BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|46094072 zinc finger protein 770 [Homo sapiens] (691 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|46094072 zinc finger protein 770 [Homo sapiens] 1449 0.0 gi|122937213 zinc finger protein 99 [Homo sapiens] 253 3e-67 gi|239757212 PREDICTED: similar to hCG1773661 [Homo sapiens] 251 2e-66 gi|239751718 PREDICTED: similar to hCG1773661 [Homo sapiens] 251 2e-66 gi|239746221 PREDICTED: hypothetical protein XP_002343677 [Homo ... 251 2e-66 gi|118600985 zinc finger protein 91 [Homo sapiens] 245 1e-64 gi|210031219 zinc finger protein 845 [Homo sapiens] 226 4e-59 gi|172072608 zinc finger protein 624 [Homo sapiens] 222 8e-58 gi|156627573 zinc finger protein 836 [Homo sapiens] 222 1e-57 gi|54291708 zinc finger protein 780B [Homo sapiens] 220 4e-57 gi|119120877 zinc finger protein 721 [Homo sapiens] 219 5e-57 gi|150378520 zinc finger protein 594 [Homo sapiens] 219 9e-57 gi|6005976 zinc finger protein 208 [Homo sapiens] 218 1e-56 gi|194018469 zinc finger protein 546 [Homo sapiens] 214 2e-55 gi|157167158 zinc finger protein 808 [Homo sapiens] 214 3e-55 gi|40217792 zinc finger protein 585A [Homo sapiens] 209 7e-54 gi|22749331 zinc finger protein 585A [Homo sapiens] 209 7e-54 gi|49574543 zinc finger protein 616 [Homo sapiens] 209 9e-54 gi|154800445 zinc finger protein 62 homolog [Homo sapiens] 207 3e-53 gi|115511042 zinc finger protein 493 isoform 1 [Homo sapiens] 207 3e-53 gi|115511044 zinc finger protein 493 isoform 3 [Homo sapiens] 207 3e-53 gi|211057416 zinc finger protein 841 [Homo sapiens] 206 8e-53 gi|47271464 zinc finger protein 607 [Homo sapiens] 206 8e-53 gi|222418585 zinc finger protein 814 [Homo sapiens] 203 5e-52 gi|62243640 zinc finger protein 107 [Homo sapiens] 202 6e-52 gi|7706775 zinc finger protein 107 [Homo sapiens] 202 6e-52 gi|11386193 zinc finger protein 197 isoform 1 [Homo sapiens] 202 6e-52 gi|55769537 zinc finger protein 658 [Homo sapiens] 201 2e-51 gi|68303809 zinc finger protein 43 [Homo sapiens] 199 7e-51 gi|14211907 zinc finger protein 347 [Homo sapiens] 199 7e-51 >gi|46094072 zinc finger protein 770 [Homo sapiens] Length = 691 Score = 1449 bits (3750), Expect = 0.0 Identities = 691/691 (100%), Positives = 691/691 (100%) Query: 1 MMAENNLKMLKIQQCVVANKLPRNRPYVCNICFKHFETPSKLARHYLIHTGQKPFECDVC 60 MMAENNLKMLKIQQCVVANKLPRNRPYVCNICFKHFETPSKLARHYLIHTGQKPFECDVC Sbjct: 1 MMAENNLKMLKIQQCVVANKLPRNRPYVCNICFKHFETPSKLARHYLIHTGQKPFECDVC 60 Query: 61 HKTFRQLVHLERHQLTHSLPFKCSICQRHFKNLKTFVKHQQLHNETYQNNVKQVRRLLEA 120 HKTFRQLVHLERHQLTHSLPFKCSICQRHFKNLKTFVKHQQLHNETYQNNVKQVRRLLEA Sbjct: 61 HKTFRQLVHLERHQLTHSLPFKCSICQRHFKNLKTFVKHQQLHNETYQNNVKQVRRLLEA 120 Query: 121 KQEKSMYGVYNTFTTEERWALHPCSKSDPMYSMKRRKNIHACTICGKMFPSQSKLDRHVL 180 KQEKSMYGVYNTFTTEERWALHPCSKSDPMYSMKRRKNIHACTICGKMFPSQSKLDRHVL Sbjct: 121 KQEKSMYGVYNTFTTEERWALHPCSKSDPMYSMKRRKNIHACTICGKMFPSQSKLDRHVL 180 Query: 181 IHTGQRPFKCVLCTKSFRQSTHLKIHQLTHSEERPFQCCFCQKGFKIQSKLLKHKQIHTR 240 IHTGQRPFKCVLCTKSFRQSTHLKIHQLTHSEERPFQCCFCQKGFKIQSKLLKHKQIHTR Sbjct: 181 IHTGQRPFKCVLCTKSFRQSTHLKIHQLTHSEERPFQCCFCQKGFKIQSKLLKHKQIHTR 240 Query: 241 NKAFRALLLKKRRTESRPLPNKLNANQGGFENGEIGESEENNPLDVHSIYIVPFQCPKCE 300 NKAFRALLLKKRRTESRPLPNKLNANQGGFENGEIGESEENNPLDVHSIYIVPFQCPKCE Sbjct: 241 NKAFRALLLKKRRTESRPLPNKLNANQGGFENGEIGESEENNPLDVHSIYIVPFQCPKCE 300 Query: 301 KCFESEQILNEHSCFAARSGKIPSRFKRSYNYKTIVKKILAKLKRARSKKLDNFQSEKKV 360 KCFESEQILNEHSCFAARSGKIPSRFKRSYNYKTIVKKILAKLKRARSKKLDNFQSEKKV Sbjct: 301 KCFESEQILNEHSCFAARSGKIPSRFKRSYNYKTIVKKILAKLKRARSKKLDNFQSEKKV 360 Query: 361 FKKSFLRNCDLISGEQSSEQTQRTFVGSLGKHGTYKTIGNRKKKTLTLPFSWQNMGKNLK 420 FKKSFLRNCDLISGEQSSEQTQRTFVGSLGKHGTYKTIGNRKKKTLTLPFSWQNMGKNLK Sbjct: 361 FKKSFLRNCDLISGEQSSEQTQRTFVGSLGKHGTYKTIGNRKKKTLTLPFSWQNMGKNLK 420 Query: 421 GILTTENILSIDNSVNKKDLSICGSSGEEFFNNCEVLQCGFSVPRENIRTRHKICPCDKC 480 GILTTENILSIDNSVNKKDLSICGSSGEEFFNNCEVLQCGFSVPRENIRTRHKICPCDKC Sbjct: 421 GILTTENILSIDNSVNKKDLSICGSSGEEFFNNCEVLQCGFSVPRENIRTRHKICPCDKC 480 Query: 481 EKVFPSISKLKRHYLIHTGQRPFGCNICGKSFRQSAHLKRHEQTHNEKSPYASLCQVEFG 540 EKVFPSISKLKRHYLIHTGQRPFGCNICGKSFRQSAHLKRHEQTHNEKSPYASLCQVEFG Sbjct: 481 EKVFPSISKLKRHYLIHTGQRPFGCNICGKSFRQSAHLKRHEQTHNEKSPYASLCQVEFG 540 Query: 541 NFNNLSNHSGNNVNYNASQQCQAPGVQKYEVSESDQMSGVKAESQDFIPGSTGQPCLPNV 600 NFNNLSNHSGNNVNYNASQQCQAPGVQKYEVSESDQMSGVKAESQDFIPGSTGQPCLPNV Sbjct: 541 NFNNLSNHSGNNVNYNASQQCQAPGVQKYEVSESDQMSGVKAESQDFIPGSTGQPCLPNV 600 Query: 601 LLESEQSNPFCSYSEHQEKNDVFLYRCSVCAKSFRSPSKLERHYLIHAGQKPFECSVCGK 660 LLESEQSNPFCSYSEHQEKNDVFLYRCSVCAKSFRSPSKLERHYLIHAGQKPFECSVCGK Sbjct: 601 LLESEQSNPFCSYSEHQEKNDVFLYRCSVCAKSFRSPSKLERHYLIHAGQKPFECSVCGK 660 Query: 661 TFRQAPHWKRHQLTHFKERPQGKVVALDSVM 691 TFRQAPHWKRHQLTHFKERPQGKVVALDSVM Sbjct: 661 TFRQAPHWKRHQLTHFKERPQGKVVALDSVM 691 >gi|122937213 zinc finger protein 99 [Homo sapiens] Length = 1036 Score = 253 bits (647), Expect = 3e-67 Identities = 193/712 (27%), Positives = 311/712 (43%), Gaps = 88/712 (12%) Query: 3 AENNLKMLKIQQCVVANKLPRNRPYVCNICFKHFETPSKLARHYLIHTGQKPFECDVCHK 62 A +NL L+ + + + +PY C C K F+ SKL H +IHT +KP +C+ C K Sbjct: 286 AFSNLSALRKHEIIHTGQ----KPYKCEECGKAFKWSSKLTVHKVIHTAEKPCKCEECGK 341 Query: 63 TFRQLVHLERHQLTHS--LPFKCSICQRHFKNLKTFVKHQQLHNETYQNNVKQVRRLLEA 120 F++ L +H++ H+ P+KC C + F N KH+ +H ++ + + Sbjct: 342 AFKRFSALRKHKIIHTGKQPYKCEECSKAFSNFSALRKHEIIHTGEKPYKCEECGKAFKW 401 Query: 121 KQEKSMYGVYNTFTTEERWALHPCSKSDPMYS-MKRRKNIHA------CTICGKMFPSQS 173 + +++ V + E+ C K+ +S +++ K IH C CGK F + S Sbjct: 402 SSKLTVHKVIHM--EEKPCKCEECGKAFKHFSALRKHKIIHTGKKPYKCEECGKAFNNSS 459 Query: 174 KLDRHVLIHTGQRPFKCVLCTKSFRQSTHLKIHQLTHSEERPFQCCFCQKGFKIQSKLLK 233 L +H +IHTG++P+KC C K+F+QS+HL H+ H+ E+P++C C K F S L K Sbjct: 460 TLMKHKIIHTGKKPYKCEECGKAFKQSSHLTRHKAIHTGEKPYKCEECGKAFNHFSALRK 519 Query: 234 HKQIHTRNKAFRALLLKKRRTESRPLPNKLNANQGGFENGEIGESEENNPLDVHSIYIVP 293 H+ IHT K ++ K ++S L EI + E P Sbjct: 520 HQIIHTGKKPYKCEECGKAFSQSSTL-----------RKHEIIHTGEK-----------P 557 Query: 294 FQCPKCEKCFESEQILNEHSCFAARSGKIP-SRFKRSYNYKTIVKKILAKLKRARSKKLD 352 ++C +C K F+ L H +++N+ + ++K K+ K Sbjct: 558 YKCEECGKAFKWSSHLTRHKVIHTEEKPYKCEECGKAFNHFSALRK--HKIIHTGKKPYK 615 Query: 353 NFQSEKKVFKKSFLRNCDLI-SGEQ--SSEQTQRTFVGSLGKHGTYKTIGNRKKKTLTLP 409 + K + S LR ++I +GE+ E+ + F S K +K I +K P Sbjct: 616 CEECGKAFSQSSTLRKHEIIHTGEKPYKCEECGKAFKWS-SKLTVHKVIHTAEK-----P 669 Query: 410 FSWQNMGKNLKGILTTENILSIDNSVNKKDLSICGSSGEEFFNNCEVL------------ 457 + GK K I CG + FNN L Sbjct: 670 CKCEECGKAFKHFSALRKHKIIHTGKKPYKCEECGKA----FNNSSTLRKHEIIHTGEKS 725 Query: 458 ----QCGFSVPRENIRTRHKICPCDKCEKVFPSISKLKRHYLIHTGQRPFGCNICGKSFR 513 +C E I T K C++C K F + S L++H +I+TG++P+ C CGK+F+ Sbjct: 726 YKCEECALR-KHEIIHTGKKPYKCEECGKAFNNSSTLRKHKIIYTGKKPYKCEECGKAFK 784 Query: 514 QSAHLKRHEQTHNEKSPY-ASLCQVEFGNFNNLSNHSGNNVNYNASQQCQAPGVQKYEVS 572 QS+HL RH+ H + PY C F N + L H + S +C+ G S Sbjct: 785 QSSHLTRHKAVHTGEKPYKCGECGKAFNNSSTLKKHKLIHTR-EKSYKCEECGKAFSNFS 843 Query: 573 ESDQMSGVKAESQDFIPGSTGQPCLPNVLLESEQSNPFCSYSEHQEKNDVFL----YRCS 628 + + TG+ P E E F + S + + Y+C Sbjct: 844 ALRKHKIIH----------TGEK--PYKCEECECGKAFNNSSTLMKHKIIHTGEKPYKCE 891 Query: 629 VCAKSFRSPSKLERHYLIHAGQKPFECSVCGKTFRQAPHWKRHQLTHFKERP 680 C K F + S L +H +IH G+KP++C CGK F+Q+ H +H+ H E+P Sbjct: 892 ECGKGFNNFSTLMKHKIIHTGEKPYKCEECGKAFKQSSHLTKHKSIHTGEKP 943 Score = 249 bits (635), Expect = 8e-66 Identities = 187/700 (26%), Positives = 308/700 (44%), Gaps = 95/700 (13%) Query: 25 RPYVCNICFKHFETPSKLARHYLIHTGQKPFECDVCHKTFRQLVHLERHQLTHS--LPFK 82 +PY C C K F+ SKL H +IH +KP +C+ C K F+ L +H++ H+ P+K Sbjct: 388 KPYKCEECGKAFKWSSKLTVHKVIHMEEKPCKCEECGKAFKHFSALRKHKIIHTGKKPYK 447 Query: 83 CSICQRHFKNLKTFVKHQQLHNETYQNNVKQVRRLLEAKQEKSMYGVYNTFTTEERWALH 142 C C + F N T +KH+ +H ++ + + + + +T E+ + Sbjct: 448 CEECGKAFNNSSTLMKHKIIHTGKKPYKCEECGKAFKQSSHLTRHKAIHT--GEKPYKCE 505 Query: 143 PCSKSDPMYSMKRRKNI-------HACTICGKMFPSQSKLDRHVLIHTGQRPFKCVLCTK 195 C K+ +S R+ I + C CGK F S L +H +IHTG++P+KC C K Sbjct: 506 ECGKAFNHFSALRKHQIIHTGKKPYKCEECGKAFSQSSTLRKHEIIHTGEKPYKCEECGK 565 Query: 196 SFRQSTHLKIHQLTHSEERPFQCCFCQKGFKIQSKLLKHKQIHTRNKAFRALLLKKRRTE 255 +F+ S+HL H++ H+EE+P++C C K F S L KHK IHT K ++ K ++ Sbjct: 566 AFKWSSHLTRHKVIHTEEKPYKCEECGKAFNHFSALRKHKIIHTGKKPYKCEECGKAFSQ 625 Query: 256 SRPLPNK--LNANQGGFENGEIGESEE-NNPLDVHSIYIV---PFQCPKCEKCFESEQIL 309 S L ++ + ++ E G++ + ++ L VH + P +C +C K F+ L Sbjct: 626 SSTLRKHEIIHTGEKPYKCEECGKAFKWSSKLTVHKVIHTAEKPCKCEECGKAFKHFSAL 685 Query: 310 NEHSCFAARSGKIPSRFK---RSYNYKTIVKKILA--------KLKRARSKKLDNFQSEK 358 +H +GK P + + +++N + ++K K + +K + + K Sbjct: 686 RKHKII--HTGKKPYKCEECGKAFNNSSTLRKHEIIHTGEKSYKCEECALRKHEIIHTGK 743 Query: 359 KVFKKSFLRNCDLISGEQSSEQTQRTFVGSLGKHGTYKTIGNRKKKTLTLPFSWQNMGKN 418 K +K C+ ++ T R KH K I KK P+ + GK Sbjct: 744 KPYK------CEECGKAFNNSSTLR-------KH---KIIYTGKK-----PYKCEECGKA 782 Query: 419 LK--GILTTENILSIDNSVNKKDLSICGSSGEEFFNNCEVLQCGFSVPRENIRTRHKICP 476 K LT + K CG G+ F NN L+ + I TR K Sbjct: 783 FKQSSHLTRHKAVHTGEKPYK-----CGECGKAF-NNSSTLK-----KHKLIHTREKSYK 831 Query: 477 CDKCEKVFPSISKLKRHYLIHTGQRPFGCNIC--GKSFRQSAHLKRHEQTHNEKSPY-AS 533 C++C K F + S L++H +IHTG++P+ C C GK+F S+ L +H+ H + PY Sbjct: 832 CEECGKAFSNFSALRKHKIIHTGEKPYKCEECECGKAFNNSSTLMKHKIIHTGEKPYKCE 891 Query: 534 LCQVEFGNFNNLSNHSGNNVNYNASQQCQAPGVQKYEVSESDQMSGVKAESQDFIPGSTG 593 C F NF+ L H + +C+ E ++ + S + + G Sbjct: 892 ECGKGFNNFSTLMKHKIIHTG-EKPYKCE-------ECGKAFKQSSHLTKHKSIHTGEKP 943 Query: 594 QPCLPNVLLESEQSNPFCSYSEHQEKNDVFL-------------YRCSVCAKSFRSPSKL 640 C E+ F +S + + Y+C C K+F S L Sbjct: 944 YKC-------EERGKAFSHFSRLTKHRIIHTGKKPYKCEECEKPYKCEECGKAFNQSSHL 996 Query: 641 ERHYLIHAGQKPFECSVCGKTFRQAPHWKRHQLTHFKERP 680 +H IH G K ++C CGK F +H++ H E+P Sbjct: 997 TQHKTIHTGGKTYKCEECGKAFNHLSALTKHKIIHTGEKP 1036 Score = 239 bits (609), Expect = 8e-63 Identities = 194/709 (27%), Positives = 328/709 (46%), Gaps = 99/709 (13%) Query: 11 KIQQCVVANKLPRNRPYVCNICFKHFETPSKLARHYLIHTGQKPFECDVCHKTFRQLVHL 70 K+ QC + + + CN K F S R+ +IHTG+KP++C+ C K F+Q HL Sbjct: 153 KLNQCWTTTQ---GKIFQCNKYVKVFHKYSNSNRYKIIHTGKKPYKCEECGKAFKQSSHL 209 Query: 71 ERHQLTHS--LPFKCSICQRHFKNLKTFVKHQQLHNETYQNNVKQVRRLLEAKQEKSMYG 128 RH+ H+ P+KC C + F + KHQ +H ++ + A + S Sbjct: 210 TRHKAIHTGEKPYKCEECGKAFNHFSALRKHQIIHTGKKPYKCEECGK---AFSQSSTLR 266 Query: 129 VYNTFTTEERWALHPCSKSDPMYSMKRRKNIHACTICGKMFPSQSKLDRHVLIHTGQRPF 188 + TEE+ P + CGK F + S L +H +IHTGQ+P+ Sbjct: 267 KHEIIHTEEK----PYKYEE----------------CGKAFSNLSALRKHEIIHTGQKPY 306 Query: 189 KCVLCTKSFRQSTHLKIHQLTHSEERPFQCCFCQKGFKIQSKLLKHKQIHTRNKAFRALL 248 KC C K+F+ S+ L +H++ H+ E+P +C C K FK S L KHK IHT + ++ Sbjct: 307 KCEECGKAFKWSSKLTVHKVIHTAEKPCKCEECGKAFKRFSALRKHKIIHTGKQPYKCEE 366 Query: 249 LKKRRTESRPLPNK--LNANQGGFENGEIGES-EENNPLDVHSIYIV---PFQCPKCEKC 302 K + L ++ + ++ E G++ + ++ L VH + + P +C +C K Sbjct: 367 CSKAFSNFSALRKHEIIHTGEKPYKCEECGKAFKWSSKLTVHKVIHMEEKPCKCEECGKA 426 Query: 303 FESEQILNEHSCFAARSGKIPSRF----KRSYNYKTIVK-KILAKLKRARSKKLDNFQSE 357 F+ L +H +GK P + K N T++K KI+ KK + Sbjct: 427 FKHFSALRKHKII--HTGKKPYKCEECGKAFNNSSTLMKHKII-----HTGKKPYKCEEC 479 Query: 358 KKVFKKS--FLRNCDLISGEQ--SSEQTQRTF--VGSLGKHGTYKTIGNRKKKTLTLPFS 411 K FK+S R+ + +GE+ E+ + F +L KH + I KK P+ Sbjct: 480 GKAFKQSSHLTRHKAIHTGEKPYKCEECGKAFNHFSALRKH---QIIHTGKK-----PYK 531 Query: 412 WQNMGKNLKGILTTENILSIDNSVNKKDLSICGSSGEEFFNNCEVLQCGFSVPRENIRTR 471 + GK S +++ K ++ +GE+ + CE +CG + + TR Sbjct: 532 CEECGK----------AFSQSSTLRKHEII---HTGEKPY-KCE--ECGKAFKWSSHLTR 575 Query: 472 HKIC-------PCDKCEKVFPSISKLKRHYLIHTGQRPFGCNICGKSFRQSAHLKRHEQT 524 HK+ C++C K F S L++H +IHTG++P+ C CGK+F QS+ L++HE Sbjct: 576 HKVIHTEEKPYKCEECGKAFNHFSALRKHKIIHTGKKPYKCEECGKAFSQSSTLRKHEII 635 Query: 525 HNEKSPYASLCQVEFGNFNNLSNHSGNNVNYNASQQCQA----------PGVQKYEVSES 574 H + PY C+ F S + + V + A + C+ ++K+++ + Sbjct: 636 HTGEKPYK--CEECGKAFKWSSKLTVHKVIHTAEKPCKCEECGKAFKHFSALRKHKIIHT 693 Query: 575 DQMSGVKAESQDFIPGSTGQPCLPNVLLESEQSNPF--CSYSEHQ-EKNDVFLYRCSVCA 631 + K E ++ ++ E+S C+ +H+ Y+C C Sbjct: 694 GK-KPYKCEECGKAFNNSSTLRKHEIIHTGEKSYKCEECALRKHEIIHTGKKPYKCEECG 752 Query: 632 KSFRSPSKLERHYLIHAGQKPFECSVCGKTFRQAPHWKRHQLTHFKERP 680 K+F + S L +H +I+ G+KP++C CGK F+Q+ H RH+ H E+P Sbjct: 753 KAFNNSSTLRKHKIIYTGKKPYKCEECGKAFKQSSHLTRHKAVHTGEKP 801 Score = 191 bits (484), Expect = 3e-48 Identities = 156/596 (26%), Positives = 250/596 (41%), Gaps = 117/596 (19%) Query: 112 KQVRRLLEAKQEKSMYGVYNTFTTEERWALHPCSKSDPMY----SMKRRKNIHA------ 161 K + E K + Y N T + + C+K ++ + R K IH Sbjct: 136 KDCESVNEGKMHEEAYNKLNQCWTTTQGKIFQCNKYVKVFHKYSNSNRYKIIHTGKKPYK 195 Query: 162 CTICGKMFPSQSKLDRHVLIHTGQRPFKCVLCTKSFRQSTHLKIHQLTHSEERPFQCCFC 221 C CGK F S L RH IHTG++P+KC C K+F + L+ HQ+ H+ ++P++C C Sbjct: 196 CEECGKAFKQSSHLTRHKAIHTGEKPYKCEECGKAFNHFSALRKHQIIHTGKKPYKCEEC 255 Query: 222 QKGFKIQSKLLKHKQIHTRNKAFRALLLKKRRTESRPLPNK--LNANQGGFENGEIGESE 279 K F S L KH+ IHT K ++ K + L ++ Q ++ E G++ Sbjct: 256 GKAFSQSSTLRKHEIIHTEEKPYKYEECGKAFSNLSALRKHEIIHTGQKPYKCEECGKAF 315 Query: 280 E-NNPLDVHSIYIV---PFQCPKCEKCFESEQILNEHSCFAARSGKIPSRFKRSYNYKTI 335 + ++ L VH + P +C +C K F+ L +H +GK P + + Sbjct: 316 KWSSKLTVHKVIHTAEKPCKCEECGKAFKRFSALRKHKII--HTGKQPYKCEEC------ 367 Query: 336 VKKILAKLKRARSKKLDNFQSEKKVFKKSFLRNCDLI-SGEQSSEQTQRTFVGSLGKHGT 394 SK NF S LR ++I +GE+ Sbjct: 368 ------------SKAFSNF---------SALRKHEIIHTGEK------------------ 388 Query: 395 YKTIGNRKKKTLTLPFSWQNMGKNLK--GILTTENILSIDNSVNKKDLSICGSSGEEFFN 452 P+ + GK K LT ++ ++ K C G+ F + Sbjct: 389 --------------PYKCEECGKAFKWSSKLTVHKVIHMEEKPCK-----CEECGKAFKH 429 Query: 453 NCEVLQCGFSVPREN--IRTRHKICPCDKCEKVFPSISKLKRHYLIHTGQRPFGCNICGK 510 FS R++ I T K C++C K F + S L +H +IHTG++P+ C CGK Sbjct: 430 --------FSALRKHKIIHTGKKPYKCEECGKAFNNSSTLMKHKIIHTGKKPYKCEECGK 481 Query: 511 SFRQSAHLKRHEQTHNEKSPY-ASLCQVEFGNFNNLSNHSGNNVNYNASQQCQAPGVQKY 569 +F+QS+HL RH+ H + PY C F +F+ L H Q G + Y Sbjct: 482 AFKQSSHLTRHKAIHTGEKPYKCEECGKAFNHFSALRKH-----------QIIHTGKKPY 530 Query: 570 EVSESDQMSGVKAESQDFIPGSTGQPCLPNVLLESEQSNPFCSYSEHQEKNDVFL----- 624 + E + + + TG+ + E+ +S H ++ V Sbjct: 531 KCEECGKAFSQSSTLRKHEIIHTGEKPY-----KCEECGKAFKWSSHLTRHKVIHTEEKP 585 Query: 625 YRCSVCAKSFRSPSKLERHYLIHAGQKPFECSVCGKTFRQAPHWKRHQLTHFKERP 680 Y+C C K+F S L +H +IH G+KP++C CGK F Q+ ++H++ H E+P Sbjct: 586 YKCEECGKAFNHFSALRKHKIIHTGKKPYKCEECGKAFSQSSTLRKHEIIHTGEKP 641 Score = 125 bits (314), Expect = 1e-28 Identities = 85/286 (29%), Positives = 129/286 (45%), Gaps = 50/286 (17%) Query: 3 AENNLKMLKIQQCVVANKLPRNRPYVCNICFKHFETPSKLARHYLIHTGQKPFECDVCHK 62 A NN L+ + + K +PY C C K F+ S L RH +HTG+KP++C C K Sbjct: 754 AFNNSSTLRKHKIIYTGK----KPYKCEECGKAFKQSSHLTRHKAVHTGEKPYKCGECGK 809 Query: 63 TFRQLVHLERHQLTHSLP--FKCSICQRHFKNLKTFVKHQQLHN-------------ETY 107 F L++H+L H+ +KC C + F N KH+ +H + + Sbjct: 810 AFNNSSTLKKHKLIHTREKSYKCEECGKAFSNFSALRKHKIIHTGEKPYKCEECECGKAF 869 Query: 108 QNNVKQVRRLLEAKQEKSMYGV-----YNTFTT----------EERWALHPCSKSDPMYS 152 N+ ++ + EK +N F+T E+ + C K+ S Sbjct: 870 NNSSTLMKHKIIHTGEKPYKCEECGKGFNNFSTLMKHKIIHTGEKPYKCEECGKAFKQSS 929 Query: 153 -MKRRKNIHA------CTICGKMFPSQSKLDRHVLIHTGQRPFKCVLCTK---------S 196 + + K+IH C GK F S+L +H +IHTG++P+KC C K + Sbjct: 930 HLTKHKSIHTGEKPYKCEERGKAFSHFSRLTKHRIIHTGKKPYKCEECEKPYKCEECGKA 989 Query: 197 FRQSTHLKIHQLTHSEERPFQCCFCQKGFKIQSKLLKHKQIHTRNK 242 F QS+HL H+ H+ + ++C C K F S L KHK IHT K Sbjct: 990 FNQSSHLTQHKTIHTGGKTYKCEECGKAFNHLSALTKHKIIHTGEK 1035 Score = 105 bits (262), Expect = 1e-22 Identities = 67/234 (28%), Positives = 106/234 (45%), Gaps = 28/234 (11%) Query: 3 AENNLKMLKIQQCVVANKLPRNRPYVCNICFKHFETPSKLARHYLIHTGQKPFECDVCH- 61 A NN LK + + R + Y C C K F S L +H +IHTG+KP++C+ C Sbjct: 810 AFNNSSTLKKHKLIHT----REKSYKCEECGKAFSNFSALRKHKIIHTGEKPYKCEECEC 865 Query: 62 -KTFRQLVHLERHQLTHS--LPFKCSICQRHFKNLKTFVKHQQLHNETYQNNVKQVRRLL 118 K F L +H++ H+ P+KC C + F N T +KH+ +H ++ + Sbjct: 866 GKAFNNSSTLMKHKIIHTGEKPYKCEECGKGFNNFSTLMKHKIIHTGEKPYKCEECGKAF 925 Query: 119 EAK----QEKSMYGVYNTFTTEERWA-------------LHPCSKSDPMYSMKRRKNIHA 161 + + KS++ + EER +H K Y + + + Sbjct: 926 KQSSHLTKHKSIHTGEKPYKCEERGKAFSHFSRLTKHRIIHTGKKP---YKCEECEKPYK 982 Query: 162 CTICGKMFPSQSKLDRHVLIHTGQRPFKCVLCTKSFRQSTHLKIHQLTHSEERP 215 C CGK F S L +H IHTG + +KC C K+F + L H++ H+ E+P Sbjct: 983 CEECGKAFNQSSHLTQHKTIHTGGKTYKCEECGKAFNHLSALTKHKIIHTGEKP 1036 >gi|239757212 PREDICTED: similar to hCG1773661 [Homo sapiens] Length = 1119 Score = 251 bits (640), Expect = 2e-66 Identities = 190/687 (27%), Positives = 310/687 (45%), Gaps = 100/687 (14%) Query: 25 RPYVCNICFKHFETPSKLARHYLIHTGQKPFECDVCHKTFRQLVHLERHQLTHS--LPFK 82 +PY C C K F S L RH IHTG+KP++C+ C K F L RH++ H+ P+K Sbjct: 325 KPYKCEECGKAFRQSSHLTRHKAIHTGEKPYKCEECGKAFNHFSDLRRHKIIHTGKKPYK 384 Query: 83 CSICQRHFKNLKTFVKHQQLHNETYQNNVKQVRRLLEAKQEKSMYGVYNTFTTEERWALH 142 C C + F T HQ +H ++ + + + +++ V +T E+ Sbjct: 385 CEECGKAFSQSSTLRNHQIIHTGEKPYKCEECGKAFKWSSKLTVHKVIHT--GEKPCKCE 442 Query: 143 PCSKSDPMYSMKR-------RKNIHACTICGKMFPSQSKLDRHVLIHTGQRPFKCVLCTK 195 C K+ +S R R+ ++ C CGK F + S L +H +IHTG++P+KC C K Sbjct: 443 ECGKAFKHFSALRKHKVIHTREKLYKCEECGKAFNNSSILAKHKIIHTGKKPYKCEECGK 502 Query: 196 SFRQSTHLKIHQLTHSEERPFQCCFCQKGFKIQSKLLKHKQIHTRNKAFRALLLKKRRTE 255 +FRQS+HL H+ H+ E+P++C C K F S L +HK IHT K ++ K + Sbjct: 503 AFRQSSHLTRHKAIHTGEKPYKCEECGKAFSHFSALRRHKIIHTGKKPYKCEECGKAFSH 562 Query: 256 SRPLPNK--LNANQGGFENGEIGESEE-NNPLDVHSIYIV---PFQCPKCEKCFESEQIL 309 L ++ + ++ E G++ + ++ L VH + P +C +C K F+ L Sbjct: 563 FSALRRHKIIHTGEKPYKCEECGKAFKWSSKLTVHKVIHTAEKPCKCEECGKSFKHFSAL 622 Query: 310 NEHSCFAARSG--KIPSRFKRSYNYKTIVKKILAKLKRARSKKLDNFQSEKKVFKKSFLR 367 +H R K K ++ ++K + +K + K FK S Sbjct: 623 RKHKVIHTREKLYKCEECVKAFNSFSALMKHKVIHT----GEKPYKCEECGKAFKWSSKL 678 Query: 368 NCDLI--SGEQ--SSEQTQRTF--VGSLGKHGTYKTIGNRKKKTLTLPFSWQNMGKNLKG 421 + +GE+ E+ + F +L KH K I KK P+ + GK Sbjct: 679 TVHKVIHTGEKPCKCEECGKAFKHFSALRKH---KVIHTGKK-----PYKCEECGK---- 726 Query: 422 ILTTENILSIDNSVNKKDLSICGSSGEEFFNNCEVLQCGFSVPRENIRTRHKI------- 474 S +S+ K ++ SGE+ + CE +CG + + T HK+ Sbjct: 727 ------AFSQSSSLRKHEII---HSGEKPYK-CE--ECGKAFKWLSKLTVHKVIHTAEKP 774 Query: 475 CPCDKCEKVFPSISKLKRHYLIHTGQRPFGCNICGKSFRQSAHLKRHEQTHNEKSPY-AS 533 C C++C K F S L++H +IHTG++P+ C CGK+F S+ L +H+ H K PY + Sbjct: 775 CKCEECGKAFKHFSALRKHKIIHTGKKPYKCEECGKAFNDSSTLMKHKIIHTGKKPYKCA 834 Query: 534 LCQVEFGNFNNLSNHSGNNVNYNASQQCQAPGVQKYEVSESDQMSGVKAESQDFIPGSTG 593 C F ++L+ H + G + Y+ E +DF ST Sbjct: 835 ECGKAFKQSSHLTRHKAIHT-----------GEKPYKCEEC---------GKDFNNSST- 873 Query: 594 QPCLPNVLLESEQSNPFCSYSEHQEKNDVFLYRCSVCAKSFRSPSKLERHYLIHAGQKPF 653 + L+ + + LY+C C K+F + S L +H +IH G+KP+ Sbjct: 874 --LKKHKLIHTREK----------------LYKCEECVKAFNNFSALMKHKIIHTGEKPY 915 Query: 654 ECSVCGKTFRQAPHWKRHQLTHFKERP 680 +C CGK F+ + H++ H E+P Sbjct: 916 KCEECGKAFKWSSKLTEHKVIHTGEKP 942 Score = 249 bits (635), Expect = 8e-66 Identities = 196/711 (27%), Positives = 307/711 (43%), Gaps = 92/711 (12%) Query: 25 RPYVCNICFKHFETPSKLARHYLIHTGQKPFECDVCHKTFRQLVHLERHQLTHSLP--FK 82 +PY C C K F+ SKL H +IHTG+KP +C+ C K F+ L +H++ H+ +K Sbjct: 409 KPYKCEECGKAFKWSSKLTVHKVIHTGEKPCKCEECGKAFKHFSALRKHKVIHTREKLYK 468 Query: 83 CSICQRHFKNLKTFVKHQQLHNETYQNNVKQVRRLLEAKQEKSMYGVYNTFTTEERWALH 142 C C + F N KH+ +H ++ + + + +T E+ + Sbjct: 469 CEECGKAFNNSSILAKHKIIHTGKKPYKCEECGKAFRQSSHLTRHKAIHT--GEKPYKCE 526 Query: 143 PCSKSDPMYS-MKRRKNIHA------CTICGKMFPSQSKLDRHVLIHTGQRPFKCVLCTK 195 C K+ +S ++R K IH C CGK F S L RH +IHTG++P+KC C K Sbjct: 527 ECGKAFSHFSALRRHKIIHTGKKPYKCEECGKAFSHFSALRRHKIIHTGEKPYKCEECGK 586 Query: 196 SFRQSTHLKIHQLTHSEERPFQCCFCQKGFKIQSKLLKHKQIHTRNKAFRAL-LLKKRRT 254 +F+ S+ L +H++ H+ E+P +C C K FK S L KHK IHTR K ++ +K + Sbjct: 587 AFKWSSKLTVHKVIHTAEKPCKCEECGKSFKHFSALRKHKVIHTREKLYKCEECVKAFNS 646 Query: 255 ESRPLPNK-LNANQGGFENGEIGESEE-NNPLDVHSIYIV-------------------- 292 S + +K ++ + ++ E G++ + ++ L VH + Sbjct: 647 FSALMKHKVIHTGEKPYKCEECGKAFKWSSKLTVHKVIHTGEKPCKCEECGKAFKHFSAL 706 Query: 293 -----------PFQCPKCEKCFESEQILNEHSCFAARSGKIPSRFKRSYN-YKTIVKKIL 340 P++C +C K F L +H SG+ P + + +K + K + Sbjct: 707 RKHKVIHTGKKPYKCEECGKAFSQSSSLRKHEII--HSGEKPYKCEECGKAFKWLSKLTV 764 Query: 341 AKLKRARSKKLDNFQSEKKVFKKSFLRNCDLI-SGEQ--SSEQTQRTFVGS--LGKHGTY 395 K+ K + K S LR +I +G++ E+ + F S L KH Sbjct: 765 HKVIHTAEKPCKCEECGKAFKHFSALRKHKIIHTGKKPYKCEECGKAFNDSSTLMKH--- 821 Query: 396 KTIGNRKKKTLTLPFSWQNMGKNLKGILTTENILSIDNSVNKKDLSICGSSGEEFFNNCE 455 K I KK P+ GK K +I CG FNN Sbjct: 822 KIIHTGKK-----PYKCAECGKAFKQSSHLTRHKAIHTGEKPYKCEECGKD----FNNSS 872 Query: 456 VLQCGFSVPRENIRTRHKICPCDKCEKVFPSISKLKRHYLIHTGQRPFGCNICGKSFRQS 515 L+ + I TR K+ C++C K F + S L +H +IHTG++P+ C CGK+F+ S Sbjct: 873 TLK-----KHKLIHTREKLYKCEECVKAFNNFSALMKHKIIHTGEKPYKCEECGKAFKWS 927 Query: 516 AHLKRHEQTH-NEKSPYASLCQVEFGNFNNLSNHSGNNVNYNASQQCQAPGVQKYEVSES 574 + L H+ H EK C F +F+ L H + QC E ++ Sbjct: 928 SKLTEHKVIHTGEKPCKCEECDKAFKHFSALRKHKVIHTG-KKPYQCD-------ECGKA 979 Query: 575 DQMSGVKAESQDFIPGSTGQPCLPNVLLESEQSNPFCSYSEHQEKNDVF-----LYRCSV 629 S + + G C E+ S S K+ + Y+C Sbjct: 980 FNNSSTLTKHKIIHTGEKPYKC--------EECGKAFSQSSILTKHKIIHSVEKPYKCEE 1031 Query: 630 CAKSFRSPSKLERHYLIHAGQKPFECSVCGKTFRQAPHWKRHQLTHFKERP 680 C K+F S L RH IH G+KP++C CGK F Q + RH+ H +E+P Sbjct: 1032 CGKAFNQSSHLTRHKTIHTGEKPYKCEECGKAFIQCSYLIRHKTIHTREKP 1082 Score = 217 bits (553), Expect = 3e-56 Identities = 194/732 (26%), Positives = 315/732 (43%), Gaps = 111/732 (15%) Query: 11 KIQQCVVANKLPRNRPYVCNICFKHFETPSKLARHYLIHTGQKPFECDVCHKTFRQLVHL 70 K+ QC A + + + CN K F S R+ + HT +K F+C C K+F L L Sbjct: 8 KLNQCRTATQ---RKIFQCNKHMKVFHKYSN--RNKVRHTKKKTFKCIKCSKSFFMLSCL 62 Query: 71 ERHQLTHSLP--FKCSICQRHFKNLKTFVKHQQLHNETYQNNVKQVRRLLEAKQEKSMYG 128 RH+ H +KC + FK+ T KH+ +H E K+ + Sbjct: 63 IRHKRIHIRQNIYKCEERGKAFKSFSTLTKHKIIHTEDKPYKYKKCGNAFKFS------- 115 Query: 129 VYNTFTTEERWALHPCSKSDPMYSMKRRKNIHACTICGKMFPSQSKLDRHVLIHTGQRPF 188 +TFT +R + + C CGK F S L H IHTG++ + Sbjct: 116 --STFTKHKR--------------IHTGETPFRCEECGKAFNQSSNLTDHKRIHTGEKTY 159 Query: 189 KCVLCTKSFRQSTHLKIHQLTHSEERPFQCCFCQKGFKIQSKLLKHKQIHTRNKAFRALL 248 KC C K+F+ S++ H++ H+ E+P++C C K F S L KHK IHT K ++ Sbjct: 160 KCEECGKAFKGSSNFNAHKVIHTAEKPYKCEDCGKTFNHFSALRKHKIIHTGKKPYKREE 219 Query: 249 LKKRRTESRPLPNK--LNANQGGFENGEIGES-EENNPLDVHSIYIV---PFQCPKCEKC 302 K ++S L ++ + ++ E G++ + ++ L VH + P++C +C K Sbjct: 220 CGKAFSQSSTLRKHEIIHTGEKPYKCEECGKAFKWSSKLTVHKVVHTGEKPYKCEECGKA 279 Query: 303 FESEQILNEHSCFAARSGKIPSRFK---RSYNYKTIVKKILAKLKRARSKKLDNFQSEKK 359 F L +H +GK P + + +++N + + K K+ K + K Sbjct: 280 FSQFSTLKKHKII--HTGKKPYKCEECGKAFNSSSTLMK--HKIIHTGEKPYKCEECGKA 335 Query: 360 VFKKSFL-RNCDLISGEQ--SSEQTQRTF--VGSLGKHGTYKTIGNRKKKTLTLPFSWQN 414 + S L R+ + +GE+ E+ + F L +H K I KK P+ + Sbjct: 336 FRQSSHLTRHKAIHTGEKPYKCEECGKAFNHFSDLRRH---KIIHTGKK-----PYKCEE 387 Query: 415 MGKNLKGILTTENILSIDNSVNKKDLSICGS---------------SGEEFFNNCEVLQC 459 GK T N I CG +GE+ C+ +C Sbjct: 388 CGKAFSQSSTLRNHQIIHTGEKPYKCEECGKAFKWSSKLTVHKVIHTGEK---PCKCEEC 444 Query: 460 G-----FSVPREN--IRTRHKICPCDKCEKVFPSISKLKRHYLIHTGQRPFGCNICGKSF 512 G FS R++ I TR K+ C++C K F + S L +H +IHTG++P+ C CGK+F Sbjct: 445 GKAFKHFSALRKHKVIHTREKLYKCEECGKAFNNSSILAKHKIIHTGKKPYKCEECGKAF 504 Query: 513 RQSAHLKRHEQTHNEKSPY-ASLCQVEFGNFNNLSNHS---GNNVNYNASQQCQA----- 563 RQS+HL RH+ H + PY C F +F+ L H Y + +A Sbjct: 505 RQSSHLTRHKAIHTGEKPYKCEECGKAFSHFSALRRHKIIHTGKKPYKCEECGKAFSHFS 564 Query: 564 ---------PGVQKYEVSESDQMSGVKAE-SQDFIPGSTGQPCLPNVLLESEQSNPFCSY 613 G + Y+ E + ++ + + + +PC + E+ + Sbjct: 565 ALRRHKIIHTGEKPYKCEECGKAFKWSSKLTVHKVIHTAEKPC------KCEECGKSFKH 618 Query: 614 SEHQEKNDVF-----LYRCSVCAKSFRSPSKLERHYLIHAGQKPFECSVCGKTFRQAPHW 668 K+ V LY+C C K+F S S L +H +IH G+KP++C CGK F+ + Sbjct: 619 FSALRKHKVIHTREKLYKCEECVKAFNSFSALMKHKVIHTGEKPYKCEECGKAFKWSSKL 678 Query: 669 KRHQLTHFKERP 680 H++ H E+P Sbjct: 679 TVHKVIHTGEKP 690 Score = 177 bits (448), Expect = 4e-44 Identities = 147/536 (27%), Positives = 242/536 (45%), Gaps = 80/536 (14%) Query: 8 KMLKIQQCVVA----NKLPRNR-------PYVCNICFKHFETPSKLARHYLIHTGQKPFE 56 K+ K ++CV A + L +++ PY C C K F+ SKL H +IHTG+KP + Sbjct: 633 KLYKCEECVKAFNSFSALMKHKVIHTGEKPYKCEECGKAFKWSSKLTVHKVIHTGEKPCK 692 Query: 57 CDVCHKTFRQLVHLERHQLTHS--LPFKCSICQRHFKNLKTFVKHQQLHNETYQNNVKQV 114 C+ C K F+ L +H++ H+ P+KC C + F + KH+ +H+ ++ Sbjct: 693 CEECGKAFKHFSALRKHKVIHTGKKPYKCEECGKAFSQSSSLRKHEIIHSGEKPYKCEEC 752 Query: 115 RRLLEAKQEKSMYGVYNTFTTEERWALHPCSKSDPMYS-MKRRKNIHA------CTICGK 167 + + + +++ V +T E+ C K+ +S +++ K IH C CGK Sbjct: 753 GKAFKWLSKLTVHKVIHT--AEKPCKCEECGKAFKHFSALRKHKIIHTGKKPYKCEECGK 810 Query: 168 MFPSQSKLDRHVLIHTGQRPFKCVLCTKSFRQSTHLKIHQLTHSEERPFQCCFCQKGFKI 227 F S L +H +IHTG++P+KC C K+F+QS+HL H+ H+ E+P++C C K F Sbjct: 811 AFNDSSTLMKHKIIHTGKKPYKCAECGKAFKQSSHLTRHKAIHTGEKPYKCEECGKDFNN 870 Query: 228 QSKLLKHKQIHTRNKAFRAL-LLKKRRTESRPLPNKLNANQGGFENGEIGESEENNPLDV 286 S L KHK IHTR K ++ +K S + +K+ GE Sbjct: 871 SSTLKKHKLIHTREKLYKCEECVKAFNNFSALMKHKI------IHTGE------------ 912 Query: 287 HSIYIVPFQCPKCEKCFESEQILNEHSCFAARSGKIPSRFK---RSYNYKTIVKKILAKL 343 P++C +C K F+ L EH +G+ P + + +++ + + ++K K+ Sbjct: 913 -----KPYKCEECGKAFKWSSKLTEHKVI--HTGEKPCKCEECDKAFKHFSALRK--HKV 963 Query: 344 KRARSKKLDNFQSEKKVFKKSFLRNCDLI-SGEQ--SSEQTQRTFVGS--LGKHGTYKTI 398 K + K S L +I +GE+ E+ + F S L KH K I Sbjct: 964 IHTGKKPYQCDECGKAFNNSSTLTKHKIIHTGEKPYKCEECGKAFSQSSILTKH---KII 1020 Query: 399 GNRKKKTLTLPFSWQNMGK--NLKGILTTENILSIDNSVNKKDLSICGSSGEEFFNNCEV 456 + +K P+ + GK N LT + K C G+ F Sbjct: 1021 HSVEK-----PYKCEECGKAFNQSSHLTRHKTIHTGEKPYK-----CEECGKAF------ 1064 Query: 457 LQCGFSVPRENIRTRHKICPCDKCEKVFPSISKLKRHYLIHTGQRPFGCNICGKSF 512 +QC + + + I TR K K K+ + L IHTG++P+ C C K+F Sbjct: 1065 IQCSYLIRHKTIHTREKPTNVKKVPKLLSNPHTLLDK-TIHTGEKPYKCEECAKAF 1119 >gi|239751718 PREDICTED: similar to hCG1773661 [Homo sapiens] Length = 1119 Score = 251 bits (640), Expect = 2e-66 Identities = 190/687 (27%), Positives = 310/687 (45%), Gaps = 100/687 (14%) Query: 25 RPYVCNICFKHFETPSKLARHYLIHTGQKPFECDVCHKTFRQLVHLERHQLTHS--LPFK 82 +PY C C K F S L RH IHTG+KP++C+ C K F L RH++ H+ P+K Sbjct: 325 KPYKCEECGKAFRQSSHLTRHKAIHTGEKPYKCEECGKAFNHFSDLRRHKIIHTGKKPYK 384 Query: 83 CSICQRHFKNLKTFVKHQQLHNETYQNNVKQVRRLLEAKQEKSMYGVYNTFTTEERWALH 142 C C + F T HQ +H ++ + + + +++ V +T E+ Sbjct: 385 CEECGKAFSQSSTLRNHQIIHTGEKPYKCEECGKAFKWSSKLTVHKVIHT--GEKPCKCE 442 Query: 143 PCSKSDPMYSMKR-------RKNIHACTICGKMFPSQSKLDRHVLIHTGQRPFKCVLCTK 195 C K+ +S R R+ ++ C CGK F + S L +H +IHTG++P+KC C K Sbjct: 443 ECGKAFKHFSALRKHKVIHTREKLYKCEECGKAFNNSSILAKHKIIHTGKKPYKCEECGK 502 Query: 196 SFRQSTHLKIHQLTHSEERPFQCCFCQKGFKIQSKLLKHKQIHTRNKAFRALLLKKRRTE 255 +FRQS+HL H+ H+ E+P++C C K F S L +HK IHT K ++ K + Sbjct: 503 AFRQSSHLTRHKAIHTGEKPYKCEECGKAFSHFSALRRHKIIHTGKKPYKCEECGKAFSH 562 Query: 256 SRPLPNK--LNANQGGFENGEIGESEE-NNPLDVHSIYIV---PFQCPKCEKCFESEQIL 309 L ++ + ++ E G++ + ++ L VH + P +C +C K F+ L Sbjct: 563 FSALRRHKIIHTGEKPYKCEECGKAFKWSSKLTVHKVIHTAEKPCKCEECGKSFKHFSAL 622 Query: 310 NEHSCFAARSG--KIPSRFKRSYNYKTIVKKILAKLKRARSKKLDNFQSEKKVFKKSFLR 367 +H R K K ++ ++K + +K + K FK S Sbjct: 623 RKHKVIHTREKLYKCEECVKAFNSFSALMKHKVIHT----GEKPYKCEECGKAFKWSSKL 678 Query: 368 NCDLI--SGEQ--SSEQTQRTF--VGSLGKHGTYKTIGNRKKKTLTLPFSWQNMGKNLKG 421 + +GE+ E+ + F +L KH K I KK P+ + GK Sbjct: 679 TVHKVIHTGEKPCKCEECGKAFKHFSALRKH---KVIHTGKK-----PYKCEECGK---- 726 Query: 422 ILTTENILSIDNSVNKKDLSICGSSGEEFFNNCEVLQCGFSVPRENIRTRHKI------- 474 S +S+ K ++ SGE+ + CE +CG + + T HK+ Sbjct: 727 ------AFSQSSSLRKHEII---HSGEKPYK-CE--ECGKAFKWLSKLTVHKVIHTAEKP 774 Query: 475 CPCDKCEKVFPSISKLKRHYLIHTGQRPFGCNICGKSFRQSAHLKRHEQTHNEKSPY-AS 533 C C++C K F S L++H +IHTG++P+ C CGK+F S+ L +H+ H K PY + Sbjct: 775 CKCEECGKAFKHFSALRKHKIIHTGKKPYKCEECGKAFNDSSTLMKHKIIHTGKKPYKCA 834 Query: 534 LCQVEFGNFNNLSNHSGNNVNYNASQQCQAPGVQKYEVSESDQMSGVKAESQDFIPGSTG 593 C F ++L+ H + G + Y+ E +DF ST Sbjct: 835 ECGKAFKQSSHLTRHKAIHT-----------GEKPYKCEEC---------GKDFNNSST- 873 Query: 594 QPCLPNVLLESEQSNPFCSYSEHQEKNDVFLYRCSVCAKSFRSPSKLERHYLIHAGQKPF 653 + L+ + + LY+C C K+F + S L +H +IH G+KP+ Sbjct: 874 --LKKHKLIHTREK----------------LYKCEECVKAFNNFSALMKHKIIHTGEKPY 915 Query: 654 ECSVCGKTFRQAPHWKRHQLTHFKERP 680 +C CGK F+ + H++ H E+P Sbjct: 916 KCEECGKAFKWSSKLTEHKVIHTGEKP 942 Score = 249 bits (635), Expect = 8e-66 Identities = 196/711 (27%), Positives = 307/711 (43%), Gaps = 92/711 (12%) Query: 25 RPYVCNICFKHFETPSKLARHYLIHTGQKPFECDVCHKTFRQLVHLERHQLTHSLP--FK 82 +PY C C K F+ SKL H +IHTG+KP +C+ C K F+ L +H++ H+ +K Sbjct: 409 KPYKCEECGKAFKWSSKLTVHKVIHTGEKPCKCEECGKAFKHFSALRKHKVIHTREKLYK 468 Query: 83 CSICQRHFKNLKTFVKHQQLHNETYQNNVKQVRRLLEAKQEKSMYGVYNTFTTEERWALH 142 C C + F N KH+ +H ++ + + + +T E+ + Sbjct: 469 CEECGKAFNNSSILAKHKIIHTGKKPYKCEECGKAFRQSSHLTRHKAIHT--GEKPYKCE 526 Query: 143 PCSKSDPMYS-MKRRKNIHA------CTICGKMFPSQSKLDRHVLIHTGQRPFKCVLCTK 195 C K+ +S ++R K IH C CGK F S L RH +IHTG++P+KC C K Sbjct: 527 ECGKAFSHFSALRRHKIIHTGKKPYKCEECGKAFSHFSALRRHKIIHTGEKPYKCEECGK 586 Query: 196 SFRQSTHLKIHQLTHSEERPFQCCFCQKGFKIQSKLLKHKQIHTRNKAFRAL-LLKKRRT 254 +F+ S+ L +H++ H+ E+P +C C K FK S L KHK IHTR K ++ +K + Sbjct: 587 AFKWSSKLTVHKVIHTAEKPCKCEECGKSFKHFSALRKHKVIHTREKLYKCEECVKAFNS 646 Query: 255 ESRPLPNK-LNANQGGFENGEIGESEE-NNPLDVHSIYIV-------------------- 292 S + +K ++ + ++ E G++ + ++ L VH + Sbjct: 647 FSALMKHKVIHTGEKPYKCEECGKAFKWSSKLTVHKVIHTGEKPCKCEECGKAFKHFSAL 706 Query: 293 -----------PFQCPKCEKCFESEQILNEHSCFAARSGKIPSRFKRSYN-YKTIVKKIL 340 P++C +C K F L +H SG+ P + + +K + K + Sbjct: 707 RKHKVIHTGKKPYKCEECGKAFSQSSSLRKHEII--HSGEKPYKCEECGKAFKWLSKLTV 764 Query: 341 AKLKRARSKKLDNFQSEKKVFKKSFLRNCDLI-SGEQ--SSEQTQRTFVGS--LGKHGTY 395 K+ K + K S LR +I +G++ E+ + F S L KH Sbjct: 765 HKVIHTAEKPCKCEECGKAFKHFSALRKHKIIHTGKKPYKCEECGKAFNDSSTLMKH--- 821 Query: 396 KTIGNRKKKTLTLPFSWQNMGKNLKGILTTENILSIDNSVNKKDLSICGSSGEEFFNNCE 455 K I KK P+ GK K +I CG FNN Sbjct: 822 KIIHTGKK-----PYKCAECGKAFKQSSHLTRHKAIHTGEKPYKCEECGKD----FNNSS 872 Query: 456 VLQCGFSVPRENIRTRHKICPCDKCEKVFPSISKLKRHYLIHTGQRPFGCNICGKSFRQS 515 L+ + I TR K+ C++C K F + S L +H +IHTG++P+ C CGK+F+ S Sbjct: 873 TLK-----KHKLIHTREKLYKCEECVKAFNNFSALMKHKIIHTGEKPYKCEECGKAFKWS 927 Query: 516 AHLKRHEQTH-NEKSPYASLCQVEFGNFNNLSNHSGNNVNYNASQQCQAPGVQKYEVSES 574 + L H+ H EK C F +F+ L H + QC E ++ Sbjct: 928 SKLTEHKVIHTGEKPCKCEECDKAFKHFSALRKHKVIHTG-KKPYQCD-------ECGKA 979 Query: 575 DQMSGVKAESQDFIPGSTGQPCLPNVLLESEQSNPFCSYSEHQEKNDVF-----LYRCSV 629 S + + G C E+ S S K+ + Y+C Sbjct: 980 FNNSSTLTKHKIIHTGEKPYKC--------EECGKAFSQSSILTKHKIIHSVEKPYKCEE 1031 Query: 630 CAKSFRSPSKLERHYLIHAGQKPFECSVCGKTFRQAPHWKRHQLTHFKERP 680 C K+F S L RH IH G+KP++C CGK F Q + RH+ H +E+P Sbjct: 1032 CGKAFNQSSHLTRHKTIHTGEKPYKCEECGKAFIQCSYLIRHKTIHTREKP 1082 Score = 217 bits (553), Expect = 3e-56 Identities = 194/732 (26%), Positives = 315/732 (43%), Gaps = 111/732 (15%) Query: 11 KIQQCVVANKLPRNRPYVCNICFKHFETPSKLARHYLIHTGQKPFECDVCHKTFRQLVHL 70 K+ QC A + + + CN K F S R+ + HT +K F+C C K+F L L Sbjct: 8 KLNQCRTATQ---RKIFQCNKHMKVFHKYSN--RNKVRHTKKKTFKCIKCSKSFFMLSCL 62 Query: 71 ERHQLTHSLP--FKCSICQRHFKNLKTFVKHQQLHNETYQNNVKQVRRLLEAKQEKSMYG 128 RH+ H +KC + FK+ T KH+ +H E K+ + Sbjct: 63 IRHKRIHIRQNIYKCEERGKAFKSFSTLTKHKIIHTEDKPYKYKKCGNAFKFS------- 115 Query: 129 VYNTFTTEERWALHPCSKSDPMYSMKRRKNIHACTICGKMFPSQSKLDRHVLIHTGQRPF 188 +TFT +R + + C CGK F S L H IHTG++ + Sbjct: 116 --STFTKHKR--------------IHTGETPFRCEECGKAFNQSSNLTDHKRIHTGEKTY 159 Query: 189 KCVLCTKSFRQSTHLKIHQLTHSEERPFQCCFCQKGFKIQSKLLKHKQIHTRNKAFRALL 248 KC C K+F+ S++ H++ H+ E+P++C C K F S L KHK IHT K ++ Sbjct: 160 KCEECGKAFKGSSNFNAHKVIHTAEKPYKCEDCGKTFNHFSALRKHKIIHTGKKPYKREE 219 Query: 249 LKKRRTESRPLPNK--LNANQGGFENGEIGES-EENNPLDVHSIYIV---PFQCPKCEKC 302 K ++S L ++ + ++ E G++ + ++ L VH + P++C +C K Sbjct: 220 CGKAFSQSSTLRKHEIIHTGEKPYKCEECGKAFKWSSKLTVHKVVHTGEKPYKCEECGKA 279 Query: 303 FESEQILNEHSCFAARSGKIPSRFK---RSYNYKTIVKKILAKLKRARSKKLDNFQSEKK 359 F L +H +GK P + + +++N + + K K+ K + K Sbjct: 280 FSQFSTLKKHKII--HTGKKPYKCEECGKAFNSSSTLMK--HKIIHTGEKPYKCEECGKA 335 Query: 360 VFKKSFL-RNCDLISGEQ--SSEQTQRTF--VGSLGKHGTYKTIGNRKKKTLTLPFSWQN 414 + S L R+ + +GE+ E+ + F L +H K I KK P+ + Sbjct: 336 FRQSSHLTRHKAIHTGEKPYKCEECGKAFNHFSDLRRH---KIIHTGKK-----PYKCEE 387 Query: 415 MGKNLKGILTTENILSIDNSVNKKDLSICGS---------------SGEEFFNNCEVLQC 459 GK T N I CG +GE+ C+ +C Sbjct: 388 CGKAFSQSSTLRNHQIIHTGEKPYKCEECGKAFKWSSKLTVHKVIHTGEK---PCKCEEC 444 Query: 460 G-----FSVPREN--IRTRHKICPCDKCEKVFPSISKLKRHYLIHTGQRPFGCNICGKSF 512 G FS R++ I TR K+ C++C K F + S L +H +IHTG++P+ C CGK+F Sbjct: 445 GKAFKHFSALRKHKVIHTREKLYKCEECGKAFNNSSILAKHKIIHTGKKPYKCEECGKAF 504 Query: 513 RQSAHLKRHEQTHNEKSPY-ASLCQVEFGNFNNLSNHS---GNNVNYNASQQCQA----- 563 RQS+HL RH+ H + PY C F +F+ L H Y + +A Sbjct: 505 RQSSHLTRHKAIHTGEKPYKCEECGKAFSHFSALRRHKIIHTGKKPYKCEECGKAFSHFS 564 Query: 564 ---------PGVQKYEVSESDQMSGVKAE-SQDFIPGSTGQPCLPNVLLESEQSNPFCSY 613 G + Y+ E + ++ + + + +PC + E+ + Sbjct: 565 ALRRHKIIHTGEKPYKCEECGKAFKWSSKLTVHKVIHTAEKPC------KCEECGKSFKH 618 Query: 614 SEHQEKNDVF-----LYRCSVCAKSFRSPSKLERHYLIHAGQKPFECSVCGKTFRQAPHW 668 K+ V LY+C C K+F S S L +H +IH G+KP++C CGK F+ + Sbjct: 619 FSALRKHKVIHTREKLYKCEECVKAFNSFSALMKHKVIHTGEKPYKCEECGKAFKWSSKL 678 Query: 669 KRHQLTHFKERP 680 H++ H E+P Sbjct: 679 TVHKVIHTGEKP 690 Score = 177 bits (448), Expect = 4e-44 Identities = 147/536 (27%), Positives = 242/536 (45%), Gaps = 80/536 (14%) Query: 8 KMLKIQQCVVA----NKLPRNR-------PYVCNICFKHFETPSKLARHYLIHTGQKPFE 56 K+ K ++CV A + L +++ PY C C K F+ SKL H +IHTG+KP + Sbjct: 633 KLYKCEECVKAFNSFSALMKHKVIHTGEKPYKCEECGKAFKWSSKLTVHKVIHTGEKPCK 692 Query: 57 CDVCHKTFRQLVHLERHQLTHS--LPFKCSICQRHFKNLKTFVKHQQLHNETYQNNVKQV 114 C+ C K F+ L +H++ H+ P+KC C + F + KH+ +H+ ++ Sbjct: 693 CEECGKAFKHFSALRKHKVIHTGKKPYKCEECGKAFSQSSSLRKHEIIHSGEKPYKCEEC 752 Query: 115 RRLLEAKQEKSMYGVYNTFTTEERWALHPCSKSDPMYS-MKRRKNIHA------CTICGK 167 + + + +++ V +T E+ C K+ +S +++ K IH C CGK Sbjct: 753 GKAFKWLSKLTVHKVIHT--AEKPCKCEECGKAFKHFSALRKHKIIHTGKKPYKCEECGK 810 Query: 168 MFPSQSKLDRHVLIHTGQRPFKCVLCTKSFRQSTHLKIHQLTHSEERPFQCCFCQKGFKI 227 F S L +H +IHTG++P+KC C K+F+QS+HL H+ H+ E+P++C C K F Sbjct: 811 AFNDSSTLMKHKIIHTGKKPYKCAECGKAFKQSSHLTRHKAIHTGEKPYKCEECGKDFNN 870 Query: 228 QSKLLKHKQIHTRNKAFRAL-LLKKRRTESRPLPNKLNANQGGFENGEIGESEENNPLDV 286 S L KHK IHTR K ++ +K S + +K+ GE Sbjct: 871 SSTLKKHKLIHTREKLYKCEECVKAFNNFSALMKHKI------IHTGE------------ 912 Query: 287 HSIYIVPFQCPKCEKCFESEQILNEHSCFAARSGKIPSRFK---RSYNYKTIVKKILAKL 343 P++C +C K F+ L EH +G+ P + + +++ + + ++K K+ Sbjct: 913 -----KPYKCEECGKAFKWSSKLTEHKVI--HTGEKPCKCEECDKAFKHFSALRK--HKV 963 Query: 344 KRARSKKLDNFQSEKKVFKKSFLRNCDLI-SGEQ--SSEQTQRTFVGS--LGKHGTYKTI 398 K + K S L +I +GE+ E+ + F S L KH K I Sbjct: 964 IHTGKKPYQCDECGKAFNNSSTLTKHKIIHTGEKPYKCEECGKAFSQSSILTKH---KII 1020 Query: 399 GNRKKKTLTLPFSWQNMGK--NLKGILTTENILSIDNSVNKKDLSICGSSGEEFFNNCEV 456 + +K P+ + GK N LT + K C G+ F Sbjct: 1021 HSVEK-----PYKCEECGKAFNQSSHLTRHKTIHTGEKPYK-----CEECGKAF------ 1064 Query: 457 LQCGFSVPRENIRTRHKICPCDKCEKVFPSISKLKRHYLIHTGQRPFGCNICGKSF 512 +QC + + + I TR K K K+ + L IHTG++P+ C C K+F Sbjct: 1065 IQCSYLIRHKTIHTREKPTNVKKVPKLLSNPHTLLDK-TIHTGEKPYKCEECAKAF 1119 >gi|239746221 PREDICTED: hypothetical protein XP_002343677 [Homo sapiens] Length = 1119 Score = 251 bits (640), Expect = 2e-66 Identities = 190/687 (27%), Positives = 310/687 (45%), Gaps = 100/687 (14%) Query: 25 RPYVCNICFKHFETPSKLARHYLIHTGQKPFECDVCHKTFRQLVHLERHQLTHS--LPFK 82 +PY C C K F S L RH IHTG+KP++C+ C K F L RH++ H+ P+K Sbjct: 325 KPYKCEECGKAFRQSSHLTRHKAIHTGEKPYKCEECGKAFNHFSDLRRHKIIHTGKKPYK 384 Query: 83 CSICQRHFKNLKTFVKHQQLHNETYQNNVKQVRRLLEAKQEKSMYGVYNTFTTEERWALH 142 C C + F T HQ +H ++ + + + +++ V +T E+ Sbjct: 385 CEECGKAFSQSSTLRNHQIIHTGEKPYKCEECGKAFKWSSKLTVHKVIHT--GEKPCKCE 442 Query: 143 PCSKSDPMYSMKR-------RKNIHACTICGKMFPSQSKLDRHVLIHTGQRPFKCVLCTK 195 C K+ +S R R+ ++ C CGK F + S L +H +IHTG++P+KC C K Sbjct: 443 ECGKAFKHFSALRKHKVIHTREKLYKCEECGKAFNNSSILAKHKIIHTGKKPYKCEECGK 502 Query: 196 SFRQSTHLKIHQLTHSEERPFQCCFCQKGFKIQSKLLKHKQIHTRNKAFRALLLKKRRTE 255 +FRQS+HL H+ H+ E+P++C C K F S L +HK IHT K ++ K + Sbjct: 503 AFRQSSHLTRHKAIHTGEKPYKCEECGKAFSHFSALRRHKIIHTGKKPYKCEECGKAFSH 562 Query: 256 SRPLPNK--LNANQGGFENGEIGESEE-NNPLDVHSIYIV---PFQCPKCEKCFESEQIL 309 L ++ + ++ E G++ + ++ L VH + P +C +C K F+ L Sbjct: 563 FSALRRHKIIHTGEKPYKCEECGKAFKWSSKLTVHKVIHTAEKPCKCEECGKSFKHFSAL 622 Query: 310 NEHSCFAARSG--KIPSRFKRSYNYKTIVKKILAKLKRARSKKLDNFQSEKKVFKKSFLR 367 +H R K K ++ ++K + +K + K FK S Sbjct: 623 RKHKVIHTREKLYKCEECVKAFNSFSALMKHKVIHT----GEKPYKCEECGKAFKWSSKL 678 Query: 368 NCDLI--SGEQ--SSEQTQRTF--VGSLGKHGTYKTIGNRKKKTLTLPFSWQNMGKNLKG 421 + +GE+ E+ + F +L KH K I KK P+ + GK Sbjct: 679 TVHKVIHTGEKPCKCEECGKAFKHFSALRKH---KVIHTGKK-----PYKCEECGK---- 726 Query: 422 ILTTENILSIDNSVNKKDLSICGSSGEEFFNNCEVLQCGFSVPRENIRTRHKI------- 474 S +S+ K ++ SGE+ + CE +CG + + T HK+ Sbjct: 727 ------AFSQSSSLRKHEII---HSGEKPYK-CE--ECGKAFKWLSKLTVHKVIHTAEKP 774 Query: 475 CPCDKCEKVFPSISKLKRHYLIHTGQRPFGCNICGKSFRQSAHLKRHEQTHNEKSPY-AS 533 C C++C K F S L++H +IHTG++P+ C CGK+F S+ L +H+ H K PY + Sbjct: 775 CKCEECGKAFKHFSALRKHKIIHTGKKPYKCEECGKAFNDSSTLMKHKIIHTGKKPYKCA 834 Query: 534 LCQVEFGNFNNLSNHSGNNVNYNASQQCQAPGVQKYEVSESDQMSGVKAESQDFIPGSTG 593 C F ++L+ H + G + Y+ E +DF ST Sbjct: 835 ECGKAFKQSSHLTRHKAIHT-----------GEKPYKCEEC---------GKDFNNSST- 873 Query: 594 QPCLPNVLLESEQSNPFCSYSEHQEKNDVFLYRCSVCAKSFRSPSKLERHYLIHAGQKPF 653 + L+ + + LY+C C K+F + S L +H +IH G+KP+ Sbjct: 874 --LKKHKLIHTREK----------------LYKCEECVKAFNNFSALMKHKIIHTGEKPY 915 Query: 654 ECSVCGKTFRQAPHWKRHQLTHFKERP 680 +C CGK F+ + H++ H E+P Sbjct: 916 KCEECGKAFKWSSKLTEHKVIHTGEKP 942 Score = 249 bits (635), Expect = 8e-66 Identities = 196/711 (27%), Positives = 307/711 (43%), Gaps = 92/711 (12%) Query: 25 RPYVCNICFKHFETPSKLARHYLIHTGQKPFECDVCHKTFRQLVHLERHQLTHSLP--FK 