Guide to the Human Genome
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Search of human proteins with 46094072

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|46094072 zinc finger protein 770 [Homo sapiens]
         (691 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|46094072 zinc finger protein 770 [Homo sapiens]                   1449   0.0  
gi|122937213 zinc finger protein 99 [Homo sapiens]                    253   3e-67
gi|239757212 PREDICTED: similar to hCG1773661 [Homo sapiens]          251   2e-66
gi|239751718 PREDICTED: similar to hCG1773661 [Homo sapiens]          251   2e-66
gi|239746221 PREDICTED: hypothetical protein XP_002343677 [Homo ...   251   2e-66
gi|118600985 zinc finger protein 91 [Homo sapiens]                    245   1e-64
gi|210031219 zinc finger protein 845 [Homo sapiens]                   226   4e-59
gi|172072608 zinc finger protein 624 [Homo sapiens]                   222   8e-58
gi|156627573 zinc finger protein 836 [Homo sapiens]                   222   1e-57
gi|54291708 zinc finger protein 780B [Homo sapiens]                   220   4e-57
gi|119120877 zinc finger protein 721 [Homo sapiens]                   219   5e-57
gi|150378520 zinc finger protein 594 [Homo sapiens]                   219   9e-57
gi|6005976 zinc finger protein 208 [Homo sapiens]                     218   1e-56
gi|194018469 zinc finger protein 546 [Homo sapiens]                   214   2e-55
gi|157167158 zinc finger protein 808 [Homo sapiens]                   214   3e-55
gi|40217792 zinc finger protein 585A [Homo sapiens]                   209   7e-54
gi|22749331 zinc finger protein 585A [Homo sapiens]                   209   7e-54
gi|49574543 zinc finger protein 616 [Homo sapiens]                    209   9e-54
gi|154800445 zinc finger protein 62 homolog [Homo sapiens]            207   3e-53
gi|115511042 zinc finger protein 493 isoform 1 [Homo sapiens]         207   3e-53
gi|115511044 zinc finger protein 493 isoform 3 [Homo sapiens]         207   3e-53
gi|211057416 zinc finger protein 841 [Homo sapiens]                   206   8e-53
gi|47271464 zinc finger protein 607 [Homo sapiens]                    206   8e-53
gi|222418585 zinc finger protein 814 [Homo sapiens]                   203   5e-52
gi|62243640 zinc finger protein 107 [Homo sapiens]                    202   6e-52
gi|7706775 zinc finger protein 107 [Homo sapiens]                     202   6e-52
gi|11386193 zinc finger protein 197 isoform 1 [Homo sapiens]          202   6e-52
gi|55769537 zinc finger protein 658 [Homo sapiens]                    201   2e-51
gi|68303809 zinc finger protein 43 [Homo sapiens]                     199   7e-51
gi|14211907 zinc finger protein 347 [Homo sapiens]                    199   7e-51

>gi|46094072 zinc finger protein 770 [Homo sapiens]
          Length = 691

 Score = 1449 bits (3750), Expect = 0.0
 Identities = 691/691 (100%), Positives = 691/691 (100%)

Query: 1   MMAENNLKMLKIQQCVVANKLPRNRPYVCNICFKHFETPSKLARHYLIHTGQKPFECDVC 60
           MMAENNLKMLKIQQCVVANKLPRNRPYVCNICFKHFETPSKLARHYLIHTGQKPFECDVC
Sbjct: 1   MMAENNLKMLKIQQCVVANKLPRNRPYVCNICFKHFETPSKLARHYLIHTGQKPFECDVC 60

Query: 61  HKTFRQLVHLERHQLTHSLPFKCSICQRHFKNLKTFVKHQQLHNETYQNNVKQVRRLLEA 120
           HKTFRQLVHLERHQLTHSLPFKCSICQRHFKNLKTFVKHQQLHNETYQNNVKQVRRLLEA
Sbjct: 61  HKTFRQLVHLERHQLTHSLPFKCSICQRHFKNLKTFVKHQQLHNETYQNNVKQVRRLLEA 120

Query: 121 KQEKSMYGVYNTFTTEERWALHPCSKSDPMYSMKRRKNIHACTICGKMFPSQSKLDRHVL 180
           KQEKSMYGVYNTFTTEERWALHPCSKSDPMYSMKRRKNIHACTICGKMFPSQSKLDRHVL
Sbjct: 121 KQEKSMYGVYNTFTTEERWALHPCSKSDPMYSMKRRKNIHACTICGKMFPSQSKLDRHVL 180

Query: 181 IHTGQRPFKCVLCTKSFRQSTHLKIHQLTHSEERPFQCCFCQKGFKIQSKLLKHKQIHTR 240
           IHTGQRPFKCVLCTKSFRQSTHLKIHQLTHSEERPFQCCFCQKGFKIQSKLLKHKQIHTR
Sbjct: 181 IHTGQRPFKCVLCTKSFRQSTHLKIHQLTHSEERPFQCCFCQKGFKIQSKLLKHKQIHTR 240

Query: 241 NKAFRALLLKKRRTESRPLPNKLNANQGGFENGEIGESEENNPLDVHSIYIVPFQCPKCE 300
           NKAFRALLLKKRRTESRPLPNKLNANQGGFENGEIGESEENNPLDVHSIYIVPFQCPKCE
Sbjct: 241 NKAFRALLLKKRRTESRPLPNKLNANQGGFENGEIGESEENNPLDVHSIYIVPFQCPKCE 300

Query: 301 KCFESEQILNEHSCFAARSGKIPSRFKRSYNYKTIVKKILAKLKRARSKKLDNFQSEKKV 360
           KCFESEQILNEHSCFAARSGKIPSRFKRSYNYKTIVKKILAKLKRARSKKLDNFQSEKKV
Sbjct: 301 KCFESEQILNEHSCFAARSGKIPSRFKRSYNYKTIVKKILAKLKRARSKKLDNFQSEKKV 360

Query: 361 FKKSFLRNCDLISGEQSSEQTQRTFVGSLGKHGTYKTIGNRKKKTLTLPFSWQNMGKNLK 420
           FKKSFLRNCDLISGEQSSEQTQRTFVGSLGKHGTYKTIGNRKKKTLTLPFSWQNMGKNLK
Sbjct: 361 FKKSFLRNCDLISGEQSSEQTQRTFVGSLGKHGTYKTIGNRKKKTLTLPFSWQNMGKNLK 420

Query: 421 GILTTENILSIDNSVNKKDLSICGSSGEEFFNNCEVLQCGFSVPRENIRTRHKICPCDKC 480
           GILTTENILSIDNSVNKKDLSICGSSGEEFFNNCEVLQCGFSVPRENIRTRHKICPCDKC
Sbjct: 421 GILTTENILSIDNSVNKKDLSICGSSGEEFFNNCEVLQCGFSVPRENIRTRHKICPCDKC 480

Query: 481 EKVFPSISKLKRHYLIHTGQRPFGCNICGKSFRQSAHLKRHEQTHNEKSPYASLCQVEFG 540
           EKVFPSISKLKRHYLIHTGQRPFGCNICGKSFRQSAHLKRHEQTHNEKSPYASLCQVEFG
Sbjct: 481 EKVFPSISKLKRHYLIHTGQRPFGCNICGKSFRQSAHLKRHEQTHNEKSPYASLCQVEFG 540

Query: 541 NFNNLSNHSGNNVNYNASQQCQAPGVQKYEVSESDQMSGVKAESQDFIPGSTGQPCLPNV 600
           NFNNLSNHSGNNVNYNASQQCQAPGVQKYEVSESDQMSGVKAESQDFIPGSTGQPCLPNV
Sbjct: 541 NFNNLSNHSGNNVNYNASQQCQAPGVQKYEVSESDQMSGVKAESQDFIPGSTGQPCLPNV 600

Query: 601 LLESEQSNPFCSYSEHQEKNDVFLYRCSVCAKSFRSPSKLERHYLIHAGQKPFECSVCGK 660
           LLESEQSNPFCSYSEHQEKNDVFLYRCSVCAKSFRSPSKLERHYLIHAGQKPFECSVCGK
Sbjct: 601 LLESEQSNPFCSYSEHQEKNDVFLYRCSVCAKSFRSPSKLERHYLIHAGQKPFECSVCGK 660

Query: 661 TFRQAPHWKRHQLTHFKERPQGKVVALDSVM 691
           TFRQAPHWKRHQLTHFKERPQGKVVALDSVM
Sbjct: 661 TFRQAPHWKRHQLTHFKERPQGKVVALDSVM 691


>gi|122937213 zinc finger protein 99 [Homo sapiens]
          Length = 1036

 Score =  253 bits (647), Expect = 3e-67
 Identities = 193/712 (27%), Positives = 311/712 (43%), Gaps = 88/712 (12%)

Query: 3   AENNLKMLKIQQCVVANKLPRNRPYVCNICFKHFETPSKLARHYLIHTGQKPFECDVCHK 62
           A +NL  L+  + +   +    +PY C  C K F+  SKL  H +IHT +KP +C+ C K
Sbjct: 286 AFSNLSALRKHEIIHTGQ----KPYKCEECGKAFKWSSKLTVHKVIHTAEKPCKCEECGK 341

Query: 63  TFRQLVHLERHQLTHS--LPFKCSICQRHFKNLKTFVKHQQLHNETYQNNVKQVRRLLEA 120
            F++   L +H++ H+   P+KC  C + F N     KH+ +H        ++  +  + 
Sbjct: 342 AFKRFSALRKHKIIHTGKQPYKCEECSKAFSNFSALRKHEIIHTGEKPYKCEECGKAFKW 401

Query: 121 KQEKSMYGVYNTFTTEERWALHPCSKSDPMYS-MKRRKNIHA------CTICGKMFPSQS 173
             + +++ V +    E+      C K+   +S +++ K IH       C  CGK F + S
Sbjct: 402 SSKLTVHKVIHM--EEKPCKCEECGKAFKHFSALRKHKIIHTGKKPYKCEECGKAFNNSS 459

Query: 174 KLDRHVLIHTGQRPFKCVLCTKSFRQSTHLKIHQLTHSEERPFQCCFCQKGFKIQSKLLK 233
            L +H +IHTG++P+KC  C K+F+QS+HL  H+  H+ E+P++C  C K F   S L K
Sbjct: 460 TLMKHKIIHTGKKPYKCEECGKAFKQSSHLTRHKAIHTGEKPYKCEECGKAFNHFSALRK 519

Query: 234 HKQIHTRNKAFRALLLKKRRTESRPLPNKLNANQGGFENGEIGESEENNPLDVHSIYIVP 293
           H+ IHT  K ++     K  ++S  L              EI  + E            P
Sbjct: 520 HQIIHTGKKPYKCEECGKAFSQSSTL-----------RKHEIIHTGEK-----------P 557

Query: 294 FQCPKCEKCFESEQILNEHSCFAARSGKIP-SRFKRSYNYKTIVKKILAKLKRARSKKLD 352
           ++C +C K F+    L  H                +++N+ + ++K   K+     K   
Sbjct: 558 YKCEECGKAFKWSSHLTRHKVIHTEEKPYKCEECGKAFNHFSALRK--HKIIHTGKKPYK 615

Query: 353 NFQSEKKVFKKSFLRNCDLI-SGEQ--SSEQTQRTFVGSLGKHGTYKTIGNRKKKTLTLP 409
             +  K   + S LR  ++I +GE+    E+  + F  S  K   +K I   +K     P
Sbjct: 616 CEECGKAFSQSSTLRKHEIIHTGEKPYKCEECGKAFKWS-SKLTVHKVIHTAEK-----P 669

Query: 410 FSWQNMGKNLKGILTTENILSIDNSVNKKDLSICGSSGEEFFNNCEVL------------ 457
              +  GK  K          I           CG +    FNN   L            
Sbjct: 670 CKCEECGKAFKHFSALRKHKIIHTGKKPYKCEECGKA----FNNSSTLRKHEIIHTGEKS 725

