solute carrier [Homo sapiens] 92 4e-19
gi|13259546 uncoupling protein 3 isoform UCP3S [Homo sapiens] 90 3e-18
gi|21314739 solute carrier family 25, member 32 [Homo sapiens] 86 3e-17
gi|186928856 solute carrier family 25, member 19 [Homo sapiens] 84 1e-16
gi|186928860 solute carrier family 25, member 19 [Homo sapiens] 84 1e-16
gi|186928858 solute carrier family 25, member 19 [Homo sapiens] 84 1e-16
gi|46409330 solute carrier family 25, member 34 [Homo sapiens] 82 8e-16
gi|20149598 solute carrier family 25 (mitochondrial carrier; dic... 80 3e-15
gi|13449279 solute carrier family 25 (mitochondrial oxodicarboxy... 77 1e-14
gi|27544933 solute carrier family 25, member 16 [Homo sapiens] 77 1e-14
gi|82775373 solute carrier family 25, member 37 [Homo sapiens] 76 3e-14
gi|157388989 solute carrier family 25, member 36 isoform a [Homo... 75 1e-13
gi|58197562 solute carrier family 25, member 30 [Homo sapiens] 74 1e-13
gi|21361114 solute carrier family 25 (mitochondrial carrier; oxo... 73 4e-13
>gi|46397377 chromosome 14 open reading frame 68 [Homo sapiens]
Length = 308
Score = 637 bits (1643), Expect = 0.0
Identities = 308/308 (100%), Positives = 308/308 (100%)
Query: 1 MDFVAGAIGGVCGVAVGYPLDTVKVRIQTEPKYTGIWHCVRDTYHRERVWGFYRGLSLPV 60
MDFVAGAIGGVCGVAVGYPLDTVKVRIQTEPKYTGIWHCVRDTYHRERVWGFYRGLSLPV
Sbjct: 1 MDFVAGAIGGVCGVAVGYPLDTVKVRIQTEPKYTGIWHCVRDTYHRERVWGFYRGLSLPV 60
Query: 61 CTVSLVSSVSFGTYRHCLAHICRLRYGNPDAKPTKADITLSGCASGLVRVFLTSPTEVAK 120
CTVSLVSSVSFGTYRHCLAHICRLRYGNPDAKPTKADITLSGCASGLVRVFLTSPTEVAK
Sbjct: 61 CTVSLVSSVSFGTYRHCLAHICRLRYGNPDAKPTKADITLSGCASGLVRVFLTSPTEVAK 120
Query: 121 VRLQTQTQAQKQQRRLSASGPLAVPPMCPVPPACPEPKYRGPLHCLATVAREEGLCGLYK 180
VRLQTQTQAQKQQRRLSASGPLAVPPMCPVPPACPEPKYRGPLHCLATVAREEGLCGLYK
Sbjct: 121 VRLQTQTQAQKQQRRLSASGPLAVPPMCPVPPACPEPKYRGPLHCLATVAREEGLCGLYK 180
Query: 181 GSSALVLRDGHSFATYFLSYAVLCEWLSPAGHSRPDVPGVLVAGGCAGVLAWAVATPMDV 240
GSSALVLRDGHSFATYFLSYAVLCEWLSPAGHSRPDVPGVLVAGGCAGVLAWAVATPMDV
Sbjct: 181 GSSALVLRDGHSFATYFLSYAVLCEWLSPAGHSRPDVPGVLVAGGCAGVLAWAVATPMDV 240
Query: 241 IKSRLQADGQGQRRYRGLLHCMVTSVREEGPRVLFKGLVLNCCRAFPVNMVVFVAYEAVL 300
IKSRLQADGQGQRRYRGLLHCMVTSVREEGPRVLFKGLVLNCCRAFPVNMVVFVAYEAVL
Sbjct: 241 IKSRLQADGQGQRRYRGLLHCMVTSVREEGPRVLFKGLVLNCCRAFPVNMVVFVAYEAVL 300
Query: 301 RLARGLLT 308
RLARGLLT
Sbjct: 301 RLARGLLT 308
>gi|116235462 solute carrier family 25, member 45 isoform a [Homo
sapiens]
Length = 288
Score = 250 bits (639), Expect = 1e-66
Identities = 127/301 (42%), Positives = 187/301 (62%), Gaps = 21/301 (6%)
Query: 2 DFVAGAIGGVCGVAVGYPLDTVKVRIQTEPKYTGIWHCVRDTYHRERVWGFYRGLSLPVC 61
+FVAG I G G+ +G+P DTVKVR+QT+ Y GI C+ Y E + GF++G+S P+
Sbjct: 5 EFVAGWISGALGLVLGHPFDTVKVRLQTQTTYRGIVDCMVKIYRHESLLGFFKGMSFPIA 64
Query: 62 TVSLVSSVSFGTYRHCLAHICRLRYGNPDAKPTK-ADITLSGCASGLVRVFLTSPTEVAK 120
++++V+SV FG Y + L + + A+P I L+GC G ++ + +P ++ K
Sbjct: 65 SIAVVNSVLFGVYSNTLLVLTATSHQERRAQPPSYMHIFLAGCTGGFLQAYCLAPFDLIK 124
Query: 121 VRLQTQTQAQKQQRRLSASGPLAVPPMCPVPPACPEPKYRGPLHCLATVAREEGLCGLYK 180
VRLQ QT+ + Q P P P+Y+GP+HC A++ REEG GL++
Sbjct: 125 VRLQNQTEPRAQ-------------------PGSPPPRYQGPVHCAASIFREEGPRGLFR 165
Query: 181 GSSALVLRDGHSFATYFLSYAVLCEWLSPAGHSRPDVPGVLVAGGCAGVLAWAVATPMDV 240
G+ AL LRD + YF++Y LC +P G + P VLVAGG AG+ +W ATP+D+
Sbjct: 166 GAWALTLRDTPTVGIYFITYEGLCRQYTPEGQN-PSSATVLVAGGFAGIASWVAATPLDM 224
Query: 241 IKSRLQADGQGQRRYRGLLHCMVTSVREEGPRVLFKGLVLNCCRAFPVNMVVFVAYEAVL 300
IKSR+Q DG +R Y+G+L CMV+S+R+EG V F+G+ +N RAFPVN V F++YE +L
Sbjct: 225 IKSRMQMDGLRRRVYQGMLDCMVSSIRQEGLGVFFRGVTINSARAFPVNAVTFLSYEYLL 284
Query: 301 R 301
R
Sbjct: 285 R 285
>gi|116235466 solute carrier family 25, member 45 isoform b [Homo
sapiens]
Length = 246
Score = 208 bits (530), Expect = 4e-54
Identities = 106/259 (40%), Positives = 159/259 (61%), Gaps = 21/259 (8%)
Query: 44 YHRERVWGFYRGLSLPVCTVSLVSSVSFGTYRHCLAHICRLRYGNPDAKPTK-ADITLSG 102
Y E + GF++G+S P+ ++++V+SV FG Y + L + + A+P I L+G
Sbjct: 5 YRHESLLGFFKGMSFPIASIAVVNSVLFGVYSNTLLVLTATSHQERRAQPPSYMHIFLAG 64
Query: 103 CASGLVRVFLTSPTEVAKVRLQTQTQAQKQQRRLSASGPLAVPPMCPVPPACPEPKYRGP 162
C G ++ + +P ++ KVRLQ QT+ + Q P P P+Y+GP
Sbjct: 65 CTGGFLQAYCLAPFDLIKVRLQNQTEPRAQ-------------------PGSPPPRYQGP 105
Query: 163 LHCLATVAREEGLCGLYKGSSALVLRDGHSFATYFLSYAVLCEWLSPAGHSRPDVPGVLV 222
+HC A++ REEG GL++G+ AL LRD + YF++Y LC +P G + P VLV
Sbjct: 106 VHCAASIFREEGPRGLFRGAWALTLRDTPTVGIYFITYEGLCRQYTPEGQN-PSSATVLV 164
Query: 223 AGGCAGVLAWAVATPMDVIKSRLQADGQGQRRYRGLLHCMVTSVREEGPRVLFKGLVLNC 282
AGG AG+ +W ATP+D+IKSR+Q DG +R Y+G+L CMV+S+R+EG V F+G+ +N
Sbjct: 165 AGGFAGIASWVAATPLDMIKSRMQMDGLRRRVYQGMLDCMVSSIRQEGLGVFFRGVTINS 224
Query: 283 CRAFPVNMVVFVAYEAVLR 301
RAFPVN V F++YE +LR
Sbjct: 225 ARAFPVNAVTFLSYEYLLR 243
Score = 60.8 bits (146), Expect = 1e-09
Identities = 53/215 (24%), Positives = 85/215 (39%), Gaps = 42/215 (19%)
Query: 3 FVAGAIGGVCGVAVGYPLDTVKVRIQTE-----------PKYTGIWHCVRDTYHRERVWG 51
F+AG GG P D +KVR+Q + P+Y G HC + E G
Sbjct: 61 FLAGCTGGFLQAYCLAPFDLIKVRLQNQTEPRAQPGSPPPRYQGPVHCAASIFREEGPRG 120
Query: 52 FYRGLSLPVCTVSLVSSVSFGTYRHCLAHICRLRYGNPDAKPTKADITLSGCASGLVRVF 111
+RG ++L + + G Y +CR +Y P+ A + ++G +G+
Sbjct: 121 LFRG----AWALTLRDTPTVGIYFITYEGLCR-QYTPEGQNPSSATVLVAGGFAGIASWV 175
Query: 112 LTSPTEVAKVRLQTQTQAQKQQRRLSASGPLAVPPMCPVPPACPEPKYRGPLHCLATVAR 171
+P ++ K R+ Q +RR+ Y+G L C+ + R
Sbjct: 176 AATPLDMIKSRM----QMDGLRRRV----------------------YQGMLDCMVSSIR 209
Query: 172 EEGLCGLYKGSSALVLRDGHSFATYFLSYAVLCEW 206
+EGL ++G + R A FLSY L W
Sbjct: 210 QEGLGVFFRGVTINSARAFPVNAVTFLSYEYLLRW 244
>gi|86198310 solute carrier family 25, member 29 [Homo sapiens]
Length = 303
Score = 192 bits (487), Expect = 4e-49
Identities = 118/310 (38%), Positives = 164/310 (52%), Gaps = 39/310 (12%)
Query: 1 MDFVAGAIGGVCGVAVGYPLDTVKVRIQTE----PKYTGIWHCVRDTYHRERVWGFYRGL 56
+DF+AG GGV GV VG+P DTVKVR+Q + P+Y G HC + +E V G Y+GL
Sbjct: 3 LDFLAGCAGGVAGVLVGHPFDTVKVRLQVQSVEKPQYRGTLHCFKSIIKQESVLGLYKGL 62
Query: 57 SLPVCTVSLVSSVSFGTYRHCLAHICRLRYGNPDAKPTKADITLSGCASGLVRVFLTSPT 116
P+ ++ ++++ FG + L L + +P + L+G A+G ++ + P
Sbjct: 63 GSPLMGLTFINALVFGVQGNTLR---ALGHDSP------LNQFLAGAAAGAIQCVICCPM 113
Query: 117 EVAKVRLQTQTQAQKQQRRLSASGPLAVPPMCPVPPACPEPKYRGPLHCLATVAREEGLC 176
E+AK RLQ Q A P Y+G L CLA + EGL
Sbjct: 114 ELAKTRLQLQD-------------------------AGPARTYKGSLDCLAQIYGHEGLR 148
Query: 177 GLYKGSSALVLRDGHSFATYFLSYAVLCEWLSPAGHSRPDVPGVLVAGGCAGVLAWAVAT 236
G+ +G + +LR+ SF YFL+Y L L R VP +L+AGG +G+++W
Sbjct: 149 GVNRGMVSTLLRETPSFGVYFLTYDALTRALGCEPGDRLLVPKLLLAGGTSGIVSWLSTY 208
Query: 237 PMDVIKSRLQADG-QGQRRYRGLLHCMVTSVREEGPRVLFKGLVLNCCRAFPVNMVVFVA 295
P+DV+KSRLQADG +G RYRG+L C+ S R EG RV +GL RAFPVN F
Sbjct: 209 PVDVVKSRLQADGLRGAPRYRGILDCVHQSYRAEGWRVFTRGLASTLLRAFPVNAATFAT 268
Query: 296 YEAVLRLARG 305
VL ARG
Sbjct: 269 VTVVLTYARG 278
>gi|4557403 carnitine/acylcarnitine translocase [Homo sapiens]
Length = 301
Score = 152 bits (383), Expect = 5e-37
Identities = 104/310 (33%), Positives = 154/310 (49%), Gaps = 40/310 (12%)
Query: 2 DFVAGAIGGVCGVAVGYPLDTVKVRIQTE--------PKYTGIWHCVRDTYHRERVWGFY 53
+ +AG GGVC V VG+PLDTVKVR+QT+ P Y+G + C R T RE + G Y
Sbjct: 13 NLLAGGFGGVCLVFVGHPLDTVKVRLQTQPPSLPGQPPMYSGTFDCFRKTLFREGITGLY 72
Query: 54 RGLSLPVCTVSLVSSVSFGTYRHCLAHICRLRYGNPDAKPTKADITLSGCASGLVRVFLT 113
RG++ P+ V+ + +V F + L +L+ +P+ + + +G SG+ +
Sbjct: 73 RGMAAPIIGVTPMFAVCF--FGFGLGK--KLQQKHPEDVLSYPQLFAAGMLSGVFTTGIM 128
Query: 114 SPTEVAKVRLQTQTQAQKQQRRLSASGPLAVPPMCPVPPACPEPKYRGPLHCLATVAREE 173
+P E K LQ Q ++SG E KY G L C + +E
Sbjct: 129 TPGERIKCLLQIQ----------ASSG---------------ESKYTGTLDCAKKLYQEF 163
Query: 174 GLCGLYKGSSALVLRDGHSFATYFLSYAVLCEWLSPAGH--SRPDVPGVLVAGGCAGVLA 231
G+ G+YKG+ ++RD + YF++Y L +P G S P +LVAGG AG+
Sbjct: 164 GIRGIYKGTVLTLMRDVPASGMYFMTYEWLKNIFTPEGKRVSELSAPRILVAGGIAGIFN 223
Query: 232 WAVATPMDVIKSRLQADGQGQRRYRGLLHCMVTSVREEGPRVLFKGLVLNCCRAFPVNMV 291
WAVA P DV+KSR Q G + G + +R+EG L+KG RAFP N
Sbjct: 224 WAVAIPPDVLKSRFQTAPPG-KYPNGFRDVLRELIRDEGVTSLYKGFNAVMIRAFPANAA 282
Query: 292 VFVAYEAVLR 301
F+ +E ++
Sbjct: 283 CFLGFEVAMK 292
Score = 53.1 bits (126), Expect = 3e-07
Identities = 54/212 (25%), Positives = 86/212 (40%), Gaps = 36/212 (16%)
Query: 3 FVAGAIGGVCGVAVGYPLDTVKVRIQT-----EPKYTGIWHCVRDTYHRERVWGFYRGLS 57
F AG + GV + P + +K +Q E KYTG C + Y + G Y+G
Sbjct: 114 FAAGMLSGVFTTGIMTPGERIKCLLQIQASSGESKYTGTLDCAKKLYQEFGIRGIYKGTV 173