82 +PY C C K F+ SKL H +IHTG+KP +C+ C K F+ L +H++ H+ +K Sbjct: 409 KPYKCEECGKAFKWSSKLTVHKVIHTGEKPCKCEECGKAFKHFSALRKHKVIHTREKLYK 468 Query: 83 CSICQRHFKNLKTFVKHQQLHNETYQNNVKQVRRLLEAKQEKSMYGVYNTFTTEERWALH 142 C C + F N KH+ +H ++ + + + +T E+ + Sbjct: 469 CEECGKAFNNSSILAKHKIIHTGKKPYKCEECGKAFRQSSHLTRHKAIHT--GEKPYKCE 526 Query: 143 PCSKSDPMYS-MKRRKNIHA------CTICGKMFPSQSKLDRHVLIHTGQRPFKCVLCTK 195 C K+ +S ++R K IH C CGK F S L RH +IHTG++P+KC C K Sbjct: 527 ECGKAFSHFSALRRHKIIHTGKKPYKCEECGKAFSHFSALRRHKIIHTGEKPYKCEECGK 586 Query: 196 SFRQSTHLKIHQLTHSEERPFQCCFCQKGFKIQSKLLKHKQIHTRNKAFRAL-LLKKRRT 254 +F+ S+ L +H++ H+ E+P +C C K FK S L KHK IHTR K ++ +K + Sbjct: 587 AFKWSSKLTVHKVIHTAEKPCKCEECGKSFKHFSALRKHKVIHTREKLYKCEECVKAFNS 646 Query: 255 ESRPLPNK-LNANQGGFENGEIGESEE-NNPLDVHSIYIV-------------------- 292 S + +K ++ + ++ E G++ + ++ L VH + Sbjct: 647 FSALMKHKVIHTGEKPYKCEECGKAFKWSSKLTVHKVIHTGEKPCKCEECGKAFKHFSAL 706 Query: 293 -----------PFQCPKCEKCFESEQILNEHSCFAARSGKIPSRFKRSYN-YKTIVKKIL 340 P++C +C K F L +H SG+ P + + +K + K + Sbjct: 707 RKHKVIHTGKKPYKCEECGKAFSQSSSLRKHEII--HSGEKPYKCEECGKAFKWLSKLTV 764 Query: 341 AKLKRARSKKLDNFQSEKKVFKKSFLRNCDLI-SGEQ--SSEQTQRTFVGS--LGKHGTY 395 K+ K + K S LR +I +G++ E+ + F S L KH Sbjct: 765 HKVIHTAEKPCKCEECGKAFKHFSALRKHKIIHTGKKPYKCEECGKAFNDSSTLMKH--- 821 Query: 396 KTIGNRKKKTLTLPFSWQNMGKNLKGILTTENILSIDNSVNKKDLSICGSSGEEFFNNCE 455 K I KK P+ GK K +I CG FNN Sbjct: 822 KIIHTGKK-----PYKCAECGKAFKQSSHLTRHKAIHTGEKPYKCEECGKD----FNNSS 872 Query: 456 VLQCGFSVPRENIRTRHKICPCDKCEKVFPSISKLKRHYLIHTGQRPFGCNICGKSFRQS 515 L+ + I TR K+ C++C K F + S L +H +IHTG++P+ C CGK+F+ S Sbjct: 873 TLK-----KHKLIHTREKLYKCEECVKAFNNFSALMKHKIIHTGEKPYKCEECGKAFKWS 927 Query: 516 AHLKRHEQTH-NEKSPYASLCQVEFGNFNNLSNHSGNNVNYNASQQCQAPGVQKYEVSES 574 + L H+ H EK C F +F+ L H + QC E ++ Sbjct: 928 SKLTEHKVIHTGEKPCKCEECDKAFKHFSALRKHKVIHTG-KKPYQCD-------ECGKA 979 Query: 575 DQMSGVKAESQDFIPGSTGQPCLPNVLLESEQSNPFCSYSEHQEKNDVF-----LYRCSV 629 S + + G C E+ S S K+ + Y+C Sbjct: 980 FNNSSTLTKHKIIHTGEKPYKC--------EECGKAFSQSSILTKHKIIHSVEKPYKCEE 1031 Query: 630 CAKSFRSPSKLERHYLIHAGQKPFECSVCGKTFRQAPHWKRHQLTHFKERP 680 C K+F S L RH IH G+KP++C CGK F Q + RH+ H +E+P Sbjct: 1032 CGKAFNQSSHLTRHKTIHTGEKPYKCEECGKAFIQCSYLIRHKTIHTREKP 1082 Score = 217 bits (553), Expect = 3e-56 Identities = 194/732 (26%), Positives = 315/732 (43%), Gaps = 111/732 (15%) Query: 11 KIQQCVVANKLPRNRPYVCNICFKHFETPSKLARHYLIHTGQKPFECDVCHKTFRQLVHL 70 K+ QC A + + + CN K F S R+ + HT +K F+C C K+F L L Sbjct: 8 KLNQCRTATQ---RKIFQCNKHMKVFHKYSN--RNKVRHTKKKTFKCIKCSKSFFMLSCL 62 Query: 71 ERHQLTHSLP--FKCSICQRHFKNLKTFVKHQQLHNETYQNNVKQVRRLLEAKQEKSMYG 128 RH+ H +KC + FK+ T KH+ +H E K+ + Sbjct: 63 IRHKRIHIRQNIYKCEERGKAFKSFSTLTKHKIIHTEDKPYKYKKCGNAFKFS------- 115 Query: 129 VYNTFTTEERWALHPCSKSDPMYSMKRRKNIHACTICGKMFPSQSKLDRHVLIHTGQRPF 188 +TFT +R + + C CGK F S L H IHTG++ + Sbjct: 116 --STFTKHKR--------------IHTGETPFRCEECGKAFNQSSNLTDHKRIHTGEKTY 159 Query: 189 KCVLCTKSFRQSTHLKIHQLTHSEERPFQCCFCQKGFKIQSKLLKHKQIHTRNKAFRALL 248 KC C K+F+ S++ H++ H+ E+P++C C K F S L KHK IHT K ++ Sbjct: 160 KCEECGKAFKGSSNFNAHKVIHTAEKPYKCEDCGKTFNHFSALRKHKIIHTGKKPYKREE 219 Query: 249 LKKRRTESRPLPNK--LNANQGGFENGEIGES-EENNPLDVHSIYIV---PFQCPKCEKC 302 K ++S L ++ + ++ E G++ + ++ L VH + P++C +C K Sbjct: 220 CGKAFSQSSTLRKHEIIHTGEKPYKCEECGKAFKWSSKLTVHKVVHTGEKPYKCEECGKA 279 Query: 303 FESEQILNEHSCFAARSGKIPSRFK---RSYNYKTIVKKILAKLKRARSKKLDNFQSEKK 359 F L +H +GK P + + +++N + + K K+ K + K Sbjct: 280 FSQFSTLKKHKII--HTGKKPYKCEECGKAFNSSSTLMK--HKIIHTGEKPYKCEECGKA 335 Query: 360 VFKKSFL-RNCDLISGEQ--SSEQTQRTF--VGSLGKHGTYKTIGNRKKKTLTLPFSWQN 414 + S L R+ + +GE+ E+ + F L +H K I KK P+ + Sbjct: 336 FRQSSHLTRHKAIHTGEKPYKCEECGKAFNHFSDLRRH---KIIHTGKK-----PYKCEE 387 Query: 415 MGKNLKGILTTENILSIDNSVNKKDLSICGS---------------SGEEFFNNCEVLQC 459 GK T N I CG +GE+ C+ +C Sbjct: 388 CGKAFSQSSTLRNHQIIHTGEKPYKCEECGKAFKWSSKLTVHKVIHTGEK---PCKCEEC 444 Query: 460 G-----FSVPREN--IRTRHKICPCDKCEKVFPSISKLKRHYLIHTGQRPFGCNICGKSF 512 G FS R++ I TR K+ C++C K F + S L +H +IHTG++P+ C CGK+F Sbjct: 445 GKAFKHFSALRKHKVIHTREKLYKCEECGKAFNNSSILAKHKIIHTGKKPYKCEECGKAF 504 Query: 513 RQSAHLKRHEQTHNEKSPY-ASLCQVEFGNFNNLSNHS---GNNVNYNASQQCQA----- 563 RQS+HL RH+ H + PY C F +F+ L H Y + +A Sbjct: 505 RQSSHLTRHKAIHTGEKPYKCEECGKAFSHFSALRRHKIIHTGKKPYKCEECGKAFSHFS 564 Query: 564 ---------PGVQKYEVSESDQMSGVKAE-SQDFIPGSTGQPCLPNVLLESEQSNPFCSY 613 G + Y+ E + ++ + + + +PC + E+ + Sbjct: 565 ALRRHKIIHTGEKPYKCEECGKAFKWSSKLTVHKVIHTAEKPC------KCEECGKSFKH 618 Query: 614 SEHQEKNDVF-----LYRCSVCAKSFRSPSKLERHYLIHAGQKPFECSVCGKTFRQAPHW 668 K+ V LY+C C K+F S S L +H +IH G+KP++C CGK F+ + Sbjct: 619 FSALRKHKVIHTREKLYKCEECVKAFNSFSALMKHKVIHTGEKPYKCEECGKAFKWSSKL 678 Query: 669 KRHQLTHFKERP 680 H++ H E+P Sbjct: 679 TVHKVIHTGEKP 690 Score = 177 bits (448), Expect = 4e-44 Identities = 147/536 (27%), Positives = 242/536 (45%), Gaps = 80/536 (14%) Query: 8 KMLKIQQCVVA----NKLPRNR-------PYVCNICFKHFETPSKLARHYLIHTGQKPFE 56 K+ K ++CV A + L +++ PY C C K F+ SKL H +IHTG+KP + Sbjct: 633 KLYKCEECVKAFNSFSALMKHKVIHTGEKPYKCEECGKAFKWSSKLTVHKVIHTGEKPCK 692 Query: 57 CDVCHKTFRQLVHLERHQLTHS--LPFKCSICQRHFKNLKTFVKHQQLHNETYQNNVKQV 114 C+ C K F+ L +H++ H+ P+KC C + F + KH+ +H+ ++ Sbjct: 693 CEECGKAFKHFSALRKHKVIHTGKKPYKCEECGKAFSQSSSLRKHEIIHSGEKPYKCEEC 752 Query: 115 RRLLEAKQEKSMYGVYNTFTTEERWALHPCSKSDPMYS-MKRRKNIHA------CTICGK 167 + + + +++ V +T E+ C K+ +S +++ K IH C CGK Sbjct: 753 GKAFKWLSKLTVHKVIHT--AEKPCKCEECGKAFKHFSALRKHKIIHTGKKPYKCEECGK 810 Query: 168 MFPSQSKLDRHVLIHTGQRPFKCVLCTKSFRQSTHLKIHQLTHSEERPFQCCFCQKGFKI 227 F S L +H +IHTG++P+KC C K+F+QS+HL H+ H+ E+P++C C K F Sbjct: 811 AFNDSSTLMKHKIIHTGKKPYKCAECGKAFKQSSHLTRHKAIHTGEKPYKCEECGKDFNN 870 Query: 228 QSKLLKHKQIHTRNKAFRAL-LLKKRRTESRPLPNKLNANQGGFENGEIGESEENNPLDV 286 S L KHK IHTR K ++ +K S + +K+ GE Sbjct: 871 SSTLKKHKLIHTREKLYKCEECVKAFNNFSALMKHKI------IHTGE------------ 912 Query: 287 HSIYIVPFQCPKCEKCFESEQILNEHSCFAARSGKIPSRFK---RSYNYKTIVKKILAKL 343 P++C +C K F+ L EH +G+ P + + +++ + + ++K K+ Sbjct: 913 -----KPYKCEECGKAFKWSSKLTEHKVI--HTGEKPCKCEECDKAFKHFSALRK--HKV 963 Query: 344 KRARSKKLDNFQSEKKVFKKSFLRNCDLI-SGEQ--SSEQTQRTFVGS--LGKHGTYKTI 398 K + K S L +I +GE+ E+ + F S L KH K I Sbjct: 964 IHTGKKPYQCDECGKAFNNSSTLTKHKIIHTGEKPYKCEECGKAFSQSSILTKH---KII 1020 Query: 399 GNRKKKTLTLPFSWQNMGK--NLKGILTTENILSIDNSVNKKDLSICGSSGEEFFNNCEV 456 + +K P+ + GK N LT + K C G+ F Sbjct: 1021 HSVEK-----PYKCEECGKAFNQSSHLTRHKTIHTGEKPYK-----CEECGKAF------ 1064 Query: 457 LQCGFSVPRENIRTRHKICPCDKCEKVFPSISKLKRHYLIHTGQRPFGCNICGKSF 512 +QC + + + I TR K K K+ + L IHTG++P+ C C K+F Sbjct: 1065 IQCSYLIRHKTIHTREKPTNVKKVPKLLSNPHTLLDK-TIHTGEKPYKCEECAKAF 1119 >gi|118600985 zinc finger protein 91 [Homo sapiens] Length = 1191 Score = 245 bits (625), Expect = 1e-64 Identities = 186/688 (27%), Positives = 298/688 (43%), Gaps = 74/688 (10%) Query: 25 RPYVCNICFKHFETPSKLARHYLIHTGQKPFECDVCHKTFRQLVHLERHQLTHSL--PFK 82 +PY C C K F S L +H +IHTG+KP++ + C K FRQ + L +H++ HS P+K Sbjct: 488 KPYKCEECGKAFRQSSTLTKHKIIHTGEKPYKFEECGKAFRQSLTLNKHKIIHSREKPYK 547 Query: 83 CSICQRHFKNLKTFVKHQQLHNETYQNNVKQVRRLLEAKQEKSMYGVYNTFTTEERWALH 142 C C + FK T H+ +H ++ + S + + +T E+ + Sbjct: 548 CKECGKAFKQFSTLTTHKIIHAGKKLYKCEECGKAFNHSSSLSTHKIIHT--GEKSYKCE 605 Query: 143 PCSKSDPMYS-MKRRKNIHA------CTICGKMFPSQSKLDRHVLIHTGQRPFKCVLCTK 195 C K+ S ++R K IH C CGK F S L +H IHTG++P+KC C K Sbjct: 606 ECGKAFLWSSTLRRHKRIHTGEKPYKCEECGKAFSHSSALAKHKRIHTGEKPYKCKECGK 665 Query: 196 SFRQSTHLKIHQLTHSEERPFQCCFCQKGFKIQSKLLKHKQIHTRNKAFRALLLKK--RR 253 +F S+ L H++TH+EE+P++C C K FK S L KHK IH K ++ K R Sbjct: 666 AFSNSSTLANHKITHTEEKPYKCKECDKTFKRLSTLTKHKIIHAGEKLYKCEECGKAFNR 725 Query: 254 TESRPLPNKLNANQGGFENGEIGESEE-NNPLDVHSIYIV---PFQCPKCEKCFESEQIL 309 + + + ++ + ++ E G++ ++ L H PF+C +C K F L Sbjct: 726 SSNLTIHKFIHTGEKPYKCEECGKAFNWSSSLTKHKRIHTREKPFKCKECGKAFIWSSTL 785 Query: 310 NEHSCF--------AARSGKIPSRFKRSYNYKTIVKKILAKLKRARSKKLDNFQSEKKVF 361 H GK SR +KTI +K + K F Sbjct: 786 TRHKRIHTGEKPYKCEECGKAFSRSSTLTKHKTI----------HTGEKPYKCKECGKAF 835 Query: 362 KKS--FLRNCDLISGEQ--SSEQTQRTFVGSLGKHGTYKTIGNRKKKTLT----LPFSWQ 413 K S ++ + +GE+ E+ + F S T+K I ++K + + F W Sbjct: 836 KHSSALAKHKIIHAGEKLYKCEECGKAFNQS-SNLTTHKIIHTKEKPSKSEECDKAFIWS 894 Query: 414 NMGKNLKGILTTENILSIDNSVNKKDLSICGSSGEEFFNNCEVLQCGFSVPRENIRTRHK 473 + K I T E C G+ F Q + + T K Sbjct: 895 STLTEHKRIHTREKTYK------------CEECGKAFS------QPSHLTTHKRMHTGEK 936 Query: 474 ICPCDKCEKVFPSISKLKRHYLIHTGQRPFGCNICGKSFRQSAHLKRHEQTHNEKSPY-A 532 C++C K F S L H +IHTG++P+ C CGK+FR+S+ L H+ H + PY Sbjct: 937 PYKCEECGKAFSQSSTLTTHKIIHTGEKPYKCEECGKAFRKSSTLTEHKIIHTGEKPYKC 996 Query: 533 SLCQVEFGNFNNLSNHSGNNVNYNASQQCQAPGVQKYEVSESDQMSGVKAESQDFIPGST 592 C F + L+ H+ + +C+ G S+ + + + Sbjct: 997 EECGKAFSQSSTLTRHTRMHTG-EKPYKCEECGKAFNRSSKLTTHKIIHTGEKPYKCEEC 1055 Query: 593 GQPCLPNVLLESEQSNPFCSYSEHQEKNDVFLYRCSVCAKSFRSPSKLERHYLIHAGQKP 652 G+ + + L + +EK Y+C C K+F S L RH +H G+KP Sbjct: 1056 GKAFISSSTLNGHKR------IHTREKP----YKCEECGKAFSQSSTLTRHKRLHTGEKP 1105 Query: 653 FECSVCGKTFRQAPHWKRHQLTHFKERP 680 ++C CGK F+++ +H++ H E+P Sbjct: 1106 YKCGECGKAFKESSALTKHKIIHTGEKP 1133 Score = 232 bits (591), Expect = 1e-60 Identities = 193/729 (26%), Positives = 306/729 (41%), Gaps = 96/729 (13%) Query: 23 RNRPYVCNICFKHFETPSKLARHYLIHTGQKPFECDVCHKTFRQLVHLERHQLTHS--LP 80 + + Y C C K F S L RH IHTG+KP++C+ C K F L +H+ H+ P Sbjct: 262 KEKIYKCEECGKAFLWSSTLTRHKRIHTGEKPYKCEECGKAFSHSSTLAKHKRIHTGEKP 321 Query: 81 FKCSICQRHFKNLKTFVKHQQLHNETYQNNVKQVRRLLEAKQEKSMYGVYNTFTTEERWA 140 +KC C + F T KH+++H K+ + + + + T T E+ + Sbjct: 322 YKCEECGKAFSRSSTLAKHKRIHTGEKPYKCKECGKAFSNSSTLANHKI--THTEEKPYK 379 Query: 141 LHPCSKSDPMYS-MKRRKNIHA------CTICGKMFPSQSKLDRHVLIHTGQRPFKCVLC 193 C K+ S + + K IHA C CGK F S L H IHTG++P+KC C Sbjct: 380 CKECDKAFKRLSTLTKHKIIHAGEKLYKCEECGKAFNRSSNLTIHKFIHTGEKPYKCEEC 439 Query: 194 TKSFRQSTHLKIHQLTHSEERPFQCCFCQKGFKIQSKLLKHKQIHTRNKAFRALLLKKRR 253 K+F S+ L H+ H+ E+PF+C C K F S L +HK+IHT K ++ K Sbjct: 440 GKAFNWSSSLTKHKRFHTREKPFKCKECGKAFIWSSTLTRHKRIHTGEKPYKCEECGKAF 499 Query: 254 TESRPLPNK--LNANQGGFENGEIGES-EENNPLDVHSIY---IVPFQCPKCEKCFESEQ 307 +S L ++ + ++ E G++ ++ L+ H I P++C +C K F+ Sbjct: 500 RQSSTLTKHKIIHTGEKPYKFEECGKAFRQSLTLNKHKIIHSREKPYKCKECGKAFKQFS 559 Query: 308 ILNEHSCFAA--------------------RSGKIPSRFKRSYNYKTIVKKILAKLKRAR 347 L H A + KI ++SY + K L R Sbjct: 560 TLTTHKIIHAGKKLYKCEECGKAFNHSSSLSTHKIIHTGEKSYKCEECGKAFLWSSTLRR 619 Query: 348 SKKLDNFQSEKKVFK--KSFLRNCDLISGEQSSEQTQRTFVGSLGK-HGTYKTIGNRK-K 403 K++ + K + K+F + L ++ + GK T+ N K Sbjct: 620 HKRIHTGEKPYKCEECGKAFSHSSALAKHKRIHTGEKPYKCKECGKAFSNSSTLANHKIT 679 Query: 404 KTLTLPFSWQNMGKNLKGI--LTTENILSIDNSVNKKDLSICGSSGEEFFN--------- 452 T P+ + K K + LT I+ + K CG + N Sbjct: 680 HTEEKPYKCKECDKTFKRLSTLTKHKIIHAGEKLYK--CEECGKAFNRSSNLTIHKFIHT 737 Query: 453 -----NCEVLQCGFS-------VPRENIRTRHKICPCDKCEKVFPSISKLKRHYLIHTGQ 500 CE +CG + + I TR K C +C K F S L RH IHTG+ Sbjct: 738 GEKPYKCE--ECGKAFNWSSSLTKHKRIHTREKPFKCKECGKAFIWSSTLTRHKRIHTGE 795 Query: 501 RPFGCNICGKSFRQSAHLKRHEQTHNEKSPY-ASLCQVEFGNFNNLSNHSGNNVNYN--A 557 +P+ C CGK+F +S+ L +H+ H + PY C F + + L+ H + Sbjct: 796 KPYKCEECGKAFSRSSTLTKHKTIHTGEKPYKCKECGKAFKHSSALAKHKIIHAGEKLYK 855 Query: 558 SQQC-----QAPGVQKYEVSESDQMSGVKAE-SQDFIPGSTGQPCLPNVLLESEQSNPFC 611 ++C Q+ + +++ + + E + FI ST L E ++ + Sbjct: 856 CEECGKAFNQSSNLTTHKIIHTKEKPSKSEECDKAFIWSST--------LTEHKRIHT-- 905 Query: 612 SYSEHQEKNDVFLYRCSVCAKSFRSPSKLERHYLIHAGQKPFECSVCGKTFRQAPHWKRH 671 +EK Y+C C K+F PS L H +H G+KP++C CGK F Q+ H Sbjct: 906 -----REKT----YKCEECGKAFSQPSHLTTHKRMHTGEKPYKCEECGKAFSQSSTLTTH 956 Query: 672 QLTHFKERP 680 ++ H E+P Sbjct: 957 KIIHTGEKP 965 Score = 229 bits (583), Expect = 8e-60 Identities = 192/721 (26%), Positives = 309/721 (42%), Gaps = 84/721 (11%) Query: 25 RPYVCNICFKHFETPSKLARHYLIHTGQKPFECDVCHKTFRQLVHLERHQLTHS--LPFK 82 +PY C C K F S LA+H IHTG+KP++C C K F L H++TH+ P+K Sbjct: 320 KPYKCEECGKAFSRSSTLAKHKRIHTGEKPYKCKECGKAFSNSSTLANHKITHTEEKPYK 379 Query: 83 CSICQRHFKNLKTFVKHQQLHNETYQNNVKQVRRLLEAKQEKSMYGVYNTFTTEERWALH 142 C C + FK L T KH+ +H ++ + +++ +T E+ + Sbjct: 380 CKECDKAFKRLSTLTKHKIIHAGEKLYKCEECGKAFNRSSNLTIHKFIHT--GEKPYKCE 437 Query: 143 PCSKS-DPMYSMKRRKNIHA------CTICGKMFPSQSKLDRHVLIHTGQRPFKCVLCTK 195 C K+ + S+ + K H C CGK F S L RH IHTG++P+KC C K Sbjct: 438 ECGKAFNWSSSLTKHKRFHTREKPFKCKECGKAFIWSSTLTRHKRIHTGEKPYKCEECGK 497 Query: 196 SFRQSTHLKIHQLTHSEERPFQCCFCQKGFKIQSKLLKHKQIHTRNKAFRALLLKKRRTE 255 +FRQS+ L H++ H+ E+P++ C K F+ L KHK IH+R K ++ K + Sbjct: 498 AFRQSSTLTKHKIIHTGEKPYKFEECGKAFRQSLTLNKHKIIHSREKPYKCKECGKAFKQ 557 Query: 256 SRPLPNK--LNANQGGFENGEIGES-EENNPLDVHSIYIV---PFQCPKCEKCFESEQIL 309 L ++A + ++ E G++ ++ L H I ++C +C K F L Sbjct: 558 FSTLTTHKIIHAGKKLYKCEECGKAFNHSSSLSTHKIIHTGEKSYKCEECGKAFLWSSTL 617 Query: 310 NEHSCFAARSGKIPSRFK---RSYNYKTIVKKILAKLKRARS--KKLDNFQSEKKVFKKS 364 H +G+ P + + +++++ + LAK KR + K + K S Sbjct: 618 RRHK--RIHTGEKPYKCEECGKAFSHSSA----LAKHKRIHTGEKPYKCKECGKAFSNSS 671 Query: 365 FLRNCDLISGEQSS---EQTQRTF--VGSLGKHGT-------YKTI----GNRKKKTLTL 408 L N + E+ ++ +TF + +L KH YK + LT+ Sbjct: 672 TLANHKITHTEEKPYKCKECDKTFKRLSTLTKHKIIHAGEKLYKCEECGKAFNRSSNLTI 731 Query: 409 ---------PFSWQNMGK--NLKGILTTENILSIDNSVNKKDLSICGSSGEEFFNNCEVL 457 P+ + GK N LT + K C G+ F + + Sbjct: 732 HKFIHTGEKPYKCEECGKAFNWSSSLTKHKRIHTREKPFK-----CKECGKAFIWSSTLT 786 Query: 458 QCGFSVPRENIRTRHKICPCDKCEKVFPSISKLKRHYLIHTGQRPFGCNICGKSFRQSAH 517 + + I T K C++C K F S L +H IHTG++P+ C CGK+F+ S+ Sbjct: 787 R------HKRIHTGEKPYKCEECGKAFSRSSTLTKHKTIHTGEKPYKCKECGKAFKHSSA 840 Query: 518 LKRHEQTH-NEKSPYASLCQVEFGNFNNLSNHS--GNNVNYNASQQCQAPGVQKYEVSES 574 L +H+ H EK C F +NL+ H + S++C + ++E Sbjct: 841 LAKHKIIHAGEKLYKCEECGKAFNQSSNLTTHKIIHTKEKPSKSEECDKAFIWSSTLTEH 900 Query: 575 DQMSGV----------KAESQDFIPGSTGQPCLPNVLLESEQSNPFCSYSEHQEKNDVFL 624 ++ KA SQ + + + E+ S S + + Sbjct: 901 KRIHTREKTYKCEECGKAFSQPSHLTTHKRMHTGEKPYKCEECGKAFSQSSTLTTHKIIH 960 Query: 625 -----YRCSVCAKSFRSPSKLERHYLIHAGQKPFECSVCGKTFRQAPHWKRHQLTHFKER 679 Y+C C K+FR S L H +IH G+KP++C CGK F Q+ RH H E+ Sbjct: 961 TGEKPYKCEECGKAFRKSSTLTEHKIIHTGEKPYKCEECGKAFSQSSTLTRHTRMHTGEK 1020 Query: 680 P 680 P Sbjct: 1021 P 1021 Score = 222 bits (565), Expect = 1e-57 Identities = 179/680 (26%), Positives = 283/680 (41%), Gaps = 128/680 (18%) Query: 27 YVCNICFKHFETPSKLARHYLIHTGQKPFECDVCHKTFRQLVHLERHQLTHS--LPFKCS 84 Y C C K F S L+ H +IHTG+K ++C+ C K F L RH+ H+ P+KC Sbjct: 574 YKCEECGKAFNHSSSLSTHKIIHTGEKSYKCEECGKAFLWSSTLRRHKRIHTGEKPYKCE 633 Query: 85 ICQRHFKNLKTFVKHQQLHNETYQNNVKQVRRLLEAKQEKSMYGVYNTFTTEERWALHPC 144 C + F + KH+++H K+ + + + + T T E+ + C Sbjct: 634 ECGKAFSHSSALAKHKRIHTGEKPYKCKECGKAFSNSSTLANHKI--THTEEKPYKCKEC 691 Query: 145 SKSDPMYS-MKRRKNIHA------CTICGKMFPSQSKLDRHVLIHTGQRPFKCVLCTKSF 197 K+ S + + K IHA C CGK F S L H IHTG++P+KC C K+F Sbjct: 692 DKTFKRLSTLTKHKIIHAGEKLYKCEECGKAFNRSSNLTIHKFIHTGEKPYKCEECGKAF 751 Query: 198 RQSTHLKIHQLTHSEERPFQCCFCQKGFKIQSKLLKHKQIHTRNKAFRALLLKKRRTESR 257 S+ L H+ H+ E+PF+C C K F S L +HK+IHT K ++ K + S Sbjct: 752 NWSSSLTKHKRIHTREKPFKCKECGKAFIWSSTLTRHKRIHTGEKPYKCEECGKAFSRSS 811 Query: 258 PLPNKLNANQGGFENGEIGESEENNPLDVHSIYIVPFQCPKCEKCFESEQILNEHSCFAA 317 L + G P++C +C K F+ L +H A Sbjct: 812 TLTKHKTIHTGE----------------------KPYKCKECGKAFKHSSALAKHKIIHA 849 Query: 318 -----RSGKIPSRFKRSYNYKTIVKKILAKLKRARSKKLD-------NFQSEKKVFKKSF 365 + + F +S N T K I K K ++S++ D K++ + Sbjct: 850 GEKLYKCEECGKAFNQSSNL-TTHKIIHTKEKPSKSEECDKAFIWSSTLTEHKRIHTREK 908 Query: 366 LRNCDLISGEQSSEQTQRTFVGSLGKHGTYKTIGNRKKKTLTLPFSWQNMGK--NLKGIL 423 C+ G+ S+ + T T+K + +K P+ + GK + L Sbjct: 909 TYKCE-ECGKAFSQPSHLT---------THKRMHTGEK-----PYKCEECGKAFSQSSTL 953 Query: 424 TTENILSIDNSVNKKDLSICGSSGEEFFNNCEVLQCGFSVPRENIRTRHKIC-------P 476 TT I+ +GE+ + CE +CG + + + T HKI Sbjct: 954 TTHKII---------------HTGEKPY-KCE--ECGKAFRKSSTLTEHKIIHTGEKPYK 995 Query: 477 CDKCEKVFPSISKLKRHYLIHTGQRPFGCNICGKSFRQSAHLKRHEQTHNEKSPY-ASLC 535 C++C K F S L RH +HTG++P+ C CGK+F +S+ L H+ H + PY C Sbjct: 996 CEECGKAFSQSSTLTRHTRMHTGEKPYKCEECGKAFNRSSKLTTHKIIHTGEKPYKCEEC 1055 Query: 536 QVEFGNFNNLSNHSGNNVNYNASQQCQAPGVQKYEVSESDQMSGVKAESQDFIPGSTGQP 595 F + + L+ H + +C+ G S+S ++ K TG+ Sbjct: 1056 GKAFISSSTLNGHKRIHTR-EKPYKCEECG---KAFSQSSTLTRHKRL-------HTGE- 1103 Query: 596 CLPNVLLESEQSNPFCSYSEHQEKNDVFLYRCSVCAKSFRSPSKLERHYLIHAGQKPFEC 655 P+ +C C K+F+ S L +H +IH G+KP++C Sbjct: 1104 ------------KPY---------------KCGECGKAFKESSALTKHKIIHTGEKPYKC 1136 Query: 656 SVCGKTFRQAPHWKRHQLTH 675 CGK F Q+ H+ H Sbjct: 1137 EKCGKAFNQSSILTNHKKIH 1156 Score = 219 bits (559), Expect = 5e-57 Identities = 176/704 (25%), Positives = 298/704 (42%), Gaps = 109/704 (15%) Query: 11 KIQQCVVANKLPRNRPYVCNICFKHFETPSKLARHYLIHTGQKPFECDVCHKTFRQLVHL 70 K+ QC+ +++ + C K F RH + HTG+K F+C C K+F +H Sbjct: 141 KLNQCLTT---AQSKVFQCGKYLKVFYKFLNSNRHTIRHTGKKCFKCKKCVKSFCIRLHK 197 Query: 71 ERHQLTH--SLPFKCSICQRHFKNLKTFVKHQQLHNETYQNNVKQVRRLLEAKQEKSMYG 128 +H+ + KC C++ F T H+++H E ++ + A ++ S Sbjct: 198 TQHKCVYITEKSCKCKECEKTFHWSSTLTNHKEIHTEDKPYKCEECGK---AFKQLSTLT 254 Query: 129 VYNTFTTEERWALHPCSKSDPMY----SMKRRKNIHA------CTICGKMFPSQSKLDRH 178 + +E+ ++ C + + ++ R K IH C CGK F S L +H Sbjct: 255 THKIICAKEK--IYKCEECGKAFLWSSTLTRHKRIHTGEKPYKCEECGKAFSHSSTLAKH 312 Query: 179 VLIHTGQRPFKCVLCTKSFRQSTHLKIHQLTHSEERPFQCCFCQKGFKIQSKLLKHKQIH 238 IHTG++P+KC C K+F +S+ L H+ H+ E+P++C C K F S L HK H Sbjct: 313 KRIHTGEKPYKCEECGKAFSRSSTLAKHKRIHTGEKPYKCKECGKAFSNSSTLANHKITH 372 Query: 239 TRNKAFRALLLKK--RRTESRPLPNKLNANQGGFENGEIGES-EENNPLDVHSIYIV--- 292 T K ++ K +R + ++A + ++ E G++ ++ L +H Sbjct: 373 TEEKPYKCKECDKAFKRLSTLTKHKIIHAGEKLYKCEECGKAFNRSSNLTIHKFIHTGEK 432 Query: 293 PFQCPKCEKCFESEQILNEHSCFAARSGKIPSRFKRSYNYKTIVKKILAKLKRARSKKLD 352 P++C +C K F L +H F R ++ + K K + R K++ Sbjct: 433 PYKCEECGKAFNWSSSLTKHKRFHTR--------EKPFKCKECGKAFIWSSTLTRHKRIH 484 Query: 353 NFQSEKKVFK--KSFLRNCDLISGEQSSEQTQRTFVGSLGKHGTYKTIGNRKKKTLTL-- 408 + K + K+F QSS T+ + + K ++ G +++LTL Sbjct: 485 TGEKPYKCEECGKAF---------RQSSTLTKHKIIHTGEKPYKFEECGKAFRQSLTLNK 535 Query: 409 ---------PFSWQNMGKNLK--GILTTENILSIDNSVNKKDLSICGSSGEEFFNNCEVL 457 P+ + GK K LTT I+ + K C G+ F ++ + Sbjct: 536 HKIIHSREKPYKCKECGKAFKQFSTLTTHKIIHAGKKLYK-----CEECGKAFNHSSSL- 589 Query: 458 QCGFSVPRENIRTRHKICPCDKCEKVFPSISKLKRHYLIHTGQRPFGCNICGKSFRQSAH 517 + I T K C++C K F S L+RH IHTG++P+ C CGK+F S+ Sbjct: 590 -----STHKIIHTGEKSYKCEECGKAFLWSSTLRRHKRIHTGEKPYKCEECGKAFSHSSA 644 Query: 518 LKRHEQTHNEKSPY-ASLCQVEFGNFNNLSNHSGNNVNYNASQQCQAPGVQKYEVSESDQ 576 L +H++ H + PY C F N + L+NH + + Y+ E D Sbjct: 645 LAKHKRIHTGEKPYKCKECGKAFSNSSTLANHKITHTE-----------EKPYKCKECD- 692 Query: 577 MSGVKAESQDFIPGSTGQPCLPNVLLESEQSNPFCSYSEHQEKNDVFLYRCSVCAKSFRS 636 + F ST + ++ + + LY+C C K+F Sbjct: 693 --------KTFKRLST---LTKHKIIHAGEK----------------LYKCEECGKAFNR 725 Query: 637 PSKLERHYLIHAGQKPFECSVCGKTFRQAPHWKRHQLTHFKERP 680 S L H IH G+KP++C CGK F + +H+ H +E+P Sbjct: 726 SSNLTIHKFIHTGEKPYKCEECGKAFNWSSSLTKHKRIHTREKP 769 Score = 157 bits (396), Expect = 4e-38 Identities = 93/305 (30%), Positives = 150/305 (49%), Gaps = 17/305 (5%) Query: 23 RNRPYVCNICFKHFETPSKLARHYLIHTGQKPFECDVCHKTFRQLVHLERHQLTHS--LP 80 R +P+ C C K F S L RH IHTG+KP++C+ C K F + L +H+ H+ P Sbjct: 766 REKPFKCKECGKAFIWSSTLTRHKRIHTGEKPYKCEECGKAFSRSSTLTKHKTIHTGEKP 825 Query: 81 FKCSICQRHFKNLKTFVKHQQLHNETYQNNVKQVRRLLEAKQEKSMYGVYNTFTTEERWA 140 +KC C + FK+ KH+ +H ++ + + + + + T E+ Sbjct: 826 YKCKECGKAFKHSSALAKHKIIHAGEKLYKCEECGKAFNQSSNLTTHKIIH--TKEKPSK 883 Query: 141 LHPCSK----SDPMYSMKR---RKNIHACTICGKMFPSQSKLDRHVLIHTGQRPFKCVLC 193 C K S + KR R+ + C CGK F S L H +HTG++P+KC C Sbjct: 884 SEECDKAFIWSSTLTEHKRIHTREKTYKCEECGKAFSQPSHLTTHKRMHTGEKPYKCEEC 943 Query: 194 TKSFRQSTHLKIHQLTHSEERPFQCCFCQKGFKIQSKLLKHKQIHTRNKAFRALLLKKRR 253 K+F QS+ L H++ H+ E+P++C C K F+ S L +HK IHT K ++ K Sbjct: 944 GKAFSQSSTLTTHKIIHTGEKPYKCEECGKAFRKSSTLTEHKIIHTGEKPYKCEECGKAF 1003 Query: 254 TESRPLP--NKLNANQGGFENGEIGES-EENNPLDVHSIYIV---PFQCPKCEKCFESEQ 307 ++S L +++ + ++ E G++ ++ L H I P++C +C K F S Sbjct: 1004 SQSSTLTRHTRMHTGEKPYKCEECGKAFNRSSKLTTHKIIHTGEKPYKCEECGKAFISSS 1063 Query: 308 ILNEH 312 LN H Sbjct: 1064 TLNGH 1068 Score = 153 bits (386), Expect = 6e-37 Identities = 99/329 (30%), Positives = 162/329 (49%), Gaps = 41/329 (12%) Query: 25 RPYVCNICFKHFETPSKLARHYLIHTGQKPFECDVCHKTFRQLVHLERHQLTHSL--PFK 82 +PY C C K F+ S LA+H +IH G+K ++C+ C K F Q +L H++ H+ P K Sbjct: 824 KPYKCKECGKAFKHSSALAKHKIIHAGEKLYKCEECGKAFNQSSNLTTHKIIHTKEKPSK 883 Query: 83 CSICQRHFKNLKTFVKHQQLHN--ETYQ-----------NNVKQVRRL------LEAKQE 123 C + F T +H+++H +TY+ +++ +R+ + ++ Sbjct: 884 SEECDKAFIWSSTLTEHKRIHTREKTYKCEECGKAFSQPSHLTTHKRMHTGEKPYKCEEC 943 Query: 124 KSMYGVYNTFTT-------EERWALHPCSKSDPMYS-MKRRKNIHA------CTICGKMF 169 + +T TT E+ + C K+ S + K IH C CGK F Sbjct: 944 GKAFSQSSTLTTHKIIHTGEKPYKCEECGKAFRKSSTLTEHKIIHTGEKPYKCEECGKAF 1003 Query: 170 PSQSKLDRHVLIHTGQRPFKCVLCTKSFRQSTHLKIHQLTHSEERPFQCCFCQKGFKIQS 229 S L RH +HTG++P+KC C K+F +S+ L H++ H+ E+P++C C K F S Sbjct: 1004 SQSSTLTRHTRMHTGEKPYKCEECGKAFNRSSKLTTHKIIHTGEKPYKCEECGKAFISSS 1063 Query: 230 KLLKHKQIHTRNKAFRALLLKKRRTESRPLP--NKLNANQGGFENGEIGES-EENNPLDV 286 L HK+IHTR K ++ K ++S L +L+ + ++ GE G++ +E++ L Sbjct: 1064 TLNGHKRIHTREKPYKCEECGKAFSQSSTLTRHKRLHTGEKPYKCGECGKAFKESSALTK 1123 Query: 287 HSIYIV---PFQCPKCEKCFESEQILNEH 312 H I P++C KC K F IL H Sbjct: 1124 HKIIHTGEKPYKCEKCGKAFNQSSILTNH 1152 Score = 147 bits (372), Expect = 2e-35 Identities = 145/613 (23%), Positives = 236/613 (38%), Gaps = 68/613 (11%) Query: 98 KHQQLHNETYQNNVKQVRRLLEAKQEKSMYGVYNTFTTEERWALHPCSKSDPMYSMKRRK 157 K+++ +E Q K + + E K K Y N T + + C K ++ Sbjct: 111 KYEKCGHENLQLR-KGCKSVDECKVHKEGYNKLNQCLTTAQSKVFQCGKYLKVFYKFLNS 169 Query: 158 NIHA----------CTICGKMFPSQSKLDRHVLIHTGQRPFKCVLCTKSFRQSTHLKIHQ 207 N H C C K F + +H ++ ++ KC C K+F S+ L H+ Sbjct: 170 NRHTIRHTGKKCFKCKKCVKSFCIRLHKTQHKCVYITEKSCKCKECEKTFHWSSTLTNHK 229 Query: 208 LTHSEERPFQCCFCQKGFKIQSKLLKHKQIHTRNKAFRALLLKKRRTESRPLP--NKLNA 265 H+E++P++C C K FK S L HK I + K ++ K S L +++ Sbjct: 230 EIHTEDKPYKCEECGKAFKQLSTLTTHKIICAKEKIYKCEECGKAFLWSSTLTRHKRIHT 289 Query: 266 NQGGFENGEIGES-EENNPLDVHSIYIV---PFQCPKCEKCFESEQILNEHSCF------ 315 + ++ E G++ ++ L H P++C +C K F L +H Sbjct: 290 GEKPYKCEECGKAFSHSSTLAKHKRIHTGEKPYKCEECGKAFSRSSTLAKHKRIHTGEKP 349 Query: 316 --AARSGKIPSRFKRSYNYK---TIVKKILAKLKRARSKKLDNFQSEKKVFKKSFLRNCD 370 GK S N+K T K K K+L K + L C+ Sbjct: 350 YKCKECGKAFSNSSTLANHKITHTEEKPYKCKECDKAFKRLSTLTKHKIIHAGEKLYKCE 409 Query: 371 LI--SGEQSSEQTQRTFVGSLGKHGTYKTIGNRKKKTLTLPFSWQNMGKNLKGILTTENI 428 + +SS T F+ + K + G F+W + K T E Sbjct: 410 ECGKAFNRSSNLTIHKFIHTGEKPYKCEECGK--------AFNWSSSLTKHKRFHTREKP 461 Query: 429 LSIDNSVNKKDLSICGSSGEEFFNNCEVLQCGFSVPRENIRTRHKICPCDKCEKVFPSIS 488 C G+ F + + + + I T K C++C K F S Sbjct: 462 FK------------CKECGKAFIWSSTLTR------HKRIHTGEKPYKCEECGKAFRQSS 503 Query: 489 KLKRHYLIHTGQRPFGCNICGKSFRQSAHLKRHEQTHNEKSPY-ASLCQVEFGNFNNLSN 547 L +H +IHTG++P+ CGK+FRQS L +H+ H+ + PY C F F+ L+ Sbjct: 504 TLTKHKIIHTGEKPYKFEECGKAFRQSLTLNKHKIIHSREKPYKCKECGKAFKQFSTLTT 563 Query: 548 HSGNNVNYNASQQCQAPGVQKYEVSESDQMSGVKAESQDFIPGSTGQPCLPNVLLESEQS 607 H + +C+ G S + + + G+ L + L + Sbjct: 564 HKIIHAG-KKLYKCEECGKAFNHSSSLSTHKIIHTGEKSYKCEECGKAFLWSSTLRRHKR 622 Query: 608 NPFCSYSEHQEKNDVFLYRCSVCAKSFRSPSKLERHYLIHAGQKPFECSVCGKTFRQAPH 667 EK Y+C C K+F S L +H IH G+KP++C CGK F + Sbjct: 623 ------IHTGEKP----YKCEECGKAFSHSSALAKHKRIHTGEKPYKCKECGKAFSNSST 672 Query: 668 WKRHQLTHFKERP 680 H++TH +E+P Sbjct: 673 LANHKITHTEEKP 685 Score = 145 bits (365), Expect = 2e-34 Identities = 74/224 (33%), Positives = 117/224 (52%), Gaps = 11/224 (4%) Query: 25 RPYVCNICFKHFETPSKLARHYLIHTGQKPFECDVCHKTFRQLVHLERHQLTHS--LPFK 82 +PY C C K F S L H +IHTG+KP++C+ C K FR+ L H++ H+ P+K Sbjct: 936 KPYKCEECGKAFSQSSTLTTHKIIHTGEKPYKCEECGKAFRKSSTLTEHKIIHTGEKPYK 995 Query: 83 CSICQRHFKNLKTFVKHQQLHNETYQNNVKQVRRLLEAKQEKSMYGVYNTFTTEERWALH 142 C C + F T +H ++H ++ + + + + + +T E+ + Sbjct: 996 CEECGKAFSQSSTLTRHTRMHTGEKPYKCEECGKAFNRSSKLTTHKIIHT--GEKPYKCE 1053 Query: 143 PCSK----SDPMYSMKR---RKNIHACTICGKMFPSQSKLDRHVLIHTGQRPFKCVLCTK 195 C K S + KR R+ + C CGK F S L RH +HTG++P+KC C K Sbjct: 1054 ECGKAFISSSTLNGHKRIHTREKPYKCEECGKAFSQSSTLTRHKRLHTGEKPYKCGECGK 1113 Query: 196 SFRQSTHLKIHQLTHSEERPFQCCFCQKGFKIQSKLLKHKQIHT 239 +F++S+ L H++ H+ E+P++C C K F S L HK+IHT Sbjct: 1114 AFKESSALTKHKIIHTGEKPYKCEKCGKAFNQSSILTNHKKIHT 1157 Score = 72.8 bits (177), Expect = 1e-12 Identities = 31/86 (36%), Positives = 47/86 (54%), Gaps = 2/86 (2%) Query: 23 RNRPYVCNICFKHFETPSKLARHYLIHTGQKPFECDVCHKTFRQLVHLERHQLTHS--LP 80 R +PY C C K F S L RH +HTG+KP++C C K F++ L +H++ H+ P Sbjct: 1074 REKPYKCEECGKAFSQSSTLTRHKRLHTGEKPYKCGECGKAFKESSALTKHKIIHTGEKP 1133 Query: 81 FKCSICQRHFKNLKTFVKHQQLHNET 106 +KC C + F H+++H T Sbjct: 1134 YKCEKCGKAFNQSSILTNHKKIHTIT 1159 >gi|210031219 zinc finger protein 845 [Homo sapiens] Length = 970 Score = 226 bits (577), Expect = 4e-59 Identities = 179/699 (25%), Positives = 300/699 (42%), Gaps = 106/699 (15%) Query: 25 RPYVCNICFKHFETPSKLARHYLIHTGQKPFECDVCHKTFRQLVHLERHQLTHS--LPFK 82 + Y CN C K F S L H +HTG+KP++C+ C K F +LERH+ H+ P+K Sbjct: 325 KSYKCNECGKTFSQTSYLVYHRRLHTGEKPYKCEECDKAFSFKSNLERHRKIHTGEKPYK 384 Query: 83 CSICQRHFKNLKTFVKHQQLHNETYQNNVKQVRRLLEAKQEKSMYGVYNTFTTEERWALH 142 C+ C R F + +H++LH T E+ + + Sbjct: 385 CNECSRTFSRKSSLTRHRRLH------------------------------TGEKPYKCN 414 Query: 143 PCSKS-DPMYSMKRRKNIHA------CTICGKMFPSQSKLDRHVLIHTGQRPFKCVLCTK 195 C K+ M S+ + +H C C + F +S L+RH IHTG++P+KC C K Sbjct: 415 DCGKTFSQMSSLVYHRRLHTGEKPYKCEECDEAFSFKSNLERHRRIHTGEKPYKCNDCGK 474 Query: 196 SFRQSTHLKIHQLTHSEERPFQCCFCQKGFKIQSKLLKHKQIHTRNKAFRALLLKKRRTE 255 +F Q++ L H+ H+ E+P++C C + F +S L +H+ IHT K ++ K + Sbjct: 475 TFSQTSSLVYHRRLHTGEKPYKCEECDEAFSFKSNLERHRIIHTGEKLYKCNECGKTFSR 534 Query: 256 SRPLPN--KLNANQGGFENGEIGESEENNPL-----DVHSIYIVPFQCPKCEKCFESEQI 308 L +L+ + ++ E G++ +H I + ++C C + F + Sbjct: 535 KSSLTRHCRLHTGEKPYQCNECGKAFRGQSALIYHQAIHGIGKL-YKCNDCHQVFSNATT 593 Query: 309 LNEH--------SCFAARSGKIPSRFKRSYNYKTIVKKILAKLKRARSKKLDNFQSEKKV 360 + H S R GK F R +Y + + + K + ++ D S Sbjct: 594 IANHWRIHNEERSYKCNRCGK----FFRHRSYLAVHWRTHSGEKPYKCEECDEAFS---- 645 Query: 361 FKKSFLRNCDLISGEQSSEQTQRTFVGSLGKHGTYKTIGNRKKKTLTLPFSWQNMGKNLK 420 FK + R+ + +GE+ + G +Y T +R+ T P+ GK Sbjct: 646 FKSNLQRHRRIHTGEKPYRCNE---CGKTFSRKSYLTC-HRRLHTGEKPYKCNECGKTFG 701 Query: 421 GILTTENILSIDNSVNKKDLSI-CGSSGEEFFNNCEVLQCGFSVPRENIRTRHKICPCDK 479 + L I +++ + C G+ F L C + T K C++ Sbjct: 702 ----RNSALIIHKAIHTGEKPYKCNECGKAFSQKSS-LTCHL-----RLHTGEKPYKCEE 751 Query: 480 CEKVFPSISKLKRHYLIHTGQRPFGCNICGKSFRQSAHLKRHEQTHNEKSPYASLCQVEF 539 C+KVF S L++H IHTG++P+ C +C K+F + +HL +H + H + PY C Sbjct: 752 CDKVFSRKSSLEKHRRIHTGEKPYKCKVCDKAFGRDSHLAQHTRIHTGEKPYK--CNECG 809 Query: 540 GNFNNLS-----------------NHSGNNVNYNASQQCQAP---GVQKYEVSESDQMSG 579 NF + S N G +N++ + G + Y+ SE ++ Sbjct: 810 KNFRHNSALVIHKAIHSGEKPYKCNECGKTFRHNSALEIHKAIHTGEKPYKCSECGKVFN 869 Query: 580 VKAESQDFIPGSTGQP---CLPNVLLESEQSNPFCSYSEHQEKNDVFLYRCSVCAKSFRS 636 KA TG+ C + ++Q++ C + H + Y+C+ C K+FR Sbjct: 870 RKANLSRHHRLHTGEKPYKCNKCGKVFNQQAHLACHHRIHTGEKP---YKCNECGKTFRH 926 Query: 637 PSKLERHYLIHAGQKPFECSVCGKTFRQAPHWKRHQLTH 675 S L H IH G+KP++C+ CGK F + RH H Sbjct: 927 NSVLVIHKTIHTGEKPYKCNECGKVFNRKAKLARHHRIH 965 Score = 214 bits (545), Expect = 2e-55 Identities = 178/698 (25%), Positives = 290/698 (41%), Gaps = 90/698 (12%) Query: 23 RNRPYVCNICFKHFETPSKLARHYLIHTGQKPFECDVCHKTFRQLVHLERHQLTHS--LP 80 R + + CN K F S L +H +IH G K ++CDVC K F Q +L H+ H+ P Sbjct: 211 REKSFQCNESGKAFNYSSVLRKHQIIHLGAKQYKCDVCGKVFNQKRYLACHRRCHTGKKP 270 Query: 81 FKCSICQRHFKNLKTFVKHQQLHNETYQNNVKQVRRLLEAKQEKSMYGVYNTFTTEERWA 140 +KC+ C + F T H +LH + + ++ +T E+ + Sbjct: 271 YKCNDCGKTFSQELTLTCHHRLHTGEKHYKCSECGKTFSRNSALVIHKAIHT--GEKSYK 328 Query: 141 LHPCSK--SDPMYSMKRRK-----NIHACTICGKMFPSQSKLDRHVLIHTGQRPFKCVLC 193 + C K S Y + R+ + C C K F +S L+RH IHTG++P+KC C Sbjct: 329 CNECGKTFSQTSYLVYHRRLHTGEKPYKCEECDKAFSFKSNLERHRKIHTGEKPYKCNEC 388 Query: 194 TKSFRQSTHLKIHQLTHSEERPFQCCFCQKGFKIQSKLLKHKQIHTRNKAFRALLLKKRR 253 +++F + + L H+ H+ E+P++C C K F S L+ H+++HT K ++ Sbjct: 389 SRTFSRKSSLTRHRRLHTGEKPYKCNDCGKTFSQMSSLVYHRRLHTGEKPYKC------- 441 Query: 254 TESRPLPNKLNANQGGFENGEIGESEENNPLDVHSIYIVPFQCPKCEKCFESEQILNEHS 313 E +N GE P++C C K F L H Sbjct: 442 -EECDEAFSFKSNLERHRRIHTGEK--------------PYKCNDCGKTFSQTSSLVYHR 486 Query: 314 CFAARSGKIPSRFKR---SYNYKTIVKKILAKLKRAR----SKKLDNFQSEKKVF--KKS 364 +G+ P + + ++++K+ L+R R +KL K F K S Sbjct: 487 --RLHTGEKPYKCEECDEAFSFKS-------NLERHRIIHTGEKLYKCNECGKTFSRKSS 537 Query: 365 FLRNCDLISGEQSSEQTQ--RTFVG--SLGKHGTYKTIGNRKKKTLTLPFSWQNMGKNLK 420 R+C L +GE+ + + + F G +L H IG K + + Sbjct: 538 LTRHCRLHTGEKPYQCNECGKAFRGQSALIYHQAIHGIGKLYK--------CNDCHQVFS 589 Query: 421 GILTTENILSIDNSVNKKDLSICGSSGEEFFNNCEVLQCGFSVPRENIRTRHKICPCDKC 480 T N I N + CG +FF + L + + K C++C Sbjct: 590 NATTIANHWRIHNEERSYKCNRCG----KFFRHRSYLAVHWRT-----HSGEKPYKCEEC 640 Query: 481 EKVFPSISKLKRHYLIHTGQRPFGCNICGKSFRQSAHLKRHEQTHNEKSPY-ASLCQVEF 539 ++ F S L+RH IHTG++P+ CN CGK+F + ++L H + H + PY + C F Sbjct: 641 DEAFSFKSNLQRHRRIHTGEKPYRCNECGKTFSRKSYLTCHRRLHTGEKPYKCNECGKTF 700 Query: 540 GNFNNL--------------SNHSGNNVNYNASQQCQA---PGVQKYEVSESDQMSGVKA 582 G + L N G + +S C G + Y+ E D++ K+ Sbjct: 701 GRNSALIIHKAIHTGEKPYKCNECGKAFSQKSSLTCHLRLHTGEKPYKCEECDKVFSRKS 760 Query: 583 ESQDFIPGSTGQPCLPNVLLESEQSNPFCSYSEHQEKNDVFLYRCSVCAKSFRSPSKLER 642 + TG+ + + + Y+C+ C K+FR S L Sbjct: 761 SLEKHRRIHTGEKPYKCKVCDKAFGRDSHLAQHTRIHTGEKPYKCNECGKNFRHNSALVI 820 Query: 643 HYLIHAGQKPFECSVCGKTFRQAPHWKRHQLTHFKERP 680 H IH+G+KP++C+ CGKTFR + H+ H E+P Sbjct: 821 HKAIHSGEKPYKCNECGKTFRHNSALEIHKAIHTGEKP 858 Score = 179 bits (454), Expect = 8e-45 Identities = 140/514 (27%), Positives = 212/514 (41%), Gaps = 80/514 (15%) Query: 27 YVCNICFKHFETPSKLARHYLIHTGQKPFECDVCHKTFRQLVHLERHQLTHSLP--FKCS 84 Y CN C K F S L RH +HTG+KP++C+ C K FR L HQ H + +KC+ Sbjct: 523 YKCNECGKTFSRKSSLTRHCRLHTGEKPYQCNECGKAFRGQSALIYHQAIHGIGKLYKCN 582 Query: 85 ICQRHFKNLKTFVKHQQLHNETYQNNVKQVRRLLEAKQEKSMYGVYNTFTTEERWALHPC 144 C + F N T H ++HNE + + + +++ W H Sbjct: 583 DCHQVFSNATTIANHWRIHNEERSYKCNRCGKFFRHRSYLAVH-----------WRTHSG 631 Query: 145 SKSDPMYSMKRRKNIHACTICGKMFPSQSKLDRHVLIHTGQRPFKCVLCTKSFRQSTHLK 204 K + C C + F +S L RH IHTG++P++C C K+F + ++L Sbjct: 632 EKP------------YKCEECDEAFSFKSNLQRHRRIHTGEKPYRCNECGKTFSRKSYLT 679 Query: 205 IHQLTHSEERPFQCCFCQKGFKIQSKLLKHKQIHTRNKAFRALLLKKRRTESRPLPNKLN 264 H+ H+ E+P++C C K F S L+ HK IHT K ++ K ++ L L Sbjct: 680 CHRRLHTGEKPYKCNECGKTFGRNSALIIHKAIHTGEKPYKCNECGKAFSQKSSLTCHLR 739 Query: 265 ANQGGFENGEIGESEENNPLDVHSIYIVPFQCPKCEKCFESEQILNEHSCFAARSGKIPS 324 + G P++C +C+K F + L +H +G+ P Sbjct: 740 LHTGE----------------------KPYKCEECDKVFSRKSSLEKHR--RIHTGEKP- 774 Query: 325 RFKRSYNYKTIVKKILAKLKRARSKKLDNFQSEKKVFK--KSFLRNCDLI------SGEQ 376 Y K K A+ ++ + K + K+F N L+ SGE+ Sbjct: 775 -----YKCKVCDKAFGRDSHLAQHTRIHTGEKPYKCNECGKNFRHNSALVIHKAIHSGEK 829 Query: 377 SSEQTQRTFVGSLGKHGTYKTIGNRKKKTLTLPFSWQNMGK--NLKGILTTENILSIDNS 434 + + G +H + I ++ T P+ GK N K L+ + L Sbjct: 830 PYKCNE---CGKTFRHNSALEI-HKAIHTGEKPYKCSECGKVFNRKANLSRHHRLHTGEK 885 Query: 435 VNKKDLSICGSSGEEFFNNCEVLQCGFSVPRENIRTRHKICPCDKCEKVFPSISKLKRHY 494 K C G+ FN L C I T K C++C K F S L H Sbjct: 886 PYK-----CNKCGK-VFNQQAHLAC-----HHRIHTGEKPYKCNECGKTFRHNSVLVIHK 934 Query: 495 LIHTGQRPFGCNICGKSFRQSAHLKRHEQTHNEK 528 IHTG++P+ CN CGK F + A L RH + H K Sbjct: 935 TIHTGEKPYKCNECGKVFNRKAKLARHHRIHTGK 968 Score = 141 bits (355), Expect = 2e-33 Identities = 76/230 (33%), Positives = 122/230 (53%), Gaps = 17/230 (7%) Query: 25 RPYVCNICFKHFETPSKLARHYLIHTGQKPFECDVCHKTFRQLVHLERHQLTHS--LPFK 82 +PY C C K F S L +H IHTG+KP++C VC K F + HL +H H+ P+K Sbjct: 745 KPYKCEECDKVFSRKSSLEKHRRIHTGEKPYKCKVCDKAFGRDSHLAQHTRIHTGEKPYK 804 Query: 83 CSICQRHFKNLKTFVKHQQLHNETYQNNVKQVRRLLEAKQEKSMYGVYNTFTTEERWALH 142 C+ C ++F++ V H+ +H+ + + + S ++ T E+ + Sbjct: 805 CNECGKNFRHNSALVIHKAIHSGEKPYKCNECGKTF---RHNSALEIHKAIHTGEK--PY 859 Query: 143 PCSKSDPMYSMK----RRKNIHA------CTICGKMFPSQSKLDRHVLIHTGQRPFKCVL 192 CS+ +++ K R +H C CGK+F Q+ L H IHTG++P+KC Sbjct: 860 KCSECGKVFNRKANLSRHHRLHTGEKPYKCNKCGKVFNQQAHLACHHRIHTGEKPYKCNE 919 Query: 193 CTKSFRQSTHLKIHQLTHSEERPFQCCFCQKGFKIQSKLLKHKQIHTRNK 242 C K+FR ++ L IH+ H+ E+P++C C K F ++KL +H +IHT K Sbjct: 920 CGKTFRHNSVLVIHKTIHTGEKPYKCNECGKVFNRKAKLARHHRIHTGKK 969 Score = 132 bits (331), Expect = 1e-30 Identities = 139/580 (23%), Positives = 229/580 (39%), Gaps = 71/580 (12%) Query: 156 RKNIHACTICGKMFPSQSKLDRHVLIHTGQRPFKCVLCTKSFRQSTHLKIHQLTHSEERP 215 R H G F + S L + +H ++ F+C K+F S+ L+ HQ+ H + Sbjct: 183 RPKTHISKNYGNNFLNSSLLTQKQEVHMREKSFQCNESGKAFNYSSVLRKHQIIHLGAKQ 242 Query: 216 FQCCFCQKGFKIQSKLLKHKQIHTRNKAFRALLLKKRRTESRPLP--NKLNANQGGFENG 273 ++C C K F + L H++ HT K ++ K ++ L ++L+ + ++ Sbjct: 243 YKCDVCGKVFNQKRYLACHRRCHTGKKPYKCNDCGKTFSQELTLTCHHRLHTGEKHYKCS 302 Query: 274 EIGES-EENNPLDVHSIYIV---PFQCPKCEKCFESEQILNEHSCFAARSGKIPSRFK-- 327 E G++ N+ L +H ++C +C K F L H +G+ P + + Sbjct: 303 ECGKTFSRNSALVIHKAIHTGEKSYKCNECGKTFSQTSYLVYHR--RLHTGEKPYKCEEC 360 Query: 328 -RSYNYKTIVKKILAKLKRARSKKLDNFQSEKKVFKKSFLRNCDLISGEQ--SSEQTQRT 384 +++++K+ +++ K+ N S K S R+ L +GE+ +T Sbjct: 361 DKAFSFKSNLER-HRKIHTGEKPYKCNECSRTFSRKSSLTRHRRLHTGEKPYKCNDCGKT 419 Query: 385 F--VGSLGKHGTYKTIGNRKKKTLTLPFSWQNMGKNLKGILTTENILSIDNSVNKKDLSI 442 F + SL H R+ T P+ + + E I + Sbjct: 420 FSQMSSLVYH--------RRLHTGEKPYKCEECDEAFSFKSNLERHRRIHTGEKPYKCND 471 Query: 443 CGS---------------SGEEFFNNCEVLQCGFSVP-----RENIRTRHKICPCDKCEK 482 CG +GE+ + CE FS I T K+ C++C K Sbjct: 472 CGKTFSQTSSLVYHRRLHTGEKPY-KCEECDEAFSFKSNLERHRIIHTGEKLYKCNECGK 530 Query: 483 VFPSISKLKRHYLIHTGQRPFGCNICGKSFRQSAHLKRHEQTHNEKSPY-ASLCQVEFGN 541 F S L RH +HTG++P+ CN CGK+FR + L H+ H Y + C F N Sbjct: 531 TFSRKSSLTRHCRLHTGEKPYQCNECGKAFRGQSALIYHQAIHGIGKLYKCNDCHQVFSN 590 Query: 542 FNNLSNHSGNNVNYNASQQCQA------------------PGVQKYEVSESDQMSGVKAE 583 ++NH + N S +C G + Y+ E D+ K+ Sbjct: 591 ATTIANHWRIH-NEERSYKCNRCGKFFRHRSYLAVHWRTHSGEKPYKCEECDEAFSFKSN 649 Query: 584 SQDFIPGSTGQP---CLPNVLLESEQSNPFCSYSEHQEKNDVFLYRCSVCAKSFRSPSKL 640 Q TG+ C S +S C H + Y+C+ C K+F S L Sbjct: 650 LQRHRRIHTGEKPYRCNECGKTFSRKSYLTCHRRLHTGEKP---YKCNECGKTFGRNSAL 706 Query: 641 ERHYLIHAGQKPFECSVCGKTFRQAPHWKRHQLTHFKERP 680 H IH G+KP++C+ CGK F Q H H E+P Sbjct: 707 IIHKAIHTGEKPYKCNECGKAFSQKSSLTCHLRLHTGEKP 746 >gi|172072608 zinc finger protein 624 [Homo sapiens] Length = 865 Score = 222 bits (566), Expect = 8e-58 Identities = 179/675 (26%), Positives = 292/675 (43%), Gaps = 104/675 (15%) Query: 23 RNRPYVCNICFKHFETPSKLARHYLIHTGQKPFECDVCHKTFRQLVHLERHQLTHS--LP 80 + +PY C+ C K F S L +H HT +KP+EC+ C KTF Q +L +H+ H+ P Sbjct: 272 KEKPYKCSTCEKAFHYRSLLIQHQRTHTKEKPYECNECGKTFSQPSYLSQHKKIHTGEKP 331 Query: 81 FKCSICQRHFKNLKTFVKHQQLH--NETYQNNVKQVRRLLEAKQEKSMYGVYNTFTTEER 138 +KC+ C + F + + HQ++H + YQ NV Sbjct: 332 YKCNECGKAFIASSSLMVHQRIHTKEKPYQCNVCGK------------------------ 367 Query: 139 WALHPCSKSDPMYSMKRRKNIHACTICGKMFPSQSKLDRHVLIHTGQRPFKCVLCTKSFR 198 + C++ + ++ + + C+ CGK F +SKL RH H G++P+KC C K+FR Sbjct: 368 -SFSQCARLNQHQRIQTGEKPYKCSECGKAFSDKSKLARHQETHNGEKPYKCDDCGKAFR 426 Query: 199 QSTHLKIHQLTHSEERPFQCCFCQKGFKIQSKLLKHKQIHTRNKAFRALLLKK--RRTES 256 ++L +HQ TH+EE+P+QC C K FK + H++IHT K FR K R S Sbjct: 427 NKSYLSVHQKTHTEEKPYQCNECGKSFKNTTIFNVHQRIHTGEKPFRCNECGKAYRSNSS 486 Query: 257 RPLPNKLNANQGGFENGEIGESEEN--NPLDVHSIYI--VPFQCPKCEKCFESEQILNEH 312 + + + + +E E G++ N + I+ P++C +C K F + L H Sbjct: 487 LIVHIRTHTGEKPYECNECGKAFNRIANFTEHQRIHTGEKPYKCNECGKAFINYSCLTVH 546 Query: 313 SCFAARSGKIPSRFKRSYNYKTIVKK----ILAKLKRARSKKLDNFQSEKKVFKKSFLRN 368 +G+ P +K + K ++ I ++ L N E K + Sbjct: 547 --HRMHTGEKP--YKCTECGKAFMRSSSLIIHQRIHTEEKPYLCNECGESFRIKSHLTVH 602 Query: 369 CDLISGEQSSEQT--QRTF--VGSLGKHGTYKTIGNRKKKTLTLPFSWQNMGKNLKGILT 424 + +GE+ + T +R F + +L +H +K T P+ + GK+ + Sbjct: 603 QRIHTGEKPYKCTDCERAFTKMVNLKEH--------QKIHTGVKPYKCYDCGKSFR---- 650 Query: 425 TENILSIDNSVNKKDLSICGSSGEEFFNNCEVLQCGFSVPRENIRTRHKICPCDKCEKVF 484 T++ L + + + + E+ F N L + T K C++C KVF Sbjct: 651 TKSYLIVHQRTHTGEKPYKCNECEKAFTNTSQL-----TVHQRRHTGEKPYKCNECGKVF 705 Query: 485 PSISKLKRHYLIHTGQRPFGCNICGKSFRQSAHLKRHEQTHNEKSPY-ASLCQVEFGNFN 543 S S H HTG++PF CN CGK+F Q H+ H++ H+ + PY +C F + Sbjct: 706 TSNSGFNTHQRTHTGEKPFKCNDCGKAFSQMVHVTEHQKIHSGEKPYKCDVCGKAFRRGS 765 Query: 544 NLSNHSGNNVNYNASQQCQAPGVQKYEVSESDQMSGVKAESQDFIPGSTGQPCLPNVLLE 603 L+ H + G + Y E G+ C+ L Sbjct: 766 YLTVHWRTHT-----------GEKPYTCKE------------------CGKGCITLSQLT 796 Query: 604 SEQSNPFCSYSEHQEKNDVFLYRCSVCAKSFRSPSKLERHYLIHAGQKPFECSVCGKTFR 663 Q H + Y+C C K+FR+ S H +H G+KP++C+ CGK FR Sbjct: 797 LHQ-------RIHTGERP---YKCEECGKAFRTNSDFTVHLRMHTGEKPYKCNECGKAFR 846 Query: 664 QAPHWKRHQLTHFKE 678 + HQ H +E Sbjct: 847 SSSSLTVHQRIHQRE 861 Score = 194 bits (493), Expect = 2e-49 Identities = 145/549 (26%), Positives = 229/549 (41%), Gaps = 79/549 (14%) Query: 14 QCVVANKLPR----NRPYVCNICFKHFETPSKLARHYLIHTGQKPFECDVCHKTFRQLVH 69 QC N+ R +PY C+ C K F SKLARH H G+KP++CD C K FR + Sbjct: 371 QCARLNQHQRIQTGEKPYKCSECGKAFSDKSKLARHQETHNGEKPYKCDDCGKAFRNKSY 430 Query: 70 LERHQLTHS--LPFKCSICQRHFKNLKTFVKHQQLHNETYQNNVKQVRRLLEAKQEKSMY 127 L HQ TH+ P++C+ C + FKN F HQ++H + + + S+ Sbjct: 431 LSVHQKTHTEEKPYQCNECGKSFKNTTIFNVHQRIHTGEKPFRCNECGKAY--RSNSSLI 488 Query: 128 GVYNTFTTEERWALHPCSKS-DPMYSMKRRKNIHA------CTICGKMFPSQSKLDRHVL 180 T T E+ + + C K+ + + + + IH C CGK F + S L H Sbjct: 489 VHIRTHTGEKPYECNECGKAFNRIANFTEHQRIHTGEKPYKCNECGKAFINYSCLTVHHR 548 Query: 181 IHTGQRPFKCVLCTKSFRQSTHLKIHQLTHSEERPFQCCFCQKGFKIQSKLLKHKQIHTR 240 +HTG++P+KC C K+F +S+ L