Query: 458 ----QCGFSVPRENIRTRHKICPCDKCEKVFPSISKLKRHYLIHTGQRPFGCNICGKSFR 513
               +C      E I T  K   C++C K F + S L++H +I+TG++P+ C  CGK+F+
Sbjct: 726 YKCEECALR-KHEIIHTGKKPYKCEECGKAFNNSSTLRKHKIIYTGKKPYKCEECGKAFK 784

Query: 514 QSAHLKRHEQTHNEKSPY-ASLCQVEFGNFNNLSNHSGNNVNYNASQQCQAPGVQKYEVS 572
           QS+HL RH+  H  + PY    C   F N + L  H   +     S +C+  G      S
Sbjct: 785 QSSHLTRHKAVHTGEKPYKCGECGKAFNNSSTLKKHKLIHTR-EKSYKCEECGKAFSNFS 843

Query: 573 ESDQMSGVKAESQDFIPGSTGQPCLPNVLLESEQSNPFCSYSEHQEKNDVFL----YRCS 628
              +   +           TG+   P    E E    F + S   +   +      Y+C 
Sbjct: 844 ALRKHKIIH----------TGEK--PYKCEECECGKAFNNSSTLMKHKIIHTGEKPYKCE 891

Query: 629 VCAKSFRSPSKLERHYLIHAGQKPFECSVCGKTFRQAPHWKRHQLTHFKERP 680
            C K F + S L +H +IH G+KP++C  CGK F+Q+ H  +H+  H  E+P
Sbjct: 892 ECGKGFNNFSTLMKHKIIHTGEKPYKCEECGKAFKQSSHLTKHKSIHTGEKP 943



 Score =  249 bits (635), Expect = 8e-66
 Identities = 187/700 (26%), Positives = 308/700 (44%), Gaps = 95/700 (13%)

Query: 25   RPYVCNICFKHFETPSKLARHYLIHTGQKPFECDVCHKTFRQLVHLERHQLTHS--LPFK 82
            +PY C  C K F+  SKL  H +IH  +KP +C+ C K F+    L +H++ H+   P+K
Sbjct: 388  KPYKCEECGKAFKWSSKLTVHKVIHMEEKPCKCEECGKAFKHFSALRKHKIIHTGKKPYK 447

Query: 83   CSICQRHFKNLKTFVKHQQLHNETYQNNVKQVRRLLEAKQEKSMYGVYNTFTTEERWALH 142
            C  C + F N  T +KH+ +H        ++  +  +     + +   +T   E+ +   
Sbjct: 448  CEECGKAFNNSSTLMKHKIIHTGKKPYKCEECGKAFKQSSHLTRHKAIHT--GEKPYKCE 505

Query: 143  PCSKSDPMYSMKRRKNI-------HACTICGKMFPSQSKLDRHVLIHTGQRPFKCVLCTK 195
             C K+   +S  R+  I       + C  CGK F   S L +H +IHTG++P+KC  C K
Sbjct: 506  ECGKAFNHFSALRKHQIIHTGKKPYKCEECGKAFSQSSTLRKHEIIHTGEKPYKCEECGK 565

Query: 196  SFRQSTHLKIHQLTHSEERPFQCCFCQKGFKIQSKLLKHKQIHTRNKAFRALLLKKRRTE 255
            +F+ S+HL  H++ H+EE+P++C  C K F   S L KHK IHT  K ++     K  ++
Sbjct: 566  AFKWSSHLTRHKVIHTEEKPYKCEECGKAFNHFSALRKHKIIHTGKKPYKCEECGKAFSQ 625

Query: 256  SRPLPNK--LNANQGGFENGEIGESEE-NNPLDVHSIYIV---PFQCPKCEKCFESEQIL 309
            S  L     ++  +  ++  E G++ + ++ L VH +      P +C +C K F+    L
Sbjct: 626  SSTLRKHEIIHTGEKPYKCEECGKAFKWSSKLTVHKVIHTAEKPCKCEECGKAFKHFSAL 685

Query: 310  NEHSCFAARSGKIPSRFK---RSYNYKTIVKKILA--------KLKRARSKKLDNFQSEK 358
             +H      +GK P + +   +++N  + ++K           K +    +K +   + K
Sbjct: 686  RKHKII--HTGKKPYKCEECGKAFNNSSTLRKHEIIHTGEKSYKCEECALRKHEIIHTGK 743

Query: 359  KVFKKSFLRNCDLISGEQSSEQTQRTFVGSLGKHGTYKTIGNRKKKTLTLPFSWQNMGKN 418
            K +K      C+      ++  T R       KH   K I   KK     P+  +  GK 
Sbjct: 744  KPYK------CEECGKAFNNSSTLR-------KH---KIIYTGKK-----PYKCEECGKA 782

Query: 419  LK--GILTTENILSIDNSVNKKDLSICGSSGEEFFNNCEVLQCGFSVPRENIRTRHKICP 476
             K    LT    +       K     CG  G+ F NN   L+       + I TR K   
Sbjct: 783  FKQSSHLTRHKAVHTGEKPYK-----CGECGKAF-NNSSTLK-----KHKLIHTREKSYK 831

Query: 477  CDKCEKVFPSISKLKRHYLIHTGQRPFGCNIC--GKSFRQSAHLKRHEQTHNEKSPY-AS 533
            C++C K F + S L++H +IHTG++P+ C  C  GK+F  S+ L +H+  H  + PY   
Sbjct: 832  CEECGKAFSNFSALRKHKIIHTGEKPYKCEECECGKAFNNSSTLMKHKIIHTGEKPYKCE 891

Query: 534  LCQVEFGNFNNLSNHSGNNVNYNASQQCQAPGVQKYEVSESDQMSGVKAESQDFIPGSTG 593
             C   F NF+ L  H   +       +C+       E  ++ + S    + +    G   
Sbjct: 892  ECGKGFNNFSTLMKHKIIHTG-EKPYKCE-------ECGKAFKQSSHLTKHKSIHTGEKP 943

Query: 594  QPCLPNVLLESEQSNPFCSYSEHQEKNDVFL-------------YRCSVCAKSFRSPSKL 640
              C        E+   F  +S   +   +               Y+C  C K+F   S L
Sbjct: 944  YKC-------EERGKAFSHFSRLTKHRIIHTGKKPYKCEECEKPYKCEECGKAFNQSSHL 996

Query: 641  ERHYLIHAGQKPFECSVCGKTFRQAPHWKRHQLTHFKERP 680
             +H  IH G K ++C  CGK F       +H++ H  E+P
Sbjct: 997  TQHKTIHTGGKTYKCEECGKAFNHLSALTKHKIIHTGEKP 1036



 Score =  239 bits (609), Expect = 8e-63
 Identities = 194/709 (27%), Positives = 328/709 (46%), Gaps = 99/709 (13%)

Query: 11  KIQQCVVANKLPRNRPYVCNICFKHFETPSKLARHYLIHTGQKPFECDVCHKTFRQLVHL 70
           K+ QC    +    + + CN   K F   S   R+ +IHTG+KP++C+ C K F+Q  HL
Sbjct: 153 KLNQCWTTTQ---GKIFQCNKYVKVFHKYSNSNRYKIIHTGKKPYKCEECGKAFKQSSHL 209

Query: 71  ERHQLTHS--LPFKCSICQRHFKNLKTFVKHQQLHNETYQNNVKQVRRLLEAKQEKSMYG 128
            RH+  H+   P+KC  C + F +     KHQ +H        ++  +   A  + S   
Sbjct: 210 TRHKAIHTGEKPYKCEECGKAFNHFSALRKHQIIHTGKKPYKCEECGK---AFSQSSTLR 266

Query: 129 VYNTFTTEERWALHPCSKSDPMYSMKRRKNIHACTICGKMFPSQSKLDRHVLIHTGQRPF 188
            +    TEE+    P    +                CGK F + S L +H +IHTGQ+P+
Sbjct: 267 KHEIIHTEEK----PYKYEE----------------CGKAFSNLSALRKHEIIHTGQKPY 306

Query: 189 KCVLCTKSFRQSTHLKIHQLTHSEERPFQCCFCQKGFKIQSKLLKHKQIHTRNKAFRALL 248
           KC  C K+F+ S+ L +H++ H+ E+P +C  C K FK  S L KHK IHT  + ++   
Sbjct: 307 KCEECGKAFKWSSKLTVHKVIHTAEKPCKCEECGKAFKRFSALRKHKIIHTGKQPYKCEE 366

Query: 249 LKKRRTESRPLPNK--LNANQGGFENGEIGES-EENNPLDVHSIYIV---PFQCPKCEKC 302
             K  +    L     ++  +  ++  E G++ + ++ L VH +  +   P +C +C K 
Sbjct: 367 CSKAFSNFSALRKHEIIHTGEKPYKCEECGKAFKWSSKLTVHKVIHMEEKPCKCEECGKA 426

Query: 303 FESEQILNEHSCFAARSGKIPSRF----KRSYNYKTIVK-KILAKLKRARSKKLDNFQSE 357
           F+    L +H      +GK P +     K   N  T++K KI+        KK    +  
Sbjct: 427 FKHFSALRKHKII--HTGKKPYKCEECGKAFNNSSTLMKHKII-----HTGKKPYKCEEC 479

Query: 358 KKVFKKS--FLRNCDLISGEQ--SSEQTQRTF--VGSLGKHGTYKTIGNRKKKTLTLPFS 411
            K FK+S    R+  + +GE+    E+  + F    +L KH   + I   KK     P+ 
Sbjct: 480 GKAFKQSSHLTRHKAIHTGEKPYKCEECGKAFNHFSALRKH---QIIHTGKK-----PYK 531

Query: 412 WQNMGKNLKGILTTENILSIDNSVNKKDLSICGSSGEEFFNNCEVLQCGFSVPRENIRTR 471
            +  GK            S  +++ K ++     +GE+ +  CE  +CG +    +  TR
Sbjct: 532 CEECGK----------AFSQSSTLRKHEII---HTGEKPY-KCE--ECGKAFKWSSHLTR 575

Query: 472 HKIC-------PCDKCEKVFPSISKLKRHYLIHTGQRPFGCNICGKSFRQSAHLKRHEQT 524
           HK+         C++C K F   S L++H +IHTG++P+ C  CGK+F QS+ L++HE  
Sbjct: 576 HKVIHTEEKPYKCEECGKAFNHFSALRKHKIIHTGKKPYKCEECGKAFSQSSTLRKHEII 635

Query: 525 HNEKSPYASLCQVEFGNFNNLSNHSGNNVNYNASQQCQA----------PGVQKYEVSES 574
           H  + PY   C+     F   S  + + V + A + C+             ++K+++  +
Sbjct: 636 HTGEKPYK--CEECGKAFKWSSKLTVHKVIHTAEKPCKCEECGKAFKHFSALRKHKIIHT 693

Query: 575 DQMSGVKAESQDFIPGSTGQPCLPNVLLESEQSNPF--CSYSEHQ-EKNDVFLYRCSVCA 631
            +    K E       ++       ++   E+S     C+  +H+        Y+C  C 
Sbjct: 694 GK-KPYKCEECGKAFNNSSTLRKHEIIHTGEKSYKCEECALRKHEIIHTGKKPYKCEECG 752

Query: 632 KSFRSPSKLERHYLIHAGQKPFECSVCGKTFRQAPHWKRHQLTHFKERP 680
           K+F + S L +H +I+ G+KP++C  CGK F+Q+ H  RH+  H  E+P
Sbjct: 753 KAFNNSSTLRKHKIIYTGKKPYKCEECGKAFKQSSHLTRHKAVHTGEKP 801



 Score =  191 bits (484), Expect = 3e-48
 Identities = 156/596 (26%), Positives = 250/596 (41%), Gaps = 117/596 (19%)

