Search of human proteins with 46255030

Search of human proteins with 46255030

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|46255030 family with sequence similarity 3, member B isoform
a [Homo sapiens]
         (235 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|46255030 family with sequence similarity 3, member B isoform ...   479   e-136
gi|46255032 family with sequence similarity 3, member B isoform ...   379   e-105
gi|91807125 family with sequence similarity 3, member C precurso...   149   2e-36
gi|7661714 family with sequence similarity 3, member C precursor...   149   2e-36
gi|13324682 family 3, member A protein [Homo sapiens]                 140   7e-34
gi|20270363 family with sequence similarity 3, member D [Homo sa...   134   7e-32
gi|210147552 O-linked mannose beta1,2-N-acetylglucosaminyltransf...    64   9e-11
gi|38638698 KIAA1199 [Homo sapiens]                                    49   5e-06
gi|209447096 transmembrane protein 2 isoform b [Homo sapiens]          37   0.011
gi|7019555 transmembrane protein 2 isoform a [Homo sapiens]            37   0.011
gi|223633991 vanin 1 precursor [Homo sapiens]                          30   2.3  
gi|154689780 son of sevenless homolog 2 [Homo sapiens]                 28   8.9  

>gi|46255030 family with sequence similarity 3, member B isoform a
           [Homo sapiens]
          Length = 235

 Score =  479 bits (1234), Expect = e-136
 Identities = 235/235 (100%), Positives = 235/235 (100%)

Query: 1   MRPLAGGLLKVVFVVFASLCAWYSGYLLAELIPDAPLSSAAYSIRSIGERPVLKAPVPKR 60
           MRPLAGGLLKVVFVVFASLCAWYSGYLLAELIPDAPLSSAAYSIRSIGERPVLKAPVPKR
Sbjct: 1   MRPLAGGLLKVVFVVFASLCAWYSGYLLAELIPDAPLSSAAYSIRSIGERPVLKAPVPKR 60

Query: 61  QKCDHWTPCPSDTYAYRLLSGGGRSKYAKICFEDNLLMGEQLGNVARGINIAIVNYVTGN 120
           QKCDHWTPCPSDTYAYRLLSGGGRSKYAKICFEDNLLMGEQLGNVARGINIAIVNYVTGN
Sbjct: 61  QKCDHWTPCPSDTYAYRLLSGGGRSKYAKICFEDNLLMGEQLGNVARGINIAIVNYVTGN 120

Query: 121 VTATRCFDMYEGDNSGPMTKFIQSAAPKSLLFMVTYDDGSTRLNNDAKNAIEALGSKEIR 180
           VTATRCFDMYEGDNSGPMTKFIQSAAPKSLLFMVTYDDGSTRLNNDAKNAIEALGSKEIR
Sbjct: 121 VTATRCFDMYEGDNSGPMTKFIQSAAPKSLLFMVTYDDGSTRLNNDAKNAIEALGSKEIR 180

Query: 181 NMKFRSSWVFIAAKGLELPSEIQREKINHSDAKNNRYSGWPAEIQIEGCIPKERS 235
           NMKFRSSWVFIAAKGLELPSEIQREKINHSDAKNNRYSGWPAEIQIEGCIPKERS
Sbjct: 181 NMKFRSSWVFIAAKGLELPSEIQREKINHSDAKNNRYSGWPAEIQIEGCIPKERS 235


>gi|46255032 family with sequence similarity 3, member B isoform b
           [Homo sapiens]
          Length = 187

 Score =  379 bits (973), Expect = e-105
 Identities = 183/186 (98%), Positives = 184/186 (98%)

Query: 50  RPVLKAPVPKRQKCDHWTPCPSDTYAYRLLSGGGRSKYAKICFEDNLLMGEQLGNVARGI 109
           RP+  APVPKRQKCDHWTPCPSDTYAYRLLSGGGRSKYAKICFEDNLLMGEQLGNVARGI
Sbjct: 2   RPLAGAPVPKRQKCDHWTPCPSDTYAYRLLSGGGRSKYAKICFEDNLLMGEQLGNVARGI 61

Query: 110 NIAIVNYVTGNVTATRCFDMYEGDNSGPMTKFIQSAAPKSLLFMVTYDDGSTRLNNDAKN 169
           NIAIVNYVTGNVTATRCFDMYEGDNSGPMTKFIQSAAPKSLLFMVTYDDGSTRLNNDAKN
Sbjct: 62  NIAIVNYVTGNVTATRCFDMYEGDNSGPMTKFIQSAAPKSLLFMVTYDDGSTRLNNDAKN 121