Query: 58 LPVCTVSLVSSVSFGTYRHCLAHICRLRYGNPDAKPTKADITLSGCASGLVRVFLTSPTE 117
L + S + F TY L +I G ++ + I ++G +G+ + P +
Sbjct: 174 LTLMRDVPASGMYFMTYEW-LKNIFTPE-GKRVSELSAPRILVAGGIAGIFNWAVAIPPD 231
Query: 118 VAKVRLQTQTQAQKQQRRLSASGPLAVPPMCPVPPACPEPKY-RGPLHCLATVAREEGLC 176
V K R QT P KY G L + R+EG+
Sbjct: 232 VLKSRFQT----------------------------APPGKYPNGFRDVLRELIRDEGVT 263
Query: 177 GLYKGSSALVLRDGHSFATYFLSYAVLCEWLS 208
LYKG +A+++R + A FL + V ++L+
Sbjct: 264 SLYKGFNAVMIRAFPANAACFLGFEVAMKFLN 295
>gi|7657585 mitochondrial ornithine transporter 1 [Homo sapiens]
Length = 301
Score = 119 bits (297), Expect = 4e-27
Identities = 85/300 (28%), Positives = 137/300 (45%), Gaps = 25/300 (8%)
Query: 1 MDFVAGAIGGVCGVAVGYPLDTVKVRIQTEPK-YTGIWHCVRDTYHRERVWGFYRGLSLP 59
+D AGA GG V G P DT+KV++QT P Y G+ C TY + GFY+G S
Sbjct: 11 IDLTAGAAGGTACVLTGQPFDTMKVKMQTFPDLYRGLTDCCLKTYSQVGFRGFYKGTSPA 70
Query: 60 VCTVSLVSSVSFGTYRHCLAHICRLRYGNPDAKPTKADITLSGCASGLVRVFLTSPTEVA 119
+ +SV F Y C + ++ + AK + +G + + PTE+
Sbjct: 71 LIANIAENSVLFMCYGFCQQVVRKVAGLDKQAKLSDLQNAAAGSFASAFAALVLCPTELV 130
Query: 120 KVRLQTQTQAQKQQRRLSASGPLAVPPMCPVPPACPEPKYRGPLHCLATVAREEGLCGLY 179
K RLQT + + SG +A + ++ R++G G Y
Sbjct: 131 KCRLQTMYE-------METSGKIA-------------KSQNTVWSVIKSILRKDGPLGFY 170
Query: 180 KGSSALVLRDGHSFATYFLSYAVLCEWLSPAGHSRPDVPGV--LVAGGCAGVLAWAVATP 237
G S+ +LR+ + +F Y + + + +G S+ ++ V +++GG G+ W P
Sbjct: 171 HGLSSTLLREVPGYFFFFGGYELSRSFFA-SGRSKDELGPVPLMLSGGVGGICLWLAVYP 229
Query: 238 MDVIKSRLQADGQGQRRYRGLLHCMVTSVREEGPRVLFKGLVLNCCRAFPVNMVVFVAYE 297
+D IKSR+Q ++ G + + V+ EG L+ GL RAFP N +F+AYE
Sbjct: 230 VDCIKSRIQVLSMSGKQ-AGFIRTFINVVKNEGITALYSGLKPTMIRAFPANGALFLAYE 288
>gi|13994341 solute carrier family 25 member 2 [Homo sapiens]
Length = 301
Score = 118 bits (295), Expect = 8e-27
Identities = 85/300 (28%), Positives = 138/300 (46%), Gaps = 25/300 (8%)
Query: 1 MDFVAGAIGGVCGVAVGYPLDTVKVRIQTEPK-YTGIWHCVRDTYHRERVWGFYRGLSLP 59
+D AGA GG V G P DT+KV++QT P Y G+ C TY + + GFY+G
Sbjct: 11 IDLTAGAAGGTACVLTGQPFDTIKVKMQTFPDLYKGLTDCFLKTYAQVGLRGFYKGTGPA 70
Query: 60 VCTVSLVSSVSFGTYRHCLAHICRLRYGNPDAKPTKADITLSGCASGLVRVFLTSPTEVA 119
+ +SV F Y C + ++ + AK + +G + PTE+
Sbjct: 71 LMAYVAENSVLFMCYGFCQQFVRKVAGMDKQAKLSDLQTAAAGSFASAFAALALCPTELV 130
Query: 120 KVRLQTQTQAQKQQRRLSASGPLAVPPMCPVPPACPEPKYRGPLHCLATVAREEGLCGLY 179
K RLQT + + SG +A + + + +++G G Y
Sbjct: 131 KCRLQTMYE-------MEMSGKIA-------------KSHNTIWSVVKGILKKDGPLGFY 170
Query: 180 KGSSALVLRDGHSFATYFLSYAVLCEWLSPAGHSRPDVPGV--LVAGGCAGVLAWAVATP 237
G S+ +L++ + +F Y + + + +G S+ ++ V +++GG AG+ W V P
Sbjct: 171 HGLSSTLLQEVPGYFFFFGGYELSRSFFA-SGRSKDELGPVHLMLSGGVAGICLWLVVFP 229
Query: 238 MDVIKSRLQADGQGQRRYRGLLHCMVTSVREEGPRVLFKGLVLNCCRAFPVNMVVFVAYE 297
+D IKSR+Q + G + +++ VR EG L+ GL RA P N +FVAYE
Sbjct: 230 VDCIKSRIQVLSM-YGKQAGFIGTLLSVVRNEGIVALYSGLKATMIRAIPANGALFVAYE 288
>gi|13375983 mitochondrial glutamate carrier 1 [Homo sapiens]
Length = 323
Score = 118 bits (295), Expect = 8e-27
Identities = 92/316 (29%), Positives = 138/316 (43%), Gaps = 25/316 (7%)
Query: 4 VAGAIGGVCGVAVGYPLDTVKVRIQTEPK----YTGIWHCVRDTYHRERVWGFYRGLSLP 59
+ G I G+ GV +P+D K R+Q + YT + C+ T E +G YRG ++
Sbjct: 13 INGGIAGLIGVTCVFPIDLAKTRLQNQQNGQRVYTSMSDCLIKTVRSEGYFGMYRGAAVN 72
Query: 60 VCTVSLVSSVSFGT---YRHCLAHICRLRYGNPDAKPTKADITLSGCASGLVRVFLTSPT 116
+ V+ ++ +RH L+ K T L+GC +G +V +T+P
Sbjct: 73 LTLVTPEKAIKLAANDFFRHQLS--------KDGQKLTLLKEMLAGCGAGTCQVIVTTPM 124
Query: 117 EVAKVRLQTQTQAQKQQRRLSASGPLAVPPMCPVP---PACPEPKYRGPLHCLATVAREE 173
E+ K++LQ + Q++ L+A G L+ PA P P + R
Sbjct: 125 EMLKIQLQDAGRIAAQRKILAAQGQLSAQGGAQPSVEAPAAPRPT---ATQLTRDLLRSR 181
Query: 174 GLCGLYKGSSALVLRDGHSFATYFLSYAVLCEWLSPAGHSRPDVPGVLVAGGCAGVLAWA 233
G+ GLYKG A +LRD YF +A L + PA + +AG AG A
Sbjct: 182 GIAGLYKGLGATLLRDVPFSVVYFPLFANLNQLGRPASEEKSPFYVSFLAGCVAGSAAAV 241
Query: 234 VATPMDVIKSRLQA--DGQGQRRYRGLLHCMVTSVREEGPRVLFKGLVLNCCRAFPVNMV 291
P DV+K+RLQ+ G + Y G+L C +R EGP KG P+ +
Sbjct: 242 AVNPCDVVKTRLQSLQRGVNEDTYSGILDCARKILRHEGPSAFLKGAYCRALVIAPLFGI 301
Query: 292 VFVAYEAVLRLARGLL 307
V Y L +A LL
Sbjct: 302 AQVVY--FLGIAESLL 315
Score = 52.4 bits (124), Expect = 5e-07
Identities = 25/79 (31%), Positives = 41/79 (51%)
Query: 217 VPGVLVAGGCAGVLAWAVATPMDVIKSRLQADGQGQRRYRGLLHCMVTSVREEGPRVLFK 276
+P L+ GG AG++ P+D+ K+RLQ GQR Y + C++ +VR EG +++
Sbjct: 8 LPAKLINGGIAGLIGVTCVFPIDLAKTRLQNQQNGQRVYTSMSDCLIKTVRSEGYFGMYR 67
Query: 277 GLVLNCCRAFPVNMVVFVA 295
G +N P + A
Sbjct: 68 GAAVNLTLVTPEKAIKLAA 86
Score = 34.3 bits (77), Expect = 0.14
Identities = 19/61 (31%), Positives = 26/61 (42%), Gaps = 6/61 (9%)
Query: 1 MDFVAGAIGGVCGVAVGYPLDTVKVRIQT------EPKYTGIWHCVRDTYHRERVWGFYR 54
+ F+AG + G P D VK R+Q+ E Y+GI C R E F +
Sbjct: 227 VSFLAGCVAGSAAAVAVNPCDVVKTRLQSLQRGVNEDTYSGILDCARKILRHEGPSAFLK 286
Query: 55 G 55
G
Sbjct: 287 G 287
>gi|21361103 solute carrier family 25, member 12 [Homo sapiens]
Length = 678
Score = 116 bits (290), Expect = 3e-26
Identities = 94/310 (30%), Positives = 132/310 (42%), Gaps = 47/310 (15%)
Query: 3 FVAGAIGGVCGVAVGYPLDTVKVRIQT---------EPKYTGIWHCVRDTYHRERVWGFY 53
F G++ G G YP+D VK R+Q E Y + C + E +G Y
Sbjct: 330 FTLGSVAGAVGATAVYPIDLVKTRMQNQRGSGSVVGELMYKNSFDCFKKVLRYEGFFGLY 389
Query: 54 RGLSLPVCTVSLVSSVSFGTYRHCLAHICRLRYGNPDAK-PTKADITLSGCASGLVRVFL 112
RGL + V+ ++ + R ++ D P A++ GCA G +V
Sbjct: 390 RGLIPQLIGVAPEKAIKL-----TVNDFVRDKFTRRDGSVPLPAEVLAGGCAGGS-QVIF 443
Query: 113 TSPTEVAKVRLQTQTQAQKQQRRLSASGPLAVPPMCPVPPACPEPKYRGPLHCLATVARE 172
T+P E+ K+RLQ +G + GP V R+
Sbjct: 444 TNPLEIVKIRLQV-------------AGEITT----------------GPRVSALNVLRD 474
Query: 173 EGLCGLYKGSSALVLRDGHSFATYFLSYAVLCEWLSPAGHSRPDVPGVLVAGGCAGVLAW 232
G+ GLYKG+ A LRD A YF YA C+ L + +L AG AGV A
Sbjct: 475 LGIFGLYKGAKACFLRDIPFSAIYFPVYAH-CKLLLADENGHVGGLNLLAAGAMAGVPAA 533
Query: 233 AVATPMDVIKSRLQADGQ-GQRRYRGLLHCMVTSVREEGPRVLFKGLVLNCCRAFPVNMV 291
++ TP DVIK+RLQ + GQ Y G++ C +REEGP +KG R+ P V
Sbjct: 534 SLVTPADVIKTRLQVAARAGQTTYSGVIDCFRKILREEGPSAFWKGTAARVFRSSPQFGV 593
Query: 292 VFVAYEAVLR 301
V YE + R
Sbjct: 594 TLVTYELLQR 603
Score = 60.8 bits (146), Expect = 1e-09
Identities = 53/223 (23%), Positives = 88/223 (39%), Gaps = 48/223 (21%)
Query: 2 DFVAGAIGGVCGVAVGYPLDTVKVRIQ------TEPKYTGIWHCVRDTYHRERVWGFYRG 55
+ +AG G V PL+ VK+R+Q T P+ + + + +RD ++G Y+G
Sbjct: 429 EVLAGGCAGGSQVIFTNPLEIVKIRLQVAGEITTGPRVSAL-NVLRDL----GIFGLYKG 483
Query: 56 LSLPVCTVSLVSSVSFGTYRHCLAHICRLRYGNPDAKPTKADITLSGCASGLVRVFLTSP 115
S++ F Y HC +L + + ++ +G +G+ L +P
Sbjct: 484 AKACFLRDIPFSAIYFPVYAHC-----KLLLADENGHVGGLNLLAAGAMAGVPAASLVTP 538
Query: 116 TEVAKVRLQTQTQAQKQQRRLSASGPLAVPPMCPVPPACPEPKYRGPLHCLATVAREEGL 175
+V K RLQ +A + Y G + C + REEG
Sbjct: 539 ADVIKTRLQVAARAG-------------------------QTTYSGVIDCFRKILREEGP 573
Query: 176 CGLYKGSSALVLRDGHSFATYFLSYAVLCEW-------LSPAG 211
+KG++A V R F ++Y +L W L PAG
Sbjct: 574 SAFWKGTAARVFRSSPQFGVTLVTYELLQRWFYIDFGGLKPAG 616
>gi|7657581 solute carrier family 25, member 13 isoform 2 [Homo
sapiens]
Length = 675
Score = 115 bits (289), Expect = 4e-26
Identities = 94/311 (30%), Positives = 137/311 (44%), Gaps = 49/311 (15%)
Query: 3 FVAGAIGGVCGVAVGYPLDTVKVRIQT---------EPKYTGIWHCVRDTYHRERVWGFY 53
F G++ G G YP+D VK R+Q E Y + C + E +G Y
Sbjct: 332 FGLGSVAGAVGATAVYPIDLVKTRMQNQRSTGSFVGELMYKNSFDCFKKVLRYEGFFGLY 391
Query: 54 RGLSLPVCTVSLVSSVSFGTYRHCLAHICRLRYGNPDAK-PTKADITLSGCASGLVRVFL 112
RGL + V+ ++ + R ++ + D P A+I GCA G +V
Sbjct: 392 RGLLPQLLGVAPEKAIKL-----TVNDFVRDKFMHKDGSVPLAAEILAGGCAGGS-QVIF 445
Query: 113 TSPTEVAKVRLQTQTQAQKQQRRLSASGPLAVPPMCPVPPACPEPKYRGPLHCLATVARE 172
T+P E+ K+RLQ +G + GP +V R+
Sbjct: 446 TNPLEIVKIRLQV-------------AGEITT----------------GPRVSALSVVRD 476
Query: 173 EGLCGLYKGSSALVLRDGHSFATYFLSYA-VLCEWLSPAGHSRPDVPGVLVAGGCAGVLA 231
G G+YKG+ A LRD A YF YA V + + G P +L+AG AG+ A
Sbjct: 477 LGFFGIYKGAKACFLRDIPFSAIYFPCYAHVKASFANEDGQVSPG--SLLLAGAIAGMPA 534
Query: 232 WAVATPMDVIKSRLQADGQ-GQRRYRGLLHCMVTSVREEGPRVLFKGLVLNCCRAFPVNM 290
++ TP DVIK+RLQ + GQ Y G++ C +REEGP+ L+KG R+ P
Sbjct: 535 ASLVTPADVIKTRLQVAARAGQTTYSGVIDCFRKILREEGPKALWKGAGARVFRSSPQFG 594
Query: 291 VVFVAYEAVLR 301
V + YE + R
Sbjct: 595 VTLLTYELLQR 605
Score = 65.5 bits (158), Expect = 6e-11
Identities = 54/212 (25%), Positives = 85/212 (40%), Gaps = 43/212 (20%)
Query: 2 DFVAGAIGGVCGVAVGYPLDTVKVRIQ------TEPKYTGIWHCVRDTYHRERVWGFYRG 55
+ +AG G V PL+ VK+R+Q T P+ + + VRD +G Y+G