Query: 112 KQVRRLLEAKQEKSMYGVYNTFTTEERWALHPCSKSDPMY----SMKRRKNIHA------ 161
           K    + E K  +  Y   N   T  +  +  C+K   ++    +  R K IH       
Sbjct: 136 KDCESVNEGKMHEEAYNKLNQCWTTTQGKIFQCNKYVKVFHKYSNSNRYKIIHTGKKPYK 195

Query: 162 CTICGKMFPSQSKLDRHVLIHTGQRPFKCVLCTKSFRQSTHLKIHQLTHSEERPFQCCFC 221
           C  CGK F   S L RH  IHTG++P+KC  C K+F   + L+ HQ+ H+ ++P++C  C
Sbjct: 196 CEECGKAFKQSSHLTRHKAIHTGEKPYKCEECGKAFNHFSALRKHQIIHTGKKPYKCEEC 255

Query: 222 QKGFKIQSKLLKHKQIHTRNKAFRALLLKKRRTESRPLPNK--LNANQGGFENGEIGESE 279
            K F   S L KH+ IHT  K ++     K  +    L     ++  Q  ++  E G++ 
Sbjct: 256 GKAFSQSSTLRKHEIIHTEEKPYKYEECGKAFSNLSALRKHEIIHTGQKPYKCEECGKAF 315

Query: 280 E-NNPLDVHSIYIV---PFQCPKCEKCFESEQILNEHSCFAARSGKIPSRFKRSYNYKTI 335
           + ++ L VH +      P +C +C K F+    L +H      +GK P + +        
Sbjct: 316 KWSSKLTVHKVIHTAEKPCKCEECGKAFKRFSALRKHKII--HTGKQPYKCEEC------ 367

Query: 336 VKKILAKLKRARSKKLDNFQSEKKVFKKSFLRNCDLI-SGEQSSEQTQRTFVGSLGKHGT 394
                       SK   NF         S LR  ++I +GE+                  
Sbjct: 368 ------------SKAFSNF---------SALRKHEIIHTGEK------------------ 388

Query: 395 YKTIGNRKKKTLTLPFSWQNMGKNLK--GILTTENILSIDNSVNKKDLSICGSSGEEFFN 452
                         P+  +  GK  K    LT   ++ ++    K     C   G+ F +
Sbjct: 389 --------------PYKCEECGKAFKWSSKLTVHKVIHMEEKPCK-----CEECGKAFKH 429

Query: 453 NCEVLQCGFSVPREN--IRTRHKICPCDKCEKVFPSISKLKRHYLIHTGQRPFGCNICGK 510
                   FS  R++  I T  K   C++C K F + S L +H +IHTG++P+ C  CGK
Sbjct: 430 --------FSALRKHKIIHTGKKPYKCEECGKAFNNSSTLMKHKIIHTGKKPYKCEECGK 481

Query: 511 SFRQSAHLKRHEQTHNEKSPY-ASLCQVEFGNFNNLSNHSGNNVNYNASQQCQAPGVQKY 569
           +F+QS+HL RH+  H  + PY    C   F +F+ L  H           Q    G + Y
Sbjct: 482 AFKQSSHLTRHKAIHTGEKPYKCEECGKAFNHFSALRKH-----------QIIHTGKKPY 530

Query: 570 EVSESDQMSGVKAESQDFIPGSTGQPCLPNVLLESEQSNPFCSYSEHQEKNDVFL----- 624
           +  E  +     +  +      TG+        + E+      +S H  ++ V       
Sbjct: 531 KCEECGKAFSQSSTLRKHEIIHTGEKPY-----KCEECGKAFKWSSHLTRHKVIHTEEKP 585

Query: 625 YRCSVCAKSFRSPSKLERHYLIHAGQKPFECSVCGKTFRQAPHWKRHQLTHFKERP 680
           Y+C  C K+F   S L +H +IH G+KP++C  CGK F Q+   ++H++ H  E+P
Sbjct: 586 YKCEECGKAFNHFSALRKHKIIHTGKKPYKCEECGKAFSQSSTLRKHEIIHTGEKP 641



 Score =  125 bits (314), Expect = 1e-28
 Identities = 85/286 (29%), Positives = 129/286 (45%), Gaps = 50/286 (17%)

Query: 3    AENNLKMLKIQQCVVANKLPRNRPYVCNICFKHFETPSKLARHYLIHTGQKPFECDVCHK 62
            A NN   L+  + +   K    +PY C  C K F+  S L RH  +HTG+KP++C  C K
Sbjct: 754  AFNNSSTLRKHKIIYTGK----KPYKCEECGKAFKQSSHLTRHKAVHTGEKPYKCGECGK 809

Query: 63   TFRQLVHLERHQLTHSLP--FKCSICQRHFKNLKTFVKHQQLHN-------------ETY 107
             F     L++H+L H+    +KC  C + F N     KH+ +H              + +
Sbjct: 810  AFNNSSTLKKHKLIHTREKSYKCEECGKAFSNFSALRKHKIIHTGEKPYKCEECECGKAF 869

Query: 108  QNNVKQVRRLLEAKQEKSMYGV-----YNTFTT----------EERWALHPCSKSDPMYS 152
             N+   ++  +    EK          +N F+T          E+ +    C K+    S
Sbjct: 870  NNSSTLMKHKIIHTGEKPYKCEECGKGFNNFSTLMKHKIIHTGEKPYKCEECGKAFKQSS 929

Query: 153  -MKRRKNIHA------CTICGKMFPSQSKLDRHVLIHTGQRPFKCVLCTK---------S 196
             + + K+IH       C   GK F   S+L +H +IHTG++P+KC  C K         +
Sbjct: 930  HLTKHKSIHTGEKPYKCEERGKAFSHFSRLTKHRIIHTGKKPYKCEECEKPYKCEECGKA 989

Query: 197  FRQSTHLKIHQLTHSEERPFQCCFCQKGFKIQSKLLKHKQIHTRNK 242
            F QS+HL  H+  H+  + ++C  C K F   S L KHK IHT  K
Sbjct: 990  FNQSSHLTQHKTIHTGGKTYKCEECGKAFNHLSALTKHKIIHTGEK 1035



 Score =  105 bits (262), Expect = 1e-22
 Identities = 67/234 (28%), Positives = 106/234 (45%), Gaps = 28/234 (11%)

Query: 3    AENNLKMLKIQQCVVANKLPRNRPYVCNICFKHFETPSKLARHYLIHTGQKPFECDVCH- 61
            A NN   LK  + +      R + Y C  C K F   S L +H +IHTG+KP++C+ C  
Sbjct: 810  AFNNSSTLKKHKLIHT----REKSYKCEECGKAFSNFSALRKHKIIHTGEKPYKCEECEC 865

Query: 62   -KTFRQLVHLERHQLTHS--LPFKCSICQRHFKNLKTFVKHQQLHNETYQNNVKQVRRLL 118
             K F     L +H++ H+   P+KC  C + F N  T +KH+ +H        ++  +  
Sbjct: 866  GKAFNNSSTLMKHKIIHTGEKPYKCEECGKGFNNFSTLMKHKIIHTGEKPYKCEECGKAF 925

Query: 119  EAK----QEKSMYGVYNTFTTEERWA-------------LHPCSKSDPMYSMKRRKNIHA 161
            +      + KS++     +  EER               +H   K    Y  +  +  + 
Sbjct: 926  KQSSHLTKHKSIHTGEKPYKCEERGKAFSHFSRLTKHRIIHTGKKP---YKCEECEKPYK 982

Query: 162  CTICGKMFPSQSKLDRHVLIHTGQRPFKCVLCTKSFRQSTHLKIHQLTHSEERP 215
            C  CGK F   S L +H  IHTG + +KC  C K+F   + L  H++ H+ E+P
Sbjct: 983  CEECGKAFNQSSHLTQHKTIHTGGKTYKCEECGKAFNHLSALTKHKIIHTGEKP 1036


>gi|239757212 PREDICTED: similar to hCG1773661 [Homo sapiens]
          Length = 1119

 Score =  251 bits (640), Expect = 2e-66
 Identities = 190/687 (27%), Positives = 310/687 (45%), Gaps = 100/687 (14%)

Query: 25  RPYVCNICFKHFETPSKLARHYLIHTGQKPFECDVCHKTFRQLVHLERHQLTHS--LPFK 82
           +PY C  C K F   S L RH  IHTG+KP++C+ C K F     L RH++ H+   P+K
Sbjct: 325 KPYKCEECGKAFRQSSHLTRHKAIHTGEKPYKCEECGKAFNHFSDLRRHKIIHTGKKPYK 384

Query: 83  CSICQRHFKNLKTFVKHQQLHNETYQNNVKQVRRLLEAKQEKSMYGVYNTFTTEERWALH 142
           C  C + F    T   HQ +H        ++  +  +   + +++ V +T   E+     
Sbjct: 385 CEECGKAFSQSSTLRNHQIIHTGEKPYKCEECGKAFKWSSKLTVHKVIHT--GEKPCKCE 442

Query: 143 PCSKSDPMYSMKR-------RKNIHACTICGKMFPSQSKLDRHVLIHTGQRPFKCVLCTK 195
            C K+   +S  R       R+ ++ C  CGK F + S L +H +IHTG++P+KC  C K
Sbjct: 443 ECGKAFKHFSALRKHKVIHTREKLYKCEECGKAFNNSSILAKHKIIHTGKKPYKCEECGK 502

Query: 196 SFRQSTHLKIHQLTHSEERPFQCCFCQKGFKIQSKLLKHKQIHTRNKAFRALLLKKRRTE 255
           +FRQS+HL  H+  H+ E+P++C  C K F   S L +HK IHT  K ++     K  + 
Sbjct: 503 AFRQSSHLTRHKAIHTGEKPYKCEECGKAFSHFSALRRHKIIHTGKKPYKCEECGKAFSH 562

Query: 256 SRPLPNK--LNANQGGFENGEIGESEE-NNPLDVHSIYIV---PFQCPKCEKCFESEQIL 309
              L     ++  +  ++  E G++ + ++ L VH +      P +C +C K F+    L
Sbjct: 563 FSALRRHKIIHTGEKPYKCEECGKAFKWSSKLTVHKVIHTAEKPCKCEECGKSFKHFSAL 622

Query: 310 NEHSCFAARSG--KIPSRFKRSYNYKTIVKKILAKLKRARSKKLDNFQSEKKVFKKSFLR 367
            +H     R    K     K   ++  ++K  +        +K    +   K FK S   
Sbjct: 623 RKHKVIHTREKLYKCEECVKAFNSFSALMKHKVIHT----GEKPYKCEECGKAFKWSSKL 678

Query: 368 NCDLI--SGEQ--SSEQTQRTF--VGSLGKHGTYKTIGNRKKKTLTLPFSWQNMGKNLKG 421
               +  +GE+    E+  + F    +L KH   K I   KK     P+  +  GK    
Sbjct: 679 TVHKVIHTGEKPCKCEECGKAFKHFSALRKH---KVIHTGKK-----PYKCEECGK---- 726

Query: 422 ILTTENILSIDNSVNKKDLSICGSSGEEFFNNCEVLQCGFSVPRENIRTRHKI------- 474
                   S  +S+ K ++     SGE+ +  CE  +CG +    +  T HK+       
Sbjct: 727 ------AFSQSSSLRKHEII---HSGEKPYK-CE--ECGKAFKWLSKLTVHKVIHTAEKP 774

Query: 475 CPCDKCEKVFPSISKLKRHYLIHTGQRPFGCNICGKSFRQSAHLKRHEQTHNEKSPY-AS 533
           C C++C K F   S L++H +IHTG++P+ C  CGK+F  S+ L +H+  H  K PY  +
Sbjct: 775 CKCEECGKAFKHFSALRKHKIIHTGKKPYKCEECGKAFNDSSTLMKHKIIHTGKKPYKCA 834