IHQ H+EE+P+ C C + F+I+S L H++IHT Sbjct: 549 MHTGEKPYKCTECGKAFMRSSSLIIHQRIHTEEKPYLCNECGESFRIKSHLTVHQRIHTG 608 Query: 241 NKAFRALLLKKRRTESRPLPNKLNANQGGFENGEIGESEENNPLDVHSIYIVPFQCPKCE 300 K ++ ++ T+ L + G + P++C C Sbjct: 609 EKPYKCTDCERAFTKMVNLKEHQKIHTG----------------------VKPYKCYDCG 646 Query: 301 KCFESEQILNEHSCFAARSGKIPSRFKRSYNYKTIVKKILAKLKRARSKKLDNFQSEKKV 360 K F ++ L H +G+ P + T ++ +R +K KV Sbjct: 647 KSFRTKSYLIVHQ--RTHTGEKPYKCNECEKAFTNTSQLTVHQRRHTGEKPYKCNECGKV 704 Query: 361 FKKSFLRNCDLISGEQSSEQTQRTFVGSLGKHGTYKTIGNRKKKTLTLPFSWQNMGKNLK 420 F + QRT G PF + GK Sbjct: 705 F-----------TSNSGFNTHQRTHTGE-------------------KPFKCNDCGKAFS 734 Query: 421 GILTTENILSIDNSVNKKDLSICGSSGEEFFNNCEVLQCGFSVPRENIRTRHKICPCDKC 480 ++ I + +CG + F L + T K C +C Sbjct: 735 QMVHVTEHQKIHSGEKPYKCDVCGKA----FRRGSYLTVHW-----RTHTGEKPYTCKEC 785 Query: 481 EKVFPSISKLKRHYLIHTGQRPFGCNICGKSFRQSAHLKRHEQTHNEKSPY-ASLCQVEF 539 K ++S+L H IHTG+RP+ C CGK+FR ++ H + H + PY + C F Sbjct: 786 GKGCITLSQLTLHQRIHTGERPYKCEECGKAFRTNSDFTVHLRMHTGEKPYKCNECGKAF 845 Query: 540 GNFNNLSNH 548 + ++L+ H Sbjct: 846 RSSSSLTVH 854 Score = 181 bits (460), Expect = 2e-45 Identities = 149/581 (25%), Positives = 248/581 (42%), Gaps = 41/581 (7%) Query: 111 VKQVRRLLEAKQEKSMYGVYNTFTTEERWALHPCSKSDPMYSMKRRKNIHACTICGKMFP 170 ++Q L K+ + Y T E+ A H S ++ + C CGK F Sbjct: 257 IRQTSELTLGKKSNNKEKPYKCSTCEK--AFHYRSLLIQHQRTHTKEKPYECNECGKTFS 314 Query: 171 SQSKLDRHVLIHTGQRPFKCVLCTKSFRQSTHLKIHQLTHSEERPFQCCFCQKGFKIQSK 230 S L +H IHTG++P+KC C K+F S+ L +HQ H++E+P+QC C K F ++ Sbjct: 315 QPSYLSQHKKIHTGEKPYKCNECGKAFIASSSLMVHQRIHTKEKPYQCNVCGKSFSQCAR 374 Query: 231 LLKHKQIHTRNKAFRALLLKKRRTESRPLPNKLNANQGG--FENGEIGESEENNP-LDVH 287 L +H++I T K ++ K ++ L + G ++ + G++ N L VH Sbjct: 375 LNQHQRIQTGEKPYKCSECGKAFSDKSKLARHQETHNGEKPYKCDDCGKAFRNKSYLSVH 434 Query: 288 SIYIV---PFQCPKCEKCFESEQILNEHSCFAARSGKIPSRFKRSYNYKTIVKKILAKLK 344 P+QC +C K F++ I N H +G+ P R ++ ++ Sbjct: 435 QKTHTEEKPYQCNECGKSFKNTTIFNVHQ--RIHTGEKPFRCNECGKAYRSNSSLIVHIR 492 Query: 345 RARSKKLDNFQSEKKVFKK--SFLRNCDLISGEQSSEQTQRTFVGSLGKHGTYKTIGNRK 402 +K K F + +F + + +GE+ + + G + + T+ +R Sbjct: 493 THTGEKPYECNECGKAFNRIANFTEHQRIHTGEKPYKCNE---CGKAFINYSCLTVHHRM 549 Query: 403 KKTLTLPFSWQNMGKNLKGILTTENILSIDNSVNKKDLSICGSSGEEFFNNCEVLQCGFS 462 T P+ GK + + +++ ++ +C GE F + Sbjct: 550 H-TGEKPYKCTECGK---AFMRSSSLIIHQRIHTEEKPYLCNECGESFRIKSHL------ 599 Query: 463 VPRENIRTRHKICPCDKCEKVFPSISKLKRHYLIHTGQRPFGCNICGKSFRQSAHLKRHE 522 + I T K C CE+ F + LK H IHTG +P+ C CGKSFR ++L H+ Sbjct: 600 TVHQRIHTGEKPYKCTDCERAFTKMVNLKEHQKIHTGVKPYKCYDCGKSFRTKSYLIVHQ 659 Query: 523 QTHNEKSPY-ASLCQVEFGNFNNLSNHSGNNVNYNASQQCQAPGVQKYEVSESDQMSGVK 581 +TH + PY + C+ F N + L+ H Q + G + Y+ +E ++ Sbjct: 660 RTHTGEKPYKCNECEKAFTNTSQLTVH-----------QRRHTGEKPYKCNECGKVFTSN 708 Query: 582 AESQDFIPGSTGQ-PCLPNVLLESEQSNPFCSYSEHQE-KNDVFLYRCSVCAKSFRSPSK 639 + TG+ P N + + +EHQ+ + Y+C VC K+FR S Sbjct: 709 SGFNTHQRTHTGEKPFKCNDC--GKAFSQMVHVTEHQKIHSGEKPYKCDVCGKAFRRGSY 766 Query: 640 LERHYLIHAGQKPFECSVCGKTFRQAPHWKRHQLTHFKERP 680 L H+ H G+KP+ C CGK HQ H ERP Sbjct: 767 LTVHWRTHTGEKPYTCKECGKGCITLSQLTLHQRIHTGERP 807 Score = 106 bits (265), Expect = 6e-23 Identities = 84/342 (24%), Positives = 151/342 (44%), Gaps = 37/342 (10%) Query: 363 KSFLRNCDLISGEQSSEQTQRTFVGSLGKHGTYKT--IGNRKKKTLTLPFSWQNMGKNLK 420 K+ + +L G++S+ + + + K Y++ I +++ T P+ GK Sbjct: 255 KAIRQTSELTLGKKSNNKEKPYKCSTCEKAFHYRSLLIQHQRTHTKEKPYECNECGKTF- 313 Query: 421 GILTTENILSIDNSVNKKDLSI-CGSSGEEFFNNCEVLQCGFSVPRENIRTRHKICPCDK 479 + + LS ++ + C G+ F + ++ + I T+ K C+ Sbjct: 314 ---SQPSYLSQHKKIHTGEKPYKCNECGKAFIASSSLMV------HQRIHTKEKPYQCNV 364 Query: 480 CEKVFPSISKLKRHYLIHTGQRPFGCNICGKSFRQSAHLKRHEQTHNEKSPY-ASLCQVE 538 C K F ++L +H I TG++P+ C+ CGK+F + L RH++THN + PY C Sbjct: 365 CGKSFSQCARLNQHQRIQTGEKPYKCSECGKAFSDKSKLARHQETHNGEKPYKCDDCGKA 424 Query: 539 FGNFNNLSNHS------------------GNNVNYNASQQCQAPGVQKYEVSESDQMSGV 580 F N + LS H N +N Q+ G + + +E + Sbjct: 425 FRNKSYLSVHQKTHTEEKPYQCNECGKSFKNTTIFNVHQRIHT-GEKPFRCNECGKAYRS 483 Query: 581 KAESQDFIPGSTGQPCLPNVLLESEQS-NPFCSYSEHQE-KNDVFLYRCSVCAKSFRSPS 638 + I TG+ P E ++ N +++EHQ Y+C+ C K+F + S Sbjct: 484 NSSLIVHIRTHTGEK--PYECNECGKAFNRIANFTEHQRIHTGEKPYKCNECGKAFINYS 541 Query: 639 KLERHYLIHAGQKPFECSVCGKTFRQAPHWKRHQLTHFKERP 680 L H+ +H G+KP++C+ CGK F ++ HQ H +E+P Sbjct: 542 CLTVHHRMHTGEKPYKCTECGKAFMRSSSLIIHQRIHTEEKP 583 Score = 68.2 bits (165), Expect = 2e-11 Identities = 33/88 (37%), Positives = 48/88 (54%), Gaps = 6/88 (6%) Query: 25 RPYVCNICFKHFETPSKLARHYLIHTGQKPFECDVCHKTFRQ----LVHLERHQLTHSLP 80 +PY C C K T S+L H IHTG++P++C+ C K FR VHL H T P Sbjct: 778 KPYTCKECGKGCITLSQLTLHQRIHTGERPYKCEECGKAFRTNSDFTVHLRMH--TGEKP 835 Query: 81 FKCSICQRHFKNLKTFVKHQQLHNETYQ 108 +KC+ C + F++ + HQ++H Q Sbjct: 836 YKCNECGKAFRSSSSLTVHQRIHQRETQ 863 >gi|156627573 zinc finger protein 836 [Homo sapiens] Length = 936 Score = 222 bits (565), Expect = 1e-57 Identities = 184/699 (26%), Positives = 284/699 (40%), Gaps = 92/699 (13%) Query: 23 RNRPYVCNICFKHFETPSKLARHYLIHTGQKPFECDVCHKTFRQLVHLERHQLTHSL--P 80 R +PY+C C K F S L H ++HT +KP++C+ C K F + L HQ+ H+ P Sbjct: 214 REKPYMCKGCGKAFRVSSSLINHQMVHTTEKPYKCNECGKAFHRGSLLTIHQIVHTRGKP 273 Query: 81 FKCSICQRHFKNLKTFVKHQQLHNETYQNNVKQVRRLLEAKQEKSMYGVYNTFTTEERWA 140 ++C +C + F+ V H++ H + + +++ T E+ + Sbjct: 274 YQCGVCGKIFRQNSDLVNHRRSHTGEKPYKCNECGKSFSQSYNLAIH--QRIHTGEKPYK 331 Query: 141 LHPCSKSDPMYSMKRRKNI-------HACTICGKMFPSQSKLDRHVLIHTGQRPFKCVLC 193 + C K+ S I + C ICGK+F S L H IHTG++P+KC +C Sbjct: 332 CNECGKTFKQGSCLTTHQIIHTGEKPYQCDICGKVFRQNSNLVNHQRIHTGEKPYKCNIC 391 Query: 194 TKSFRQSTHLKIHQLTHSEERPFQCCFCQKGFKIQSKLLKHKQIHTRNKAFRALLLKKRR 253 KSF QS++L HQ HS +P++C C K FK S L H+ IHT K + + K Sbjct: 392 GKSFSQSSNLATHQTVHSGNKPYKCDECGKTFKRSSSLTTHQIIHTGEKPYTCDVCDKVF 451 Query: 254 TESRPLPNKLNANQGG--FENGEIGE--SEENNPLDVHSIYI--VPFQCPKCEKCFESEQ 307 ++ L ++ G ++ E G+ S+ ++ + I+ P++C KC K F+ Sbjct: 452 SQRSQLARHQRSHTGEKPYKCNECGKVFSQTSHLVGHRRIHTGEKPYKCDKCGKAFKQGS 511 Query: 308 ILNEHSCFAARSGKIPSRFKRSYNYKTIVKKILAKLKRARSKKLDNFQSEKKVFKKSFL- 366 +L H K+ R K+ + K + S L Sbjct: 512 LLTRH-----------------------------KIIHTREKRYQCGECGKVFSENSCLV 542 Query: 367 RNCDLISGEQ--SSEQTQRTFVGSLGKHGTYKTIGNRKKKTLTLPFSWQNMGKNLKGILT 424 R+ + +GEQ + F S G +K I +K PF G + Sbjct: 543 RHLRIHTGEQPYKCNVCGKVFNYS-GNLSIHKRIHTGEK-----PFQCNECGTVFRNYSC 596 Query: 425 TENILSIDNSVNKKDLSICGS---------------SGEEFF--NNCEVLQCGFS--VPR 465 L I ++CG +GE+ F N C + +S Sbjct: 597 LARHLRIHTGQKPYKCNVCGKVFNDSGNLSNHKRIHTGEKPFQCNECGKVFSYYSCLARH 656 Query: 466 ENIRTRHKICPCDKCEKVFPSISKLKRHYLIHTGQRPFGCNICGKSFRQSAHLKR-HEQT 524 I T K C+ C K + S L +H +IHTG++P+ CN G +F QS+ L R H Sbjct: 657 RKIHTGEKPYKCNDCGKAYTQRSSLTKHLIIHTGEKPYNCNEFGGAFIQSSKLARYHRNP 716 Query: 525 HNEKSPYASLCQVEFGNFNNLSNHSGNNVNYNASQQCQAPGVQKYEVSESDQM---SGVK 581 EK S C F + L+ H Q + G Y+ E Q+ + Sbjct: 717 TGEKPHKCSHCGRTFSHITGLTYH-----------QRRHTGEMPYKCIECGQVFNSTSNL 765 Query: 582 AESQDFIPGSTGQPCLPNVLLESEQSNPFCSYSEHQEKNDVFLYRCSVCAKSFRSPSKLE 641 A + G C + QS S H + Y C+ C K+FR S L Sbjct: 766 ARHRRIHTGEKPYKCNECGKVFRHQSTLARHRSIHTGEKP---YVCNECGKAFRVRSILV 822 Query: 642 RHYLIHAGQKPFECSVCGKTFRQAPHWKRHQLTHFKERP 680 H +H G KP++C+ CGK F + HQ H E+P Sbjct: 823 NHQKMHTGDKPYKCNECGKAFIERSKLVYHQRNHTGEKP 861 Score = 217 bits (552), Expect = 3e-56 Identities = 184/678 (27%), Positives = 286/678 (42%), Gaps = 114/678 (16%) Query: 25 RPYVCNICFKHFETPSKLARHYLIHTGQKPFECDVCHKTFRQLVHLERHQLTHS--LPFK 82 +PY CN C K F+ S L H +IHTG+KP++CD+C K FRQ +L HQ H+ P+K Sbjct: 328 KPYKCNECGKTFKQGSCLTTHQIIHTGEKPYQCDICGKVFRQNSNLVNHQRIHTGEKPYK 387 Query: 83 CSICQRHFKNLKTFVKHQQLHNETYQNNVKQVRRLLEAKQEKSMYGVYNTFTTEERWALH 142 C+IC + F HQ +H+ + + + + + + +T Sbjct: 388 CNICGKSFSQSSNLATHQTVHSGNKPYKCDECGKTFKRSSSLTTHQIIHT---------- 437 Query: 143 PCSKSDPMYSMKRRKNIHACTICGKMFPSQSKLDRHVLIHTGQRPFKCVLCTKSFRQSTH 202 + + C +C K+F +S+L RH HTG++P+KC C K F Q++H Sbjct: 438 -------------GEKPYTCDVCDKVFSQRSQLARHQRSHTGEKPYKCNECGKVFSQTSH 484 Query: 203 LKIHQLTHSEERPFQCCFCQKGFKIQSKLLKHKQIHTRNKAFRALLLKKRRTESRPLPNK 262 L H+ H+ E+P++C C K FK S L +HK IHTR K ++ K +E+ L Sbjct: 485 LVGHRRIHTGEKPYKCDKCGKAFKQGSLLTRHKIIHTREKRYQCGECGKVFSENSCLVRH 544 Query: 263 LNANQGG--FENGEIGES-EENNPLDVHSIYIV---PFQCPKCEKCFESEQILNEHSCFA 316 L + G ++ G+ + L +H PFQC +C F + +SC Sbjct: 545 LRIHTGEQPYKCNVCGKVFNYSGNLSIHKRIHTGEKPFQCNECGTVFRN------YSCL- 597 Query: 317 ARSGKIPSRFKRSYNYKTIVKKILAKLKRARSKKLDN----FQSEK--KVFK--KSFLRN 368 AR +I + ++ Y K + K++ FQ + KVF R+ Sbjct: 598 ARHLRIHTG-QKPYKCNVCGKVFNDSGNLSNHKRIHTGEKPFQCNECGKVFSYYSCLARH 656 Query: 369 CDLISGEQ-------SSEQTQRTFVGSLGKHGTYKTIGNRKKKTLTLPFSWQNMGKNLKG 421 + +GE+ TQR+ SL KH T G + P++ G Sbjct: 657 RKIHTGEKPYKCNDCGKAYTQRS---SLTKHLIIHT-GEK-------PYNCNEFGG---A 702 Query: 422 ILTTENILSIDNSVNKKDLSICGSSGEEFFNNCEVLQCGFSVPRENIRTRHKICPCDKCE 481 + + + + + C G F + + + R +K C +C Sbjct: 703 FIQSSKLARYHRNPTGEKPHKCSHCGRTFSH---ITGLTYHQRRHTGEMPYK---CIECG 756 Query: 482 KVFPSISKLKRHYLIHTGQRPFGCNICGKSFRQSAHLKRHEQTHNEKSPYA-SLCQVEFG 540 +VF S S L RH IHTG++P+ CN CGK FR + L RH H + PY + C F Sbjct: 757 QVFNSTSNLARHRRIHTGEKPYKCNECGKVFRHQSTLARHRSIHTGEKPYVCNECGKAFR 816 Query: 541 NFNNLSNHSGNNVNYNASQQCQAPGVQKYEVSESDQMSGVKAESQDFIPGSTGQPCLPNV 600 + L NH Q G + Y+ +E G+ + Sbjct: 817 VRSILVNH-----------QKMHTGDKPYKCNEC------------------GKAFIERS 847 Query: 601 LLESEQSNPFCSYSEHQEKNDVFLYRCSVCAKSFRSPSKLERHYLIHAGQKPFECSVCGK 660 L Q N H + Y+C C K+F S L +H +IH+G+KP++C+ CGK Sbjct: 848 KLVYHQRN-------HTGEKP---YKCIECGKAFGRFSCLNKHQMIHSGEKPYKCNECGK 897 Query: 661 TFRQAPHWKRHQLTHFKE 678 +F +HQ H E Sbjct: 898 SFISRSGLTKHQTKHTAE 915 Score = 203 bits (517), Expect = 4e-52 Identities = 169/680 (24%), Positives = 271/680 (39%), Gaps = 105/680 (15%) Query: 33 FKHFETPSKLARHYLIHTGQKPFECDVCHKTFRQLVHLERHQLTHSL--PFKCSICQRHF 90 F P++L + H +KP+ C C K FR L HQ+ H+ P+KC+ C + F Sbjct: 199 FLQLSLPTQLEK---THIREKPYMCKGCGKAFRVSSSLINHQMVHTTEKPYKCNECGKAF 255 Query: 91 KNLKTFVKHQQLHNETYQNNVKQVRRLLEAKQEKSMYGVYNTFTTEERWALHPCSKS-DP 149 HQ +H ++ +Q + + T E+ + + C KS Sbjct: 256 HRGSLLTIHQIVHTRGKPYQCGVCGKIF--RQNSDLVNHRRSHTGEKPYKCNECGKSFSQ 313 Query: 150 MYSMKRRKNIHA------CTICGKMFPSQSKLDRHVLIHTGQRPFKCVLCTKSFRQSTHL 203 Y++ + IH C CGK F S L H +IHTG++P++C +C K FRQ+++L Sbjct: 314 SYNLAIHQRIHTGEKPYKCNECGKTFKQGSCLTTHQIIHTGEKPYQCDICGKVFRQNSNL 373 Query: 204 KIHQLTHSEERPFQCCFCQKGFKIQSKLLKHKQIHTRNKAFRALLLKKRRTESRPLPNKL 263 HQ H+ E+P++C C K F S L H+ +H+ NK ++ Sbjct: 374 VNHQRIHTGEKPYKCNICGKSFSQSSNLATHQTVHSGNKPYKC----------------- 416 Query: 264 NANQGGFENGEIGES-EENNPLDVHSIYIV---PFQCPKCEKCFESEQILNEHSCFAARS 319 E G++ + ++ L H I P+ C C+K F L H + + Sbjct: 417 ---------DECGKTFKRSSSLTTHQIIHTGEKPYTCDVCDKVFSQRSQLARHQ--RSHT 465 Query: 320 GKIPSRFKRSYNYKTIVKKILAKLKRARSKKLDNFQSEKKVFKKSFLRNCDLISGEQSSE 379 G+ P + + ++ + +K K FK+ L Sbjct: 466 GEKPYKCNECGKVFSQTSHLVGHRRIHTGEKPYKCDKCGKAFKQGSL------------- 512 Query: 380 QTQRTFVGSLGKHGTYKTIGNRKKKTLTLPFSWQNMGKNLKGILTTENILSIDNSVNKKD 439 L +H K I R+K+ + GK L I Sbjct: 513 ---------LTRH---KIIHTREKR-----YQCGECGKVFSENSCLVRHLRIHTGEQPYK 555 Query: 440 LSICGSSGEEFFNNCEVLQCGFSVPRENIRTRHKICPCDKCEKVFPSISKLKRHYLIHTG 499 ++CG + FN L + I T K C++C VF + S L RH IHTG Sbjct: 556 CNVCG----KVFNYSGNLSI-----HKRIHTGEKPFQCNECGTVFRNYSCLARHLRIHTG 606 Query: 500 QRPFGCNICGKSFRQSAHLKRHEQTHNEKSPY-ASLCQVEFGNFNNLSNHSGNNVNYNAS 558 Q+P+ CN+CGK F S +L H++ H + P+ + C F ++ L+ H + Sbjct: 607 QKPYKCNVCGKVFNDSGNLSNHKRIHTGEKPFQCNECGKVFSYYSCLARHRKIHTG-EKP 665 Query: 559 QQCQAPGVQKYEVSESDQMSGVKAESQDFIPGSTGQPCLPNVLLESEQSNPF------CS 612 +C G + S + + + + G + + L NP CS Sbjct: 666 YKCNDCGKAYTQRSSLTKHLIIHTGEKPYNCNEFGGAFIQSSKLARYHRNPTGEKPHKCS 725 Query: 613 Y-----------SEHQEKNDVFL-YRCSVCAKSFRSPSKLERHYLIHAGQKPFECSVCGK 660 + + HQ ++ + Y+C C + F S S L RH IH G+KP++C+ CGK Sbjct: 726 HCGRTFSHITGLTYHQRRHTGEMPYKCIECGQVFNSTSNLARHRRIHTGEKPYKCNECGK 785 Query: 661 TFRQAPHWKRHQLTHFKERP 680 FR RH+ H E+P Sbjct: 786 VFRHQSTLARHRSIHTGEKP 805 Score = 194 bits (492), Expect = 3e-49 Identities = 151/553 (27%), Positives = 231/553 (41%), Gaps = 68/553 (12%) Query: 25 RPYVCNICFKHFETPSKLARHYLIHTGQKPFECDVCHKTFRQLVHLERHQLTHS--LPFK 82 +PY CNIC K F S LA H +H+G KP++CD C KTF++ L HQ+ H+ P+ Sbjct: 384 KPYKCNICGKSFSQSSNLATHQTVHSGNKPYKCDECGKTFKRSSSLTTHQIIHTGEKPYT 443 Query: 83 CSICQRHFKNLKTFVKHQQLHNETYQNNVKQVRRLLEAKQEKSMYGVYNTFTTEERWALH 142 C +C + F +HQ+ H + ++ Q + G T E+ + Sbjct: 444 CDVCDKVFSQRSQLARHQRSHTGEKPYKCNECGKVFS--QTSHLVGHRRIHTGEKPYKCD 501 Query: 143 PCSKSDPMYSM-KRRKNIHA------CTICGKMFPSQSKLDRHVLIHTGQRPFKCVLCTK 195 C K+ S+ R K IH C CGK+F S L RH+ IHTG++P+KC +C K Sbjct: 502 KCGKAFKQGSLLTRHKIIHTREKRYQCGECGKVFSENSCLVRHLRIHTGEQPYKCNVCGK 561 Query: 196 SFRQSTHLKIHQLTHSEERPFQCCFCQKGFKIQSKLLKHKQIHTRNKAFRALLLKKRRTE 255 F S +L IH+ H+ E+PFQC C F+ S L +H +IHT K ++ + K + Sbjct: 562 VFNYSGNLSIHKRIHTGEKPFQCNECGTVFRNYSCLARHLRIHTGQKPYKCNVCGKVFND 621 Query: 256 SRPLPN--KLNANQGGFENGEIGESEENNPLDVHSIYIV------------PFQCPKCEK 301 S L N +++ + F+ E G+ V S Y P++C C K Sbjct: 622 SGNLSNHKRIHTGEKPFQCNECGK--------VFSYYSCLARHRKIHTGEKPYKCNDCGK 673 Query: 302 CFESEQILNEHSCFAARSGKIPSRFKRSYNYKTIVKKILAKLKRARSKKLDNFQSEKKVF 361 + L +H +G+ P YN + K AR + N EK Sbjct: 674 AYTQRSSLTKH--LIIHTGEKP------YNCNEFGGAFIQSSKLARYHR--NPTGEKPHK 723 Query: 362 KKSFLRNCDLISG------EQSSEQTQRTFVGSLGKHGTYKTIGNRKKKTLTLPFSWQNM 415 R I+G + E + + T +R+ T P+ Sbjct: 724 CSHCGRTFSHITGLTYHQRRHTGEMPYKCIECGQVFNSTSNLARHRRIHTGEKPYKCNEC 783 Query: 416 GKNLKGILTTENILSIDNSVNKKDLSICGSS---------------GEEFF--NNC--EV 456 GK + T SI + CG + G++ + N C Sbjct: 784 GKVFRHQSTLARHRSIHTGEKPYVCNECGKAFRVRSILVNHQKMHTGDKPYKCNECGKAF 843 Query: 457 LQCGFSVPRENIRTRHKICPCDKCEKVFPSISKLKRHYLIHTGQRPFGCNICGKSFRQSA 516 ++ V + T K C +C K F S L +H +IH+G++P+ CN CGKSF + Sbjct: 844 IERSKLVYHQRNHTGEKPYKCIECGKAFGRFSCLNKHQMIHSGEKPYKCNECGKSFISRS 903 Query: 517 HLKRHEQTHNEKS 529 L +H+ H +S Sbjct: 904 GLTKHQTKHTAES 916 Score = 134 bits (337), Expect = 3e-31 Identities = 156/640 (24%), Positives = 254/640 (39%), Gaps = 98/640 (15%) Query: 66 QLVHLERHQLTHSLPFKCSICQRHFKNLKTFVKHQQLHNE----TYQNNVKQVRRLLEAK 121 Q V LERH+ F Q++ ++L+ K +++ + TY+NN+ R Sbjct: 71 QTVTLERHECYDVENFYLREIQKNLQDLEFQWKDGEINYKEVPMTYKNNLNGKRG----- 125 Query: 122 QEKSMYGVYNTFTTEERWALHPCSKSDPMYSMKRRKNIHACTICGKMFPSQSKLDRHVLI 181 + S V N E + L S+ + + I+ C S+ ++ L+ Sbjct: 126 -QHSQEDVENK-CIENQLTLSFQSRLTELQKFQTEGKIYECN------QSEKTVNNSSLV 177 Query: 182 HTGQRPFKCVLCTKSFR-QSTHLKIH-----QLTHSEERPFQCCFCQKGFKIQSKLLKHK 235 QR V S + ++ L++ + TH E+P+ C C K F++ S L+ H+ Sbjct: 178 SPLQRILPSVQTNISKKYENEFLQLSLPTQLEKTHIREKPYMCKGCGKAFRVSSSLINHQ 237 Query: 236 QIHTRNKAFRALLLKKRRTESRPLPNKLNANQGGFENGEIGESEENNPLDVHSIYIV--- 292 +HT K P K N F G + L +H I Sbjct: 238 MVHTTEK-----------------PYKCNECGKAFHRGSL--------LTIHQIVHTRGK 272 Query: 293 PFQCPKCEKCFESEQILNEHSCFAARSGKIPSR-------FKRSYNYKTIVKKILAKLKR 345 P+QC C K F L H + +G+ P + F +SYN I ++I K Sbjct: 273 PYQCGVCGKIFRQNSDLVNHR--RSHTGEKPYKCNECGKSFSQSYNL-AIHQRIHTGEKP 329 Query: 346 ARSKKLDNFQSEKKVFKK-SFLRNCDLISGEQSSEQTQRTFVGSLGKHGTYKTIGNRKKK 404 + + K FK+ S L +I + Q G + + + + +++ Sbjct: 330 YKCNECG------KTFKQGSCLTTHQII--HTGEKPYQCDICGKVFRQNS-NLVNHQRIH 380 Query: 405 TLTLPFSWQNMGKNL--KGILTTENILSIDNSVNKKDLSICGSSGEEFFNNCEVLQCGFS 462 T P+ GK+ L T + N K C G+ F + + Sbjct: 381 TGEKPYKCNICGKSFSQSSNLATHQTVHSGNKPYK-----CDECGKTFKRSSSL------ 429 Query: 463 VPRENIRTRHKICPCDKCEKVFPSISKLKRHYLIHTGQRPFGCNICGKSFRQSAHLKRHE 522 + I T K CD C+KVF S+L RH HTG++P+ CN CGK F Q++HL H Sbjct: 430 TTHQIIHTGEKPYTCDVCDKVFSQRSQLARHQRSHTGEKPYKCNECGKVFSQTSHLVGHR 489 Query: 523 QTHNEKSPY-ASLCQVEFGNFNNLSNHSGNNVNYNASQQCQAPGVQKYEVSESDQMSGVK 581 + H + PY C F + L+ H + + ++ Q K S + ++ Sbjct: 490 RIHTGEKPYKCDKCGKAFKQGSLLTRH---KIIHTREKRYQCGECGKVFSENSCLVRHLR 546 Query: 582 AESQDFIPGSTGQPCLPNVLLESEQSNPFCSYSEHQE-KNDVFLYRCSVCAKSFRSPSKL 640 + + QP NV + N + S H+ ++C+ C FR+ S L Sbjct: 547 IHTGE-------QPYKCNVC--GKVFNYSGNLSIHKRIHTGEKPFQCNECGTVFRNYSCL 597 Query: 641 ERHYLIHAGQKPFECSVCGKTFRQAPHWKRHQLTHFKERP 680 RH IH GQKP++C+VCGK F + + H+ H E+P Sbjct: 598 ARHLRIHTGQKPYKCNVCGKVFNDSGNLSNHKRIHTGEKP 637 Score = 70.9 bits (172), Expect = 4e-12 Identities = 34/82 (41%), Positives = 46/82 (56%), Gaps = 2/82 (2%) Query: 24 NRPYVCNICFKHFETPSKLARHYLIHTGQKPFECDVCHKTFRQLVHLERHQLTHS--LPF 81 ++PY CN C K F SKL H HTG+KP++C C K F + L +HQ+ HS P+ Sbjct: 831 DKPYKCNECGKAFIERSKLVYHQRNHTGEKPYKCIECGKAFGRFSCLNKHQMIHSGEKPY 890 Query: 82 KCSICQRHFKNLKTFVKHQQLH 103 KC+ C + F + KHQ H Sbjct: 891 KCNECGKSFISRSGLTKHQTKH 912 >gi|54291708 zinc finger protein 780B [Homo sapiens] Length = 833 Score = 220 bits (560), Expect = 4e-57 Identities = 186/675 (27%), Positives = 281/675 (41%), Gaps = 102/675 (15%) Query: 24 NRPYVCNICFKHFETPSKLARHYLIHTGQKPFECDVCHKTFRQLVHLERHQLTHS--LPF 81 ++PY C C K+F S L +H IHTG+KP++C C K F+ + L RHQ H+ F Sbjct: 162 HKPYECKECGKYFSCGSNLIQHQSIHTGEKPYKCKECGKAFQLHIQLTRHQKFHTGEKTF 221 Query: 82 KCSICQRHFKNLKTFVKHQQLHNETYQNNVKQVRRLLEAKQEKSMYGVYNTFTTEERWAL 141 +C C + F +H+ +H V++L E K+ Sbjct: 222 ECKECGKAFNLPTQLNRHKNIHT---------VKKLFECKE------------------- 253 Query: 142 HPCSKS-DPMYSMKRRKNIHA------CTICGKMFPSQSKLDRHVLIHTGQRPFKCVLCT 194 C KS + ++ + ++IHA C CGK F S L +H IH+ ++PF C C Sbjct: 254 --CGKSFNRSSNLTQHQSIHAGVKPYQCKECGKAFNRGSNLIQHQKIHSNEKPFVCRECE 311 Query: 195 KSFRQSTHLKIHQLTHSEERPFQCCFCQKGFKIQSKLLKHKQIHTRNKAFRALLLKKRRT 254 +FR L H H+ E+PF+C C+K F + +KL++H++IH K F K + Sbjct: 312 MAFRYHYQLIEHCRIHTGEKPFECKECRKAFTLLTKLVRHQKIHMGEKPFECRECGKAFS 371 Query: 255 ESRPLPNKLNANQG--GFENGEIGES--EENNPLDVHSIY--IVPFQCPKCEKCFESEQI 308 L N + G FE E G+S +N + SI+ + P++C +C K F Sbjct: 372 LLNQLNRHKNIHTGEKPFECKECGKSFNRSSNLIQHQSIHADVKPYECKECGKGFNRGAN 431 Query: 309 LNEHSCFAARSGKIPSRFKRSYNYKTIVKKILAKLKRARSKKLDNFQSEKKVFKKSFLRN 368 L +H KI S N K V + R + +++ Sbjct: 432 LIQHQ-------KIHS------NEKPFVCRECEMAFR---------------YHYQLIQH 463 Query: 369 CDLISGEQSSE--QTQRTFVGSLGKHGTYKTIGNRKKKTLTLPFSWQNMGKNLKGILTTE 426 C + +G + E + + F L + +K I +K PF ++ GK Sbjct: 464 CQIHTGGKPFECKECGKAF-SLLTQLARHKNIHTGEK-----PFECKDCGKAFN---RGS 514 Query: 427 NILSIDNSVNKKDLSICGSSGEEFFNNCEVLQCGFSVPRENIRTRHKICPCDKCEKVFPS 486 N++ + + C G+ F + ++ Q E T K C +C K F Sbjct: 515 NLVQHQSIHTGEKPYECKECGKAFRLHLQLSQ------HEKTHTGEKPFECKECGKFFRR 568 Query: 487 ISKLKRHYLIHTGQRPFGCNICGKSFRQSAHLKRHEQTHNEKSPY-ASLCQVEFGNFNNL 545 S L +H IHTG++PF C CGK+FR HL RH++ H + P+ C F L Sbjct: 569 GSNLNQHRSIHTGKKPFECKECGKAFRLHMHLIRHQKFHTGEKPFECKECGKAFSLHTQL 628 Query: 546 SNHSGNNVNYNASQQCQAPGVQKYEVSESDQMSGVKAESQDFIPGSTGQPCLPNVLLESE 605 NH N +C+ G VS Q + A + + G+ S Sbjct: 629 -NHHKNIHTGEKPFKCKECGKSFNRVSNLVQHQSIHAGVKPYECKECGKGF-------SR 680 Query: 606 QSNPFCSYSEHQEKNDVFLYRCSVCAKSFRSPSKLERHYLIHAGQKPFECSVCGKTFRQA 665 SN H + C C K+FR +L HY IH G+KPFEC CGK F Sbjct: 681 VSNLIQHQKTHSSAKP---FVCKECRKTFRYHYQLTEHYRIHTGEKPFECKECGKAFGLL 737 Query: 666 PHWKRHQLTHFKERP 680 +HQ+ H E+P Sbjct: 738 TQLAQHQIIHTGEKP 752 Score = 200 bits (508), Expect = 4e-51 Identities = 171/667 (25%), Positives = 278/667 (41%), Gaps = 104/667 (15%) Query: 25 RPYVCNICFKHFETPSKLARHYLIHTGQKPFECDVCHKTFRQLVHLERHQLTHS--LPFK 82 + + C C K F P++L RH IHT +K FEC C K+F + +L +HQ H+ P++ Sbjct: 219 KTFECKECGKAFNLPTQLNRHKNIHTVKKLFECKECGKSFNRSSNLTQHQSIHAGVKPYQ 278 Query: 83 CSICQRHFKNLKTFVKHQQLHNETYQNNVKQVRRLLEAKQEKSMYGVYNTFTTEERWALH 142 C C + F ++HQ++H+ ++ + + + T E+ + Sbjct: 279 CKECGKAFNRGSNLIQHQKIHSNEKPFVCRECE--MAFRYHYQLIEHCRIHTGEKPFECK 336 Query: 143 PCSKSDPMYS-MKRRKNIHA------CTICGKMFPSQSKLDRHVLIHTGQRPFKCVLCTK 195 C K+ + + + R + IH C CGK F ++L+RH IHTG++PF+C C K Sbjct: 337 ECRKAFTLLTKLVRHQKIHMGEKPFECRECGKAFSLLNQLNRHKNIHTGEKPFECKECGK 396 Query: 196 SFRQSTHLKIHQLTHSEERPFQCCFCQKGFKIQSKLLKHKQIHTRNKAFRALLLKKRRTE 255 SF +S++L HQ H++ +P++C C KGF + L++H++IH+ K F + Sbjct: 397 SFNRSSNLIQHQSIHADVKPYECKECGKGFNRGANLIQHQKIHSNEKPFVCRECEMAFRY 456 Query: 256 SRPLPNKLNANQGG--FENGEIGE-----SEENNPLDVHSIYIVPFQCPKCEKCFESEQI 308 L + GG FE E G+ ++ ++H+ PF+C C K F Sbjct: 457 HYQLIQHCQIHTGGKPFECKECGKAFSLLTQLARHKNIHT-GEKPFECKDCGKAFNRGSN 515 Query: 309 LNEHSCFAARSGKIPSRFKRSYNYKTIVKKILAKLKRARSKKLDNFQS--EKKVFKKSFL 366 L +H + +G+ P Y K K L+ ++ +K + E K K F Sbjct: 516 LVQHQ--SIHTGEKP------YECKECGKAFRLHLQLSQHEKTHTGEKPFECKECGKFFR 567 Query: 367 RNCDLISGEQSSEQTQRTFVGSLGKHGTYKTIGNRKKKTLTLPFSWQNMGKNLKGILTTE 426 R +L +++I KK PF + GK + L Sbjct: 568 RGSNL---------------------NQHRSIHTGKK-----PFECKECGKAFR--LHMH 599 Query: 427 NILSIDNSVNKKDLSICGSSGEEFFNNCEVLQCGFSVPRENIRTRHKICPCDKCEKVFPS 486 I +K C G+ F + ++ +NI T K C +C K F Sbjct: 600 LIRHQKFHTGEKPFE-CKECGKAFSLHTQLNH------HKNIHTGEKPFKCKECGKSFNR 652 Query: 487 ISKLKRHYLIHTGQRPFGCNICGKSFRQSAHLKRHEQTHNEKSPY-ASLCQVEFGNFNNL 545 +S L +H IH G +P+ C CGK F + ++L +H++TH+ P+ C+ F L Sbjct: 653 VSNLVQHQSIHAGVKPYECKECGKGFSRVSNLIQHQKTHSSAKPFVCKECRKTFRYHYQL 712 Query: 546 SNHSGNNVNYNASQQCQAPGVQKYEVSESDQMSGVKAESQDFIPGSTGQPCLPNVLLESE 605 + H + G + +E E + G+ + TG+ Sbjct: 713 TEHYRIHT-----------GEKPFECKECGKAFGLLTQLAQHQIIHTGE----------- 750 Query: 606 QSNPFCSYSEHQEKNDVFLYRCSVCAKSFRSPSKLERHYLIHAGQKPFECSVCGKTFRQA 665 PF +C C K+F S L + IH G+KP+EC CGK FR Sbjct: 751 --KPF---------------KCKECGKAFNRGSNLVQPQSIHTGEKPYECKECGKAFRLH 793 Query: 666 PHWKRHQ 672 HQ Sbjct: 794 LQLSLHQ 800 Score = 169 bits (427), Expect = 1e-41 Identities = 141/530 (26%), Positives = 222/530 (41%), Gaps = 76/530 (14%) Query: 25 RPYVCNICFKHFETPSKLARHYLIHTGQKPFECDVCHKTFRQLVHLERHQLTHS--LPFK 82 +P+ C C K F +KL RH IH G+KPFEC C K F L L RH+ H+ PF+ Sbjct: 331 KPFECKECRKAFTLLTKLVRHQKIHMGEKPFECRECGKAFSLLNQLNRHKNIHTGEKPFE 390 Query: 83 CSICQRHFKNLKTFVKHQQLHNETYQNNVKQVRRLLEAKQEKSMYGVYNTFTTEERWALH 142 C C + F ++HQ +H + K+ + + ++ + E+ + Sbjct: 391 CKECGKSFNRSSNLIQHQSIHADVKPYECKECGKGFN--RGANLIQHQKIHSNEKPFVCR 448 Query: 143 PCSKSDPM-YSMKRRKNIHA------CTICGKMFPSQSKLDRHVLIHTGQRPFKCVLCTK 195 C + Y + + IH C CGK F ++L RH IHTG++PF+C C K Sbjct: 449 ECEMAFRYHYQLIQHCQIHTGGKPFECKECGKAFSLLTQLARHKNIHTGEKPFECKDCGK 508 Query: 196 SFRQSTHLKIHQLTHSEERPFQCCFCQKGFKIQSKLLKHKQIHTRNKAFRALLLKK--RR 253 +F + ++L HQ H+ E+P++C C K F++ +L +H++ HT K F K RR Sbjct: 509 AFNRGSNLVQHQSIHTGEKPYECKECGKAFRLHLQLSQHEKTHTGEKPFECKECGKFFRR 568 Query: 254 TESRPLPNKLNANQGGFENGEIGESEENNPLDVHSIYIV-------PFQCPKCEKCFESE 306 + ++ + FE E G++ L +H I PF+C +C K F Sbjct: 569 GSNLNQHRSIHTGKKPFECKECGKAFR---LHMHLIRHQKFHTGEKPFECKECGKAFSLH 625 Query: 307 QILNEHSCFAARSGKIPSRFK---RSYNYKTIVKKILAKLKRARSKKLDNFQSEKKVFKK 363 LN H +G+ P + K +S+N ++ L + +S E K K Sbjct: 626 TQLNHHKNI--HTGEKPFKCKECGKSFNR-------VSNLVQHQSIHAGVKPYECKECGK 676 Query: 364 SFLRNCDLISGEQSSEQTQRTFVGSLGKHGT---YKTIGNRKKKTLTLPFSWQNMGKNLK 420 F R +LI Q + + + FV + Y+ + + T PF + GK Sbjct: 677 GFSRVSNLIQ-HQKTHSSAKPFVCKECRKTFRYHYQLTEHYRIHTGEKPFECKECGKAF- 734 Query: 421 GILTTENILSIDNSVNKKDLSICGSSGEEFFNNCEVLQCGFSVPRENIRTRHKICPCDKC 480 G+LT + I T K C +C Sbjct: 735 GLLTQ------------------------------------LAQHQIIHTGEKPFKCKEC 758 Query: 481 EKVFPSISKLKRHYLIHTGQRPFGCNICGKSFRQSAHLKRHEQTHNEKSP 530 K F S L + IHTG++P+ C CGK+FR L H++ ++P Sbjct: 759 GKAFNRGSNLVQPQSIHTGEKPYECKECGKAFRLHLQLSLHQKLVQVRNP 808 Score = 150 bits (379), Expect = 4e-36 Identities = 139/563 (24%), Positives = 233/563 (41%), Gaps = 87/563 (15%) Query: 181 IHTGQRPFKCVLCTKSFRQSTHLKIHQLTHSEERPFQCCFCQKGFKIQSKLLKHKQIHTR 240 IH +P++C C K F ++L HQ H+ E+P++C C K F++ +L +H++ HT Sbjct: 158 IHNTHKPYECKECGKYFSCGSNLIQHQSIHTGEKPYKCKECGKAFQLHIQLTRHQKFHTG 217 Query: 241 NKAFRALLLKKRRTESRPLPNKLNANQG------GFENGEIGES--EENNPLDVHSIY-- 290 K F K ++ LP +LN ++ FE E G+S +N SI+ Sbjct: 218 EKTFEC----KECGKAFNLPTQLNRHKNIHTVKKLFECKECGKSFNRSSNLTQHQSIHAG 273 Query: 291 IVPFQCPKCEKCFESEQILNEH-------------SCFAA-------------RSGKIPS 324 + P+QC +C K F L +H C A +G+ P Sbjct: 274 VKPYQCKECGKAFNRGSNLIQHQKIHSNEKPFVCRECEMAFRYHYQLIEHCRIHTGEKPF 333 Query: 325 RFKRSYNYKTIVKKILAKLKRARSKKLDNFQSEKKVFK--KSFLRNCDLISGEQSSE--Q 380 K T++ K++ K +K + K F R+ ++ +GE+ E + Sbjct: 334 ECKECRKAFTLLTKLVRHQKIHMGEKPFECRECGKAFSLLNQLNRHKNIHTGEKPFECKE 393 Query: 381 TQRTFVGSLGKHGTYKTIGNRKKKTLTLPFSWQNMGKNLK---GILTTENILSIDNSVNK 437 ++F + + I ++ P+ + GK ++ + I S + Sbjct: 394 CGKSF------NRSSNLIQHQSIHADVKPYECKECGKGFNRGANLIQHQKIHSNEKPFVC 447 Query: 438 KDLSICGSSGEEFFNNCEV---------LQCG--FSV-----PRENIRTRHKICPCDKCE 481 ++ + + +C++ +CG FS+ +NI T K C C Sbjct: 448 RECEMAFRYHYQLIQHCQIHTGGKPFECKECGKAFSLLTQLARHKNIHTGEKPFECKDCG 507 Query: 482 KVFPSISKLKRHYLIHTGQRPFGCNICGKSFRQSAHLKRHEQTHNEKSPYASLCQVEFGN 541 K F S L +H IHTG++P+ C CGK+FR L +HE+TH + P+ C+ E G Sbjct: 508 KAFNRGSNLVQHQSIHTGEKPYECKECGKAFRLHLQLSQHEKTHTGEKPFE--CK-ECGK 564 Query: 542 FNNLSNHSGNNVNYNASQQCQAPGVQKYEVSESDQMSGVKAESQDFIPGSTGQPCLPNVL 601 F G+N+N + S + E ++ ++ Q F G C Sbjct: 565 F----FRRGSNLNQHRSIHTGKKPFECKECGKAFRLHMHLIRHQKFHTGEKPFEC----- 615 Query: 602 LESEQSNPFCSYSEHQEKNDVFL----YRCSVCAKSFRSPSKLERHYLIHAGQKPFECSV 657 E F +++ ++ ++C C KSF S L +H IHAG KP+EC Sbjct: 616 --KECGKAFSLHTQLNHHKNIHTGEKPFKCKECGKSFNRVSNLVQHQSIHAGVKPYECKE 673 Query: 658 CGKTFRQAPHWKRHQLTHFKERP 680 CGK F + + +HQ TH +P Sbjct: 674 CGKGFSRVSNLIQHQKTHSSAKP 696 Score = 107 bits (266), Expect = 5e-23 Identities = 63/217 (29%), Positives = 104/217 (47%), Gaps = 11/217 (5%) Query: 25 RPYVCNICFKHFETPSKLARHYLIHTGQKPFECDVCHKTFRQLVHLERHQLTHS--LPFK 82 +P+ C C K F ++L H IHTG+KPF+C C K+F ++ +L +HQ H+ P++ Sbjct: 611 KPFECKECGKAFSLHTQLNHHKNIHTGEKPFKCKECGKSFNRVSNLVQHQSIHAGVKPYE 670 Query: 83 CSICQRHFKNLKTFVKHQQLHNETYQNNVKQVRRLLEAKQEKSMYGVYNTFTTEERWALH 142 C C + F + ++HQ+ H+ K+ R+ + + + Y T E+ + Sbjct: 671 CKECGKGFSRVSNLIQHQKTHSSAKPFVCKECRKTFRYHYQLTEH--YRIHTGEKPFECK 728 Query: 143 PCSKSDPMYS-MKRRKNIHA------CTICGKMFPSQSKLDRHVLIHTGQRPFKCVLCTK 195 C K+ + + + + + IH C CGK F S L + IHTG++P++C C K Sbjct: 729 ECGKAFGLLTQLAQHQIIHTGEKPFKCKECGKAFNRGSNLVQPQSIHTGEKPYECKECGK 788 Query: 196 SFRQSTHLKIHQLTHSEERPFQCCFCQKGFKIQSKLL 232 +FR L +HQ P + I S LL Sbjct: 789 AFRLHLQLSLHQKLVQVRNPLNVRNVGQPSDISSNLL 825 >gi|119120877 zinc finger protein 721 [Homo sapiens] Length = 923 Score = 219 bits (559), Expect = 5e-57 Identities = 182/698 (26%), Positives = 299/698 (42%), Gaps = 126/698 (18%) Query: 27 YVCNICFKHFETPSKLARHYLIHTGQKPFECDVCHKTFRQLVHLERHQLTHS--LPFKCS 84 + CN C K F+ S L +H IH G+KP+ C+ K F L +H+ H+ P+KC Sbjct: 109 FKCNECGKSFQKFSDLTQHKGIHAGEKPYTCEERGKDFGWYTDLNQHKKIHTGEKPYKCE 168 Query: 85 ICQRHFKNLKTFVKHQQLHNETYQNNVKQVRRLLEAKQEKSMYGVYNTFTTEERWALHPC 144 C + F H+++HN +EK+ +T E+R Sbjct: 169 ECGKAFNRSTNLTAHKRIHN-----------------REKA-------YTGEDRDRAFGW 204 Query: 145 SKSDPMYSMKRRKNIHA------CTICGKMFPSQSKLDRHVLIHTGQRPFKCVLCTKSFR 198 S ++ K IH C CGK F S L++H IHTG++P+KC C K Sbjct: 205 ST-----NLNEYKKIHTGDKPYKCKECGKAFMHSSHLNKHEKIHTGEKPYKCKECGKVIS 259 Query: 199 QSTHLKIHQLTHSEERPFQCCFCQKGFKIQSKLLKHKQIHTRNKAFRALLLKK--RRTES 256 S+ H+ H+ E+PF+C C K F I + L KH++IHT K + + K R++ + Sbjct: 260 SSSSFAKHKRIHTGEKPFKCLECGKAFNISTTLTKHRRIHTGEKPYTCEVCGKAFRQSAN 319 Query: 257 RPLPNKLNANQGGFENGEIGES-EENNPLDVHSIYIV---PFQCPKCEKCFESEQILNEH 312 + +++ + + GE G++ ++ L VH P++C C K F LN+H Sbjct: 320 LYVHRRIHTGEKPYTCGECGKTFRQSANLYVHRRIHTGEKPYKCEDCGKAFGRYTALNQH 379 Query: 313 SCFAARSGKIPSRFK---RSYNYKTIV---KKILAKLK------RARSKKLD-NFQSEKK 359 +G+ P + + +++N T + K+I + K R R+ L N KK Sbjct: 380 K--KIHTGEKPYKCEECGKAFNSSTNLTAHKRIHTREKPYTCEDRGRAFGLSTNLNEYKK 437 Query: 360 VFKKSFLRNCDLISGEQSSEQTQRTFVGS--LGKHGTYKTIGNRKKKTLTLPFSWQNMGK 417 + C ++ + F+ S L KH K T P+ + GK Sbjct: 438 IHTGDKPYKC---------KECGKAFIHSLHLNKH--------EKIHTGKKPYKCKQCGK 480 Query: 418 NLKGILTTENILSIDNSVNKKDLSICGSSGEEFFNNCEVLQCGFSVPRENIRTRH----- 472 ++T+ + + ++ +GE+ F E L+CG + T+H Sbjct: 481 ----VITSSSSFAKHKRIH---------TGEKPF---ECLECGKAFTSSTTLTKHRRIHT 524 Query: 473 --KICPCDKCEKVFPSISKLKRHYLIHTGQRPFGCNICGKSFRQSAHLKRHEQTHNEKSP 530 K C+ C K F + L H IHTG++P+ C CGK+FRQSA+L H + H + P Sbjct: 525 GEKPYTCEVCGKAFRQSAILYVHRRIHTGEKPYTCEECGKTFRQSANLYVHRRIHTGEKP 584 Query: 531 Y-ASLCQVEFGNFNNLSNHSGNNVNYNASQQCQAPGVQKYEVSESDQMSGVKAESQDFIP 589 Y C FG + +L+ H + +C+ G ++ +Q + + + Sbjct: 585 YKCEECGKAFGRYTDLNQHKKIHTG-EKLYKCEECGKDFVWYTDLNQQKKIYTGEKPYKC 643 Query: 590 GSTGQPCLPNV-------LLESEQSNPFCSYSEHQEKNDVFLYRCSVCAKSFRSPSKLER 642 G+ P+ +L EQS Y+C C K+F L + Sbjct: 644 EECGKAFAPSTDLNQHTKILTGEQS-----------------YKCEECGKAFGWSIALNQ 686 Query: 643 HYLIHAGQKPFECSVCGKTFRQAPHWKRHQLTHFKERP 680 H IH G+KP++C CGK F ++ + H+ H +E+P Sbjct: 687 HKKIHTGEKPYKCEECGKAFSRSRNLTTHRRVHTREKP 724 Score = 213 bits (541), Expect = 6e-55 Identities = 177/680 (26%), Positives = 282/680 (41%), Gaps = 96/680 (14%) Query: 25 RPYVCNICFKHFETPSKLARHYLIHTGQKPFECDVCHKTFRQLVHLERHQLTHS--LPFK 82 +PY C +C K F + L H IHTG+KP+ C C KTFRQ +L H+ H+ P+K Sbjct: 303 KPYTCEVCGKAFRQSANLYVHRRIHTGEKPYTCGECGKTFRQSANLYVHRRIHTGEKPYK 362 Query: 83 CSICQRHFKNLKTFVKHQQLHNETYQNNVKQVRRLLEAKQEKSMYGVYNT----FTTEER 138 C C + F +H+++H ++ + + + + +T +T E+R Sbjct: 363 CEDCGKAFGRYTALNQHKKIHTGEKPYKCEECGKAFNSSTNLTAHKRIHTREKPYTCEDR 422 Query: 139 WALHPCSKSDPMYSMKRRKNIHA------CTICGKMFPSQSKLDRHVLIHTGQRPFKCVL 192 S + + K IH C CGK F L++H IHTG++P+KC Sbjct: 423 GRAFGLSTN-----LNEYKKIHTGDKPYKCKECGKAFIHSLHLNKHEKIHTGKKPYKCKQ 477 Query: 193 CTKSFRQSTHLKIHQLTHSEERPFQCCFCQKGFKIQSKLLKHKQIHTRNKAFRALLLKKR 252 C K S+ H+ H+ E+PF+C C K F + L KH++IHT K + + K Sbjct: 478 CGKVITSSSSFAKHKRIHTGEKPFECLECGKAFTSSTTLTKHRRIHTGEKPYTCEVCGKA 537 Query: 253 RTESRPL--PNKLNANQGGFENGEIGES-EENNPLDVHSIYIV---PFQCPKCEKCFESE 306 +S L +++ + + E G++ ++ L VH P++C +C K F Sbjct: 538 FRQSAILYVHRRIHTGEKPYTCEECGKTFRQSANLYVHRRIHTGEKPYKCEECGKAFGRY 597 Query: 307 QILNEHSCFAARSGKIPSRFKRSYNYKTIVKKILAKLKRARSKKLDNFQSEKKVFK--KS 364 LN+H KI + ++ Y + K + + KK+ + K + K+ Sbjct: 598 TDLNQHK-------KIHTG-EKLYKCEECGKDFVWYTDLNQQKKIYTGEKPYKCEECGKA 649 Query: 365 FLRNCDL------ISGEQSSEQTQRTFVGSLGKHGTYKTIGNRKKKTLT--LPFSWQNMG 416 F + DL ++GEQS + + GK + N+ KK T P+ + G Sbjct: 650 FAPSTDLNQHTKILTGEQSYKCEE------CGKAFGWSIALNQHKKIHTGEKPYKCEECG 703 Query: 417 KNLKGILTTENILSIDNSVNKKDLSICGSSGEEFFNNCEVLQCGFSVPRENIRTRHKICP 476 K + N+ + ++ C G F + + + + I T K+ Sbjct: 704 KAFS---RSRNLTTHRRVHTREKPYKCEDRGRSFGWSTNLNEY------KKIHTGDKLYK 754 Query: 477 CDKCEKVFPSISKLKRHYLIHTGQRPFGCNICGKSFRQSAHLKRHEQTHNEKSPYASL-C 535 C +C KVF S L RH IHTG++P+ C CGK S+ +H++ H + P+ L C Sbjct: 755 CKECGKVFKQSSHLNRHEKIHTGKKPYKCKECGKVITSSSSFAKHKRIHTGEKPFKCLEC 814 Query: 536 QVEFGNFNNLSNHSGNNVNYNASQQCQAPGVQKYEVSESDQMSGVKAESQDFIPGSTGQP 595 F + L+ H + G + Y E KA Q I Sbjct: 815 GKAFTSSTTLTKHRRIHT-----------GEKPYTCEECG-----KAFRQSAI------- 851 Query: 596 CLPNVLLESEQSNPFCSYSEHQEKNDVFLYRCSVCAKSFRSPSKLERHYLIHAGQKPFEC 655 Y + Y C C K+FR + L H IH G+KP+ C Sbjct: 852 ----------------LYVHRRIHTGEKPYTCGECGKTFRQSANLYAHKKIHTGEKPYTC 895 Query: 656 SVCGKTFRQAPHWKRHQLTH 675 CGKTFRQ+ + H+ H Sbjct: 896 GDCGKTFRQSANLYAHKKIH 915 Score = 198 bits (503), Expect = 2e-50 Identities = 178/711 (25%), Positives = 292/711 (41%), Gaps = 90/711 (12%) Query: 24 NRPYVCNICFKHFETPSKLARHYLIHTGQKPFECDVCHKTFRQLVHLERHQLTHS--LPF 81 ++PY C C K F S L +H IHTG+KP++C C K +H+ H+ PF Sbjct: 218 DKPYKCKECGKAFMHSSHLNKHEKIHTGEKPYKCKECGKVISSSSSFAKHKRIHTGEKPF 277 Query: 82 KCSICQRHFKNLKTFVKHQQLHNETYQNNVKQVRRLLEAKQEKSMYGVYNTFTTEERWAL 141 KC C + F T KH+++H + + +Q ++Y T E+ + Sbjct: 278 KCLECGKAFNISTTLTKHRRIHTGEKPYTCEVCGKAF--RQSANLYVHRRIHTGEKPYTC 335 Query: 142 HPCSK----SDPMYSMKR---RKNIHACTICGKMFPSQSKLDRHVLIHTGQRPFKCVLCT 194 C K S +Y +R + + C CGK F + L++H IHTG++P+KC C Sbjct: 336 GECGKTFRQSANLYVHRRIHTGEKPYKCEDCGKAFGRYTALNQHKKIHTGEKPYKCEECG 395 Query: 195 KSFRQSTHLKIHQLTHSEERPFQCCFCQKGFKIQSKLLKHKQIHTRNKAFRALLLKKRRT 254 K+F ST+L H+ H+ E+P+ C + F + + L ++K+IHT +K ++ K Sbjct: 396 KAFNSSTNLTAHKRIHTREKPYTCEDRGRAFGLSTNLNEYKKIHTGDKPYKCKECGKAFI 455 Query: 255 ESRPLPN--KLNANQGGFENGEIGESEENNPLDVHSIYI----VPFQCPKCEKCFESEQI 308 S L K++ + ++ + G+ ++ I PF+C +C K F S Sbjct: 456 HSLHLNKHEKIHTGKKPYKCKQCGKVITSSSSFAKHKRIHTGEKPFECLECGKAFTSSTT 515 Query: 309 LNEHSCFAARSGKIPSRFKRSYNYKTIVKKILAKLKRARSKKLDNFQSEKKVFKKSFLRN 368 L +H +G+ P + K + + + R + E+ K+F ++ Sbjct: 516 LTKHR--RIHTGEKP--YTCEVCGKAFRQSAILYVHRRIHTGEKPYTCEE--CGKTFRQS 569 Query: 369 CDLISGEQSSEQTQRTFVGSLGK-HGTYKTIGNRKK----------KTLTLPFSWQNMGK 417 +L + + GK G Y + KK + F W Sbjct: 570 ANLYVHRRIHTGEKPYKCEECGKAFGRYTDLNQHKKIHTGEKLYKCEECGKDFVWYTDLN 629 Query: 418 NLKGILTTENILSIDNSVNKKDLSICGSSGEEFFNNCEVLQCGFSVPRENIRTRHKICPC 477 K I T E C G+ F + ++ Q I T + C Sbjct: 630 QQKKIYTGEKPYK------------CEECGKAFAPSTDLNQ------HTKILTGEQSYKC 671 Query: 478 DKCEKVFPSISKLKRHYLIHTGQRPFGCNICGKSFRQSAHLKRHEQTHNEKSPYASLCQV 537 ++C K F L +H IHTG++P+ C CGK+F +S +L H + H + PY C+ Sbjct: 672 EECGKAFGWSIALNQHKKIHTGEKPYKCEECGKAFSRSRNLTTHRRVHTREKPYK--CED 729 Query: 538 E---FGNFNNLSN----HSGNNV--------------NYNASQQCQAPGVQKYEVSESDQ 576 FG NL+ H+G+ + + N ++ G + Y+ E + Sbjct: 730 RGRSFGWSTNLNEYKKIHTGDKLYKCKECGKVFKQSSHLNRHEKIHT-GKKPYKCKECGK 788 Query: 577 M---SGVKAESQDFIPGSTGQPCLPNVLLESEQSNPFCSYSEHQEKNDVFL----YRCSV 629 + S A+ + G CL E F S + + + Y C Sbjct: 789 VITSSSSFAKHKRIHTGEKPFKCL-------ECGKAFTSSTTLTKHRRIHTGEKPYTCEE 841 Query: 630 CAKSFRSPSKLERHYLIHAGQKPFECSVCGKTFRQAPHWKRHQLTHFKERP 680 C K+FR + L H IH G+KP+ C CGKTFRQ+ + H+ H E+P Sbjct: 842 CGKAFRQSAILYVHRRIHTGEKPYTCGECGKTFRQSANLYAHKKIHTGEKP 892 Score = 194 bits (494), Expect = 2e-49 Identities = 170/703 (24%), Positives = 277/703 (39%), Gaps = 100/703 (14%) Query: 23 RNRPYVCNICFKHFETPSKLARHYLIHTGQKPFECDVCHKTFRQLVHLERHQLTHS--LP 80 R + Y + F + L + IHTG KP++C C K F HL +H+ H+ P Sbjct: 189 REKAYTGEDRDRAFGWSTNLNEYKKIHTGDKPYKCKECGKAFMHSSHLNKHEKIHTGEKP 248 Query: 81 FKCSICQRHFKNLKTFVKHQQLHNETYQNNVKQVRRLLEAKQEKSMYGVYNTFTTEERWA 140 +KC C + + +F KH+++H ++ + LE + + + T T R Sbjct: 249 YKCKECGKVISSSSSFAKHKRIHTG------EKPFKCLECGK---AFNISTTLTKHRR-- 297 Query: 141 LHPCSKSDPMYSMKRRKNIHACTICGKMFPSQSKLDRHVLIHTGQRPFKCVLCTKSFRQS 200 +H K + C +CGK F + L H IHTG++P+ C C K+FRQS Sbjct: 298 IHTGEKP------------YTCEVCGKAFRQSANLYVHRRIHTGEKPYTCGECGKTFRQS 345 Query: 201 THLKIHQLTHSEERPFQCCFCQKGFKIQSKLLKHKQIHTRNKAFR-----------ALLL 249 +L +H+ H+ E+P++C C K F + L +HK+IHT K ++ L Sbjct: 346 ANLYVHRRIHTGEKPYKCEDCGKAFGRYTALNQHKKIHTGEKPYKCEECGKAFNSSTNLT 405 Query: 250 KKRRTESRPLPNKLNANQGGFENGEIGESEENNPLDVHSIYIVPFQCPKCEKCFESEQIL 309 +R +R P F G S N P++C +C K F L Sbjct: 406 AHKRIHTREKPYTCEDRGRAF-----GLSTNLNEYKKIHTGDKPYKCKECGKAFIHSLHL 460 Query: 310 NEHSCFAARSGKIPSRFKRSYNYKTIVKKILAKLKRARSKKLDNFQSEKKVFK--KSFLR 367 N+H +GK P Y K K I + A+ K++ + + + K+F Sbjct: 461 NKHE--KIHTGKKP------YKCKQCGKVITSSSSFAKHKRIHTGEKPFECLECGKAFTS 512 Query: 368 NCDLISGEQSSEQTQRTFVGSLGKHGTYKTI--GNRKKKTLTLPFSWQNMGKNLKGILTT 425 + L + + GK I +R+ T P++ + GK + Sbjct: 513 STTLTKHRRIHTGEKPYTCEVCGKAFRQSAILYVHRRIHTGEKPYTCEECGKTFRQSANL 572 Query: 426 ENILSIDNSVNKKDLSICGS---------------SGEEFFNNCEVLQCGFSV------- 463 I CG +GE+ + CE +CG Sbjct: 573 YVHRRIHTGEKPYKCEECGKAFGRYTDLNQHKKIHTGEKLY-KCE--ECGKDFVWYTDLN 629 Query: 464 PRENIRTRHKICPCDKCEKVFPSISKLKRHYLIHTGQRPFGCNICGKSFRQSAHLKRHEQ 523 ++ I T K C++C K F + L +H I TG++ + C CGK+F S L +H++ Sbjct: 630 QQKKIYTGEKPYKCEECGKAFAPSTDLNQHTKILTGEQSYKCEECGKAFGWSIALNQHKK 689 Query: 524 THNEKSPY-ASLCQVEFGNFNNLSNHSGNNVNYNASQQCQAPGVQKYEVSESDQMSGVKA 582 H + PY C F NL+ H + + Y+ + + G Sbjct: 690 IHTGEKPYKCEECGKAFSRSRNLTTHRRVHTR-----------EKPYKCEDRGRSFGWST 738 Query: 583 ESQDFIPGSTGQPCLPNVLLESEQSNPFCSYSEHQEKNDVF-----LYRCSVCAKSFRSP 637 ++ TG + L + ++ S H +++ Y+C C K S Sbjct: 739 NLNEYKKIHTG-----DKLYKCKECGKVFKQSSHLNRHEKIHTGKKPYKCKECGKVITSS 793 Query: 638 SKLERHYLIHAGQKPFECSVCGKTFRQAPHWKRHQLTHFKERP 680 S +H IH G+KPF+C CGK F + +H+ H E+P Sbjct: 794 SSFAKHKRIHTGEKPFKCLECGKAFTSSTTLTKHRRIHTGEKP 836 Score = 167 bits (424), Expect = 2e-41 Identities = 144/538 (26%), Positives = 222/538 (41%), Gaps = 70/538 (13%) Query: 23 RNRPYVCNICFKHFETPSKLARHYLIHTGQKPFECDVCHKTFRQLVHLERHQLTHS--LP 80 R +PY C + F + L + IHTG KP++C C K F +HL +H+ H+ P Sbjct: 413 REKPYTCEDRGRAFGLSTNLNEYKKIHTGDKPYKCKECGKAFIHSLHLNKHEKIHTGKKP 472 Query: 81 FKCSICQRHFKNLKTFVKHQQLHNETYQNNVKQVRRLLEAKQEKSMYGVYNTFTTEERWA 140 +KC C + + +F KH+++H + E + + T T R Sbjct: 473 YKCKQCGKVITSSSSFAKHKRIHTG---------EKPFECLECGKAFTSSTTLTKHRR-- 521 Query: 141 LHPCSKSDPMYSMKRRKNIHACTICGKMFPSQSKLDRHVLIHTGQRPFKCVLCTKSFRQS 200 +H K + C +CGK F + L H IHTG++P+ C C K+FRQS Sbjct: 522 IHTGEKP------------YTCEVCGKAFRQSAILYVHRRIHTGEKPYTCEECGKTFRQS 569 Query: 201 THLKIHQLTHSEERPFQCCFCQKGFKIQSKLLKHKQIHTRNKAFRALLLKKRRTESRPL- 259 +L +H+ H+ E+P++C C K F + L +HK+IHT K ++ K L Sbjct: 570 ANLYVHRRIHTGEKPYKCEECGKAFGRYTDLNQHKKIHTGEKLYKCEECGKDFVWYTDLN 629 Query: 260 -PNKLNANQGGFENGEIGES-EENNPLDVHSIYIVPFQCPKCEKC---FESEQILNEHSC 314 K+ + ++ E G++ + L+ H+ + Q KCE+C F LN+H Sbjct: 630 QQKKIYTGEKPYKCEECGKAFAPSTDLNQHTKILTGEQSYKCEECGKAFGWSIALNQHK- 688 Query: 315 FAARSGKIPSR-------FKRSYNYKTIVKKILAKLK------RARSKKLD-NFQSEKKV 360 +G+ P + F RS N T +++ + K R RS N KK+ Sbjct: 689 -KIHTGEKPYKCEECGKAFSRSRNLTTH-RRVHTREKPYKCEDRGRSFGWSTNLNEYKKI 746 Query: 361 FKKSFLRNCDLISG--EQSSEQTQRTFVGSLGKHGTYKTIG-----------NRKKKTLT 407 L C +QSS + + + K K G +++ T Sbjct: 747 HTGDKLYKCKECGKVFKQSSHLNRHEKIHTGKKPYKCKECGKVITSSSSFAKHKRIHTGE 806 Query: 408 LPFSWQNMGKNLKGILTTENILSIDNSVNKKDLSICGSSGEEFFNNCEVLQCGFSVPREN 467 PF GK T I CG + F +L Sbjct: 807 KPFKCLECGKAFTSSTTLTKHRRIHTGEKPYTCEECGKA----FRQSAILYV-----HRR 857 Query: 468 IRTRHKICPCDKCEKVFPSISKLKRHYLIHTGQRPFGCNICGKSFRQSAHLKRHEQTH 525 I T K C +C K F + L H IHTG++P+ C CGK+FRQSA+L H++ H Sbjct: 858 IHTGEKPYTCGECGKTFRQSANLYAHKKIHTGEKPYTCGDCGKTFRQSANLYAHKKIH 915 Score = 155 bits (391), Expect = 2e-37 Identities = 150/598 (25%), Positives = 239/598 (39%), Gaps = 111/598 (18%) Query: 121 KQEKSMYGVYNTFTTEERWALHPCSKSDPMYSM----KRRKNIHA------CTICGKMFP 170 K +K +Y N + + + C+ ++S + K H C CGK F Sbjct: 60 