Sbjct: 431 EILAGGCAGGSQVIFTNPLEIVKIRLQVAGEITTGPRVSAL-SVVRDL----GFFGIYKG 485
Query: 56 LSLPVCTVSLVSSVSFGT-YRHCLAHICRLRYGNPDAKPTKADITLSGCASGLVRVFLTS 114
+ + F Y C AH+ + + N D + + + L+G +G+ L +
Sbjct: 486 AK-----ACFLRDIPFSAIYFPCYAHV-KASFANEDGQVSPGSLLLAGAIAGMPAASLVT 539
Query: 115 PTEVAKVRLQTQTQAQKQQRRLSASGPLAVPPMCPVPPACPEPKYRGPLHCLATVAREEG 174
P +V K RLQ +A + Y G + C + REEG
Sbjct: 540 PADVIKTRLQVAARAG-------------------------QTTYSGVIDCFRKILREEG 574
Query: 175 LCGLYKGSSALVLRDGHSFATYFLSYAVLCEW 206
L+KG+ A V R F L+Y +L W
Sbjct: 575 PKALWKGAGARVFRSSPQFGVTLLTYELLQRW 606
>gi|237649019 solute carrier family 25, member 13 isoform 1 [Homo
sapiens]
Length = 676
Score = 115 bits (289), Expect = 4e-26
Identities = 94/311 (30%), Positives = 137/311 (44%), Gaps = 49/311 (15%)
Query: 3 FVAGAIGGVCGVAVGYPLDTVKVRIQT---------EPKYTGIWHCVRDTYHRERVWGFY 53
F G++ G G YP+D VK R+Q E Y + C + E +G Y
Sbjct: 333 FGLGSVAGAVGATAVYPIDLVKTRMQNQRSTGSFVGELMYKNSFDCFKKVLRYEGFFGLY 392
Query: 54 RGLSLPVCTVSLVSSVSFGTYRHCLAHICRLRYGNPDAK-PTKADITLSGCASGLVRVFL 112
RGL + V+ ++ + R ++ + D P A+I GCA G +V
Sbjct: 393 RGLLPQLLGVAPEKAIKL-----TVNDFVRDKFMHKDGSVPLAAEILAGGCAGGS-QVIF 446
Query: 113 TSPTEVAKVRLQTQTQAQKQQRRLSASGPLAVPPMCPVPPACPEPKYRGPLHCLATVARE 172
T+P E+ K+RLQ +G + GP +V R+
Sbjct: 447 TNPLEIVKIRLQV-------------AGEITT----------------GPRVSALSVVRD 477
Query: 173 EGLCGLYKGSSALVLRDGHSFATYFLSYA-VLCEWLSPAGHSRPDVPGVLVAGGCAGVLA 231
G G+YKG+ A LRD A YF YA V + + G P +L+AG AG+ A
Sbjct: 478 LGFFGIYKGAKACFLRDIPFSAIYFPCYAHVKASFANEDGQVSPG--SLLLAGAIAGMPA 535
Query: 232 WAVATPMDVIKSRLQADGQ-GQRRYRGLLHCMVTSVREEGPRVLFKGLVLNCCRAFPVNM 290
++ TP DVIK+RLQ + GQ Y G++ C +REEGP+ L+KG R+ P
Sbjct: 536 ASLVTPADVIKTRLQVAARAGQTTYSGVIDCFRKILREEGPKALWKGAGARVFRSSPQFG 595
Query: 291 VVFVAYEAVLR 301
V + YE + R
Sbjct: 596 VTLLTYELLQR 606
Score = 65.5 bits (158), Expect = 6e-11
Identities = 54/212 (25%), Positives = 85/212 (40%), Gaps = 43/212 (20%)
Query: 2 DFVAGAIGGVCGVAVGYPLDTVKVRIQ------TEPKYTGIWHCVRDTYHRERVWGFYRG 55
+ +AG G V PL+ VK+R+Q T P+ + + VRD +G Y+G
Sbjct: 432 EILAGGCAGGSQVIFTNPLEIVKIRLQVAGEITTGPRVSAL-SVVRDL----GFFGIYKG 486
Query: 56 LSLPVCTVSLVSSVSFGT-YRHCLAHICRLRYGNPDAKPTKADITLSGCASGLVRVFLTS 114
+ + F Y C AH+ + + N D + + + L+G +G+ L +
Sbjct: 487 AK-----ACFLRDIPFSAIYFPCYAHV-KASFANEDGQVSPGSLLLAGAIAGMPAASLVT 540
Query: 115 PTEVAKVRLQTQTQAQKQQRRLSASGPLAVPPMCPVPPACPEPKYRGPLHCLATVAREEG 174
P +V K RLQ +A + Y G + C + REEG
Sbjct: 541 PADVIKTRLQVAARAG-------------------------QTTYSGVIDCFRKILREEG 575
Query: 175 LCGLYKGSSALVLRDGHSFATYFLSYAVLCEW 206
L+KG+ A V R F L+Y +L W
Sbjct: 576 PKALWKGAGARVFRSSPQFGVTLLTYELLQRW 607
>gi|21389315 solute carrier family 25 (mitochondrial carrier;
citrate transporter), member 1 precursor [Homo sapiens]
Length = 311
Score = 111 bits (278), Expect = 7e-25
Identities = 92/307 (29%), Positives = 139/307 (45%), Gaps = 41/307 (13%)
Query: 4 VAGAIGGVCGVAVGYPLDTVKVRIQTE-----PKYTGIWHCVRDTYHRERVWGFYRGLSL 58
+AG + G + + +P + VK ++Q + P+Y GI CVR T V G YRGLS
Sbjct: 30 LAGGLAGGIEICITFPTEYVKTQLQLDERSHPPRYRGIGDCVRQTVRSHGVLGLYRGLSS 89
Query: 59 PVCTVSLVSSVSFGTYRHCLAHICRLRYGNPDAKPTKADITLSGCASGLVR-VFLTSPTE 117
+ ++V FG + H+ R G D+ T+ L G +G+ V + P E
Sbjct: 90 LLYGSIPKAAVRFGMFEFLSNHM-RDAQGRLDS--TRG--LLCGLGAGVAEAVVVVCPME 144
Query: 118 VAKVR-LQTQTQAQKQQRRLSASGPLAVPPMCPVPPACPEPKYRGPLHCLATVAREEGLC 176
KV+ + QT P PKYRG H + + RE+GL
Sbjct: 145 TIKVKFIHDQTS--------------------------PNPKYRGFFHGVREIVREQGLK 178
Query: 177 GLYKGSSALVLRDGHSFATYFLSYAVLCEWLSPAGHSRPDVPGVL-VAGGCAGVLAWAVA 235
G Y+G +A VL+ G + A F L W ++P P + V G AG +
Sbjct: 179 GTYQGLTATVLKQGSNQAIRFFVMTSLRNWYRGDNPNKPMNPLITGVFGAIAGAASVFGN 238
Query: 236 TPMDVIKSRLQADGQGQRRYRGLLHCMVTSVREEGPRVLFKGLVLNCCRAFPVNMVVFVA 295
TP+DVIK+R+Q G +YR C + +++EG + +KG V R +VFV
Sbjct: 239 TPLDVIKTRMQ--GLEAHKYRNTWDCGLQILKKEGLKAFYKGTVPRLGRVCLDVAIVFVI 296
Query: 296 YEAVLRL 302
Y+ V++L
Sbjct: 297 YDEVVKL 303
>gi|223468576 mitochondrial carrier protein-like [Homo sapiens]
Length = 157
Score = 107 bits (268), Expect = 1e-23
Identities = 53/129 (41%), Positives = 80/129 (62%), Gaps = 2/129 (1%)
Query: 2 DFVAGAIGGVCGVAVGYPLDTVKVRIQTEPKYTGIWHCVRDTYHRERVWGFYRGLSLPVC 61
DF AG IGG V VG+PLDTVK R+Q Y C+R Y RE ++GF++G+S P+
Sbjct: 8 DFAAGWIGGAASVIVGHPLDTVKTRLQAGVGYGNTLSCIRVVYRRESMFGFFKGMSFPLA 67
Query: 62 TVSLVSSVSFGTYRHCLAHICRLRYGNPDAKP--TKADITLSGCASGLVRVFLTSPTEVA 119
++++ +SV FG + + + + R G P+A P T +D+ L+ +G+V V L P ++
Sbjct: 68 SIAVYNSVVFGVFSNTQRFLSQHRCGEPEASPPRTLSDLLLASMVAGVVSVGLGGPVDLI 127
Query: 120 KVRLQTQTQ 128
K+RLQ QTQ
Sbjct: 128 KIRLQMQTQ 136
Score = 35.4 bits (80), Expect = 0.064
Identities = 27/98 (27%), Positives = 44/98 (44%), Gaps = 6/98 (6%)
Query: 159 YRGPLHCLATVAREEGLCGLYKGSSALVLRDGHSFATYFLSYAVLCEWLSPAGHSRPD-- 216
Y L C+ V R E + G +KG S + + F ++ +LS P+
Sbjct: 39 YGNTLSCIRVVYRRESMFGFFKGMSFPLASIAVYNSVVFGVFSNTQRFLSQHRCGEPEAS 98
Query: 217 ----VPGVLVAGGCAGVLAWAVATPMDVIKSRLQADGQ 250
+ +L+A AGV++ + P+D+IK RLQ Q
Sbjct: 99 PPRTLSDLLLASMVAGVVSVGLGGPVDLIKIRLQMQTQ 136
Score = 34.3 bits (77), Expect = 0.14
Identities = 26/79 (32%), Positives = 33/79 (41%), Gaps = 4/79 (5%)
Query: 223 AGGCAGVLAWAVATPMDVIKSRLQADGQGQRRYRGLLHCMVTSVREEGPRVLFKGLVLNC 282
AG G + V P+D +K+RLQA G G Y L C+ R E FKG+
Sbjct: 11 AGWIGGAASVIVGHPLDTVKTRLQA-GVG---YGNTLSCIRVVYRRESMFGFFKGMSFPL 66
Query: 283 CRAFPVNMVVFVAYEAVLR 301
N VVF + R
Sbjct: 67 ASIAVYNSVVFGVFSNTQR 85
>gi|13259541 uncoupling protein 2 [Homo sapiens]
Length = 309
Score = 105 bits (262), Expect = 5e-23
Identities = 81/298 (27%), Positives = 128/298 (42%), Gaps = 43/298 (14%)
Query: 16 VGYPLDTVKVRIQTE------------PKYTGIWHCVRDTYHRERVWGFYRGLSLPVCTV 63
+ +PLDT KVR+Q + +Y G+ + E Y GL
Sbjct: 30 ITFPLDTAKVRLQIQGESQGPVRATASAQYRGVMGTILTMVRTEGPRSLYNGL-----VA 84
Query: 64 SLVSSVSFGTYRHCLAHICRLRYGNPDAKPTKADITLSGCASGLVRVFLTSPTEVAKVRL 123
L +SF + R L + Y + L+G +G + V + PT+V KVR
Sbjct: 85 GLQRQMSFASVRIGLYDSVKQFYTKGSEHASIGSRLLAGSTTGALAVAVAQPTDVVKVRF 144
Query: 124 QTQTQAQKQQRRLSASGPLAVPPMCPVPPACPEPKYRGPLHCLATVAREEGLCGLYKGSS 183
Q Q +A +R Y+ ++ T+AREEG GL+KG+S
Sbjct: 145 QAQARAGGGRR------------------------YQSTVNAYKTIAREEGFRGLWKGTS 180
Query: 184 ALVLRDGHSFATYFLSYAVLCEWLSPAGHSRPDVPGVLVAGGCAGVLAWAVATPMDVIKS 243
V R+ ++Y ++ + L A D+P + AG +A+P+DV+K+
Sbjct: 181 PNVARNAIVNCAELVTYDLIKDALLKANLMTDDLPCHFTSAFGAGFCTTVIASPVDVVKT 240
Query: 244 RLQADGQGQRRYRGLLHCMVTSVREEGPRVLFKGLVLNCCRAFPVNMVVFVAYEAVLR 301
R GQ Y HC +T +++EGPR +KG + + R N+V+FV YE + R
Sbjct: 241 RYMNSALGQ--YSSAGHCALTMLQKEGPRAFYKGFMPSFLRLGSWNVVMFVTYEQLKR 296
Score = 83.6 bits (205), Expect = 2e-16
Identities = 68/212 (32%), Positives = 93/212 (43%), Gaps = 21/212 (9%)
Query: 90 DAKPTKADITLSGCASGLVRVFLTSPTEVAKVRLQTQTQAQKQQRRLSASGPLAVPPMCP 149
D PT L + + +T P + AKVRLQ Q ++Q GP+
Sbjct: 8 DVPPTATVKFLGAGTAACIADLITFPLDTAKVRLQIQGESQ---------GPVR------ 52
Query: 150 VPPACPEPKYRGPLHCLATVAREEGLCGLYKGSSALVLRDGHSFATYFLSYAVLCEWLSP 209
A +YRG + + T+ R EG LY G A + R SFA+ + +
Sbjct: 53 ---ATASAQYRGVMGTILTMVRTEGPRSLYNGLVAGLQRQ-MSFASVRIGLYDSVKQFYT 108
Query: 210 AGHSRPDVPGVLVAGGCAGVLAWAVATPMDVIKSRLQADGQ--GQRRYRGLLHCMVTSVR 267
G + L+AG G LA AVA P DV+K R QA + G RRY+ ++ T R
Sbjct: 109 KGSEHASIGSRLLAGSTTGALAVAVAQPTDVVKVRFQAQARAGGGRRYQSTVNAYKTIAR 168
Query: 268 EEGPRVLFKGLVLNCCRAFPVNMVVFVAYEAV 299
EEG R L+KG N R VN V Y+ +
Sbjct: 169 EEGFRGLWKGTSPNVARNAIVNCAELVTYDLI 200
Score = 43.9 bits (102), Expect = 2e-04
Identities = 51/217 (23%), Positives = 72/217 (33%), Gaps = 38/217 (17%)
Query: 4 VAGAIGGVCGVAVGYPLDTVKVRIQTEP------KYTGIWHCVRDTYHRERVWGFYRGLS 57
+AG+ G VAV P D VKVR Q + +Y + + E G ++G S
Sbjct: 121 LAGSTTGALAVAVAQPTDVVKVRFQAQARAGGGRRYQSTVNAYKTIAREEGFRGLWKGTS 180
Query: 58 LPVCTVSLVSSVSFGTYRHCLAHICRLRYGNPDAKPTKADITLSGCASGLVRVFLTSPTE 117
V ++V+ TY + + D T S +G + SP +
Sbjct: 181 PNVARNAIVNCAELVTYDLIKDALLKANLMTDD---LPCHFT-SAFGAGFCTTVIASPVD 236
Query: 118 VAKVRLQTQTQAQKQQRRLSASGPLAVPPMCPVPPACPEPKYRGPLHCLATVAREEGLCG 177
V K R Q Y HC T+ ++EG
Sbjct: 237 VVKTRYMNSALGQ----------------------------YSSAGHCALTMLQKEGPRA 268
Query: 178 LYKGSSALVLRDGHSFATYFLSYAVLCEWLSPAGHSR 214
YKG LR G F++Y L L A SR
Sbjct: 269 FYKGFMPSFLRLGSWNVVMFVTYEQLKRALMAACTSR 305
Score = 32.0 bits (71), Expect = 0.71
Identities = 19/74 (25%), Positives = 28/74 (37%), Gaps = 2/74 (2%)
Query: 3 FVAGAIGGVCGVAVGYPLDTVKVRIQTEP--KYTGIWHCVRDTYHRERVWGFYRGLSLPV 60