Query: 534 LCQVEFGNFNNLSNHSGNNVNYNASQQCQAPGVQKYEVSESDQMSGVKAESQDFIPGSTG 593
            C   F   ++L+ H   +            G + Y+  E           +DF   ST 
Sbjct: 835 ECGKAFKQSSHLTRHKAIHT-----------GEKPYKCEEC---------GKDFNNSST- 873

Query: 594 QPCLPNVLLESEQSNPFCSYSEHQEKNDVFLYRCSVCAKSFRSPSKLERHYLIHAGQKPF 653
                + L+ + +                 LY+C  C K+F + S L +H +IH G+KP+
Sbjct: 874 --LKKHKLIHTREK----------------LYKCEECVKAFNNFSALMKHKIIHTGEKPY 915

Query: 654 ECSVCGKTFRQAPHWKRHQLTHFKERP 680
           +C  CGK F+ +     H++ H  E+P
Sbjct: 916 KCEECGKAFKWSSKLTEHKVIHTGEKP 942



 Score =  249 bits (635), Expect = 8e-66
 Identities = 196/711 (27%), Positives = 307/711 (43%), Gaps = 92/711 (12%)

Query: 25   RPYVCNICFKHFETPSKLARHYLIHTGQKPFECDVCHKTFRQLVHLERHQLTHSLP--FK 82
            +PY C  C K F+  SKL  H +IHTG+KP +C+ C K F+    L +H++ H+    +K
Sbjct: 409  KPYKCEECGKAFKWSSKLTVHKVIHTGEKPCKCEECGKAFKHFSALRKHKVIHTREKLYK 468

Query: 83   CSICQRHFKNLKTFVKHQQLHNETYQNNVKQVRRLLEAKQEKSMYGVYNTFTTEERWALH 142
            C  C + F N     KH+ +H        ++  +        + +   +T   E+ +   
Sbjct: 469  CEECGKAFNNSSILAKHKIIHTGKKPYKCEECGKAFRQSSHLTRHKAIHT--GEKPYKCE 526

Query: 143  PCSKSDPMYS-MKRRKNIHA------CTICGKMFPSQSKLDRHVLIHTGQRPFKCVLCTK 195
             C K+   +S ++R K IH       C  CGK F   S L RH +IHTG++P+KC  C K
Sbjct: 527  ECGKAFSHFSALRRHKIIHTGKKPYKCEECGKAFSHFSALRRHKIIHTGEKPYKCEECGK 586

Query: 196  SFRQSTHLKIHQLTHSEERPFQCCFCQKGFKIQSKLLKHKQIHTRNKAFRAL-LLKKRRT 254
            +F+ S+ L +H++ H+ E+P +C  C K FK  S L KHK IHTR K ++    +K   +
Sbjct: 587  AFKWSSKLTVHKVIHTAEKPCKCEECGKSFKHFSALRKHKVIHTREKLYKCEECVKAFNS 646

Query: 255  ESRPLPNK-LNANQGGFENGEIGESEE-NNPLDVHSIYIV-------------------- 292
             S  + +K ++  +  ++  E G++ + ++ L VH +                       
Sbjct: 647  FSALMKHKVIHTGEKPYKCEECGKAFKWSSKLTVHKVIHTGEKPCKCEECGKAFKHFSAL 706

Query: 293  -----------PFQCPKCEKCFESEQILNEHSCFAARSGKIPSRFKRSYN-YKTIVKKIL 340
                       P++C +C K F     L +H      SG+ P + +     +K + K  +
Sbjct: 707  RKHKVIHTGKKPYKCEECGKAFSQSSSLRKHEII--HSGEKPYKCEECGKAFKWLSKLTV 764

Query: 341  AKLKRARSKKLDNFQSEKKVFKKSFLRNCDLI-SGEQ--SSEQTQRTFVGS--LGKHGTY 395
             K+     K     +  K     S LR   +I +G++    E+  + F  S  L KH   
Sbjct: 765  HKVIHTAEKPCKCEECGKAFKHFSALRKHKIIHTGKKPYKCEECGKAFNDSSTLMKH--- 821

Query: 396  KTIGNRKKKTLTLPFSWQNMGKNLKGILTTENILSIDNSVNKKDLSICGSSGEEFFNNCE 455
            K I   KK     P+     GK  K         +I           CG      FNN  
Sbjct: 822  KIIHTGKK-----PYKCAECGKAFKQSSHLTRHKAIHTGEKPYKCEECGKD----FNNSS 872

Query: 456  VLQCGFSVPRENIRTRHKICPCDKCEKVFPSISKLKRHYLIHTGQRPFGCNICGKSFRQS 515
             L+       + I TR K+  C++C K F + S L +H +IHTG++P+ C  CGK+F+ S
Sbjct: 873  TLK-----KHKLIHTREKLYKCEECVKAFNNFSALMKHKIIHTGEKPYKCEECGKAFKWS 927

Query: 516  AHLKRHEQTH-NEKSPYASLCQVEFGNFNNLSNHSGNNVNYNASQQCQAPGVQKYEVSES 574
            + L  H+  H  EK      C   F +F+ L  H   +       QC        E  ++
Sbjct: 928  SKLTEHKVIHTGEKPCKCEECDKAFKHFSALRKHKVIHTG-KKPYQCD-------ECGKA 979

Query: 575  DQMSGVKAESQDFIPGSTGQPCLPNVLLESEQSNPFCSYSEHQEKNDVF-----LYRCSV 629
               S    + +    G     C        E+     S S    K+ +       Y+C  
Sbjct: 980  FNNSSTLTKHKIIHTGEKPYKC--------EECGKAFSQSSILTKHKIIHSVEKPYKCEE 1031

Query: 630  CAKSFRSPSKLERHYLIHAGQKPFECSVCGKTFRQAPHWKRHQLTHFKERP 680
            C K+F   S L RH  IH G+KP++C  CGK F Q  +  RH+  H +E+P
Sbjct: 1032 CGKAFNQSSHLTRHKTIHTGEKPYKCEECGKAFIQCSYLIRHKTIHTREKP 1082



 Score =  217 bits (553), Expect = 3e-56
 Identities = 194/732 (26%), Positives = 315/732 (43%), Gaps = 111/732 (15%)

Query: 11  KIQQCVVANKLPRNRPYVCNICFKHFETPSKLARHYLIHTGQKPFECDVCHKTFRQLVHL 70
           K+ QC  A +    + + CN   K F   S   R+ + HT +K F+C  C K+F  L  L
Sbjct: 8   KLNQCRTATQ---RKIFQCNKHMKVFHKYSN--RNKVRHTKKKTFKCIKCSKSFFMLSCL 62

Query: 71  ERHQLTHSLP--FKCSICQRHFKNLKTFVKHQQLHNETYQNNVKQVRRLLEAKQEKSMYG 128
            RH+  H     +KC    + FK+  T  KH+ +H E      K+     +         
Sbjct: 63  IRHKRIHIRQNIYKCEERGKAFKSFSTLTKHKIIHTEDKPYKYKKCGNAFKFS------- 115

Query: 129 VYNTFTTEERWALHPCSKSDPMYSMKRRKNIHACTICGKMFPSQSKLDRHVLIHTGQRPF 188
             +TFT  +R              +   +    C  CGK F   S L  H  IHTG++ +
Sbjct: 116 --STFTKHKR--------------IHTGETPFRCEECGKAFNQSSNLTDHKRIHTGEKTY 159

Query: 189 KCVLCTKSFRQSTHLKIHQLTHSEERPFQCCFCQKGFKIQSKLLKHKQIHTRNKAFRALL 248
           KC  C K+F+ S++   H++ H+ E+P++C  C K F   S L KHK IHT  K ++   
Sbjct: 160 KCEECGKAFKGSSNFNAHKVIHTAEKPYKCEDCGKTFNHFSALRKHKIIHTGKKPYKREE 219

Query: 249 LKKRRTESRPLPNK--LNANQGGFENGEIGES-EENNPLDVHSIYIV---PFQCPKCEKC 302
             K  ++S  L     ++  +  ++  E G++ + ++ L VH +      P++C +C K 
Sbjct: 220 CGKAFSQSSTLRKHEIIHTGEKPYKCEECGKAFKWSSKLTVHKVVHTGEKPYKCEECGKA 279

Query: 303 FESEQILNEHSCFAARSGKIPSRFK---RSYNYKTIVKKILAKLKRARSKKLDNFQSEKK 359
           F     L +H      +GK P + +   +++N  + + K   K+     K     +  K 
Sbjct: 280 FSQFSTLKKHKII--HTGKKPYKCEECGKAFNSSSTLMK--HKIIHTGEKPYKCEECGKA 335

Query: 360 VFKKSFL-RNCDLISGEQ--SSEQTQRTF--VGSLGKHGTYKTIGNRKKKTLTLPFSWQN 414
             + S L R+  + +GE+    E+  + F     L +H   K I   KK     P+  + 
Sbjct: 336 FRQSSHLTRHKAIHTGEKPYKCEECGKAFNHFSDLRRH---KIIHTGKK-----PYKCEE 387

Query: 415 MGKNLKGILTTENILSIDNSVNKKDLSICGS---------------SGEEFFNNCEVLQC 459
            GK      T  N   I           CG                +GE+    C+  +C
Sbjct: 388 CGKAFSQSSTLRNHQIIHTGEKPYKCEECGKAFKWSSKLTVHKVIHTGEK---PCKCEEC 444

Query: 460 G-----FSVPREN--IRTRHKICPCDKCEKVFPSISKLKRHYLIHTGQRPFGCNICGKSF 512
           G     FS  R++  I TR K+  C++C K F + S L +H +IHTG++P+ C  CGK+F
Sbjct: 445 GKAFKHFSALRKHKVIHTREKLYKCEECGKAFNNSSILAKHKIIHTGKKPYKCEECGKAF 504

Query: 513 RQSAHLKRHEQTHNEKSPY-ASLCQVEFGNFNNLSNHS---GNNVNYNASQQCQA----- 563
           RQS+HL RH+  H  + PY    C   F +F+ L  H         Y   +  +A     
Sbjct: 505 RQSSHLTRHKAIHTGEKPYKCEECGKAFSHFSALRRHKIIHTGKKPYKCEECGKAFSHFS 564

Query: 564 ---------PGVQKYEVSESDQMSGVKAE-SQDFIPGSTGQPCLPNVLLESEQSNPFCSY 613
                     G + Y+  E  +     ++ +   +  +  +PC      + E+      +
Sbjct: 565 ALRRHKIIHTGEKPYKCEECGKAFKWSSKLTVHKVIHTAEKPC------KCEECGKSFKH 618

Query: 614 SEHQEKNDVF-----LYRCSVCAKSFRSPSKLERHYLIHAGQKPFECSVCGKTFRQAPHW 668
                K+ V      LY+C  C K+F S S L +H +IH G+KP++C  CGK F+ +   
Sbjct: 619 FSALRKHKVIHTREKLYKCEECVKAFNSFSALMKHKVIHTGEKPYKCEECGKAFKWSSKL 678

Query: 669 KRHQLTHFKERP 680
             H++ H  E+P
Sbjct: 679 TVHKVIHTGEKP 690



 Score =  177 bits (448), Expect = 4e-44
 Identities = 147/536 (27%), Positives = 242/536 (45%), Gaps = 80/536 (14%)

Query: 8    KMLKIQQCVVA----NKLPRNR-------PYVCNICFKHFETPSKLARHYLIHTGQKPFE 56
            K+ K ++CV A    + L +++       PY C  C K F+  SKL  H +IHTG+KP +
Sbjct: 633  KLYKCEECVKAFNSFSALMKHKVIHTGEKPYKCEECGKAFKWSSKLTVHKVIHTGEKPCK 692