KVQKGVYNGINKCLSNTQSKIFQCNARVKVFSKFANSNKDKTRHTGEKHFKCNECGKSFQ 119 Query: 171 SQSKLDRHVLIHTGQRPFKCVLCTKSFRQSTHLKIHQLTHSEERPFQCCFCQKGFKIQSK 230 S L +H IH G++P+ C K F T L H+ H+ E+P++C C K F + Sbjct: 120 KFSDLTQHKGIHAGEKPYTCEERGKDFGWYTDLNQHKKIHTGEKPYKCEECGKAFNRSTN 179 Query: 231 LLKHKQIHTRNKAFRALLLKKRRTESRPLPNKLNANQGGFENGEIGESEENNPLDVHSIY 290 L HK+IH R KA+ E R + N ++ G+ Sbjct: 180 LTAHKRIHNREKAYTG--------EDRDRAFGWSTNLNEYKKIHTGDK------------ 219 Query: 291 IVPFQCPKCEKCFESEQILNEHSCFAARSGKIPSRFKRSYNYKTIVKKILAKLKRARSKK 350 P++C +C K F LN+H +G+ P Y K K I + A+ K+ Sbjct: 220 --PYKCKECGKAFMHSSHLNKHE--KIHTGEKP------YKCKECGKVISSSSSFAKHKR 269 Query: 351 LDNFQSEKKVFKKSFLRNCDLISGEQSSEQTQRTFVGSLGKHGTYKTIGNRKKKTLTLPF 410 + + +K FK C L G+ + T +L KH R+ T P+ Sbjct: 270 I---HTGEKPFK------C-LECGKAFNIST------TLTKH--------RRIHTGEKPY 305 Query: 411 SWQNMGKNLKGILTTENILSIDNSVNKKDLSICGSSGEEFFNNCEVLQCGFSVPRENIRT 470 + + GK + + N+ + CG G+ F + + I T Sbjct: 306 TCEVCGKAFR---QSANLYVHRRIHTGEKPYTCGECGKTFRQSANL------YVHRRIHT 356 Query: 471 RHKICPCDKCEKVFPSISKLKRHYLIHTGQRPFGCNICGKSFRQSAHLKRHEQTHNEKSP 530 K C+ C K F + L +H IHTG++P+ C CGK+F S +L H++ H + P Sbjct: 357 GEKPYKCEDCGKAFGRYTALNQHKKIHTGEKPYKCEECGKAFNSSTNLTAHKRIHTREKP 416 Query: 531 YASLCQVE---FGNFNNLSN----HSG--------------NNVNYNASQQCQAPGVQKY 569 Y C+ FG NL+ H+G ++++ N ++ G + Y Sbjct: 417 YT--CEDRGRAFGLSTNLNEYKKIHTGDKPYKCKECGKAFIHSLHLNKHEKIHT-GKKPY 473 Query: 570 EVSESDQM---SGVKAESQDFIPGSTGQPCLPNVLLESEQSNPFCSYSEHQEKNDVFL-- 624 + + ++ S A+ + G CL E F S + + + Sbjct: 474 KCKQCGKVITSSSSFAKHKRIHTGEKPFECL-------ECGKAFTSSTTLTKHRRIHTGE 526 Query: 625 --YRCSVCAKSFRSPSKLERHYLIHAGQKPFECSVCGKTFRQAPHWKRHQLTHFKERP 680 Y C VC K+FR + L H IH G+KP+ C CGKTFRQ+ + H+ H E+P Sbjct: 527 KPYTCEVCGKAFRQSAILYVHRRIHTGEKPYTCEECGKTFRQSANLYVHRRIHTGEKP 584 Score = 145 bits (365), Expect = 2e-34 Identities = 128/493 (25%), Positives = 209/493 (42%), Gaps = 60/493 (12%) Query: 25 RPYVCNICFKHFETPSKLARHYLIHTGQKPFECDVCHKTFRQLVHLERHQLTHS--LPFK 82 +PY C C K + S A+H IHTG+KPFEC C K F L +H+ H+ P+ Sbjct: 471 KPYKCKQCGKVITSSSSFAKHKRIHTGEKPFECLECGKAFTSSTTLTKHRRIHTGEKPYT 530 Query: 83 CSICQRHFKNLKTFVKHQQLHNETYQNNVKQVRRLLEAKQEKSMYGVYNTFTTEERWALH 142 C +C + F+ H+++H ++ + +Q ++Y T E+ + Sbjct: 531 CEVCGKAFRQSAILYVHRRIHTGEKPYTCEECGKTF--RQSANLYVHRRIHTGEKPYKCE 588 Query: 143 PCSKSDPMYS-MKRRKNIHA------CTICGKMFPSQSKLDRHVLIHTGQRPFKCVLCTK 195 C K+ Y+ + + K IH C CGK F + L++ I+TG++P+KC C K Sbjct: 589 ECGKAFGRYTDLNQHKKIHTGEKLYKCEECGKDFVWYTDLNQQKKIYTGEKPYKCEECGK 648 Query: 196 SFRQSTHLKIHQLTHSEERPFQCCFCQKGFKIQSKLLKHKQIHTRNKAFRALLLKKRRTE 255 +F ST L H + E+ ++C C K F L +HK+IHT K ++ K + Sbjct: 649 AFAPSTDLNQHTKILTGEQSYKCEECGKAFGWSIALNQHKKIHTGEKPYKCEECGKAFSR 708 Query: 256 SRPLPN--KLNANQGGFENGEIGESE--ENNPLDVHSIYIVP--FQCPKCEKCFESEQIL 309 SR L +++ + ++ + G S N + I+ ++C +C K F+ L Sbjct: 709 SRNLTTHRRVHTREKPYKCEDRGRSFGWSTNLNEYKKIHTGDKLYKCKECGKVFKQSSHL 768 Query: 310 NEHSCFAARSGKIPSRFKRSYNYKTIVKKILAKLKRARSKKLDNFQSEKKVFKKSFLRNC 369 N H +GK P Y K K I + A+ K++ + +K FK C Sbjct: 769 NRHE--KIHTGKKP------YKCKECGKVITSSSSFAKHKRI---HTGEKPFK------C 811 Query: 370 DLISGEQSSEQTQRTFVGSLGKHGTYKTIGNRKKKTLTLPFSWQNMGKNLKGILTTENIL 429 L G+ + T +L KH R+ T P++ + GK + IL Sbjct: 812 -LECGKAFTSST------TLTKH--------RRIHTGEKPYTCEECGKAFR----QSAIL 852 Query: 430 SIDNSVNKKDLSI-CGSSGEEFFNNCEVLQCGFSVPRENIRTRHKICPCDKCEKVFPSIS 488 + ++ + CG G+ F + + + I T K C C K F + Sbjct: 853 YVHRRIHTGEKPYTCGECGKTFRQSANLYA------HKKIHTGEKPYTCGDCGKTFRQSA 906 Query: 489 KLKRHYLIHTGQR 501 L H IHTG + Sbjct: 907 NLYAHKKIHTGDK 919 Score = 123 bits (309), Expect = 5e-28 Identities = 73/233 (31%), Positives = 112/233 (48%), Gaps = 11/233 (4%) Query: 21 LPRNRPYVCNICFKHFETPSKLARHYLIHTGQKPFECDVCHKTFRQLVHLERHQLTHSL- 79 L + Y C C K F L +H IHTG+KP++C+ C K F + +L H+ H+ Sbjct: 663 LTGEQSYKCEECGKAFGWSIALNQHKKIHTGEKPYKCEECGKAFSRSRNLTTHRRVHTRE 722 Query: 80 -PFKCSICQRHFKNLKTFVKHQQLHNETYQNNVKQVRRLLEAKQEKSMYGVYNTFTTEER 138 P+KC R F +++++H K+ ++ KQ + T ++ Sbjct: 723 KPYKCEDRGRSFGWSTNLNEYKKIHTGDKLYKCKECGKVF--KQSSHLNRHEKIHTGKKP 780 Query: 139 WALHPCSKS-DPMYSMKRRKNIHA------CTICGKMFPSQSKLDRHVLIHTGQRPFKCV 191 + C K S + K IH C CGK F S + L +H IHTG++P+ C Sbjct: 781 YKCKECGKVITSSSSFAKHKRIHTGEKPFKCLECGKAFTSSTTLTKHRRIHTGEKPYTCE 840 Query: 192 LCTKSFRQSTHLKIHQLTHSEERPFQCCFCQKGFKIQSKLLKHKQIHTRNKAF 244 C K+FRQS L +H+ H+ E+P+ C C K F+ + L HK+IHT K + Sbjct: 841 ECGKAFRQSAILYVHRRIHTGEKPYTCGECGKTFRQSANLYAHKKIHTGEKPY 893 Score = 120 bits (300), Expect = 6e-27 Identities = 70/232 (30%), Positives = 108/232 (46%), Gaps = 39/232 (16%) Query: 23 RNRPYVCNICFKHFETPSKLARHYLIHTGQKPFECDVCHKTFRQLVHLERHQLTHS--LP 80 R +PY C + F + L + IHTG K ++C C K F+Q HL RH+ H+ P Sbjct: 721 REKPYKCEDRGRSFGWSTNLNEYKKIHTGDKLYKCKECGKVFKQSSHLNRHEKIHTGKKP 780 Query: 81 FKCSICQRHFKNLKTFVKHQQLHNETYQNNVKQVRRLLEAKQEKSMYGVYNTFTTEERWA 140 +KC C + + +F KH+++H T E+ + Sbjct: 781 YKCKECGKVITSSSSFAKHKRIH------------------------------TGEKPFK 810 Query: 141 LHPCSKS-DPMYSMKRRKNIHA------CTICGKMFPSQSKLDRHVLIHTGQRPFKCVLC 193 C K+ ++ + + IH C CGK F + L H IHTG++P+ C C Sbjct: 811 CLECGKAFTSSTTLTKHRRIHTGEKPYTCEECGKAFRQSAILYVHRRIHTGEKPYTCGEC 870 Query: 194 TKSFRQSTHLKIHQLTHSEERPFQCCFCQKGFKIQSKLLKHKQIHTRNKAFR 245 K+FRQS +L H+ H+ E+P+ C C K F+ + L HK+IHT +K + Sbjct: 871 GKTFRQSANLYAHKKIHTGEKPYTCGDCGKTFRQSANLYAHKKIHTGDKTIQ 922 >gi|150378520 zinc finger protein 594 [Homo sapiens] Length = 807 Score = 219 bits (557), Expect = 9e-57 Identities = 171/653 (26%), Positives = 276/653 (42%), Gaps = 104/653 (15%) Query: 23 RNRPYVCNICFKHFETPSKLARHYLIHTGQKPFECDVCHKTFRQLVHLERHQLTHS--LP 80 R +PY+CN C K F + L H+ IHTG+KP+EC C + F Q HL HQ H+ P Sbjct: 235 RGKPYLCNKCGKAFSQSTDLIIHHRIHTGEKPYECYDCGQMFSQSSHLVPHQRIHTGEKP 294 Query: 81 FKCSICQRHFKNLKTFVKHQQLHNETYQNNVKQVRRLLEAKQEKSMYGVYNTFTTEERWA 140 KC+ C++ F+ +HQ+LH+ + R + ++ + + E+ Sbjct: 295 LKCNECEKAFRQHSHLTEHQRLHS---GEKPYECHRCGKTFSGRTAFLKHQRLHAGEK-- 349 Query: 141 LHPCSKS-DPMYSMKRRKNIHA------CTICGKMFPSQSKLDRHVLIHTGQRPFKCVLC 193 + C K+ ++ + IH C CG+ F S L RH + HTG++P++C C Sbjct: 350 IEECEKTFSKDEELREEQRIHQEEKAYWCNQCGRNFQGTSDLIRHQVTHTGEKPYECKEC 409 Query: 194 TKSFRQSTHLKIHQLTHSEERPFQCCFCQKGFKIQSKLLKHKQIHTRNKAFRALLLKKRR 253 K+F QS+ L H HS E+P C C K F+ S L++H ++HT K + K Sbjct: 410 GKTFNQSSDLLRHHRIHSGEKPCVCSKCGKSFRGSSDLIRHHRVHTGEKPYECSECGKAF 469 Query: 254 TESRPLPNKLNANQGGFENGEIGESEENNPLDVHSIYIVPFQCPKCEKCFESEQILNEHS 313 ++ L + G P+QC +C K F +L +H Sbjct: 470 SQRSHLVTHQKIHTGE----------------------KPYQCTECGKAFRRRSLLIQHR 507 Query: 314 CFAARSGKIPSRFKRSYNYKTIVKKILAKLKRARSKKLDNFQSEKKVFKKSFLRNCDLIS 373 SG+ P Y K K + + + + L EK +K+F ++ +L Sbjct: 508 --RIHSGEKP------YECKECGKLFIWRTAFLKHQSLHT--GEKLECEKTFSQDEEL-R 556 Query: 374 GEQSSEQTQRTFVGSLGKHGTYKTIGNRKKKTLTLPFSWQNM-GKNLKGILTTENILSID 432 GEQ Q + + W N G+ +G + +++ Sbjct: 557 GEQKIHQEAKAY--------------------------WCNQCGRAFQG---SSDLIRHQ 587 Query: 433 NSVNKKDLSICGSSGEEFFNNCEVLQCGFSVPRENIRTRHKICPCDKCEKVFPSISKLKR 492 + ++ C G+ F + ++L+ I + K C+KC K F S L + Sbjct: 588 VTHTREKPYECKECGKTFNQSSDLLR------HHRIHSGEKPYVCNKCGKSFRGSSDLIK 641 Query: 493 HYLIHTGQRPFGCNICGKSFRQSAHLKRHEQTHNEKSPY-ASLCQVEFGNFNNLSNHSGN 551 H+ IHTG++P+ C+ CGK+F Q +HL H++ H + PY S C F + L H Sbjct: 642 HHRIHTGEKPYECSECGKAFSQRSHLATHQKIHTGEKPYQCSECGNAFRRRSLLIQHRRL 701 Query: 552 NVNYNASQQCQAPGVQKYEVSESDQM---SGVKAESQDFIPGSTGQPCLPNVLLESEQSN 608 + G + YE E ++ + Q G + C + E Sbjct: 702 H-----------SGEKPYECKECGKLFMWHTAFLKHQRLHAGEKLEECEKTFSKDEELRK 750 Query: 609 PFCSYSEHQEKNDVFLYRCSVCAKSFRSPSKLERHYLIHAGQKPFECSVCGKT 661 HQEK +Y C+ C+++F+ S L RH + H +KP+EC CGKT Sbjct: 751 ---EQRTHQEKK---VYWCNQCSRTFQGSSDLIRHQVTHTREKPYECKECGKT 797 Score = 209 bits (532), Expect = 7e-54 Identities = 175/677 (25%), Positives = 279/677 (41%), Gaps = 115/677 (16%) Query: 24 NRPYVCNICFKHFETPSKLARHYLIHTGQKPFECDVCHKTFRQLVHLERHQLTHS--LPF 81 N+PYVCN C K S L H IHTG+KP+ C C K F Q +L RH+ HS P+ Sbjct: 152 NKPYVCNECGKDSNQSSNLIIHQRIHTGKKPYICHECGKDFNQSSNLVRHKQIHSGGNPY 211 Query: 82 KCSICQRHFKNLKTFVKHQQLHNETYQNNVKQVRRLLEAKQEKSMYGVYNTFTTEERWAL 141 +C C + FK V HQ++H+ R Sbjct: 212 ECKECGKAFKGSSNLVLHQRIHS---------------------------------RGKP 238 Query: 142 HPCSKSDPMYSMKRRKNIH----------ACTICGKMFPSQSKLDRHVLIHTGQRPFKCV 191 + C+K +S IH C CG+MF S L H IHTG++P KC Sbjct: 239 YLCNKCGKAFSQSTDLIIHHRIHTGEKPYECYDCGQMFSQSSHLVPHQRIHTGEKPLKCN 298 Query: 192 LCTKSFRQSTHLKIHQLTHSEERPFQCCFCQKGFKIQSKLLKHKQIHTRNKAFRALLLKK 251 C K+FRQ +HL HQ HS E+P++C C K F ++ LKH+++H K Sbjct: 299 ECEKAFRQHSHLTEHQRLHSGEKPYECHRCGKTFSGRTAFLKHQRLHAGEKIEECEKTFS 358 Query: 252 RRTESRPLPNKLNANQGGFENGEIGES-EENNPLDVHSIYIV---PFQCPKCEKCF-ESE 306 + E R +++ + + + G + + + L H + P++C +C K F +S Sbjct: 359 KDEELRE-EQRIHQEEKAYWCNQCGRNFQGTSDLIRHQVTHTGEKPYECKECGKTFNQSS 417 Query: 307 QILNEHSCFAARSGKIPSRFKRSYNYKTIVKKILAKLKRARSKKLDNFQSEKKVFKKSFL 366 +L H + + S+ +S+ + + I K + + K ++S L Sbjct: 418 DLLRHHRIHSGEKPCVCSKCGKSFRGSSDL--IRHHRVHTGEKPYECSECGKAFSQRSHL 475 Query: 367 RNCDLI-SGEQSSEQTQRTFVGSLGKHGTYKT--IGNRKKKTLTLPFSWQNMGKNLKGIL 423 I +GE+ + T+ GK ++ I +R+ + P+ + GK + Sbjct: 476 VTHQKIHTGEKPYQCTE------CGKAFRRRSLLIQHRRIHSGEKPYECKECGK----LF 525 Query: 424 TTENILSIDNSVNKKDLSICGSSGEEFFNNCEVLQCGFSVPRENIRTRHKICPCDKCEKV 483 S++ + C E+ F+ E L+ + I K C++C + Sbjct: 526 IWRTAFLKHQSLHTGEKLEC----EKTFSQDEELR-----GEQKIHQEAKAYWCNQCGRA 576 Query: 484 FPSISKLKRHYLIHTGQRPFGCNICGKSFRQSAHLKRHEQTHNEKSPY-ASLCQVEFGNF 542 F S L RH + HT ++P+ C CGK+F QS+ L RH + H+ + PY + C F Sbjct: 577 FQGSSDLIRHQVTHTREKPYECKECGKTFNQSSDLLRHHRIHSGEKPYVCNKCGKSFRGS 636 Query: 543 NNLSNHSGNNVNYNASQQCQAPGVQKYEVSESDQMSGVKAESQDFIPGSTGQPCLPNVLL 602 ++L H + G + YE SE + ++ TG+ Sbjct: 637 SDLIKHHRIHT-----------GEKPYECSECGKAFSQRSHLATHQKIHTGEK------- 678 Query: 603 ESEQSNPFCSYSEHQEKNDVFLYRCSVCAKSFRSPSKLERHYLIHAGQKPFECSVCGKTF 662 Y+CS C +FR S L +H +H+G+KP+EC CGK F Sbjct: 679 ---------------------PYQCSECGNAFRRRSLLIQHRRLHSGEKPYECKECGKLF 717 Query: 663 RQAPHWKRHQLTHFKER 679 + +HQ H E+ Sbjct: 718 MWHTAFLKHQRLHAGEK 734 Score = 192 bits (488), Expect = 9e-49 Identities = 163/666 (24%), Positives = 265/666 (39%), Gaps = 109/666 (16%) Query: 47 LIHTGQKPFECDVCHKTFRQLVHLERHQLTHSL--PFKCSICQRHFKNLKTFVKHQQLHN 104 ++ G+ +V + F+Q L HQ H++ ++C C++ F + HQ++H Sbjct: 91 ILSAGESSHRYEVSGQNFKQKSGLTEHQKIHNINKTYECKECEKTFNRSSNLIIHQRIHT 150 Query: 105 ETYQNNVKQVRRLLEAKQEKSMYGVYNTFTTEERWALHPCSKS-DPMYSMKRRKNIHA-- 161 + + ++ Q ++ T ++ + H C K + ++ R K IH+ Sbjct: 151 GNKPYVCNECGK--DSNQSSNLIIHQRIHTGKKPYICHECGKDFNQSSNLVRHKQIHSGG 208 Query: 162 ----CTICGKMFPSQSKLDRHVLIHTGQRPFKCVLCTKSFRQSTHLKIHQLTHSEERPFQ 217 C CGK F S L H IH+ +P+ C C K+F QST L IH H+ E+P++ Sbjct: 209 NPYECKECGKAFKGSSNLVLHQRIHSRGKPYLCNKCGKAFSQSTDLIIHHRIHTGEKPYE 268 Query: 218 CCFCQKGFKIQSKLLKHKQIHTRNKAFRALLLKKRRTESRPLPNKLNANQGGFENGEIGE 277 C C + F S L+ H++IHT K Sbjct: 269 CYDCGQMFSQSSHLVPHQRIHTGEK----------------------------------- 293 Query: 278 SEENNPLDVHSIYIVPFQCPKCEKCFESEQILNEHSCFAARSGKIP---SRFKRSYNYKT 334 P +C +CEK F L EH SG+ P R ++++ +T Sbjct: 294 ---------------PLKCNECEKAFRQHSHLTEHQ--RLHSGEKPYECHRCGKTFSGRT 336 Query: 335 IVKKILAKLKRARSKKLDNFQSEKKVFKKSFLRNCDLISGEQSSEQTQRTF-VGSLGKH- 392 A LK R + + +K F K + + EQ Q ++ + G++ Sbjct: 337 ------AFLKHQRLHAGEKIEECEKTFSKD-----EELREEQRIHQEEKAYWCNQCGRNF 385 Query: 393 -GTYKTIGNRKKKTLTLPFSWQNMGKNLKGILTTENILSIDNSVNKKDLSICGSSGEEFF 451 GT I ++ T P+ + GK + ++L + + +C G+ F Sbjct: 386 QGTSDLIRHQVTHTGEKPYECKECGKTFN---QSSDLLRHHRIHSGEKPCVCSKCGKSFR 442 Query: 452 NNCEVLQCGFSVPRENIRTRHKICPCDKCEKVFPSISKLKRHYLIHTGQRPFGCNICGKS 511 + ++++ + T K C +C K F S L H IHTG++P+ C CGK+ Sbjct: 443 GSSDLIR------HHRVHTGEKPYECSECGKAFSQRSHLVTHQKIHTGEKPYQCTECGKA 496 Query: 512 FRQSAHLKRHEQTHNEKSPY-----ASLCQVEFGNFNNLSNHSGNNVNYNA--SQQCQAP 564 FR+ + L +H + H+ + PY L + S H+G + SQ + Sbjct: 497 FRRRSLLIQHRRIHSGEKPYECKECGKLFIWRTAFLKHQSLHTGEKLECEKTFSQDEELR 556 Query: 565 GVQKYEVSES----DQMSGVKAESQDFIPGSTGQP------CLPNVLLESEQSNPFCSYS 614 G QK +Q S D I C ++ S+ + Sbjct: 557 GEQKIHQEAKAYWCNQCGRAFQGSSDLIRHQVTHTREKPYECKECGKTFNQSSDLLRHHR 616 Query: 615 EHQEKNDVFLYRCSVCAKSFRSPSKLERHYLIHAGQKPFECSVCGKTFRQAPHWKRHQLT 674 H + Y C+ C KSFR S L +H+ IH G+KP+ECS CGK F Q H HQ Sbjct: 617 IHSGEKP---YVCNKCGKSFRGSSDLIKHHRIHTGEKPYECSECGKAFSQRSHLATHQKI 673 Query: 675 HFKERP 680 H E+P Sbjct: 674 HTGEKP 679 Score = 116 bits (291), Expect = 6e-26 Identities = 68/243 (27%), Positives = 113/243 (46%), Gaps = 14/243 (5%) Query: 25 RPYVCNICFKHFETPSKLARHYLIHTGQKPFECDVCHKTFRQLVHLERHQLTHS--LPFK 82 + Y CN C + F+ S L RH + HT +KP+EC C KTF Q L RH HS P+ Sbjct: 566 KAYWCNQCGRAFQGSSDLIRHQVTHTREKPYECKECGKTFNQSSDLLRHHRIHSGEKPYV 625 Query: 83 CSICQRHFKNLKTFVKHQQLHNETYQNNVKQVRRLLEAKQEKSMYGVYNTFTTEERWALH 142 C+ C + F+ +KH ++H + + + + + T E+ + Sbjct: 626 CNKCGKSFRGSSDLIKHHRIHTGEKPYECSECGKAFSQRSHLATH--QKIHTGEKPYQCS 683 Query: 143 PCSKSDPMYSMK-RRKNIHA------CTICGKMFPSQSKLDRHVLIHTGQRPFKCVLCTK 195 C + S+ + + +H+ C CGK+F + +H +H G+ K C K Sbjct: 684 ECGNAFRRRSLLIQHRRLHSGEKPYECKECGKLFMWHTAFLKHQRLHAGE---KLEECEK 740 Query: 196 SFRQSTHLKIHQLTHSEERPFQCCFCQKGFKIQSKLLKHKQIHTRNKAFRALLLKKRRTE 255 +F + L+ Q TH E++ + C C + F+ S L++H+ HTR K + K ++E Sbjct: 741 TFSKDEELRKEQRTHQEKKVYWCNQCSRTFQGSSDLIRHQVTHTREKPYECKECGKTQSE 800 Query: 256 SRP 258 RP Sbjct: 801 LRP 803 >gi|6005976 zinc finger protein 208 [Homo sapiens] Length = 1167 Score = 218 bits (555), Expect = 1e-56 Identities = 179/686 (26%), Positives = 294/686 (42%), Gaps = 70/686 (10%) Query: 25 RPYVCNICFKHFETPSKLARHYLIHTGQKPFECDVCHKTFRQLVHLERHQLTHS--LPFK 82 + Y C C K F + L +H +IHTG+KP +C+ C K F ++ L H+ H+ P+K Sbjct: 255 KSYKCEECGKAFNQSAILTKHKIIHTGEKPNKCEECGKAFSKVSTLTTHKAIHAGEKPYK 314 Query: 83 CSICQRHFKNLKTFVKHQQLHNETYQNNVKQVRRLLEAKQEKSMYGVYNTFTTEERWALH 142 C C + F + T + H+ +H K+ + + + V +T E+ + Sbjct: 315 CKECGKAFSKVSTLITHKAIHAGEKPYKCKECGKAFSKFSILTKHKVIHT--GEKPYKCE 372 Query: 143 PCSKSDPMYS-MKRRKNIHA------CTICGKMFPSQSKLDRHVLIHTGQRPFKCVLCTK 195 C K+ S + K IH C CGK F S L +H +IHTG++P+KC C K Sbjct: 373 ECGKAYKWPSTLSYHKKIHTGEKPYKCEECGKGFSMFSILTKHEVIHTGEKPYKCEECGK 432 Query: 196 SFRQSTHLKIHQLTHSEERPFQCCFCQKGFKIQSKLLKHKQIHTRNKAFRALLLKKRRTE 255 +F S++L H+ H+ E P++C C KGF S L HK+IHT K ++ K + Sbjct: 433 AFNWSSNLMEHKKIHTGETPYKCEECGKGFSWSSTLSYHKKIHTVEKPYKCEECGKAFNQ 492 Query: 256 SRPL--PNKLNANQGGFENGEIGES-EENNPLDVHSIYIV---PFQCPKCEKCFESEQIL 309 S L +++ + ++ E G++ + + L H P++C +C K F L Sbjct: 493 SAILIKHKRIHTGEKPYKCEECGKTFSKVSTLTTHKAIHAGEKPYKCKECGKTFIKVSTL 552 Query: 310 NEHSCFAA--------RSGKIPSRFKRSYNYKTIVKKILAKLKRARSKKLDNFQSEKKVF 361 H A GK S+F +K ++ K K N+ S Sbjct: 553 TTHKAIHAGEKPYKCKECGKAFSKFSILTKHK-VIHTGEKPYKCEECGKAFNWSSNLMEH 611 Query: 362 KKSFLRNCDLISGEQ--SSEQTQRTF--VGSLGKHGTYKTIGNRKKKTLTLPFSWQNMGK 417 K+ + +GE+ E+ ++F L KH K I +K P+ + GK Sbjct: 612 KR-------IHTGEKPYKCEECGKSFSTFSVLTKH---KVIHTGEK-----PYKCEECGK 656 Query: 418 NLKGILTTENILSIDNSVNKKDLSICGSSGEEFFNNCEVLQCGFSVPRENIRTRHKICPC 477 K T I CG + FN +L + + I T K C Sbjct: 657 AYKWSSTLSYHKKIHTVEKPYKCEECGKA----FNRSAIL-----IKHKRIHTDEKPYKC 707 Query: 478 DKCEKVFPSISKLKRHYLIHTGQRPFGCNICGKSFRQSAHLKRHEQTHNEKSPY-ASLCQ 536 ++C K F +S L H IH G++P+ C CGK+F + + L +H+ H + PY C Sbjct: 708 EECGKTFSKVSTLTTHKAIHAGEKPYKCKECGKAFSKFSILTKHKVIHTGEKPYKCEECG 767 Query: 537 VEFGNFNNLSNHSGNNVNYNASQQCQAPGVQKYEVSESDQMSGVKAESQDFIPGSTGQPC 596 + + LS H + +C+ E + M + + + G C Sbjct: 768 KAYKWPSTLSYHKKIHTG-EKPYKCE-------ECGKGFSMFSILTKHEVIHTGEKPYKC 819 Query: 597 LPNVLLESEQSNPFCS-YSEHQEKN-DVFLYRCSVCAKSFRSPSKLERHYLIHAGQKPFE 654 E ++ + S +S+H++ + Y+C C K++ + S L +H +IH G+KP++ Sbjct: 820 -----EECGKAFSWLSVFSKHKKTHAGEKFYKCEACGKAYNTFSILTKHKVIHTGEKPYK 874 Query: 655 CSVCGKTFRQAPHWKRHQLTHFKERP 680 C CGK F + + H+ H E P Sbjct: 875 CEECGKAFNWSSNLMEHKKIHTGETP 900 Score = 218 bits (554), Expect = 2e-56 Identities = 173/672 (25%), Positives = 293/672 (43%), Gaps = 98/672 (14%) Query: 25 RPYVCNICFKHFETPSKLARHYLIHTGQKPFECDVCHKTFRQLVHLERHQLTHS--LPFK 82 +PY C C K F S L +H +IHTG+K ++C+ C K F Q L +H++ H+ P K Sbjct: 227 KPYRCKECGKAFSKFSILTKHKVIHTGEKSYKCEECGKAFNQSAILTKHKIIHTGEKPNK 286 Query: 83 CSICQRHFKNLKTFVKHQQLHNETYQNNVKQVRRLLEAKQEKSMYGVYNTFTTEERWALH 142 C C + F + T H+ +H + + K+ + +T T + A+H Sbjct: 287 CEECGKAFSKVSTLTTHKAIHAG---------EKPYKCKECGKAFSKVSTLITHK--AIH 335 Query: 143 PCSKSDPMYSMKRRKNIHACTICGKMFPSQSKLDRHVLIHTGQRPFKCVLCTKSFRQSTH 202 K + C CGK F S L +H +IHTG++P+KC C K+++ + Sbjct: 336 AGEKP------------YKCKECGKAFSKFSILTKHKVIHTGEKPYKCEECGKAYKWPST 383 Query: 203 LKIHQLTHSEERPFQCCFCQKGFKIQSKLLKHKQIHTRNKAFRALLLKKRRTESRPLPN- 261 L H+ H+ E+P++C C KGF + S L KH+ IHT K ++ K S L Sbjct: 384 LSYHKKIHTGEKPYKCEECGKGFSMFSILTKHEVIHTGEKPYKCEECGKAFNWSSNLMEH 443 Query: 262 -KLNANQGGFENGEIGESEE-NNPLDVHS-IYIV--PFQCPKCEKCFESEQILNEHSCFA 316 K++ + ++ E G+ ++ L H I+ V P++C +C K F IL +H Sbjct: 444 KKIHTGETPYKCEECGKGFSWSSTLSYHKKIHTVEKPYKCEECGKAFNQSAILIKHK--R 501 Query: 317 ARSGKIPSRFKRSYNYKTIVKKILAKLKRARSKKLDNFQSEKKVFKKSFLRNCDLISGEQ 376 +G+ P + + K +K+ + K + +K +K Sbjct: 502 IHTGEKPYKCEEC-------GKTFSKVSTLTTHKA--IHAGEKPYK-------------- 538 Query: 377 SSEQTQRTFVGSLGKHGTYKTIGNRKKKTLTLPFSWQNMGKNLK--GILTTENILSIDNS 434 ++ +TF+ + T+K I +K P+ + GK ILT ++ Sbjct: 539 -CKECGKTFI-KVSTLTTHKAIHAGEK-----PYKCKECGKAFSKFSILTKHKVIHTGEK 591 Query: 435 VNKKDLSICGSSGEEFFNNCEVLQCGFSVPRENIRTRHKICPCDKCEKVFPSISKLKRHY 494 K C G+ F + +++ + I T K C++C K F + S L +H Sbjct: 592 PYK-----CEECGKAFNWSSNLME------HKRIHTGEKPYKCEECGKSFSTFSVLTKHK 640 Query: 495 LIHTGQRPFGCNICGKSFRQSAHLKRHEQTHNEKSPY-ASLCQVEFGNFNNLSNHSGNNV 553 +IHTG++P+ C CGK+++ S+ L H++ H + PY C F L H + Sbjct: 641 VIHTGEKPYKCEECGKAYKWSSTLSYHKKIHTVEKPYKCEECGKAFNRSAILIKHKRIHT 700 Query: 554 NYNASQQCQAPGVQKYEVSESDQMSGVKAESQDFIPGSTGQPCLPNVLLESEQSNPFCSY 613 + +C+ G +VS + A + + G + + F Sbjct: 701 D-EKPYKCEECGKTFSKVSTLTTHKAIHAGEKPYKCKECG-----------KAFSKFSIL 748 Query: 614 SEHQ-----EKNDVFLYRCSVCAKSFRSPSKLERHYLIHAGQKPFECSVCGKTFRQAPHW 668 ++H+ EK Y+C C K+++ PS L H IH G+KP++C CGK F Sbjct: 749 TKHKVIHTGEKP----YKCEECGKAYKWPSTLSYHKKIHTGEKPYKCEECGKGFSMFSIL 804 Query: 669 KRHQLTHFKERP 680 +H++ H E+P Sbjct: 805 TKHEVIHTGEKP 816 Score = 216 bits (550), Expect = 6e-56 Identities = 176/687 (25%), Positives = 289/687 (42%), Gaps = 100/687 (14%) Query: 25 RPYVCNICFKHFETPSKLARHYLIHTGQKPFECDVCHKTFRQLVHLERHQLTHS--LPFK 82 +PY C C K ++ PS L+ H IHTG+KP++C+ C K F L +H++ H+ P+K Sbjct: 367 KPYKCEECGKAYKWPSTLSYHKKIHTGEKPYKCEECGKGFSMFSILTKHEVIHTGEKPYK 426 Query: 83 CSICQRHFKNLKTFVKHQQLHNETYQNNVKQVRRLLEAKQEKSMYGVYNTFTTEERWALH 142 C C + F ++H+++H ++ + S + +T E+ + Sbjct: 427 CEECGKAFNWSSNLMEHKKIHTGETPYKCEECGKGFSWSSTLSYHKKIHT--VEKPYKCE 484 Query: 143 PCSKS-DPMYSMKRRKNIHA------CTICGKMFPSQSKLDRHVLIHTGQRPFKCVLCTK 195 C K+ + + + K IH C CGK F S L H IH G++P+KC C K Sbjct: 485 ECGKAFNQSAILIKHKRIHTGEKPYKCEECGKTFSKVSTLTTHKAIHAGEKPYKCKECGK 544 Query: 196 SFRQSTHLKIHQLTHSEERPFQCCFCQKGFKIQSKLLKHKQIHTRNKAFRALLLKKRRTE 255 +F + + L H+ H+ E+P++C C K F S L KHK IHT K ++ K Sbjct: 545 TFIKVSTLTTHKAIHAGEKPYKCKECGKAFSKFSILTKHKVIHTGEKPYKCEECGKA--- 601 Query: 256 SRPLPNKLNANQGGFENGEIGESEENNPLDVHSIYIVPFQCPKCEKCFESEQILNEHSCF 315 N + E+ I E+ P++C +C K F + +L +H Sbjct: 602 -------FNWSSNLMEHKRIHTGEK------------PYKCEECGKSFSTFSVLTKH--- 639 Query: 316 AARSGKIPSRFKRSYNYKTIVKKILAKLKRARSKKLDNFQSEKKVFK--KSFLRNCDLIS 373 K+ ++ Y + K + KK+ + K + K+F R+ LI Sbjct: 640 -----KVIHTGEKPYKCEECGKAYKWSSTLSYHKKIHTVEKPYKCEECGKAFNRSAILIK 694 Query: 374 GEQ--------SSEQTQRTFVGSLGKHGTYKTIGNRKKKTLTLPFSWQNMGKNLK--GIL 423 ++ E+ +TF + T+K I +K P+ + GK IL Sbjct: 695 HKRIHTDEKPYKCEECGKTF-SKVSTLTTHKAIHAGEK-----PYKCKECGKAFSKFSIL 748 Query: 424 TTENILSIDNSVNKKDLSICGSSGEEFFNNCEVLQCGFSVP-----RENIRTRHKICPCD 478 T ++ +GE+ + CE + P + I T K C+ Sbjct: 749 TKHKVIH---------------TGEKPYK-CEECGKAYKWPSTLSYHKKIHTGEKPYKCE 792 Query: 479 KCEKVFPSISKLKRHYLIHTGQRPFGCNICGKSFRQSAHLKRHEQTH-NEKSPYASLCQV 537 +C K F S L +H +IHTG++P+ C CGK+F + +H++TH EK C Sbjct: 793 ECGKGFSMFSILTKHEVIHTGEKPYKCEECGKAFSWLSVFSKHKKTHAGEKFYKCEACGK 852 Query: 538 EFGNFNNLSNHSGNNVNYNASQQCQAPGVQKYEVSESDQMSGVKAESQDFIPGSTGQPCL 597 + F+ L+ H + +C+ E ++ S E + G T C Sbjct: 853 AYNTFSILTKHKVIHTG-EKPYKCE-------ECGKAFNWSSNLMEHKKIHTGETPYKC- 903 Query: 598 PNVLLESEQSNPFC---SYSEHQEKN-DVFLYRCSVCAKSFRSPSKLERHYLIHAGQKPF 653 E F S +EH+ + Y+C C K+F PS+L H HAG++P+ Sbjct: 904 ------EECDKAFSWPSSLTEHKATHAGEKPYKCEECGKAFSWPSRLTEHKATHAGEEPY 957 Query: 654 ECSVCGKTFRQAPHWKRHQLTHFKERP 680 +C CGK F + + H+ H E+P Sbjct: 958 KCEECGKAFNWSSNLMEHKRIHTGEKP 984 Score = 213 bits (543), Expect = 4e-55 Identities = 176/697 (25%), Positives = 293/697 (42%), Gaps = 92/697 (13%) Query: 25 RPYVCNICFKHFETPSKLARHYLIHTGQKPFECDVCHKTFRQLVHLERHQLTHS--LPFK 82 +PY C C K F + L +H IHTG+KP++C+ C KTF ++ L H+ H+ P+K Sbjct: 479 KPYKCEECGKAFNQSAILIKHKRIHTGEKPYKCEECGKTFSKVSTLTTHKAIHAGEKPYK 538 Query: 83 CSICQRHFKNLKTFVKHQQLHNETYQNNVKQVRRLLEAKQEKSMYGVYNTFTTEERWALH 142 C C + F + T H+ +H K+ + + + V +T E+ + Sbjct: 539 CKECGKTFIKVSTLTTHKAIHAGEKPYKCKECGKAFSKFSILTKHKVIHT--GEKPYKCE 596 Query: 143 PCSKSDPMYS-MKRRKNIHA------CTICGKMFPSQSKLDRHVLIHTGQRPFKCVLCTK 195 C K+ S + K IH C CGK F + S L +H +IHTG++P+KC C K Sbjct: 597 ECGKAFNWSSNLMEHKRIHTGEKPYKCEECGKSFSTFSVLTKHKVIHTGEKPYKCEECGK 656 Query: 196 SFRQSTHLKIHQLTHSEERPFQCCFCQKGFKIQSKLLKHKQIHTRNKAFRALLLKKRRTE 255 +++ S+ L H+ H+ E+P++C C K F + L+KHK+IHT K ++ K ++ Sbjct: 657 AYKWSSTLSYHKKIHTVEKPYKCEECGKAFNRSAILIKHKRIHTDEKPYKCEECGKTFSK 716 Query: 256 SRPLPNKLNANQGGFENGEIGESEENNPLDVHSIYIVPFQCPKCEKCFESEQILNEHSCF 315 L + G P++C +C K F IL +H Sbjct: 717 VSTLTTHKAIHAGE----------------------KPYKCKECGKAFSKFSILTKHKVI 754 Query: 316 AARSGKIPSRFK---RSYNYKTIV---KKILAKLKRARSKKLDNFQSEKKVFKKSFLRNC 369 +G+ P + + ++Y + + + KKI K + ++ S + K + Sbjct: 755 --HTGEKPYKCEECGKAYKWPSTLSYHKKIHTGEKPYKCEECGKGFSMFSILTKHEV--- 809 Query: 370 DLISGEQSSEQTQRTFVGSLGKHGTYKTIGNRKKKTLTLP--FSWQNMGK--NLKGILTT 425 + +GE+ + + GK ++ ++ ++ KKT + + GK N ILT Sbjct: 810 -IHTGEKPYKCEE------CGKAFSWLSVFSKHKKTHAGEKFYKCEACGKAYNTFSILTK 862 Query: 426 ENILSIDNSVNKKDLSICGSSGEEFFN--------------NCEVLQCGFSVPRENIRTR 471 ++ K + CG + N CE FS P T Sbjct: 863 HKVIHTGEKPYKCEE--CGKAFNWSSNLMEHKKIHTGETPYKCEECDKAFSWPSS--LTE 918 Query: 472 HKIC-------PCDKCEKVFPSISKLKRHYLIHTGQRPFGCNICGKSFRQSAHLKRHEQT 524 HK C++C K F S+L H H G+ P+ C CGK+F S++L H++ Sbjct: 919 HKATHAGEKPYKCEECGKAFSWPSRLTEHKATHAGEEPYKCEECGKAFNWSSNLMEHKRI 978 Query: 525 HNEKSPY-ASLCQVEFGNFNNLSNHSGNNVNYNASQQCQAPGVQKYEVSESDQMSGVKAE 583 H + PY C F F+ L+ H + +C+ G S + Sbjct: 979 HTGEKPYKCEECGKSFSTFSILTKHKVIHTG-EKPYKCEECGKAYKWSSTLSYHKKIHTV 1037 Query: 584 SQDFIPGSTGQPCLPNVLLESEQSNPFCSYSEHQEKNDVFLYRCSVCAKSFRSPSKLERH 643 + + G+ + +L + EK LY+C C K+++ PS L H Sbjct: 1038 EKPYKCEECGKGFVMFSILAKHK------VIHTGEK----LYKCEECGKAYKWPSTLRYH 1087 Query: 644 YLIHAGQKPFECSVCGKTFRQAPHWKRHQLTHFKERP 680 IH G+KP++C CGK F +H++ H E+P Sbjct: 1088 KKIHTGEKPYKCEECGKAFSTFSILTKHKVIHTGEKP 1124 Score = 191 bits (486), Expect = 1e-48 Identities = 166/668 (24%), Positives = 272/668 (40%), Gaps = 100/668 (14%) Query: 25 RPYVCNICFKHFETPSKLARHYLIHTGQKPFECDVCHKTFRQLVHLERHQLTHS--LPFK 82 +PY C C K F S L +H +IHTG+KP++C+ C K F +L H+ H+ P+K Sbjct: 563 KPYKCKECGKAFSKFSILTKHKVIHTGEKPYKCEECGKAFNWSSNLMEHKRIHTGEKPYK 622 Query: 83 CSICQRHFKNLKTFVKHQQLHNETYQNNVKQVRRLLEAKQEKSMYGVYNTFTTEERWALH 142 C C + F KH+ +H ++ + + S + +T E+ + Sbjct: 623 CEECGKSFSTFSVLTKHKVIHTGEKPYKCEECGKAYKWSSTLSYHKKIHT--VEKPYKCE 680 Query: 143 PCSKS-DPMYSMKRRKNIHA------CTICGKMFPSQSKLDRHVLIHTGQRPFKCVLCTK 195 C K+ + + + K IH C CGK F S L H IH G++P+KC C K Sbjct: 681 ECGKAFNRSAILIKHKRIHTDEKPYKCEECGKTFSKVSTLTTHKAIHAGEKPYKCKECGK 740 Query: 196 SFRQSTHLKIHQLTHSEERPFQCCFCQKGFKIQSKLLKHKQIHTRNKAFRALLLKKRRTE 255 +F + + L H++ H+ E+P++C C K +K S L HK+IHT K Sbjct: 741 AFSKFSILTKHKVIHTGEKPYKCEECGKAYKWPSTLSYHKKIHTGEK------------- 787 Query: 256 SRPLPNKLNANQGGFENGEIGESEENNPLDVHSIYIVPFQCPKCEKCFESEQILNEHS-C 314 P K GF I E V P++C +C K F + ++H Sbjct: 788 ----PYKCEECGKGFSMFSILTKHE-----VIHTGEKPYKCEECGKAFSWLSVFSKHKKT 838 Query: 315 FAARSGKIPSRFKRSYNYKTIVKKILAKLKRARSKKLDNFQSEKKV-FKKSFLRNCDLIS 373 A ++YN +I+ K K+ K + K + + + + + + Sbjct: 839 HAGEKFYKCEACGKAYNTFSILTK--HKVIHTGEKPYKCEECGKAFNWSSNLMEHKKIHT 896 Query: 374 GEQ--SSEQTQRTFV--GSLGKH-GTYKTIGNRKKKTLTLPFSWQNMGKNLKGILTTENI 428 GE E+ + F SL +H T+ K + FSW + LT Sbjct: 897 GETPYKCEECDKAFSWPSSLTEHKATHAGEKPYKCEECGKAFSWPSR-------LTEHKA 949 Query: 429 LSIDNSVNKKDLSICGSSGEEFFNNCEVLQCGFSVPRENIRTRHKICPCDKCEKVFPSIS 488 K C G+ F + +++ + I T K C++C K F + S Sbjct: 950 THAGEEPYK-----CEECGKAFNWSSNLME------HKRIHTGEKPYKCEECGKSFSTFS 998 Query: 489 KLKRHYLIHTGQRPFGCNICGKSFRQSAHLKRHEQTHNEKSPY-ASLCQVEFGNFNNLSN 547 L +H +IHTG++P+ C CGK+++ S+ L H++ H + PY C F F+ L+ Sbjct: 999 ILTKHKVIHTGEKPYKCEECGKAYKWSSTLSYHKKIHTVEKPYKCEECGKGFVMFSILAK 1058 Query: 548 HSGNNVNYNASQQCQAPGVQKYEVSESDQMSGVKAESQDFIPGSTGQPCLPNVLLESEQS 607 H + G + Y+ E + + + TG+ Sbjct: 1059 HKVIHT-----------GEKLYKCEECGKAYKWPSTLRYHKKIHTGE------------- 1094 Query: 608 NPFCSYSEHQEKNDVFLYRCSVCAKSFRSPSKLERHYLIHAGQKPFECSVCGKTFRQAPH 667 P+ +C C K+F + S L +H +IH G+KP++C CGK F Sbjct: 1095 KPY---------------KCEECGKAFSTFSILTKHKVIHTGEKPYKCEECGKAFSWLSV 1139 Query: 668 WKRHQLTH 675 + +H+ H Sbjct: 1140 FSKHKKIH 1147 Score = 147 bits (372), Expect = 2e-35 Identities = 130/544 (23%), Positives = 228/544 (41%), Gaps = 55/544 (10%) Query: 156 RKNIHACTICGKMFPSQSKLDRHVLIHTGQRPFKCVLCTKSFRQSTHLKIHQLTHSEERP 215 R+N + C GK F S L + HTG++P++C C K+F + + L H++ H+ E+ Sbjct: 197 RENSYKCEEGGKAFNWSSTLTYYKSAHTGEKPYRCKECGKAFSKFSILTKHKVIHTGEKS 256 Query: 216 FQCCFCQKGFKIQSKLLKHKQIHTRNKAFRALLLKKRRTESRPLP--NKLNANQGGFENG 273 ++C C K F + L KHK IHT K + K ++ L ++A + ++ Sbjct: 257 YKCEECGKAFNQSAILTKHKIIHTGEKPNKCEECGKAFSKVSTLTTHKAIHAGEKPYKCK 316 Query: 274 EIGES-EENNPLDVHSIYIV---PFQCPKCEKCFESEQILNEHSCFAARSGKIPSRFK-- 327 E G++ + + L H P++C +C K F IL +H +G+ P + + Sbjct: 317 ECGKAFSKVSTLITHKAIHAGEKPYKCKECGKAFSKFSILTKHK--VIHTGEKPYKCEEC 374 Query: 328 -RSYNYKTIV---KKILAKLKRARSKKLDNFQSEKKVFKKSFLRNCDLISGEQ--SSEQT 381 ++Y + + + KKI K + ++ S + K + + +GE+ E+ Sbjct: 375 GKAYKWPSTLSYHKKIHTGEKPYKCEECGKGFSMFSILTKHEV----IHTGEKPYKCEEC 430 Query: 382 QRTFVGSLGKHGTYKTIGNRKKKTLTLPFSWQNMGKNLKGILTTENILSIDNSVNKKDLS 441 + F + + + ++K T P+ + GK T I Sbjct: 431 GKAF------NWSSNLMEHKKIHTGETPYKCEECGKGFSWSSTLSYHKKIHTVEKPYKCE 484 Query: 442 ICGSSGEEFFNNCEVLQCGFSVPRENIRTRHKICPCDKCEKVFPSISKLKRHYLIHTGQR 501 CG + FN +L + + I T K C++C K F +S L H IH G++ Sbjct: 485 ECGKA----FNQSAIL-----IKHKRIHTGEKPYKCEECGKTFSKVSTLTTHKAIHAGEK 535 Query: 502 PFGCNICGKSFRQSAHLKRHEQTHNEKSPY-ASLCQVEFGNFNNLSNHSGNNVNYNASQQ 560 P+ C CGK+F + + L H+ H + PY C F F+ L+ H + + Sbjct: 536 PYKCKECGKTFIKVSTLTTHKAIHAGEKPYKCKECGKAFSKFSILTKHKVIHTG-EKPYK 594 Query: 561 CQAPGVQKYEVSESDQMSGVKAESQDFIPGSTGQPCLPNVLLESEQSNPFCSYSEHQEKN 620 C+ E ++ S E + G C E F ++S + Sbjct: 595 CE-------ECGKAFNWSSNLMEHKRIHTGEKPYKC-------EECGKSFSTFSVLTKHK 640 Query: 621 DVFL----YRCSVCAKSFRSPSKLERHYLIHAGQKPFECSVCGKTFRQAPHWKRHQLTHF 676 + Y+C C K+++ S L H IH +KP++C CGK F ++ +H+ H Sbjct: 641 VIHTGEKPYKCEECGKAYKWSSTLSYHKKIHTVEKPYKCEECGKAFNRSAILIKHKRIHT 700 Query: 677 KERP 680 E+P Sbjct: 701 DEKP 704 Score = 147 bits (370), Expect = 4e-35 Identities = 130/540 (24%), Positives = 229/540 (42%), Gaps = 74/540 (13%) Query: 25 RPYVCNICFKHFETPSKLARHYLIHTGQKPFECDVCHKTFRQLVHLERHQLTHSL--PFK 82 +PY C C K F T S L +H +IHTG+KP++C+ C K ++ L H+ H++ P+K Sbjct: 619 KPYKCEECGKSFSTFSVLTKHKVIHTGEKPYKCEECGKAYKWSSTLSYHKKIHTVEKPYK 678 Query: 83 CSICQRHFKNLKTFVKHQQLHNETYQNNVKQVRRLLEAKQEKSMYGVYNTFTTEERWALH 142 C C + F +KH+++H + ++ + + + + E+ + Sbjct: 679 CEECGKAFNRSAILIKHKRIHTDEKPYKCEECGKTFSKVSTLTTHKAIHA--GEKPYKCK 736 Query: 143 PCSKSDPMYS-MKRRKNIHA------CTICGKMFPSQSKLDRHVLIHTGQRPFKCVLCTK 195 C K+ +S + + K IH C CGK + S L H IHTG++P+KC C K Sbjct: 737 ECGKAFSKFSILTKHKVIHTGEKPYKCEECGKAYKWPSTLSYHKKIHTGEKPYKCEECGK 796 Query: 196 SFRQSTHLKIHQLTHSEERPFQCCFCQKGFKIQSKLLKHKQIHTRNKAFRALLLKKRRTE 255 F + L H++ H+ E+P++C C K F S KHK+ H K ++ K Sbjct: 797 GFSMFSILTKHEVIHTGEKPYKCEECGKAFSWLSVFSKHKKTHAGEKFYKCEACGKAYNT 856 Query: 256 SRPLPNK--LNANQGGFENGEIGESEE--NNPLDVHSIYI--VPFQCPKCEKCFESEQIL 309 L ++ + ++ E G++ +N ++ I+ P++C +C+K F L Sbjct: 857 FSILTKHKVIHTGEKPYKCEECGKAFNWSSNLMEHKKIHTGETPYKCEECDKAFSWPSSL 916 Query: 310 NEHSCFAARSGKIPSRFKRSYNYKTIVKKILAKLKRARSKKLDNFQSEKKVFKKS--FLR 367 EH A +G+ P + + + ++ ++ + K F S + Sbjct: 917 TEHK--ATHAGEKPYKCEECGKAFSWPSRLTEHKATHAGEEPYKCEECGKAFNWSSNLME 974 Query: 368 NCDLISGEQ--SSEQTQRTF--VGSLGKHGT----------------YK---TIGNRKK- 403 + + +GE+ E+ ++F L KH YK T+ KK Sbjct: 975 HKRIHTGEKPYKCEECGKSFSTFSILTKHKVIHTGEKPYKCEECGKAYKWSSTLSYHKKI 1034 Query: 404 KTLTLPFSWQNMGKN--LKGILTTENILSIDNSVNKKDLSICGSS--------------- 446 T+ P+ + GK + IL ++ + K + CG + Sbjct: 1035 HTVEKPYKCEECGKGFVMFSILAKHKVIHTGEKLYKCEE--CGKAYKWPSTLRYHKKIHT 1092 Query: 447 GEEFFNNCEVLQCGFSVPRENIRTRHKIC-------PCDKCEKVFPSISKLKRHYLIHTG 499 GE+ + CE +CG + +I T+HK+ C++C K F +S +H IHTG Sbjct: 1093 GEKPYK-CE--ECGKAFSTFSILTKHKVIHTGEKPYKCEECGKAFSWLSVFSKHKKIHTG 1149 Score = 144 bits (362), Expect = 4e-34 Identities = 156/647 (24%), Positives = 250/647 (38%), Gaps = 97/647 (14%) Query: 69 HLERHQLTHSLPFKCSICQRHFKN----------------LKTFVK--HQQLHNETYQNN 110 +++RH++ P CS HF L+ + K H+ LH + N Sbjct: 64 NMKRHEMVEESPVICS----HFAQDLWPEQGIEDSFQKVILRRYEKCGHENLHLKIGYTN 119 Query: 111 VKQVRRLLEA--KQEKSMYGVYNTFTTEERWA--LHPCSKSDPMYSMKRRKNIHACTICG 166 V + + E K +S+ + ++A H CS S+ K C Sbjct: 120 VDECKVHKEGYNKLNQSLTTTQSKVFQRGKYANVFHKCSNSNRHKIRHTGKKHLQCKEYV 179 Query: 167 KMFPSQSKLDRHVLIHTGQRPFKCVLCTKSFRQSTHLKIHQLTHSEERPFQCCFCQKGFK 226 + F S L +H I+T + +KC K+F S+ L ++ H+ E+P++C C K F Sbjct: 180 RSFCMLSHLSQHKRIYTRENSYKCEEGGKAFNWSSTLTYYKSAHTGEKPYRCKECGKAFS 239 Query: 227 IQSKLLKHKQIHTRNKAFRALLLKKRRTESRPLPNKLNANQGGFENGEIGESEENNPLDV 286 S L KHK IHT K+++ K +S L + G Sbjct: 240 KFSILTKHKVIHTGEKSYKCEECGKAFNQSAILTKHKIIHTGE----------------- 282 Query: 287 HSIYIVPFQCPKCEKCFESEQILNEHSCFAARSGKIPSRFKR-SYNYKTIVKKILAKLKR 345 P +C +C K F L H A +G+ P + K + + I K Sbjct: 283 -----KPNKCEECGKAFSKVSTLTTHK--AIHAGEKPYKCKECGKAFSKVSTLITHKAIH 335 Query: 346 ARSKKLDNFQSEKKVFKKSFLRNCDLISGEQSSEQTQRTFVGSLGKHGTYK---TIGNRK 402 A K + K K S L +I + + + GK YK T+ K Sbjct: 336 AGEKPYKCKECGKAFSKFSILTKHKVIHTGEKPYKCE-----ECGK--AYKWPSTLSYHK 388 Query: 403 K-KTLTLPFSWQNMGK--NLKGILTTENILSIDNSVNKKDLSICGSSGEEFFNNCEVLQC 459 K T P+ + GK ++ ILT ++ K C G+ F + +++ Sbjct: 389 KIHTGEKPYKCEECGKGFSMFSILTKHEVIHTGEKPYK-----CEECGKAFNWSSNLME- 442 Query: 460 GFSVPRENIRTRHKICPCDKCEKVFPSISKLKRHYLIHTGQRPFGCNICGKSFRQSAHLK 519 + I T C++C K F S L H IHT ++P+ C CGK+F QSA L Sbjct: 443 -----HKKIHTGETPYKCEECGKGFSWSSTLSYHKKIHTVEKPYKCEECGKAFNQSAILI 497 Query: 520 RHEQTHNEKSPY-ASLCQVEFGNFNNLSNHSGNNVNYNASQQCQAPGVQKYEVSESDQMS 578 +H++ H + PY C F + L+ H + +C+ G +VS Sbjct: 498 KHKRIHTGEKPYKCEECGKTFSKVSTLTTHKAIHAG-EKPYKCKECGKTFIKVSTLTTHK 556 Query: 579 GVKAESQDFIPGSTGQPCLPNVLLESEQSNPFCSYSEHQ-----EKNDVFLYRCSVCAKS 633 + A + + G + + F ++H+ EK Y+C C K+ Sbjct: 557 AIHAGEKPYKCKECG-----------KAFSKFSILTKHKVIHTGEKP----YKCEECGKA 601 Query: 634 FRSPSKLERHYLIHAGQKPFECSVCGKTFRQAPHWKRHQLTHFKERP 680 F S L H IH G+KP++C CGK+F +H++ H E+P Sbjct: 602 FNWSSNLMEHKRIHTGEKPYKCEECGKSFSTFSVLTKHKVIHTGEKP 648 >gi|194018469 zinc finger protein 546 [Homo sapiens] Length = 836 Score = 214 bits (545), Expect = 2e-55 Identities = 174/683 (25%), Positives = 294/683 (43%), Gaps = 92/683 (13%) Query: 23 RNRPYVCNICFKHFETPSKLARHYLIHTGQKPFECDVCHKTFRQLVHLERHQLTHS--LP 80 R + Y C C K F S L +H IHTG++P++C C K F ++ L H H+ P Sbjct: 213 REKSYECKECRKAFRQQSYLIQHLRIHTGERPYKCMECGKAFCRVGDLRVHHTIHAGERP 272 Query: 81 FKCSICQRHFKNLKTFVKHQQLHNETYQNNVKQVRRLLEAKQEKSMYGVYNTFTTEER-W 139 ++C C + F+ +HQ++H+ K+ + ++ V+ T ER + Sbjct: 273 YECKECGKAFRLHYHLTEHQRIHSGVKPYECKECGKAFSRVRDLR---VHQTIHAGERPY 329 Query: 140 ALHPCSKSDPM-YSMKRRKNIHA------CTICGKMFPSQSKLDRHVLIHTGQRPFKCVL 192 C K+ + Y + + IH C +CGK F Q + +H IHTG +P+KC Sbjct: 330 ECKECGKAFRLHYQLTEHQRIHTGERPYECKVCGKTFRVQRHISQHQKIHTGVKPYKCNE 389 Query: 193 CTKSFRQSTHLKIHQLTHSEERPFQCCFCQKGFKIQSKLLKHKQIHTRNKAFRALLLKK- 251 C K+F ++L HQ H+ E+P++C C K F ++L +H++IHT K + K Sbjct: 390 CGKAFSHGSYLVQHQKIHTGEKPYECKECGKSFSFHAELARHRRIHTGEKPYECRECGKA 449 Query: 252 -RRTESRPLPNKLNANQGGFENGEIGES-----EENNPLDVHSIYIVPFQCPKCEKCFES 305 R ++ + + +E E G++ + L H+ I P++C +C K F S Sbjct: 450 FRLQTELTRHHRTHTGEKPYECKECGKAFICGYQLTLHLRTHTGEI-PYECKECGKTFSS 508 Query: 306 EQILNEHSCFAARSGKIPSRFKRSYNYKTIVKKILAKLKRARSKKLDNFQS--EKKVFKK 363 L +H + +G+ P Y K + + R ++ + E K K Sbjct: 509 RYHLTQH--YRIHTGEKP------YICNECGKAFRLQGELTRHHRIHTCEKPYECKECGK 560 Query: 364 SFLRNCDLISGEQSSEQTQRTFVGSLGKHGTYKTIGNRKKKTLTLPFSWQNMGKNLKGIL 423 +F+ + IS ++ GK I +R+ N+ ++ K I Sbjct: 561 AFIHSNQFISHQRIHTSESTYICKECGK------IFSRR----------YNLTQHFK-IH 603 Query: 424 TTENILSIDNSVNKKDLSICGSSGEEFFNNCEVLQCGFSVPRENIRTRHKICPCDKCEKV 483 T E IC G+ F E+ Q I T K C +C K Sbjct: 604 TGEKPY------------ICNECGKAFRFQTELTQ------HHRIHTGEKPYKCTECGKA 645 Query: 484 FPSISKLKRHYLIHTGQRPFGCNICGKSFRQSAHLKRHEQTHNEKSPY-------ASLCQ 536 F + L +H+ IHTG++P+ C CGK+F + HL +H + H + PY A +C Sbjct: 646 FIRSTHLTQHHRIHTGEKPYECTECGKTFSRHYHLTQHHRGHTGEKPYICNECGNAFICS 705 Query: 537 VEFGNFNNLSNHSGNNVNYNASQQCQAPGVQKYEVSESDQM-SGVKAESQDFIPGSTGQP 595 + H+G + Y ++C ++Y +++ ++ +G K S + Sbjct: 706 YRLTLHQRI--HTG-ELPYEC-KECGKTFSRRYHLTQHFRLHTGEKPYS--------CKE 753 Query: 596 CLPNVLLESEQSNPFCSYSEHQEKNDVFLYRCSVCAKSFRSPSKLERHYLIHAGQKPFEC 655 C L++E + ++ + Y+C C K+F S+L RH+ IH G+KP++C Sbjct: 754 CGNAFRLQAELTRHHIVHTGEKP------YKCKECGKAFSVNSELTRHHRIHTGEKPYQC 807 Query: 656 SVCGKTFRQAPHWKRHQLTHFKE 678 CGK F ++ HQ H E Sbjct: 808 KECGKAFIRSDQLTLHQRNHISE 830 Score = 186 bits (471), Expect = 8e-47 Identities = 170/655 (25%), Positives = 259/655 (39%), Gaps = 104/655 (15%) Query: 45 HYLIHTGQKPFECDVCHKTFRQLVHLERHQLTHS--LPFKCSICQRHFKNLKTFVKHQQL 102 H IH +K +EC C K FRQ +L +H H+ P+KC C + F + H + Sbjct: 207 HPKIHAREKSYECKECRKAFRQQSYLIQHLRIHTGERPYKCMECGKAFCRVGDLRVHHTI 266 Query: 103 HNETYQNNVKQVRRLLEAKQEKSMYGVYNTFTTEERWALHPCSKSDPMYSMKRRKNIHAC 162 H R E K+ + ++ T +R +H K + C Sbjct: 267 HAG---------ERPYECKECGKAFRLHYHLTEHQR--IHSGVKP------------YEC 303 Query: 163 TICGKMFPSQSKLDRHVLIHTGQRPFKCVLCTKSFRQSTHLKIHQLTHSEERPFQCCFCQ 222 CGK F L H IH G+RP++C C K+FR L HQ H+ ERP++C C Sbjct: 304 KECGKAFSRVRDLRVHQTIHAGERPYECKECGKAFRLHYQLTEHQRIHTGERPYECKVCG 363 Query: 223 KGFKIQSKLLKHKQIHTRNKAFRALLLKKRRTESRPLPN--KLNANQGGFENGEIGES-- 278 K F++Q + +H++IHT K ++ K + L K++ + +E E G+S Sbjct: 364 KTFRVQRHISQHQKIHTGVKPYKCNECGKAFSHGSYLVQHQKIHTGEKPYECKECGKSFS 423 Query: 279 ---EENNPLDVHSIYIVPFQCPKCEKCFESEQILNEHSCFAARSGKIPSRFKRSYNYKTI 335 E +H+ P++C +C K F + L H +G+ P Y K Sbjct: 424 FHAELARHRRIHTGE-KPYECRECGKAFRLQTELTRHH--RTHTGEKP------YECKEC 474 Query: 336 VKKILA--KLKRARSKKLDNFQSEKKVFKKSFLRNCDLISGEQSSEQTQRTFVGSLGKHG 393 K + +L E K K+F S Q R G Sbjct: 475 GKAFICGYQLTLHLRTHTGEIPYECKECGKTF-------SSRYHLTQHYRIHTGEK---- 523 Query: 394 TYKTIGNRKKKTLTLPFSWQNMGK--NLKGILTTENILSIDNSVNKKDLSICGSSGEEFF 451 P+ GK L+G LT + + + C G+ F Sbjct: 524 ---------------PYICNECGKAFRLQGELTRHHRIHTCEKPYE-----CKECGKAFI 563 Query: 452 NNCEVLQCGFSVPRENIRTRHKICPCDKCEKVFPSISKLKRHYLIHTGQRPFGCNICGKS 511 ++ + + + I T C +C K+F L +H+ IHTG++P+ CN CGK+ Sbjct: 564 HSNQFIS------HQRIHTSESTYICKECGKIFSRRYNLTQHFKIHTGEKPYICNECGKA 617 Query: 512 FRQSAHLKRHEQTHNEKSPY-ASLCQVEFGNFNNLSNHSGNNVNYNASQQCQAPGVQKYE 570 FR L +H + H + PY + C F +L+ H + G + YE Sbjct: 618 FRFQTELTQHHRIHTGEKPYKCTECGKAFIRSTHLTQHHRIHT-----------GEKPYE 666 Query: 571 VSESDQMSGVKAESQDFIPGSTGQ-PCLPNVLLESEQSNPF-CSY--SEHQEKNDVFL-Y 625 +E + G TG+ P + N E N F CSY + HQ + L Y Sbjct: 667 CTECGKTFSRHYHLTQHHRGHTGEKPYICN-----ECGNAFICSYRLTLHQRIHTGELPY 721 Query: 626 RCSVCAKSFRSPSKLERHYLIHAGQKPFECSVCGKTFRQAPHWKRHQLTHFKERP 680 C C K+F L +H+ +H G+KP+ C CG FR RH + H E+P Sbjct: 722 ECKECGKTFSRRYHLTQHFRLHTGEKPYSCKECGNAFRLQAELTRHHIVHTGEKP 776 Score = 180 bits (456), Expect = 4e-45 Identities = 156/621 (25%), Positives = 259/621 (41%), Gaps = 99/621 (15%) Query: 70 LERHQLTHSLPFKCSICQRHFKNLKTFVKHQQ-LHNETYQNNVKQVRRLLEAKQEKSMYG 128 LE +T +L + ++C+ + L+T K + +H +T N Q + E +QE+ G Sbjct: 133 LEYKYITKNLLSEKNVCKIYLSQLQTGEKSKNTIHEDTIFRNGLQCKHEFE-RQERHQMG 191 Query: 129 VYNTFTTEERWA--LHPCSKSDPMYSMKRRKNIHACTICGKMFPSQSKLDRHVLIHTGQR 186 + +++ + LHP + R+ + C C K F QS L +H+ IHTG+R Sbjct: 192 CVSQMLIQKQISHPLHP--------KIHAREKSYECKECRKAFRQQSYLIQHLRIHTGER 243 Query: 187 PFKCVLCTKSFRQSTHLKIHQLTHSEERPFQCCFCQKGFKIQSKLLKHKQIHTRNKAFRA 246 P+KC+ C K+F + L++H H+ ERP++C C K F++ L +H++IH+ K + Sbjct: 244 PYKCMECGKAFCRVGDLRVHHTIHAGERPYECKECGKAFRLHYHLTEHQRIHSGVKPYEC 303 Query: 247 LLLKKRRTESRPLPNKLNANQGGFENGEIGESEENNPLDVHSIYIVPFQCPKCEKCFESE 306 K + R L + G P++C +C K F Sbjct: 304 KECGKAFSRVRDLRVHQTIHAGER----------------------PYECKECGKAFRLH 341 Query: 307 QILNEHSCFAARSGKIPSRFKRSYNYKTIVKKILAKLKRARSKKLDNFQSEKKVFK--KS 364 L EH +G+ P Y K K + ++ +K+ K + K+ Sbjct: 342 YQLTEHQ--RIHTGERP------YECKVCGKTFRVQRHISQHQKIHTGVKPYKCNECGKA 393 Query: 365 FLRNCDLISGEQSSEQTQRTFVGSLGKHGTY--KTIGNRKKKTLTLPFSWQNMGKNLKGI 422 F L+ ++ + GK ++ + +R+ T P+ + GK + Sbjct: 394 FSHGSYLVQHQKIHTGEKPYECKECGKSFSFHAELARHRRIHTGEKPYECRECGKAFR-- 451 Query: 423 LTTENILSIDNSVNKKDLSICGSSGEEFFNNCEVLQCGFSVPRENIRTRHKICP--CDKC 480 L TE +K C G+ F CG+ + ++RT P C +C Sbjct: 452 LQTELTRHHRTHTGEKPYE-CKECGKAFI-------CGYQLTL-HLRTHTGEIPYECKEC 502 Query: 481 EKVFPSISKLKRHYLIHTGQRPFGCNICGKSFRQSAHLKRHEQTHNEKSPY-ASLCQVEF 539 K F S L +HY IHTG++P+ CN CGK+FR L RH + H + PY C F Sbjct: 503 GKTFSSRYHLTQHYRIHTGEKPYICNECGKAFRLQGELTRHHRIHTCEKPYECKECGKAF 562 Query: 540 GNFNNLSNHSGNNVNYNASQQCQAPGVQKYEVSESDQMSGVKAESQDFIPGSTGQPCLPN 599 + N +H