F + G C + P+D VK R +Y+ HC +E FY+G
Sbjct: 218 FTSAFGAGFCTTVIASPVDVVKTRYMNSALGQYSSAGHCALTMLQKEGPRAFYKGFMPSF 277
Query: 61 CTVSLVSSVSFGTY 74
+ + V F TY
Sbjct: 278 LRLGSWNVVMFVTY 291
>gi|11225256 uncoupling protein 1 [Homo sapiens]
Length = 307
Score = 102 bits (255), Expect = 3e-22
Identities = 85/307 (27%), Positives = 133/307 (43%), Gaps = 38/307 (12%)
Query: 3 FVAGAIGGVCGVAVGYPLDTVKVRIQTEP--------KYTGIWHCVRDTYHRERVWGFYR 54
F AG + V + +PLDT KVR+Q + +Y G+ + E Y
Sbjct: 18 FSAGIAACLADV-ITFPLDTAKVRLQVQGECPTSSVIRYKGVLGTITAVVKTEGRMKLYS 76
Query: 55 GLSLPVCTVSLVSSVSFGTYRHCLAHICRLRYGNPDAKPTKADITLSGCASGLVRVFLTS 114
GL + +S+ G Y + + P+ L+G +G V VF+
Sbjct: 77 GLPAGLQRQISSASLRIGLYDTVQEFLT----AGKETAPSLGSKILAGLTTGGVAVFIGQ 132
Query: 115 PTEVAKVRLQTQTQAQKQQRRLSASGPLAVPPMCPVPPACPEPKYRGPLHCLATVAREEG 174
PTEV KVRLQ Q+ + P+Y G + +A EG
Sbjct: 133 PTEVVKVRLQAQSHLHGIK-----------------------PRYTGTYNAYRIIATTEG 169
Query: 175 LCGLYKGSSALVLRDGHSFATYFLSYAVLCEWLSPAGHSRPDVPGVLVAGGCAGVLAWAV 234
L GL+KG++ ++R T ++Y ++ E DVP LV+ AG A A+
Sbjct: 170 LTGLWKGTTPNLMRSVIINCTELVTYDLMKEAFVKNNILADDVPCHLVSALIAGFCATAM 229
Query: 235 ATPMDVIKSRLQADGQGQRRYRGLLHCMVTSVREEGPRVLFKGLVLNCCRAFPVNMVVFV 294
++P+DV+K+R GQ Y+ + +C + EGP FKGLV + R N+++FV
Sbjct: 230 SSPVDVVKTRFINSPPGQ--YKSVPNCAMKVFTNEGPTAFFKGLVPSFLRLGSWNVIMFV 287
Query: 295 AYEAVLR 301
+E + R
Sbjct: 288 CFEQLKR 294
Score = 61.2 bits (147), Expect = 1e-09
Identities = 55/211 (26%), Positives = 83/211 (39%), Gaps = 25/211 (11%)
Query: 90 DAKPTKADITLSGCASGLVRVFLTSPTEVAKVRLQTQTQAQKQQRRLSASGPLAVPPMCP 149
D PT S + + +T P + AKVRLQ Q + CP
Sbjct: 8 DVHPTLGVQLFSAGIAACLADVITFPLDTAKVRLQVQGE-------------------CP 48
Query: 150 VPPACPEPKYRGPLHCLATVAREEGLCGLYKGSSALVLRDGHSFATYFLSYAVLCEWLSP 209
+Y+G L + V + EG LY G A + R S + Y + E+L+
Sbjct: 49 TSSVI---RYKGVLGTITAVVKTEGRMKLYSGLPAGLQRQISSASLRIGLYDTVQEFLTA 105
Query: 210 AGHSRPDVPGVLVAGGCAGVLAWAVATPMDVIKSRLQADGQ---GQRRYRGLLHCMVTSV 266
+ P + ++AG G +A + P +V+K RLQA + RY G +
Sbjct: 106 GKETAPSLGSKILAGLTTGGVAVFIGQPTEVVKVRLQAQSHLHGIKPRYTGTYNAYRIIA 165
Query: 267 REEGPRVLFKGLVLNCCRAFPVNMVVFVAYE 297
EG L+KG N R+ +N V Y+
Sbjct: 166 TTEGLTGLWKGTTPNLMRSVIINCTELVTYD 196
Score = 37.7 bits (86), Expect = 0.013
Identities = 24/73 (32%), Positives = 34/73 (46%), Gaps = 4/73 (5%)
Query: 210 AGHSRPDVPGVLVAGGCAGVLAWAVATPMDVIKSRLQADGQ----GQRRYRGLLHCMVTS 265
A P + L + G A LA + P+D K RLQ G+ RY+G+L +
Sbjct: 6 ASDVHPTLGVQLFSAGIAACLADVITFPLDTAKVRLQVQGECPTSSVIRYKGVLGTITAV 65
Query: 266 VREEGPRVLFKGL 278
V+ EG L+ GL
Sbjct: 66 VKTEGRMKLYSGL 78
>gi|4507807 uncoupling protein 3 isoform UCP3L [Homo sapiens]
Length = 312
Score = 100 bits (250), Expect = 1e-21
Identities = 85/298 (28%), Positives = 126/298 (42%), Gaps = 40/298 (13%)
Query: 16 VGYPLDTVKVRIQTEPK-----------YTGIWHCVRDTYHRERVWGFYRGLSLPVCTVS 64
V +PLDT KVR+Q + + Y G+ + E Y GL
Sbjct: 30 VTFPLDTAKVRLQIQGENQAVQTARLVQYRGVLGTILTMVRTEGPCSPYNGL-----VAG 84
Query: 65 LVSSVSFGTYRHCLAHICRLRYGNPDAKPTKADIT-LSGCASGLVRVFLTSPTEVAKVRL 123
L +SF + R L + Y A + L+GC +G + V PT+V KVR
Sbjct: 85 LQRQMSFASIRIGLYDSVKQVYTPKGADNSSLTTRILAGCTTGAMAVTCAQPTDVVKVRF 144
Query: 124 QTQTQAQKQQRRLSASGPLAVPPMCPVPPACPEPKYRGPLHCLATVAREEGLCGLYKGSS 183
Q + P+ + KY G + T+AREEG+ GL+KG+
Sbjct: 145 QASIH---------------------LGPSRSDRKYSGTMDAYRTIAREEGVRGLWKGTL 183
Query: 184 ALVLRDGHSFATYFLSYAVLCEWLSPAGHSRPDVPGVLVAGGCAGVLAWAVATPMDVIKS 243
++R+ ++Y +L E L + P V+ AG A VA+P+DV+K+
Sbjct: 184 PNIMRNAIVNCAEVVTYDILKEKLLDYHLLTDNFPCHFVSAFGAGFCATVVASPVDVVKT 243
Query: 244 RLQADGQGQRRYRGLLHCMVTSVREEGPRVLFKGLVLNCCRAFPVNMVVFVAYEAVLR 301
R GQ Y L CM+ V +EGP +KG + R N+V+FV YE + R
Sbjct: 244 RYMNSPPGQ--YFSPLDCMIKMVAQEGPTAFYKGFTPSFLRLGSWNVVMFVTYEQLKR 299
Score = 74.3 bits (181), Expect = 1e-13
Identities = 67/215 (31%), Positives = 91/215 (42%), Gaps = 28/215 (13%)
Query: 90 DAKPTKADITLSGCASGLVRVFLTSPTEVAKVRLQTQTQAQK-QQRRLSASGPLAVPPMC 148
D PT A L + +T P + AKVRLQ Q + Q Q RL
Sbjct: 8 DVPPTMAVKFLGAGTAACFADLVTFPLDTAKVRLQIQGENQAVQTARL------------ 55
Query: 149 PVPPACPEPKYRGPLHCLATVAREEGLCGLYKGSSALVLRDGHSFATYFLS-YAVLCEWL 207
+YRG L + T+ R EG C Y G A + R SFA+ + Y + +
Sbjct: 56 --------VQYRGVLGTILTMVRTEGPCSPYNGLVAGLQRQ-MSFASIRIGLYDSVKQVY 106
Query: 208 SPAGHSRPDVPGVLVAGGCAGVLAWAVATPMDVIKSRLQAD-----GQGQRRYRGLLHCM 262
+P G + ++AG G +A A P DV+K R QA + R+Y G +
Sbjct: 107 TPKGADNSSLTTRILAGCTTGAMAVTCAQPTDVVKVRFQASIHLGPSRSDRKYSGTMDAY 166
Query: 263 VTSVREEGPRVLFKGLVLNCCRAFPVNMVVFVAYE 297
T REEG R L+KG + N R VN V Y+
Sbjct: 167 RTIAREEGVRGLWKGTLPNIMRNAIVNCAEVVTYD 201
Score = 42.0 bits (97), Expect = 7e-04
Identities = 48/209 (22%), Positives = 70/209 (33%), Gaps = 41/209 (19%)
Query: 4 VAGAIGGVCGVAVGYPLDTVKVRIQ---------TEPKYTGIWHCVRDTYHRERVWGFYR 54
+AG G V P D VKVR Q ++ KY+G R E V G ++
Sbjct: 121 LAGCTTGAMAVTCAQPTDVVKVRFQASIHLGPSRSDRKYSGTMDAYRTIAREEGVRGLWK 180
Query: 55 GLSLPVCTVSLVSSVSFGTYRHCLAHICRLRYGNPDAKPTKADITLSGCASGLVRVFLTS 114
G + ++V+ TY L + D P +S +G + S
Sbjct: 181 GTLPNIMRNAIVNCAEVVTY-DILKEKLLDYHLLTDNFPCH---FVSAFGAGFCATVVAS 236
Query: 115 PTEVAKVRLQTQTQAQKQQRRLSASGPLAVPPMCPVPPACPEPKYRGPLHCLATVAREEG 174
P +V K R P +Y PL C+ + +EG
Sbjct: 237 PVDVVKTRYMNS----------------------------PPGQYFSPLDCMIKMVAQEG 268
Query: 175 LCGLYKGSSALVLRDGHSFATYFLSYAVL 203
YKG + LR G F++Y L
Sbjct: 269 PTAFYKGFTPSFLRLGSWNVVMFVTYEQL 297
Score = 32.3 bits (72), Expect = 0.54
Identities = 21/74 (28%), Positives = 30/74 (40%), Gaps = 2/74 (2%)
Query: 3 FVAGAIGGVCGVAVGYPLDTVKVRIQTEP--KYTGIWHCVRDTYHRERVWGFYRGLSLPV 60
FV+ G C V P+D VK R P +Y C+ +E FY+G +
Sbjct: 221 FVSAFGAGFCATVVASPVDVVKTRYMNSPPGQYFSPLDCMIKMVAQEGPTAFYKGFTPSF 280
Query: 61 CTVSLVSSVSFGTY 74
+ + V F TY
Sbjct: 281 LRLGSWNVVMFVTY 294
>gi|13899342 solute carrier [Homo sapiens]
Length = 315
Score = 92.4 bits (228), Expect = 4e-19
Identities = 78/292 (26%), Positives = 126/292 (43%), Gaps = 20/292 (6%)
Query: 4 VAGAIGGVCGVAVGYPLDTVKVRIQTE---PKYTGIWHCVRDTYHRERVWGFYRGLSLPV 60
+ G + G+ GV +P+D K R+Q + Y G+ C+ T E +G YRG ++ +
Sbjct: 13 INGGVAGLVGVTCVFPIDLAKTRLQNQHGKAMYKGMIDCLMKTARAEGFFGMYRGAAVNL 72
Query: 61 CTVSLVSSVSFGTYRHCLAHICRLRYGNPDAKPTKADITLSGCASGLVRVFLTSPTEVAK 120
V+ ++ RL + + K ++ L+GC +G+ +V +T P E+ K
Sbjct: 73 TLVTPEKAIKLAANDF----FRRLLMEDGMQRNLKMEM-LAGCGAGMCQVVVTCPMEMLK 127
Query: 121 VRLQTQTQAQKQQRRLSASGPLAVPPMCPVPPACPEPKYRGPLHCLAT--VAREEGLCGL 178
++LQ + + G + P +R P L + R +GL GL
Sbjct: 128 IQLQDAGRLAVHHQ-----GSASAPSTSRSYTTGSASTHRRPSATLIAWELLRTQGLAGL 182
Query: 179 YKGSSALVLRDGHSFATYFLSYAVLCEWLSPAGHSRPDVPGVLVAGGCAGVLAWAVATPM 238
Y+G A +LRD YF +A L + V+G AG +A TP+
Sbjct: 183 YRGLGATLLRDIPFSIIYFPLFANLNNLGFNELAGKASFAHSFVSGCVAGSIAAVAVTPL 242
Query: 239 DVIKSRLQA--DGQGQRRYRGLLHCMVTSVREEGPRVLFKGLVLNCCRAFPV 288
DV+K+R+Q G G+ Y G+ C +EGP KG CRA +
Sbjct: 243 DVLKTRIQTLKKGLGEDMYSGITDCARKLWIQEGPSAFMKGA---GCRALVI 291
Score = 47.8 bits (112), Expect = 1e-05
Identities = 25/91 (27%), Positives = 46/91 (50%), Gaps = 1/91 (1%)
Query: 212 HSRPDVPGVLVAGGCAGVLAWAVATPMDVIKSRLQADGQGQRRYRGLLHCMVTSVREEGP 271
H + L+ GG AG++ P+D+ K+RLQ + G+ Y+G++ C++ + R EG
Sbjct: 3 HQDLSITAKLINGGVAGLVGVTCVFPIDLAKTRLQ-NQHGKAMYKGMIDCLMKTARAEGF 61
Query: 272 RVLFKGLVLNCCRAFPVNMVVFVAYEAVLRL 302
+++G +N P + A + RL
Sbjct: 62 FGMYRGAAVNLTLVTPEKAIKLAANDFFRRL 92
Score = 44.3 bits (103), Expect = 1e-04
Identities = 49/217 (22%), Positives = 82/217 (37%), Gaps = 51/217 (23%)
Query: 100 LSGCASGLVRVFLTSPTEVAKVRLQTQTQAQKQQRRLSASGPLAVPPMCPVPPACPEPKY 159
++G +GLV V P ++AK RLQ Q + Y
Sbjct: 13 INGGVAGLVGVTCVFPIDLAKTRLQNQHG---------------------------KAMY 45
Query: 160 RGPLHCLATVAREEGLCGLYKGSSALVLRDGHSFATYFLSYAVLCEWLSPAGHSRPDVPG 219
+G + CL AR EG G+Y+G++ + A + L G R ++
Sbjct: 46 KGMIDCLMKTARAEGFFGMYRGAAVNLTLVTPEKAIKLAANDFFRRLLMEDGMQR-NLKM 104
Query: 220 VLVAGGCAGVLAWAVATPMDVIKSRLQADGQGQRRYRGLLHCMVTS-------------- 265
++AG AG+ V PM+++K +LQ G+ ++G TS
Sbjct: 105 EMLAGCGAGMCQVVVTCPMEMLKIQLQDAGRLAVHHQGSASAPSTSRSYTTGSASTHRRP 164
Query: 266 ---------VREEGPRVLFKGLVLNCCRAFPVNMVVF 293
+R +G L++GL R P +++ F
Sbjct: 165 SATLIAWELLRTQGLAGLYRGLGATLLRDIPFSIIYF 201
Score = 40.4 bits (93), Expect = 0.002
Identities = 23/78 (29%), Positives = 35/78 (44%), Gaps = 6/78 (7%)
Query: 3 FVAGAIGGVCGVAVGYPLDTVKVRIQT------EPKYTGIWHCVRDTYHRERVWGFYRGL 56
FV+G + G PLD +K RIQT E Y+GI C R + +E F +G