Query: 57   CDVCHKTFRQLVHLERHQLTHS--LPFKCSICQRHFKNLKTFVKHQQLHNETYQNNVKQV 114
            C+ C K F+    L +H++ H+   P+KC  C + F    +  KH+ +H+       ++ 
Sbjct: 693  CEECGKAFKHFSALRKHKVIHTGKKPYKCEECGKAFSQSSSLRKHEIIHSGEKPYKCEEC 752

Query: 115  RRLLEAKQEKSMYGVYNTFTTEERWALHPCSKSDPMYS-MKRRKNIHA------CTICGK 167
             +  +   + +++ V +T   E+      C K+   +S +++ K IH       C  CGK
Sbjct: 753  GKAFKWLSKLTVHKVIHT--AEKPCKCEECGKAFKHFSALRKHKIIHTGKKPYKCEECGK 810

Query: 168  MFPSQSKLDRHVLIHTGQRPFKCVLCTKSFRQSTHLKIHQLTHSEERPFQCCFCQKGFKI 227
             F   S L +H +IHTG++P+KC  C K+F+QS+HL  H+  H+ E+P++C  C K F  
Sbjct: 811  AFNDSSTLMKHKIIHTGKKPYKCAECGKAFKQSSHLTRHKAIHTGEKPYKCEECGKDFNN 870

Query: 228  QSKLLKHKQIHTRNKAFRAL-LLKKRRTESRPLPNKLNANQGGFENGEIGESEENNPLDV 286
             S L KHK IHTR K ++    +K     S  + +K+         GE            
Sbjct: 871  SSTLKKHKLIHTREKLYKCEECVKAFNNFSALMKHKI------IHTGE------------ 912

Query: 287  HSIYIVPFQCPKCEKCFESEQILNEHSCFAARSGKIPSRFK---RSYNYKTIVKKILAKL 343
                  P++C +C K F+    L EH      +G+ P + +   +++ + + ++K   K+
Sbjct: 913  -----KPYKCEECGKAFKWSSKLTEHKVI--HTGEKPCKCEECDKAFKHFSALRK--HKV 963

Query: 344  KRARSKKLDNFQSEKKVFKKSFLRNCDLI-SGEQ--SSEQTQRTFVGS--LGKHGTYKTI 398
                 K     +  K     S L    +I +GE+    E+  + F  S  L KH   K I
Sbjct: 964  IHTGKKPYQCDECGKAFNNSSTLTKHKIIHTGEKPYKCEECGKAFSQSSILTKH---KII 1020

Query: 399  GNRKKKTLTLPFSWQNMGK--NLKGILTTENILSIDNSVNKKDLSICGSSGEEFFNNCEV 456
             + +K     P+  +  GK  N    LT    +       K     C   G+ F      
Sbjct: 1021 HSVEK-----PYKCEECGKAFNQSSHLTRHKTIHTGEKPYK-----CEECGKAF------ 1064

Query: 457  LQCGFSVPRENIRTRHKICPCDKCEKVFPSISKLKRHYLIHTGQRPFGCNICGKSF 512
            +QC + +  + I TR K     K  K+  +   L     IHTG++P+ C  C K+F
Sbjct: 1065 IQCSYLIRHKTIHTREKPTNVKKVPKLLSNPHTLLDK-TIHTGEKPYKCEECAKAF 1119


>gi|239751718 PREDICTED: similar to hCG1773661 [Homo sapiens]
          Length = 1119

 Score =  251 bits (640), Expect = 2e-66
 Identities = 190/687 (27%), Positives = 310/687 (45%), Gaps = 100/687 (14%)

Query: 25  RPYVCNICFKHFETPSKLARHYLIHTGQKPFECDVCHKTFRQLVHLERHQLTHS--LPFK 82
           +PY C  C K F   S L RH  IHTG+KP++C+ C K F     L RH++ H+   P+K
Sbjct: 325 KPYKCEECGKAFRQSSHLTRHKAIHTGEKPYKCEECGKAFNHFSDLRRHKIIHTGKKPYK 384

Query: 83  CSICQRHFKNLKTFVKHQQLHNETYQNNVKQVRRLLEAKQEKSMYGVYNTFTTEERWALH 142
           C  C + F    T   HQ +H        ++  +  +   + +++ V +T   E+     
Sbjct: 385 CEECGKAFSQSSTLRNHQIIHTGEKPYKCEECGKAFKWSSKLTVHKVIHT--GEKPCKCE 442

Query: 143 PCSKSDPMYSMKR-------RKNIHACTICGKMFPSQSKLDRHVLIHTGQRPFKCVLCTK 195
            C K+   +S  R       R+ ++ C  CGK F + S L +H +IHTG++P+KC  C K
Sbjct: 443 ECGKAFKHFSALRKHKVIHTREKLYKCEECGKAFNNSSILAKHKIIHTGKKPYKCEECGK 502

Query: 196 SFRQSTHLKIHQLTHSEERPFQCCFCQKGFKIQSKLLKHKQIHTRNKAFRALLLKKRRTE 255
           +FRQS+HL  H+  H+ E+P++C  C K F   S L +HK IHT  K ++     K  + 
Sbjct: 503 AFRQSSHLTRHKAIHTGEKPYKCEECGKAFSHFSALRRHKIIHTGKKPYKCEECGKAFSH 562

Query: 256 SRPLPNK--LNANQGGFENGEIGESEE-NNPLDVHSIYIV---PFQCPKCEKCFESEQIL 309
              L     ++  +  ++  E G++ + ++ L VH +      P +C +C K F+    L
Sbjct: 563 FSALRRHKIIHTGEKPYKCEECGKAFKWSSKLTVHKVIHTAEKPCKCEECGKSFKHFSAL 622

Query: 310 NEHSCFAARSG--KIPSRFKRSYNYKTIVKKILAKLKRARSKKLDNFQSEKKVFKKSFLR 367
            +H     R    K     K   ++  ++K  +        +K    +   K FK S   
Sbjct: 623 RKHKVIHTREKLYKCEECVKAFNSFSALMKHKVIHT----GEKPYKCEECGKAFKWSSKL 678

Query: 368 NCDLI--SGEQ--SSEQTQRTF--VGSLGKHGTYKTIGNRKKKTLTLPFSWQNMGKNLKG 421
               +  +GE+    E+  + F    +L KH   K I   KK     P+  +  GK    
Sbjct: 679 TVHKVIHTGEKPCKCEECGKAFKHFSALRKH---KVIHTGKK-----PYKCEECGK---- 726

Query: 422 ILTTENILSIDNSVNKKDLSICGSSGEEFFNNCEVLQCGFSVPRENIRTRHKI------- 474
                   S  +S+ K ++     SGE+ +  CE  +CG +    +  T HK+       
Sbjct: 727 ------AFSQSSSLRKHEII---HSGEKPYK-CE--ECGKAFKWLSKLTVHKVIHTAEKP 774

Query: 475 CPCDKCEKVFPSISKLKRHYLIHTGQRPFGCNICGKSFRQSAHLKRHEQTHNEKSPY-AS 533
           C C++C K F   S L++H +IHTG++P+ C  CGK+F  S+ L +H+  H  K PY  +
Sbjct: 775 CKCEECGKAFKHFSALRKHKIIHTGKKPYKCEECGKAFNDSSTLMKHKIIHTGKKPYKCA 834

Query: 534 LCQVEFGNFNNLSNHSGNNVNYNASQQCQAPGVQKYEVSESDQMSGVKAESQDFIPGSTG 593
            C   F   ++L+ H   +            G + Y+  E           +DF   ST 
Sbjct: 835 ECGKAFKQSSHLTRHKAIHT-----------GEKPYKCEEC---------GKDFNNSST- 873

Query: 594 QPCLPNVLLESEQSNPFCSYSEHQEKNDVFLYRCSVCAKSFRSPSKLERHYLIHAGQKPF 653
                + L+ + +                 LY+C  C K+F + S L +H +IH G+KP+
Sbjct: 874 --LKKHKLIHTREK----------------LYKCEECVKAFNNFSALMKHKIIHTGEKPY 915

Query: 654 ECSVCGKTFRQAPHWKRHQLTHFKERP 680
           +C  CGK F+ +     H++ H  E+P
Sbjct: 916 KCEECGKAFKWSSKLTEHKVIHTGEKP 942



 Score =  249 bits (635), Expect = 8e-66
 Identities = 196/711 (27%), Positives = 307/711 (43%), Gaps = 92/711 (12%)

Query: 25   RPYVCNICFKHFETPSKLARHYLIHTGQKPFECDVCHKTFRQLVHLERHQLTHSLP--FK 82
            +PY C  C K F+  SKL  H +IHTG+KP +C+ C K F+    L +H++ H+    +K
Sbjct: 409  KPYKCEECGKAFKWSSKLTVHKVIHTGEKPCKCEECGKAFKHFSALRKHKVIHTREKLYK 468

Query: 83   CSICQRHFKNLKTFVKHQQLHNETYQNNVKQVRRLLEAKQEKSMYGVYNTFTTEERWALH 142
            C  C + F N     KH+ +H        ++  +        + +   +T   E+ +   
Sbjct: 469  CEECGKAFNNSSILAKHKIIHTGKKPYKCEECGKAFRQSSHLTRHKAIHT--GEKPYKCE 526

Query: 143  PCSKSDPMYS-MKRRKNIHA------CTICGKMFPSQSKLDRHVLIHTGQRPFKCVLCTK 195
             C K+   +S ++R K IH       C  CGK F   S L RH +IHTG++P+KC  C K
Sbjct: 527  ECGKAFSHFSALRRHKIIHTGKKPYKCEECGKAFSHFSALRRHKIIHTGEKPYKCEECGK 586

Query: 196  SFRQSTHLKIHQLTHSEERPFQCCFCQKGFKIQSKLLKHKQIHTRNKAFRAL-LLKKRRT 254
            +F+ S+ L +H++ H+ E+P +C  C K FK  S L KHK IHTR K ++    +K   +
Sbjct: 587  AFKWSSKLTVHKVIHTAEKPCKCEECGKSFKHFSALRKHKVIHTREKLYKCEECVKAFNS 646

Query: 255  ESRPLPNK-LNANQGGFENGEIGESEE-NNPLDVHSIYIV-------------------- 292
             S  + +K ++  +  ++  E G++ + ++ L VH +                       
Sbjct: 647  FSALMKHKVIHTGEKPYKCEECGKAFKWSSKLTVHKVIHTGEKPCKCEECGKAFKHFSAL 706

Query: 293  -----------PFQCPKCEKCFESEQILNEHSCFAARSGKIPSRFKRSYN-YKTIVKKIL 340
                       P++C +C K F     L +H      SG+ P + +     +K + K  +
Sbjct: 707  RKHKVIHTGKKPYKCEECGKAFSQSSSLRKHEII--HSGEKPYKCEECGKAFKWLSKLTV 764

Query: 341  AKLKRARSKKLDNFQSEKKVFKKSFLRNCDLI-SGEQ--SSEQTQRTFVGS--LGKHGTY 395
             K+     K     +  K     S LR   +I +G++    E+  + F  S  L KH   
Sbjct: 765  HKVIHTAEKPCKCEECGKAFKHFSALRKHKIIHTGKKPYKCEECGKAFNDSSTLMKH--- 821

Query: 396  KTIGNRKKKTLTLPFSWQNMGKNLKGILTTENILSIDNSVNKKDLSICGSSGEEFFNNCE 455
            K I   KK     P+     GK  K         +I           CG      FNN  
Sbjct: 822  KIIHTGKK-----PYKCAECGKAFKQSSHLTRHKAIHTGEKPYKCEECGKD----FNNSS 872

Query: 456  VLQCGFSVPRENIRTRHKICPCDKCEKVFPSISKLKRHYLIHTGQRPFGCNICGKSFRQS 515
             L+       + I TR K+  C++C K F + S L +H +IHTG++P+ C  CGK+F+ S
Sbjct: 873  TLK-----KHKLIHTREKLYKCEECVKAFNNFSALMKHKIIHTGEKPYKCEECGKAFKWS 927