Query: 170 AIEALGSKEIRNMKFRSSWVFIAAKGLELPSEIQREKINHSDAKNNRYSGWPAEIQIEGC 229
           AIEALGSKEIRNMKFRSSWVFIAAKGLELPSEIQREKINHSDAKNNRYSGWPAEIQIEGC
Sbjct: 122 AIEALGSKEIRNMKFRSSWVFIAAKGLELPSEIQREKINHSDAKNNRYSGWPAEIQIEGC 181

Query: 230 IPKERS 235
           IPKERS
Sbjct: 182 IPKERS 187


>gi|91807125 family with sequence similarity 3, member C precursor
           [Homo sapiens]
          Length = 227

 Score =  149 bits (377), Expect = 2e-36
 Identities = 85/229 (37%), Positives = 126/229 (55%), Gaps = 8/229 (3%)

Query: 7   GLLKVVFVVFASLCAWYSGYLLAELIPDAPLSSA-AYSIRSIGERPVLKAPVPKRQKCDH 65
           G  K+V  V   L  +Y    + E+  DA L +  A S      R    +  P R KC  
Sbjct: 5   GAAKLVVAVAVFLLTFYVISQVFEIKMDASLGNLFARSALDTAAR----STKPPRYKCGI 60

Query: 66  WTPCPSDTYAYRLLSGGGRSKYAKICFEDNLLMGEQLGNVARGINIAIVNYVTGNVTATR 125
              CP   +A+++ SG       KIC EDN+LM     NV RGIN+A+ N  TG V  T+
Sbjct: 61  SKACPEKHFAFKMASGAANVVGPKICLEDNVLMSGVKNNVGRGINVALANGKTGEVLDTK 120

Query: 126 CFDMYEGDNSGPMTKFIQSAAPKSLLFMVTYDDGSTRLNNDAKNAIEALGSKEIRNMKFR 185
            FDM+ GD   P  +F+++    +++ M TYDDG+T+LN++A+  I  LGS  I N+ FR
Sbjct: 121 YFDMWGGD-VAPFIEFLKAIQDGTIVLMGTYDDGATKLNDEARRLIADLGSTSITNLGFR 179

Query: 186 SSWVFIAAKGLELPSEIQREKINHSDAKNNRYSGWPAEIQIEGCIPKER 234
            +WVF   KG++  S  ++   N+ D   N+Y GWP  +++EGCIP+++
Sbjct: 180 DNWVFCGGKGIKTKSPFEQHIKNNKD--TNKYEGWPEVVEMEGCIPQKQ 226


>gi|7661714 family with sequence similarity 3, member C precursor
           [Homo sapiens]
          Length = 227

 Score =  149 bits (377), Expect = 2e-36
 Identities = 85/229 (37%), Positives = 126/229 (55%), Gaps = 8/229 (3%)

Query: 7   GLLKVVFVVFASLCAWYSGYLLAELIPDAPLSSA-AYSIRSIGERPVLKAPVPKRQKCDH 65
           G  K+V  V   L  +Y    + E+  DA L +  A S      R    +  P R KC  
Sbjct: 5   GAAKLVVAVAVFLLTFYVISQVFEIKMDASLGNLFARSALDTAAR----STKPPRYKCGI 60

Query: 66  WTPCPSDTYAYRLLSGGGRSKYAKICFEDNLLMGEQLGNVARGINIAIVNYVTGNVTATR 125
              CP   +A+++ SG       KIC EDN+LM     NV RGIN+A+ N  TG V  T+
Sbjct: 61  SKACPEKHFAFKMASGAANVVGPKICLEDNVLMSGVKNNVGRGINVALANGKTGEVLDTK 120

Query: 126 CFDMYEGDNSGPMTKFIQSAAPKSLLFMVTYDDGSTRLNNDAKNAIEALGSKEIRNMKFR 185
            FDM+ GD   P  +F+++    +++ M TYDDG+T+LN++A+  I  LGS  I N+ FR
Sbjct: 121 YFDMWGGD-VAPFIEFLKAIQDGTIVLMGTYDDGATKLNDEARRLIADLGSTSITNLGFR 179

Query: 186 SSWVFIAAKGLELPSEIQREKINHSDAKNNRYSGWPAEIQIEGCIPKER 234
            +WVF   KG++  S  ++   N+ D   N+Y GWP  +++EGCIP+++
Sbjct: 180 DNWVFCGGKGIKTKSPFEQHIKNNKD--TNKYEGWPEVVEMEGCIPQKQ 226


>gi|13324682 family 3, member A protein [Homo sapiens]
          Length = 230

 Score =  140 bits (354), Expect = 7e-34
 Identities = 80/231 (34%), Positives = 125/231 (54%), Gaps = 10/231 (4%)

Query: 4   LAGGLLKVVFVVFASLCAWYSGYLLAELIPDAPLSS--AAYSIRSIGERPVLKAPVPKRQ 61
           LAG L  VV VV   +      +++  ++   P S       + +  E  V  AP  ++ 
Sbjct: 3   LAGPLRIVVLVVSVGVT-----WIVVSILLGGPGSGFPRIQQLFTSPESSVTAAPRARKY 57