Sbjct: 225 FVSGCVAGSIAAVAVTPLDVLKTRIQTLKKGLGEDMYSGITDCARKLWIQEGPSAFMKGA 284
Query: 57 SLPVCTVSLVSSVSFGTY 74
++ + ++ G Y
Sbjct: 285 GCRALVIAPLFGIAQGVY 302
>gi|13259546 uncoupling protein 3 isoform UCP3S [Homo sapiens]
Length = 275
Score = 89.7 bits (221), Expect = 3e-18
Identities = 77/274 (28%), Positives = 114/274 (41%), Gaps = 40/274 (14%)
Query: 16 VGYPLDTVKVRIQTEPK-----------YTGIWHCVRDTYHRERVWGFYRGLSLPVCTVS 64
V +PLDT KVR+Q + + Y G+ + E Y GL
Sbjct: 30 VTFPLDTAKVRLQIQGENQAVQTARLVQYRGVLGTILTMVRTEGPCSPYNGL-----VAG 84
Query: 65 LVSSVSFGTYRHCLAHICRLRYGNPDAKPTKADIT-LSGCASGLVRVFLTSPTEVAKVRL 123
L +SF + R L + Y A + L+GC +G + V PT+V KVR
Sbjct: 85 LQRQMSFASIRIGLYDSVKQVYTPKGADNSSLTTRILAGCTTGAMAVTCAQPTDVVKVRF 144
Query: 124 QTQTQAQKQQRRLSASGPLAVPPMCPVPPACPEPKYRGPLHCLATVAREEGLCGLYKGSS 183
Q + P+ + KY G + T+AREEG+ GL+KG+
Sbjct: 145 QASIH---------------------LGPSRSDRKYSGTMDAYRTIAREEGVRGLWKGTL 183
Query: 184 ALVLRDGHSFATYFLSYAVLCEWLSPAGHSRPDVPGVLVAGGCAGVLAWAVATPMDVIKS 243
++R+ ++Y +L E L + P V+ AG A VA+P+DV+K+
Sbjct: 184 PNIMRNAIVNCAEVVTYDILKEKLLDYHLLTDNFPCHFVSAFGAGFCATVVASPVDVVKT 243
Query: 244 RLQADGQGQRRYRGLLHCMVTSVREEGPRVLFKG 277
R GQ Y L CM+ V +EGP +KG
Sbjct: 244 RYMNSPPGQ--YFSPLDCMIKMVAQEGPTAFYKG 275
Score = 74.3 bits (181), Expect = 1e-13
Identities = 65/214 (30%), Positives = 89/214 (41%), Gaps = 26/214 (12%)
Query: 90 DAKPTKADITLSGCASGLVRVFLTSPTEVAKVRLQTQTQAQKQQRRLSASGPLAVPPMCP 149
D PT A L + +T P + AKVRLQ Q + Q Q
Sbjct: 8 DVPPTMAVKFLGAGTAACFADLVTFPLDTAKVRLQIQGENQAVQTARLV----------- 56
Query: 150 VPPACPEPKYRGPLHCLATVAREEGLCGLYKGSSALVLRDGHSFATYFLS-YAVLCEWLS 208
+YRG L + T+ R EG C Y G A + R SFA+ + Y + + +
Sbjct: 57 --------QYRGVLGTILTMVRTEGPCSPYNGLVAGLQRQ-MSFASIRIGLYDSVKQVYT 107
Query: 209 PAGHSRPDVPGVLVAGGCAGVLAWAVATPMDVIKSRLQAD-----GQGQRRYRGLLHCMV 263
P G + ++AG G +A A P DV+K R QA + R+Y G +
Sbjct: 108 PKGADNSSLTTRILAGCTTGAMAVTCAQPTDVVKVRFQASIHLGPSRSDRKYSGTMDAYR 167
Query: 264 TSVREEGPRVLFKGLVLNCCRAFPVNMVVFVAYE 297
T REEG R L+KG + N R VN V Y+
Sbjct: 168 TIAREEGVRGLWKGTLPNIMRNAIVNCAEVVTYD 201
Score = 43.9 bits (102), Expect = 2e-04
Identities = 31/95 (32%), Positives = 43/95 (45%), Gaps = 11/95 (11%)
Query: 216 DVPGVL----VAGGCAGVLAWAVATPMDVIKSRLQADGQGQR-------RYRGLLHCMVT 264
DVP + + G A A V P+D K RLQ G+ Q +YRG+L ++T
Sbjct: 8 DVPPTMAVKFLGAGTAACFADLVTFPLDTAKVRLQIQGENQAVQTARLVQYRGVLGTILT 67
Query: 265 SVREEGPRVLFKGLVLNCCRAFPVNMVVFVAYEAV 299
VR EGP + GLV R + Y++V
Sbjct: 68 MVRTEGPCSPYNGLVAGLQRQMSFASIRIGLYDSV 102
Score = 36.6 bits (83), Expect = 0.029
Identities = 42/187 (22%), Positives = 61/187 (32%), Gaps = 41/187 (21%)
Query: 4 VAGAIGGVCGVAVGYPLDTVKVRIQ---------TEPKYTGIWHCVRDTYHRERVWGFYR 54
+AG G V P D VKVR Q ++ KY+G R E V G ++
Sbjct: 121 LAGCTTGAMAVTCAQPTDVVKVRFQASIHLGPSRSDRKYSGTMDAYRTIAREEGVRGLWK 180
Query: 55 GLSLPVCTVSLVSSVSFGTYRHCLAHICRLRYGNPDAKPTKADITLSGCASGLVRVFLTS 114
G + ++V+ TY L + D P +S +G + S
Sbjct: 181 GTLPNIMRNAIVNCAEVVTY-DILKEKLLDYHLLTDNFPCH---FVSAFGAGFCATVVAS 236
Query: 115 PTEVAKVRLQTQTQAQKQQRRLSASGPLAVPPMCPVPPACPEPKYRGPLHCLATVAREEG 174
P +V K R P +Y PL C+ + +EG
Sbjct: 237 PVDVVKTRYMNS----------------------------PPGQYFSPLDCMIKMVAQEG 268
Query: 175 LCGLYKG 181
YKG
Sbjct: 269 PTAFYKG 275
Score = 29.6 bits (65), Expect = 3.5
Identities = 17/55 (30%), Positives = 23/55 (41%), Gaps = 2/55 (3%)
Query: 3 FVAGAIGGVCGVAVGYPLDTVKVRIQTEP--KYTGIWHCVRDTYHRERVWGFYRG 55
FV+ G C V P+D VK R P +Y C+ +E FY+G
Sbjct: 221 FVSAFGAGFCATVVASPVDVVKTRYMNSPPGQYFSPLDCMIKMVAQEGPTAFYKG 275
>gi|21314739 solute carrier family 25, member 32 [Homo sapiens]
Length = 315
Score = 86.3 bits (212), Expect = 3e-17
Identities = 74/308 (24%), Positives = 127/308 (41%), Gaps = 39/308 (12%)
Query: 2 DFVAGAIGGVCGVAVGYPLDTVKVR------IQTEPKYTGIWHCVRDTYHRERVWGFYRG 55
+ +AG GGV +PLD VK+R ++ PKY GI HC+ + + + G Y+G
Sbjct: 25 NLIAGVSGGVLSNLALHPLDLVKIRFAVSDGLELRPKYNGILHCLTTIWKLDGLRGLYQG 84
Query: 56 LSLPVCTVSLVSSVSFGTYRHCLAHICRLRYGNPDAKPTKADITLSGCASGLVRVFLTSP 115
++ + L + F Y ++ R +A + +S +G + + +T+P
Sbjct: 85 VTPNIWGAGLSWGLYFFFYNAIKSYKTEGRAERLEA----TEYLVSAAEAGAMTLCITNP 140
Query: 116 TEVAKVRLQTQTQAQKQQRRLSASGPLAVPPMCPVPPACPEPKYRGPLHCLATVAREEGL 175
V K RL Q A P +Y+G L + + EG+
Sbjct: 141 LWVTKTRLMLQYDAVVNS---------------------PHRQYKGMFDTLVKIYKYEGV 179
Query: 176 CGLYKGSSALVLRDGHSFATYFLSYAVLC----EWLSPAGHSRPDVPGVLVAGGCAGVLA 231
GLYKG + H A F++Y +L + ++ ++ + + + A
Sbjct: 180 RGLYKGFVPGLFGTSHG-ALQFMAYELLKLKYNQHINRLPEAQLSTVEYISVAALSKIFA 238
Query: 232 WAVATPMDVIKSRLQADGQGQRRYRGLLHCMVTSVREEGPRVLFKGLVLNCCRAFPVNMV 291
A P V+++RLQ Y G++ + + R+EG +KG+ N R P +
Sbjct: 239 VAATYPYQVVRARLQDQ---HMFYSGVIDVITKTWRKEGVGGFYKGIAPNLIRVTPACCI 295
Query: 292 VFVAYEAV 299
FV YE V
Sbjct: 296 TFVVYENV 303
Score = 41.6 bits (96), Expect = 9e-04
Identities = 22/80 (27%), Positives = 41/80 (51%), Gaps = 1/80 (1%)
Query: 7 AIGGVCGVAVGYPLDTVKVRIQTEPK-YTGIWHCVRDTYHRERVWGFYRGLSLPVCTVSL 65
A+ + VA YP V+ R+Q + Y+G+ + T+ +E V GFY+G++ + V+
Sbjct: 232 ALSKIFAVAATYPYQVVRARLQDQHMFYSGVIDVITKTWRKEGVGGFYKGIAPNLIRVTP 291
Query: 66 VSSVSFGTYRHCLAHICRLR 85
++F Y + + LR
Sbjct: 292 ACCITFVVYENVSHFLLDLR 311
>gi|186928856 solute carrier family 25, member 19 [Homo sapiens]
Length = 320
Score = 84.3 bits (207), Expect = 1e-16
Identities = 70/220 (31%), Positives = 99/220 (45%), Gaps = 29/220 (13%)
Query: 90 DAKP-----TKADITLSGCASGLVRVFLTSPTEVAKVRLQTQTQAQKQQRRLSASGPLAV 144
D KP TK + ++G SGLV L SP +V K+R Q Q + RLS S P A
Sbjct: 5 DPKPDGRNNTKFQVAVAGSVSGLVTRALISPFDVIKIRFQLQHE------RLSRSDPSA- 57
Query: 145 PPMCPVPPACPEPKYRGPLHCLATVAREEGLCGLYKGS-SALVLRDGHSFATYFLSYAVL 203
KY G L + +EEG +KG A +L G+ A FLS+ +L
Sbjct: 58 -------------KYHGILQASRQILQEEGPTAFWKGHVPAQILSIGYG-AVQFLSFEML 103
Query: 204 CEWLSPAG-HSRPDVPGVLVAGGCAGVLAWAVATPMDVIKSRLQADGQGQRRYRGLLHCM 262
E + + + V GG A +A P+DV+++R A G+ + Y L H +
Sbjct: 104 TELVHRGSVYDAREFSVHFVCGGLAACMATLTVHPVDVLRTRFAAQGE-PKVYNTLRHAV 162
Query: 263 VTSVREEGPRVLFKGLVLNCCRAFPVNMVVFVAYEAVLRL 302
T R EGP+V +KGL FP + F Y ++ L
Sbjct: 163 GTMYRSEGPQVFYKGLAPTLIAIFPYAGLQFSCYSSLKHL 202
Score = 68.6 bits (166), Expect = 7e-12
Identities = 84/320 (26%), Positives = 127/320 (39%), Gaps = 61/320 (19%)
Query: 4 VAGAIGGVCGVAVGYPLDTVKVRIQTE----------PKYTGIWHCVRDTYHRERVWGFY 53
VAG++ G+ A+ P D +K+R Q + KY GI R E F+
Sbjct: 20 VAGSVSGLVTRALISPFDVIKIRFQLQHERLSRSDPSAKYHGILQASRQILQEEGPTAFW 79
Query: 54 RGLSLPVCTVSL-VSSVSFGTYRHC--LAHICRLRYGNPDAKPTKADITLSGCASGLVRV 110
+G +P +S+ +V F ++ L H R DA+ G A+ +
Sbjct: 80 KG-HVPAQILSIGYGAVQFLSFEMLTELVH----RGSVYDAREFSVHFVCGGLAA-CMAT 133
Query: 111 FLTSPTEVAKVRLQTQTQAQKQQRRLSASGPLAVPPMCPVPPACPEPK-YRGPLHCLATV 169
P +V + R Q EPK Y H + T+
Sbjct: 134 LTVHPVDVLRTRFAAQ----------------------------GEPKVYNTLRHAVGTM 165
Query: 170 AREEGLCGLYKGSS----ALVLRDGHSFATYFLSYAVLCEWLSPAGHSRPDVPGVLVAGG 225
R EG YKG + A+ G F+ Y S L +W PA + + L+ G
Sbjct: 166 YRSEGPQVFYKGLAPTLIAIFPYAGLQFSCY-SSLKHLYKWAIPAEGKKNENLQNLLCGS 224
Query: 226 CAGVLAWAVATPMDVIKSRLQADG-------QGQ-RRYRGLLHCMVTSVREEGPRVLFKG 277
AGV++ + P+D+ K RLQ G GQ RRY+GL+ C +++EG FKG
Sbjct: 225 GAGVISKTLTYPLDLFKKRLQVGGFEHARAAFGQVRRYKGLMDCAKQVLQKEGALGFFKG 284
Query: 278 LVLNCCRAFPVNMVVFVAYE 297
L + +A +F +YE
Sbjct: 285 LSPSLLKAALSTGFMFFSYE 304
Score = 61.2 bits (147), Expect = 1e-09
Identities = 52/205 (25%), Positives = 82/205 (40%), Gaps = 22/205 (10%)
Query: 3 FVAGAIGGVCGVAVGYPLDTVKVRI--QTEPK-YTGIWHCVRDTYHRERVWGFYRGLSLP 59
FV G + +P+D ++ R Q EPK Y + H V Y E FY+GL+
Sbjct: 122 FVCGGLAACMATLTVHPVDVLRTRFAAQGEPKVYNTLRHAVGTMYRSEGPQVFYKGLAPT 181
Query: 60 VCTVSLVSSVSFGTYRHCLAHICRLRYGNPDAKPTKADITLSGCASGLVRVFLTSPTEVA 119
+ + + + F Y L H+ + K L G +G++ LT P ++
Sbjct: 182 LIAIFPYAGLQFSCYSS-LKHLYKWAIPAEGKKNENLQNLLCGSGAGVISKTLTYPLDLF 240
Query: 120 KVRLQTQTQAQKQQRRLSASGPLAVPPMCPVPPACPEPKYRGPLHCLATVAREEGLCGLY 179
K RLQ + +A G + +Y+G + C V ++EG G +
Sbjct: 241 KKRLQVGGFEHAR----AAFGQVR--------------RYKGLMDCAKQVLQKEGALGFF 282
Query: 180 KGSSALVLRDGHSFATYFLSYAVLC 204
KG S +L+ S F SY C
Sbjct: 283 KGLSPSLLKAALSTGFMFFSYEFFC 307
Score = 38.9 bits (89), Expect = 0.006
Identities = 24/95 (25%), Positives = 40/95 (42%), Gaps = 18/95 (18%)
Query: 2 DFVAGAIGGVCGVAVGYPLDTVKVRIQT------------EPKYTGIWHCVRDTYHRERV 49
+ + G+ GV + YPLD K R+Q +Y G+ C + +E
Sbjct: 219 NLLCGSGAGVISKTLTYPLDLFKKRLQVGGFEHARAAFGQVRRYKGLMDCAKQVLQKEGA 278
Query: 50 WGFYRGLSLPVCTVSLVSSVSFGTYR------HCL 78