Query: 516  AHLKRHEQTH-NEKSPYASLCQVEFGNFNNLSNHSGNNVNYNASQQCQAPGVQKYEVSES 574
            + L  H+  H  EK      C   F +F+ L  H   +       QC        E  ++
Sbjct: 928  SKLTEHKVIHTGEKPCKCEECDKAFKHFSALRKHKVIHTG-KKPYQCD-------ECGKA 979

Query: 575  DQMSGVKAESQDFIPGSTGQPCLPNVLLESEQSNPFCSYSEHQEKNDVF-----LYRCSV 629
               S    + +    G     C        E+     S S    K+ +       Y+C  
Sbjct: 980  FNNSSTLTKHKIIHTGEKPYKC--------EECGKAFSQSSILTKHKIIHSVEKPYKCEE 1031

Query: 630  CAKSFRSPSKLERHYLIHAGQKPFECSVCGKTFRQAPHWKRHQLTHFKERP 680
            C K+F   S L RH  IH G+KP++C  CGK F Q  +  RH+  H +E+P
Sbjct: 1032 CGKAFNQSSHLTRHKTIHTGEKPYKCEECGKAFIQCSYLIRHKTIHTREKP 1082



 Score =  217 bits (553), Expect = 3e-56
 Identities = 194/732 (26%), Positives = 315/732 (43%), Gaps = 111/732 (15%)

Query: 11  KIQQCVVANKLPRNRPYVCNICFKHFETPSKLARHYLIHTGQKPFECDVCHKTFRQLVHL 70
           K+ QC  A +    + + CN   K F   S   R+ + HT +K F+C  C K+F  L  L
Sbjct: 8   KLNQCRTATQ---RKIFQCNKHMKVFHKYSN--RNKVRHTKKKTFKCIKCSKSFFMLSCL 62

Query: 71  ERHQLTHSLP--FKCSICQRHFKNLKTFVKHQQLHNETYQNNVKQVRRLLEAKQEKSMYG 128
            RH+  H     +KC    + FK+  T  KH+ +H E      K+     +         
Sbjct: 63  IRHKRIHIRQNIYKCEERGKAFKSFSTLTKHKIIHTEDKPYKYKKCGNAFKFS------- 115

Query: 129 VYNTFTTEERWALHPCSKSDPMYSMKRRKNIHACTICGKMFPSQSKLDRHVLIHTGQRPF 188
             +TFT  +R              +   +    C  CGK F   S L  H  IHTG++ +
Sbjct: 116 --STFTKHKR--------------IHTGETPFRCEECGKAFNQSSNLTDHKRIHTGEKTY 159

Query: 189 KCVLCTKSFRQSTHLKIHQLTHSEERPFQCCFCQKGFKIQSKLLKHKQIHTRNKAFRALL 248
           KC  C K+F+ S++   H++ H+ E+P++C  C K F   S L KHK IHT  K ++   
Sbjct: 160 KCEECGKAFKGSSNFNAHKVIHTAEKPYKCEDCGKTFNHFSALRKHKIIHTGKKPYKREE 219

Query: 249 LKKRRTESRPLPNK--LNANQGGFENGEIGES-EENNPLDVHSIYIV---PFQCPKCEKC 302
             K  ++S  L     ++  +  ++  E G++ + ++ L VH +      P++C +C K 
Sbjct: 220 CGKAFSQSSTLRKHEIIHTGEKPYKCEECGKAFKWSSKLTVHKVVHTGEKPYKCEECGKA 279

Query: 303 FESEQILNEHSCFAARSGKIPSRFK---RSYNYKTIVKKILAKLKRARSKKLDNFQSEKK 359
           F     L +H      +GK P + +   +++N  + + K   K+     K     +  K 
Sbjct: 280 FSQFSTLKKHKII--HTGKKPYKCEECGKAFNSSSTLMK--HKIIHTGEKPYKCEECGKA 335

Query: 360 VFKKSFL-RNCDLISGEQ--SSEQTQRTF--VGSLGKHGTYKTIGNRKKKTLTLPFSWQN 414
             + S L R+  + +GE+    E+  + F     L +H   K I   KK     P+  + 
Sbjct: 336 FRQSSHLTRHKAIHTGEKPYKCEECGKAFNHFSDLRRH---KIIHTGKK-----PYKCEE 387

Query: 415 MGKNLKGILTTENILSIDNSVNKKDLSICGS---------------SGEEFFNNCEVLQC 459
            GK      T  N   I           CG                +GE+    C+  +C
Sbjct: 388 CGKAFSQSSTLRNHQIIHTGEKPYKCEECGKAFKWSSKLTVHKVIHTGEK---PCKCEEC 444

Query: 460 G-----FSVPREN--IRTRHKICPCDKCEKVFPSISKLKRHYLIHTGQRPFGCNICGKSF 512
           G     FS  R++  I TR K+  C++C K F + S L +H +IHTG++P+ C  CGK+F
Sbjct: 445 GKAFKHFSALRKHKVIHTREKLYKCEECGKAFNNSSILAKHKIIHTGKKPYKCEECGKAF 504

Query: 513 RQSAHLKRHEQTHNEKSPY-ASLCQVEFGNFNNLSNHS---GNNVNYNASQQCQA----- 563
           RQS+HL RH+  H  + PY    C   F +F+ L  H         Y   +  +A     
Sbjct: 505 RQSSHLTRHKAIHTGEKPYKCEECGKAFSHFSALRRHKIIHTGKKPYKCEECGKAFSHFS 564

Query: 564 ---------PGVQKYEVSESDQMSGVKAE-SQDFIPGSTGQPCLPNVLLESEQSNPFCSY 613
                     G + Y+  E  +     ++ +   +  +  +PC      + E+      +
Sbjct: 565 ALRRHKIIHTGEKPYKCEECGKAFKWSSKLTVHKVIHTAEKPC------KCEECGKSFKH 618

Query: 614 SEHQEKNDVF-----LYRCSVCAKSFRSPSKLERHYLIHAGQKPFECSVCGKTFRQAPHW 668
                K+ V      LY+C  C K+F S S L +H +IH G+KP++C  CGK F+ +   
Sbjct: 619 FSALRKHKVIHTREKLYKCEECVKAFNSFSALMKHKVIHTGEKPYKCEECGKAFKWSSKL 678

Query: 669 KRHQLTHFKERP 680
             H++ H  E+P
Sbjct: 679 TVHKVIHTGEKP 690



 Score =  177 bits (448), Expect = 4e-44
 Identities = 147/536 (27%), Positives = 242/536 (45%), Gaps = 80/536 (14%)

Query: 8    KMLKIQQCVVA----NKLPRNR-------PYVCNICFKHFETPSKLARHYLIHTGQKPFE 56
            K+ K ++CV A    + L +++       PY C  C K F+  SKL  H +IHTG+KP +
Sbjct: 633  KLYKCEECVKAFNSFSALMKHKVIHTGEKPYKCEECGKAFKWSSKLTVHKVIHTGEKPCK 692

Query: 57   CDVCHKTFRQLVHLERHQLTHS--LPFKCSICQRHFKNLKTFVKHQQLHNETYQNNVKQV 114
            C+ C K F+    L +H++ H+   P+KC  C + F    +  KH+ +H+       ++ 
Sbjct: 693  CEECGKAFKHFSALRKHKVIHTGKKPYKCEECGKAFSQSSSLRKHEIIHSGEKPYKCEEC 752

Query: 115  RRLLEAKQEKSMYGVYNTFTTEERWALHPCSKSDPMYS-MKRRKNIHA------CTICGK 167
             +  +   + +++ V +T   E+      C K+   +S +++ K IH       C  CGK
Sbjct: 753  GKAFKWLSKLTVHKVIHT--AEKPCKCEECGKAFKHFSALRKHKIIHTGKKPYKCEECGK 810

Query: 168  MFPSQSKLDRHVLIHTGQRPFKCVLCTKSFRQSTHLKIHQLTHSEERPFQCCFCQKGFKI 227
             F   S L +H +IHTG++P+KC  C K+F+QS+HL  H+  H+ E+P++C  C K F  
Sbjct: 811  AFNDSSTLMKHKIIHTGKKPYKCAECGKAFKQSSHLTRHKAIHTGEKPYKCEECGKDFNN 870

Query: 228  QSKLLKHKQIHTRNKAFRAL-LLKKRRTESRPLPNKLNANQGGFENGEIGESEENNPLDV 286
             S L KHK IHTR K ++    +K     S  + +K+         GE            
Sbjct: 871  SSTLKKHKLIHTREKLYKCEECVKAFNNFSALMKHKI------IHTGE------------ 912

Query: 287  HSIYIVPFQCPKCEKCFESEQILNEHSCFAARSGKIPSRFK---RSYNYKTIVKKILAKL 343
                  P++C +C K F+    L EH      +G+ P + +   +++ + + ++K   K+
Sbjct: 913  -----KPYKCEECGKAFKWSSKLTEHKVI--HTGEKPCKCEECDKAFKHFSALRK--HKV 963

Query: 344  KRARSKKLDNFQSEKKVFKKSFLRNCDLI-SGEQ--SSEQTQRTFVGS--LGKHGTYKTI 398
                 K     +  K     S L    +I +GE+    E+  + F  S  L KH   K I
Sbjct: 964  IHTGKKPYQCDECGKAFNNSSTLTKHKIIHTGEKPYKCEECGKAFSQSSILTKH---KII 1020

Query: 399  GNRKKKTLTLPFSWQNMGK--NLKGILTTENILSIDNSVNKKDLSICGSSGEEFFNNCEV 456
             + +K     P+  +  GK  N    LT    +       K     C   G+ F      
Sbjct: 1021 HSVEK-----PYKCEECGKAFNQSSHLTRHKTIHTGEKPYK-----CEECGKAF------ 1064

Query: 457  LQCGFSVPRENIRTRHKICPCDKCEKVFPSISKLKRHYLIHTGQRPFGCNICGKSF 512
            +QC + +  + I TR K     K  K+  +   L     IHTG++P+ C  C K+F
Sbjct: 1065 IQCSYLIRHKTIHTREKPTNVKKVPKLLSNPHTLLDK-TIHTGEKPYKCEECAKAF 1119


>gi|239746221 PREDICTED: hypothetical protein XP_002343677 [Homo
           sapiens]
          Length = 1119

 Score =  251 bits (640), Expect = 2e-66
 Identities = 190/687 (27%), Positives = 310/687 (45%), Gaps = 100/687 (14%)

Query: 25  RPYVCNICFKHFETPSKLARHYLIHTGQKPFECDVCHKTFRQLVHLERHQLTHS--LPFK 82
           +PY C  C K F   S L RH  IHTG+KP++C+ C K F     L RH++ H+   P+K
Sbjct: 325 KPYKCEECGKAFRQSSHLTRHKAIHTGEKPYKCEECGKAFNHFSDLRRHKIIHTGKKPYK 384

Query: 83  CSICQRHFKNLKTFVKHQQLHNETYQNNVKQVRRLLEAKQEKSMYGVYNTFTTEERWALH 142
           C  C + F    T   HQ +H        ++  +  +   + +++ V +T   E+     
Sbjct: 385 CEECGKAFSQSSTLRNHQIIHTGEKPYKCEECGKAFKWSSKLTVHKVIHT--GEKPCKCE 442

Query: 143 PCSKSDPMYSMKR-------RKNIHACTICGKMFPSQSKLDRHVLIHTGQRPFKCVLCTK 195
            C K+   +S  R       R+ ++ C  CGK F + S L +H +IHTG++P+KC  C K
Sbjct: 443 ECGKAFKHFSALRKHKVIHTREKLYKCEECGKAFNNSSILAKHKIIHTGKKPYKCEECGK 502