Q+ SES + C Sbjct: 563 IHSNQFISH------------------QRIHTSESTYI------------------CKEC 586 Query: 600 VLLESEQSNPFCSYSEHQEKNDVFLYRCSVCAKSFRSPSKLERHYLIHAGQKPFECSVCG 659 + S + N + H + Y C+ C K+FR ++L +H+ IH G+KP++C+ CG Sbjct: 587 GKIFSRRYNLTQHFKIHTGEKP---YICNECGKAFRFQTELTQHHRIHTGEKPYKCTECG 643 Query: 660 KTFRQAPHWKRHQLTHFKERP 680 K F ++ H +H H E+P Sbjct: 644 KAFIRSTHLTQHHRIHTGEKP 664 >gi|157167158 zinc finger protein 808 [Homo sapiens] Length = 903 Score = 214 bits (544), Expect = 3e-55 Identities = 172/677 (25%), Positives = 272/677 (40%), Gaps = 136/677 (20%) Query: 25 RPYVCNICFKHFETPSKLARHYLIHTGQKPFECDVCHKTFRQLVHLERHQLTHS--LPFK 82 +PY CN C K F S L H IHTG+KP++C+ C K F Q HL RHQ H+ P+K Sbjct: 313 KPYKCNECGKVFRQNSALVIHKAIHTGEKPYKCNECGKAFNQQSHLSRHQRLHTGVKPYK 372 Query: 83 CSICQRHFKNLKTFVKHQQLHNETYQNNVKQVRRLLEAKQEKSMYGVYNTFTTEERWALH 142 C IC+ K F H L N T +H Sbjct: 373 CKICE------KAFACHSYLANHT---------------------------------RIH 393 Query: 143 PCSKSDPMYSMKRRKNIHACTICGKMFPSQSKLDRHVLIHTGQRPFKCVLCTKSFRQSTH 202 K+ + C CGK F QS L RH ++HTG++P+KC C K F Q + Sbjct: 394 SGEKT------------YKCNECGKAFNHQSSLARHHILHTGEKPYKCEECDKVFSQKST 441 Query: 203 LKIHQLTHSEERPFQCCFCQKGFKIQSKLLKHKQIHTRNKAFRALLLKK--RRTESRPLP 260 L+ H+ H+ E+P++C C F S+L +H++IHT K ++ +K R S Sbjct: 442 LERHKRIHTGEKPYKCKVCDTAFTCNSQLARHRRIHTGEKTYKCNECRKTFSRRSSLLCH 501 Query: 261 NKLNANQGGFENGEIGESEENNPLDVHSIYI----VPFQCPKCEKCFESEQILNEHSCFA 316 +L++ + ++ + G + + V+ + ++C C K F +L H+ Sbjct: 502 RRLHSGEKPYKCNQCGNTFRHRASLVYHRRLHTLEKSYKCTVCNKVFMRNSVLAVHTRIH 561 Query: 317 ARSGKIPSRFKRSYNYKTIVKKILAKLKRARSKKLDNFQSEKKVFKKSFLRNCDLISGEQ 376 K+ Y K + +R ++L + K CD + G++ Sbjct: 562 TA--------KKPYKCNECGKAFNQQSHLSRHRRLHTGEKPYK------CEACDKVFGQK 607 Query: 377 SSEQTQRTFVGSLGKHGTYKTIGNRKKKTLTLPFSWQNMGKNLKGILTTENILSIDNSVN 436 S+ ++ + H K + + F+W + I T E + Sbjct: 608 SALESHKRI------HTGEKPY---RCQVCDTAFTWNSQLARHTRIHTGEKTYKCNEC-- 656 Query: 437 KKDLSICGS-------SGEEFFNNCEVLQCGF-----SVPRENIRTRHKICPCDKCEKVF 484 K S S G E C+V F I + K C++C K F Sbjct: 657 GKTFSYKSSLVWHRRLHGGEKSYKCKVCDKAFVCRSYVAKHTRIHSGMKPYKCNECSKTF 716 Query: 485 PSISKLKRHYLIHTGQRPFGCNICGKSFRQSAHLKRHEQTHNEKSPY-ASLCQVEFGNFN 543 + S L H IH+G++P+ C+ C K+F Q A L H + H+ + PY + C F +++ Sbjct: 717 SNRSSLVCHRRIHSGEKPYKCSECSKTFSQKATLLCHRRLHSGEKPYKCNDCGNTFRHWS 776 Query: 544 NLSNHSGNNVNYNASQQCQAPGVQKYEVSESDQMSGVKAESQDFIPGSTGQPCLPNVLLE 603 +L H + G + Y+ + D+ F+ S L + Sbjct: 777 SLVYHRRLHT-----------GEKSYKCTVCDKA---------FVRNS----YLARHIRI 812 Query: 604 SEQSNPFCSYSEHQEKNDVFLYRCSVCAKSFRSPSKLERHYLIHAGQKPFECSVCGKTFR 663 P Y+C+ C K+F S L RH+ IH G+KP++C C K F Sbjct: 813 HTAEKP---------------YKCNECGKAFNEQSHLSRHHRIHTGEKPYKCEACDKVFS 857 Query: 664 QAPHWKRHQLTHFKERP 680 + H KRH++ H E+P Sbjct: 858 RKSHLKRHRIIHTGEKP 874 Score = 188 bits (477), Expect = 2e-47 Identities = 134/538 (24%), Positives = 224/538 (41%), Gaps = 55/538 (10%) Query: 25 RPYVCNICFKHFETPSKLARHYLIHTGQKPFECDVCHKTFRQLVHLERHQLTHS--LPFK 82 + Y CN C K F S LARH+++HTG+KP++C+ C K F Q LERH+ H+ P+K Sbjct: 397 KTYKCNECGKAFNHQSSLARHHILHTGEKPYKCEECDKVFSQKSTLERHKRIHTGEKPYK 456 Query: 83 CSICQRHFKNLKTFVKHQQLHNETYQNNVKQVRRLLEAKQEKSMYGVYNTFTTEERWALH 142 C +C F +H+++H + R+ + S+ + E+ + + Sbjct: 457 CKVCDTAFTCNSQLARHRRIHTGEKTYKCNECRKTFSRRS--SLLCHRRLHSGEKPYKCN 514 Query: 143 PCSKS-DPMYSMKRRKNIHA------CTICGKMFPSQSKLDRHVLIHTGQRPFKCVLCTK 195 C + S+ + +H CT+C K+F S L H IHT ++P+KC C K Sbjct: 515 QCGNTFRHRASLVYHRRLHTLEKSYKCTVCNKVFMRNSVLAVHTRIHTAKKPYKCNECGK 574 Query: 196 SFRQSTHLKIHQLTHSEERPFQCCFCQKGFKIQSKLLKHKQIHTRNKAFRALLLKKRRTE 255 +F Q +HL H+ H+ E+P++C C K F +S L HK+IHT K +R + T Sbjct: 575 AFNQQSHLSRHRRLHTGEKPYKCEACDKVFGQKSALESHKRIHTGEKPYRCQVCDTAFTW 634 Query: 256 SRPLPNKLNANQGGFENGEIGESEENNPLDVHSIYIVPFQCPKCEKCFESEQILNEHSCF 315 + L + G ++C +C K F + L H Sbjct: 635 NSQLARHTRIHTGE----------------------KTYKCNECGKTFSYKSSLVWHRRL 672 Query: 316 AARSGKIPSRFKRSYNYKTIVKKILAKLKRARSKKLDNFQSEKKVFK--KSFLRNCDLIS 373 ++SY K K + + A+ ++ + K + K+F L+ Sbjct: 673 HGG--------EKSYKCKVCDKAFVCRSYVAKHTRIHSGMKPYKCNECSKTFSNRSSLVC 724 Query: 374 GEQSSEQTQRTFVGSLGKHGTYKT--IGNRKKKTLTLPFSWQNMGKNLKGILTTENILSI 431 + + K + K + +R+ + P+ + G + + + Sbjct: 725 HRRIHSGEKPYKCSECSKTFSQKATLLCHRRLHSGEKPYKCNDCGNTFRHWSSLVYHRRL 784 Query: 432 DNSVNKKDLSICGSSGEEFFNNCEVLQCGFSVPRENIRTRHKICPCDKCEKVFPSISKLK 491 ++C + F N + I T K C++C K F S L Sbjct: 785 HTGEKSYKCTVCDKA---FVRN------SYLARHIRIHTAEKPYKCNECGKAFNEQSHLS 835 Query: 492 RHYLIHTGQRPFGCNICGKSFRQSAHLKRHEQTHNEKSPY-ASLCQVEFGNFNNLSNH 548 RH+ IHTG++P+ C C K F + +HLKRH H + PY + C F + + L +H Sbjct: 836 RHHRIHTGEKPYKCEACDKVFSRKSHLKRHRIIHTGEKPYKCNECGKAFSDRSTLIHH 893 Score = 182 bits (462), Expect = 9e-46 Identities = 160/652 (24%), Positives = 262/652 (40%), Gaps = 90/652 (13%) Query: 40 SKLARHYLIHTGQKPFECDVCHKTFRQLVHLERHQLTH--SLPFKCSICQRHFKNLKTFV 97 S L + +H +K F C+ K F L +HQ+ H +KC +C + F + + Sbjct: 216 SLLPQKQEVHMREKSFPCNESGKAFNCSSLLRKHQIPHLGDKQYKCDVCGKLFNHKQYLA 275 Query: 98 KHQQLHNETYQNNVKQVRRLLEAKQEKSMYGVYNTFTTEERWALHPCSKSDPMYSMKRRK 157 H++ H K+ + K ++ T R LH K Sbjct: 276 CHRRCHTGEKPYKCKECGKSFSYK---------SSLTCHHR--LHTGVKP---------- 314 Query: 158 NIHACTICGKMFPSQSKLDRHVLIHTGQRPFKCVLCTKSFRQSTHLKIHQLTHSEERPFQ 217 + C CGK+F S L H IHTG++P+KC C K+F Q +HL HQ H+ +P++ Sbjct: 315 --YKCNECGKVFRQNSALVIHKAIHTGEKPYKCNECGKAFNQQSHLSRHQRLHTGVKPYK 372 Query: 218 CCFCQKGFKIQSKLLKHKQIHTRNKAFRALLLKKRRTESRPLPNKLNANQGGFENGEIGE 277 C C+K F S L H +IH+ K ++ K L A GE Sbjct: 373 CKICEKAFACHSYLANHTRIHSGEKTYKCNECGKAFNHQSSL-----ARHHILHTGE--- 424 Query: 278 SEENNPLDVHSIYIVPFQCPKCEKCFESEQILNEHSCFAARSGKIPSRFKRSYNYKTIVK 337 P++C +C+K F + L H +G+ P + K T Sbjct: 425 --------------KPYKCEECDKVFSQKSTLERHK--RIHTGEKPYKCKVCDTAFTCNS 468 Query: 338 KILAKLKRARSKKLDNFQSEKKVFKK--SFLRNCDLISGEQSSEQTQRTFVGSLGKHGTY 395 ++ + +K +K F + S L + L SGE+ + Q G+ +H Sbjct: 469 QLARHRRIHTGEKTYKCNECRKTFSRRSSLLCHRRLHSGEKPYKCNQ---CGNTFRHRA- 524 Query: 396 KTIGNRKKKTLTLPFSWQNMGKNLKGILTTENILSIDNSVNK-KDLSICGSSGEEFFNNC 454 + +R+ TL + K + ++L++ ++ K C G+ F Sbjct: 525 SLVYHRRLHTLEKSYKCTVCNK----VFMRNSVLAVHTRIHTAKKPYKCNECGKAFNQQS 580 Query: 455 EVLQCGFSVPRENIRTRHKICPCDKCEKVFPSISKLKRHYLIHTGQRPFGCNICGKSFRQ 514 + + + T K C+ C+KVF S L+ H IHTG++P+ C +C +F Sbjct: 581 HLSR------HRRLHTGEKPYKCEACDKVFGQKSALESHKRIHTGEKPYRCQVCDTAFTW 634 Query: 515 SAHLKRHEQTH-NEKSPYASLCQVEFGNFNNLSNH---SGNNVNYNASQQCQAPGVQKYE 570 ++ L RH + H EK+ + C F ++L H G +Y +A + Y Sbjct: 635 NSQLARHTRIHTGEKTYKCNECGKTFSYKSSLVWHRRLHGGEKSYKCKVCDKAFVCRSYV 694 Query: 571 VSESDQMSGVKAESQDFIPGSTGQPCLPNVLLESEQSNPFCSYSEHQEKNDVFLYRCSVC 630 + SG+K C S +S+ C H + Y+CS C Sbjct: 695 AKHTRIHSGMKP-----------YKCNECSKTFSNRSSLVCHRRIHSGEKP---YKCSEC 740 Query: 631 AKSFRSPSKLERHYLIHAGQKPFECSVCGKTFRQAPHWKR---HQLTHFKER 679 +K+F + L H +H+G+KP++C+ CG TFR HW H+ H E+ Sbjct: 741 SKTFSQKATLLCHRRLHSGEKPYKCNDCGNTFR---HWSSLVYHRRLHTGEK 789 Score = 145 bits (365), Expect = 2e-34 Identities = 90/331 (27%), Positives = 154/331 (46%), Gaps = 31/331 (9%) Query: 11 KIQQCVVANKL--------------PRNRPYVCNICFKHFETPSKLARHYLIHTGQKPFE 56 K +C V NK+ +PY CN C K F S L+RH +HTG+KP++ Sbjct: 537 KSYKCTVCNKVFMRNSVLAVHTRIHTAKKPYKCNECGKAFNQQSHLSRHRRLHTGEKPYK 596 Query: 57 CDVCHKTFRQLVHLERHQLTHS--LPFKCSICQRHFKNLKTFVKHQQLHNETYQNNVKQV 114 C+ C K F Q LE H+ H+ P++C +C F +H ++H + Sbjct: 597 CEACDKVFGQKSALESHKRIHTGEKPYRCQVCDTAFTWNSQLARHTRIHTGEKTYKCNEC 656 Query: 115 RRLLEAKQEKSMYGVYNTFTTEERWALHPCSKSDPMYS-MKRRKNIHA------CTICGK 167 + K S+ E+ + C K+ S + + IH+ C C K Sbjct: 657 GKTFSYKS--SLVWHRRLHGGEKSYKCKVCDKAFVCRSYVAKHTRIHSGMKPYKCNECSK 714 Query: 168 MFPSQSKLDRHVLIHTGQRPFKCVLCTKSFRQSTHLKIHQLTHSEERPFQCCFCQKGFKI 227 F ++S L H IH+G++P+KC C+K+F Q L H+ HS E+P++C C F+ Sbjct: 715 TFSNRSSLVCHRRIHSGEKPYKCSECSKTFSQKATLLCHRRLHSGEKPYKCNDCGNTFRH 774 Query: 228 QSKLLKHKQIHTRNKAFRALLLKKRRTESRPLPN--KLNANQGGFENGEIGE--SEENNP 283 S L+ H+++HT K+++ + K + L +++ + ++ E G+ +E+++ Sbjct: 775 WSSLVYHRRLHTGEKSYKCTVCDKAFVRNSYLARHIRIHTAEKPYKCNECGKAFNEQSHL 834 Query: 284 LDVHSIYI--VPFQCPKCEKCFESEQILNEH 312 H I+ P++C C+K F + L H Sbjct: 835 SRHHRIHTGEKPYKCEACDKVFSRKSHLKRH 865 Score = 131 bits (329), Expect = 2e-30 Identities = 135/559 (24%), Positives = 226/559 (40%), Gaps = 57/559 (10%) Query: 156 RKNIHACTICGKMFPSQSKLDRHVLIHTGQRPFKCVLCTKSFRQSTHLKIHQLTHSEERP 215 R IH G + S L + +H ++ F C K+F S+ L+ HQ+ H ++ Sbjct: 199 RPQIHISNNYGNNPLNSSLLPQKQEVHMREKSFPCNESGKAFNCSSLLRKHQIPHLGDKQ 258 Query: 216 FQCCFCQKGFKIQSKLLKHKQIHTRNKAFRALLLKKRRTESRPLP--NKLNANQGGFENG 273 ++C C K F + L H++ HT K ++ K + L ++L+ ++ Sbjct: 259 YKCDVCGKLFNHKQYLACHRRCHTGEKPYKCKECGKSFSYKSSLTCHHRLHTGVKPYKCN 318 Query: 274 EIGE-SEENNPLDVHSIYIV---PFQCPKCEKCFESEQILNEHSCFAARSGKIPSRFKRS 329 E G+ +N+ L +H P++C +C K F + L+ H +G P Sbjct: 319 ECGKVFRQNSALVIHKAIHTGEKPYKCNECGKAFNQQSHLSRHQ--RLHTGVKP------ 370 Query: 330 YNYKTIVKKILAKLKRARSKKLDNFQSEKKV--------FKKSFLRNCDLISGEQ--SSE 379 Y K K A ++ + + K + S R+ L +GE+ E Sbjct: 371 YKCKICEKAFACHSYLANHTRIHSGEKTYKCNECGKAFNHQSSLARHHILHTGEKPYKCE 430 Query: 380 QTQRTF--VGSLGKHGTYKTIGNR--KKKTLTLPFSWQNMGKNLKGILTTENILSID--- 432 + + F +L +H T G + K K F+ + + I T E + Sbjct: 431 ECDKVFSQKSTLERHKRIHT-GEKPYKCKVCDTAFTCNSQLARHRRIHTGEKTYKCNECR 489 Query: 433 NSVNKKDLSICG---SSGEEFFNNCEVLQCGFS-------VPRENIRTRHKICPCDKCEK 482 + +++ +C SGE+ + C QCG + V + T K C C K Sbjct: 490 KTFSRRSSLLCHRRLHSGEKPY-KCN--QCGNTFRHRASLVYHRRLHTLEKSYKCTVCNK 546 Query: 483 VFPSISKLKRHYLIHTGQRPFGCNICGKSFRQSAHLKRHEQTHNEKSPY-ASLCQVEFGN 541 VF S L H IHT ++P+ CN CGK+F Q +HL RH + H + PY C FG Sbjct: 547 VFMRNSVLAVHTRIHTAKKPYKCNECGKAFNQQSHLSRHRRLHTGEKPYKCEACDKVFGQ 606 Query: 542 FNNLSNHSGNNVNYNASQQCQAPGVQKYEVSESDQMSGVKAESQDFIPGSTGQPCLPNVL 601 + L +H + +CQ S+ + + + + + G+ Sbjct: 607 KSALESHKRIHTG-EKPYRCQVCDTAFTWNSQLARHTRIHTGEKTYKCNECGK------T 659 Query: 602 LESEQSNPFCSYSEHQEKNDVFLYRCSVCAKSFRSPSKLERHYLIHAGQKPFECSVCGKT 661 + S + EK+ Y+C VC K+F S + +H IH+G KP++C+ C KT Sbjct: 660 FSYKSSLVWHRRLHGGEKS----YKCKVCDKAFVCRSYVAKHTRIHSGMKPYKCNECSKT 715 Query: 662 FRQAPHWKRHQLTHFKERP 680 F H+ H E+P Sbjct: 716 FSNRSSLVCHRRIHSGEKP 734 Score = 99.8 bits (247), Expect = 8e-21 Identities = 67/231 (29%), Positives = 105/231 (45%), Gaps = 27/231 (11%) Query: 468 IRTRHKICPCDKCEKVFPSISKLKRHYLIHTGQRPFGCNICGKSFRQSAHLKRHEQTHNE 527 I + K C++C K F S L RH+++HTG++P+ C C K F Q + L+RH++ H Sbjct: 392 IHSGEKTYKCNECGKAFNHQSSLARHHILHTGEKPYKCEECDKVFSQKSTLERHKRIHTG 451 Query: 528 KSPY-ASLCQVEFGNFNNLSNHSGNNVNYNASQQCQAPGVQKYEVSESDQMSGVKAE--- 583 + PY +C F + L+ H + G + Y+ +E + ++ Sbjct: 452 EKPYKCKVCDTAFTCNSQLARHRRIHT-----------GEKTYKCNECRKTFSRRSSLLC 500 Query: 584 SQDFIPGSTGQPCLPNVLLESEQSNPF---CSYSEHQEKNDVFL-YRCSVCAKSFRSPSK 639 + G C ++ N F S H+ + + Y+C+VC K F S Sbjct: 501 HRRLHSGEKPYKC-------NQCGNTFRHRASLVYHRRLHTLEKSYKCTVCNKVFMRNSV 553 Query: 640 LERHYLIHAGQKPFECSVCGKTFRQAPHWKRHQLTHFKERPQGKVVALDSV 690 L H IH +KP++C+ CGK F Q H RH+ H E+P K A D V Sbjct: 554 LAVHTRIHTAKKPYKCNECGKAFNQQSHLSRHRRLHTGEKPY-KCEACDKV 603 Score = 96.7 bits (239), Expect = 7e-20 Identities = 84/357 (23%), Positives = 147/357 (41%), Gaps = 39/357 (10%) Query: 343 LKRARSKKLDNF---QSEKKVFKKSFLRNCDLISGEQSSEQTQRTFVGSLGKHGTYKTIG 399 L+R +S + +F + EK++ F D +G ++ + GS +H ++ G Sbjct: 90 LQRHQSYHIGDFCFQEIEKEIHNIEFQCQEDERNGHEAPTTKIKKLTGSTDQHD-HRHAG 148 Query: 400 NRKKKTLTLPFSWQNMGK----NLKGILTT--ENILSIDNSVNKKDLSICGSS---GEEF 450 N+ K + ++ + +KG + E S +SV+ C + Sbjct: 149 NKPIKDQLGSSFYSHLPELHIFQIKGEIANQLEKSTSDASSVSTSQRISCRPQIHISNNY 208 Query: 451 FNNCEVLQCGFSVPRENIRTRHKICPCDKCEKVFPSISKLKRHYLIHTGQRPFGCNICGK 510 NN L ++ + R K PC++ K F S L++H + H G + + C++CGK Sbjct: 209 GNN--PLNSSLLPQKQEVHMREKSFPCNESGKAFNCSSLLRKHQIPHLGDKQYKCDVCGK 266 Query: 511 SFRQSAHLKRHEQTHNEKSPYASLCQVEFGNFNNLSNHSGNNVNYNASQQCQA---PGVQ 567 F +L H + H + PY G + +Y +S C GV+ Sbjct: 267 LFNHKQYLACHRRCHTGEKPYKC-------------KECGKSFSYKSSLTCHHRLHTGVK 313 Query: 568 KYEVSESDQM---SGVKAESQDFIPGSTGQPCLPNVLLESEQSNPFCSYSEHQEKND-VF 623 Y+ +E ++ + + G C ++QS+ S HQ + V Sbjct: 314 PYKCNECGKVFRQNSALVIHKAIHTGEKPYKCNECGKAFNQQSH----LSRHQRLHTGVK 369 Query: 624 LYRCSVCAKSFRSPSKLERHYLIHAGQKPFECSVCGKTFRQAPHWKRHQLTHFKERP 680 Y+C +C K+F S L H IH+G+K ++C+ CGK F RH + H E+P Sbjct: 370 PYKCKICEKAFACHSYLANHTRIHSGEKTYKCNECGKAFNHQSSLARHHILHTGEKP 426 Score = 56.6 bits (135), Expect = 7e-08 Identities = 24/55 (43%), Positives = 31/55 (56%) Query: 25 RPYVCNICFKHFETPSKLARHYLIHTGQKPFECDVCHKTFRQLVHLERHQLTHSL 79 +PY C C K F S L RH +IHTG+KP++C+ C K F L HQ H + Sbjct: 845 KPYKCEACDKVFSRKSHLKRHRIIHTGEKPYKCNECGKAFSDRSTLIHHQAIHGI 899 >gi|40217792 zinc finger protein 585A [Homo sapiens] Length = 714 Score = 209 bits (532), Expect = 7e-54 Identities = 178/670 (26%), Positives = 285/670 (42%), Gaps = 88/670 (13%) Query: 22 PRNRPYVCNICFKHFETPSKLARHYLIHTGQKPFECDVCHKTFRQLVHLERHQLTH--SL 79 P + Y C K F S+L H + G+K + C C K F Q HQ TH Sbjct: 70 PGEKAYECAKFEKIFTQKSQLKVHLKVLAGEKLYVCIECGKAFVQKPEFIIHQKTHMREK 129 Query: 80 PFKCSICQRHFKNLKTFVKHQQLHNETYQNNVKQVRRLLEAKQEKSMYGVYNTFTTEERW 139 PFKC+ C + F + + +HQ++H +L E Q + + + E+ Sbjct: 130 PFKCNECGKSFFQVSSLFRHQRIHTG---------EKLYECSQCGKGFSYNSDLSIHEK- 179 Query: 140 ALHPCSKSDPMYSMKRRKNIHACTICGKMFPSQSKLDRHVLIHTGQRPFKCVLCTKSFRQ 199 +++ +R H CT CGK F +S L H IHTG+R + C+ C ++F Q Sbjct: 180 ----------IHTGERH---HECTDCGKAFTQKSTLKMHQKIHTGERSYICIECGQAFIQ 226 Query: 200 STHLKIHQLTHSEERPFQCCFCQKGFKIQSKLLKHKQIHTRNKAFRALLLKKRRTESRPL 259 THL H+ H+ E+P++C C K F +S+L H+++HTR K + TE Sbjct: 227 KTHLIAHRRIHTGEKPYECSNCGKSFISKSQLQVHQRVHTRVKPYIC-------TEY--- 276 Query: 260 PNKLNANQGGFENGEIGESEENNPLDVHSIYIVPFQCPKCEKCF--ESEQILNEHSCFAA 317 K+ +N + +S E + + C +C K F SE I+++ Sbjct: 277 -GKVFSNNSNLVTHKKVQSREKSSI-----------CTECGKAFTYRSELIIHQR----I 320 Query: 318 RSGKIPSRFKRSYNYKTIVKKILAKLKRARSKKLDNFQSEKKVFK--KSFLRNCDLISGE 375 +G+ P Y K K +++ + K +F++ LI+ + Sbjct: 321 HTGEKP------YECSDCGKAFTQKSALTVHQRIHTGEKSYICMKCGLAFIQKAHLIAHQ 374 Query: 376 QSSEQTQRTFVGSLGKHGTYKTIGNRKKKTLT--LPFSWQNMGKNLKGILTTENILSIDN 433 + G GK T K+ + K+ T P+ GK N+++ Sbjct: 375 IIHTGEKPHKCGHCGKLFTSKSQLHVHKRIHTGEKPYMCNKCGK---AFTNRSNLITHQK 431 Query: 434 SVNKKDLSICGSSGEEFFNNCEVLQCGFSVPRENIRTRHKICPCDKCEKVFPSISKLKRH 493 + + IC G+ F ++ + + I T K C+ C K F S L H Sbjct: 432 THTGEKSYICSKCGKAFTQRSDL------ITHQRIHTGEKPYECNTCGKAFTQKSHLNIH 485 Query: 494 YLIHTGQRPFGCNICGKSFRQSAHLKRHEQTHNEKSPYASL-CQVEFGNFNNLSNHSGNN 552 IHTG+R + C+ CGK+F Q + L H++ H + PY C F +N H + Sbjct: 486 QKIHTGERQYECHECGKAFNQKSILIVHQKIHTGEKPYVCTECGRAFIRKSNFITHQRIH 545 Query: 553 VNYNASQQCQAPGVQKYEVSESDQMSGVKAESQDFIPGSTGQPCLPNVLLESEQS-NPFC 611 G + YE S+ + K++ P TG+ P V E ++ + Sbjct: 546 T-----------GEKPYECSDCGKSFTSKSQLLVHQPVHTGEK--PYVCAECGKAFSGRS 592 Query: 612 SYSEHQEKNDVFL-YRCSVCAKSFRSPSKLERHYLIHAGQKPFECSVCGKTFRQAPHWKR 670 + S+HQ+ + Y CS C K+FR S+L H+ IH G+KP+ECS CGK+F + + Sbjct: 593 NLSKHQKTHTGEKPYICSECGKTFRQKSELITHHRIHTGEKPYECSDCGKSFTKKSQLQV 652 Query: 671 HQLTHFKERP 680 HQ H E+P Sbjct: 653 HQRIHTGEKP 662 Score = 164 bits (415), Expect = 3e-40 Identities = 147/603 (24%), Positives = 244/603 (40%), Gaps = 89/603 (14%) Query: 23 RNRPYVCNICFKHFETPSKLARHYLIHTGQKPFECDVCHKTFRQLVHLERHQLTHS--LP 80 R +P+ CN C K F S L RH IHTG+K +EC C K F L H+ H+ Sbjct: 127 REKPFKCNECGKSFFQVSSLFRHQRIHTGEKLYECSQCGKGFSYNSDLSIHEKIHTGERH 186 Query: 81 FKCSICQRHFKNLKTFVKHQQLHN--------ETYQNNVKQV-----RRLLEAKQEKSMY 127 +C+ C + F T HQ++H E Q +++ RR+ ++ Sbjct: 187 HECTDCGKAFTQKSTLKMHQKIHTGERSYICIECGQAFIQKTHLIAHRRIHTGEKPYECS 246 Query: 128 GVYNTFTTEERWALHP----------CSKSDPMYS----------MKRRKNIHACTICGK 167 +F ++ + +H C++ ++S ++ R+ CT CGK Sbjct: 247 NCGKSFISKSQLQVHQRVHTRVKPYICTEYGKVFSNNSNLVTHKKVQSREKSSICTECGK 306 Query: 168 MFPSQSKLDRHVLIHTGQRPFKCVLCTKSFRQST-------------------------- 201 F +S+L H IHTG++P++C C K+F Q + Sbjct: 307 AFTYRSELIIHQRIHTGEKPYECSDCGKAFTQKSALTVHQRIHTGEKSYICMKCGLAFIQ 366 Query: 202 --HLKIHQLTHSEERPFQCCFCQKGFKIQSKLLKHKQIHTRNKAFRALLLKKRRTESRPL 259 HL HQ+ H+ E+P +C C K F +S+L HK+IHT K + K T L Sbjct: 367 KAHLIAHQIIHTGEKPHKCGHCGKLFTSKSQLHVHKRIHTGEKPYMCNKCGKAFTNRSNL 426 Query: 260 --PNKLNANQGGFENGEIGES-EENNPLDVHSIYIV---PFQCPKCEKCFESEQILNEHS 313 K + + + + G++ + + L H P++C C K F + LN H Sbjct: 427 ITHQKTHTGEKSYICSKCGKAFTQRSDLITHQRIHTGEKPYECNTCGKAFTQKSHLNIHQ 486 Query: 314 CFAARSGKIP-SRFKRSYNYKTIVKKILAKLKRARSKKLDNFQSEKKVFKKSFLRNCDLI 372 + +++N K+I+ + K+ + + K +F+ + + Sbjct: 487 KIHTGERQYECHECGKAFNQKSIL-IVHQKIHTGEKPYVCTECGRAFIRKSNFITHQRIH 545 Query: 373 SGEQSSEQTQRTFVGSLGKHGTYKT--IGNRKKKTLTLPFSWQNMGKNLKGILTTENILS 430 +GE+ E GK T K+ + ++ T P+ GK G N+ Sbjct: 546 TGEKPYE------CSDCGKSFTSKSQLLVHQPVHTGEKPYVCAECGKAFSG---RSNLSK 596 Query: 431 IDNSVNKKDLSICGSSGEEFFNNCEVLQCGFSVPRENIRTRHKICPCDKCEKVFPSISKL 490 + + IC G+ F E+ + I T K C C K F S+L Sbjct: 597 HQKTHTGEKPYICSECGKTFRQKSEL------ITHHRIHTGEKPYECSDCGKSFTKKSQL 650 Query: 491 KRHYLIHTGQRPFGCNICGKSFRQSAHLKRHEQTHNEKSPY-ASLCQVEFGNFNNLSNHS 549 + H IHTG++P+ C CGK+F ++L +H+ TH PY +C F + S H Sbjct: 651 QVHQRIHTGEKPYVCAECGKAFTDRSNLNKHQTTHTGDKPYKCGICGKGFVQKSVFSVHQ 710 Query: 550 GNN 552 ++ Sbjct: 711 SSH 713 Score = 139 bits (351), Expect = 7e-33 Identities = 135/572 (23%), Positives = 231/572 (40%), Gaps = 73/572 (12%) Query: 165 CGKMFPSQSKLDRHVLIHTGQRPFKCVLCTKSFRQSTHLKIHQLTHSEERPFQCCFCQKG 224 C K+ + + ++ G++ ++C K F Q + LK+H + E+ + C C K Sbjct: 52 CRKILSYKQVSSQPQKMYPGEKAYECAKFEKIFTQKSQLKVHLKVLAGEKLYVCIECGKA 111 Query: 225 FKIQSKLLKHKQIHTRNKAFRALLLKKR--RTESRPLPNKLNANQGGFENGEIGES-EEN 281 F + + + H++ H R K F+ K + S +++ + +E + G+ N Sbjct: 112 FVQKPEFIIHQKTHMREKPFKCNECGKSFFQVSSLFRHQRIHTGEKLYECSQCGKGFSYN 171 Query: 282 NPLDVHSIYIV---PFQCPKCEKCFESEQILNEH----------------SCFAARSGKI 322 + L +H +C C K F + L H F ++ I Sbjct: 172 SDLSIHEKIHTGERHHECTDCGKAFTQKSTLKMHQKIHTGERSYICIECGQAFIQKTHLI 231 Query: 323 PSR----FKRSYNYKTIVKKILAKL-----KRARSKKLDNFQSEKKVFKKSFLRNCDLIS 373 R ++ Y K ++K +R ++ +E + K F N +L++ Sbjct: 232 AHRRIHTGEKPYECSNCGKSFISKSQLQVHQRVHTRVKPYICTE---YGKVFSNNSNLVT 288 Query: 374 GEQSSEQTQRTFVGSLGKHGTYKT--IGNRKKKTLTLPFSWQNMGKNLKGILTTENILSI 431 ++ + + + GK TY++ I +++ T P+ + GK T ++ L++ Sbjct: 289 HKKVQSREKSSICTECGKAFTYRSELIIHQRIHTGEKPYECSDCGK----AFTQKSALTV 344 Query: 432 DNSVNKKDLS-ICGSSGEEFFNNCEVLQCGFSVPRENIRTRHKICPCDKCEKVFPSISKL 490 ++ + S IC G F +Q + + I T K C C K+F S S+L Sbjct: 345 HQRIHTGEKSYICMKCGLAF------IQKAHLIAHQIIHTGEKPHKCGHCGKLFTSKSQL 398 Query: 491 KRHYLIHTGQRPFGCNICGKSFRQSAHLKRHEQTH-NEKSPYASLCQVEFGNFNNLSNHS 549 H IHTG++P+ CN CGK+F ++L H++TH EKS S C F ++L H Sbjct: 399 HVHKRIHTGEKPYMCNKCGKAFTNRSNLITHQKTHTGEKSYICSKCGKAFTQRSDLITHQ 458 Query: 550 ------------------GNNVNYNASQQCQAPGVQKYEVSESDQMSGVKA---ESQDFI 588 + N Q+ G ++YE E + K+ Q Sbjct: 459 RIHTGEKPYECNTCGKAFTQKSHLNIHQKIHT-GERQYECHECGKAFNQKSILIVHQKIH 517 Query: 589 PGSTGQPCLPNVLLESEQSNPFCSYSEHQEKNDVFLYRCSVCAKSFRSPSKLERHYLIHA 648 G C +SN H + Y CS C KSF S S+L H +H Sbjct: 518 TGEKPYVCTECGRAFIRKSNFITHQRIHTGEKP---YECSDCGKSFTSKSQLLVHQPVHT 574 Query: 649 GQKPFECSVCGKTFRQAPHWKRHQLTHFKERP 680 G+KP+ C+ CGK F + +HQ TH E+P Sbjct: 575 GEKPYVCAECGKAFSGRSNLSKHQKTHTGEKP 606 Score = 110 bits (275), Expect = 4e-24 Identities = 61/199 (30%), Positives = 91/199 (45%), Gaps = 17/199 (8%) Query: 25 RPYVCNICFKHFETPSKLARHYLIHTGQKPFECDVCHKTFRQLVHLERHQLTHS--LPFK 82 +PYVC C + F S H IHTG+KP+EC C K+F L HQ H+ P+ Sbjct: 521 KPYVCTECGRAFIRKSNFITHQRIHTGEKPYECSDCGKSFTSKSQLLVHQPVHTGEKPYV 580 Query: 83 CSICQRHFKNLKTFVKHQQLHNETYQNNVKQVRRLLEAKQEKSMYGVYNTFTTEERWALH 142 C+ C + F KHQ+ H + + K E + + T E+ + Sbjct: 581 CAECGKAFSGRSNLSKHQKTHTGEKPYICSECGKTFRQKSELITH--HRIHTGEKPYECS 638 Query: 143 PCSKSDPMYSMKRRKNIH----------ACTICGKMFPSQSKLDRHVLIHTGQRPFKCVL 192 C KS ++ K + +H C CGK F +S L++H HTG +P+KC + Sbjct: 639 DCGKS---FTKKSQLQVHQRIHTGEKPYVCAECGKAFTDRSNLNKHQTTHTGDKPYKCGI 695 Query: 193 CTKSFRQSTHLKIHQLTHS 211 C K F Q + +HQ +H+ Sbjct: 696 CGKGFVQKSVFSVHQSSHA 714 Score = 51.2 bits (121), Expect = 3e-06 Identities = 29/92 (31%), Positives = 41/92 (44%), Gaps = 5/92 (5%) Query: 594 QPCLPNVLLESEQSNPFCSYSEHQEKNDVFL-----YRCSVCAKSFRSPSKLERHYLIHA 648 Q C L + Q SY + + Y C+ K F S+L+ H + A Sbjct: 39 QSCPGEKLWDHNQCRKILSYKQVSSQPQKMYPGEKAYECAKFEKIFTQKSQLKVHLKVLA 98 Query: 649 GQKPFECSVCGKTFRQAPHWKRHQLTHFKERP 680 G+K + C CGK F Q P + HQ TH +E+P Sbjct: 99 GEKLYVCIECGKAFVQKPEFIIHQKTHMREKP 130 >gi|22749331 zinc finger protein 585A [Homo sapiens] Length = 714 Score = 209 bits (532), Expect = 7e-54 Identities = 178/670 (26%), Positives = 285/670 (42%), Gaps = 88/670 (13%) Query: 22 PRNRPYVCNICFKHFETPSKLARHYLIHTGQKPFECDVCHKTFRQLVHLERHQLTH--SL 79 P + Y C K F S+L H + G+K + C C K F Q HQ TH Sbjct: 70 PGEKAYECAKFEKIFTQKSQLKVHLKVLAGEKLYVCIECGKAFVQKPEFIIHQKTHMREK 129 Query: 80 PFKCSICQRHFKNLKTFVKHQQLHNETYQNNVKQVRRLLEAKQEKSMYGVYNTFTTEERW 139 PFKC+ C + F + + +HQ++H +L E Q + + + E+ Sbjct: 130 PFKCNECGKSFFQVSSLFRHQRIHTG---------EKLYECSQCGKGFSYNSDLSIHEK- 179 Query: 140 ALHPCSKSDPMYSMKRRKNIHACTICGKMFPSQSKLDRHVLIHTGQRPFKCVLCTKSFRQ 199 +++ +R H CT CGK F +S L H IHTG+R + C+ C ++F Q Sbjct: 180 ----------IHTGERH---HECTDCGKAFTQKSTLKMHQKIHTGERSYICIECGQAFIQ 226 Query: 200 STHLKIHQLTHSEERPFQCCFCQKGFKIQSKLLKHKQIHTRNKAFRALLLKKRRTESRPL 259 THL H+ H+ E+P++C C K F +S+L H+++HTR K + TE Sbjct: 227 KTHLIAHRRIHTGEKPYECSNCGKSFISKSQLQVHQRVHTRVKPYIC-------TEY--- 276 Query: 260 PNKLNANQGGFENGEIGESEENNPLDVHSIYIVPFQCPKCEKCF--ESEQILNEHSCFAA 317 K+ +N + +S E + + C +C K F SE I+++ Sbjct: 277 -GKVFSNNSNLVTHKKVQSREKSSI-----------CTECGKAFTYRSELIIHQR----I 320 Query: 318 RSGKIPSRFKRSYNYKTIVKKILAKLKRARSKKLDNFQSEKKVFK--KSFLRNCDLISGE 375 +G+ P Y K K +++ + K +F++ LI+ + Sbjct: 321 HTGEKP------YECSDCGKAFTQKSALTVHQRIHTGEKSYICMKCGLAFIQKAHLIAHQ 374 Query: 376 QSSEQTQRTFVGSLGKHGTYKTIGNRKKKTLT--LPFSWQNMGKNLKGILTTENILSIDN 433 + G GK T K+ + K+ T P+ GK N+++ Sbjct: 375 IIHTGEKPHKCGHCGKLFTSKSQLHVHKRIHTGEKPYMCNKCGK---AFTNRSNLITHQK 431 Query: 434 SVNKKDLSICGSSGEEFFNNCEVLQCGFSVPRENIRTRHKICPCDKCEKVFPSISKLKRH 493 + + IC G+ F ++ + + I T K C+ C K F S L H Sbjct: 432 THTGEKSYICSKCGKAFTQRSDL------ITHQRIHTGEKPYECNTCGKAFTQKSHLNIH 485 Query: 494 YLIHTGQRPFGCNICGKSFRQSAHLKRHEQTHNEKSPYASL-CQVEFGNFNNLSNHSGNN 552 IHTG+R + C+ CGK+F Q + L H++ H + PY C F +N H + Sbjct: 486 QKIHTGERQYECHECGKAFNQKSILIVHQKIHTGEKPYVCTECGRAFIRKSNFITHQRIH 545 Query: 553 VNYNASQQCQAPGVQKYEVSESDQMSGVKAESQDFIPGSTGQPCLPNVLLESEQS-NPFC 611 G + YE S+ + K++ P TG+ P V E ++ + Sbjct: 546 T-----------GEKPYECSDCGKSFTSKSQLLVHQPVHTGEK--PYVCAECGKAFSGRS 592 Query: 612 SYSEHQEKNDVFL-YRCSVCAKSFRSPSKLERHYLIHAGQKPFECSVCGKTFRQAPHWKR 670 + S+HQ+ + Y CS C K+FR S+L H+ IH G+KP+ECS CGK+F + + Sbjct: 593 NLSKHQKTHTGEKPYICSECGKTFRQKSELITHHRIHTGEKPYECSDCGKSFTKKSQLQV 652 Query: 671 HQLTHFKERP 680 HQ H E+P Sbjct: 653 HQRIHTGEKP 662 Score = 164 bits (415), Expect = 3e-40 Identities = 147/603 (24%), Positives = 244/603 (40%), Gaps = 89/603 (14%) Query: 23 RNRPYVCNICFKHFETPSKLARHYLIHTGQKPFECDVCHKTFRQLVHLERHQLTHS--LP 80 R +P+ CN C K F S L RH IHTG+K +EC C K F L H+ H+ Sbjct: 127 REKPFKCNECGKSFFQVSSLFRHQRIHTGEKLYECSQCGKGFSYNSDLSIHEKIHTGERH 186 Query: 81 FKCSICQRHFKNLKTFVKHQQLHN--------ETYQNNVKQV-----RRLLEAKQEKSMY 127 +C+ C + F T HQ++H E Q +++ RR+ ++ Sbjct: 187 HECTDCGKAFTQKSTLKMHQKIHTGERSYICIECGQAFIQKTHLIAHRRIHTGEKPYECS 246 Query: 128 GVYNTFTTEERWALHP----------CSKSDPMYS----------MKRRKNIHACTICGK 167 +F ++ + +H C++ ++S ++ R+ CT CGK Sbjct: 247 NCGKSFISKSQLQVHQRVHTRVKPYICTEYGKVFSNNSNLVTHKKVQSREKSSICTECGK 306 Query: 168 MFPSQSKLDRHVLIHTGQRPFKCVLCTKSFRQST-------------------------- 201 F +S+L H IHTG++P++C C K+F Q + Sbjct: 307 AFTYRSELIIHQRIHTGEKPYECSDCGKAFTQKSALTVHQRIHTGEKSYICMKCGLAFIQ 366 Query: 202 --HLKIHQLTHSEERPFQCCFCQKGFKIQSKLLKHKQIHTRNKAFRALLLKKRRTESRPL 259 HL HQ+ H+ E+P +C C K F +S+L HK+IHT K + K T L Sbjct: 367 KAHLIAHQIIHTGEKPHKCGHCGKLFTSKSQLHVHKRIHTGEKPYMCNKCGKAFTNRSNL 426 Query: 260 --PNKLNANQGGFENGEIGES-EENNPLDVHSIYIV---PFQCPKCEKCFESEQILNEHS 313 K + + + + G++ + + L H P++C C K F + LN H Sbjct: 427 ITHQKTHTGEKSYICSKCGKAFTQRSDLITHQRIHTGEKPYECNTCGKAFTQKSHLNIHQ 486 Query: 314 CFAARSGKIP-SRFKRSYNYKTIVKKILAKLKRARSKKLDNFQSEKKVFKKSFLRNCDLI 372 + +++N K+I+ + K+ + + K +F+ + + Sbjct: 487 KIHTGERQYECHECGKAFNQKSIL-IVHQKIHTGEKPYVCTECGRAFIRKSNFITHQRIH 545 Query: 373 SGEQSSEQTQRTFVGSLGKHGTYKT--IGNRKKKTLTLPFSWQNMGKNLKGILTTENILS 430 +GE+ E GK T K+ + ++ T P+ GK G N+ Sbjct: 546 TGEKPYE------CSDCGKSFTSKSQLLVHQPVHTGEKPYVCAECGKAFSG---RSNLSK 596 Query: 431 IDNSVNKKDLSICGSSGEEFFNNCEVLQCGFSVPRENIRTRHKICPCDKCEKVFPSISKL 490 + + IC G+ F E+ + I T K C C K F S+L Sbjct: 597 HQKTHTGEKPYICSECGKTFRQKSEL------ITHHRIHTGEKPYECSDCGKSFTKKSQL 650 Query: 491 KRHYLIHTGQRPFGCNICGKSFRQSAHLKRHEQTHNEKSPY-ASLCQVEFGNFNNLSNHS 549 + H IHTG++P+ C CGK+F ++L +H+ TH PY +C F + S H Sbjct: 651 QVHQRIHTGEKPYVCAECGKAFTDRSNLNKHQTTHTGDKPYKCGICGKGFVQKSVFSVHQ 710 Query: 550 GNN 552 ++ Sbjct: 711 SSH 713 Score = 139 bits (351), Expect = 7e-33 Identities = 135/572 (23%), Positives = 231/572 (40%), Gaps = 73/572 (12%) Query: 165 CGKMFPSQSKLDRHVLIHTGQRPFKCVLCTKSFRQSTHLKIHQLTHSEERPFQCCFCQKG 224 C K+ + + ++ G++ ++C K F Q + LK+H + E+ + C C K Sbjct: 52 CRKILSYKQVSSQPQKMYPGEKAYECAKFEKIFTQKSQLKVHLKVLAGEKLYVCIECGKA 111 Query: 225 FKIQSKLLKHKQIHTRNKAFRALLLKKR--RTESRPLPNKLNANQGGFENGEIGES-EEN 281 F + + + H++ H R K F+ K + S +++ + +E + G+ N Sbjct: 112 FVQKPEFIIHQKTHMREKPFKCNECGKSFFQVSSLFRHQRIHTGEKLYECSQCGKGFSYN 171 Query: 282 NPLDVHSIYIV---PFQCPKCEKCFESEQILNEH----------------SCFAARSGKI 322 + L +H +C C K F + L H F ++ I Sbjct: 172 SDLSIHEKIHTGERHHECTDCGKAFTQKSTLKMHQKIHTGERSYICIECGQAFIQKTHLI 231 Query: 323 PSR----FKRSYNYKTIVKKILAKL-----KRARSKKLDNFQSEKKVFKKSFLRNCDLIS 373 R ++ Y K ++K +R ++ +E + K F N +L++ Sbjct: 232 AHRRIHTGEKPYECSNCGKSFISKSQLQVHQRVHTRVKPYICTE---YGKVFSNNSNLVT 288 Query: 374 GEQSSEQTQRTFVGSLGKHGTYKT--IGNRKKKTLTLPFSWQNMGKNLKGILTTENILSI 431 ++ + + + GK TY++ I +++ T P+ + GK T ++ L++ Sbjct: 289 HKKVQSREKSSICTECGKAFTYRSELIIHQRIHTGEKPYECSDCGK----AFTQKSALTV 344 Query: 432 DNSVNKKDLS-ICGSSGEEFFNNCEVLQCGFSVPRENIRTRHKICPCDKCEKVFPSISKL 490 ++ + S IC G F +Q + + I T K C C K+F S S+L Sbjct: 345 HQRIHTGEKSYICMKCGLAF------IQKAHLIAHQIIHTGEKPHKCGHCGKLFTSKSQL 398 Query: 491 KRHYLIHTGQRPFGCNICGKSFRQSAHLKRHEQTH-NEKSPYASLCQVEFGNFNNLSNHS 549 H IHTG++P+ CN CGK+F ++L H++TH EKS S C F ++L H Sbjct: 399 HVHKRIHTGEKPYMCNKCGKAFTNRSNLITHQKTHTGEKSYICSKCGKAFTQRSDLITHQ 458 Query: 550 ------------------GNNVNYNASQQCQAPGVQKYEVSESDQMSGVKA---ESQDFI 588 + N Q+ G ++YE E + K+ Q Sbjct: 459 RIHTGEKPYECNTCGKAFTQKSHLNIHQKIHT-GERQYECHECGKAFNQKSILIVHQKIH 517 Query: 589 PGSTGQPCLPNVLLESEQSNPFCSYSEHQEKNDVFLYRCSVCAKSFRSPSKLERHYLIHA 648 G C +SN H + Y CS C KSF S S+L H +H Sbjct: 518 TGEKPYVCTECGRAFIRKSNFITHQRIHTGEKP---YECSDCGKSFTSKSQLLVHQPVHT 574 Query: 649 GQKPFECSVCGKTFRQAPHWKRHQLTHFKERP 680 G+KP+ C+ CGK F + +HQ TH E+P Sbjct: 575 GEKPYVCAECGKAFSGRSNLSKHQKTHTGEKP 606 Score = 110 bits (275), Expect = 4e-24 Identities = 61/199 (30%), Positives = 91/199 (45%), Gaps = 17/199 (8%) Query: 25 RPYVCNICFKHFETPSKLARHYLIHTGQKPFECDVCHKTFRQLVHLERHQLTHS--LPFK 82 +PYVC C + F S H IHTG+KP+EC C K+F L HQ H+ P+ Sbjct: 521 KPYVCTECGRAFIRKSNFITHQRIHTGEKPYECSDCGKSFTSKSQLLVHQPVHTGEKPYV 580 Query: 83 CSICQRHFKNLKTFVKHQQLHNETYQNNVKQVRRLLEAKQEKSMYGVYNTFTTEERWALH 142 C+ C + F KHQ+ H + + K E + + T E+ + Sbjct: 581 CAECGKAFSGRSNLSKHQKTHTGEKPYICSECGKTFRQKSELITH--HRIHTGEKPYECS 638 Query: 143 PCSKSDPMYSMKRRKNIH----------ACTICGKMFPSQSKLDRHVLIHTGQRPFKCVL 192 C KS ++ K + +H C CGK F +S L++H HTG +P+KC + Sbjct: 639 DCGKS---FTKKSQLQVHQRIHTGEKPYVCAECGKAFTDRSNLNKHQTTHTGDKPYKCGI 695 Query: 193 CTKSFRQSTHLKIHQLTHS 211 C K F Q + +HQ +H+ Sbjct: 696 CGKGFVQKSVFSVHQSSHA 714 Score = 51.2 bits (121), Expect = 3e-06 Identities = 29/92 (31%), Positives = 41/92 (44%), Gaps = 5/92 (5%) Query: 594 QPCLPNVLLESEQSNPFCSYSEHQEKNDVFL-----YRCSVCAKSFRSPSKLERHYLIHA 648 Q C L + Q SY + + Y C+ K F S+L+ H + A Sbjct: 39 QSCPGEKLWDHNQCRKILSYKQVSSQPQKMYPGEKAYECAKFEKIFTQKSQLKVHLKVLA 98 Query: 649 GQKPFECSVCGKTFRQAPHWKRHQLTHFKERP 680 G+K + C CGK F Q P + HQ TH +E+P Sbjct: 99 GEKLYVCIECGKAFVQKPEFIIHQKTHMREKP 130 >gi|49574543 zinc finger protein 616 [Homo sapiens] Length = 781 Score = 209 bits (531), Expect = 9e-54 Identities = 175/693 (25%), Positives = 296/693 (42%), Gaps = 125/693 (18%) Query: 15 CVVANKLPRNRPYVCNICFKHFETPSKLARHYLIHTGQKPFECDVCHKTFRQLVHLERHQ 74 C+V+ + R + YVCN C K F+ S L H IHT +KP++C+ C K F + L H+ Sbjct: 174 CLVSPHI-REKTYVCNECGKAFKASSSLINHQRIHTTEKPYKCNECGKAFHRASLLTVHK 232 Query: 75 LTHS--LPFKCSICQRHFKNLKTFVKHQQLHNETYQNNVKQVRRLLEAKQEKSMYGVYNT 132 + H+ ++C +C + F+ FV+HQ+ H Sbjct: 233 VVHTRGKSYQCDVCGKIFRKNSYFVRHQRSH----------------------------- 263 Query: 133 FTTEERWALHPCSKSDPMYS-MKRRKNIHA------CTICGKMFPSQSKLDRHVLIHTGQ 185 T ++ + + C KS S + + IH C +CGK F + L H +HTG+ Sbjct: 264 -TGQKPYICNECGKSFSKSSHLAVHQRIHTGEKPYKCNLCGKSFSQRVHLRLHQTVHTGE 322 Query: 186 RPFKCVLCTKSFRQSTHLKIHQLTHSEERPFQCCFCQKGFKIQSKLLKHKQIHTRNKAF- 244 RPFKC C K+F++S++L +HQ+ H+ ++P++C C K F+ +S L+ H++IH+ K + Sbjct: 323 RPFKCNECGKTFKRSSNLTVHQVIHAGKKPYKCDVCGKAFRHRSNLVCHRRIHSGEKQYK 382 Query: 245 ----------RALLLKKRRTESRPLPNKLNANQGGFENGEIGESEENNPLDVHSIYIVPF 294 R+ L RR + P K N E G++ + + L VH Sbjct: 383 CNECGKVFSKRSSLAVHRRIHTVEKPCKCN------ECGKV--FSKRSSLAVHQRIHTGQ 434 Query: 295 QCPKCEKCFESEQILNEHSCFAARSGKIPSRFKRSYNYKTIVKKILAKLKRARSKKLDNF 354 + KC KC ++ ++HS A +I + +++Y K + A +++ Sbjct: 435 KTYKCNKC---GKVYSKHSHLAVH-WRIHTG-EKAYKCNECGKVFSIHSRLAAHQRIHTG 489 Query: 355 QSEKKVFK--KSFLRNCDLISGEQSSEQTQRTFVGSLGKHGTYKTIGNRKKKTLT--LPF 410 + K + K F ++ L + + GK + ++ R ++ T P+ Sbjct: 490 EKPYKCNECGKVFSQHSRLAVHRRIHTGEKPYKCKECGKVFSDRSAFARHRRIHTGEKPY 549 Query: 411 SWQNMGKNLKGILTTENILSIDNSVNKKDLSICGSSGEEFF--NNCEVLQCGFS--VPRE 466 + GK + + + L++ ++ SGE+ + N C + +S V Sbjct: 550 KCKECGK----VFSQCSRLTVHRRIH---------SGEKPYKCNECGKVYSQYSHLVGHR 596 Query: 467 NIRTRHKICPCDKCEKVFPSISKLKRHYLIHTGQRPFGCNICGKSFRQSAHLKRHEQTHN 526 + T K C +C K F S L RH IHTG++P+ CN CG SF Q HL+ H+ H Sbjct: 597 RVHTGEKPYKCHECGKAFNQGSTLNRHQRIHTGEKPYKCNQCGNSFSQRVHLRLHQTVHT 656 Query: 527 EKSPY-ASLCQVEFGNFNNLSNHSGNNVNYNASQQCQAPGVQKYEVSESDQMSGVKAESQ 585 PY + C F +NL+ H Q G + Y+ E ++ + Sbjct: 657 GDRPYKCNECGKTFKRSSNLTAH-----------QIIHAGKKPYKCDECGKVFRHSSHLV 705 Query: 586 DFIPGSTGQPCLPNVLLESEQSNPFCSYSEHQEKNDVFLYRCSVCAKSFRSPSKLERHYL 645 TG+ Y+C C K+F L +H Sbjct: 706 SHQRIHTGEK----------------------------RYKCIECGKAFGRLFSLSKHQR 737 Query: 646 IHAGQKPFECSVCGKTFRQAPHWKRHQLTHFKE 678 IH+G+KP++C+ CGK+F +H++ H E Sbjct: 738 IHSGKKPYKCNECGKSFICRSGLTKHRIRHTGE 770 Score = 184 bits (466), Expect = 3e-46 Identities = 147/532 (27%), Positives = 234/532 (43%), Gaps = 54/532 (10%) Query: 25 RPYVCNICFKHFETPSKLARHYLIHTGQKPFECDVCHKTFRQLVHLERHQLTHS--LPFK 82 +PY+CN C K F S LA H IHTG+KP++C++C K+F Q VHL HQ H+ PFK Sbjct: 267 KPYICNECGKSFSKSSHLAVHQRIHTGEKPYKCNLCGKSFSQRVHLRLHQTVHTGERPFK 326 Query: 83 CSICQRHFKNLKTFVKHQQLH--NETYQNNV--KQVRRLLEAKQEKSMYGVYNTFTTEER 138 C+ C + FK HQ +H + Y+ +V K R + ++ + E++ Sbjct: 327 CNECGKTFKRSSNLTVHQVIHAGKKPYKCDVCGKAFRHRSNLVCHRRIH------SGEKQ 380 Query: 139 WALHPCSKS-DPMYSMKRRKNIHA------CTICGKMFPSQSKLDRHVLIHTGQRPFKCV 191 + + C K S+ + IH C CGK+F +S L H IHTGQ+ +KC Sbjct: 381 YKCNECGKVFSKRSSLAVHRRIHTVEKPCKCNECGKVFSKRSSLAVHQRIHTGQKTYKCN 440 Query: 192 LCTKSFRQSTHLKIHQLTHSEERPFQCCFCQKGFKIQSKLLKHKQIHTRNKAFRALLLKK 251 C K + + +HL +H H+ E+ ++C C K F I S+L H++IHT K ++ K Sbjct: 441 KCGKVYSKHSHLAVHWRIHTGEKAYKCNECGKVFSIHSRLAAHQRIHTGEKPYKCNECGK 500 Query: 252 RRTESRPLP--NKLNANQGGFENGEIGESEENNPLDVHSIYI----VPFQCPKCEKCFES 305 ++ L +++ + ++ E G+ + I P++C +C K F Sbjct: 501 VFSQHSRLAVHRRIHTGEKPYKCKECGKVFSDRSAFARHRRIHTGEKPYKCKECGKVFSQ 560 Query: 306 EQILNEHSCFAARSGKIPSRFKRSYNYKTIVKKILAKLKRARSKKLDNFQSEKKVFKK-- 363 L H SG+ P + + ++ + +K K F + Sbjct: 561 CSRLTVHR--RIHSGEKPYKCNECGKVYSQYSHLVGHRRVHTGEKPYKCHECGKAFNQGS 618 Query: 364 SFLRNCDLISGEQ--SSEQTQRTFVGS--LGKHGTYKTIGNRKKKTLTLPFSWQNMGKNL 419 + R+ + +GE+ Q +F L H T T G+R P+ GK Sbjct: 619 TLNRHQRIHTGEKPYKCNQCGNSFSQRVHLRLHQTVHT-GDR-------PYKCNECGKTF 670 Query: 420 K--GILTTENILSIDNSVNKKDLSICGSSGEEFFNNCEVLQCGFSVPRENIRTRHKICPC 477 K LT I+ K C G+ F ++ + V + I T K C Sbjct: 671 KRSSNLTAHQIIHAGKKPYK-----CDECGKVFRHSSHL------VSHQRIHTGEKRYKC 719 Query: 478 DKCEKVFPSISKLKRHYLIHTGQRPFGCNICGKSFRQSAHLKRHEQTHNEKS 529 +C K F + L +H IH+G++P+ CN CGKSF + L +H H +S Sbjct: 720 IECGKAFGRLFSLSKHQRIHSGKKPYKCNECGKSFICRSGLTKHRIRHTGES 771 Score = 174 bits (442), Expect = 2e-43 Identities = 159/664 (23%), Positives = 254/664 (38%), Gaps = 118/664 (17%) Query: 40 SKLARHYLIHTGQKPFECDVCHKTFRQLVHLERHQLTHSLPFKCSICQRHFKNLKTFVKH 99 S+LA + T + +EC+ KT + H + C+ C + FK + + H Sbjct: 146 SRLAELQKVQTEGRLYECNETEKTGNNGCLVSPH--IREKTYVCNECGKAFKASSSLINH 203 Query: 100 QQLHNETYQNNVKQVRRLLEAKQEKSMYGVYNTFTTEERWALHPCSKSDPMYSM------ 153 Q++H TTE+ + + C K+ S+ Sbjct: 204 QRIH------------------------------TTEKPYKCNECGKAFHRASLLTVHKV 233 Query: 154 -KRRKNIHACTICGKMFPSQSKLDRHVLIHTGQRPFKCVLCTKSFRQSTHLKIHQLTHSE 212 R + C +CGK+F S RH HTGQ+P+ C C KSF +S+HL +HQ H+ Sbjct: 234 VHTRGKSYQCDVCGKIFRKNSYFVRHQRSHTGQKPYICNECGKSFSKSSHLAVHQRIHTG 293 Query: 213 ERPFQCCFCQKGFKIQSKLLKHKQIHTRNKAFRALLLKKRRTESRPLPNKLNANQGGFEN 272 E+P++C C K F + L H+ +HT + F+ Sbjct: 294 EKPYKCNLCGKSFSQRVHLRLHQTVHTGERPFKC-------------------------- 327 Query: 273 GEIGES-EENNPLDVHSIYIV---PFQCPKCEKCFESEQILNEHSCFAARSGKIPSRFKR 328 E G++ + ++ L VH + P++C C K F L H SG+ + Sbjct: 328 NECGKTFKRSSNLTVHQVIHAGKKPYKCDVCGKAFRHRSNLVCHR--RIHSGE------K 379 Query: 329 SYNYKTIVKKILAKLKRARSKKLDNFQSEKKVFKKSFLRNCDLISGEQSSEQT-QRTFVG 387 Y K + A +++ + K C + ++SS QR G Sbjct: 380 QYKCNECGKVFSKRSSLAVHRRIHTVEKPCKC------NECGKVFSKRSSLAVHQRIHTG 433 Query: 388 SLGKHGTYKT--IGNRKKKTLTLPFSWQ-NMGKNLKGILTTENILSIDNSV--------N 436 TYK G K L W+ + G+ + SI + + Sbjct: 434 QK----TYKCNKCGKVYSKHSHLAVHWRIHTGEKAYKCNECGKVFSIHSRLAAHQRIHTG 489 Query: 437 KKDLSICGSSGEEFFNNCEVLQCGFSVPRENIRTRHKICPCDKCEKVFPSISKLKRHYLI 496 +K C G+ F + + I T K C +C KVF S RH I Sbjct: 490 EKPYK-CNECGKVFSQHSRL------AVHRRIHTGEKPYKCKECGKVFSDRSAFARHRRI 542 Query: 497 HTGQRPFGCNICGKSFRQSAHLKRHEQTHNEKSPY-ASLCQVEFGNFNNLSNHSGNNVNY 555 HTG++P+ C CGK F Q + L H + H+ + PY + C + +++L H + Sbjct: 543 HTGEKPYKCKECGKVFSQCSRLTVHRRIHSGEKPYKCNECGKVYSQYSHLVGHRRVHTG- 601 Query: 556 NASQQCQAPGVQKYEVSESDQMSGVKAESQDFIPGSTGQPCLPNVLLESEQSNPFCSYSE 615 +C G + S ++ + + + G V L Q+ Sbjct: 602 EKPYKCHECGKAFNQGSTLNRHQRIHTGEKPYKCNQCGNSFSQRVHLRLHQT-------V 654 Query: 616 HQEKNDVFLYRCSVCAKSFRSPSKLERHYLIHAGQKPFECSVCGKTFRQAPHWKRHQLTH 675 H Y+C+ C K+F+ S L H +IHAG+KP++C CGK FR + H HQ H Sbjct: 655 HTGDRP---YKCNECGKTFKRSSNLTAHQIIHAGKKPYKCDECGKVFRHSSHLVSHQRIH 711 Query: 676 FKER 679 E+ Sbjct: 712 TGEK 715 Score = 154 bits (388), Expect = 3e-37 Identities = 142/594 (23%), Positives = 236/594 (39%), Gaps = 102/594 (17%) Query: 97 VKHQQLHNETYQNNVKQVRRLLEAKQEKSMYGVYNTFTTEERWALHPCSKSDPMYSMKRR 156 V++ + N+ N ++ L + + E +Y T T L S R Sbjct: 131 VENNHIENQLTSNFESRLAELQKVQTEGRLYECNETEKTGNNGCL---------VSPHIR 181 Query: 157 KNIHACTICGKMFPSQSKLDRHVLIHTGQRPFKCVLCTKSFRQSTHLKIHQLTHSEERPF 216 + + C CGK F + S L H IHT ++P+KC C K+F +++ L +H++ H+ + + Sbjct: 182 EKTYVCNECGKAFKASSSLINHQRIHTTEKPYKCNECGKAFHRASLLTVHKVVHTRGKSY 241 Query: 217 QCCFCQKGFKIQSKLLKHKQIHTRNKAFRALLLKKRRTESRPLP--NKLNANQGGFENGE 274 QC C K F+ S ++H++ HT K + K ++S L +++ + ++ Sbjct: 242 QCDVCGKIFRKNSYFVRHQRSHTGQKPYICNECGKSFSKSSHLAVHQRIHTGEKPYKCNL 301 Query: 275 IGES-EENNPLDVHSIYIV---PFQCPKCEKCFESEQILNEHSCFAARSGKIPSRFKRSY 330 G+S + L +H PF+C +C K F+ L H A GK P Sbjct: 302 CGKSFSQRVHLRLHQTVHTGERPFKCNECGKTFKRSSNLTVHQVIHA--GKKP------- 352 Query: 331 NYKTIVKKILAKLKRARSKKLDN--FQSEKKVFKKSFLRNCDLISGEQSSEQTQRTFVGS 388 YK + K R RS + + S +K +K C + ++SS Sbjct: 353 -YKC---DVCGKAFRHRSNLVCHRRIHSGEKQYK---CNECGKVFSKRSS---------- 395 Query: 389 LGKHGTYKTIGNRKKKTLTLPFSWQNMGKNLKGILTTENILSIDNSVNKKDLSI-CGSSG 447 L H R+ T+ P GK + + + L++ ++ + C G Sbjct: 396 LAVH--------RRIHTVEKPCKCNECGK----VFSKRSSLAVHQRIHTGQKTYKCNKCG 443 Query: 448 EEFFNNCEVLQCGFSVPRENIRTRHKICPCDKCEKVFPSISKLKRHYLIHTGQRPFGCNI 507 + + + + I T K C++C KVF S+L H IHTG++P+ CN Sbjct: 444 KVYSKHSHL------AVHWRIHTGEKAYKCNECGKVFSIHSRLAAHQRIHTGEKPYKCNE 497 Query: 508 CGKSFRQSAHLKRHEQTHNEKSPY-ASLCQVEFGNFNNLSNHSGNNVNYNASQQCQAPGV 566 CGK F Q + L H + H + PY C F + + + H + G Sbjct: 498 CGKVFSQHSRLAVHRRIHTGEKPYKCKECGKVFSDRSAFARHRRIHT-----------GE 546 Query: 567 QKYEVSESDQMSGVKAESQDFIPGSTGQPCLPNVLLESEQSNPFCSYSEHQEKNDVFLYR 626 + Y+ E ++ S+ S H + Y+ Sbjct: 547 KPYKCKECGKVF-------------------------SQCSRLTVHRRIHSGEKP---YK 578 Query: 627 CSVCAKSFRSPSKLERHYLIHAGQKPFECSVCGKTFRQAPHWKRHQLTHFKERP 680 C+ C K + S L H +H G+KP++C CGK F Q RHQ H E+P Sbjct: 579 CNECGKVYSQYSHLVGHRRVHTGEKPYKCHECGKAFNQGSTLNRHQRIHTGEKP 632 >gi|154800445 zinc finger protein 62 homolog [Homo sapiens] Length = 840 Score = 207 bits (527), Expect = 3e-53 Identities = 177/700 (25%), Positives = 276/700 (39%), Gaps = 131/700 (18%) Query: 25 RPYVCNICFKHFETPSKLARHYLIHTGQKPFECDVCHKTFRQLVHLERHQLTHS--LPFK 82 +PY C C K F S L H IHTG+KP+ECD+C KTF L H+ H+ P++ Sbjct: 191 KPYECGECGKAFRNSSGLRVHKRIHTGEKPYECDICGKTFSNSSGLRVHKRIHTGEKPYE 250 Query: 83 CSICQRHFKNLKTFVKHQQLHNETYQNNVKQVRRLLEAKQEKSMYGVYNT---------- 132 C C + F +T + H+ +H + + + V +T Sbjct: 251 CDECGKAFITCRTLLNHKSIHFGDKPYKCDECEKSFNYSSLLIQHKVIHTGEKPYECDEC 310 Query: 133 ----------------FTTEERWALHPCSKSDPM-------YSMKRRKNIHACTICGKMF 169 T E+ + C K+ S+ K H C CGK F Sbjct: 311 GKAFRNSSGLIVHKRIHTGEKPYKCDVCGKAFSYSSGLAVHKSIHPGKKAHECKECGKSF 370 Query: 170 PSQSKLDRHVLIHTGQRPFKCVLCTKSFRQSTHLKIHQLTHSEERPFQCCFCQKGFKIQS 229 S L +H IHTG+RP+ C +C K+FR + LK+H+ H+ E+P++C C K + +S Sbjct: 371 SYNSLLLQHRTIHTGERPYVCDVCGKTFRNNAGLKVHRRLHTGEKPYKCDVCGKAYISRS 430 Query: 230 KLLKHKQIHTRNKAFRALLLKKRRTESRPLP--NKLNANQGGFENGEIGESEENNP-LDV 