GF++GLS + +L + F +Y HC+
Sbjct: 279 LGFFKGLSPSLLKAALSTGFMFFSYEFFCNVFHCM 313
>gi|186928860 solute carrier family 25, member 19 [Homo sapiens]
Length = 320
Score = 84.3 bits (207), Expect = 1e-16
Identities = 70/220 (31%), Positives = 99/220 (45%), Gaps = 29/220 (13%)
Query: 90 DAKP-----TKADITLSGCASGLVRVFLTSPTEVAKVRLQTQTQAQKQQRRLSASGPLAV 144
D KP TK + ++G SGLV L SP +V K+R Q Q + RLS S P A
Sbjct: 5 DPKPDGRNNTKFQVAVAGSVSGLVTRALISPFDVIKIRFQLQHE------RLSRSDPSA- 57
Query: 145 PPMCPVPPACPEPKYRGPLHCLATVAREEGLCGLYKGS-SALVLRDGHSFATYFLSYAVL 203
KY G L + +EEG +KG A +L G+ A FLS+ +L
Sbjct: 58 -------------KYHGILQASRQILQEEGPTAFWKGHVPAQILSIGYG-AVQFLSFEML 103
Query: 204 CEWLSPAG-HSRPDVPGVLVAGGCAGVLAWAVATPMDVIKSRLQADGQGQRRYRGLLHCM 262
E + + + V GG A +A P+DV+++R A G+ + Y L H +
Sbjct: 104 TELVHRGSVYDAREFSVHFVCGGLAACMATLTVHPVDVLRTRFAAQGE-PKVYNTLRHAV 162
Query: 263 VTSVREEGPRVLFKGLVLNCCRAFPVNMVVFVAYEAVLRL 302
T R EGP+V +KGL FP + F Y ++ L
Sbjct: 163 GTMYRSEGPQVFYKGLAPTLIAIFPYAGLQFSCYSSLKHL 202
Score = 68.6 bits (166), Expect = 7e-12
Identities = 84/320 (26%), Positives = 127/320 (39%), Gaps = 61/320 (19%)
Query: 4 VAGAIGGVCGVAVGYPLDTVKVRIQTE----------PKYTGIWHCVRDTYHRERVWGFY 53
VAG++ G+ A+ P D +K+R Q + KY GI R E F+
Sbjct: 20 VAGSVSGLVTRALISPFDVIKIRFQLQHERLSRSDPSAKYHGILQASRQILQEEGPTAFW 79
Query: 54 RGLSLPVCTVSL-VSSVSFGTYRHC--LAHICRLRYGNPDAKPTKADITLSGCASGLVRV 110
+G +P +S+ +V F ++ L H R DA+ G A+ +
Sbjct: 80 KG-HVPAQILSIGYGAVQFLSFEMLTELVH----RGSVYDAREFSVHFVCGGLAA-CMAT 133
Query: 111 FLTSPTEVAKVRLQTQTQAQKQQRRLSASGPLAVPPMCPVPPACPEPK-YRGPLHCLATV 169
P +V + R Q EPK Y H + T+
Sbjct: 134 LTVHPVDVLRTRFAAQ----------------------------GEPKVYNTLRHAVGTM 165
Query: 170 AREEGLCGLYKGSS----ALVLRDGHSFATYFLSYAVLCEWLSPAGHSRPDVPGVLVAGG 225
R EG YKG + A+ G F+ Y S L +W PA + + L+ G
Sbjct: 166 YRSEGPQVFYKGLAPTLIAIFPYAGLQFSCY-SSLKHLYKWAIPAEGKKNENLQNLLCGS 224
Query: 226 CAGVLAWAVATPMDVIKSRLQADG-------QGQ-RRYRGLLHCMVTSVREEGPRVLFKG 277
AGV++ + P+D+ K RLQ G GQ RRY+GL+ C +++EG FKG
Sbjct: 225 GAGVISKTLTYPLDLFKKRLQVGGFEHARAAFGQVRRYKGLMDCAKQVLQKEGALGFFKG 284
Query: 278 LVLNCCRAFPVNMVVFVAYE 297
L + +A +F +YE
Sbjct: 285 LSPSLLKAALSTGFMFFSYE 304
Score = 61.2 bits (147), Expect = 1e-09
Identities = 52/205 (25%), Positives = 82/205 (40%), Gaps = 22/205 (10%)
Query: 3 FVAGAIGGVCGVAVGYPLDTVKVRI--QTEPK-YTGIWHCVRDTYHRERVWGFYRGLSLP 59
FV G + +P+D ++ R Q EPK Y + H V Y E FY+GL+
Sbjct: 122 FVCGGLAACMATLTVHPVDVLRTRFAAQGEPKVYNTLRHAVGTMYRSEGPQVFYKGLAPT 181
Query: 60 VCTVSLVSSVSFGTYRHCLAHICRLRYGNPDAKPTKADITLSGCASGLVRVFLTSPTEVA 119
+ + + + F Y L H+ + K L G +G++ LT P ++
Sbjct: 182 LIAIFPYAGLQFSCYSS-LKHLYKWAIPAEGKKNENLQNLLCGSGAGVISKTLTYPLDLF 240
Query: 120 KVRLQTQTQAQKQQRRLSASGPLAVPPMCPVPPACPEPKYRGPLHCLATVAREEGLCGLY 179
K RLQ + +A G + +Y+G + C V ++EG G +
Sbjct: 241 KKRLQVGGFEHAR----AAFGQVR--------------RYKGLMDCAKQVLQKEGALGFF 282
Query: 180 KGSSALVLRDGHSFATYFLSYAVLC 204
KG S +L+ S F SY C
Sbjct: 283 KGLSPSLLKAALSTGFMFFSYEFFC 307
Score = 38.9 bits (89), Expect = 0.006
Identities = 24/95 (25%), Positives = 40/95 (42%), Gaps = 18/95 (18%)
Query: 2 DFVAGAIGGVCGVAVGYPLDTVKVRIQT------------EPKYTGIWHCVRDTYHRERV 49
+ + G+ GV + YPLD K R+Q +Y G+ C + +E
Sbjct: 219 NLLCGSGAGVISKTLTYPLDLFKKRLQVGGFEHARAAFGQVRRYKGLMDCAKQVLQKEGA 278
Query: 50 WGFYRGLSLPVCTVSLVSSVSFGTYR------HCL 78
GF++GLS + +L + F +Y HC+
Sbjct: 279 LGFFKGLSPSLLKAALSTGFMFFSYEFFCNVFHCM 313
>gi|186928858 solute carrier family 25, member 19 [Homo sapiens]
Length = 320
Score = 84.3 bits (207), Expect = 1e-16
Identities = 70/220 (31%), Positives = 99/220 (45%), Gaps = 29/220 (13%)
Query: 90 DAKP-----TKADITLSGCASGLVRVFLTSPTEVAKVRLQTQTQAQKQQRRLSASGPLAV 144
D KP TK + ++G SGLV L SP +V K+R Q Q + RLS S P A
Sbjct: 5 DPKPDGRNNTKFQVAVAGSVSGLVTRALISPFDVIKIRFQLQHE------RLSRSDPSA- 57
Query: 145 PPMCPVPPACPEPKYRGPLHCLATVAREEGLCGLYKGS-SALVLRDGHSFATYFLSYAVL 203
KY G L + +EEG +KG A +L G+ A FLS+ +L
Sbjct: 58 -------------KYHGILQASRQILQEEGPTAFWKGHVPAQILSIGYG-AVQFLSFEML 103
Query: 204 CEWLSPAG-HSRPDVPGVLVAGGCAGVLAWAVATPMDVIKSRLQADGQGQRRYRGLLHCM 262
E + + + V GG A +A P+DV+++R A G+ + Y L H +
Sbjct: 104 TELVHRGSVYDAREFSVHFVCGGLAACMATLTVHPVDVLRTRFAAQGE-PKVYNTLRHAV 162
Query: 263 VTSVREEGPRVLFKGLVLNCCRAFPVNMVVFVAYEAVLRL 302
T R EGP+V +KGL FP + F Y ++ L
Sbjct: 163 GTMYRSEGPQVFYKGLAPTLIAIFPYAGLQFSCYSSLKHL 202
Score = 68.6 bits (166), Expect = 7e-12
Identities = 84/320 (26%), Positives = 127/320 (39%), Gaps = 61/320 (19%)
Query: 4 VAGAIGGVCGVAVGYPLDTVKVRIQTE----------PKYTGIWHCVRDTYHRERVWGFY 53
VAG++ G+ A+ P D +K+R Q + KY GI R E F+
Sbjct: 20 VAGSVSGLVTRALISPFDVIKIRFQLQHERLSRSDPSAKYHGILQASRQILQEEGPTAFW 79
Query: 54 RGLSLPVCTVSL-VSSVSFGTYRHC--LAHICRLRYGNPDAKPTKADITLSGCASGLVRV 110
+G +P +S+ +V F ++ L H R DA+ G A+ +
Sbjct: 80 KG-HVPAQILSIGYGAVQFLSFEMLTELVH----RGSVYDAREFSVHFVCGGLAA-CMAT 133
Query: 111 FLTSPTEVAKVRLQTQTQAQKQQRRLSASGPLAVPPMCPVPPACPEPK-YRGPLHCLATV 169
P +V + R Q EPK Y H + T+
Sbjct: 134 LTVHPVDVLRTRFAAQ----------------------------GEPKVYNTLRHAVGTM 165
Query: 170 AREEGLCGLYKGSS----ALVLRDGHSFATYFLSYAVLCEWLSPAGHSRPDVPGVLVAGG 225
R EG YKG + A+ G F+ Y S L +W PA + + L+ G
Sbjct: 166 YRSEGPQVFYKGLAPTLIAIFPYAGLQFSCY-SSLKHLYKWAIPAEGKKNENLQNLLCGS 224
Query: 226 CAGVLAWAVATPMDVIKSRLQADG-------QGQ-RRYRGLLHCMVTSVREEGPRVLFKG 277
AGV++ + P+D+ K RLQ G GQ RRY+GL+ C +++EG FKG
Sbjct: 225 GAGVISKTLTYPLDLFKKRLQVGGFEHARAAFGQVRRYKGLMDCAKQVLQKEGALGFFKG 284
Query: 278 LVLNCCRAFPVNMVVFVAYE 297
L + +A +F +YE
Sbjct: 285 LSPSLLKAALSTGFMFFSYE 304
Score = 61.2 bits (147), Expect = 1e-09
Identities = 52/205 (25%), Positives = 82/205 (40%), Gaps = 22/205 (10%)
Query: 3 FVAGAIGGVCGVAVGYPLDTVKVRI--QTEPK-YTGIWHCVRDTYHRERVWGFYRGLSLP 59
FV G + +P+D ++ R Q EPK Y + H V Y E FY+GL+
Sbjct: 122 FVCGGLAACMATLTVHPVDVLRTRFAAQGEPKVYNTLRHAVGTMYRSEGPQVFYKGLAPT 181
Query: 60 VCTVSLVSSVSFGTYRHCLAHICRLRYGNPDAKPTKADITLSGCASGLVRVFLTSPTEVA 119
+ + + + F Y L H+ + K L G +G++ LT P ++
Sbjct: 182 LIAIFPYAGLQFSCYSS-LKHLYKWAIPAEGKKNENLQNLLCGSGAGVISKTLTYPLDLF 240
Query: 120 KVRLQTQTQAQKQQRRLSASGPLAVPPMCPVPPACPEPKYRGPLHCLATVAREEGLCGLY 179
K RLQ + +A G + +Y+G + C V ++EG G +
Sbjct: 241 KKRLQVGGFEHAR----AAFGQVR--------------RYKGLMDCAKQVLQKEGALGFF 282
Query: 180 KGSSALVLRDGHSFATYFLSYAVLC 204
KG S +L+ S F SY C
Sbjct: 283 KGLSPSLLKAALSTGFMFFSYEFFC 307
Score = 38.9 bits (89), Expect = 0.006
Identities = 24/95 (25%), Positives = 40/95 (42%), Gaps = 18/95 (18%)
Query: 2 DFVAGAIGGVCGVAVGYPLDTVKVRIQT------------EPKYTGIWHCVRDTYHRERV 49
+ + G+ GV + YPLD K R+Q +Y G+ C + +E
Sbjct: 219 NLLCGSGAGVISKTLTYPLDLFKKRLQVGGFEHARAAFGQVRRYKGLMDCAKQVLQKEGA 278
Query: 50 WGFYRGLSLPVCTVSLVSSVSFGTYR------HCL 78
GF++GLS + +L + F +Y HC+
Sbjct: 279 LGFFKGLSPSLLKAALSTGFMFFSYEFFCNVFHCM 313
>gi|46409330 solute carrier family 25, member 34 [Homo sapiens]
Length = 304
Score = 81.6 bits (200), Expect = 8e-16
Identities = 87/320 (27%), Positives = 133/320 (41%), Gaps = 48/320 (15%)
Query: 1 MDFVAGAIGGVCGVAVGYPLDTVKVRIQ---------TEPK-YTGIWHCVRDTYHRERVW 50
+D V GA PL+ VK R+Q T P+ Y G V + +W
Sbjct: 8 VDLVLGASACCLACVFTNPLEVVKTRLQLQGELQARGTYPRPYHGFIASVAAVARADGLW 67
Query: 51 GFYRGLSLPVCTVSLVSSVSFGTYR-HCLAHICRLRYGNPDAKPTKADITLSGCASGLVR 109
G +GL+ + L++ V F Y C A + + G ++G +G +
Sbjct: 68 GLQKGLAAGLLYQGLMNGVRFYCYSLACQAGLTQQPGGT----------VVAGAVAGALG 117
Query: 110 VFLTSPTEVAKVRLQTQTQAQKQQRRLSASGPLAVPPMCPVPPACPEPKYRGPLHCLATV 169
F+ SP + K +LQ QT A +AV + ++ L L T+
Sbjct: 118 AFVGSPAYLIKTQLQAQTVAA-----------VAVGH---------QHNHQTVLGALETI 157
Query: 170 AREEGLCGLYKGSSALVLRDGHSFATYFLSYAVLCEWLSPAGHSRPDVPGVLVAGGCAGV 229
R++GL GL++G V R A ++A W+ D V +AGG
Sbjct: 158 WRQQGLLGLWQGVGGAVPRVMVGSAAQLATFASAKAWVQKQQWLPEDSWLVALAGGMISS 217
Query: 230 LAWAVA-TPMDVIKSRL-----QADGQGQRRYRGLLHCMVTSVREEGPRVLFKGLVLNCC 283
+A V TP DV+ +RL G+GQ Y GL CMV R+EGP L+KGL
Sbjct: 218 IAVVVVMTPFDVVSTRLYNQPVDTAGRGQL-YGGLTDCMVKIWRQEGPLALYKGLGPAYL 276
Query: 284 RAFPVNMVVFVAYEAVLRLA 303
R P ++ + ++ + +LA
Sbjct: 277 RLGPHTILSMLFWDELRKLA 296
Score = 64.7 bits (156), Expect = 1e-10
Identities = 60/192 (31%), Positives = 88/192 (45%), Gaps = 32/192 (16%)
Query: 93 PTKADITLSGCASGLVRVFLTSPTEVAKVRLQTQTQAQKQQRRLSASGPLAVPPMCPVPP 152
P D+ L A L VF T+P EV K RLQ Q + Q +
Sbjct: 5 PPAVDLVLGASACCLACVF-TNPLEVVKTRLQLQGELQARG------------------- 44
Query: 153 ACPEPKYRGPLHCLATVAREEGLCGLYKGSSALVLRDGHSFATYFLSYAVLCEWLSPAGH 212