Query: 196 SFRQSTHLKIHQLTHSEERPFQCCFCQKGFKIQSKLLKHKQIHTRNKAFRALLLKKRRTE 255
           +FRQS+HL  H+  H+ E+P++C  C K F   S L +HK IHT  K ++     K  + 
Sbjct: 503 AFRQSSHLTRHKAIHTGEKPYKCEECGKAFSHFSALRRHKIIHTGKKPYKCEECGKAFSH 562

Query: 256 SRPLPNK--LNANQGGFENGEIGESEE-NNPLDVHSIYIV---PFQCPKCEKCFESEQIL 309
              L     ++  +  ++  E G++ + ++ L VH +      P +C +C K F+    L
Sbjct: 563 FSALRRHKIIHTGEKPYKCEECGKAFKWSSKLTVHKVIHTAEKPCKCEECGKSFKHFSAL 622

Query: 310 NEHSCFAARSG--KIPSRFKRSYNYKTIVKKILAKLKRARSKKLDNFQSEKKVFKKSFLR 367
            +H     R    K     K   ++  ++K  +        +K    +   K FK S   
Sbjct: 623 RKHKVIHTREKLYKCEECVKAFNSFSALMKHKVIHT----GEKPYKCEECGKAFKWSSKL 678

Query: 368 NCDLI--SGEQ--SSEQTQRTF--VGSLGKHGTYKTIGNRKKKTLTLPFSWQNMGKNLKG 421
               +  +GE+    E+  + F    +L KH   K I   KK     P+  +  GK    
Sbjct: 679 TVHKVIHTGEKPCKCEECGKAFKHFSALRKH---KVIHTGKK-----PYKCEECGK---- 726

Query: 422 ILTTENILSIDNSVNKKDLSICGSSGEEFFNNCEVLQCGFSVPRENIRTRHKI------- 474
                   S  +S+ K ++     SGE+ +  CE  +CG +    +  T HK+       
Sbjct: 727 ------AFSQSSSLRKHEII---HSGEKPYK-CE--ECGKAFKWLSKLTVHKVIHTAEKP 774

Query: 475 CPCDKCEKVFPSISKLKRHYLIHTGQRPFGCNICGKSFRQSAHLKRHEQTHNEKSPY-AS 533
           C C++C K F   S L++H +IHTG++P+ C  CGK+F  S+ L +H+  H  K PY  +
Sbjct: 775 CKCEECGKAFKHFSALRKHKIIHTGKKPYKCEECGKAFNDSSTLMKHKIIHTGKKPYKCA 834

Query: 534 LCQVEFGNFNNLSNHSGNNVNYNASQQCQAPGVQKYEVSESDQMSGVKAESQDFIPGSTG 593
            C   F   ++L+ H   +            G + Y+  E           +DF   ST 
Sbjct: 835 ECGKAFKQSSHLTRHKAIHT-----------GEKPYKCEEC---------GKDFNNSST- 873

Query: 594 QPCLPNVLLESEQSNPFCSYSEHQEKNDVFLYRCSVCAKSFRSPSKLERHYLIHAGQKPF 653
                + L+ + +                 LY+C  C K+F + S L +H +IH G+KP+
Sbjct: 874 --LKKHKLIHTREK----------------LYKCEECVKAFNNFSALMKHKIIHTGEKPY 915

Query: 654 ECSVCGKTFRQAPHWKRHQLTHFKERP 680
           +C  CGK F+ +     H++ H  E+P
Sbjct: 916 KCEECGKAFKWSSKLTEHKVIHTGEKP 942



 Score =  249 bits (635), Expect = 8e-66
 Identities = 196/711 (27%), Positives = 307/711 (43%), Gaps = 92/711 (12%)

Query: 25   RPYVCNICFKHFETPSKLARHYLIHTGQKPFECDVCHKTFRQLVHLERHQLTHSLP--FK 82
            +PY C  C K F+  SKL  H +IHTG+KP +C+ C K F+    L +H++ H+    +K
Sbjct: 409  KPYKCEECGKAFKWSSKLTVHKVIHTGEKPCKCEECGKAFKHFSALRKHKVIHTREKLYK 468

Query: 83   CSICQRHFKNLKTFVKHQQLHNETYQNNVKQVRRLLEAKQEKSMYGVYNTFTTEERWALH 142
            C  C + F N     KH+ +H        ++  +        + +   +T   E+ +   
Sbjct: 469  CEECGKAFNNSSILAKHKIIHTGKKPYKCEECGKAFRQSSHLTRHKAIHT--GEKPYKCE 526

Query: 143  PCSKSDPMYS-MKRRKNIHA------CTICGKMFPSQSKLDRHVLIHTGQRPFKCVLCTK 195
             C K+   +S ++R K IH       C  CGK F   S L RH +IHTG++P+KC  C K
Sbjct: 527  ECGKAFSHFSALRRHKIIHTGKKPYKCEECGKAFSHFSALRRHKIIHTGEKPYKCEECGK 586

Query: 196  SFRQSTHLKIHQLTHSEERPFQCCFCQKGFKIQSKLLKHKQIHTRNKAFRAL-LLKKRRT 254
            +F+ S+ L +H++ H+ E+P +C  C K FK  S L KHK IHTR K ++    +K   +
Sbjct: 587  AFKWSSKLTVHKVIHTAEKPCKCEECGKSFKHFSALRKHKVIHTREKLYKCEECVKAFNS 646

Query: 255  ESRPLPNK-LNANQGGFENGEIGESEE-NNPLDVHSIYIV-------------------- 292
             S  + +K ++  +  ++  E G++ + ++ L VH +                       
Sbjct: 647  FSALMKHKVIHTGEKPYKCEECGKAFKWSSKLTVHKVIHTGEKPCKCEECGKAFKHFSAL 706

Query: 293  -----------PFQCPKCEKCFESEQILNEHSCFAARSGKIPSRFKRSYN-YKTIVKKIL 340
                       P++C +C K F     L +H      SG+ P + +     +K + K  +
Sbjct: 707  RKHKVIHTGKKPYKCEECGKAFSQSSSLRKHEII--HSGEKPYKCEECGKAFKWLSKLTV 764

Query: 341  AKLKRARSKKLDNFQSEKKVFKKSFLRNCDLI-SGEQ--SSEQTQRTFVGS--LGKHGTY 395
             K+     K     +  K     S LR   +I +G++    E+  + F  S  L KH   
Sbjct: 765  HKVIHTAEKPCKCEECGKAFKHFSALRKHKIIHTGKKPYKCEECGKAFNDSSTLMKH--- 821

Query: 396  KTIGNRKKKTLTLPFSWQNMGKNLKGILTTENILSIDNSVNKKDLSICGSSGEEFFNNCE 455
            K I   KK     P+     GK  K         +I           CG      FNN  
Sbjct: 822  KIIHTGKK-----PYKCAECGKAFKQSSHLTRHKAIHTGEKPYKCEECGKD----FNNSS 872

Query: 456  VLQCGFSVPRENIRTRHKICPCDKCEKVFPSISKLKRHYLIHTGQRPFGCNICGKSFRQS 515
             L+       + I TR K+  C++C K F + S L +H +IHTG++P+ C  CGK+F+ S
Sbjct: 873  TLK-----KHKLIHTREKLYKCEECVKAFNNFSALMKHKIIHTGEKPYKCEECGKAFKWS 927

Query: 516  AHLKRHEQTH-NEKSPYASLCQVEFGNFNNLSNHSGNNVNYNASQQCQAPGVQKYEVSES 574
            + L  H+  H  EK      C   F +F+ L  H   +       QC        E  ++
Sbjct: 928  SKLTEHKVIHTGEKPCKCEECDKAFKHFSALRKHKVIHTG-KKPYQCD-------ECGKA 979

Query: 575  DQMSGVKAESQDFIPGSTGQPCLPNVLLESEQSNPFCSYSEHQEKNDVF-----LYRCSV 629
               S    + +    G     C        E+     S S    K+ +       Y+C  
Sbjct: 980  FNNSSTLTKHKIIHTGEKPYKC--------EECGKAFSQSSILTKHKIIHSVEKPYKCEE 1031

Query: 630  CAKSFRSPSKLERHYLIHAGQKPFECSVCGKTFRQAPHWKRHQLTHFKERP 680
            C K+F   S L RH  IH G+KP++C  CGK F Q  +  RH+  H +E+P
Sbjct: 1032 CGKAFNQSSHLTRHKTIHTGEKPYKCEECGKAFIQCSYLIRHKTIHTREKP 1082



 Score =  217 bits (553), Expect = 3e-56
 Identities = 194/732 (26%), Positives = 315/732 (43%), Gaps = 111/732 (15%)

Query: 11  KIQQCVVANKLPRNRPYVCNICFKHFETPSKLARHYLIHTGQKPFECDVCHKTFRQLVHL 70
           K+ QC  A +    + + CN   K F   S   R+ + HT +K F+C  C K+F  L  L
Sbjct: 8   KLNQCRTATQ---RKIFQCNKHMKVFHKYSN--RNKVRHTKKKTFKCIKCSKSFFMLSCL 62

Query: 71  ERHQLTHSLP--FKCSICQRHFKNLKTFVKHQQLHNETYQNNVKQVRRLLEAKQEKSMYG 128
            RH+  H     +KC    + FK+  T  KH+ +H E      K+     +         
Sbjct: 63  IRHKRIHIRQNIYKCEERGKAFKSFSTLTKHKIIHTEDKPYKYKKCGNAFKFS------- 115

Query: 129 VYNTFTTEERWALHPCSKSDPMYSMKRRKNIHACTICGKMFPSQSKLDRHVLIHTGQRPF 188
             +TFT  +R              +   +    C  CGK F   S L  H  IHTG++ +
Sbjct: 116 --STFTKHKR--------------IHTGETPFRCEECGKAFNQSSNLTDHKRIHTGEKTY 159

Query: 189 KCVLCTKSFRQSTHLKIHQLTHSEERPFQCCFCQKGFKIQSKLLKHKQIHTRNKAFRALL 248
           KC  C K+F+ S++   H++ H+ E+P++C  C K F   S L KHK IHT  K ++   
Sbjct: 160 KCEECGKAFKGSSNFNAHKVIHTAEKPYKCEDCGKTFNHFSALRKHKIIHTGKKPYKREE 219

Query: 249 LKKRRTESRPLPNK--LNANQGGFENGEIGES-EENNPLDVHSIYIV---PFQCPKCEKC 302
             K  ++S  L     ++  +  ++  E G++ + ++ L VH +      P++C +C K 
Sbjct: 220 CGKAFSQSSTLRKHEIIHTGEKPYKCEECGKAFKWSSKLTVHKVVHTGEKPYKCEECGKA 279

Query: 303 FESEQILNEHSCFAARSGKIPSRFK---RSYNYKTIVKKILAKLKRARSKKLDNFQSEKK 359
           F     L +H      +GK P + +   +++N  + + K   K+     K     +  K 
Sbjct: 280 FSQFSTLKKHKII--HTGKKPYKCEECGKAFNSSSTLMK--HKIIHTGEKPYKCEECGKA 335

Query: 360 VFKKSFL-RNCDLISGEQ--SSEQTQRTF--VGSLGKHGTYKTIGNRKKKTLTLPFSWQN 414
             + S L R+  + +GE+    E+  + F     L +H   K I   KK     P+  + 
Sbjct: 336 FRQSSHLTRHKAIHTGEKPYKCEECGKAFNHFSDLRRH---KIIHTGKK-----PYKCEE 387

Query: 415 MGKNLKGILTTENILSIDNSVNKKDLSICGS---------------SGEEFFNNCEVLQC 459
            GK      T  N   I           CG                +GE+    C+  +C
Sbjct: 388 CGKAFSQSSTLRNHQIIHTGEKPYKCEECGKAFKWSSKLTVHKVIHTGEK---PCKCEEC 444