286 L HK IH K ++ +K S L +++ + F E G++ NN L V Sbjct: 431 SLKNHKGIHLGEKPYKCSYCEKSFNYSSALEQHKRIHTREKPFGCDECGKAFRNNSGLKV 490 Query: 287 HSIYIV---PFQCPKCEKCFESEQILNEHSCFAARSGKIPSRF----KRSYNYKTIVKKI 339 H P++C +C K + S L H + G+ P + K Y+T+ Sbjct: 491 HKRIHTGERPYKCEECGKAYISLSSLINHK--SVHPGEKPFKCDECEKAFITYRTLT--- 545 Query: 340 LAKLKRARSKKLDNFQSEKKVFKKSFLRNCDLISGEQSSEQTQRTFVGSLGKHGTYKTIG 399 + KKV CD+ + + L +H Sbjct: 546 ----------------NHKKVHLGEKPYKCDVC-------EKSFNYTSLLSQH------- 575 Query: 400 NRKKKTLTLPFSWQNMGKNLKGILTTENILSIDNSVNKKDLSICGSSGEEFFNNCEVLQC 459 R+ T P+ K + + + I + +CG + + ++ ++ Sbjct: 576 -RRVHTREKPYECDRCEKVFRNNSSLKVHKRIHTGERPYECDVCGKA---YISHSSLINH 631 Query: 460 GFSVPRENIRTRHKICPCDKCEKVFPSISKLKRHYLIHTGQRPFGCNICGKSFRQSAHLK 519 + P + T CD+C K F S L H +H G++PF C CGKSF S+ L Sbjct: 632 KSTHPGKTPHT------CDECGKAFFSSRTLISHKRVHLGEKPFKCVECGKSFSYSSLLS 685 Query: 520 RHEQTHNEKSPY-ASLCQVEFGNFNNLSNHSGNNVNYNASQQCQAPGVQKYEVSESDQMS 578 +H++ H + PY C F N + L+ H + G + YE E Sbjct: 686 QHKRIHTGEKPYVCDRCGKAFRNSSGLTVHKRIHT-----------GEKPYECDE----- 729 Query: 579 GVKAESQDFIPGSTGQPCLPNVLLESEQSNPFCSYSEHQEKNDVFLYRCSVCAKSFRSPS 638 G+ + + L + +S HQ K Y C C KSF S Sbjct: 730 -------------CGKAYISHSSLINHKS-------VHQGKQP---YNCE-CGKSFNYRS 765 Query: 639 KLERHYLIHAGQKPFECSVCGKTFRQAPHWKRHQLTHFKE 678 L++H IH G+KP+ C+ CGK F + +H+ TH E Sbjct: 766 VLDQHKRIHTGKKPYRCNECGKAFNIRSNLTKHKRTHTGE 805 Score = 206 bits (525), Expect = 4e-53 Identities = 181/682 (26%), Positives = 276/682 (40%), Gaps = 126/682 (18%) Query: 29 CNICFKHFETPSKLARHYLIHTGQKPFECDVCHKTFRQLVHLERHQLTHS--LPFKCSIC 86 C+ C K F S L +H IHTG+KP+EC C K FR L H+ H+ P++C IC Sbjct: 167 CDECGKSFNYSSVLDQHKRIHTGEKPYECGECGKAFRNSSGLRVHKRIHTGEKPYECDIC 226 Query: 87 QRHFKNLKTFVKHQQLHNETYQNNVKQVRRLLEAKQEKSMYGVYNTFTTEERWALHPCSK 146 + F N H+++H T E+ + C K Sbjct: 227 GKTFSNSSGLRVHKRIH------------------------------TGEKPYECDECGK 256 Query: 147 SD-PMYSMKRRKNIH------ACTICGKMFPSQSKLDRHVLIHTGQRPFKCVLCTKSFRQ 199 + ++ K+IH C C K F S L +H +IHTG++P++C C K+FR Sbjct: 257 AFITCRTLLNHKSIHFGDKPYKCDECEKSFNYSSLLIQHKVIHTGEKPYECDECGKAFRN 316 Query: 200 STHLKIHQLTHSEERPFQCCFCQKGFKIQSKLLKHKQIHTRNKA-----------FRALL 248 S+ L +H+ H+ E+P++C C K F S L HK IH KA + +LL Sbjct: 317 SSGLIVHKRIHTGEKPYKCDVCGKAFSYSSGLAVHKSIHPGKKAHECKECGKSFSYNSLL 376 Query: 249 LKKRRTESRPLPNKLNANQGGFENGEIGESEENNPLDVHSIYIV---PFQCPKCEKCFES 305 L+ R + P + F N N L VH P++C C K + S Sbjct: 377 LQHRTIHTGERPYVCDVCGKTFRN--------NAGLKVHRRLHTGEKPYKCDVCGKAYIS 428 Query: 306 EQILNEHSCFAARSGKIP---SRFKRSYNYKTIVKKILAKLKRARSKKLDNFQSEKKVFK 362 L H G+ P S ++S+NY + +++ K R K + K Sbjct: 429 RSSLKNHK--GIHLGEKPYKCSYCEKSFNYSSALEQ--HKRIHTREKPFGCDECGKAFRN 484 Query: 363 KSFLRNCDLI-SGEQ--SSEQTQRTFVGSLGKHGTYKTIGNRKKKTLTLPFSWQNMGKNL 419 S L+ I +GE+ E+ + ++ SL +K++ +K PF K Sbjct: 485 NSGLKVHKRIHTGERPYKCEECGKAYI-SLSSLINHKSVHPGEK-----PFKCDECEKAF 538 Query: 420 KGILTTENILSIDNSVNKKDLSICGSSGEEFFNNCEVLQCGFSVPRENIRTRHKICPCDK 479 T N + +C E+ FN +L + TR K CD+ Sbjct: 539 ITYRTLTNHKKVHLGEKPYKCDVC----EKSFNYTSLLS-----QHRRVHTREKPYECDR 589 Query: 480 CEKVFPSISKLKRHYLIHTGQRPFGCNICGKSFRQSAHLKRHEQTHNEKSPYA-SLCQVE 538 CEKVF + S LK H IHTG+RP+ C++CGK++ + L H+ TH K+P+ C Sbjct: 590 CEKVFRNNSSLKVHKRIHTGERPYECDVCGKAYISHSSLINHKSTHPGKTPHTCDECGKA 649 Query: 539 FGNFNNLSNHSGNNVNYNASQQCQAPGVQKYEVSESDQMSGVKAESQDFIPGSTGQPCLP 598 F + L +H ++ + C E +S S + ++ + G Sbjct: 650 FFSSRTLISHKRVHLGEKPFK-C-------VECGKSFSYSSLLSQHKRIHTGEKP----- 696 Query: 599 NVLLESEQSNPFCSYSEHQEKNDVFLYRCSVCAKSFRSPSKLERHYLIHAGQKPFECSVC 658 Y C C K+FR+ S L H IH G+KP+EC C Sbjct: 697 --------------------------YVCDRCGKAFRNSSGLTVHKRIHTGEKPYECDEC 730 Query: 659 GKTFRQAPHWKRHQLTHFKERP 680 GK + H+ H ++P Sbjct: 731 GKAYISHSSLINHKSVHQGKQP 752 Score = 205 bits (521), Expect = 1e-52 Identities = 185/701 (26%), Positives = 289/701 (41%), Gaps = 108/701 (15%) Query: 29 CNICFKHFETPSKLARHYLIHTGQKPFECDVCHKTFRQLVHLERHQLTHS--LPFKCSIC 86 C+ C K F+ S+L +H ++HTG+K +ECD C TFR L H+ H+ P+KC C Sbjct: 83 CDECGKSFKYNSRLVQHKIMHTGEKRYECDDCGGTFRSSSSLRVHKRIHTGEKPYKCEEC 142 Query: 87 QRHFKNLKTFVKHQQLHNE-------------TYQNNVKQVRRLL------------EAK 121 + + + + + H+ H+ Y + + Q +R+ +A Sbjct: 143 GKAYMSYSSLINHKSTHSGEKNCKCDECGKSFNYSSVLDQHKRIHTGEKPYECGECGKAF 202 Query: 122 QEKSMYGVYNTFTTEER-WALHPCSKSDPMYS-MKRRKNIHA------CTICGKMFPSQS 173 + S V+ T E+ + C K+ S ++ K IH C CGK F + Sbjct: 203 RNSSGLRVHKRIHTGEKPYECDICGKTFSNSSGLRVHKRIHTGEKPYECDECGKAFITCR 262 Query: 174 KLDRHVLIHTGQRPFKCVLCTKSFRQSTHLKIHQLTHSEERPFQCCFCQKGFKIQSKLLK 233 L H IH G +P+KC C KSF S+ L H++ H+ E+P++C C K F+ S L+ Sbjct: 263 TLLNHKSIHFGDKPYKCDECEKSFNYSSLLIQHKVIHTGEKPYECDECGKAFRNSSGLIV 322 Query: 234 HKQIHTRNKAFRALLLKKRRTESRPLP--NKLNANQGGFENGEIGESEENNPLDVHSIYI 291 HK+IHT K ++ + K + S L ++ + E E G+S N L + I Sbjct: 323 HKRIHTGEKPYKCDVCGKAFSYSSGLAVHKSIHPGKKAHECKECGKSFSYNSLLLQHRTI 382 Query: 292 ----VPFQCPKCEKCFESEQILNEHSCFAARSGKIPSRFKRSYNYKTIVKKILAKLKRAR 347 P+ C C K F + L H +G+ P YK V A + R+ Sbjct: 383 HTGERPYVCDVCGKTFRNNAGLKVHR--RLHTGEKP--------YKCDVCG-KAYISRSS 431 Query: 348 SKKLDNFQSEKKVFKKSFLRNCDLISGEQSSEQTQRTFVGSLGKHGTYKTIGNRKKKTLT 407 K +K +K S+ S SS Q +K I R+K Sbjct: 432 LKNHKGIHLGEKPYKCSYCEK----SFNYSSALEQ------------HKRIHTREK---- 471 Query: 408 LPFSWQNMGK---NLKGILTTENILSIDNSVNKKDLSICGSSGEEFFNNCEVLQCGFSVP 464 PF GK N G+ + I + + C G+ + + ++ Sbjct: 472 -PFGCDECGKAFRNNSGLKVHKRIHTGERPYK------CEECGKAYISLSSLIN------ 518 Query: 465 RENIRTRHKICPCDKCEKVFPSISKLKRHYLIHTGQRPFGCNICGKSFRQSAHLKRHEQT 524 +++ K CD+CEK F + L H +H G++P+ C++C KSF ++ L +H + Sbjct: 519 HKSVHPGEKPFKCDECEKAFITYRTLTNHKKVHLGEKPYKCDVCEKSFNYTSLLSQHRRV 578 Query: 525 HNEKSPY-ASLCQVEFGNFNNLSNHSGNNVNYNASQQCQAPGVQKYEVSESDQMSGVKAE 583 H + PY C+ F N ++L H + +C G K +S S ++ Sbjct: 579 HTREKPYECDRCEKVFRNNSSLKVHKRIHTG-ERPYECDVCG--KAYISHSSLINHKSTH 635 Query: 584 SQDFIPGSTGQPCLPNVLLESEQSNPFCSYSEHQEKNDVFL----YRCSVCAKSFRSPSK 639 PG T C E F S V L ++C C KSF S Sbjct: 636 -----PGKTPHTC-------DECGKAFFSSRTLISHKRVHLGEKPFKCVECGKSFSYSSL 683 Query: 640 LERHYLIHAGQKPFECSVCGKTFRQAPHWKRHQLTHFKERP 680 L +H IH G+KP+ C CGK FR + H+ H E+P Sbjct: 684 LSQHKRIHTGEKPYVCDRCGKAFRNSSGLTVHKRIHTGEKP 724 Score = 195 bits (496), Expect = 1e-49 Identities = 149/562 (26%), Positives = 253/562 (45%), Gaps = 74/562 (13%) Query: 24 NRPYVCNICFKHFETPSKLARHYLIHTGQKPFECDVCHKTFRQLVHLERHQLTHS--LPF 81 ++PY C+ C K F S L +H +IHTG+KP+ECD C K FR L H+ H+ P+ Sbjct: 274 DKPYKCDECEKSFNYSSLLIQHKVIHTGEKPYECDECGKAFRNSSGLIVHKRIHTGEKPY 333 Query: 82 KCSICQRHFKNLKTFVKHQQLHNETYQNNVKQVRRLLEAKQEKSMYGVYNTFTTEERWAL 141 KC +C + F H+ +H + K+ + YN+ + R Sbjct: 334 KCDVCGKAFSYSSGLAVHKSIHPGKKAHECKECGKSFS----------YNSLLLQHR--- 380 Query: 142 HPCSKSDPMYSMKRRKNIHACTICGKMFPSQSKLDRHVLIHTGQRPFKCVLCTKSFRQST 201 ++ + + C +CGK F + + L H +HTG++P+KC +C K++ + Sbjct: 381 ----------TIHTGERPYVCDVCGKTFRNNAGLKVHRRLHTGEKPYKCDVCGKAYISRS 430 Query: 202 HLKIHQLTHSEERPFQCCFCQKGFKIQSKLLKHKQIHTRNKAFRALLLKK--RRTESRPL 259 LK H+ H E+P++C +C+K F S L +HK+IHTR K F K R + Sbjct: 431 SLKNHKGIHLGEKPYKCSYCEKSFNYSSALEQHKRIHTREKPFGCDECGKAFRNNSGLKV 490 Query: 260 PNKLNANQGGFENGEIGE-----SEENNPLDVHSIYIVPFQCPKCEKCFESEQILNEHSC 314 +++ + ++ E G+ S N VH PF+C +CEK F + + L H Sbjct: 491 HKRIHTGERPYKCEECGKAYISLSSLINHKSVHP-GEKPFKCDECEKAFITYRTLTNHK- 548 Query: 315 FAARSGKIPSR---FKRSYNYKTIV---KKILAKLKR---ARSKKLDNFQSEKKVFK--- 362 G+ P + ++S+NY +++ +++ + K R +K+ S KV K Sbjct: 549 -KVHLGEKPYKCDVCEKSFNYTSLLSQHRRVHTREKPYECDRCEKVFRNNSSLKVHKRIH 607 Query: 363 ------------KSFLRNCDLISGEQSSEQTQRTFVGSLGK--HGTYKTIGNRKKKTLTL 408 K+++ + LI+ + + GK + I +++ Sbjct: 608 TGERPYECDVCGKAYISHSSLINHKSTHPGKTPHTCDECGKAFFSSRTLISHKRVHLGEK 667 Query: 409 PFSWQNMGKNLKGILTTENILSIDNSVNKKDLS-ICGSSGEEFFNNCEVLQCGFSVPREN 467 PF GK+ + ++LS ++ + +C G+ F N+ G +V + Sbjct: 668 PFKCVECGKS----FSYSSLLSQHKRIHTGEKPYVCDRCGKAFRNS-----SGLTV-HKR 717 Query: 468 IRTRHKICPCDKCEKVFPSISKLKRHYLIHTGQRPFGCNICGKSFRQSAHLKRHEQTHNE 527 I T K CD+C K + S S L H +H G++P+ C CGKSF + L +H++ H Sbjct: 718 IHTGEKPYECDECGKAYISHSSLINHKSVHQGKQPYNCE-CGKSFNYRSVLDQHKRIHTG 776 Query: 528 KSPY-ASLCQVEFGNFNNLSNH 548 K PY + C F +NL+ H Sbjct: 777 KKPYRCNECGKAFNIRSNLTKH 798 Score = 186 bits (472), Expect = 6e-47 Identities = 167/647 (25%), Positives = 253/647 (39%), Gaps = 130/647 (20%) Query: 52 QKPFECDVCHKTFRQLVHLERHQLTHS--LPFKCSICQRHFKNLKTFVKHQQLHNETYQN 109 +K +CD C K+F+ L +H++ H+ ++C C F++ + H+++H Sbjct: 78 KKLHKCDECGKSFKYNSRLVQHKIMHTGEKRYECDDCGGTFRSSSSLRVHKRIH------ 131 Query: 110 NVKQVRRLLEAKQEKSMYGVYNTFTTEERWALHPCSKSDPMYS-MKRRKNIHA------C 162 T E+ + C K+ YS + K+ H+ C Sbjct: 132 ------------------------TGEKPYKCEECGKAYMSYSSLINHKSTHSGEKNCKC 167 Query: 163 TICGKMFPSQSKLDRHVLIHTGQRPFKCVLCTKSFRQSTHLKIHQLTHSEERPFQCCFCQ 222 CGK F S LD+H IHTG++P++C C K+FR S+ L++H+ H+ E+P++C C Sbjct: 168 DECGKSFNYSSVLDQHKRIHTGEKPYECGECGKAFRNSSGLRVHKRIHTGEKPYECDICG 227 Query: 223 KGFKIQSKLLKHKQIHTRNKAFRALLLKKRRTESRPLPNKLNANQGGFENGEIGESEENN 282 K F S L HK+IHT K + K R L N + + G Sbjct: 228 KTFSNSSGLRVHKRIHTGEKPYECDECGKAFITCRTLLNHKSIHFGD------------- 274 Query: 283 PLDVHSIYIVPFQCPKCEKCFESEQILNEHSCFAARSGKIPSRFKRSYNYKTIVKKILAK 342 P++C +CEK F +L +H K+ ++ Y K Sbjct: 275 ---------KPYKCDECEKSFNYSSLLIQH--------KVIHTGEKPYECDECGKAFRNS 317 Query: 343 LKRARSKKLDNFQSEKKVFKKSFLRNCDLISGEQSSEQTQRTFVGSLGKHGTYKTIGNRK 402 K++ + K CD+ + F S G +K+I K Sbjct: 318 SGLIVHKRIHTGEKPYK---------CDVCG---------KAFSYSSGL-AVHKSIHPGK 358 Query: 403 K----KTLTLPFSWQNMGKNLKGILTTENILSIDNSVNKKDLSICGSSGEEFFNNCEVLQ 458 K K FS+ ++ + I T E +C G+ F NN Sbjct: 359 KAHECKECGKSFSYNSLLLQHRTIHTGERPY------------VCDVCGKTFRNN----- 401 Query: 459 CGFSVPRENIRTRHKICPCDKCEKVFPSISKLKRHYLIHTGQRPFGCNICGKSFRQSAHL 518 G V R + T K CD C K + S S LK H IH G++P+ C+ C KSF S+ L Sbjct: 402 AGLKVHR-RLHTGEKPYKCDVCGKAYISRSSLKNHKGIHLGEKPYKCSYCEKSFNYSSAL 460 Query: 519 KRHEQTHNEKSPY-ASLCQVEFGNFNNLSNHSGNNVNYNASQQCQAPGVQKYEVSESDQM 577 ++H++ H + P+ C F N + L H + +C+ G +S Sbjct: 461 EQHKRIHTREKPFGCDECGKAFRNNSGLKVHKRIHTG-ERPYKCEECGKAYISLSSLINH 519 Query: 578 SGVKAESQDFIPGSTGQPCLPNVLLESEQSNPFCSYSEHQEKNDVFL----YRCSVCAKS 633 V PG C E F +Y V L Y+C VC KS Sbjct: 520 KSVH-------PGEKPFKC-------DECEKAFITYRTLTNHKKVHLGEKPYKCDVCEKS 565 Query: 634 FRSPSKLERHYLIHAGQKPFECSVCGKTFRQAPHWKRHQLTHFKERP 680 F S L +H +H +KP+EC C K FR K H+ H ERP Sbjct: 566 FNYTSLLSQHRRVHTREKPYECDRCEKVFRNNSSLKVHKRIHTGERP 612 Score = 162 bits (410), Expect = 1e-39 Identities = 139/553 (25%), Positives = 228/553 (41%), Gaps = 116/553 (20%) Query: 22 PRNRPYVCNICFKHFETPSKLARHYLIHTGQKPFECDVCHKTFRQLVHLERHQLTHS--L 79 P + + C C K F S L +H IHTG++P+ CDVC KTFR L+ H+ H+ Sbjct: 356 PGKKAHECKECGKSFSYNSLLLQHRTIHTGERPYVCDVCGKTFRNNAGLKVHRRLHTGEK 415 Query: 80 PFKCSICQRHFKNLKTFVKHQQLHNETYQNNVKQVRRLLEAKQEKSMYGVYNTFTTEERW 139 P+KC +C + + + + H+ +H L K K Y Sbjct: 416 PYKCDVCGKAYISRSSLKNHKGIH--------------LGEKPYKCSY------------ 449 Query: 140 ALHPCSKS-DPMYSMKRRKNIH------ACTICGKMFPSQSKLDRHVLIHTGQRPFKCVL 192 C KS + ++++ K IH C CGK F + S L H IHTG+RP+KC Sbjct: 450 ----CEKSFNYSSALEQHKRIHTREKPFGCDECGKAFRNNSGLKVHKRIHTGERPYKCEE 505 Query: 193 CTKSFRQSTHLKIHQLTHSEERPFQCCFCQKGFKIQSKLLKHKQIHTRNKAFR------- 245 C K++ + L H+ H E+PF+C C+K F L HK++H K ++ Sbjct: 506 CGKAYISLSSLINHKSVHPGEKPFKCDECEKAFITYRTLTNHKKVHLGEKPYKCDVCEKS 565 Query: 246 ----ALLLKKRRTESRPLPNKLNANQGGFENGEIGESEENNPLDVHSIYIV---PFQCPK 298 +LL + RR +R P + + + F N N+ L VH P++C Sbjct: 566 FNYTSLLSQHRRVHTREKPYECDRCEKVFRN--------NSSLKVHKRIHTGERPYECDV 617 Query: 299 CEKCFESEQILNEHSCFAARSGKIPSRFKRSYNYKTIVKKILAKLKRARSKKLDNFQSEK 358 C K + S L H + GK P Sbjct: 618 CGKAYISHSSLINHK--STHPGKTPHTCDEC----------------------------- 646 Query: 359 KVFKKSFLRNCDLISGEQSSEQTQRTFVGSLGKHGTYKTIGNRKKKTLT--LPFSWQNMG 416 K+F + LIS ++ + GK +Y ++ ++ K+ T P+ G Sbjct: 647 ---GKAFFSSRTLISHKRVHLGEKPFKCVECGKSFSYSSLLSQHKRIHTGEKPYVCDRCG 703 Query: 417 K---NLKGILTTENILSIDNSVNKKDLSICGSSGEEFFNNCEVLQCGFSVPRENIRTRHK 473 K N G+ + I + + C G+ + ++ ++ +++ + Sbjct: 704 KAFRNSSGLTVHKRIHTGEKPYE------CDECGKAYISHSSLIN------HKSVHQGKQ 751 Query: 474 ICPCDKCEKVFPSISKLKRHYLIHTGQRPFGCNICGKSFRQSAHLKRHEQTHNEKSPYAS 533 C+ C K F S L +H IHTG++P+ CN CGK+F ++L +H++TH + S Sbjct: 752 PYNCE-CGKSFNYRSVLDQHKRIHTGKKPYRCNECGKAFNIRSNLTKHKRTHTGEE---S 807 Query: 534 LCQVEFGNFNNLS 546 L + G+++ S Sbjct: 808 LNVIYVGSYSGTS 820 Score = 119 bits (299), Expect = 7e-27 Identities = 118/516 (22%), Positives = 212/516 (41%), Gaps = 95/516 (18%) Query: 178 HVLIHTGQRPFKCVLCTKSFRQSTHLKIHQLTHSEERPFQCCFCQKGFKIQSKLLKHKQI 237 H + GQR + ++ +++ + Q T++ ++ +C C K FK S+L++HK + Sbjct: 43 HQTMPIGQRGSEQGKRVENINGTSYPSLQQKTNAVKKLHKCDECGKSFKYNSRLVQHKIM 102 Query: 238 HTRNKAFRALLLKKRRTESRPLPNKLNANQGGFENGEIGESEENNPLDVHSIYIV---PF 294 HT K + + G G ++ L VH P+ Sbjct: 103 HTGEKRYEC-------------------DDCG------GTFRSSSSLRVHKRIHTGEKPY 137 Query: 295 QCPKCEKCFES-EQILNEHSCFAARSGKIPSRFKRSYNYKTIVKKILAKLKRARSKKLDN 353 +C +C K + S ++N S + +S+NY +++ + Sbjct: 138 KCEECGKAYMSYSSLINHKSTHSGEKNCKCDECGKSFNYSSVLDQ--------------- 182 Query: 354 FQSEKKVFKKSFLRNCDLISGEQSSE--QTQRTFVGSLGKHGTYKTIGNRKKKTLTLPFS 411 K++ +GE+ E + + F S G +K I +K P+ Sbjct: 183 ---HKRIH-----------TGEKPYECGECGKAFRNSSGLR-VHKRIHTGEK-----PYE 222 Query: 412 WQNMGK---NLKGILTTENILSIDNSVNKKDLSICGSSGEEFFNNCEVLQCGFSVPRENI 468 GK N G+ + I + + C G+ F + C + ++I Sbjct: 223 CDICGKTFSNSSGLRVHKRIHTGEKPYE------CDECGKAF------ITCRTLLNHKSI 270 Query: 469 RTRHKICPCDKCEKVFPSISKLKRHYLIHTGQRPFGCNICGKSFRQSAHLKRHEQTHNEK 528 K CD+CEK F S L +H +IHTG++P+ C+ CGK+FR S+ L H++ H + Sbjct: 271 HFGDKPYKCDECEKSFNYSSLLIQHKVIHTGEKPYECDECGKAFRNSSGLIVHKRIHTGE 330 Query: 529 SPY-ASLCQVEFGNFNNLSNHSGNNVNYNASQQCQAPGVQKYEVSESDQMSGVKAESQDF 587 PY +C F + L+ H + PG + +E E + + Sbjct: 331 KPYKCDVCGKAFSYSSGLAVHKSIH-----------PGKKAHECKECGKSFSYNSLLLQH 379 Query: 588 IPGSTGQ-PCLPNVLLESEQSNPFCSYSEHQEKNDVFLYRCSVCAKSFRSPSKLERHYLI 646 TG+ P + +V ++ ++N + Y+C VC K++ S S L+ H I Sbjct: 380 RTIHTGERPYVCDVCGKTFRNNAGLKVHRRLHTGEK-PYKCDVCGKAYISRSSLKNHKGI 438 Query: 647 HAGQKPFECSVCGKTFRQAPHWKRHQLTHFKERPQG 682 H G+KP++CS C K+F + ++H+ H +E+P G Sbjct: 439 HLGEKPYKCSYCEKSFNYSSALEQHKRIHTREKPFG 474 Score = 60.5 bits (145), Expect = 5e-09 Identities = 38/133 (28%), Positives = 57/133 (42%), Gaps = 29/133 (21%) Query: 25 RPYVCNICFKHFETPSKLARHYLIHTGQKPFECDVCHKTF--------RQLVH------- 69 +PYVC+ C K F S L H IHTG+KP+ECD C K + + VH Sbjct: 695 KPYVCDRCGKAFRNSSGLTVHKRIHTGEKPYECDECGKAYISHSSLINHKSVHQGKQPYN 754 Query: 70 ------------LERHQLTHS--LPFKCSICQRHFKNLKTFVKHQQLHNETYQNNVKQVR 115 L++H+ H+ P++C+ C + F KH++ H NV V Sbjct: 755 CECGKSFNYRSVLDQHKRIHTGKKPYRCNECGKAFNIRSNLTKHKRTHTGEESLNVIYVG 814 Query: 116 RLLEAKQEKSMYG 128 Q+++ G Sbjct: 815 SYSGTSQKRTYEG 827 >gi|115511042 zinc finger protein 493 isoform 1 [Homo sapiens] Length = 646 Score = 207 bits (526), Expect = 3e-53 Identities = 147/523 (28%), Positives = 241/523 (46%), Gaps = 44/523 (8%) Query: 25 RPYVCNICFKHFETPSKLARHYLIHTGQKPFECDVCHKTFRQLVHLERHQLTHS--LPFK 82 +PY C C F S L RH LIHT +KP++C+ KTF Q L H++ H+ P+K Sbjct: 135 KPYKCEECGTSFYQFSYLTRHKLIHTREKPYKCEQYGKTFNQSSTLTGHKIIHNGEKPYK 194 Query: 83 CSICQRHFKNLKTFVKHQQLHNETYQNNVKQVRRLLEAKQEKSMYGVYNTFTTEER-WAL 141 C C + F T KH+ +H E + ++ +A +E S + T E+ + Sbjct: 195 CEECGKAFSIFSTPTKHKIIHTEEKSHRCEEY---CKAYKESSHLTTHKRIHTGEKPYKC 251 Query: 142 HPCSKSDPMYSMKRRKNI-------HACTICGKMFPSQSKLDRHVLIHTGQRPFKCVLCT 194 C K+ ++S + I H C CGK + S L H IHTG++P+KC C Sbjct: 252 EECGKAFSIFSTLTKHKIIHTEEKSHRCEECGKAYKESSHLTTHKRIHTGEKPYKCEECG 311 Query: 195 KSFRQSTHLKIHQLTHSEERPFQCCFCQKGFKIQSKLLKHKQIHTRNKAFRALLLKKRRT 254 K+F + L H++ H+EE+P++C C K FK S L KH+ IHT K ++ K Sbjct: 312 KTFSVFSILTKHKIIHTEEKPYKCEECGKAFKRSSTLTKHRIIHTEEKPYKCEECGKAFN 371 Query: 255 ESRPLP--NKLNANQGGFENGEIGES-EENNPLDVHSIYIV---PFQCPKCEKCFESEQI 308 +S L ++ + ++ E G++ + ++ L +H + P++C +C K F Sbjct: 372 QSSTLSIHKIIHTGEKPYKCEECGKAFKRSSTLTIHKMIHTGEKPYKCEECGKAFNRSSH 431 Query: 309 LNEHSCFAARSGKIPSRFKRSYNYKTIVKKILAKLKRARSKKLDNFQSEKKVFKKSFLRN 368 L H +G P + K ++ + KK + K F +S + + Sbjct: 432 LTTHK--RIHTGHKPYKCKECGKSFSVFSTLTKHKIIHTDKKPYKCEECGKAFNRSSILS 489 Query: 369 CD--LISGEQSSEQTQRTFVGSLGKHGTYKTIGNRKKKTLTLPFSWQNMGK--NLKGILT 424 + +GE+ + + G K ++ G+++ ++ P+ + GK ++ LT Sbjct: 490 IHKKIHTGEKPYKCEE---CGKAFKRSSHLA-GHKQIHSVQKPYKCEECGKAFSIFSTLT 545 Query: 425 TENILSIDNSVNKKDLSICGSSGEEF--FNNCEVLQCGFSVPRENIRTRHKICPCDKCEK 482 I+ + K C G+ F F+N + I T K C C++C K Sbjct: 546 KHKIIHTEEKPYK-----CEKCGKTFYRFSNLNT--------HKIIHTGEKPCKCEECGK 592 Query: 483 VFPSISKLKRHYLIHTGQRPFGCNICGKSFRQSAHLKRHEQTH 525 F S L +H LIHTG +P+ C CGK+FR+S+HL RH+ H Sbjct: 593 AFNHSSNLIKHKLIHTGDKPYKCEACGKAFRRSSHLSRHKIIH 635 Score = 203 bits (517), Expect = 4e-52 Identities = 182/700 (26%), Positives = 286/700 (40%), Gaps = 133/700 (19%) Query: 23 RNRPYVCNICFKHFETPSKLARHYLIHTGQKPFECDVCHKTFRQLVHLERHQLTH--SLP 80 +++ + C+ K F RH HTG+KPF+C C K+F L+HL +H+ H Sbjct: 22 QSKIFQCDKYVKVFHKLLNSNRHNTKHTGKKPFKCKKCGKSFCMLLHLCQHKRIHIRENS 81 Query: 81 FKCSICQRHFKNLKTFVKHQQLHNETYQNNVKQVRRLLEAKQEKSMYGVYNTFTTEERWA 140 ++C C + F T +H+++H T E+ Sbjct: 82 YRCEECGKAFIWFSTLTRHRRVH-------------------------------TGEKSY 110 Query: 141 LHPCSKSDPMYS-MKRRKNIHA------CTICGKMFPSQSKLDRHVLIHTGQRPFKCVLC 193 + C KS S + K IH C CG F S L RH LIHT ++P+KC Sbjct: 111 KYECGKSFNQDSNLTTHKRIHTGQKPYKCEECGTSFYQFSYLTRHKLIHTREKPYKCEQY 170 Query: 194 TKSFRQSTHLKIHQLTHSEERPFQCCFCQKGFKIQSKLLKHKQIHTRNKAFRALLLKKRR 253 K+F QS+ L H++ H+ E+P++C C K F I S KHK IHT K+ R K Sbjct: 171 GKTFNQSSTLTGHKIIHNGEKPYKCEECGKAFSIFSTPTKHKIIHTEEKSHRCEEYCKAY 230 Query: 254 TESRPLP--NKLNANQGGFENGEIGES-EENNPLDVHSIYIV---PFQCPKCEKCFESEQ 307 ES L +++ + ++ E G++ + L H I +C +C K ++ Sbjct: 231 KESSHLTTHKRIHTGEKPYKCEECGKAFSIFSTLTKHKIIHTEEKSHRCEECGKAYKESS 290 Query: 308 ILNEHSCFAARSGKIPSRFK---RSYNYKTIVKKILAKLKRARSKKLDNFQSEKKVFKKS 364 L H +G+ P + + ++++ +I+ K K+ K + K + S Sbjct: 291 HLTTHK--RIHTGEKPYKCEECGKTFSVFSILTK--HKIIHTEEKPYKCEECGKAFKRSS 346 Query: 365 FLRNCDLISGEQ---SSEQTQRTFVGSLGKHGTYKTIGNRKKKTLTLPFSWQNMGKNLK- 420 L +I E+ E+ + F S +K I +K P+ + GK K Sbjct: 347 TLTKHRIIHTEEKPYKCEECGKAFNQS-STLSIHKIIHTGEK-----PYKCEECGKAFKR 400 Query: 421 -GILTTENILSIDNSVNKKDLSICGSSGEEFFNNCEVL---------------QCGFSVP 464 LT ++ K C G+ F + + +CG S Sbjct: 401 SSTLTIHKMIHTGEKPYK-----CEECGKAFNRSSHLTTHKRIHTGHKPYKCKECGKSFS 455 Query: 465 RENIRTRHKIC-------PCDKCEKVFPSISKLKRHYLIHTGQRPFGCNICGKSFRQSAH 517 + T+HKI C++C K F S L H IHTG++P+ C CGK+F++S+H Sbjct: 456 VFSTLTKHKIIHTDKKPYKCEECGKAFNRSSILSIHKKIHTGEKPYKCEECGKAFKRSSH 515 Query: 518 LKRHEQTHNEKSPY-ASLCQVEFGNFNNLSNHSGNNVNYNASQQCQAPGVQKYEVSESDQ 576 L H+Q H+ + PY C F F+ L+ H + +C+ G Y S + Sbjct: 516 LAGHKQIHSVQKPYKCEECGKAFSIFSTLTKHKIIHTE-EKPYKCEKCGKTFYRFSNLNT 574 Query: 577 MSGVKAESQDFIPGSTGQ-PCLPNVLLESEQSNPFCSYSEHQEKNDVFLYRCSVCAKSFR 635 + TG+ PC +C C K+F Sbjct: 575 HKII----------HTGEKPC-----------------------------KCEECGKAFN 595 Query: 636 SPSKLERHYLIHAGQKPFECSVCGKTFRQAPHWKRHQLTH 675 S L +H LIH G KP++C CGK FR++ H RH++ H Sbjct: 596 HSSNLIKHKLIHTGDKPYKCEACGKAFRRSSHLSRHKIIH 635 Score = 172 bits (435), Expect = 1e-42 Identities = 169/669 (25%), Positives = 264/669 (39%), Gaps = 160/669 (23%) Query: 30 NICFKHFETPSKLARHYLIHTGQKPFECDVCHKTFRQLVHLERHQLTHS--LPFKCSICQ 87 N C H E ++L YL T K F+CD K F +L++ RH H+ PFKC C Sbjct: 2 NECNVHKEGYNEL-NQYLTTTQSKIFQCDKYVKVFHKLLNSNRHNTKHTGKKPFKCKKCG 60 Query: 88 RHFKNLKTFVKHQQLHNETYQNNVKQVRRLLEAKQEKSMYGVYNTFTTEERWALHPCSKS 147 + F L LH C Sbjct: 61 KSFCML-----------------------------------------------LHLCQHK 73 Query: 148 DPMYSMKRRKNIHACTICGKMFPSQSKLDRHVLIHTGQRPFKCVLCTKSFRQSTHLKIHQ 207 + R+N + C CGK F S L RH +HTG++ +K C KSF Q ++L H+ Sbjct: 74 ----RIHIRENSYRCEECGKAFIWFSTLTRHRRVHTGEKSYKYE-CGKSFNQDSNLTTHK 128 Query: 208 LTHSEERPFQCCFCQKGFKIQSKLLKHKQIHTRNKAFRALLLKKRRTESRPLP-NKLNAN 266 H+ ++P++C C F S L +HK IHTR K ++ K +S L +K+ Sbjct: 129 RIHTGQKPYKCEECGTSFYQFSYLTRHKLIHTREKPYKCEQYGKTFNQSSTLTGHKI--- 185 Query: 267 QGGFENGEIGESEENNPLDVHSIYIVPFQCPKCEKCFESEQILNEHSCF-----AARSGK 321 NGE P++C +C K F +H + R + Sbjct: 186 ---IHNGE-----------------KPYKCEECGKAFSIFSTPTKHKIIHTEEKSHRCEE 225 Query: 322 IPSRFKRSYNYKTIVKKILAKLKRARSKKLDNFQSEKKVFKKSFLRNCDLISGEQSSEQT 381 +K S ++ T K+I K + ++ S +F S L +I E+ S + Sbjct: 226 YCKAYKES-SHLTTHKRIHTGEKPYKCEECGKAFS---IF--STLTKHKIIHTEEKSHRC 279 Query: 382 QRTFVGSLGKHGTYKTIGNRKKKTLTLPFSWQNMGKNLK--GILTTENILSIDNSVNKKD 439 + G K ++ T +++ T P+ + GK ILT I+ + K Sbjct: 280 EEC--GKAYKESSHLTT-HKRIHTGEKPYKCEECGKTFSVFSILTKHKIIHTEEKPYK-- 334 Query: 440 LSICGSSGEEFFNNCEVLQCGFSVPRENIRTRHKIC-------PCDKCEKVFPSISKLKR 492 CE +CG + R + T+H+I C++C K F S L Sbjct: 335 --------------CE--ECGKAFKRSSTLTKHRIIHTEEKPYKCEECGKAFNQSSTLSI 378 Query: 493 HYLIHTGQRPFGCNICGKSFRQSAHLKRHEQTHNEKSPYASLCQVEFGNFNNLSNHSGNN 552 H +IHTG++P+ C CGK+F++S+ L H+ H + PY C+ E G N S+H + Sbjct: 379 HKIIHTGEKPYKCEECGKAFKRSSTLTIHKMIHTGEKPYK--CE-ECGKAFNRSSHLTTH 435 Query: 553 VNYNASQQCQAPGVQKYEVSESDQMSGVKAESQDFIPGSTGQPCLPNVLLESEQSNPFCS 612 + G + Y+ E + V F + Sbjct: 436 KRIHT-------GHKPYKCKECGKSFSV-----------------------------FST 459 Query: 613 YSEHQE-KNDVFLYRCSVCAKSFRSPSKLERHYLIHAGQKPFECSVCGKTFRQAPHWKRH 671 ++H+ D Y+C C K+F S L H IH G+KP++C CGK F+++ H H Sbjct: 460 LTKHKIIHTDKKPYKCEECGKAFNRSSILSIHKKIHTGEKPYKCEECGKAFKRSSHLAGH 519 Query: 672 QLTHFKERP 680 + H ++P Sbjct: 520 KQIHSVQKP 528 Score = 92.8 bits (229), Expect = 9e-19 Identities = 61/220 (27%), Positives = 96/220 (43%), Gaps = 19/220 (8%) Query: 479 KCEKVFPSISKLKRHYLIHTGQRPFGCNICGKSFRQSAHLKRHEQTHNEKSPYASLCQVE 538 +C K F S L H IHTGQ+P+ C CG SF Q ++L RH+ H + PY C+ Sbjct: 113 ECGKSFNQDSNLTTHKRIHTGQKPYKCEECGTSFYQFSYLTRHKLIHTREKPYK--CEQY 170 Query: 539 FGNFNNLSNHSGNNVNYNASQ--QCQAPGVQKYEVSESDQMSGVKAESQDFIPGSTGQPC 596 FN S +G+ + +N + +C+ G S + + E + C Sbjct: 171 GKTFNQSSTLTGHKIIHNGEKPYKCEECGKAFSIFSTPTKHKIIHTEEKS-------HRC 223 Query: 597 LPNVLLESEQSNPFCSYSEHQEKNDVFLYRCSVCAKSFRSPSKLERHYLIHAGQKPFECS 656 E S+ H + Y+C C K+F S L +H +IH +K C Sbjct: 224 EEYCKAYKESSHLTTHKRIHTGEKP---YKCEECGKAFSIFSTLTKHKIIHTEEKSHRCE 280 Query: 657 VCGKTFRQAPHWKRHQLTHFKERPQ-----GKVVALDSVM 691 CGK ++++ H H+ H E+P GK ++ S++ Sbjct: 281 ECGKAYKESSHLTTHKRIHTGEKPYKCEECGKTFSVFSIL 320 Score = 91.3 bits (225), Expect = 3e-18 Identities = 53/169 (31%), Positives = 81/169 (47%), Gaps = 11/169 (6%) Query: 25 RPYVCNICFKHFETPSKLARHYLIHTGQKPFECDVCHKTFRQLVHLERHQLTHSL--PFK 82 +PY C C K F S L+ H IHTG+KP++C+ C K F++ HL H+ HS+ P+K Sbjct: 471 KPYKCEECGKAFNRSSILSIHKKIHTGEKPYKCEECGKAFKRSSHLAGHKQIHSVQKPYK 530 Query: 83 CSICQRHFKNLKTFVKHQQLHNETYQNNVKQVRRLLEAKQEKSMYGVYNTFTTEERWALH 142 C C + F T KH+ +H E ++ + + + + +T E+ Sbjct: 531 CEECGKAFSIFSTLTKHKIIHTEEKPYKCEKCGKTFYRFSNLNTHKIIHT--GEKPCKCE 588 Query: 143 PCSKS-DPMYSMKRRKNIHA------CTICGKMFPSQSKLDRHVLIHTG 184 C K+ + ++ + K IH C CGK F S L RH +IH G Sbjct: 589 ECGKAFNHSSNLIKHKLIHTGDKPYKCEACGKAFRRSSHLSRHKIIHIG 637 Score = 33.1 bits (74), Expect = 0.88 Identities = 13/28 (46%), Positives = 17/28 (60%) Query: 24 NRPYVCNICFKHFETPSKLARHYLIHTG 51 ++PY C C K F S L+RH +IH G Sbjct: 610 DKPYKCEACGKAFRRSSHLSRHKIIHIG 637 >gi|115511044 zinc finger protein 493 isoform 3 [Homo sapiens] Length = 774 Score = 207 bits (526), Expect = 3e-53 Identities = 147/523 (28%), Positives = 241/523 (46%), Gaps = 44/523 (8%) Query: 25 RPYVCNICFKHFETPSKLARHYLIHTGQKPFECDVCHKTFRQLVHLERHQLTHS--LPFK 82 +PY C C F S L RH LIHT +KP++C+ KTF Q L H++ H+ P+K Sbjct: 263 KPYKCEECGTSFYQFSYLTRHKLIHTREKPYKCEQYGKTFNQSSTLTGHKIIHNGEKPYK 322 Query: 83 CSICQRHFKNLKTFVKHQQLHNETYQNNVKQVRRLLEAKQEKSMYGVYNTFTTEER-WAL 141 C C + F T KH+ +H E + ++ +A +E S + T E+ + Sbjct: 323 CEECGKAFSIFSTPTKHKIIHTEEKSHRCEEY---CKAYKESSHLTTHKRIHTGEKPYKC 379 Query: 142 HPCSKSDPMYSMKRRKNI-------HACTICGKMFPSQSKLDRHVLIHTGQRPFKCVLCT 194 C K+ ++S + I H C CGK + S L H IHTG++P+KC C Sbjct: 380 EECGKAFSIFSTLTKHKIIHTEEKSHRCEECGKAYKESSHLTTHKRIHTGEKPYKCEECG 439 Query: 195 KSFRQSTHLKIHQLTHSEERPFQCCFCQKGFKIQSKLLKHKQIHTRNKAFRALLLKKRRT 254 K+F + L H++ H+EE+P++C C K FK S L KH+ IHT K ++ K Sbjct: 440 KTFSVFSILTKHKIIHTEEKPYKCEECGKAFKRSSTLTKHRIIHTEEKPYKCEECGKAFN 499 Query: 255 ESRPLP--NKLNANQGGFENGEIGES-EENNPLDVHSIYIV---PFQCPKCEKCFESEQI 308 +S L ++ + ++ E G++ + ++ L +H + P++C +C K F Sbjct: 500 QSSTLSIHKIIHTGEKPYKCEECGKAFKRSSTLTIHKMIHTGEKPYKCEECGKAFNRSSH 559 Query: 309 LNEHSCFAARSGKIPSRFKRSYNYKTIVKKILAKLKRARSKKLDNFQSEKKVFKKSFLRN 368 L H +G P + K ++ + KK + K F +S + + Sbjct: 560 LTTHK--RIHTGHKPYKCKECGKSFSVFSTLTKHKIIHTDKKPYKCEECGKAFNRSSILS 617 Query: 369 CD--LISGEQSSEQTQRTFVGSLGKHGTYKTIGNRKKKTLTLPFSWQNMGK--NLKGILT 424 + +GE+ + + G K ++ G+++ ++ P+ + GK ++ LT Sbjct: 618 IHKKIHTGEKPYKCEE---CGKAFKRSSHLA-GHKQIHSVQKPYKCEECGKAFSIFSTLT 673 Query: 425 TENILSIDNSVNKKDLSICGSSGEEF--FNNCEVLQCGFSVPRENIRTRHKICPCDKCEK 482 I+ + K C G+ F F+N + I T K C C++C K Sbjct: 674 KHKIIHTEEKPYK-----CEKCGKTFYRFSNLNT--------HKIIHTGEKPCKCEECGK 720 Query: 483 VFPSISKLKRHYLIHTGQRPFGCNICGKSFRQSAHLKRHEQTH 525 F S L +H LIHTG +P+ C CGK+FR+S+HL RH+ H Sbjct: 721 AFNHSSNLIKHKLIHTGDKPYKCEACGKAFRRSSHLSRHKIIH 763 Score = 203 bits (517), Expect = 4e-52 Identities = 182/700 (26%), Positives = 286/700 (40%), Gaps = 133/700 (19%) Query: 23 RNRPYVCNICFKHFETPSKLARHYLIHTGQKPFECDVCHKTFRQLVHLERHQLTH--SLP 80 +++ + C+ K F RH HTG+KPF+C C K+F L+HL +H+ H Sbjct: 150 QSKIFQCDKYVKVFHKLLNSNRHNTKHTGKKPFKCKKCGKSFCMLLHLCQHKRIHIRENS 209 Query: 81 FKCSICQRHFKNLKTFVKHQQLHNETYQNNVKQVRRLLEAKQEKSMYGVYNTFTTEERWA 140 ++C C + F T +H+++H T E+ Sbjct: 210 YRCEECGKAFIWFSTLTRHRRVH-------------------------------TGEKSY 238 Query: 141 LHPCSKSDPMYS-MKRRKNIHA------CTICGKMFPSQSKLDRHVLIHTGQRPFKCVLC 193 + C KS S + K IH C CG F S L RH LIHT ++P+KC Sbjct: 239 KYECGKSFNQDSNLTTHKRIHTGQKPYKCEECGTSFYQFSYLTRHKLIHTREKPYKCEQY 298 Query: 194 TKSFRQSTHLKIHQLTHSEERPFQCCFCQKGFKIQSKLLKHKQIHTRNKAFRALLLKKRR 253 K+F QS+ L H++ H+ E+P++C C K F I S KHK IHT K+ R K Sbjct: 299 GKTFNQSSTLTGHKIIHNGEKPYKCEECGKAFSIFSTPTKHKIIHTEEKSHRCEEYCKAY 358 Query: 254 TESRPLP--NKLNANQGGFENGEIGES-EENNPLDVHSIYIV---PFQCPKCEKCFESEQ 307 ES L +++ + ++ E G++ + L H I +C +C K ++ Sbjct: 359 KESSHLTTHKRIHTGEKPYKCEECGKAFSIFSTLTKHKIIHTEEKSHRCEECGKAYKESS 418 Query: 308 ILNEHSCFAARSGKIPSRFK---RSYNYKTIVKKILAKLKRARSKKLDNFQSEKKVFKKS 364 L H +G+ P + + ++++ +I+ K K+ K + K + S Sbjct: 419 HLTTHK--RIHTGEKPYKCEECGKTFSVFSILTK--HKIIHTEEKPYKCEECGKAFKRSS 474 Query: 365 FLRNCDLISGEQ---SSEQTQRTFVGSLGKHGTYKTIGNRKKKTLTLPFSWQNMGKNLK- 420 L +I E+ E+ + F S +K I +K P+ + GK K Sbjct: 475 TLTKHRIIHTEEKPYKCEECGKAFNQS-STLSIHKIIHTGEK-----PYKCEECGKAFKR 528 Query: 421 -GILTTENILSIDNSVNKKDLSICGSSGEEFFNNCEVL---------------QCGFSVP 464 LT ++ K C G+ F + + +CG S Sbjct: 529 SSTLTIHKMIHTGEKPYK-----CEECGKAFNRSSHLTTHKRIHTGHKPYKCKECGKSFS 583 Query: 465 RENIRTRHKIC-------PCDKCEKVFPSISKLKRHYLIHTGQRPFGCNICGKSFRQSAH 517 + T+HKI C++C K F S L H IHTG++P+ C CGK+F++S+H Sbjct: 584 VFSTLTKHKIIHTDKKPYKCEECGKAFNRSSILSIHKKIHTGEKPYKCEECGKAFKRSSH 643 Query: 518 LKRHEQTHNEKSPY-ASLCQVEFGNFNNLSNHSGNNVNYNASQQCQAPGVQKYEVSESDQ 576 L H+Q H+ + PY C F F+ L+ H + +C+ G Y S + Sbjct: 644 LAGHKQIHSVQKPYKCEECGKAFSIFSTLTKHKIIHTE-EKPYKCEKCGKTFYRFSNLNT 702 Query: 577 MSGVKAESQDFIPGSTGQ-PCLPNVLLESEQSNPFCSYSEHQEKNDVFLYRCSVCAKSFR 635 + TG+ PC +C C K+F Sbjct: 703 HKII----------HTGEKPC-----------------------------KCEECGKAFN 723 Query: 636 SPSKLERHYLIHAGQKPFECSVCGKTFRQAPHWKRHQLTH 675 S L +H LIH G KP++C CGK FR++ H RH++ H Sbjct: 724 HSSNLIKHKLIHTGDKPYKCEACGKAFRRSSHLSRHKIIH 763 Score = 172 bits (435), Expect = 1e-42 Identities = 169/669 (25%), Positives = 264/669 (39%), Gaps = 160/669 (23%) Query: 30 NICFKHFETPSKLARHYLIHTGQKPFECDVCHKTFRQLVHLERHQLTHS--LPFKCSICQ 87 N C H E ++L YL T K F+CD K F +L++ RH H+ PFKC C Sbjct: 130 NECNVHKEGYNEL-NQYLTTTQSKIFQCDKYVKVFHKLLNSNRHNTKHTGKKPFKCKKCG 188 Query: 88 RHFKNLKTFVKHQQLHNETYQNNVKQVRRLLEAKQEKSMYGVYNTFTTEERWALHPCSKS 147 + F L LH C Sbjct: 189 KSFCML-----------------------------------------------LHLCQHK 201 Query: 148 DPMYSMKRRKNIHACTICGKMFPSQSKLDRHVLIHTGQRPFKCVLCTKSFRQSTHLKIHQ 207 + R+N + C CGK F S L RH +HTG++ +K C KSF Q ++L H+ Sbjct: 202 ----RIHIRENSYRCEECGKAFIWFSTLTRHRRVHTGEKSYKYE-CGKSFNQDSNLTTHK 256 Query: 208 LTHSEERPFQCCFCQKGFKIQSKLLKHKQIHTRNKAFRALLLKKRRTESRPLP-NKLNAN 266 H+ ++P++C C F S L +HK IHTR K ++ K +S L +K+ Sbjct: 257 RIHTGQKPYKCEECGTSFYQFSYLTRHKLIHTREKPYKCEQYGKTFNQSSTLTGHKI--- 313 Query: 267 QGGFENGEIGESEENNPLDVHSIYIVPFQCPKCEKCFESEQILNEHSCF-----AARSGK 321 NGE P++C +C K F +H + R + Sbjct: 314 ---IHNGE-----------------KPYKCEECGKAFSIFSTPTKHKIIHTEEKSHRCEE 353 Query: 322 IPSRFKRSYNYKTIVKKILAKLKRARSKKLDNFQSEKKVFKKSFLRNCDLISGEQSSEQT 381 +K S ++ T K+I K + ++ S +F S L +I E+ S + Sbjct: 354 YCKAYKES-SHLTTHKRIHTGEKPYKCEECGKAFS---IF--STLTKHKIIHTEEKSHRC 407 Query: 382 QRTFVGSLGKHGTYKTIGNRKKKTLTLPFSWQNMGKNLK--GILTTENILSIDNSVNKKD 439 + G K ++ T +++ T P+ + GK ILT I+ + K Sbjct: 408 EEC--GKAYKESSHLTT-HKRIHTGEKPYKCEECGKTFSVFSILTKHKIIHTEEKPYK-- 462 Query: 440 LSICGSSGEEFFNNCEVLQCGFSVPRENIRTRHKIC-------PCDKCEKVFPSISKLKR 492 CE +CG + R + T+H+I C++C K F S L Sbjct: 463 --------------CE--ECGKAFKRSSTLTKHRIIHTEEKPYKCEECGKAFNQSSTLSI 506 Query: 493 HYLIHTGQRPFGCNICGKSFRQSAHLKRHEQTHNEKSPYASLCQVEFGNFNNLSNHSGNN 552 H +IHTG++P+ C CGK+F++S+ L H+ H + PY C+ E G N S+H + Sbjct: 507 HKIIHTGEKPYKCEECGKAFKRSSTLTIHKMIHTGEKPYK--CE-ECGKAFNRSSHLTTH 563 Query: 553 VNYNASQQCQAPGVQKYEVSESDQMSGVKAESQDFIPGSTGQPCLPNVLLESEQSNPFCS 612 + G + Y+ E + V F + Sbjct: 564 KRIHT-------GHKPYKCKECGKSFSV-----------------------------FST 587 Query: 613 YSEHQE-KNDVFLYRCSVCAKSFRSPSKLERHYLIHAGQKPFECSVCGKTFRQAPHWKRH 671 ++H+ D Y+C C K+F S L H IH G+KP++C CGK F+++ H H Sbjct: 588 LTKHKIIHTDKKPYKCEECGKAFNRSSILSIHKKIHTGEKPYKCEECGKAFKRSSHLAGH 647 Query: 672 QLTHFKERP 680 + H ++P Sbjct: 648 KQIHSVQKP 656 Score = 92.8 bits (229), Expect = 9e-19 Identities = 61/220 (27%), Positives = 96/220 (43%), Gaps = 19/220 (8%) Query: 479 KCEKVFPSISKLKRHYLIHTGQRPFGCNICGKSFRQSAHLKRHEQTHNEKSPYASLCQVE 538 +C K F S L H IHTGQ+P+ C CG SF Q ++L RH+ H + PY C+ Sbjct: 241 ECGKSFNQDSNLTTHKRIHTGQKPYKCEECGTSFYQFSYLTRHKLIHTREKPYK--CEQY 298 Query: 539 FGNFNNLSNHSGNNVNYNASQ--QCQAPGVQKYEVSESDQMSGVKAESQDFIPGSTGQPC 596 FN S +G+ + +N + +C+ G S + + E + C Sbjct: 299 GKTFNQSSTLTGHKIIHNGEKPYKCEECGKAFSIFSTPTKHKIIHTEEKS-------HRC 351 Query: 597 LPNVLLESEQSNPFCSYSEHQEKNDVFLYRCSVCAKSFRSPSKLERHYLIHAGQKPFECS 656 E S+ H + Y+C C K+F S L +H +IH +K C Sbjct: 352 EEYCKAYKESSHLTTHKRIHTGEKP---YKCEECGKAFSIFSTLTKHKIIHTEEKSHRCE 408 Query: 657 VCGKTFRQAPHWKRHQLTHFKERPQ-----GKVVALDSVM 691 CGK ++++ H H+ H E+P GK ++ S++ Sbjct: 409 ECGKAYKESSHLTTHKRIHTGEKPYKCEECGKTFSVFSIL 448 Score = 91.3 bits (225), Expect = 3e-18 Identities = 53/169 (31%), Positives = 81/169 (47%), Gaps = 11/169 (6%) Query: 25 RPYVCNICFKHFETPSKLARHYLIHTGQKPFECDVCHKTFRQLVHLERHQLTHSL--PFK 82 +PY C C K F S L+ H IHTG+KP++C+ C K F++ HL H+ HS+ P+K Sbjct: 599 KPYKCEECGKAFNRSSILSIHKKIHTGEKPYKCEECGKAFKRSSHLAGHKQIHSVQKPYK 658 Query: 83 CSICQRHFKNLKTFVKHQQLHNETYQNNVKQVRRLLEAKQEKSMYGVYNTFTTEERWALH 142 C C + F T KH+ +H E ++ + + + + +T E+ Sbjct: 659 CEECGKAFSIFSTLTKHKIIHTEEKPYKCEKCGKTFYRFSNLNTHKIIHT--GEKPCKCE 716 Query: 143 PCSKS-DPMYSMKRRKNIHA------CTICGKMFPSQSKLDRHVLIHTG 184 C K+ + ++ + K IH C CGK F S L RH +IH G Sbjct: 717 ECGKAFNHSSNLIKHKLIHTGDKPYKCEACGKAFRRSSHLSRHKIIHIG 765 Score = 33.1 bits (74), Expect = 0.88 Identities = 13/28 (46%), Positives = 17/28 (60%) Query: 24 NRPYVCNICFKHFETPSKLARHYLIHTG 51 ++PY C C K F S L+RH +IH G Sbjct: 738 DKPYKCEACGKAFRRSSHLSRHKIIHIG 765 >gi|211057416 zinc finger protein 841 [Homo sapiens] Length = 924 Score = 206 bits (523), Expect = 8e-53 Identities = 178/677 (26%), Positives = 270/677 (39%), Gaps = 108/677 (15%) Query: 23 RNRPYVCNICFKHFETPSKLARHYLIHTGQKPFECDVCHKTFRQLVHLERHQLTHS--LP 80 R +PY C++C + F S L H HTG KP+ C+ C K+F + HL HQ H+ P Sbjct: 313 RGKPYQCDVCGRIFRQNSDLVNHRRSHTGDKPYICNECGKSFSKSSHLAVHQRIHTGEKP 372 Query: 81 FKCSICQRHFKNLKTFVKHQQLHNETYQNNVKQVRRLLEAKQEKSMYGVYNTFTTEERWA 140 +KC+ C + F + HQ +H + + K+ S+ + ++ + Sbjct: 373 YKCNRCGKCFSQSSSLATHQTVHTGDKPYKCNECGKTF--KRNSSLTAHHIIHAGKKPYT 430 Query: 141 LHPCSKSDPMYSMKRRKNI-------HACTICGKMFPSQSKLDRHVLIHTGQRPFKCVLC 193 C K S R I + C CGK+F +S+L H IHTG++P+KC C Sbjct: 431 CDVCGKVFYQNSQLVRHQIIHTGETPYKCNECGKVFFQRSRLAGHRRIHTGEKPYKCNEC 490 Query: 194 TKSFRQSTHLKIHQLTHSEERPFQCCFCQKGFKIQSKLLKHKQIHTRNKAFRALLLKKRR 253 K F Q +HL +HQ H+ E+P++C C K F S L H++IHT K ++ + K Sbjct: 491 GKVFSQHSHLAVHQRVHTGEKPYKCNECGKAFNWGSLLTVHQRIHTGEKPYKCNVCGKV- 549 Query: 254 TESRPLPNKLNANQGGFENGEIGESEENNPLDVHSIYIVPFQCPKCEKCFESEQILNEHS 313 N GG+ + + PL C KC F L H Sbjct: 550 -----------FNYGGYLSVHMRCHTGEKPL----------HCNKCGMVFTYYSCLARHQ 588 Query: 314 CFAARSGKIPSRFKRSYNYKTIVKKILAKLKRARSKKLDNFQSEK--KVFK--KSFLRNC 369 +G+ P +K + K + + R FQ + KVF R+ Sbjct: 589 --RMHTGEKP--YKCNVCGKVFIDSGNLSIHRRSHTGEKPFQCNECGKVFSYYSCLARHR 644 Query: 370 DLISGEQ-------SSEQTQRTFVGSLGKHGTYKTIGNRKKKTLTLPFSWQNMGKNLKGI 422 + +GE+ TQR+ SL KH T N P+ G+ Sbjct: 645 KIHTGEKPYKCNDCGKAYTQRS---SLTKHLVIHTGEN--------PYHCNEFGE---AF 690 Query: 423 LTTENILSIDNSVNKKDLSICGSSGEEFFNNCEVLQCGFSVPRENIRTRHKICPCDKCEK 482 + + + + + C G F + + V + T C +C K Sbjct: 691 IQSSKLARYHRNPTGEKPHKCSECGRTFSHKTSL------VYHQRRHTGEMPYKCIECGK 744 Query: 483 VFPSISKLKRHYLIHTGQRPFGCNICGKSFRQSAHLKRHEQTHNEKSPY-ASLCQVEFGN 541 VF S + L RH IHTG++P+ CN CGK FR + L RH H + PY + C F Sbjct: 745 VFNSTTTLARHRRIHTGEKPYKCNECGKVFRYRSGLARHWSIHTGEKPYKCNECGKAFRV 804 Query: 542 FNNLSNHSGNNVNYNASQQCQAPGVQKYEVSESDQMSGVKAESQDFIPGSTGQPCLPNVL 601 + L NH Q G + Y+ +E + FI Sbjct: 805 RSILLNH-----------QMMHTGEKPYKCNECGKA---------FI------------- 831 Query: 602 LESEQSNPFCSYSEHQEKNDVFLYRCSVCAKSFRSPSKLERHYLIHAGQKPFECSVCGKT 661 E+SN H + Y+C C K+F S L +H IH+ +KP++C+ CGK+ Sbjct: 832 ---ERSNLVYHQRNHTGEKP---YKCMECGKAFGRRSCLTKHQRIHSSEKPYKCNECGKS 885 Query: 662 FRQAPHWKRHQLTHFKE 678 + +HQ+ H E Sbjct: 886 YISRSGLTKHQIKHAGE 902 Score = 192 bits (488), Expect = 9e-49 Identities = 168/678 (24%), Positives = 279/678 (41%), Gaps = 78/678 (11%) Query: 23 RNRPYVCNICFKHFETPSKLARHYLIHTGQKPFECDVCHKTFRQLVHLERHQLTHSL--P 80 R +PY+ N C K F S L H +IHT +KP+ C+ K F + L HQ+ H+ P Sbjct: 257 REKPYIGNECGKAFRVSSSLINHQMIHTTEKPYRCNESGKAFHRGSLLTVHQIVHTRGKP 316 Query: 81 FKCSICQRHFKNLKTFVKHQQLHNETYQNNVKQVRRLLEAKQEKSMYGVYNTFTTEERWA 140 ++C +C R F+ V H++ H + + +++ T E+ + Sbjct: 317 YQCDVCGRIFRQNSDLVNHRRSHTGDKPYICNECGKSFSKSSHLAVH--QRIHTGEKPYK 374 Query: 141 LHPCSKS-DPMYSMKRRKNIHA------CTICGKMFPSQSKLDRHVLIHTGQRPFKCVLC 193 + C K S+ + +H C CGK F S L H +IH G++P+ C +C Sbjct: 375 CNRCGKCFSQSSSLATHQTVHTGDKPYKCNECGKTFKRNSSLTAHHIIHAGKKPYTCDVC 434 Query: 194 TKSFRQSTHLKIHQLTHSEERPFQCCFCQKGFKIQSKLLKHKQIHTRNKAFRALLLKKRR 253 K F Q++ L HQ+ H+ E P++C C K F +S+L H++IHT K ++ K Sbjct: 435 GKVFYQNSQLVRHQIIHTGETPYKCNECGKVFFQRSRLAGHRRIHTGEKPYKCNECGKVF 494 Query: 254 TESRPLP--NKLNANQGGFENGEIGESEE-NNPLDVHSIYIV---PFQCPKCEKCFESEQ 307 ++ L +++ + ++ E G++ + L VH P++C C K F Sbjct: 495 SQHSHLAVHQRVHTGEKPYKCNECGKAFNWGSLLTVHQRIHTGEKPYKCNVCGKVFNYGG 554 Query: 308 ILNEHSCFAARSGKIPSRFKRSYNYKTIVKKILAKLKRARSKKLDNFQSEKK--VFKKSF 365 L+ H +G+ P + T + AR +++ + K V K F Sbjct: 555 YLSVH--MRCHTGEKPLHCNKCGMVFTYYSCL------ARHQRMHTGEKPYKCNVCGKVF 606 Query: 366 LRNCDLISGEQSSEQTQRTFVGSLGKHGTYKTIGNRKKKTLT--LPFSWQNMGKNLKGIL 423 + + +L +S + GK +Y + R +K T P+ + GK Sbjct: 607 IDSGNLSIHRRSHTGEKPFQCNECGKVFSYYSCLARHRKIHTGEKPYKCNDCGKAYTQRS 666 Query: 424 TTENILSIDNSVNKKDLSICGSSGEEFFNNCEVLQCGFSVPRENIRTRHKICPCDKCEKV 483 + L I N C GE F + ++ + + E HK C +C + Sbjct: 667 SLTKHLVIHTGENPYH---CNEFGEAFIQSSKLARYHRNPTGEK---PHK---CSECGRT 717 Query: 484 FPSISKLKRHYLIHTGQRPFGCNICGKSFRQSAHLKRHEQTHNEKSPY-ASLCQVEFGNF 542 F + L H HTG+ P+ C CGK F + L RH + H + PY + C F Sbjct: 718 FSHKTSLVYHQRRHTGEMPYKCIECGKVFNSTTTLARHRRIHTGEKPYKCNECGKVFRYR 777 Query: 543 NNLSNHSGNNVNYNASQQCQAPGVQKYEVSESDQMSGVKAESQDFIPGSTGQPCLPNVLL 602 + L+ H + G + Y+ +E + V++ +LL Sbjct: 778 SGLARHWSIHT-----------GEKPYKCNECGKAFRVRS-----------------ILL 809 Query: 603 ESEQSNPFCSYSEHQEKNDVFLYRCSVCAKSFRSPSKLERHYLIHAGQKPFECSVCGKTF 662 + + EK Y+C+ C K+F S L H H G+KP++C CGK F Sbjct: 810 NHQMMHT-------GEKP----YKCNECGKAFIERSNLVYHQRNHTGEKPYKCMECGKAF 858 Query: 663 RQAPHWKRHQLTHFKERP 680 + +HQ H E+P Sbjct: 859 GRRSCLTKHQRIHSSEKP 876 Score = 166 bits (420), Expect = 7e-41 Identities = 165/688 (23%), Positives = 273/688 (39%), Gaps = 100/688 (14%) Query: 12 IQQCVVANKLPRNRPYV-CNICFKH---FETPSKLARHYLIHTGQKPFECDVCHKTFRQL 67 + C +A+ L R P V NI K+ F S + H +KP+ + C K FR Sbjct: 214 VNNCFLASPLQRIFPGVQTNISRKYGNDFLQLSLPTQDEKTHIREKPYIGNECGKAFRVS 273 Query: 68 VHLERHQLTHSL--PFKCSICQRHFKNLKTFVKHQQLHNETYQNNVKQVRRLLEAKQEKS 125 L HQ+ H+ P++C+ + F HQ +H Sbjct: 274 SSLINHQMIHTTEKPYRCNESGKAFHRGSLLTVHQIVHT--------------------- 312 Query: 126 MYGVYNTFTTEERWALHPCSKSDPMYSMKRRKNIHACTICGKMFPSQSKLDRHVLIHTGQ 185 R + C +CG++F S L H HTG Sbjct: 313 ------------------------------RGKPYQCDVCGRIFRQNSDLVNHRRSHTGD 342 Query: 186 RPFKCVLCTKSFRQSTHLKIHQLTHSEERPFQCCFCQKGFKIQSKLLKHKQIHTRNKAFR 245 +P+ C C KSF +S+HL +HQ H+ E+P++C C K F S L H+ +HT +K ++ Sbjct: 343 KPYICNECGKSFSKSSHLAVHQRIHTGEKPYKCNRCGKCFSQSSSLATHQTVHTGDKPYK 402 Query: 246 ALLLKK--RRTESRPLPNKLNANQGGFENGEIGES-EENNPLDVHSIYIV---PFQCPKC 299 K +R S + ++A + + G+ +N+ L H I P++C +C Sbjct: 403 CNECGKTFKRNSSLTAHHIIHAGKKPYTCDVCGKVFYQNSQLVRHQIIHTGETPYKCNEC 462 Query: 300 EKCFESEQILNEHSCFAARSGKIPSRFKRSYNYKTIVKKILAKLKRARSKKLDNFQSEKK 359 K F L H +G+ P + + + + +K K Sbjct: 463 GKVFFQRSRLAGHR--RIHTGEKPYKCNECGKVFSQHSHLAVHQRVHTGEKPYKCNECGK 520 Query: 360 VFKKSFLRNCDLISGEQSSEQTQRTF----VGSLGKHGTYKTIGNRKKKTLTLPFSWQNM 415 F L++ Q ++ + G + +G Y ++ + + T P Sbjct: 521 AFNWG-----SLLTVHQRIHTGEKPYKCNVCGKVFNYGGYLSV-HMRCHTGEKPLHCNKC 574 Query: 416 