P P Y G + +A VAR +GL GL KG +A +L G F Y++ C+ AG
Sbjct: 45 TYPRP-YHGFIASVAAVARADGLWGLQKGLAAGLLYQGLMNGVRFYCYSLACQ----AGL 99
Query: 213 SRPDVPGVLVAGGCAGVLAWAVATPMDVIKSRLQADGQG------QRRYRGLLHCMVTSV 266
++ G +VAG AG L V +P +IK++LQA Q ++ +L + T
Sbjct: 100 TQ-QPGGTVVAGAVAGALGAFVGSPAYLIKTQLQAQTVAAVAVGHQHNHQTVLGALETIW 158
Query: 267 REEGPRVLFKGL 278
R++G L++G+
Sbjct: 159 RQQGLLGLWQGV 170
>gi|20149598 solute carrier family 25 (mitochondrial carrier;
dicarboxylate transporter), member 10 [Homo sapiens]
Length = 287
Score = 79.7 bits (195), Expect = 3e-15
Identities = 79/291 (27%), Positives = 119/291 (40%), Gaps = 38/291 (13%)
Query: 12 CGVAV-GYPLDTVKVRIQTEP----KYTGIWHCVRDTYHRERVWGFYRGLSLPVCTVSLV 66
CG A +PLD +KV +QT+ + TG+ V T + + Y GLS +C
Sbjct: 18 CGAACCTHPLDLLKVHLQTQQEVKLRMTGMALRVVRT---DGILALYSGLSASLCRQMTY 74
Query: 67 SSVSFGTYRHCLAHICRLRYGNPDAKPTKADITLSGCASGLVRVFLTSPTEVAKVRLQTQ 126
S F Y + + G+ P + L G SGL F+ +P ++ VR+Q
Sbjct: 75 SLTRFAIYETVRDRVAK---GSQGPLPFHEKVLL-GSVSGLAGGFVGTPADLVNVRMQND 130
Query: 127 TQAQKQQRRLSASGPLAVPPMCPVPPACPEPKYRGPLHCLATVAREEGLCGLYKGSSALV 186
+ + QRR Y L L VAREEGL L+ G++
Sbjct: 131 VKLPQGQRR----------------------NYAHALDGLYRVAREEGLRRLFSGATMAS 168
Query: 187 LRDGHSFATYFLSYAVLCEWLSPAGHSRPDVPGVLVAGGCAGVLAWAVATPMDVIKSRLQ 246
R Y + + G+ ++ VA AG A + P+DV+K+RL
Sbjct: 169 SRGALVTVGQLSCYDQAKQLVLSTGYLSDNIFTHFVASFIAGGCATFLCQPLDVLKTRLM 228
Query: 247 ADGQGQRRYRGLLHCMVTSVREEGPRVLFKGLVLNCCRAFPVNMVVFVAYE 297
+ Y+G+ HC V + + GP +KGLV R P ++ FV E
Sbjct: 229 ---NSKGEYQGVFHCAVETAK-LGPLAFYKGLVPAGIRLIPHTVLTFVFLE 275
Score = 50.4 bits (119), Expect = 2e-06
Identities = 40/138 (28%), Positives = 59/138 (42%), Gaps = 4/138 (2%)
Query: 169 VAREEGLCGLYKGSSALVLRDGHSFATYFLSYAVLCEWLSPAGHSRPDVPGVLVAGGCAG 228
V R +G+ LY G SA + R T F Y + + ++ ++ G +G
Sbjct: 51 VVRTDGILALYSGLSASLCRQMTYSLTRFAIYETVRDRVAKGSQGPLPFHEKVLLGSVSG 110
Query: 229 VLAWAVATPMDVIKSRLQAD---GQGQRR-YRGLLHCMVTSVREEGPRVLFKGLVLNCCR 284
+ V TP D++ R+Q D QGQRR Y L + REEG R LF G + R
Sbjct: 111 LAGGFVGTPADLVNVRMQNDVKLPQGQRRNYAHALDGLYRVAREEGLRRLFSGATMASSR 170
Query: 285 AFPVNMVVFVAYEAVLRL 302
V + Y+ +L
Sbjct: 171 GALVTVGQLSCYDQAKQL 188
Score = 38.9 bits (89), Expect = 0.006
Identities = 26/83 (31%), Positives = 40/83 (48%), Gaps = 4/83 (4%)
Query: 224 GGCAGVLAWAVATPMDVIKSRLQADGQGQRRYRGLLHCMVTSVREEGPRVLFKGLVLNCC 283
GG A A P+D++K LQ + + R G+ + VR +G L+ GL + C
Sbjct: 13 GGLASCGAACCTHPLDLLKVHLQTQQEVKLRMTGMA---LRVVRTDGILALYSGLSASLC 69
Query: 284 RAFPVNMVVFVAYEAVL-RLARG 305
R ++ F YE V R+A+G
Sbjct: 70 RQMTYSLTRFAIYETVRDRVAKG 92
Score = 37.0 bits (84), Expect = 0.022
Identities = 20/55 (36%), Positives = 31/55 (56%), Gaps = 2/55 (3%)
Query: 3 FVAGAIGGVCGVAVGYPLDTVKVRI-QTEPKYTGIWHCVRDTYHRERVWGFYRGL 56
FVA I G C + PLD +K R+ ++ +Y G++HC +T + FY+GL
Sbjct: 203 FVASFIAGGCATFLCQPLDVLKTRLMNSKGEYQGVFHCAVETAKLGPL-AFYKGL 256
Score = 30.4 bits (67), Expect = 2.1
Identities = 33/127 (25%), Positives = 48/127 (37%), Gaps = 14/127 (11%)
Query: 6 GAIGGVCGVAVGYPLDTVKVRIQTEPKY-----TGIWHCVRDTYHRERVWGFYR---GLS 57
G++ G+ G VG P D V VR+Q + K H + Y R G R G +
Sbjct: 106 GSVSGLAGGFVGTPADLVNVRMQNDVKLPQGQRRNYAHALDGLYRVAREEGLRRLFSGAT 165
Query: 58 LPVCTVSLVSSVSFGTYRHCLAHICRLRYGNPDA-KPTKADITLSGCASGLVRVFLTSPT 116
+ +LV+ Y + Y + + A GCA+ FL P
Sbjct: 166 MASSRGALVTVGQLSCYDQAKQLVLSTGYLSDNIFTHFVASFIAGGCAT-----FLCQPL 220
Query: 117 EVAKVRL 123
+V K RL
Sbjct: 221 DVLKTRL 227
>gi|13449279 solute carrier family 25 (mitochondrial
oxodicarboxylate carrier), member 21 [Homo sapiens]
Length = 299
Score = 77.4 bits (189), Expect = 1e-14
Identities = 81/306 (26%), Positives = 122/306 (39%), Gaps = 46/306 (15%)
Query: 4 VAGAIGGVCGVAVGYPLDTVKVRIQ-----TEP-KYTGIWHCVRDTYHRERVWGFYRGLS 57
VAG G+ + + +PLD VK R Q T+P Y + R + E ++GFY+G+
Sbjct: 18 VAGGSAGLVEICLMHPLDVVKTRFQIQRCATDPNSYKSLVDSFRMIFQMEGLFGFYKGIL 77
Query: 58 LPVCTVSLVSSVSFGT---YRHCLAHICRLRYGNPDAKPTKADITLSGCASGLVRVFLTS 114
P+ + +V F T Y+ L ++ + ++G SGL + +
Sbjct: 78 PPILAETPKRAVKFFTFEQYKKLLGYV---------SLSPALTFAIAGLGSGLTEAIVVN 128
Query: 115 PTEVAKVRLQTQTQAQKQQRRLSASGPLAVPPMCPVPPACPEPKYRGPLHCLATVAREE- 173
P EV KV LQ R A P V + + +E
Sbjct: 129 PFEVVKVGLQA-------NRNTFAEQPSTVG------------------YARQIIKKEGW 163
Query: 174 GLCGLYKGSSALVLRDGHSFATYFLSYAVLCEWLSPAGHSRPDVPGVLVAGGCAGVLAWA 233
GL GL KG +A + R G YF Y + + + G +G +A
Sbjct: 164 GLQGLNKGLTATLGRHGVFNMVYFGFYYNVKNMIPVNKDPILEFWRKFGIGLLSGTIASV 223
Query: 234 VATPMDVIKSRLQADG--QGQRRYRGLLHCMVTSVREEGPRVLFKGLVLNCCRAFPVNMV 291
+ P DV KSR+Q G+ +YR M T +EEG L+KGL+ R P V
Sbjct: 224 INIPFDVAKSRIQGPQPVPGEIKYRTCFKTMATVYQEEGILALYKGLLPKIMRLGPGGAV 283
Query: 292 VFVAYE 297
+ + YE
Sbjct: 284 MLLVYE 289
Score = 47.8 bits (112), Expect = 1e-05
Identities = 59/221 (26%), Positives = 80/221 (36%), Gaps = 56/221 (25%)
Query: 4 VAGAIGGVCGVAVGYPLDTVKVRIQT-------EPKYTGIWHCVRDTYHRERVWGFY--- 53
+AG G+ V P + VKV +Q +P G R +E WG
Sbjct: 114 IAGLGSGLTEAIVVNPFEVVKVGLQANRNTFAEQPSTVGY---ARQIIKKEG-WGLQGLN 169
Query: 54 RGLSLPVCTVSLVSSVSFGTYRHCLAHICRLRYGNPDAKPTKADITLS-------GCASG 106
+GL+ + + + V FG Y Y + P D L G SG
Sbjct: 170 KGLTATLGRHGVFNMVYFGFY-----------YNVKNMIPVNKDPILEFWRKFGIGLLSG 218
Query: 107 LVRVFLTSPTEVAKVRLQTQTQAQKQQRRLSASGPLAVPPMCPVPPACPEPKYRGPLHCL 166
+ + P +VAK R+Q GP VP E KYR +
Sbjct: 219 TIASVINIPFDVAKSRIQ---------------GPQPVPG---------EIKYRTCFKTM 254
Query: 167 ATVAREEGLCGLYKGSSALVLRDGHSFATYFLSYAVLCEWL 207
ATV +EEG+ LYKG ++R G A L Y WL
Sbjct: 255 ATVYQEEGILALYKGLLPKIMRLGPGGAVMLLVYEYTYSWL 295
Score = 35.4 bits (80), Expect = 0.064
Identities = 23/84 (27%), Positives = 38/84 (45%), Gaps = 2/84 (2%)
Query: 221 LVAGGCAGVLAWAVATPMDVIKSRLQAD--GQGQRRYRGLLHCMVTSVREEGPRVLFKGL 278
+VAGG AG++ + P+DV+K+R Q Y+ L+ + EG +KG+
Sbjct: 17 IVAGGSAGLVEICLMHPLDVVKTRFQIQRCATDPNSYKSLVDSFRMIFQMEGLFGFYKGI 76
Query: 279 VLNCCRAFPVNMVVFVAYEAVLRL 302
+ P V F +E +L
Sbjct: 77 LPPILAETPKRAVKFFTFEQYKKL 100
Score = 28.9 bits (63), Expect = 6.0
Identities = 17/60 (28%), Positives = 23/60 (38%), Gaps = 6/60 (10%)
Query: 3 FVAGAIGGVCGVAVGYPLDTVKVRIQ------TEPKYTGIWHCVRDTYHRERVWGFYRGL 56
F G + G + P D K RIQ E KY + + Y E + Y+GL
Sbjct: 211 FGIGLLSGTIASVINIPFDVAKSRIQGPQPVPGEIKYRTCFKTMATVYQEEGILALYKGL 270
>gi|27544933 solute carrier family 25, member 16 [Homo sapiens]
Length = 332
Score = 77.4 bits (189), Expect = 1e-14
Identities = 84/322 (26%), Positives = 122/322 (37%), Gaps = 65/322 (20%)
Query: 3 FVAGAIGGVCGVAVGYPLDTVKVRIQTEP---KYTGIWHCVRDTYHRERVWGFYRGLSLP 59
F+AG I G C PLD VKV +Q K+ G++ +R +E G Y+G
Sbjct: 40 FLAGGIAGCCAKTTVAPLDRVKVLLQAHNHHYKHLGVFSALRAVPQKEGFLGLYKGNGAM 99
Query: 60 VCTVSLVSSVSFGTYRHCLAHICRLRYGNPDAKPTKADIT------LSGCASGLVRVFLT 113
+ + ++ F + H I TK I+ ++G +G+ V T
Sbjct: 100 MIRIFPYGAIQFMAFEHYKTLI-----------TTKLGISGHVHRLMAGSMAGMTAVICT 148
Query: 114 SPTEVAKVRLQTQTQAQKQQRRLSASGPLAVPPMCPVPPACPEPKYRGPLHCLATV-ARE 172
P ++ +VRL Q + E Y G +H T+ A+E
Sbjct: 149 YPLDMVRVRLAFQVKG--------------------------EHSYTGIIHAFKTIYAKE 182
Query: 173 EGLCGLYKGSSALVL----RDGHSFATY-FLSYAVLCEWLSPAGHSRPDVPGVLV----- 222
G G Y+G +L G SF T+ L L + G D P VLV
Sbjct: 183 GGFFGFYRGLMPTILGMAPYAGVSFFTFGTLKSVGLSHAPTLLGRPSSDNPNVLVLKTHV 242
Query: 223 ---AGGCAGVLAWAVATPMDVIKSRLQADGQGQRRYRGLLHCMVTSVREEG----PRVLF 275
GG AG +A ++ P DV + R+Q G + L T G + L+
Sbjct: 243 NLLCGGVAGAIAQTISYPFDVTRRRMQL-GTVLPEFEKCLTMRDTMKYVYGHHGIRKGLY 301
Query: 276 KGLVLNCCRAFPVNMVVFVAYE 297
+GL LN R P V F YE
Sbjct: 302 RGLSLNYIRCIPSQAVAFTTYE 323
Score = 32.3 bits (72), Expect = 0.54
Identities = 23/81 (28%), Positives = 33/81 (40%), Gaps = 7/81 (8%)
Query: 1 MDFVAGAIGGVCGVAVGYPLDTVKVRIQTEPKYTGIWHC--VRDTY-----HRERVWGFY 53
++ + G + G + YP D + R+Q C +RDT H G Y
Sbjct: 242 VNLLCGGVAGAIAQTISYPFDVTRRRMQLGTVLPEFEKCLTMRDTMKYVYGHHGIRKGLY 301
Query: 54 RGLSLPVCTVSLVSSVSFGTY 74
RGLSL +V+F TY
Sbjct: 302 RGLSLNYIRCIPSQAVAFTTY 322
>gi|82775373 solute carrier family 25, member 37 [Homo sapiens]
Length = 338
Score = 76.3 bits (186), Expect = 3e-14
Identities = 70/305 (22%), Positives = 125/305 (40%), Gaps = 46/305 (15%)
Query: 5 AGAIGGVCGVAVGYPLDTVKVRIQT---EPK--YTGIWHCVRDTYHRERVWGFYRGLSLP 59
AGA+ G+ +V YP+D+VK R+Q+ +PK YT I+ ++ E W RG+++
Sbjct: 51 AGAMAGILEHSVMYPVDSVKTRMQSLSPDPKAQYTSIYGALKKIMRTEGFWRPLRGVNVM 110
Query: 60 VCTVSLVSSVSFGTYRHCLAHICRLRYGNPDAKPTKADITLSGCASGLVRVFLTSPTEVA 119
+ ++ F Y + + + + ++ ++G + L+ + +P EV