Query: 62  KCDHWTPCPSDTYAYRLLSGGGRSKYAKICFEDNLLMGEQLGNVARGINIAIVNYVTGNV 121
           KC    PCP +  A+R++SG       KIC ED +LM     NV RG+NIA+VN V+G +
Sbjct: 58  KCGLPQPCPEEHLAFRVVSGAANVIGPKICLEDKMLMSSVKDNVGRGLNIALVNGVSGEL 117

Query: 122 TATRCFDMYEGDNSGPMTKFIQSAAPKSLLFMVTYDDGSTRLNNDAKNAIEALGSKEIRN 181
              R FDM+ GD    + KFI+     +L+F+ +YDD +T++N + +     LGS+  + 
Sbjct: 118 IEARAFDMWAGD-VNDLLKFIRPLHEGTLVFVASYDDPATKMNEETRKLFSELGSRNAKE 176

Query: 182 MKFRSSWVFIAAKGLELPSEIQREKINHSDAKNNRYSGWPAEIQIEGCIPK 232
           + FR SWVF+ AKG++  S  ++   N     +N+Y G P  +++EGCIP+
Sbjct: 177 LAFRDSWVFVGAKGVQNKSPFEQHVKN--SKHSNKYEGCPEALEMEGCIPR 225


>gi|20270363 family with sequence similarity 3, member D [Homo
           sapiens]
          Length = 224

 Score =  134 bits (337), Expect = 7e-32
 Identities = 75/228 (32%), Positives = 124/228 (54%), Gaps = 15/228 (6%)

Query: 7   GLLKVVFVVFASLCAWYSGYLLAELIPDAPLSSAAYSIRS---IGERPVLKAPVPKRQKC 63
           G+L+++ ++FA +  W        +   + +S +  +IR    +   P  +  V K+ KC
Sbjct: 5   GVLRLLALIFAIVTTW--------MFIRSYMSFSMKTIRLPRWLAASPTKEIQV-KKYKC 55

Query: 64  DHWTPCPSDTYAYRLLSGGGRSKYAKICFEDNLLMGEQLGNVARGINIAIVNYVTGNVTA 123
               PCP++ +A+++ SG        +CFED ++M     NV RG+NIA+VN  TG V  
Sbjct: 56  GLIKPCPANYFAFKICSGAANVVGPTMCFEDRMIMSPVKNNVGRGLNIALVNGTTGAVLG 115

Query: 124 TRCFDMYEGDNSGPMTKFIQSAAPKSLLFMVTYDDGSTRLNNDAKNAIEALGSKEIRNMK 183
            + FDMY GD    + KF++     +L+ + +YDD  T++N++++     LGS   + + 
Sbjct: 116 QKAFDMYSGDVM-HLVKFLKEIPGGALVLVASYDDPGTKMNDESRKLFSDLGSSYAKQLG 174

Query: 184 FRSSWVFIAAKGLELPSEIQREKINHSDAKNNRYSGWPAEIQIEGCIP 231
           FR SWVFI AK L   S  ++   N  D   N+Y GWP  +++EGC+P
Sbjct: 175 FRDSWVFIGAKDLRGKSPFEQFLKNSPD--TNKYEGWPELLEMEGCMP 220


>gi|210147552 O-linked mannose
           beta1,2-N-acetylglucosaminyltransferase [Homo sapiens]
          Length = 660

 Score = 64.3 bits (155), Expect = 9e-11
 Identities = 31/106 (29%), Positives = 53/106 (50%)

Query: 90  ICFEDNLLMGEQLGNVARGINIAIVNYVTGNVTATRCFDMYEGDNSGPMTKFIQSAAPKS 149
           +  +   ++ ++     RGI++ ++N  TG+V A R FD Y       M  F+   AP  
Sbjct: 112 VAVDGTTVLEDEAREQGRGIHVIVLNQATGHVMAKRVFDTYSPHEDEAMVLFLNMVAPGR 171

Query: 150 LLFMVTYDDGSTRLNNDAKNAIEALGSKEIRNMKFRSSWVFIAAKG 195
           +L     D+GS  L + AK  + +LGS+    + +R +W F+  KG
Sbjct: 172 VLICTVKDEGSFHLKDTAKALLRSLGSQAGPALGWRDTWAFVGRKG 217


>gi|38638698 KIAA1199 [Homo sapiens]
          Length = 1361

 Score = 48.5 bits (114), Expect = 5e-06
 Identities = 25/90 (27%), Positives = 47/90 (52%), Gaps = 1/90 (1%)