GKNLKGILTTENILSIDNSVNKKDLSI-CGSSGEEFFNNCEVLQCGFSVPRENIRTRHKI 474 G + T + L+ ++ + C G+ F ++ + S+ R + T K Sbjct: 575 GM----VFTYYSCLARHQRMHTGEKPYKCNVCGKVFIDSGNL-----SIHRRS-HTGEKP 624 Query: 475 CPCDKCEKVFPSISKLKRHYLIHTGQRPFGCNICGKSFRQSAHLKRHEQTHNEKSPYASL 534 C++C KVF S L RH IHTG++P+ CN CGK++ Q + L +H H ++PY Sbjct: 625 FQCNECGKVFSYYSCLARHRKIHTGEKPYKCNDCGKAYTQRSSLTKHLVIHTGENPY--- 681 Query: 535 CQVEFGNFNNLSNHSGNNVNYNASQQCQAPGVQKYEVSESDQMSGVKAESQDFIPGSTGQ 594 F S Y+ + + P ++ SE + K TG+ Sbjct: 682 ---HCNEFGEAFIQSSKLARYHRNPTGEKP----HKCSECGRTFSHKTSLVYHQRRHTGE 734 Query: 595 PCLPNVLLE-SEQSNPFCSYSEHQE-KNDVFLYRCSVCAKSFRSPSKLERHYLIHAGQKP 652 +P +E + N + + H+ Y+C+ C K FR S L RH+ IH G+KP Sbjct: 735 --MPYKCIECGKVFNSTTTLARHRRIHTGEKPYKCNECGKVFRYRSGLARHWSIHTGEKP 792 Query: 653 FECSVCGKTFRQAPHWKRHQLTHFKERP 680 ++C+ CGK FR HQ+ H E+P Sbjct: 793 YKCNECGKAFRVRSILLNHQMMHTGEKP 820 >gi|47271464 zinc finger protein 607 [Homo sapiens] Length = 696 Score = 206 bits (523), Expect = 8e-53 Identities = 176/691 (25%), Positives = 288/691 (41%), Gaps = 97/691 (14%) Query: 1 MMAENNLKMLKIQQCVVANKLPRN--RPYVCNICFKHFETPSKLARHYLIHTGQKPFECD 58 ++++ +++ + CV ++ N +PY C C K F ++L H IHT ++P +C+ Sbjct: 86 IISDGKMQLYRKHSCVTLHQRIHNGQKPYECKQCQKSFSHLTELMVHQTIHTSEEPDQCE 145 Query: 59 VCHKTFRQLVHLERHQLTHSL--PFKCSICQRHFKNLKTFVKHQQLHNETYQNNVKQVRR 116 K F L L +HQ ++ P++C C + F +H ++H V + Sbjct: 146 KFRKAFSHLTDLRKHQKINAREKPYECEECGKVFSYPANLAQHGKVH----------VEK 195 Query: 117 LLEAKQEKSMYGVYNTFTTEERWALHPCSKSDPMYSMKRRKNIHACTICGKMFPSQSKLD 176 E K+ + T R+ Y K + C CGK F +L Sbjct: 196 PYECKECGEAFRTSRQLTVHHRFH----------YGEKP----YECKECGKAFSVYGRLS 241 Query: 177 RHVLIHTGQRPFKCVLCTKSFRQSTHLKIHQLTHSEERPFQCCFCQKGFKIQSKLLKHKQ 236 RH IHTG++PF+C C KSFR LK+HQ H+ E+P +C C K F+ S L+ HK+ Sbjct: 242 RHQSIHTGEKPFECNKCGKSFRLKAGLKVHQSIHTGEKPHECKECGKAFRQFSHLVGHKR 301 Query: 237 IHTRNKAFRALLLKKRRT--ESRPLPNKLNANQGGFENGEIGE--SEENNPLDVHSIYIV 292 IHT K + K T + ++ + + +E E GE S + H+ V Sbjct: 302 IHTGEKPYECKECGKGFTCRYQLTMHQRIYSGEKHYECKENGEAFSSGHQLTAPHTFESV 361 Query: 293 --PFQCPKCEKCFESEQILNEHSCFAARSGKIP---SRFKRSYNYKTIVKKILAKLKRAR 347 P++C +C K F L H SGK P ++ +S+ + + Sbjct: 362 EKPYKCEECGKAFSVHGRLTRHQ--GIHSGKKPYECNKCGKSFRLNSSL----------- 408 Query: 348 SKKLDNFQSEKKVFKKSFLRNCDLISGEQSSEQTQRTFVGSLGKHGTYKTIGNRKKKTLT 407 K N + +K +K + C G+ S++ + H YK Sbjct: 409 -KIHQNIHTGEKPYK---CKEC----GKAFSQRAHLAHHNRI--HTGYK----------- 447 Query: 408 LPFSWQNMGKNLKGILTTENILSIDNSVNKKDLS-ICGSSGEEFFNNCEVLQCGFSVPRE 466 PF + GK+ + + L I ++ + +C G+ F + ++ Sbjct: 448 -PFECKECGKSFR----CASYLVIHERIHTGEKPYVCQECGKGFSYSHKL------TIHR 496 Query: 467 NIRTRHKICPCDKCEKVFPSISKLKRHYLIHTGQRPFGCNICGKSFRQSAHLKRHEQTHN 526 + T K C +C K F +L +H IH+G+RPF CN CGKSFR + LK H+ H+ Sbjct: 497 RVHTGEKPYECKECGKAFSVSGQLTQHLSIHSGKRPFECNKCGKSFRFISVLKAHQNIHS 556 Query: 527 EKSPY-ASLCQVEFGNFNNLSNHSGNNVNYNASQQCQAPGVQKYEVSESDQMSGVKAESQ 585 + PY C F + +L H + S +C+ G S + + Sbjct: 557 AEKPYECKECGKAFRHATSLIYHDRTHAG-EKSYECKECGETFSHASHLIIHERIHTSDK 615 Query: 586 DFIPGSTGQPC-LPNVLLESEQSNPFCSYSEHQEKNDVFLYRCSVCAKSFRSPSKLERHY 644 + G+ + L+ E S H + N Y C C K+F S +L H+ Sbjct: 616 PYECKRCGKAFHCASYLVRHE--------SVHADGNP---YMCEECGKAFNSSHELSIHH 664 Query: 645 LIHAGQKPFECSVCGKTFRQAPHWKRHQLTH 675 +H G+KPF+C+ C ++FR + HQ H Sbjct: 665 RVHTGEKPFKCNKCRRSFRLRSILEVHQRIH 695 Score = 160 bits (405), Expect = 4e-39 Identities = 151/615 (24%), Positives = 240/615 (39%), Gaps = 109/615 (17%) Query: 73 HQLTHS--LPFKCSICQRHFKNLKTFVKHQQLHNETYQNNVKQVRRLLEAKQEKSMYGVY 130 HQ H+ P++C CQ+ F +L + HQ +H + ++ R+ + + Sbjct: 104 HQRIHNGQKPYECKQCQKSFSHLTELMVHQTIHTSEEPDQCEKFRKAFSHLTDLRKHQKI 163 Query: 131 NTFTTEERWALHPCSKSDPMYSMKRRKNIHACTICGKMFPSQSKLDRHVLIHTGQRPFKC 190 N R+ + C CGK+F + L +H +H ++P++C Sbjct: 164 NA-----------------------REKPYECEECGKVFSYPANLAQHGKVHV-EKPYEC 199 Query: 191 VLCTKSFRQSTHLKIHQLTHSEERPFQCCFCQKGFKIQSKLLKHKQIHTRNKAFRALLLK 250 C ++FR S L +H H E+P++C C K F + +L +H+ IHT K F Sbjct: 200 KECGEAFRTSRQLTVHHRFHYGEKPYECKECGKAFSVYGRLSRHQSIHTGEKPFECNKCG 259 Query: 251 KRRTESRPLPNKLNANQGGFENGEIGESEENNPLDVHSIYIVPFQCPKCEKCFESEQILN 310 K +L A ++ GE P +C +C K F L Sbjct: 260 KSF--------RLKAGLKVHQSIHTGEK--------------PHECKECGKAFRQFSHLV 297 Query: 311 EHSCFAARSGKIPSRFKRSYNYKTIVKKILAKLKRARSKKLDNFQSEKKVFKKSFLRNCD 370 H +G+ P Y K K + + +++ + EK K Sbjct: 298 GHK--RIHTGEKP------YECKECGKGFTCRYQLTMHQRI--YSGEKHYECKE------ 341 Query: 371 LISGEQSSEQTQRTFVGSLGKHGTYKTIGNRKKKTLTLPFSWQNMGK--NLKGILTTENI 428 +GE S Q T H T++++ P+ + GK ++ G LT Sbjct: 342 --NGEAFSSGHQLT-----APH-TFESVEK--------PYKCEECGKAFSVHGRLTRHQ- 384 Query: 429 LSIDNSVNKKDLSICGSSGEEFFNNCEVLQCGFSVPRENIRTRHKICPCDKCEKVFPSIS 488 I + + + CG S L + +NI T K C +C K F + Sbjct: 385 -GIHSGKKPYECNKCGKSFR--------LNSSLKI-HQNIHTGEKPYKCKECGKAFSQRA 434 Query: 489 KLKRHYLIHTGQRPFGCNICGKSFRQSAHLKRHEQTHNEKSPYASL-CQVEFGNFNNLSN 547 L H IHTG +PF C CGKSFR +++L HE+ H + PY C F + L+ Sbjct: 435 HLAHHNRIHTGYKPFECKECGKSFRCASYLVIHERIHTGEKPYVCQECGKGFSYSHKLTI 494 Query: 548 HSGNNVNYNASQQCQAPGVQKYEVSESDQMSGVKAESQDFIPGSTGQPCLPNVLLESEQS 607 H + G + YE E + V + + +G+ P + +S Sbjct: 495 HRRVHT-----------GEKPYECKECGKAFSVSGQLTQHLSIHSGKR--PFECNKCGKS 541 Query: 608 NPFCSYSE-HQEKNDVFL-YRCSVCAKSFRSPSKLERHYLIHAGQKPFECSVCGKTFRQA 665 F S + HQ + Y C C K+FR + L H HAG+K +EC CG+TF A Sbjct: 542 FRFISVLKAHQNIHSAEKPYECKECGKAFRHATSLIYHDRTHAGEKSYECKECGETFSHA 601 Query: 666 PHWKRHQLTHFKERP 680 H H+ H ++P Sbjct: 602 SHLIIHERIHTSDKP 616 Score = 42.4 bits (98), Expect = 0.001 Identities = 21/59 (35%), Positives = 27/59 (45%), Gaps = 4/59 (6%) Query: 626 RCSVCAKS----FRSPSKLERHYLIHAGQKPFECSVCGKTFRQAPHWKRHQLTHFKERP 680 RC + + +R S + H IH GQKP+EC C K+F HQ H E P Sbjct: 83 RCEIISDGKMQLYRKHSCVTLHQRIHNGQKPYECKQCQKSFSHLTELMVHQTIHTSEEP 141 >gi|222418585 zinc finger protein 814 [Homo sapiens] Length = 855 Score = 203 bits (516), Expect = 5e-52 Identities = 176/681 (25%), Positives = 273/681 (40%), Gaps = 86/681 (12%) Query: 21 LPRNRPYVCNICFKHFETPSKLARHYLIHTGQKPFECDVCHKTFRQLVHLERHQLTHS-L 79 L R YVC C K F + L+ H +HT +K EC C K+F + V HQ H+ Sbjct: 236 LTREECYVCCECGKSFSKYASLSNHQRVHT-EKKHECGECGKSFSKYVSFSNHQRVHTEK 294 Query: 80 PFKCSICQRHFKNLKTFVKHQQLHNETYQNNVKQVRRLLEAKQEKSMYGVYNTFTTEERW 139 +C C + F +F HQ++H +R E + + Y +F+ +R Sbjct: 295 KHECGECGKSFSKYVSFSNHQRVHTG---------KRPYECGECGKSFSKYASFSNHQR- 344 Query: 140 ALHPCSKSDPMYSMKRRKNIHACTICGKMFPSQSKLDRHVLIHTGQRPFKCVLCTKSFRQ 199 + K + C CGK F H +HTG+RP++C C KSF + Sbjct: 345 -------------VHTEKKHYECGECGKSFSKYVSFSNHQRVHTGKRPYECGECGKSFSK 391 Query: 200 STHLKIHQLTHSEERPFQCCFCQKGFKIQSKLLKHKQIHTRNKAFRALLLKKRRTESRPL 259 HQ H++++ ++C C K F +S L++H++ HT K + K + L Sbjct: 392 YASFSNHQRVHTDKKHYECGECGKSFSQKSSLIQHQRFHTGEKPYGCEECGKSFSSEGHL 451 Query: 260 PN--KLNANQGGFENGEIGESEENNPLDVHSIYIV----PFQCPKCEKCFESEQILNEHS 313 + +++A + F+ GE +S + VH + P+QC +C K F + L H Sbjct: 452 RSHQRVHAGERPFKCGECVKSFSHKRSLVHHQRVHSGERPYQCGECGKSFSQKGNLVLHQ 511 Query: 314 CFAARSGKIPSRFKRSYNYKTIVKKILAK--LKRARSKKLDNFQSEKKVFKKSFLRNCDL 371 +G P Y K +K L+ + + E KSF L Sbjct: 512 --RVHTGARP------YECGECGKSFSSKGHLRNHQQIHTGDRLYECGECGKSFSHKGTL 563 Query: 372 ISGEQSSEQTQRTFVGSLGKHGTYKTIGN----RKKKTLTLPFSWQNMGKNL--KGILTT 425 I ++ + + G GK ++ +IG+ ++ T P+ GK+ K L Sbjct: 564 ILHQRVHPRERSYGCGECGK--SFSSIGHLRSHQRVHTGERPYECGECGKSFSHKRSLVH 621 Query: 426 ENILSIDNSVNKKDLSICGSSGEEFFNNCEVLQCGFSVPRENIRTRHKICPCDKCEKVFP 485 + K CG G+ F G + + T + C +C K F Sbjct: 622 HQRMHTGERPYK-----CGDCGKSFNEK------GHLRNHQRVHTTERPFKCGECGKCFS 670 Query: 486 SISKLKRHYLIHTGQRPFGCNICGKSFRQSAHLKRHEQTHNEKSPYA-SLCQVEFGNFNN 544 L H HTG+RP+ C CGK F++ +HL H++ HN + PYA CQ F N Sbjct: 671 HKGNLILHQHGHTGERPYVCRECGKLFKKKSHLLVHQRIHNGEKPYACEACQKFFRNKYQ 730 Query: 545 LSNHSGNNVNYNASQQCQAPGVQKYEVSESDQM---SGVKAESQDFIPGSTGQPCLPNVL 601 L H Q G + YE ++ + S + G C Sbjct: 731 LIAH-----------QRVHTGERPYECNDCGKSFTHSSTFCVHKRIHTGEKPYEC----- 774 Query: 602 LESEQSNPFCSYSEHQEKNDVFL----YRCSVCAKSFRSPSKLERHYLIHAGQKPFECSV 657 SE F S + V Y CS C KSF S L +H +H G+KP++C Sbjct: 775 --SECGKSFAESSSFTKHKRVHTGEKPYECSECGKSFAESSSLTKHKRVHTGEKPYKCEK 832 Query: 658 CGKTFRQAPHWKRHQLTHFKE 678 CGK F + H HQ +H+++ Sbjct: 833 CGKLFNKKSHLLVHQSSHWRK 853 Score = 150 bits (380), Expect = 3e-36 Identities = 158/718 (22%), Positives = 272/718 (37%), Gaps = 124/718 (17%) Query: 52 QKPFECDVCHKTFRQLVHLERHQLTHSLP--FKCSICQRHFKNLKTFVKHQQLH--NETY 107 +K C++C ++H+ HQ TH +C + F +HQ H + Y Sbjct: 89 KKAHPCEMCGPILGDILHVADHQGTHHKQKLHRCEAWGNKLYDSGNFHQHQNEHIGEKPY 148 Query: 108 QNNVKQVRRLLEAK-------------------------QEKSMYGVYNTFTTE------ 136 + +V++ K QE S G + TE Sbjct: 149 RGSVEEALFAKRCKLHVSGESSVFSESGKDFLPRSGLLQQEASHTGEKSNSKTECVSPIQ 208 Query: 137 ERWALHPCSKSDPMYSMKR----------RKNIHACTICGKMFPSQSKLDRHVLIHT--- 183 A + C +S +S K R+ + C CGK F + L H +HT Sbjct: 209 CGGAHYSCGESMKHFSTKHILSQHQRLLTREECYVCCECGKSFSKYASLSNHQRVHTEKK 268 Query: 184 -----------------------GQRPFKCVLCTKSFRQSTHLKIHQLTHSEERPFQCCF 220 ++ +C C KSF + HQ H+ +RP++C Sbjct: 269 HECGECGKSFSKYVSFSNHQRVHTEKKHECGECGKSFSKYVSFSNHQRVHTGKRPYECGE 328 Query: 221 CQKGFKIQSKLLKHKQIHTRNKAFRALLLKKRRTESRPLPN--KLNANQGGFENGEIGES 278 C K F + H+++HT K + K ++ N +++ + +E GE G+S Sbjct: 329 CGKSFSKYASFSNHQRVHTEKKHYECGECGKSFSKYVSFSNHQRVHTGKRPYECGECGKS 388 Query: 279 -----EENNPLDVHSIYIVPFQCPKCEKCFESEQILNEHSCFAARSGKIPSRFKRSYNYK 333 +N VH+ ++C +C K F + L +H F +G+ P Y + Sbjct: 389 FSKYASFSNHQRVHTDK-KHYECGECGKSFSQKSSLIQHQRF--HTGEKP------YGCE 439 Query: 334 TIVKKILAKLKRARSKKLDNFQSEKKVFK-----KSFLRNCDLISGEQSSEQTQRTFVGS 388 K ++ + + ++ FK KSF L+ ++ + G Sbjct: 440 ECGKSFSSE---GHLRSHQRVHAGERPFKCGECVKSFSHKRSLVHHQRVHSGERPYQCGE 496 Query: 389 LGKHGTYK--TIGNRKKKTLTLPFSWQNMGKNLKGILTTENILSIDNSVNKKD-LSICGS 445 GK + K + +++ T P+ GK+ +++ L ++ D L CG Sbjct: 497 CGKSFSQKGNLVLHQRVHTGARPYECGECGKS----FSSKGHLRNHQQIHTGDRLYECGE 552 Query: 446 SGEEFFNNCEVLQCGFSVPRENIRTRHKICPCDKCEKVFPSISKLKRHYLIHTGQRPFGC 505 G+ F + G + + + R + C +C K F SI L+ H +HTG+RP+ C Sbjct: 553 CGKSFSHK------GTLILHQRVHPRERSYGCGECGKSFSSIGHLRSHQRVHTGERPYEC 606 Query: 506 NICGKSFRQSAHLKRHEQTHNEKSPYASLCQVEFGNFNNLSNHSGNNVNYNASQQCQAPG 565 CGKSF L H++ H + PY + G+ N G+ N+ + P Sbjct: 607 GECGKSFSHKRSLVHHQRMHTGERPY------KCGDCGKSFNEKGHLRNHQRVHTTERP- 659 Query: 566 VQKYEVSESDQMSGVKAESQDFIPGSTGQ---PCLPNVLLESEQSNPFCSYSEHQEKNDV 622 ++ E + K G TG+ C L ++S+ H + Sbjct: 660 ---FKCGECGKCFSHKGNLILHQHGHTGERPYVCRECGKLFKKKSHLLVHQRIHNGEKP- 715 Query: 623 FLYRCSVCAKSFRSPSKLERHYLIHAGQKPFECSVCGKTFRQAPHWKRHQLTHFKERP 680 Y C C K FR+ +L H +H G++P+EC+ CGK+F + + H+ H E+P Sbjct: 716 --YACEACQKFFRNKYQLIAHQRVHTGERPYECNDCGKSFTHSSTFCVHKRIHTGEKP 771 Score = 94.0 bits (232), Expect = 4e-19 Identities = 62/241 (25%), Positives = 95/241 (39%), Gaps = 20/241 (8%) Query: 443 CGSSGEEFFNNCEVLQCGFSVPRENIRTRHKICPCDKCEKVFPSISKLKRHYLIHTGQRP 502 CG S + F + Q + + TR + C +C K F + L H +HT ++ Sbjct: 216 CGESMKHFSTKHILSQ------HQRLLTREECYVCCECGKSFSKYASLSNHQRVHT-EKK 268 Query: 503 FGCNICGKSFRQSAHLKRHEQTHNEKSPYASLCQVEFGNFNNLSNHSGNNVNYNASQQCQ 562 C CGKSF + H++ H EK C F + + SNH + +C Sbjct: 269 HECGECGKSFSKYVSFSNHQRVHTEKKHECGECGKSFSKYVSFSNHQRVHTG-KRPYECG 327 Query: 563 APGVQKYEVSESDQMSGVKAESQDFIPGSTGQPCLPNVLLESEQSNPFCSYSEHQEKNDV 622 G + + V E + + G G+ + + S+S HQ + Sbjct: 328 ECGKSFSKYASFSNHQRVHTEKKHYECGECGK-----------SFSKYVSFSNHQRVHTG 376 Query: 623 FL-YRCSVCAKSFRSPSKLERHYLIHAGQKPFECSVCGKTFRQAPHWKRHQLTHFKERPQ 681 Y C C KSF + H +H +K +EC CGK+F Q +HQ H E+P Sbjct: 377 KRPYECGECGKSFSKYASFSNHQRVHTDKKHYECGECGKSFSQKSSLIQHQRFHTGEKPY 436 Query: 682 G 682 G Sbjct: 437 G 437 >gi|62243640 zinc finger protein 107 [Homo sapiens] Length = 783 Score = 202 bits (515), Expect = 6e-52 Identities = 186/707 (26%), Positives = 297/707 (42%), Gaps = 108/707 (15%) Query: 23 RNRPYVCNICFKHFETPSKLARHYLIHTGQKPFECDVCHKTFRQLVHLERHQLTHS--LP 80 R Y C C K F S L +H IHTG+KP++C+ C K F Q L RH++ H+ P Sbjct: 128 RVNSYKCEECGKAFNWFSTLTKHKRIHTGEKPYKCEECGKAFNQSSQLTRHKIIHTEEKP 187 Query: 81 FKCSICQRHFKNLKTFVKHQQLHNETYQNNVKQVRRLLEAKQEKSMYGVYNTFTTEERWA 140 KC C + FK H+ +H ++ ++ + + +T E + Sbjct: 188 NKCEECGKAFKQASHLTIHKIIHTGEKPYKYEECGKVFSQSSHLTTQKILHT--GENLYK 245 Query: 141 LHPCSKSDPMYS-MKRRKNIHA------CTICGKMFPSQSKLDRHVLIHTGQRPFKCVLC 193 C K+ ++S + K IHA C CG+ F S L++ IHTG + KC C Sbjct: 246 CKECGKAFNLFSNLTNHKRIHAGEKPYKCKECGRAFNISSNLNKQEKIHTGGKLNKCEEC 305 Query: 194 TKSFRQSTHLKIHQLTHSEERPFQCCFCQKGFKIQSKLLKHKQIHTRNKAFRALLLKKRR 253 K+F +S L H+ EE+P++C C K F S L +HK IHT K ++ K Sbjct: 306 DKAFNRSLKLTAHKKILMEEKPYKCEECGKVFNQFSTLTRHKIIHTGEKPYKCKECGKAF 365 Query: 254 TESRPLPN--KLNANQGGFENGEIGES--EENNPLDVHSIYI--VPFQCPKCEKCFESEQ 307 +S L K++ + ++ E G++ + +N ++ IY P++C +C K F Sbjct: 366 NQSSNLTEHKKIHTAEKSYKCEECGKAFNQHSNLINHRKIYSGEKPYKCEECGKAFNRSS 425 Query: 308 ILNEHSCFAARSGKIPSR-------FKRSYNYKTIVKKI--------------------- 339 L H +G+ P + F +S N T KKI Sbjct: 426 TLTRHK--KIHTGEKPYKCEECDRAFSQSSNL-TEHKKIHTGEKPYKCEECGKAFNRFST 482 Query: 340 LAKLKRARS-KKLDNFQSEKKVFKKSF-LRNCDLISGEQSSEQTQRTFVGSLGKHGTYKT 397 L K KR + +K + K F +S+ L ++ ++ + + G K +++T Sbjct: 483 LTKHKRIHTGEKPYKCEECGKAFNQSYQLTRHKIVHTKEKLNKCEE--FGKAFKQSSHRT 540 Query: 398 IGNRKKKTLTLPFSWQNMGK--NLKGILTTENILSIDNSVNKKDLSICGSSGEEF--FNN 453 I ++ T P+ + GK N LTT+ I+ ++ K + G+ F F+N Sbjct: 541 I-HKIIHTGEKPYKCEEHGKVFNQSSNLTTQKIIHTGENLYKFE-----EHGKAFNLFSN 594 Query: 454 CEVLQCGFSVPRENIRTRHKICPCDKCEKVFPSISKLKRHYLIHTGQRPFGCNICGKSFR 513 + I T K C++C K + S L H IHTG++P+ C CGK+F Sbjct: 595 I--------TNHKIIYTGEKPHKCEECGKAYNRFSNLTIHKRIHTGEKPYQCAECGKAFN 646 Query: 514 QSAHLKRHEQTHNEKSPYASLCQVEFGNFNNLSNHSGNNVNYNASQQCQAPGVQKYEVSE 573 S+ L RH+ H + PY C+ E G NLS+ A ++ G + Y+ E Sbjct: 647 CSSTLNRHKIIHTGEKPYK--CK-ECGKAFNLSS------TLTAHKKIHT-GEKPYKCEE 696 Query: 574 SDQMSGVKAESQDFIPGSTGQPCLPNVLLESEQSNPFCSYSEHQEKNDVFLYRCSVCAKS 633 + ++ SN H + Y+C C KS Sbjct: 697 CGKAF-------------------------NQSSNLTTHKKIHTSEKP---YKCEECGKS 728 Query: 634 FRSPSKLERHYLIHAGQKPFECSVCGKTFRQAPHWKRHQLTHFKERP 680 F S L H +IH G+KP++C G+ F + + H+ H E+P Sbjct: 729 FNQFSSLNIHKIIHTGEKPYKCGDYGRAFNLSSNLTTHKKIHTGEKP 775 Score = 200 bits (509), Expect = 3e-51 Identities = 175/710 (24%), Positives = 277/710 (39%), Gaps = 124/710 (17%) Query: 12 IQQCVVANKLPRNRPYVCNICFKHFETPSKLARHYLIHTGQKPFECDVCHKTFRQLVHLE 71 + QC+ A ++ + CN K F+ S R+ HTG K F+C C K+F L L Sbjct: 64 VNQCLTATP---SKIFQCNKYVKVFDKFSNSNRYKRRHTGNKHFKCKECSKSFCVLSQLT 120 Query: 72 RHQLTHSL--PFKCSICQRHFKNLKTFVKHQQLHNETYQNNVKQVRRLLEAKQEKSMYGV 129 +H+ H+ +KC C + F T KH+++H Sbjct: 121 QHRRIHTRVNSYKCEECGKAFNWFSTLTKHKRIH-------------------------- 154 Query: 130 YNTFTTEERWALHPCSKSDPMYS-MKRRKNIHA------CTICGKMFPSQSKLDRHVLIH 182 T E+ + C K+ S + R K IH C CGK F S L H +IH Sbjct: 155 ----TGEKPYKCEECGKAFNQSSQLTRHKIIHTEEKPNKCEECGKAFKQASHLTIHKIIH 210 Query: 183 TGQRPFKCVLCTKSFRQSTHLKIHQLTHSEERPFQCCFCQKGFKIQSKLLKHKQIHTRNK 242 TG++P+K C K F QS+HL ++ H+ E ++C C K F + S L HK+IH K Sbjct: 211 TGEKPYKYEECGKVFSQSSHLTTQKILHTGENLYKCKECGKAFNLFSNLTNHKRIHAGEK 270 Query: 243 AFRALLLKKRRTESRPLPNKLNANQGGFENGEIGESEENNPLDVHSIYIV---------- 292 ++ K + + + LN + G++ + EE + S+ + Sbjct: 271 PYKC----KECGRAFNISSNLNKQEKIHTGGKLNKCEECDKAFNRSLKLTAHKKILMEEK 326 Query: 293 PFQCPKCEKCFESEQILNEHSCFAARSGKIPSRFKRSYNYKTIVKKILAKLKRARSKKLD 352 P++C +C K F L H KI ++ Y K K KK+ Sbjct: 327 PYKCEECGKVFNQFSTLTRH--------KIIHTGEKPYKCKECGKAFNQSSNLTEHKKIH 378 Query: 353 NFQSEKKVFK--KSFLRNCDLISGEQSSEQTQRTFVGSLGKHGTYKTIGNRKKKTLTLPF 410 + K + K+F ++ +LI+ +RK + P+ Sbjct: 379 TAEKSYKCEECGKAFNQHSNLIN--------------------------HRKIYSGEKPY 412 Query: 411 SWQNMGKNLKGILTTENILSIDNSVNKKDLSICGSSGEEFFNNCEVLQCGFSVPRENIRT 470 + GK T I C + + N E + I T Sbjct: 413 KCEECGKAFNRSSTLTRHKKIHTGEKPYKCEECDRAFSQSSNLTE---------HKKIHT 463 Query: 471 RHKICPCDKCEKVFPSISKLKRHYLIHTGQRPFGCNICGKSFRQSAHLKRHEQTHNEKSP 530 K C++C K F S L +H IHTG++P+ C CGK+F QS L RH+ H ++ Sbjct: 464 GEKPYKCEECGKAFNRFSTLTKHKRIHTGEKPYKCEECGKAFNQSYQLTRHKIVHTKEK- 522 Query: 531 YASLCQVEFGNFNNLSNHSGNNVNYNASQQCQAPGVQKYEVSESDQMSGVKAESQDFIPG 590 + C+ EFG S+H + G + Y+ E ++ + Sbjct: 523 -LNKCE-EFGKAFKQSSH-------RTIHKIIHTGEKPYKCEEHGKVFNQSSNLTTQKII 573 Query: 591 STGQPCLPNVLLESEQSNPFCSYSEHQEKNDVFL----YRCSVCAKSFRSPSKLERHYLI 646 TG+ N+ E F +S ++ ++C C K++ S L H I Sbjct: 574 HTGE----NLYKFEEHGKAFNLFSNITNHKIIYTGEKPHKCEECGKAYNRFSNLTIHKRI 629 Query: 647 HAGQKPFECSVCGKTFRQAPHWKRHQLTHFKERPQ-----GKVVALDSVM 691 H G+KP++C+ CGK F + RH++ H E+P GK L S + Sbjct: 630 HTGEKPYQCAECGKAFNCSSTLNRHKIIHTGEKPYKCKECGKAFNLSSTL 679 Score = 197 bits (501), Expect = 3e-50 Identities = 176/696 (25%), Positives = 286/696 (41%), Gaps = 129/696 (18%) Query: 25 RPYVCNICFKHFETPSKLARHYLIHTGQKPFECDVCHKTFRQLVHLERHQLTHS--LPFK 82 +PY C C K F S+L RH +IHT +KP +C+ C K F+Q HL H++ H+ P+K Sbjct: 158 KPYKCEECGKAFNQSSQLTRHKIIHTEEKPNKCEECGKAFKQASHLTIHKIIHTGEKPYK 217 Query: 83 CSICQRHFKNLKTFVKHQQLH-------------------NETYQNNVKQVRRLLEAKQE 123 C + F + LH N T + + + K+ Sbjct: 218 YEECGKVFSQSSHLTTQKILHTGENLYKCKECGKAFNLFSNLTNHKRIHAGEKPYKCKEC 277 Query: 124 KSMYGVYNTFTTEER----WALHPCSKSDPMYSMKRRKNIHA----------CTICGKMF 169 + + + +E+ L+ C + D ++ + H C CGK+F Sbjct: 278 GRAFNISSNLNKQEKIHTGGKLNKCEECDKAFNRSLKLTAHKKILMEEKPYKCEECGKVF 337 Query: 170 PSQSKLDRHVLIHTGQRPFKCVLCTKSFRQSTHLKIHQLTHSEERPFQCCFCQKGFKIQS 229 S L RH +IHTG++P+KC C K+F QS++L H+ H+ E+ ++C C K F S Sbjct: 338 NQFSTLTRHKIIHTGEKPYKCKECGKAFNQSSNLTEHKKIHTAEKSYKCEECGKAFNQHS 397 Query: 230 KLLKHKQIHTRNKAFRALLLKKRRTESRPLPN--KLNANQGGFENGEIGE--SEENNPLD 285 L+ H++I++ K ++ K S L K++ + ++ E S+ +N + Sbjct: 398 NLINHRKIYSGEKPYKCEECGKAFNRSSTLTRHKKIHTGEKPYKCEECDRAFSQSSNLTE 457 Query: 286 VHSIYI--VPFQCPKCEKCFESEQILNEHSCFAARSGKIPSR-------FKRSYNYKTIV 336 I+ P++C +C K F L +H +G+ P + F +SY Sbjct: 458 HKKIHTGEKPYKCEECGKAFNRFSTLTKHK--RIHTGEKPYKCEECGKAFNQSYQ----- 510 Query: 337 KKILAKLKRARSK-KLDNFQSEKKVFKKSFLRNCDLI--SGEQSSEQTQRTFVGSLGKHG 393 L + K +K KL+ + K FK+S R I +GE+ + + V + + Sbjct: 511 ---LTRHKIVHTKEKLNKCEEFGKAFKQSSHRTIHKIIHTGEKPYKCEEHGKVFNQSSNL 567 Query: 394 TYKTIGNRKKKTLTLPFSWQNMGK--NLKGILTTENILSIDNSVNKKDLSICGSSGEEFF 451 T + I + + + ++ GK NL +T I+ +K + CG + F Sbjct: 568 TTQKIIHTGENL----YKFEEHGKAFNLFSNITNHKIIYTGEKPHKCEE--CGKAYNRFS 621 Query: 452 NNCEVLQCGFSVPRENIRTRHKICPCDKCEKVFPSISKLKRHYLIHTGQRPFGCNICGKS 511 N + I T K C +C K F S L RH +IHTG++P+ C CGK+ Sbjct: 622 N---------LTIHKRIHTGEKPYQCAECGKAFNCSSTLNRHKIIHTGEKPYKCKECGKA 672 Query: 512 FRQSAHLKRHEQTHNEKSPY-ASLCQVEFGNFNNLSNHSGNNVNYNASQQCQAPGVQKYE 570 F S+ L H++ H + PY C F +NL+ H +K Sbjct: 673 FNLSSTLTAHKKIHTGEKPYKCEECGKAFNQSSNLTTH------------------KKIH 714 Query: 571 VSESDQMSGVKAESQDFIPGSTGQPCLPNVLLESEQSNPFCSYSEHQ-----EKNDVFLY 625 SE + C + N F S + H+ EK Y Sbjct: 715 TSEKPYKC---------------EEC-------GKSFNQFSSLNIHKIIHTGEKP----Y 748 Query: 626 RCSVCAKSFRSPSKLERHYLIHAGQKPFECSVCGKT 661 +C ++F S L H IH G+KP++C GKT Sbjct: 749 KCGDYGRAFNLSSNLTTHKKIHTGEKPYKCEY-GKT 783 >gi|7706775 zinc finger protein 107 [Homo sapiens] Length = 783 Score = 202 bits (515), Expect = 6e-52 Identities = 186/707 (26%), Positives = 297/707 (42%), Gaps = 108/707 (15%) Query: 23 RNRPYVCNICFKHFETPSKLARHYLIHTGQKPFECDVCHKTFRQLVHLERHQLTHS--LP 80 R Y C C K F S L +H IHTG+KP++C+ C K F Q L RH++ H+ P Sbjct: 128 RVNSYKCEECGKAFNWFSTLTKHKRIHTGEKPYKCEECGKAFNQSSQLTRHKIIHTEEKP 187 Query: 81 FKCSICQRHFKNLKTFVKHQQLHNETYQNNVKQVRRLLEAKQEKSMYGVYNTFTTEERWA 140 KC C + FK H+ +H ++ ++ + + +T E + Sbjct: 188 NKCEECGKAFKQASHLTIHKIIHTGEKPYKYEECGKVFSQSSHLTTQKILHT--GENLYK 245 Query: 141 LHPCSKSDPMYS-MKRRKNIHA------CTICGKMFPSQSKLDRHVLIHTGQRPFKCVLC 193 C K+ ++S + K IHA C CG+ F S L++ IHTG + KC C Sbjct: 246 CKECGKAFNLFSNLTNHKRIHAGEKPYKCKECGRAFNISSNLNKQEKIHTGGKLNKCEEC 305 Query: 194 TKSFRQSTHLKIHQLTHSEERPFQCCFCQKGFKIQSKLLKHKQIHTRNKAFRALLLKKRR 253 K+F +S L H+ EE+P++C C K F S L +HK IHT K ++ K Sbjct: 306 DKAFNRSLKLTAHKKILMEEKPYKCEECGKVFNQFSTLTRHKIIHTGEKPYKCKECGKAF 365 Query: 254 TESRPLPN--KLNANQGGFENGEIGES--EENNPLDVHSIYI--VPFQCPKCEKCFESEQ 307 +S L K++ + ++ E G++ + +N ++ IY P++C +C K F Sbjct: 366 NQSSNLTEHKKIHTAEKSYKCEECGKAFNQHSNLINHRKIYSGEKPYKCEECGKAFNRSS 425 Query: 308 ILNEHSCFAARSGKIPSR-------FKRSYNYKTIVKKI--------------------- 339 L H +G+ P + F +S N T KKI Sbjct: 426 TLTRHK--KIHTGEKPYKCEECDRAFSQSSNL-TEHKKIHTGEKPYKCEECGKAFNRFST 482 Query: 340 LAKLKRARS-KKLDNFQSEKKVFKKSF-LRNCDLISGEQSSEQTQRTFVGSLGKHGTYKT 397 L K KR + +K + K F +S+ L ++ ++ + + G K +++T Sbjct: 483 LTKHKRIHTGEKPYKCEECGKAFNQSYQLTRHKIVHTKEKLNKCEE--FGKAFKQSSHRT 540 Query: 398 IGNRKKKTLTLPFSWQNMGK--NLKGILTTENILSIDNSVNKKDLSICGSSGEEF--FNN 453 I ++ T P+ + GK N LTT+ I+ ++ K + G+ F F+N Sbjct: 541 I-HKIIHTGEKPYKCEEHGKVFNQSSNLTTQKIIHTGENLYKFE-----EHGKAFNLFSN 594 Query: 454 CEVLQCGFSVPRENIRTRHKICPCDKCEKVFPSISKLKRHYLIHTGQRPFGCNICGKSFR 513 + I T K C++C K + S L H IHTG++P+ C CGK+F Sbjct: 595 I--------TNHKIIYTGEKPHKCEECGKAYNRFSNLTIHKRIHTGEKPYQCAECGKAFN 646 Query: 514 QSAHLKRHEQTHNEKSPYASLCQVEFGNFNNLSNHSGNNVNYNASQQCQAPGVQKYEVSE 573 S+ L RH+ H + PY C+ E G NLS+ A ++ G + Y+ E Sbjct: 647 CSSTLNRHKIIHTGEKPYK--CK-ECGKAFNLSS------TLTAHKKIHT-GEKPYKCEE 696 Query: 574 SDQMSGVKAESQDFIPGSTGQPCLPNVLLESEQSNPFCSYSEHQEKNDVFLYRCSVCAKS 633 + ++ SN H + Y+C C KS Sbjct: 697 CGKAF-------------------------NQSSNLTTHKKIHTSEKP---YKCEECGKS 728 Query: 634 FRSPSKLERHYLIHAGQKPFECSVCGKTFRQAPHWKRHQLTHFKERP 680 F S L H +IH G+KP++C G+ F + + H+ H E+P Sbjct: 729 FNQFSSLNIHKIIHTGEKPYKCGDYGRAFNLSSNLTTHKKIHTGEKP 775 Score = 200 bits (509), Expect = 3e-51 Identities = 175/710 (24%), Positives = 277/710 (39%), Gaps = 124/710 (17%) Query: 12 IQQCVVANKLPRNRPYVCNICFKHFETPSKLARHYLIHTGQKPFECDVCHKTFRQLVHLE 71 + QC+ A ++ + CN K F+ S R+ HTG K F+C C K+F L L Sbjct: 64 VNQCLTATP---SKIFQCNKYVKVFDKFSNSNRYKRRHTGNKHFKCKECSKSFCVLSQLT 120 Query: 72 RHQLTHSL--PFKCSICQRHFKNLKTFVKHQQLHNETYQNNVKQVRRLLEAKQEKSMYGV 129 +H+ H+ +KC C + F T KH+++H Sbjct: 121 QHRRIHTRVNSYKCEECGKAFNWFSTLTKHKRIH-------------------------- 154 Query: 130 YNTFTTEERWALHPCSKSDPMYS-MKRRKNIHA------CTICGKMFPSQSKLDRHVLIH 182 T E+ + C K+ S + R K IH C CGK F S L H +IH Sbjct: 155 ----TGEKPYKCEECGKAFNQSSQLTRHKIIHTEEKPNKCEECGKAFKQASHLTIHKIIH 210 Query: 183 TGQRPFKCVLCTKSFRQSTHLKIHQLTHSEERPFQCCFCQKGFKIQSKLLKHKQIHTRNK 242 TG++P+K C K F QS+HL ++ H+ E ++C C K F + S L HK+IH K Sbjct: 211 TGEKPYKYEECGKVFSQSSHLTTQKILHTGENLYKCKECGKAFNLFSNLTNHKRIHAGEK 270 Query: 243 AFRALLLKKRRTESRPLPNKLNANQGGFENGEIGESEENNPLDVHSIYIV---------- 292 ++ K + + + LN + G++ + EE + S+ + Sbjct: 271 PYKC----KECGRAFNISSNLNKQEKIHTGGKLNKCEECDKAFNRSLKLTAHKKILMEEK 326 Query: 293 PFQCPKCEKCFESEQILNEHSCFAARSGKIPSRFKRSYNYKTIVKKILAKLKRARSKKLD 352 P++C +C K F L H KI ++ Y K K KK+ Sbjct: 327 PYKCEECGKVFNQFSTLTRH--------KIIHTGEKPYKCKECGKAFNQSSNLTEHKKIH 378 Query: 353 NFQSEKKVFK--KSFLRNCDLISGEQSSEQTQRTFVGSLGKHGTYKTIGNRKKKTLTLPF 410 + K + K+F ++ +LI+ +RK + P+ Sbjct: 379 TAEKSYKCEECGKAFNQHSNLIN--------------------------HRKIYSGEKPY 412 Query: 411 SWQNMGKNLKGILTTENILSIDNSVNKKDLSICGSSGEEFFNNCEVLQCGFSVPRENIRT 470 + GK T I C + + N E + I T Sbjct: 413 KCEECGKAFNRSSTLTRHKKIHTGEKPYKCEECDRAFSQSSNLTE---------HKKIHT 463 Query: 471 RHKICPCDKCEKVFPSISKLKRHYLIHTGQRPFGCNICGKSFRQSAHLKRHEQTHNEKSP 530 K C++C K F S L +H IHTG++P+ C CGK+F QS L RH+ H ++ Sbjct: 464 GEKPYKCEECGKAFNRFSTLTKHKRIHTGEKPYKCEECGKAFNQSYQLTRHKIVHTKEK- 522 Query: 531 YASLCQVEFGNFNNLSNHSGNNVNYNASQQCQAPGVQKYEVSESDQMSGVKAESQDFIPG 590 + C+ EFG S+H + G + Y+ E ++ + Sbjct: 523 -LNKCE-EFGKAFKQSSH-------RTIHKIIHTGEKPYKCEEHGKVFNQSSNLTTQKII 573 Query: 591 STGQPCLPNVLLESEQSNPFCSYSEHQEKNDVFL----YRCSVCAKSFRSPSKLERHYLI 646 TG+ N+ E F +S ++ ++C C K++ S L H I Sbjct: 574 HTGE----NLYKFEEHGKAFNLFSNITNHKIIYTGEKPHKCEECGKAYNRFSNLTIHKRI 629 Query: 647 HAGQKPFECSVCGKTFRQAPHWKRHQLTHFKERPQ-----GKVVALDSVM 691 H G+KP++C+ CGK F + RH++ H E+P GK L S + Sbjct: 630 HTGEKPYQCAECGKAFNCSSTLNRHKIIHTGEKPYKCKECGKAFNLSSTL 679 Score = 197 bits (501), Expect = 3e-50 Identities = 176/696 (25%), Positives = 286/696 (41%), Gaps = 129/696 (18%) Query: 25 RPYVCNICFKHFETPSKLARHYLIHTGQKPFECDVCHKTFRQLVHLERHQLTHS--LPFK 82 +PY C C K F S+L RH +IHT +KP +C+ C K F+Q HL H++ H+ P+K Sbjct: 158 KPYKCEECGKAFNQSSQLTRHKIIHTEEKPNKCEECGKAFKQASHLTIHKIIHTGEKPYK 217 Query: 83 CSICQRHFKNLKTFVKHQQLH-------------------NETYQNNVKQVRRLLEAKQE 123 C + F + LH N T + + + K+ Sbjct: 218 YEECGKVFSQSSHLTTQKILHTGENLYKCKECGKAFNLFSNLTNHKRIHAGEKPYKCKEC 277 Query: 124 KSMYGVYNTFTTEER----WALHPCSKSDPMYSMKRRKNIHA----------CTICGKMF 169 + + + +E+ L+ C + D ++ + H C CGK+F Sbjct: 278 GRAFNISSNLNKQEKIHTGGKLNKCEECDKAFNRSLKLTAHKKILMEEKPYKCEECGKVF 337 Query: 170 PSQSKLDRHVLIHTGQRPFKCVLCTKSFRQSTHLKIHQLTHSEERPFQCCFCQKGFKIQS 229 S L RH +IHTG++P+KC C K+F QS++L H+ H+ E+ ++C C K F S Sbjct: 338 NQFSTLTRHKIIHTGEKPYKCKECGKAFNQSSNLTEHKKIHTAEKSYKCEECGKAFNQHS 397 Query: 230 KLLKHKQIHTRNKAFRALLLKKRRTESRPLPN--KLNANQGGFENGEIGE--SEENNPLD 285 L+ H++I++ K ++ K S L K++ + ++ E S+ +N + Sbjct: 398 NLINHRKIYSGEKPYKCEECGKAFNRSSTLTRHKKIHTGEKPYKCEECDRAFSQSSNLTE 457 Query: 286 VHSIYI--VPFQCPKCEKCFESEQILNEHSCFAARSGKIPSR-------FKRSYNYKTIV 336 I+ P++C +C K F L +H +G+ P + F +SY Sbjct: 458 HKKIHTGEKPYKCEECGKAFNRFSTLTKHK--RIHTGEKPYKCEECGKAFNQSYQ----- 510 Query: 337 KKILAKLKRARSK-KLDNFQSEKKVFKKSFLRNCDLI--SGEQSSEQTQRTFVGSLGKHG 393 L + K +K KL+ + K FK+S R I +GE+ + + V + + Sbjct: 511 ---LTRHKIVHTKEKLNKCEEFGKAFKQSSHRTIHKIIHTGEKPYKCEEHGKVFNQSSNL 567 Query: 394 TYKTIGNRKKKTLTLPFSWQNMGK--NLKGILTTENILSIDNSVNKKDLSICGSSGEEFF 451 T + I + + + ++ GK NL +T I+ +K + CG + F Sbjct: 568 TTQKIIHTGENL----YKFEEHGKAFNLFSNITNHKIIYTGEKPHKCEE--CGKAYNRFS 621 Query: 452 NNCEVLQCGFSVPRENIRTRHKICPCDKCEKVFPSISKLKRHYLIHTGQRPFGCNICGKS 511 N + I T K C +C K F S L RH +IHTG++P+ C CGK+ Sbjct: 622 N---------LTIHKRIHTGEKPYQCAECGKAFNCSSTLNRHKIIHTGEKPYKCKECGKA 672 Query: 512 FRQSAHLKRHEQTHNEKSPY-ASLCQVEFGNFNNLSNHSGNNVNYNASQQCQAPGVQKYE 570 F S+ L H++ H + PY C F +NL+ H +K Sbjct: 673 FNLSSTLTAHKKIHTGEKPYKCEECGKAFNQSSNLTTH------------------KKIH 714 Query: 571 VSESDQMSGVKAESQDFIPGSTGQPCLPNVLLESEQSNPFCSYSEHQ-----EKNDVFLY 625 SE + C + N F S + H+ EK Y Sbjct: 715 TSEKPYKC---------------EEC-------GKSFNQFSSLNIHKIIHTGEKP----Y 748 Query: 626 RCSVCAKSFRSPSKLERHYLIHAGQKPFECSVCGKT 661 +C ++F S L H IH G+KP++C GKT Sbjct: 749 KCGDYGRAFNLSSNLTTHKKIHTGEKPYKCEY-GKT 783 >gi|11386193 zinc finger protein 197 isoform 1 [Homo sapiens] Length = 1029 Score = 202 bits (515), Expect = 6e-52 Identities = 175/679 (25%), Positives = 271/679 (39%), Gaps = 88/679 (12%) Query: 27 YVCNICFKHFETPSKLARHYLIHTGQKPFECDVCHKTFRQLVHLERHQLTHS--LPFKCS 84 Y C++C KHF S L H IHTG+KP +C C K F Q L H HS P+KC+ Sbjct: 370 YKCDMCCKHFNKISHLINHRRIHTGEKPHKCKECGKGFIQRSSLLMHLRNHSGEKPYKCN 429 Query: 85 ICQRHFKNLKTFVKHQQLHNETYQNNVKQVRRLLEAKQEKSMYGVYNTFTTEERWALHPC 144 C + F + HQ++H K+ + + + + E + + C Sbjct: 430 ECGKAFSQSAYLLNHQRIHTGEKPYKCKECGK--GFYRHSGLIIHLRRHSGERPYKCNEC 487 Query: 145 SK--SDPMY-----SMKRRKNIHACTICGKMFPSQSKLDRHVLIHTGQRPFKCVLCTKSF 197 K S Y + + + + C C K F + L H IH+G++P+KC C K+F Sbjct: 488 GKVFSQNAYLIDHQRLHKGEEPYKCNKCQKAFILKKSLILHQRIHSGEKPYKCDECGKTF 547 Query: 198 RQSTHLKIHQLTHSEERPFQCCFCQKGFKIQSKLLKHKQIHTRNKAF-----------RA 246 Q+T+L HQ HS E P++C C K F LL H+++HT K F ++ Sbjct: 548 AQTTYLIDHQRLHSAENPYKCKECGKVFIRSKSLLLHQRVHTEKKTFGCKKCGKIFSSKS 607 Query: 247 LLLKKRRTESRPLPNKLNANQGGFENGEIGESEENNPLDVHSIYIVPFQCPKCEKCFESE 306 + +R SR P K F + +H+ P++C +C K F + Sbjct: 608 NFIDHKRMHSREKPYKCTECGKAFTQSAYLFDHQR----LHN-GEKPYECNECGKVFILK 662 Query: 307 QILNEHSCFAARSGKIPSRFKRSYNYKTIVKKILAKLKRARSKKLDNFQS--EKKVFKKS 364 + L H F + Y K K + ++L N + E + K+ Sbjct: 663 KSLILHQRFHTG--------ENLYECKDCGKVFGSNRNLIDHERLHNGEKPYECRECGKT 714 Query: 365 FLRNCDLISGEQSSEQTQRTFVGSLGKHGTYKT--IGNRKKKTLTLPFSWQNMGKNLKGI 422 F+ + + ++ Q + GK +Y + + +R+ T PF G+ Sbjct: 715 FIMSKSFMVHQKLHTQEKAYKCEDCGKAFSYNSSLLVHRRIHTGEKPFECSECGRAFSSN 774 Query: 423 LTTENILSIDNSVNKKDLSICGSSGEEFFNNCEVLQCGFSVPRENIRTRHKICPCDKCEK 482 I + + CG C +L+ + + I TR K C+ C K Sbjct: 775 RNLIEHKRIHSGEKPYECDECG--------KCFILKKSL-IGHQRIHTREKSYKCNDCGK 825 Query: 483 VFPSISKLKRHYLIHTGQRPFGCNICGKSFRQSAHLKRHEQTHN-EKSPYASLCQVEFGN 541 VF S L H IHTG++P+ C+ CGK F + +L H++ H+ EK+ +C+ + Sbjct: 826 VFSYRSNLIAHQRIHTGEKPYACSECGKGFTYNRNLIEHQRIHSGEKTYECHVCRKVLTS 885 Query: 542 FNNLSNHSGNNVNYNASQQCQAPGVQKYEVSESDQMSGVKAESQDFIPGSTGQPCLPNVL 601 NL H Q G + Y+ +E +DF Sbjct: 886 SRNLMVH-----------QRIHTGEKPYKCNEC---------GKDF-------------- 911 Query: 602 LESEQSNPFCSYSEHQEKNDVFLYRCSVCAKSFRSPSKLERHYLIHAGQKPFECSVCGKT 661 S+ N H + Y C C KSF S L H IH G+KP+ C+ C K Sbjct: 912 --SQNKNLVVHQRMHTGEKP---YECDKCRKSFTSKRNLVGHQRIHTGEKPYGCNDCSKV 966 Query: 662 FRQAPHWKRHQLTHFKERP 680 FRQ + HQ H E+P Sbjct: 967 FRQRKNLTVHQKIHTDEKP 985 Score = 192 bits (489), Expect = 7e-49 Identities = 146/562 (25%), Positives = 230/562 (40%), Gaps = 110/562 (19%) Query: 26 PYVCNICFKHFETPSKLARHYLIHTGQKPFECDVCHKTFRQLVHLERHQLTHSL--PFKC 83 PY CN C K F L H IH+G+KP++CD C KTF Q +L HQ HS P+KC Sbjct: 509 PYKCNKCQKAFILKKSLILHQRIHSGEKPYKCDECGKTFAQTTYLIDHQRLHSAENPYKC 568 Query: 84 SICQRHFKNLKTFVKHQQLHNETYQNNVKQVRRLLEAKQE----KSMYGVYNTFTTEE-- 137 C + F K+ + HQ++H E K+ ++ +K K M+ + E Sbjct: 569 KECGKVFIRSKSLLLHQRVHTEKKTFGCKKCGKIFSSKSNFIDHKRMHSREKPYKCTECG 628 Query: 138 -----------RWALH------PCSKSDPMYSMKRR----------KNIHACTICGKMFP 170 LH C++ ++ +K+ +N++ C CGK+F Sbjct: 629 KAFTQSAYLFDHQRLHNGEKPYECNECGKVFILKKSLILHQRFHTGENLYECKDCGKVFG 688 Query: 171 SQSKLDRHVLIHTGQRPFKCVLCTKSFRQSTHLKIHQLTHSEERPFQCCFCQKGFKIQSK 230 S L H +H G++P++C C K+F S +HQ H++E+ ++C C K F S Sbjct: 689 SNRNLIDHERLHNGEKPYECRECGKTFIMSKSFMVHQKLHTQEKAYKCEDCGKAFSYNSS 748 Query: 231 LLKHKQIHTRNKAFRALLLKKRRTESRPLPNKLNANQGGFENGEIGESEENNPLDVHSIY 290 LL H++IHT K F E ++N+ E+ I E+ Sbjct: 749 LLVHRRIHTGEKPF----------ECSECGRAFSSNRNLIEHKRIHSGEK---------- 788 Query: 291 IVPFQCPKCEKCFESEQILNEHSCFAARSGKIPSRFKRSYNYKTIVKKILAKLKRARSKK 350 P++C +C KCF ++ L H R ++SY K + ++ Sbjct: 789 --PYECDECGKCFILKKSLIGHQRIHTR--------EKSYKCNDCGKVFSYRSNLIAHQR 838 Query: 351 LDNFQSEKKVFK--KSFLRNCDLISGEQ--SSEQTQRTFVGSLGKHGTYKTIGNRKKKTL 406 + + + K F N +LI ++ S E+T V Sbjct: 839 IHTGEKPYACSECGKGFTYNRNLIEHQRIHSGEKTYECHV-------------------- 878 Query: 407 TLPFSWQNMGKNLKGILTTENILSIDNSVNKKDLSI-CGSSGEEFFNNCEVLQCGFSVPR 465 + +LT+ L + ++ + C G++F N + V Sbjct: 879 ------------CRKVLTSSRNLMVHQRIHTGEKPYKCNECGKDFSQNKNL------VVH 920 Query: 466 ENIRTRHKICPCDKCEKVFPSISKLKRHYLIHTGQRPFGCNICGKSFRQSAHLKRHEQTH 525 + + T K CDKC K F S L H IHTG++P+GCN C K FRQ +L H++ H Sbjct: 921 QRMHTGEKPYECDKCRKSFTSKRNLVGHQRIHTGEKPYGCNDCSKVFRQRKNLTVHQKIH 980 Query: 526 NEKSPYASLCQVEFGNFNNLSN 547 ++ P C V F+ SN Sbjct: 981 TDEKPCE--CDVSEKEFSQTSN 1000 Score = 186 bits (472), Expect = 6e-47 Identities = 166/662 (25%), Positives = 264/662 (39%), Gaps = 88/662 (13%) Query: 25 RPYVCNICFKHFETPSKLARHYLIHTGQKPFECDVCHKTFRQ----LVHLERHQLTHSLP 80 +PY CN C K F + L H IHTG+KP++C C K F + ++HL RH + P Sbjct: 424 KPYKCNECGKAFSQSAYLLNHQRIHTGEKPYKCKECGKGFYRHSGLIIHLRRH--SGERP 481 Query: 81 FKCSICQRHFKNLKTFVKHQQLHN--ETYQNNVKQVRRLLEAKQEKSMYGVYNTFTTEER 138 +KC+ C + F + HQ+LH E Y+ N Q F ++ Sbjct: 482 YKCNECGKVFSQNAYLIDHQRLHKGEEPYKCNKCQ-----------------KAFILKKS 524 Query: 139 WALHPCSKSDPMYSMKRRKNIHACTICGKMFPSQSKLDRHVLIHTGQRPFKCVLCTKSFR 198 LH S + + C CGK F + L H +H+ + P+KC C K F Sbjct: 525 LILHQRIHSG--------EKPYKCDECGKTFAQTTYLIDHQRLHSAENPYKCKECGKVFI 576 Query: 199 QSTHLKIHQLTHSEERPFQCCFCQKGFKIQSKLLKHKQIHTRNKAFRALLLKKRRTESRP 258 +S L +HQ H+E++ F C C K F +S + HK++H+R K ++ K T+S Sbjct: 577 RSKSLLLHQRVHTEKKTFGCKKCGKIFSSKSNFIDHKRMHSREKPYKCTECGKAFTQSAY 636 Query: 259 LPNKLNANQGGFENGEIGESEENNPLDVHSIYIVPFQCPKCEKCFESEQILNEHSCFAAR 318 L F++ + E+ P++C +C K F ++ L H F Sbjct: 637 L----------FDHQRLHNGEK------------PYECNECGKVFILKKSLILHQRFHTG 674 Query: 319 SGKIPSRFKRSYNYKTIVKKILAKLKRARSKKLDNFQS--EKKVFKKSFLRNCDLISGEQ 376 + Y K K + ++L N + E + K+F+ + + ++ Sbjct: 675 --------ENLYECKDCGKVFGSNRNLIDHERLHNGEKPYECRECGKTFIMSKSFMVHQK 726 Query: 377 SSEQTQRTFVGSLGKHGTYKT--IGNRKKKTLTLPFSWQNMGKNLKGILTTENILSIDNS 434 Q + GK +Y + + +R+ T PF G+ I + Sbjct: 727 LHTQEKAYKCEDCGKAFSYNSSLLVHRRIHTGEKPFECSECGRAFSSNRNLIEHKRIHSG 786 Query: 435 VNKKDLSICGSSGEEFFNNCEVLQCGFSVPRENIRTRHKICPCDKCEKVFPSISKLKRHY 494 + CG C +L+ + + I TR K C+ C KVF S L H Sbjct: 787 EKPYECDECGK--------CFILKKSL-IGHQRIHTREKSYKCNDCGKVFSYRSNLIAHQ 837 Query: 495 LIHTGQRPFGCNICGKSFRQSAHLKRHEQTHN-EKSPYASLCQVEFGNFNNLSNHSGNNV 553 IHTG++P+ C+ CGK F + +L H++ H+ EK+ +C+ + NL H + Sbjct: 838 RIHTGEKPYACSECGKGFTYNRNLIEHQRIHSGEKTYECHVCRKVLTSSRNLMVHQRIHT 897 Query: 554 NYNASQQCQAPGVQKYEVSESDQMSGVKAESQDFIPGSTGQPCLPNVLLESEQSNPFCSY 613 +C G + S++ + Q G C + + N Sbjct: 898 G-EKPYKCNECGK---DFSQNKNL----VVHQRMHTGEKPYECDKCRKSFTSKRNLVGHQ 949 Query: 614 SEHQEKNDVFLYRCSVCAKSFRSPSKLERHYLIHAGQKPFECSVCGKTFRQAPHWKRHQL 673 H + Y C+ C+K FR L H IH +KP EC V K F Q + Q Sbjct: 950 RIHTGEKP---YGCNDCSKVFRQRKNLTVHQKIHTDEKPCECDVSEKEFSQTSNLHLQQK 1006 Query: 674 TH 675 H Sbjct: 1007 IH 1008 Score = 143 bits (361), Expect = 5e-34 Identities = 147/584 (25%), Positives = 229/584 (39%), Gaps = 81/584 (13%) Query: 157 KNIHACTICGKMFPSQSKLDRHVLIHTGQRPFKCVLCTKSFRQSTHLKIHQLTHSEERPF 216 K + C +C K F S L H IHTG++P KC C K F Q + L +H HS E+P+ Sbjct: 367 KKFYKCDMCCKHFNKISHLINHRRIHTGEKPHKCKECGKGFIQRSSLLMHLRNHSGEKPY 426 Query: 217 QCCFCQKGFKIQSKLLKHKQIHTRNKAFRAL-----------LLKKRRTESRPLPNKLN- 264 +C C K F + LL H++IHT K ++ L+ R S P K N Sbjct: 427 KCNECGKAFSQSAYLLNHQRIHTGEKPYKCKECGKGFYRHSGLIIHLRRHSGERPYKCNE 486 Query: 265 ------ANQGGFENGEIGESEENNPLD-VHSIYIV---------------PFQCPKCEKC 302 N ++ + + EE + +I+ P++C +C K Sbjct: 487 CGKVFSQNAYLIDHQRLHKGEEPYKCNKCQKAFILKKSLILHQRIHSGEKPYKCDECGKT 546 Query: 303 FESEQILNEHSCFAARSGKIPSRFKRSYNYKTIVKKILAKLKRARSKKLDNFQSEKKVF- 361 F L +H S + P + K K +L + KK + K+F Sbjct: 547 FAQTTYLIDHQ--RLHSAENPYKCKECGKVFIRSKSLLLHQRVHTEKKTFGCKKCGKIFS 604 Query: 362 -KKSFLRNCDLISGEQSSEQTQ--RTFVGSLGKHGTYKTIGNRK-------------KKT 405 K +F+ + + S E+ + T+ + F S + K KK+ Sbjct: 605 SKSNFIDHKRMHSREKPYKCTECGKAFTQSAYLFDHQRLHNGEKPYECNECGKVFILKKS 664 Query: 406 LTLPFSWQNMGKNL-------KGILTTENILSIDNSVNKKDLSICGSSGEEFFNNCEVLQ 458 L L + + G+NL K + N++ + N + C G+ F ++ Sbjct: 665 LILHQRF-HTGENLYECKDCGKVFGSNRNLIDHERLHNGEKPYECRECGKTF-----IMS 718 Query: 459 CGFSVPRENIRTRHKICPCDKCEKVFPSISKLKRHYLIHTGQRPFGCNICGKSFRQSAHL 518 F V + + T+ K C+ C K F S L H IHTG++PF C+ CG++F + +L Sbjct: 719 KSFMV-HQKLHTQEKAYKCEDCGKAFSYNSSLLVHRRIHTGEKPFECSECGRAFSSNRNL 777 Query: 519 KRHEQTHNEKSPY-ASLCQVEFGNFNNLSNHSGNNVNYNASQQCQAPGVQKYEVSESDQM 577 H++ H+ + PY C F +L H + S +C G S Sbjct: 778 IEHKRIHSGEKPYECDECGKCFILKKSLIGHQRIHTR-EKSYKCNDCGKVFSYRSNLIAH 836 Query: 578 SGVKAESQDFIPGSTGQPCLPNVLLESEQSNPFCSYSEHQE-KNDVFLYRCSVCAKSFRS 636 + + + G+ N L EHQ + Y C VC K S Sbjct: 837 QRIHTGEKPYACSECGKGFTYNRNL-----------IEHQRIHSGEKTYECHVCRKVLTS 885 Query: 637 PSKLERHYLIHAGQKPFECSVCGKTFRQAPHWKRHQLTHFKERP 680 L H IH G+KP++C+ CGK F Q + HQ H E+P Sbjct: 886 SRNLMVHQRIHTGEKPYKCNECGKDFSQNKNLVVHQRMHTGEKP 929 Score = 129 bits (323), Expect = 1e-29 Identities = 71/231 (30%), Positives = 113/231 (48%), Gaps = 11/231 (4%) Query: 23 RNRPYVCNICFKHFETPSKLARHYLIHTGQKPFECDVCHKTFRQLVHLERHQLTHS--LP 80 + + Y C C K F S L H IHTG+KPFEC C + F +L H+ HS P Sbjct: 730 QEKAYKCEDCGKAFSYNSSLLVHRRIHTGEKPFECSECGRAFSSNRNLIEHKRIHSGEKP 789 Query: 81 FKCSICQRHFKNLKTFVKHQQLHNETYQNNVKQVRRLLEAKQEKSMYGVYNTFTTEERWA 140 ++C C + F K+ + HQ++H ++ + ++ T E+ +A Sbjct: 790 YECDECGKCFILKKSLIGHQRIHTREKSYKCNDCGKVFSYRS--NLIAHQRIHTGEKPYA 847 Query: 141 LHPCSKSDPMY-SMKRRKNIHA------CTICGKMFPSQSKLDRHVLIHTGQRPFKCVLC 193 C K ++ + IH+ C +C K+ S L H IHTG++P+KC C Sbjct: 848 CSECGKGFTYNRNLIEHQRIHSGEKTYECHVCRKVLTSSRNLMVHQRIHTGEKPYKCNEC 907 Query: 194 TKSFRQSTHLKIHQLTHSEERPFQCCFCQKGFKIQSKLLKHKQIHTRNKAF 244 K F Q+ +L +HQ H+ E+P++C C+K F + L+ H++IHT K + Sbjct: 908 GKDFSQNKNLVVHQRMHTGEKPYECDKCRKSFTSKRNLVGHQRIHTGEKPY 958 Score = 125 bits (313), Expect = 2e-28 Identities = 121/518 (23%), Positives = 201/518 (38%), Gaps = 115/518 (22%) Query: 184 GQRPFKCVLCTKSFRQSTHLKIHQLTHSEERPFQCCFCQKGFKIQSKLLKHKQIHTRNKA 243 G++ +KC +C K F + +HL H+ H+ E+P +C C KGF +S LL H + H+ K Sbjct: 366 GKKFYKCDMCCKHFNKISHLINHRRIHTGEKPHKCKECGKGFIQRSSLLMHLRNHSGEKP 425 Query: 244 FRALLLKKRRTESRPLPN--KLNANQGGFENGEIGESEENNPLDVHSIYIV--------- 292 ++ K ++S L N +++ + ++ E G+ HS I+ Sbjct: 426 YKCNECGKAFSQSAYLLNHQRIHTGEKPYKCKECGKGFYR-----HSGLIIHLRRHSGER 480 Query: 293 PFQCPKCEKCFESEQILNEHSCFAARSGKIPSRFKRSYNYKTIVKKILAKLKRARSKKLD 352 P++C +C K F L +H +L + Sbjct: 481 PYKCNECGKVFSQNAYLIDHQ----------------------------RLHKGEEPYKC 512 Query: 353 NFQSEKKVFKKSFLRNCDLISGEQ--SSEQTQRTFVGSLGKHGTYKTIGNRKKKTLTLPF 410 N + + KKS + + + SGE+ ++ +TF + TY Sbjct: 513 NKCQKAFILKKSLILHQRIHSGEKPYKCDECGKTFAQT-----TY--------------- 552 Query: 411 SWQNMGKNLKGILTTENILSIDNSVNKKDLSICGSSGEEFFNNCEVLQCGFSVPRENIRT 470 ++ + + S +N C G+ F + +L + + T Sbjct: 553 -----------LIDHQRLHSAENPYK------CKECGKVFIRSKSLLL------HQRVHT 589 Query: 471 RHKICPCDKCEKVFPSISKLKRHYLIHTGQRPFGCNICGKSFRQSAHLKRHEQTHNEKSP 530 K C KC K+F S S H +H+ ++P+ C CGK+F QSA+L H++ HN + P Sbjct: 590 EKKTFGCKKCGKIFSSKSNFIDHKRMHSREKPYKCTECGKAFTQSAYLFDHQRLHNGEKP 649 Query: 531 Y-ASLCQVEFGNFNNLSNHSGNNVNYNASQQCQAPGVQKYEVSESDQMSGVKAESQDFIP 589 Y + C F +L H + N YE + ++ G D Sbjct: 650 YECNECGKVFILKKSLILHQRFHTGENL-----------YECKDCGKVFGSNRNLIDHER 698 Query: 590 GSTGQ------PCLPNVLLESEQSNPFCSYSEHQE-KNDVFLYRCSVCAKSFRSPSKLER 642 G+ C ++ S+ HQ+ Y+C C K+F S L Sbjct: 699 LHNGEKPYECRECGKTFIMSK-------SFMVHQKLHTQEKAYKCEDCGKAFSYNSSLLV 751 Query: 643 HYLIHAGQKPFECSVCGKTFRQAPHWKRHQLTHFKERP 680 H IH G+KPFECS CG+ F + H+ H E+P Sbjct: 752 HRRIHTGEKPFECSECGRAFSSNRNLIEHKRIHSGEKP 789 Score = 121 bits (303), Expect = 2e-27 Identities = 66/225 (29%), Positives = 110/225 (48%), Gaps = 25/225 (11%) Query: 23 RNRPYVCNICFKHFETPSKLARHYLIHTGQKPFECDVCHKTFRQLVHLERHQLTHSLP-- 