Sbjct: 111 IMGAGPAHAMYFACYENMKRTLNDVFHHQGNSHLANG---IAGSMATLLHDAVMNPAEVV 167
Query: 120 KVRLQTQTQAQKQQRRLSASGPLAVPPMCPVPPACPEPKYRGPLHCLATVAREEGLCGLY 179
K RLQ ++R + C+ TV R EGL Y
Sbjct: 168 KQRLQMYNS-----------------------------QHRSAISCIRTVWRTEGLGAFY 198
Query: 180 KGSSALVLRDGHSFATYFLSYAVLCEWLSPAGHSRPDVPGVLVAGGCAGVLAWAVATPMD 239
+ + + + + +F++Y L E ++P H + +++GG AG LA A TP+D
Sbjct: 199 RSYTTQLTMNIPFQSIHFITYEFLQEQVNP--HRTYNPQSHIISGGLAGALAAAATTPLD 256
Query: 240 VIKSRLQAD-------GQGQRRYRGLLHCMVTSVREEGPRVLFKGLVLNCCRAFPVNMVV 292
V K+ L R G+ + T + G FKG+ P +
Sbjct: 257 VCKTLLNTQENVALSLANISGRLSGMANAFRTVYQLNGLAGYFKGIQARVIYQMPSTAIS 316
Query: 293 FVAYE 297
+ YE
Sbjct: 317 WSVYE 321
Score = 46.6 bits (109), Expect = 3e-05
Identities = 43/185 (23%), Positives = 70/185 (37%), Gaps = 26/185 (14%)
Query: 4 VAGAIGGVCGVAVGYPLDTVKVRIQT-EPKYTGIWHCVRDTYHRERVWGFYRGLSLPVCT 62
+AG++ + AV P + VK R+Q ++ C+R + E + FYR + +
Sbjct: 148 IAGSMATLLHDAVMNPAEVVKQRLQMYNSQHRSAISCIRTVWRTEGLGAFYRSYTTQLTM 207
Query: 63 VSLVSSVSFGTYRHCLAHICRLRYGNPDAKPTKADITLSGCASGLVRVFLTSPTEVAKVR 122
S+ F TY + R NP + +SG +G + T+P +V K
Sbjct: 208 NIPFQSIHFITYEFLQEQVNPHRTYNPQSH------IISGGLAGALAAAATTPLDVCKTL 261
Query: 123 LQTQTQAQKQQRRLSASGPLAVPPMCPVPPACPEPKYRGPLHCLATVAREEGLCGLYKGS 182
L TQ +S + G + TV + GL G +KG
Sbjct: 262 LNTQENVALSLANISG-------------------RLSGMANAFRTVYQLNGLAGYFKGI 302
Query: 183 SALVL 187
A V+
Sbjct: 303 QARVI 307
Score = 35.4 bits (80), Expect = 0.064
Identities = 22/82 (26%), Positives = 41/82 (50%), Gaps = 1/82 (1%)
Query: 221 LVAGGCAGVLAWAVATPMDVIKSRLQA-DGQGQRRYRGLLHCMVTSVREEGPRVLFKGLV 279
+ AG AG+L +V P+D +K+R+Q+ + +Y + + +R EG +G+
Sbjct: 49 MTAGAMAGILEHSVMYPVDSVKTRMQSLSPDPKAQYTSIYGALKKIMRTEGFWRPLRGVN 108
Query: 280 LNCCRAFPVNMVVFVAYEAVLR 301
+ A P + + F YE + R
Sbjct: 109 VMIMGAGPAHAMYFACYENMKR 130
>gi|157388989 solute carrier family 25, member 36 isoform a [Homo
sapiens]
Length = 311
Score = 74.7 bits (182), Expect = 1e-13
Identities = 71/334 (21%), Positives = 127/334 (38%), Gaps = 67/334 (20%)
Query: 5 AGAIGGVCGVAVGYPLDTVKVRIQTEPKYT---------------------GIWHCVRDT 43
AG GG G + PL+ VK R+Q+ G HC++
Sbjct: 12 AGGCGGTVGAILTCPLEVVKTRLQSSSVTLYISEVQLNTMAGASVNRVVSPGPLHCLKVI 71
Query: 44 YHRERVWGFYRGLSLPVCTVSLVSSVSFGTYRHCLAHICRLRYGNPDAKPTKADI-TLSG 102
+E +RGL + V+ ++ F Y +C + N P + +S
Sbjct: 72 LEKEGPRSLFRGLGPNLVGVAPSRAIYFAAYSNCKEKL------NDVFDPDSTQVHMISA 125
Query: 103 CASGLVRVFLTSPTEVAKVRLQTQTQAQKQQRRLSASGPLAVPPMCPVPPACPEPKYRGP 162
+G + T+P + K RLQ + + ++R G
Sbjct: 126 AMAGFTAITATNPIWLIKTRLQLDARNRGERRM-------------------------GA 160
Query: 163 LHCLATVAREEGLCGLYKGSSALVLRDGHSFATYFLSYAV---LCEWLSPAGHSRP---- 215
C+ V + +GL G Y+G SA + + + ++ L E+ + +
Sbjct: 161 FECVRKVYQTDGLKGFYRGMSASYAGISETVIHFVIYESIKQKLLEYKTASTMENDEESV 220
Query: 216 ----DVPGVLVAGGCAGVLAWAVATPMDVIKSRLQADGQGQRRYRGLLHCMVTSVREEGP 271
D G+++A + A +A P +V+++RL+ +G +YR + V+EEG
Sbjct: 221 KEASDFVGMMLAAATSKTCATTIAYPHEVVRTRLREEGT---KYRSFFQTLSLLVQEEGY 277
Query: 272 RVLFKGLVLNCCRAFPVNMVVFVAYEAVLRLARG 305
L++GL + R P ++ YE V+ L G
Sbjct: 278 GSLYRGLTTHLVRQIPNTAIMMATYELVVYLLNG 311
Score = 50.8 bits (120), Expect = 1e-06
Identities = 31/93 (33%), Positives = 43/93 (46%), Gaps = 17/93 (18%)
Query: 221 LVAGGCAGVLAWAVATPMDVIKSRLQAD---------------GQGQRRY--RGLLHCMV 263
L AGGC G + + P++V+K+RLQ+ G R G LHC+
Sbjct: 10 LFAGGCGGTVGAILTCPLEVVKTRLQSSSVTLYISEVQLNTMAGASVNRVVSPGPLHCLK 69
Query: 264 TSVREEGPRVLFKGLVLNCCRAFPVNMVVFVAY 296
+ +EGPR LF+GL N P + F AY
Sbjct: 70 VILEKEGPRSLFRGLGPNLVGVAPSRAIYFAAY 102
>gi|58197562 solute carrier family 25, member 30 [Homo sapiens]
Length = 291
Score = 74.3 bits (181), Expect = 1e-13
Identities = 69/315 (21%), Positives = 127/315 (40%), Gaps = 49/315 (15%)
Query: 3 FVAGAIGGVCGVAVGYPLDTVKVRIQT----------EPKYTGIWHCVRDTYHRERVWGF 52
FV G + + +P+D K R+Q E +Y G+ H + E +
Sbjct: 9 FVYGGLASITAECGTFPIDLTKTRLQIQGQTNDAKFKEIRYRGMLHALVRIGREEGLKAL 68
Query: 53 YRGLSLPVCTVSLVSSVSFGTYRHCLAHICRLRYGNPDAKPTKADITLSGCASGLVRVFL 112
Y G++ + + ++ GTY+ + RL P+ + ++ + G SG++ +
Sbjct: 69 YSGIAPAMLRQASYGTIKIGTYQS----LKRLFIERPEDETLPINV-ICGILSGVISSTI 123
Query: 113 TSPTEVAKVRLQTQTQAQKQQRRLSASGPLAVPPMCPVPPACPEPKYRGPLHCLATVARE 172
+PT+V K+R+Q Q+ + G + + ++
Sbjct: 124 ANPTDVLKIRMQAQSNTIQG----------------------------GMIGNFMNIYQQ 155
Query: 173 EGLCGLYKGSSALVLRDGHSFATYFLSYAVLCEWLSPAGHSRPDVPGVLVAGGCAGVLAW 232
EG GL+KG S R Y + + L +G V ++ G+
Sbjct: 156 EGTRGLWKGVSLTAQRAAIVVGVELPVYDITKKHLILSGLMGDTVYTHFLSSFTCGLAGA 215
Query: 233 AVATPMDVIKSRLQ-----ADGQGQRRYRGLLHCMVTSVREEGPRVLFKGLVLNCCRAFP 287
+ P+DV+++R+ DG+ Y G L C++ + + EG L+KG N R P
Sbjct: 216 LASNPVDVVRTRMMNQRVLRDGRCSG-YTGTLDCLLQTWKNEGFFALYKGFWPNWLRLGP 274
Query: 288 VNMVVFVAYEAVLRL 302
N++ FV YE + +L
Sbjct: 275 WNIIFFVTYEQLKKL 289
Score = 47.0 bits (110), Expect = 2e-05
Identities = 48/205 (23%), Positives = 76/205 (37%), Gaps = 28/205 (13%)
Query: 1 MDFVAGAIGGVCGVAVGYPLDTVKVRIQTEPKYT--GIWHCVRDTYHRERVWGFYRGLSL 58
++ + G + GV + P D +K+R+Q + G+ + Y +E G ++G+SL
Sbjct: 108 INVICGILSGVISSTIANPTDVLKIRMQAQSNTIQGGMIGNFMNIYQQEGTRGLWKGVSL 167
Query: 59 PVCTVSLVSSVSFGTYRHCLAHICRLRYGNPDAKPTKADITLSGCASGLVRVFLTSPTEV 118
++V V Y H+ T LS GL ++P +V
Sbjct: 168 TAQRAAIVVGVELPVYDITKKHLILSGLMGD----TVYTHFLSSFTCGLAGALASNPVDV 223
Query: 119 AKVRLQTQTQAQKQQRRLSASGPLAVPPMCPVPPACPEPKYRGPLHCLATVAREEGLCGL 178
+ R+ Q + R SG Y G L CL + EG L
Sbjct: 224 VRTRMMNQ----RVLRDGRCSG------------------YTGTLDCLLQTWKNEGFFAL 261
Query: 179 YKGSSALVLRDGHSFATYFLSYAVL 203
YKG LR G +F++Y L
Sbjct: 262 YKGFWPNWLRLGPWNIIFFVTYEQL 286
>gi|21361114 solute carrier family 25 (mitochondrial carrier;
oxoglutarate carrier), member 11 [Homo sapiens]
Length = 314
Score = 72.8 bits (177), Expect = 4e-13
Identities = 72/303 (23%), Positives = 122/303 (40%), Gaps = 34/303 (11%)
Query: 3 FVAGAIGGVCGVAVGYPLDTVKVRIQTEPK------YTGIWHCVRDTYHRERVWGFYRGL 56
F+ G + G+ PLD VK R+Q + Y +H + E + G Y GL
Sbjct: 25 FLFGGLAGMGATVFVQPLDLVKNRMQLSGEGAKTREYKTSFHALTSILKAEGLRGIYTGL 84
Query: 57 SLPVCTVSLVSSVSFGTYRHCLAHICRLRYGNPDAKPTKADITLSGCASGLVRVFLTSPT 116
S + + ++ G Y + G P KA I ++ A+G F+ +P
Sbjct: 85 SAGLLRQATYTTTRLGIYTVLFERLTGAD-GTPPGFLLKAVIGMTAGATG---AFVGTPA 140
Query: 117 EVAKVRLQTQTQAQKQQRRLSASGPLAVPPMCPVPPACPEPKYRGPLHCLATVAREEGLC 176
EVA +R+ + QRR Y+ + L + REEG+
Sbjct: 141 EVALIRMTADGRLPADQRR----------------------GYKNVFNALIRITREEGVL 178
Query: 177 GLYKGSSALVLRDGHSFATYFLSYAVLCEWLSPAGHSRPDVPGVLVAGGCAGVLAWAVAT 236
L++G + R A SY+ ++L +G+ ++ A +G++ A +
Sbjct: 179 TLWRGCIPTMARAVVVNAAQLASYSQSKQFLLDSGYFSDNILCHFCASMISGLVTTAASM 238
Query: 237 PMDVIKSRLQADG--QGQRRYRGLLHCMVTSVREEGPRVLFKGLVLNCCRAFPVNMVVFV 294
P+D+ K+R+Q G+ Y+ L + VR EG L+KG R P ++ F+
Sbjct: 239 PVDIAKTRIQNMRMIDGKPEYKNGLDVLFKVVRYEGFFSLWKGFTPYYARLGPHTVLTFI 298
Query: 295 AYE 297
E
Sbjct: 299 FLE 301
Score = 72.0 bits (175), Expect = 6e-13
Identities = 60/214 (28%), Positives = 87/214 (40%), Gaps = 29/214 (13%)
Query: 87 GNPDAKPTKADITLSGCASGLVRVFLTSPTEVAKVRLQTQTQAQKQQRRLSASGPLAVPP 146
G P P G A VF+ P ++ K R+Q + K +
Sbjct: 14 GKPRTSPKSVKFLFGGLAGMGATVFV-QPLDLVKNRMQLSGEGAKTR------------- 59
Query: 147 MCPVPPACPEPKYRGPLHCLATVAREEGLCGLYKGSSALVLRDGHSFATYFLSYAVLCEW 206
+Y+ H L ++ + EGL G+Y G SA +LR T Y VL E
Sbjct: 60 -----------EYKTSFHALTSILKAEGLRGIYTGLSAGLLRQATYTTTRLGIYTVLFER 108
Query: 207 LSPAGHSRPDVPGVLVAGGCAGVLAWAVATPMDVIKSRLQADGQ---GQRR-YRGLLHCM 262
L+ A + P V G AG V TP +V R+ ADG+ QRR Y+ + + +
Sbjct: 109 LTGADGTPPGFLLKAVIGMTAGATGAFVGTPAEVALIRMTADGRLPADQRRGYKNVFNAL 168
Query: 263 VTSVREEGPRVLFKGLVLNCCRAFPVNMVVFVAY 296
+ REEG L++G + RA VN +Y
Sbjct: 169 IRITREEGVLTLWRGCIPTMARAVVVNAAQLASY 202
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.325 0.139 0.450
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 12,843,684
Number of Sequences: 37866
Number of extensions: 607417
Number of successful extensions: 4222
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 71
Number of HSP's successfully gapped in prelim test: 32
Number of HSP's that attempted gapping in prelim test: 3471
Number of HSP's gapped (non-prelim): 340
length of query: 308
length of database: 18,247,518
effective HSP length: 102
effective length of query: 206
effective length of database: 14,385,186
effective search space: 2963348316
effective search space used: 2963348316
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.