Query: 107 RGINIAIVNYVTGNVTATRCFDMYEGDN-SGPMTKFIQSAAPKSLLFMVTYDDGSTRLNN 165
           RG+ + +++  +G V  +  FD Y     S  + +++ +     +L +   D+GS  L++
Sbjct: 187 RGVIVHVIDPKSGTVIHSDRFDTYRSKKESERLVQYLNAVPDGRILSVAVNDEGSRNLDD 246

Query: 166 DAKNAIEALGSKEIRNMKFRSSWVFIAAKG 195
            A+ A+  LGSK   ++ FR  W F+  KG
Sbjct: 247 MARKAMTKLGSKHFLHLGFRHPWSFLTVKG 276


>gi|209447096 transmembrane protein 2 isoform b [Homo sapiens]
          Length = 1320

 Score = 37.4 bits (85), Expect = 0.011
 Identities = 27/109 (24%), Positives = 51/109 (46%), Gaps = 4/109 (3%)

Query: 106 ARGINIAIVNYVTGNVTATRCFDMYEGDN-SGPMTKFIQSAAPKSLLFMVTYDDGSTRLN 164
           +RG+N+ +++  T  +  +  FD +E  N S  + +F++   P  ++ +   D  +  L 
Sbjct: 264 SRGLNVRVIDQDTAKILESERFDTHEYRNESRRLQEFLRFQDPGRIVAIAVGDSAAKSLL 323

Query: 165 NDAKNAI-EALGSKEIRNMKFRSSWVFIAA--KGLELPSEIQREKINHS 210
                 I E LGS+ I+ + +R +W  +     G    +E  R   NHS
Sbjct: 324 QGTIQMIQERLGSELIQGLGYRQAWALVGVIDGGSTSCNESVRNYENHS 372


>gi|7019555 transmembrane protein 2 isoform a [Homo sapiens]
          Length = 1383

 Score = 37.4 bits (85), Expect = 0.011
 Identities = 27/109 (24%), Positives = 51/109 (46%), Gaps = 4/109 (3%)

Query: 106 ARGINIAIVNYVTGNVTATRCFDMYEGDN-SGPMTKFIQSAAPKSLLFMVTYDDGSTRLN 164
           +RG+N+ +++  T  +  +  FD +E  N S  + +F++   P  ++ +   D  +  L 
Sbjct: 264 SRGLNVRVIDQDTAKILESERFDTHEYRNESRRLQEFLRFQDPGRIVAIAVGDSAAKSLL 323

Query: 165 NDAKNAI-EALGSKEIRNMKFRSSWVFIAA--KGLELPSEIQREKINHS 210
                 I E LGS+ I+ + +R +W  +     G    +E  R   NHS
Sbjct: 324 QGTIQMIQERLGSELIQGLGYRQAWALVGVIDGGSTSCNESVRNYENHS 372


>gi|223633991 vanin 1 precursor [Homo sapiens]
          Length = 513

 Score = 29.6 bits (65), Expect = 2.3
 Identities = 25/89 (28%), Positives = 36/89 (40%), Gaps = 3/89 (3%)

Query: 55  APVPKRQKCDHWTP-CPSD-TYAYRL-LSGGGRSKYAKICFEDNLLMGEQLGNVARGINI 111
           A +  ++ CD   P CP D  Y Y   +    + K      + NL MGE   NV +   I
Sbjct: 137 ANIGDKKPCDTSDPQCPPDGRYQYNTDVVFDSQGKLVARYHKQNLFMGENQFNVPKEPEI 196

Query: 112 AIVNYVTGNVTATRCFDMYEGDNSGPMTK 140
              N   G+     CFD+   D +  + K
Sbjct: 197 VTFNTTFGSFGIFTCFDILFHDPAVTLVK 225


>gi|154689780 son of sevenless homolog 2 [Homo sapiens]
          Length = 1332

 Score = 27.7 bits (60), Expect = 8.9
 Identities = 10/27 (37%), Positives = 17/27 (62%)

Query: 39   SAAYSIRSIGERPVLKAPVPKRQKCDH 65
            S+  S+  + E P++  P+P R+K DH
Sbjct: 1131 SSCGSLHKLSEEPLIPPPLPPRKKFDH 1157


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.319    0.135    0.410 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 8,810,501
Number of Sequences: 37866
Number of extensions: 382216
Number of successful extensions: 738
Number of sequences better than 10.0: 12
Number of HSP's better than 10.0 without gapping: 9
Number of HSP's successfully gapped in prelim test: 3
Number of HSP's that attempted gapping in prelim test: 718
Number of HSP's gapped (non-prelim): 12
length of query: 235
length of database: 18,247,518
effective HSP length: 99
effective length of query: 136
effective length of database: 14,498,784
effective search space: 1971834624
effective search space used: 1971834624
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 60 (27.7 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.