80 R +PY C C K F + L H +H G+KP+EC+ C K F L HQ H+ Sbjct: 618 REKPYKCTECGKAFTQSAYLFDHQRLHNGEKPYECNECGKVFILKKSLILHQRFHTGENL 677 Query: 81 FKCSICQRHFKNLKTFVKHQQLHNETYQNNVKQVRRLLEAKQEKSMYGVYNTFTTEERWA 140 ++C C + F + + + H++LHN ++ + TF + + Sbjct: 678 YECKDCGKVFGSNRNLIDHERLHNGEKPYECRECGK---------------TFIMSKSFM 722 Query: 141 LHPCSKSDPMYSMKRRKNIHACTICGKMFPSQSKLDRHVLIHTGQRPFKCVLCTKSFRQS 200 +H + ++ + C CGK F S L H IHTG++PF+C C ++F + Sbjct: 723 VHQ--------KLHTQEKAYKCEDCGKAFSYNSSLLVHRRIHTGEKPFECSECGRAFSSN 774 Query: 201 THLKIHQLTHSEERPFQCCFCQKGFKIQSKLLKHKQIHTRNKAFR 245 +L H+ HS E+P++C C K F ++ L+ H++IHTR K+++ Sbjct: 775 RNLIEHKRIHSGEKPYECDECGKCFILKKSLIGHQRIHTREKSYK 819 Score = 118 bits (296), Expect = 2e-26 Identities = 71/229 (31%), Positives = 116/229 (50%), Gaps = 21/229 (9%) Query: 25 RPYVCNICFKHFETPSKLARHYLIHTGQKPFECDVCHKTFRQLVHLERHQLTHS--LPFK 82 +PY C+ C K F L H IHT +K ++C+ C K F +L HQ H+ P+ Sbjct: 788 KPYECDECGKCFILKKSLIGHQRIHTREKSYKCNDCGKVFSYRSNLIAHQRIHTGEKPYA 847 Query: 83 CSICQRHFKNLKTFVKHQQLHN--ETYQNNVKQVRRLLEAKQEKSMYGVYNTFTTEERWA 140 CS C + F + ++HQ++H+ +TY+ +V R++L + + ++ T E+ + Sbjct: 848 CSECGKGFTYNRNLIEHQRIHSGEKTYECHV--CRKVLTSSRNLMVH--QRIHTGEKPYK 903 Query: 141 LHPCSKSDPMYSMKRRKNIHA----------CTICGKMFPSQSKLDRHVLIHTGQRPFKC 190 + C K +S + +H C C K F S+ L H IHTG++P+ C Sbjct: 904 CNECGKD---FSQNKNLVVHQRMHTGEKPYECDKCRKSFTSKRNLVGHQRIHTGEKPYGC 960 Query: 191 VLCTKSFRQSTHLKIHQLTHSEERPFQCCFCQKGFKIQSKLLKHKQIHT 239 C+K FRQ +L +HQ H++E+P +C +K F S L ++IHT Sbjct: 961 NDCSKVFRQRKNLTVHQKIHTDEKPCECDVSEKEFSQTSNLHLQQKIHT 1009 Score = 94.7 bits (234), Expect = 2e-19 Identities = 59/203 (29%), Positives = 94/203 (46%), Gaps = 17/203 (8%) Query: 23 RNRPYVCNICFKHFETPSKLARHYLIHTGQKPFECDVCHKTFRQLVHLERHQLTHS--LP 80 R + Y CN C K F S L H IHTG+KP+ C C K F +L HQ HS Sbjct: 814 REKSYKCNDCGKVFSYRSNLIAHQRIHTGEKPYACSECGKGFTYNRNLIEHQRIHSGEKT 873 Query: 81 FKCSICQRHFKNLKTFVKHQQLHNETYQNNVKQVRRLLEAKQEKSMYGVYNTFTTEERWA 140 ++C +C++ + + + HQ++H + + + Q K++ T E+ + Sbjct: 874 YECHVCRKVLTSSRNLMVHQRIHTGEKPYKCNECGK--DFSQNKNLVVHQRMHTGEKPYE 931 Query: 141 LHPCSKSDPMYSMKRR----KNIHA------CTICGKMFPSQSKLDRHVLIHTGQRPFKC 190 C KS ++ KR + IH C C K+F + L H IHT ++P +C Sbjct: 932 CDKCRKS---FTSKRNLVGHQRIHTGEKPYGCNDCSKVFRQRKNLTVHQKIHTDEKPCEC 988 Query: 191 VLCTKSFRQSTHLKIHQLTHSEE 213 + K F Q+++L + Q H+ E Sbjct: 989 DVSEKEFSQTSNLHLQQKIHTIE 1011 Score = 89.0 bits (219), Expect = 1e-17 Identities = 88/372 (23%), Positives = 152/372 (40%), Gaps = 49/372 (13%) Query: 329 SYNYKTIVKKILAKLKRARSKKLDNFQSEKKVFKKS------FLRNCD--LISGEQSSEQ 380 S ++T+ + K + S++ D+ + K + S F C+ +++ + +E Sbjct: 255 SLEWETMTENEEVTSKPSSSQRADSHKGTSKRLQGSVPQVLDFEEECEWQVLASQWGNET 314 Query: 381 TQRTFVGSLGKHGTYKTIG--NRKKKTLTLPFSWQNMGKNLKGILTTENILSIDNSVNKK 438 +R T K + R KK T P K L LT + +S Sbjct: 315 DERA--------DTVKKVSLCERDKKKRTPPEKQGQKWKELGDSLTFGSAISE------- 359 Query: 439 DLSICGSSGEEFFNNCEVLQCGFS-----VPRENIRTRHKICPCDKCEKVFPSISKLKRH 493 S+ G+ G++F+ C++ F+ + I T K C +C K F S L H Sbjct: 360 --SLIGTEGKKFYK-CDMCCKHFNKISHLINHRRIHTGEKPHKCKECGKGFIQRSSLLMH 416 Query: 494 YLIHTGQRPFGCNICGKSFRQSAHLKRHEQTHNEKSPYASLCQVEFGNFNNLSNHSGNNV 553 H+G++P+ CN CGK+F QSA+L H++ H + PY C+ E G HSG + Sbjct: 417 LRNHSGEKPYKCNECGKAFSQSAYLLNHQRIHTGEKPYK--CK-ECGK--GFYRHSGLII 471 Query: 554 NYNASQQCQAPGVQKYEVSESDQMSGVKA---ESQDFIPGSTGQPCLPNVLLESEQSNPF 610 + G + Y+ +E ++ A + Q G C + + Sbjct: 472 HLRRHS-----GERPYKCNECGKVFSQNAYLIDHQRLHKGEEPYKCNKCQKAFILKKSLI 526 Query: 611 CSYSEHQEKNDVFLYRCSVCAKSFRSPSKLERHYLIHAGQKPFECSVCGKTFRQAPHWKR 670 H + Y+C C K+F + L H +H+ + P++C CGK F ++ Sbjct: 527 LHQRIHSGEKP---YKCDECGKTFAQTTYLIDHQRLHSAENPYKCKECGKVFIRSKSLLL 583 Query: 671 HQLTHFKERPQG 682 HQ H +++ G Sbjct: 584 HQRVHTEKKTFG 595 >gi|55769537 zinc finger protein 658 [Homo sapiens] Length = 1059 Score = 201 bits (510), Expect = 2e-51 Identities = 169/667 (25%), Positives = 276/667 (41%), Gaps = 52/667 (7%) Query: 32 CFKHFETPSKLARHYLIHTGQKPFECDVCHKTFRQLVHLERHQLTHS--LPFKCSICQRH 89 C K F + L +H H+G+K ++ + C K+F H +H T+ ++C+ C + Sbjct: 389 CRKSFYRKAHLIQHQRPHSGEKTYQYEECAKSFCSSSHPIQHPGTYVGFKLYECNECGKA 448 Query: 90 FKNLKTFVKHQQLHNETYQNNVKQVRRLLEAKQEKSMYGVYNTFTTEERWALHPCSKSDP 149 F KH ++H + + R + + G T E K+ Sbjct: 449 FCQNSNLSKHLRIHTKEKPCDNNGCGR----SYKSPLIGHQKTDAEMELCGGSEYGKTSH 504 Query: 150 MYSMKR---RKNIHACTICGKMFPSQSKLDRHVLIHTGQRPFKCVLCTKSFRQSTHLKIH 206 + +R + + C CGK F S L H IHTG++P++CV C K+F THL +H Sbjct: 505 LKGHQRILMGEKPYECIECGKTFSKTSHLRAHQRIHTGEKPYECVECEKTFSHKTHLSVH 564 Query: 207 QLTHSEERPFQCCFCQKGFKIQSKLLKHKQIHTRNKAFRALLLKKRRTESRPLP--NKLN 264 Q H+ E+P++C C K F S L H++IHT K + +K + L ++++ Sbjct: 565 QRVHTGEKPYECNDCGKSFTYNSALRAHQRIHTGEKPYECSDCEKTFAHNSALRAHHRIH 624 Query: 265 ANQGGFENGEIGESEEN-NPLDVHSIYIV---PFQCPKCEKCFESEQILNEHSCFAARSG 320 + +E E G S + + L H P++C +C + F L H +G Sbjct: 625 TGEKPYECNECGRSFAHISVLKAHQRIHTGEKPYECNECGRSFTYNSALRAHQ--RIHTG 682 Query: 321 KIPSRFKRSYNYKTIVKKILAKLKR---ARSKKLDNFQSEKKVFKKSFLR-NCDLISGEQ 376 + P ++ S KT K+ + K + + EK S LR + ++ +GE+ Sbjct: 683 RKP--YECSDCEKTFAHNSALKIHQRIHTGEKPYECNECEKTFAHNSALRAHQNIHTGEK 740 Query: 377 SSEQTQ--RTFVGSLGKHGTYKTIGNRKKKTLTLPFSWQNMGKNLKGILTTENILSIDNS 434 E ++ +TF + T++ I +K P+ GK I Sbjct: 741 LYECSECGKTFFQKT-RLSTHRRIHTGEK-----PYECSKCGKTFSQKSYLSGHERIHTG 794 Query: 435 VNKKDLSICGSSGEEFFNNCEVLQCGFSVPRENIRTRHKICPCDKCEKVFPSISKLKRHY 494 + ++CG + + + + I T K C++C K F + L H Sbjct: 795 EKPYECNVCGKT---------FVYKAALIVHQRIHTGEKPYECNQCGKTFSQRTHLCAHQ 845 Query: 495 LIHTGQRPFGCNICGKSFRQSAHLKRHEQTHNEKSPY-ASLCQVEFGNFNNLSNHSGNNV 553 IHTG++P+ CN CGK+F ++ L+ H + H + PY + C F ++L H Sbjct: 846 RIHTGEKPYECNECGKTFADNSALRAHHRIHTGEKPYECNDCGKTFSKTSHLRAHLRTRS 905 Query: 554 NYNASQQCQAPGVQKYEVSESDQMSGVKAESQDFIPGSTGQPCLPNVLLESEQSNPFCSY 613 +C G E S V + + G+P N L Q Sbjct: 906 G-EKPYECSECGKTFSEKSYVSAHQRVHTGEKPYECNVCGKPFAHNSTLRVHQR------ 958 Query: 614 SEHQEKNDVFLYRCSVCAKSFRSPSKLERHYLIHAGQKPFECSVCGKTFRQAPHWKRHQL 673 EK+ Y C+ C K+F S L H IH G+KP+EC+ CGK F Q + HQ Sbjct: 959 IHTGEKS----YECNDCGKTFSQKSHLSAHQRIHTGEKPYECNECGKAFAQNSTLRVHQR 1014 Query: 674 THFKERP 680 H E+P Sbjct: 1015 IHTGEKP 1021 Score = 187 bits (474), Expect = 4e-47 Identities = 142/540 (26%), Positives = 223/540 (41%), Gaps = 59/540 (10%) Query: 25 RPYVCNICFKHFETPSKLARHYLIHTGQKPFECDVCHKTFRQLVHLERHQLTHS--LPFK 82 +PY C C K F S L H IHTG+KP+EC C KTF HL HQ H+ P++ Sbjct: 516 KPYECIECGKTFSKTSHLRAHQRIHTGEKPYECVECEKTFSHKTHLSVHQRVHTGEKPYE 575 Query: 83 CSICQRHFKNLKTFVKHQQLHNETYQNNVKQVRRLLEAKQEKSMYGVYNTFTTEERWALH 142 C+ C + F HQ++H + ++ + T E+ + + Sbjct: 576 CNDCGKSFTYNSALRAHQRIHTGEKPYECSDCEKTF--AHNSALRAHHRIHTGEKPYECN 633 Query: 143 PCSKSDPMYS-MKRRKNIHA------CTICGKMFPSQSKLDRHVLIHTGQRPFKCVLCTK 195 C +S S +K + IH C CG+ F S L H IHTG++P++C C K Sbjct: 634 ECGRSFAHISVLKAHQRIHTGEKPYECNECGRSFTYNSALRAHQRIHTGRKPYECSDCEK 693 Query: 196 SFRQSTHLKIHQLTHSEERPFQCCFCQKGFKIQSKLLKHKQIHTRNKAFRALLLKKRRTE 255 +F ++ LKIHQ H+ E+P++C C+K F S L H+ IHT K + K + Sbjct: 694 TFAHNSALKIHQRIHTGEKPYECNECEKTFAHNSALRAHQNIHTGEKLYECSECGKTFFQ 753 Query: 256 SRPLPNKLNANQGGFENGEIGESEENNPLDVHSIYIVPFQCPKCEKCFESEQILNEHSCF 315 L + G P++C KC K F + L+ H Sbjct: 754 KTRLSTHRRIHTGE----------------------KPYECSKCGKTFSQKSYLSGHE-- 789 Query: 316 AARSGKIPSRFKRSYNYKTIVKK---ILAKLKRARSKKLDNFQSEKKVFKKSFL-RNCDL 371 +G+ P ++ + KT V K I+ + K + Q K +++ L + + Sbjct: 790 RIHTGEKP--YECNVCGKTFVYKAALIVHQRIHTGEKPYECNQCGKTFSQRTHLCAHQRI 847 Query: 372 ISGEQSSE--QTQRTFVGSLGKHGTYKTIGNRKKKTLTLPFSWQNMGKNLKGILTTENIL 429 +GE+ E + +TF + ++ K P+ + GK L Sbjct: 848 HTGEKPYECNECGKTFADNSALRAHHRIHTGEK------PYECNDCGKTFSKTSHLRAHL 901 Query: 430 SIDNSVNKKDLSICGSSGEEFFNNCEVLQCGFSVPRENIRTRHKICPCDKCEKVFPSISK 489 + + S CG + E + + + T K C+ C K F S Sbjct: 902 RTRSGEKPYECSECGKTFSE---------KSYVSAHQRVHTGEKPYECNVCGKPFAHNST 952 Query: 490 LKRHYLIHTGQRPFGCNICGKSFRQSAHLKRHEQTHNEKSPY-ASLCQVEFGNFNNLSNH 548 L+ H IHTG++ + CN CGK+F Q +HL H++ H + PY + C F + L H Sbjct: 953 LRVHQRIHTGEKSYECNDCGKTFSQKSHLSAHQRIHTGEKPYECNECGKAFAQNSTLRVH 1012 Score = 164 bits (415), Expect = 3e-40 Identities = 173/717 (24%), Positives = 285/717 (39%), Gaps = 90/717 (12%) Query: 30 NICFKHFETPSKLARHYLIHTGQKPFECDVCHKTFRQLVHLERHQLTHS-----LPFKCS 84 N C ++F S H G K E + C Q + HQ H+ L + Sbjct: 328 NKCEENFSQSSAHIVHQKTQAGDKFGEHNECTDALYQKLDFTAHQRIHTEDKFYLSDEHG 387 Query: 85 ICQRHFKNLKTFVKHQQLHN--ETYQNNVKQVRRLLEAKQEKSMYGVYNTF--------- 133 C++ F ++HQ+ H+ +TYQ + + + G Y F Sbjct: 388 KCRKSFYRKAHLIQHQRPHSGEKTYQYE-ECAKSFCSSSHPIQHPGTYVGFKLYECNECG 446 Query: 134 ----------------TTEERWALHPCSKSDPMYSMKRRKNIHACTIC-GKMFPSQSKLD 176 T E+ + C +S + +K +C G + S L Sbjct: 447 KAFCQNSNLSKHLRIHTKEKPCDNNGCGRSYKSPLIGHQKTDAEMELCGGSEYGKTSHLK 506 Query: 177 RHVLIHTGQRPFKCVLCTKSFRQSTHLKIHQLTHSEERPFQCCFCQKGFKIQSKLLKHKQ 236 H I G++P++C+ C K+F +++HL+ HQ H+ E+P++C C+K F ++ L H++ Sbjct: 507 GHQRILMGEKPYECIECGKTFSKTSHLRAHQRIHTGEKPYECVECEKTFSHKTHLSVHQR 566 Query: 237 IHTRNKAFRALLLKKRRTESRPL--PNKLNANQGGFENGEIGES-EENNPLDVHSIYIV- 292 +HT K + K T + L +++ + +E + ++ N+ L H Sbjct: 567 VHTGEKPYECNDCGKSFTYNSALRAHQRIHTGEKPYECSDCEKTFAHNSALRAHHRIHTG 626 Query: 293 --PFQCPKCEKCFESEQILNEHSCFAARSGKIP---SRFKRSYNYKTIVKKILAKLKRAR 347 P++C +C + F +L H +G+ P + RS+ Y + + + ++ R Sbjct: 627 EKPYECNECGRSFAHISVLKAHQ--RIHTGEKPYECNECGRSFTYNSAL-RAHQRIHTGR 683 Query: 348 SKKLDNFQSEKKVFKKSFLRNCDLI-SGEQSSE--QTQRTFV--GSLGKHGTYKTIGNRK 402 K + EK S L+ I +GE+ E + ++TF +L H T G + Sbjct: 684 -KPYECSDCEKTFAHNSALKIHQRIHTGEKPYECNECEKTFAHNSALRAHQNIHT-GEKL 741 Query: 403 KKTLTLPFSWQNMGKNLKGILTTENILSIDNSVNKKDLSICGSSGEEFFNNCEVLQCGFS 462 + GK I + S CG + Q + Sbjct: 742 -------YECSECGKTFFQKTRLSTHRRIHTGEKPYECSKCGKT---------FSQKSYL 785 Query: 463 VPRENIRTRHKICPCDKCEKVFPSISKLKRHYLIHTGQRPFGCNICGKSFRQSAHLKRHE 522 E I T K C+ C K F + L H IHTG++P+ CN CGK+F Q HL H+ Sbjct: 786 SGHERIHTGEKPYECNVCGKTFVYKAALIVHQRIHTGEKPYECNQCGKTFSQRTHLCAHQ 845 Query: 523 QTHNEKSPY-ASLCQVEFGNFNNLSNHSGNNVNYNASQQCQAPGVQKYEVSESDQMSGVK 581 + H + PY + C F + + L H + G + YE ++ + Sbjct: 846 RIHTGEKPYECNECGKTFADNSALRAHHRIHT-----------GEKPYECNDCGKTFSKT 894 Query: 582 AESQDFIPGSTGQPCLPNVLLESEQSNPFCSY-SEHQE-KNDVFLYRCSVCAKSFRSPSK 639 + + + +G+ P E ++ SY S HQ Y C+VC K F S Sbjct: 895 SHLRAHLRTRSGEK--PYECSECGKTFSEKSYVSAHQRVHTGEKPYECNVCGKPFAHNST 952 Query: 640 LERHYLIHAGQKPFECSVCGKTFRQAPHWKRHQLTHFKERPQ-----GKVVALDSVM 691 L H IH G+K +EC+ CGKTF Q H HQ H E+P GK A +S + Sbjct: 953 LRVHQRIHTGEKSYECNDCGKTFSQKSHLSAHQRIHTGEKPYECNECGKAFAQNSTL 1009 Score = 161 bits (408), Expect = 2e-39 Identities = 157/675 (23%), Positives = 260/675 (38%), Gaps = 95/675 (14%) Query: 27 YVCNICFKHFETPSKLARHYLIHTGQKPFECDVCHKTFR--------------------- 65 Y CN C K F S L++H IHT +KP + + C ++++ Sbjct: 440 YECNECGKAFCQNSNLSKHLRIHTKEKPCDNNGCGRSYKSPLIGHQKTDAEMELCGGSEY 499 Query: 66 -QLVHLERHQ--LTHSLPFKCSICQRHFKNLKTFVKHQQLHNETYQNNVKQVRRLLEAKQ 122 + HL+ HQ L P++C C + F HQ++H + + K Sbjct: 500 GKTSHLKGHQRILMGEKPYECIECGKTFSKTSHLRAHQRIHTGEKPYECVECEKTFSHKT 559 Query: 123 EKSMYGVYNTFTTEERWALHPCSKSDPMYS-MKRRKNIHA------CTICGKMFPSQSKL 175 S++ T E+ + + C KS S ++ + IH C+ C K F S L Sbjct: 560 HLSVH--QRVHTGEKPYECNDCGKSFTYNSALRAHQRIHTGEKPYECSDCEKTFAHNSAL 617 Query: 176 DRHVLIHTGQRPFKCVLCTKSFRQSTHLKIHQLTHSEERPFQCCFCQKGFKIQSKLLKHK 235 H IHTG++P++C C +SF + LK HQ H+ E+P++C C + F S L H+ Sbjct: 618 RAHHRIHTGEKPYECNECGRSFAHISVLKAHQRIHTGEKPYECNECGRSFTYNSALRAHQ 677 Query: 236 QIHTRNKAFRALLLKKRRTESRPLPNKLNANQGGFENGEIGESEENNPLDVHSIYIVPFQ 295 +IHT K + +K + L + G P++ Sbjct: 678 RIHTGRKPYECSDCEKTFAHNSALKIHQRIHTGE----------------------KPYE 715 Query: 296 CPKCEKCFESEQILNEHSCFAARSGKIPSRFKRSYNYKTIVKKILAKLKR---ARSKKLD 352 C +CEK F L H +G+ ++ S KT +K R K + Sbjct: 716 CNECEKTFAHNSALRAHQ--NIHTGE--KLYECSECGKTFFQKTRLSTHRRIHTGEKPYE 771 Query: 353 NFQSEKKVFKKSFLRNCDLI-SGEQSSEQTQRTFVGSLGKHGTYKT--IGNRKKKTLTLP 409 + K +KS+L + I +GE+ E GK YK I +++ T P Sbjct: 772 CSKCGKTFSQKSYLSGHERIHTGEKPYE------CNVCGKTFVYKAALIVHQRIHTGEKP 825 Query: 410 FSWQNMGKNLKGILTTENILSIDNSVNKKDLSI-CGSSGEEFFNNCEVLQCGFSVPRENI 468 + GK + L ++ + C G+ F +N + I Sbjct: 826 YECNQCGKT----FSQRTHLCAHQRIHTGEKPYECNECGKTFADNSALR------AHHRI 875 Query: 469 RTRHKICPCDKCEKVFPSISKLKRHYLIHTGQRPFGCNICGKSFRQSAHLKRHEQTHNEK 528 T K C+ C K F S L+ H +G++P+ C+ CGK+F + +++ H++ H + Sbjct: 876 HTGEKPYECNDCGKTFSKTSHLRAHLRTRSGEKPYECSECGKTFSEKSYVSAHQRVHTGE 935 Query: 529 SPY-ASLCQVEFGNFNNLSNHSGNNVNYNASQQCQAPGVQKYEVSESDQMSGVKAESQDF 587 PY ++C F + + L H + S +C G + S + + + Sbjct: 936 KPYECNVCGKPFAHNSTLRVHQRIHTG-EKSYECNDCGKTFSQKSHLSAHQRIHTGEKPY 994 Query: 588 IPGSTGQPCLPNVLLESEQSNPFCSYSEHQEKNDVFLYRCSVCAKSFRSPSKLERHYL-I 646 G+ N L Q EK Y C C K+F + L H+ + Sbjct: 995 ECNECGKAFAQNSTLRVHQR------IHTGEKP----YECDECGKTFVRKAALRVHHTRM 1044 Query: 647 HAGQKPFECSVCGKT 661 H +K C+ GK+ Sbjct: 1045 HTREKTLACNGFGKS 1059 Score = 157 bits (398), Expect = 2e-38 Identities = 133/530 (25%), Positives = 224/530 (42%), Gaps = 85/530 (16%) Query: 25 RPYVCNICFKHFETPSKLARHYLIHTGQKPFECDVCHKTFRQLVHLERHQLTHS--LPFK 82 +PY CN C K F S L H IHTG+KP+EC C KTF L H H+ P++ Sbjct: 572 KPYECNDCGKSFTYNSALRAHQRIHTGEKPYECSDCEKTFAHNSALRAHHRIHTGEKPYE 631 Query: 83 CSICQRHFKNLKTFVKHQQLH--------NE-----TYQNNVKQVRRLLEAKQEKSMYGV 129 C+ C R F ++ HQ++H NE TY + ++ +R+ ++ Sbjct: 632 CNECGRSFAHISVLKAHQRIHTGEKPYECNECGRSFTYNSALRAHQRIHTGRKPYECSDC 691 Query: 130 YNTF-------------TTEERWALHPCSKSDPMYS-MKRRKNIHA------CTICGKMF 169 TF T E+ + + C K+ S ++ +NIH C+ CGK F Sbjct: 692 EKTFAHNSALKIHQRIHTGEKPYECNECEKTFAHNSALRAHQNIHTGEKLYECSECGKTF 751 Query: 170 PSQSKLDRHVLIHTGQRPFKCVLCTKSFRQSTHLKIHQLTHSEERPFQCCFCQKGFKIQS 229 +++L H IHTG++P++C C K+F Q ++L H+ H+ E+P++C C K F ++ Sbjct: 752 FQKTRLSTHRRIHTGEKPYECSKCGKTFSQKSYLSGHERIHTGEKPYECNVCGKTFVYKA 811 Query: 230 KLLKHKQIHTRNKAFRALLLKKRRTESRPL--PNKLNANQGGFENGEIGES-EENNPLDV 286 L+ H++IHT K + K ++ L +++ + +E E G++ +N+ L Sbjct: 812 ALIVHQRIHTGEKPYECNQCGKTFSQRTHLCAHQRIHTGEKPYECNECGKTFADNSALRA 871 Query: 287 HSIYIV---PFQCPKCEKCFESEQILNEHSCFAARSGKIPSRFKRSYNYKTIVKKILAKL 343 H P++C C K F L H RSG+ P ++ S KT +K Sbjct: 872 HHRIHTGEKPYECNDCGKTFSKTSHLRAH--LRTRSGEKP--YECSECGKTFSEK----- 922 Query: 344 KRARSKKLDNFQSEKKVFKKSFLRNCDLISGEQSSEQTQRTFVGSLGKHGTYKTIGNRKK 403 + ++V C++ + T R +++ Sbjct: 923 --------SYVSAHQRVHTGEKPYECNVCGKPFAHNSTLRV---------------HQRI 959 Query: 404 KTLTLPFSWQNMGKNLKGILTTENILSIDNSVNKKDLSI-CGSSGEEFFNNCEVLQCGFS 462 T + + GK + ++ LS ++ + C G+ F N + Sbjct: 960 HTGEKSYECNDCGKT----FSQKSHLSAHQRIHTGEKPYECNECGKAFAQNSTLR----- 1010 Query: 463 VPRENIRTRHKICPCDKCEKVFPSISKLKRHYL-IHTGQRPFGCNICGKS 511 + I T K CD+C K F + L+ H+ +HT ++ CN GKS Sbjct: 1011 -VHQRIHTGEKPYECDECGKTFVRKAALRVHHTRMHTREKTLACNGFGKS 1059 Score = 46.2 bits (108), Expect = 1e-04 Identities = 50/238 (21%), Positives = 77/238 (32%), Gaps = 67/238 (28%) Query: 498 TGQRPFGCNICGKSFRQ-SAHLKRHEQTHNEKSPYASLCQVEFGNFNNLSNHSGNNVNYN 556 TG F N C ++F Q SAH+ + +K FG N ++ +++ Sbjct: 320 TGWSAFESNKCEENFSQSSAHIVHQKTQAGDK----------FGEHNECTDALYQKLDFT 369 Query: 557 ASQQCQAPGVQKYEVSESDQMSGVKAESQDFIPGSTGQPCLPNVLLESEQSNPFCSYSEH 616 A Q+ K+ +S+ + + E + FCS S Sbjct: 370 AHQRIHTE--DKFYLSDEHGKCRKSFYRKAHLIQHQRPHSGEKTYQYEECAKSFCSSSHP 427 Query: 617 QEKNDVF----LYRCSVCAKSFRSPSKLERHYLIHA------------------------ 648 + + LY C+ C K+F S L +H IH Sbjct: 428 IQHPGTYVGFKLYECNECGKAFCQNSNLSKHLRIHTKEKPCDNNGCGRSYKSPLIGHQKT 487 Query: 649 --------------------------GQKPFECSVCGKTFRQAPHWKRHQLTHFKERP 680 G+KP+EC CGKTF + H + HQ H E+P Sbjct: 488 DAEMELCGGSEYGKTSHLKGHQRILMGEKPYECIECGKTFSKTSHLRAHQRIHTGEKP 545 >gi|68303809 zinc finger protein 43 [Homo sapiens] Length = 809 Score = 199 bits (506), Expect = 7e-51 Identities = 174/694 (25%), Positives = 279/694 (40%), Gaps = 95/694 (13%) Query: 14 QCVVANKLPRNRPYVCNICFKHFETPSKLARHYLIHTGQKPFECDVCHKTFRQLVHLERH 73 QC+ A + ++ ++ + C K F S RH + HT +K F+C C K+F L HL +H Sbjct: 136 QCLPATQ---SKIFLFDKCVKAFHKFSNSNRHKISHTEKKLFKCKECGKSFCMLPHLAQH 192 Query: 74 QLTHSLP--FKCSICQRHFKNLKTFVKHQQLHNETYQNNVKQVRRLLEAKQEKSMYGVYN 131 ++ H+ KC C + F KH++++ ++ ++ Sbjct: 193 KIIHTRVNFCKCEKCGKAFNCPSIITKHKRINTGEKPYTCEECGKV-------------- 238 Query: 132 TFTTEERWALHPCSKSDPMYSMKRRKNIHACTICGKMFPSQSKLDRHVLIHTGQRPFKCV 191 F R H + + R ++ C CGK F S L H +I TG++ +KC Sbjct: 239 -FNWSSRLTTHKKNYT--------RYKLYKCEECGKAFNKSSILTTHKIIRTGEKFYKCK 289 Query: 192 LCTKSFRQSTHLKIHQLTHSEERPFQCCFCQKGFKIQSKLLKHKQIHTRNKAFRALLLKK 251 C K+F QS++L H+ H E+P++C C K F S L KHK+IHT K + K Sbjct: 290 ECAKAFNQSSNLTEHKKIHPGEKPYKCEECGKAFNWPSTLTKHKRIHTGEKPYTCEECGK 349 Query: 252 RRTESRPLP--NKLNANQGGFENGEIGE--SEENNPLDVHSIYI--VPFQCPKCEKCFES 305 + L +++ + ++ E GE S +N I+ P++C +C K F+ Sbjct: 350 AFNQFSNLTTHKRIHTAEKFYKCTECGEAFSRSSNLTKHKKIHTEKKPYKCEECGKAFKW 409 Query: 306 EQILNEHSCF-----------AARSGKIPSRFKRSYNYKTIVKKILAKLKRARSKKLDNF 354 L EH ++ PS + T K ++ + N Sbjct: 410 SSKLTEHKLTHTGEKPYKCEECGKAFNWPSTLTKHNRIHTGEKPYKCEVCGKAFNQFSNL 469 Query: 355 QSEKKVFKKSFLRNCDLISGEQSSEQTQRTFVGSLGKHGTYKTIGNRKKKTLTLPFSWQN 414 + K++ C E+ + R+ +L KH K I KK P+ + Sbjct: 470 TTHKRIHTAEKPYKC-----EECGKAFSRS--SNLTKH---KKIHIEKK-----PYKCEE 514 Query: 415 MGKNLK--GILTTENILSIDNSVNKKDLSICGSSGEEFFNNCEVLQCGFSVPRENIRTRH 472 GK K LT I K CG + FN+ +L + I T Sbjct: 515 CGKAFKWSSKLTEHKITHTGEKPYK--CEECGKA----FNHFSIL-----TKHKRIHTGE 563 Query: 473 KICPCDKCEKVFPSISKLKRHYLIHTGQRPFGCNICGKSFRQSAHLKRHEQTHNEKSPY- 531 K C++C K F S L H IHTG++ + C CGK+F QS++L H++ H PY Sbjct: 564 KPYKCEECGKAFTQSSNLTTHKKIHTGEKFYKCEECGKAFTQSSNLTTHKKIHTGGKPYK 623 Query: 532 ASLCQVEFGNFNNLSNHSGNNVNYNASQQCQAPGVQKYEVSESDQMSGVKAESQDFIPGS 591 C F F+ L+ H + +C+ E ++ + S + + G Sbjct: 624 CEECGKAFNQFSTLTKHKIIHTE-EKPYKCE-------ECGKAFKWSSTLTKHKIIHTGE 675 Query: 592 TGQPCLPNVLLESEQSNPFCSYSEHQEKNDVF-----LYRCSVCAKSFRSPSKLERHYLI 646 C E+ S + + Y+C C K+F S L H I Sbjct: 676 KPYKC--------EECGKAFKLSSTLSTHKIIHTGEKPYKCEKCGKAFNRSSNLIEHKKI 727 Query: 647 HAGQKPFECSVCGKTFRQAPHWKRHQLTHFKERP 680 H G++P++C CGK F + H H+ H KE+P Sbjct: 728 HTGEQPYKCEECGKAFNYSSHLNTHKRIHTKEQP 761 Score = 196 bits (498), Expect = 6e-50 Identities = 154/571 (26%), Positives = 252/571 (44%), Gaps = 87/571 (15%) Query: 23 RNRPYVCNICFKHFETPSKLARHYLIHTGQKPFECDVCHKTFRQLVHLERHQLTH--SLP 80 R + Y C C K F S L H +I TG+K ++C C K F Q +L H+ H P Sbjct: 254 RYKLYKCEECGKAFNKSSILTTHKIIRTGEKFYKCKECAKAFNQSSNLTEHKKIHPGEKP 313 Query: 81 FKCSICQRHFKNLKTFVKHQQLHNETYQNNVKQVRRLLEAKQEKSMYGVYNTFTTEERWA 140 +KC C + F T KH+++H ++ + + ++ TT +R Sbjct: 314 YKCEECGKAFNWPSTLTKHKRIHTGEKPYTCEECGKA---------FNQFSNLTTHKR-- 362 Query: 141 LHPCSKSDPMYSMKRRKNIHACTICGKMFPSQSKLDRHVLIHTGQRPFKCVLCTKSFRQS 200 +H K + CT CG+ F S L +H IHT ++P+KC C K+F+ S Sbjct: 363 IHTAEK------------FYKCTECGEAFSRSSNLTKHKKIHTEKKPYKCEECGKAFKWS 410 Query: 201 THLKIHQLTHSEERPFQCCFCQKGFKIQSKLLKHKQIHTRNKAFRALLLKKRRTESRPLP 260 + L H+LTH+ E+P++C C K F S L KH +IHT K ++ + K + L Sbjct: 411 SKLTEHKLTHTGEKPYKCEECGKAFNWPSTLTKHNRIHTGEKPYKCEVCGKAFNQFSNLT 470 Query: 261 --NKLNANQGGFENGEIGE--SEENNPLDVHSIYI--VPFQCPKCEKCFESEQILNEHSC 314 +++ + ++ E G+ S +N I+I P++C +C K F+ L EH Sbjct: 471 THKRIHTAEKPYKCEECGKAFSRSSNLTKHKKIHIEKKPYKCEECGKAFKWSSKLTEHK- 529 Query: 315 FAARSGKIPSRFK---RSYNYKTIV---KKILAKLKRARSKKL-------DNFQSEKKVF 361 +G+ P + + +++N+ +I+ K+I K + ++ N + KK+ Sbjct: 530 -ITHTGEKPYKCEECGKAFNHFSILTKHKRIHTGEKPYKCEECGKAFTQSSNLTTHKKIH 588 Query: 362 KKSFLRNCDLI--SGEQSSEQTQRTFVGSLGKHGTYKTIGNRKKKTLTL----------- 408 C+ + QSS T + + GK + G + TL Sbjct: 589 TGEKFYKCEECGKAFTQSSNLTTHKKIHTGGKPYKCEECGKAFNQFSTLTKHKIIHTEEK 648 Query: 409 PFSWQNMGKNLK--GILTTENILSIDNSVNKKDLSICGSSGEEFFNNCEVLQCGFSVPRE 466 P+ + GK K LT I+ +GE+ + CE +CG + Sbjct: 649 PYKCEECGKAFKWSSTLTKHKII---------------HTGEKPY-KCE--ECGKAFKLS 690 Query: 467 NIRTRHKIC-------PCDKCEKVFPSISKLKRHYLIHTGQRPFGCNICGKSFRQSAHLK 519 + + HKI C+KC K F S L H IHTG++P+ C CGK+F S+HL Sbjct: 691 STLSTHKIIHTGEKPYKCEKCGKAFNRSSNLIEHKKIHTGEQPYKCEECGKAFNYSSHLN 750 Query: 520 RHEQTHNEKSPY-ASLCQVEFGNFNNLSNHS 549 H++ H ++ PY C F ++NL+ H+ Sbjct: 751 THKRIHTKEQPYKCKECGKAFNQYSNLTTHN 781 Score = 182 bits (461), Expect = 1e-45 Identities = 142/538 (26%), Positives = 225/538 (41%), Gaps = 84/538 (15%) Query: 22 PRNRPYVCNICFKHFETPSKLARHYLIHTGQKPFECDVCHKTFRQLVHLERHQLTHSLP- 80 P +PY C C K F PS L +H IHTG+KP+ C+ C K F Q +L H+ H+ Sbjct: 309 PGEKPYKCEECGKAFNWPSTLTKHKRIHTGEKPYTCEECGKAFNQFSNLTTHKRIHTAEK 368 Query: 81 -FKCSICQRHFKNLKTFVKHQQLHNETYQNNVKQVRRLLEAKQEKSMYGVYNTFTTEERW 139 +KC+ C F KH+++H E ++ + + + + + + T T E+ + Sbjct: 369 FYKCTECGEAFSRSSNLTKHKKIHTEKKPYKCEECGKAFKWSSKLTEHKL--THTGEKPY 426 Query: 140 ALHPCSKSDPMYSMKRRKN-IHA------CTICGKMFPSQSKLDRHVLIHTGQRPFKCVL 192 C K+ S + N IH C +CGK F S L H IHT ++P+KC Sbjct: 427 KCEECGKAFNWPSTLTKHNRIHTGEKPYKCEVCGKAFNQFSNLTTHKRIHTAEKPYKCEE 486 Query: 193 CTKSFRQSTHLKIHQLTHSEERPFQCCFCQKGFKIQSKLLKHKQIHTRNKAFR------- 245 C K+F +S++L H+ H E++P++C C K FK SKL +HK HT K ++ Sbjct: 487 CGKAFSRSSNLTKHKKIHIEKKPYKCEECGKAFKWSSKLTEHKITHTGEKPYKCEECGKA 546 Query: 246 ----ALLLKKRRTESRPLPNKLNANQGGFENGEIGESEENNPLDVHSIYIVP--FQCPKC 299 ++L K +R + P K F ++ +N I+ ++C +C Sbjct: 547 FNHFSILTKHKRIHTGEKPYKCEECGKAF-------TQSSNLTTHKKIHTGEKFYKCEEC 599 Query: 300 EKCFESEQILNEHSCF--AARSGKIPSRFKRSYNYKTIVKKILAKLKRARSKKLDNFQSE 357 K F L H + K K + T+ K + +E Sbjct: 600 GKAFTQSSNLTTHKKIHTGGKPYKCEECGKAFNQFSTLTKHKI-------------IHTE 646 Query: 358 KKVFKKSFLRNCDLISGEQSSEQTQRTFVGS--LGKHGTYKTIGNRKKKTLTLPFSWQNM 415 +K +K E+ + F S L KH K I +K P+ + Sbjct: 647 EKPYK---------------CEECGKAFKWSSTLTKH---KIIHTGEK-----PYKCEEC 683 Query: 416 GK--NLKGILTTENILSIDNSVNKKDLSICGSSGEEFFNNCEVLQCGFSVPRENIRTRHK 473 GK L L+T I+ K C G+ F + +++ + I T + Sbjct: 684 GKAFKLSSTLSTHKIIHTGEKPYK-----CEKCGKAFNRSSNLIE------HKKIHTGEQ 732 Query: 474 ICPCDKCEKVFPSISKLKRHYLIHTGQRPFGCNICGKSFRQSAHLKRHEQTHNEKSPY 531 C++C K F S L H IHT ++P+ C CGK+F Q ++L H + H + Y Sbjct: 733 PYKCEECGKAFNYSSHLNTHKRIHTKEQPYKCKECGKAFNQYSNLTTHNKIHTGEKLY 790 Score = 155 bits (393), Expect = 9e-38 Identities = 155/655 (23%), Positives = 252/655 (38%), Gaps = 115/655 (17%) Query: 50 TGQKPFECDVCHKTFRQLVHLERHQLTHSLP--FKCSICQRHFKNLKTFVKHQQLHNETY 107 T K F D C K F + + RH+++H+ FKC C + F L +H+ +H Sbjct: 141 TQSKIFLFDKCVKAFHKFSNSNRHKISHTEKKLFKCKECGKSFCMLPHLAQHKIIHTRV- 199 Query: 108 QNNVKQVRRLLEAKQEKSMYGVYNTFTTEERWALHPCSKSDPMYSMKRRKNIHACTICGK 167 N + + +A S+ + T E+ + C CGK Sbjct: 200 --NFCKCEKCGKAFNCPSIITKHKRINTGEK--------------------PYTCEECGK 237 Query: 168 MFPSQSKLDRHVLIHTGQRPFKCVLCTKSFRQSTHLKIHQLTHSEERPFQCCFCQKGFKI 227 +F S+L H +T + +KC C K+F +S+ L H++ + E+ ++C C K F Sbjct: 238 VFNWSSRLTTHKKNYTRYKLYKCEECGKAFNKSSILTTHKIIRTGEKFYKCKECAKAFNQ 297 Query: 228 QSKLLKHKQIHTRNKAFRALLLKKRRTESRPLPNKLNANQGGFENGEIGESEENNPLDVH 287 S L +HK+IH K ++ + ++ P+ L ++ GE Sbjct: 298 SSNLTEHKKIHPGEKPYKC----EECGKAFNWPSTLTKHKR-IHTGE------------- 339 Query: 288 SIYIVPFQCPKCEKCFESEQILNEHSCFAARSGKIPSRFKRSYNYKTIVKKILAKLKRAR 347 P+ C +C K F L H KR + + K +R Sbjct: 340 ----KPYTCEECGKAFNQFSNLTTH--------------KRIHTAEKFYKCTECGEAFSR 381 Query: 348 SKKLDNFQ---SEKKVFKKSFLRNCDLISGEQSSEQTQRTFVGSLGKHGTYKTIGNRKKK 404 S L + +EKK +K E+ + F S K ++ Sbjct: 382 SSNLTKHKKIHTEKKPYK---------------CEECGKAFKWSS------KLTEHKLTH 420 Query: 405 TLTLPFSWQNMGK--NLKGILTTENILSIDNSVNKKDLSICGSSGEEFFNNCEVLQCGFS 462 T P+ + GK N LT N + K + +CG + +F N Sbjct: 421 TGEKPYKCEECGKAFNWPSTLTKHNRIHTGEKPYKCE--VCGKAFNQFSN---------L 469 Query: 463 VPRENIRTRHKICPCDKCEKVFPSISKLKRHYLIHTGQRPFGCNICGKSFRQSAHLKRHE 522 + I T K C++C K F S L +H IH ++P+ C CGK+F+ S+ L H+ Sbjct: 470 TTHKRIHTAEKPYKCEECGKAFSRSSNLTKHKKIHIEKKPYKCEECGKAFKWSSKLTEHK 529 Query: 523 QTHNEKSPY-ASLCQVEFGNFNNLSNHSGNNVNYNASQQCQAPGVQKYEVSESDQMSGVK 581 TH + PY C F +F+ L+ H + +C+ G K S+ + K Sbjct: 530 ITHTGEKPYKCEECGKAFNHFSILTKHKRIHTG-EKPYKCEECG--KAFTQSSNLTTHKK 586 Query: 582 AESQDFIPGSTGQPCLPNVLLESEQSNPFCSYSEHQEKNDVFLYRCSVCAKSFRSPSKLE 641 + G C ++ SN H Y+C C K+F S L Sbjct: 587 IHT-----GEKFYKCEECGKAFTQSSNLTTHKKIHTGGKP---YKCEECGKAFNQFSTLT 638 Query: 642 RHYLIHAGQKPFECSVCGKTFRQAPHWKRHQLTHFKERPQ-----GKVVALDSVM 691 +H +IH +KP++C CGK F+ + +H++ H E+P GK L S + Sbjct: 639 KHKIIHTEEKPYKCEECGKAFKWSSTLTKHKIIHTGEKPYKCEECGKAFKLSSTL 693 Score = 142 bits (358), Expect = 1e-33 Identities = 76/230 (33%), Positives = 115/230 (50%), Gaps = 11/230 (4%) Query: 25 RPYVCNICFKHFETPSKLARHYLIHTGQKPFECDVCHKTFRQLVHLERHQLTHS--LPFK 82 +PY C C K F S L H IHTG+K ++C+ C K F Q +L H+ H+ P+K Sbjct: 564 KPYKCEECGKAFTQSSNLTTHKKIHTGEKFYKCEECGKAFTQSSNLTTHKKIHTGGKPYK 623 Query: 83 CSICQRHFKNLKTFVKHQQLHNETYQNNVKQVRRLLEAKQEKSMYGVYNTFTTEERWALH 142 C C + F T KH+ +H E ++ + + + + + +T E+ + Sbjct: 624 CEECGKAFNQFSTLTKHKIIHTEEKPYKCEECGKAFKWSSTLTKHKIIHT--GEKPYKCE 681 Query: 143 PCSKSDPMYS-MKRRKNIHA------CTICGKMFPSQSKLDRHVLIHTGQRPFKCVLCTK 195 C K+ + S + K IH C CGK F S L H IHTG++P+KC C K Sbjct: 682 ECGKAFKLSSTLSTHKIIHTGEKPYKCEKCGKAFNRSSNLIEHKKIHTGEQPYKCEECGK 741 Query: 196 SFRQSTHLKIHQLTHSEERPFQCCFCQKGFKIQSKLLKHKQIHTRNKAFR 245 +F S+HL H+ H++E+P++C C K F S L H +IHT K ++ Sbjct: 742 AFNYSSHLNTHKRIHTKEQPYKCKECGKAFNQYSNLTTHNKIHTGEKLYK 791 Score = 85.9 bits (211), Expect = 1e-16 Identities = 65/251 (25%), Positives = 105/251 (41%), Gaps = 27/251 (10%) Query: 452 NNCEVLQCGFSVPRENI-RTRHKICPCDKCEKVFPSISKLKRHYLIHTGQRPFGCNICGK 510 + C+V + G++ + + T+ KI DKC K F S RH + HT ++ F C CGK Sbjct: 122 DECKVHRGGYNGFNQCLPATQSKIFLFDKCVKAFHKFSNSNRHKISHTEKKLFKCKECGK 181 Query: 511 SFRQSAHLKRHEQTHN-------EKSPYASLC--------QVEFGNFNNLSNHSGNNVNY 555 SF HL +H+ H EK A C ++ G G N+ Sbjct: 182 SFCMLPHLAQHKIIHTRVNFCKCEKCGKAFNCPSIITKHKRINTGEKPYTCEECGKVFNW 241 Query: 556 NASQQCQAPGVQKYEVSESDQ------MSGVKAESQDFIPGSTGQPCLPNVLLESEQSNP 609 ++ +Y++ + ++ S + + G C ++ SN Sbjct: 242 SSRLTTHKKNYTRYKLYKCEECGKAFNKSSILTTHKIIRTGEKFYKCKECAKAFNQSSN- 300 Query: 610 FCSYSEHQEKN-DVFLYRCSVCAKSFRSPSKLERHYLIHAGQKPFECSVCGKTFRQAPHW 668 +EH++ + Y+C C K+F PS L +H IH G+KP+ C CGK F Q + Sbjct: 301 ---LTEHKKIHPGEKPYKCEECGKAFNWPSTLTKHKRIHTGEKPYTCEECGKAFNQFSNL 357 Query: 669 KRHQLTHFKER 679 H+ H E+ Sbjct: 358 TTHKRIHTAEK 368 Score = 33.1 bits (74), Expect = 0.88 Identities = 14/34 (41%), Positives = 19/34 (55%) Query: 23 RNRPYVCNICFKHFETPSKLARHYLIHTGQKPFE 56 + +PY C C K F S L H IHTG+K ++ Sbjct: 758 KEQPYKCKECGKAFNQYSNLTTHNKIHTGEKLYK 791 >gi|14211907 zinc finger protein 347 [Homo sapiens] Length = 839 Score = 199 bits (506), Expect = 7e-51 Identities = 145/539 (26%), Positives = 235/539 (43%), Gaps = 53/539 (9%) Query: 23 RNRPYVCNICFKHFETPSKLARHYLIHTGQKPFECDVCHKTFRQLVHLERHQLTHS--LP 80 + +PY C C K F T S L H +IHTG+K ++C+ C K F + L +HQ H+ P Sbjct: 285 KEKPYKCYECGKAFRTRSNLTTHQVIHTGEKRYKCNECGKVFSRNSQLSQHQKIHTGEKP 344 Query: 81 FKCSICQRHFKNLKTFVKHQQLHNETYQNNVKQVRRLLEAKQEKSMYGVYNTFTTEERWA 140 +KC+ C + F V+H+ +H + + A+ +++ T + E+ + Sbjct: 345 YKCNECGKVFTQNSHLVRHRGIHTGEKPYKCNECGKAFRARSSLAIHQA--THSGEKPYK 402 Query: 141 LHPCSKSDPMYS-MKRRKNIHA------CTICGKMFPSQSKLDRHVLIHTGQRPFKCVLC 193 + C K S + IH C CGK F +S L H++IHTG++P+KC C Sbjct: 403 CNECGKVFTQNSHLTNHWRIHTGEKPYKCNECGKAFGVRSSLAIHLVIHTGEKPYKCHEC 462 Query: 194 TKSFRQSTHLKIHQLTHSEERPFQCCFCQKGFKIQSKLLKHKQIHTRNKAFRALLLKKRR 253 K FR+++HL HQL H+ E+P++C C K F+ S L H+ IHT K ++ K Sbjct: 463 GKVFRRNSHLARHQLIHTGEKPYKCNECGKAFRAHSNLTTHQVIHTGEKPYKCNECGKVF 522 Query: 254 TESRPLPNKLNANQGGFENGEIGESEENNPLDVHSIYIVPFQCPKCEKCFESEQILNEHS 313 T++ L N + G + P+ C +C K F L H Sbjct: 523 TQNSHLANHQRIHTG----------------------VKPYMCNECGKAFSVYSSLTTHQ 560 Query: 314 CFAARSGKIPSRFKRSYNYKTIVKKILAKLKRARSKKLDNFQSEKKVFK-KSFL-RNCDL 371 +G+ P + T + +K KVF+ S+L R+ + Sbjct: 561 VI--HTGEKPYKCNECGKVFTQNSHLARHRGIHTGEKPYKCNECGKVFRHNSYLSRHQRI 618 Query: 372 ISGEQSSEQTQRTFVGSLGKHGTYKTIGNRKKKTLTLPFSWQNMGKNLKGILTTENILSI 431 +GE+ + + + + +H T ++ T P+ GK + T + L+ Sbjct: 619 HTGEKPYKYNE--YGKAFSEHSNLTT--HQVIHTGEKPYKCNECGK----VFTQNSHLAR 670 Query: 432 DNSVNKKDLSI-CGSSGEEFFNNCEVLQCGFSVPRENIRTRHKICPCDKCEKVFPSISKL 490 V+ C G+ F ++ + + + T K C++C K F S L Sbjct: 671 HRRVHTGGKPYQCNECGKAFSQTSKLAR------HQRVHTGEKPYECNQCGKAFSVRSSL 724 Query: 491 KRHYLIHTGQRPFGCNICGKSFRQSAHLKRHEQTHNEKSPY-ASLCQVEFGNFNNLSNH 548 H IHTG++P+ CN CGK F Q++HL RH H + PY + C F + L+ H Sbjct: 725 TTHQAIHTGKKPYKCNECGKVFTQNSHLARHRGIHTGEKPYKCNECGKAFSQTSKLARH 783 Score = 193 bits (491), Expect = 4e-49 Identities = 173/657 (26%), Positives = 258/657 (39%), Gaps = 134/657 (20%) Query: 47 LIHTGQK------PFECDVCHKTFRQLVHLERHQLTHSL--PFKCSICQRHFKNLKTFVK 98 L+ GQK P++ D C F Q HL HQ +H+ P+KC C + F+ Sbjct: 247 LLTQGQKANNWGSPYKSDGCGMVFPQNSHLASHQRSHTKEKPYKCYECGKAFRTRSNLTT 306 Query: 99 HQQLHNETYQNNVKQVRRLLEAKQEKSMYGVYNTFTTEERWALHPCSKSDPMYS-MKRRK 157 HQ +H T E+R+ + C K S + + + Sbjct: 307 HQVIH------------------------------TGEKRYKCNECGKVFSRNSQLSQHQ 336 Query: 158 NIHA------CTICGKMFPSQSKLDRHVLIHTGQRPFKCVLCTKSFRQSTHLKIHQLTHS 211 IH C CGK+F S L RH IHTG++P+KC C K+FR + L IHQ THS Sbjct: 337 KIHTGEKPYKCNECGKVFTQNSHLVRHRGIHTGEKPYKCNECGKAFRARSSLAIHQATHS 396 Query: 212 EERPFQCCFCQKGFKIQSKLLKHKQIHTRNKAFRALLLKKRRTESRPLPNKLNANQGG-- 269 E+P++C C K F S L H +IHT K ++ K L L + G Sbjct: 397 GEKPYKCNECGKVFTQNSHLTNHWRIHTGEKPYKCNECGKAFGVRSSLAIHLVIHTGEKP 456 Query: 270 FENGEIGES-EENNPLDVHSIYIV---PFQCPKCEKCFESEQILNEHSCFAARSGKIPSR 325 ++ E G+ N+ L H + P++C +C K F + L H +G+ P + Sbjct: 457 YKCHECGKVFRRNSHLARHQLIHTGEKPYKCNECGKAFRAHSNLTTHQVI--HTGEKPYK 514 Query: 326 FKRSYNYKTIVKKILAKLKRARSKKLDNFQSEKKVFKKSFLRNCDLISGEQSSEQTQRTF 385 T ++ L N Q K C G+ S + T Sbjct: 515 CNECGKVFT------------QNSHLANHQRIHTGVKPYMCNEC----GKAFSVYSSLT- 557 Query: 386 VGSLGKHGTYKTIGNRKKKTLTLPFSWQNMGKNLKGILTTENILSIDNSVNKKDLSI-CG 444 T++ I +K P+ GK + T + L+ ++ + C Sbjct: 558 --------THQVIHTGEK-----PYKCNECGK----VFTQNSHLARHRGIHTGEKPYKCN 600 Query: 445 SSGEEFFNNCEVLQCGFSVPRENIRTRHKICPCDKCEKVFPSISKLKRHYLIHTGQRPFG 504 G+ F +N + + + I T K ++ K F S L H +IHTG++P+ Sbjct: 601 ECGKVFRHNSYLSR------HQRIHTGEKPYKYNEYGKAFSEHSNLTTHQVIHTGEKPYK 654 Query: 505 CNICGKSFRQSAHLKRHEQTHNEKSPY-ASLCQVEFGNFNNLSNHSGNNVNYNASQQCQA 563 CN CGK F Q++HL RH + H PY + C F + L+ H Q Sbjct: 655 CNECGKVFTQNSHLARHRRVHTGGKPYQCNECGKAFSQTSKLARH-----------QRVH 703 Query: 564 PGVQKYEVSESDQMSGVKAESQDFIPGSTGQPCLPNVLLESEQSNPFCSYSEHQEKNDVF 623 G + YE ++ + V++ TG+ Sbjct: 704 TGEKPYECNQCGKAFSVRSSLTTHQAIHTGKKP--------------------------- 736 Query: 624 LYRCSVCAKSFRSPSKLERHYLIHAGQKPFECSVCGKTFRQAPHWKRHQLTHFKERP 680 Y+C+ C K F S L RH IH G+KP++C+ CGK F Q RHQ H E+P Sbjct: 737 -YKCNECGKVFTQNSHLARHRGIHTGEKPYKCNECGKAFSQTSKLARHQRIHTGEKP 792 Score = 185 bits (469), Expect = 1e-46 Identities = 164/674 (24%), Positives = 260/674 (38%), Gaps = 153/674 (22%) Query: 26 PYVCNICFKHFETPSKLARHYLIHTGQKPFECDVCHKTFRQLVHLERHQLTHS------- 78 PY + C F S LA H HT +KP++C C K FR +L HQ+ H+ Sbjct: 260 PYKSDGCGMVFPQNSHLASHQRSHTKEKPYKCYECGKAFRTRSNLTTHQVIHTGEKRYKC 319 Query: 79 -----------------------LPFKCSICQRHFKNLKTFVKHQQLHNETYQNNVKQVR 115 P+KC+ C + F V+H+ +H + Sbjct: 320 NECGKVFSRNSQLSQHQKIHTGEKPYKCNECGKVFTQNSHLVRHRGIHTGEKPYKCNECG 379 Query: 116 RLLEAKQEKSMYGVYNTFTTEERWALHPCSKSDPMYS-MKRRKNIHA------CTICGKM 168 + A+ +++ T + E+ + + C K S + IH C CGK Sbjct: 380 KAFRARSSLAIHQA--THSGEKPYKCNECGKVFTQNSHLTNHWRIHTGEKPYKCNECGKA 437 Query: 169 FPSQSKLDRHVLIHTGQRPFKCVLCTKSFRQSTHLKIHQLTHSEERPFQCCFCQKGFKIQ 228 F +S L H++IHTG++P+KC C K FR+++HL HQL H+ E+P++C C K F+ Sbjct: 438 FGVRSSLAIHLVIHTGEKPYKCHECGKVFRRNSHLARHQLIHTGEKPYKCNECGKAFRAH 497 Query: 229 SKLLKHKQIHTRNKAFRALLLKKRRTESRPLPNKLNANQGGFENGEIGESEENNPLDVHS 288 S L H+ IHT K ++ K T++ L N + G Sbjct: 498 SNLTTHQVIHTGEKPYKCNECGKVFTQNSHLANHQRIHTG-------------------- 537 Query: 289 IYIVPFQCPKCEKCFESEQILNEHSCFAARSGKIPSRFKRSYNYKTIVKKILAKLKRARS 348 + P+ C +C K F L H +G+ P + Sbjct: 538 --VKPYMCNECGKAFSVYSSLTTHQ--VIHTGEKPYKCNEC------------------- 574 Query: 349 KKLDNFQSEKKVFKKS--FLRNCDLISGEQSSEQTQRTFVGSLGKHGTYKTIGNRKKKTL 406 KVF ++ R+ + +GE+ + + G + +H +Y + +++ T Sbjct: 575 ---------GKVFTQNSHLARHRGIHTGEKPYKCNE---CGKVFRHNSYLS-RHQRIHTG 621 Query: 407 TLPFSWQNMGKNLK--GILTTENILSIDNSVNKKDLSICGSSGEEFFNNCEVLQCGFSVP 464 P+ + GK LTT ++ K C G+ F N + + Sbjct: 622 EKPYKYNEYGKAFSEHSNLTTHQVIHTGEKPYK-----CNECGKVFTQNSHLAR------ 670 Query: 465 RENIRTRHKICPCDKCEKVFPSISKLKRHYLIHTGQRPFGCNICGKSFRQSAHLKRHEQT 524 + T K C++C K F SKL RH +HTG++P+ CN CGK+F + L H+ Sbjct: 671 HRRVHTGGKPYQCNECGKAFSQTSKLARHQRVHTGEKPYECNQCGKAFSVRSSLTTHQAI 730 Query: 525 HNEKSPY-ASLCQVEFGNFNNLSNHSGNNVNYNASQQCQAPGVQKYEVSESDQMSGVKAE 583 H K PY + C F ++L+ H G + G + Y+ +E KA Sbjct: 731 HTGKKPYKCNECGKVFTQNSHLARHRGIHT-----------GEKPYKCNECG-----KAF 774 Query: 584 SQDFIPGSTGQPCLPNVLLESEQSNPFCSYSEHQEKNDVFLYRCSVCAKSFRSPSKLERH 643 SQ + HQ + + C K F S L H Sbjct: 775 SQT------------------------SKLARHQRIHTG--EKPYECGKPFSICSSLTTH 808 Query: 644 YLIHAGQKPFECSV 657 IH G KP++C+V Sbjct: 809 QTIHTGGKPYKCNV 822 Score = 171 bits (434), Expect = 2e-42 Identities = 140/523 (26%), Positives = 207/523 (39%), Gaps = 83/523 (15%) Query: 25 RPYVCNICFKHFETPSKLARHYLIHTGQKPFECDVCHKTFRQLVHLERHQLTHS--LPFK 82 +PY CN C K F S L RH IHTG+KP++C+ C K FR L HQ THS P+K Sbjct: 343 KPYKCNECGKVFTQNSHLVRHRGIHTGEKPYKCNECGKAFRARSSLAIHQATHSGEKPYK 402 Query: 83 CSICQRHFKNLKTFVKHQQLHNETYQNNVKQVRRLLEAKQEKSMYGVYNTFTTEERWALH 142 C+ C + F H ++H + + + +++ V +T E+ + H Sbjct: 403 CNECGKVFTQNSHLTNHWRIHTGEKPYKCNECGKAFGVRSSLAIHLVIHT--GEKPYKCH 460 Query: 143 PCSKSDPMYS-MKRRKNIHA------CTICGKMFPSQSKLDRHVLIHTGQRPFKCVLCTK 195 C K S + R + IH C CGK F + S L H +IHTG++P+KC C K Sbjct: 461 ECGKVFRRNSHLARHQLIHTGEKPYKCNECGKAFRAHSNLTTHQVIHTGEKPYKCNECGK 520 Query: 196 SFRQSTHLKIHQLTHSEERPFQCCFCQKGFKIQSKLLKHKQIHTRNKAFRALLLKKRRTE 255 F Q++HL HQ H+ +P+ C C K F + S L H+ IHT K ++ K T+ Sbjct: 521 VFTQNSHLANHQRIHTGVKPYMCNECGKAFSVYSSLTTHQVIHTGEKPYKCNECGKVFTQ 580 Query: 256 SRPLPNKLNANQGGFENGEIGESEENNPLDVHSIYIVPFQCPKCEKCFESEQILNEHSCF 315 + L A G GE P++C +C K F L+ H Sbjct: 581 NSHL-----ARHRGIHTGE-----------------KPYKCNECGKVFRHNSYLSRHQ-- 616 Query: 316 AARSGKIPSRFKRSYNYKTIVKKILAKLKRARSKKLDNFQSEKKVFK--KSFLRNCDLIS 373 +G+ P Y Y K + + + K + K F +N L Sbjct: 617 RIHTGEKP------YKYNEYGKAFSEHSNLTTHQVIHTGEKPYKCNECGKVFTQNSHLAR 670 Query: 374 GEQSSEQTQRTFVGSLGK--HGTYKTIGNRKKKTLTLPFSWQNMGK--NLKGILTTENIL 429 + + GK T K +++ T P+ GK +++ LTT + Sbjct: 671 HRRVHTGGKPYQCNECGKAFSQTSKLARHQRVHTGEKPYECNQCGKAFSVRSSLTTHQAI 730 Query: 430 SIDNSVNKKDLSICGSSGEEFFNNCEVLQCGFSVPRENIRTRHKICPCDKCEKVFPSISK 489 K C G+ F N + + I T K C++C K F SK Sbjct: 731 HTGKKPYK-----CNECGKVFTQNSHLAR------HRGIHTGEKPYKCNECGKAFSQTSK 779 Query: 490 LKRHYLIHTGQR-------------------------PFGCNI 507 L RH IHTG++ P+ CN+ Sbjct: 780 LARHQRIHTGEKPYECGKPFSICSSLTTHQTIHTGGKPYKCNV 822 Score = 138 bits (347), Expect = 2e-32 Identities = 80/243 (32%), Positives = 121/243 (49%), Gaps = 28/243 (11%) Query: 25 RPYVCNICFKHFETPSKLARHYLIHTGQKPFECDVCHKTFRQLVHLERHQLTHS--LPFK 82 +PY N K F S L H +IHTG+KP++C+ C K F Q HL RH+ H+ P++ Sbjct: 623 KPYKYNEYGKAFSEHSNLTTHQVIHTGEKPYKCNECGKVFTQNSHLARHRRVHTGGKPYQ 682 Query: 83 CSICQRHFKNLKTFVKHQQLHNETYQNNVKQVRRLLEAKQEKSMYGVYNTFTTEERWALH 142 C+ C + F +HQ++H + E Q + V ++ TT + A+H Sbjct: 683 CNECGKAFSQTSKLARHQRVHTG---------EKPYECNQCGKAFSVRSSLTTHQ--AIH 731 Query: 143 PCSKSDPMYSMKRRKNIHACTICGKMFPSQSKLDRHVLIHTGQRPFKCVLCTKSFRQSTH 202 K + C CGK+F S L RH IHTG++P+KC C K+F Q++ Sbjct: 732 TGKKP------------YKCNECGKVFTQNSHLARHRGIHTGEKPYKCNECGKAFSQTSK 779 Query: 203 LKIHQLTHSEERPFQCCFCQKGFKIQSKLLKHKQIHTRNKAFRALLLKKRRTESRPLPNK 262 L HQ H+ E+P++ C K F I S L H+ IHT K ++ + K ++E +P Sbjct: 780 LARHQRIHTGEKPYE---CGKPFSICSSLTTHQTIHTGGKPYKCNVWKVLKSEFKPCKPS 836 Query: 263 LNA 265 N+ Sbjct: 837 QNS 839 Score = 122 bits (305), Expect = 1e-27 Identities = 101/389 (25%), Positives = 167/389 (42%), Gaps = 70/389 (17%) Query: 335 IVKKILAKLKRARSKKLDNFQSEKKVFK-----KSFLRNCDLISGEQS--------SEQT 381 ++K L ++ +L FQ E K+++ KSF N + +Q S++ Sbjct: 179 LIKNQLGLSLQSHLPELQLFQYEGKIYECNQVEKSFNNNSSVSPPQQMPYNVKTHISKKY 238 Query: 382 QRTFVGSL----GKHGT-----YKTIG-------------NRKKKTLTLPFSWQNMGK-- 417 + F+ SL G+ YK+ G +++ T P+ GK Sbjct: 239 LKDFISSLLLTQGQKANNWGSPYKSDGCGMVFPQNSHLASHQRSHTKEKPYKCYECGKAF 298 Query: 418 NLKGILTTENILSIDNSVNKKDLSICGSSGEEFFNNCEVLQCGFSVPRENIRTRHKICPC 477 + LTT ++ K C G+ F N ++ Q + I T K C Sbjct: 299 RTRSNLTTHQVIHTGEKRYK-----CNECGKVFSRNSQLSQ------HQKIHTGEKPYKC 347 Query: 478 DKCEKVFPSISKLKRHYLIHTGQRPFGCNICGKSFRQSAHLKRHEQTHNEKSPY-ASLCQ 536 ++C KVF S L RH IHTG++P+ CN CGK+FR + L H+ TH+ + PY + C Sbjct: 348 NECGKVFTQNSHLVRHRGIHTGEKPYKCNECGKAFRARSSLAIHQATHSGEKPYKCNECG 407 Query: 537 VEFGNFNNLSNHSGNNVNYNASQQCQAPGVQKYEVSESDQMSGVKAESQDFIPGSTGQPC 596 F ++L+NH + G + Y+ +E + GV++ + TG+ Sbjct: 408 KVFTQNSHLTNHWRIHT-----------GEKPYKCNECGKAFGVRSSLAIHLVIHTGEK- 455 Query: 597 LPNVLLESEQSNPFCSYSEHQEKNDVF-----LYRCSVCAKSFRSPSKLERHYLIHAGQK 651 + + + H ++ + Y+C+ C K+FR+ S L H +IH G+K Sbjct: 456 ----PYKCHECGKVFRRNSHLARHQLIHTGEKPYKCNECGKAFRAHSNLTTHQVIHTGEK 511 Query: 652 PFECSVCGKTFRQAPHWKRHQLTHFKERP 680 P++C+ CGK F Q H HQ H +P Sbjct: 512 PYKCNECGKVFTQNSHLANHQRIHTGVKP 540 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.321 0.133 0.413 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 28,776,568 Number of Sequences: 37866 Number of extensions: 1409539 Number of successful extensions: 65008 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 1056 Number of HSP's successfully gapped in prelim test: 30 Number of HSP's that attempted gapping in prelim test: 3433 Number of HSP's gapped (non-prelim): 21455 length of query: 691 length of database: 18,247,518 effective HSP length: 109 effective length of query: 582 effective length of database: 14,120,124 effective search space: 8217912168 effective search space used: 8217912168 T: 11 A: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.9 bits) S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.