Query: 460 G-----FSVPREN--IRTRHKICPCDKCEKVFPSISKLKRHYLIHTGQRPFGCNICGKSF 512
           G     FS  R++  I TR K+  C++C K F + S L +H +IHTG++P+ C  CGK+F
Sbjct: 445 GKAFKHFSALRKHKVIHTREKLYKCEECGKAFNNSSILAKHKIIHTGKKPYKCEECGKAF 504

Query: 513 RQSAHLKRHEQTHNEKSPY-ASLCQVEFGNFNNLSNHS---GNNVNYNASQQCQA----- 563
           RQS+HL RH+  H  + PY    C   F +F+ L  H         Y   +  +A     
Sbjct: 505 RQSSHLTRHKAIHTGEKPYKCEECGKAFSHFSALRRHKIIHTGKKPYKCEECGKAFSHFS 564

Query: 564 ---------PGVQKYEVSESDQMSGVKAE-SQDFIPGSTGQPCLPNVLLESEQSNPFCSY 613
                     G + Y+  E  +     ++ +   +  +  +PC      + E+      +
Sbjct: 565 ALRRHKIIHTGEKPYKCEECGKAFKWSSKLTVHKVIHTAEKPC------KCEECGKSFKH 618

Query: 614 SEHQEKNDVF-----LYRCSVCAKSFRSPSKLERHYLIHAGQKPFECSVCGKTFRQAPHW 668
                K+ V      LY+C  C K+F S S L +H +IH G+KP++C  CGK F+ +   
Sbjct: 619 FSALRKHKVIHTREKLYKCEECVKAFNSFSALMKHKVIHTGEKPYKCEECGKAFKWSSKL 678

Query: 669 KRHQLTHFKERP 680
             H++ H  E+P
Sbjct: 679 TVHKVIHTGEKP 690



 Score =  177 bits (448), Expect = 4e-44
 Identities = 147/536 (27%), Positives = 242/536 (45%), Gaps = 80/536 (14%)

Query: 8    KMLKIQQCVVA----NKLPRNR-------PYVCNICFKHFETPSKLARHYLIHTGQKPFE 56
            K+ K ++CV A    + L +++       PY C  C K F+  SKL  H +IHTG+KP +
Sbjct: 633  KLYKCEECVKAFNSFSALMKHKVIHTGEKPYKCEECGKAFKWSSKLTVHKVIHTGEKPCK 692

Query: 57   CDVCHKTFRQLVHLERHQLTHS--LPFKCSICQRHFKNLKTFVKHQQLHNETYQNNVKQV 114
            C+ C K F+    L +H++ H+   P+KC  C + F    +  KH+ +H+       ++ 
Sbjct: 693  CEECGKAFKHFSALRKHKVIHTGKKPYKCEECGKAFSQSSSLRKHEIIHSGEKPYKCEEC 752

Query: 115  RRLLEAKQEKSMYGVYNTFTTEERWALHPCSKSDPMYS-MKRRKNIHA------CTICGK 167
             +  +   + +++ V +T   E+      C K+   +S +++ K IH       C  CGK
Sbjct: 753  GKAFKWLSKLTVHKVIHT--AEKPCKCEECGKAFKHFSALRKHKIIHTGKKPYKCEECGK 810

Query: 168  MFPSQSKLDRHVLIHTGQRPFKCVLCTKSFRQSTHLKIHQLTHSEERPFQCCFCQKGFKI 227
             F   S L +H +IHTG++P+KC  C K+F+QS+HL  H+  H+ E+P++C  C K F  
Sbjct: 811  AFNDSSTLMKHKIIHTGKKPYKCAECGKAFKQSSHLTRHKAIHTGEKPYKCEECGKDFNN 870

Query: 228  QSKLLKHKQIHTRNKAFRAL-LLKKRRTESRPLPNKLNANQGGFENGEIGESEENNPLDV 286
             S L KHK IHTR K ++    +K     S  + +K+         GE            
Sbjct: 871  SSTLKKHKLIHTREKLYKCEECVKAFNNFSALMKHKI------IHTGE------------ 912

Query: 287  HSIYIVPFQCPKCEKCFESEQILNEHSCFAARSGKIPSRFK---RSYNYKTIVKKILAKL 343
                  P++C +C K F+    L EH      +G+ P + +   +++ + + ++K   K+
Sbjct: 913  -----KPYKCEECGKAFKWSSKLTEHKVI--HTGEKPCKCEECDKAFKHFSALRK--HKV 963

Query: 344  KRARSKKLDNFQSEKKVFKKSFLRNCDLI-SGEQ--SSEQTQRTFVGS--LGKHGTYKTI 398
                 K     +  K     S L    +I +GE+    E+  + F  S  L KH   K I
Sbjct: 964  IHTGKKPYQCDECGKAFNNSSTLTKHKIIHTGEKPYKCEECGKAFSQSSILTKH---KII 1020

Query: 399  GNRKKKTLTLPFSWQNMGK--NLKGILTTENILSIDNSVNKKDLSICGSSGEEFFNNCEV 456
             + +K     P+  +  GK  N    LT    +       K     C   G+ F      
Sbjct: 1021 HSVEK-----PYKCEECGKAFNQSSHLTRHKTIHTGEKPYK-----CEECGKAF------ 1064

Query: 457  LQCGFSVPRENIRTRHKICPCDKCEKVFPSISKLKRHYLIHTGQRPFGCNICGKSF 512
            +QC + +  + I TR K     K  K+  +   L     IHTG++P+ C  C K+F
Sbjct: 1065 IQCSYLIRHKTIHTREKPTNVKKVPKLLSNPHTLLDK-TIHTGEKPYKCEECAKAF 1119


>gi|118600985 zinc finger protein 91 [Homo sapiens]
          Length = 1191

 Score =  245 bits (625), Expect = 1e-64
 Identities = 186/688 (27%), Positives = 298/688 (43%), Gaps = 74/688 (10%)

Query: 25   RPYVCNICFKHFETPSKLARHYLIHTGQKPFECDVCHKTFRQLVHLERHQLTHSL--PFK 82
            +PY C  C K F   S L +H +IHTG+KP++ + C K FRQ + L +H++ HS   P+K
Sbjct: 488  KPYKCEECGKAFRQSSTLTKHKIIHTGEKPYKFEECGKAFRQSLTLNKHKIIHSREKPYK 547

Query: 83   CSICQRHFKNLKTFVKHQQLHNETYQNNVKQVRRLLEAKQEKSMYGVYNTFTTEERWALH 142
            C  C + FK   T   H+ +H        ++  +        S + + +T   E+ +   
Sbjct: 548  CKECGKAFKQFSTLTTHKIIHAGKKLYKCEECGKAFNHSSSLSTHKIIHT--GEKSYKCE 605

Query: 143  PCSKSDPMYS-MKRRKNIHA------CTICGKMFPSQSKLDRHVLIHTGQRPFKCVLCTK 195
             C K+    S ++R K IH       C  CGK F   S L +H  IHTG++P+KC  C K
Sbjct: 606  ECGKAFLWSSTLRRHKRIHTGEKPYKCEECGKAFSHSSALAKHKRIHTGEKPYKCKECGK 665

Query: 196  SFRQSTHLKIHQLTHSEERPFQCCFCQKGFKIQSKLLKHKQIHTRNKAFRALLLKK--RR 253
            +F  S+ L  H++TH+EE+P++C  C K FK  S L KHK IH   K ++     K   R
Sbjct: 666  AFSNSSTLANHKITHTEEKPYKCKECDKTFKRLSTLTKHKIIHAGEKLYKCEECGKAFNR 725

Query: 254  TESRPLPNKLNANQGGFENGEIGESEE-NNPLDVHSIYIV---PFQCPKCEKCFESEQIL 309
            + +  +   ++  +  ++  E G++   ++ L  H        PF+C +C K F     L
Sbjct: 726  SSNLTIHKFIHTGEKPYKCEECGKAFNWSSSLTKHKRIHTREKPFKCKECGKAFIWSSTL 785

Query: 310  NEHSCF--------AARSGKIPSRFKRSYNYKTIVKKILAKLKRARSKKLDNFQSEKKVF 361
              H               GK  SR      +KTI             +K    +   K F
Sbjct: 786  TRHKRIHTGEKPYKCEECGKAFSRSSTLTKHKTI----------HTGEKPYKCKECGKAF 835

Query: 362  KKS--FLRNCDLISGEQ--SSEQTQRTFVGSLGKHGTYKTIGNRKKKTLT----LPFSWQ 413
            K S    ++  + +GE+    E+  + F  S     T+K I  ++K + +      F W 
Sbjct: 836  KHSSALAKHKIIHAGEKLYKCEECGKAFNQS-SNLTTHKIIHTKEKPSKSEECDKAFIWS 894

Query: 414  NMGKNLKGILTTENILSIDNSVNKKDLSICGSSGEEFFNNCEVLQCGFSVPRENIRTRHK 473
            +     K I T E                C   G+ F       Q       + + T  K
Sbjct: 895  STLTEHKRIHTREKTYK------------CEECGKAFS------QPSHLTTHKRMHTGEK 936

Query: 474  ICPCDKCEKVFPSISKLKRHYLIHTGQRPFGCNICGKSFRQSAHLKRHEQTHNEKSPY-A 532
               C++C K F   S L  H +IHTG++P+ C  CGK+FR+S+ L  H+  H  + PY  
Sbjct: 937  PYKCEECGKAFSQSSTLTTHKIIHTGEKPYKCEECGKAFRKSSTLTEHKIIHTGEKPYKC 996

Query: 533  SLCQVEFGNFNNLSNHSGNNVNYNASQQCQAPGVQKYEVSESDQMSGVKAESQDFIPGST 592
              C   F   + L+ H+  +       +C+  G      S+      +    + +     
Sbjct: 997  EECGKAFSQSSTLTRHTRMHTG-EKPYKCEECGKAFNRSSKLTTHKIIHTGEKPYKCEEC 1055

Query: 593  GQPCLPNVLLESEQSNPFCSYSEHQEKNDVFLYRCSVCAKSFRSPSKLERHYLIHAGQKP 652
            G+  + +  L   +          +EK     Y+C  C K+F   S L RH  +H G+KP
Sbjct: 1056 GKAFISSSTLNGHKR------IHTREKP----YKCEECGKAFSQSSTLTRHKRLHTGEKP 1105

Query: 653  FECSVCGKTFRQAPHWKRHQLTHFKERP 680
            ++C  CGK F+++    +H++ H  E+P
Sbjct: 1106 YKCGECGKAFKESSALTKHKIIHTGEKP 1133



 Score =  232 bits (591), Expect = 1e-60
 Identities = 193/729 (26%), Positives = 306/729 (41%), Gaps = 96/729 (13%)

Query: 23  RNRPYVCNICFKHFETPSKLARHYLIHTGQKPFECDVCHKTFRQLVHLERHQLTHS--LP 80
           + + Y C  C K F   S L RH  IHTG+KP++C+ C K F     L +H+  H+   P
Sbjct: 262 KEKIYKCEECGKAFLWSSTLTRHKRIHTGEKPYKCEECGKAFSHSSTLAKHKRIHTGEKP 321

Query: 81  FKCSICQRHFKNLKTFVKHQQLHNETYQNNVKQVRRLLEAKQEKSMYGVYNTFTTEERWA 140
           +KC  C + F    T  KH+++H        K+  +        + + +  T T E+ + 
Sbjct: 322 YKCEECGKAFSRSSTLAKHKRIHTGEKPYKCKECGKAFSNSSTLANHKI--THTEEKPYK 379

Query: 141 LHPCSKSDPMYS-MKRRKNIHA------CTICGKMFPSQSKLDRHVLIHTGQRPFKCVLC 193
              C K+    S + + K IHA      C  CGK F   S L  H  IHTG++P+KC  C
Sbjct: 380 CKECDKAFKRLSTLTKHKIIHAGEKLYKCEECGKAFNRSSNLTIHKFIHTGEKPYKCEEC 439

Query: 194 TKSFRQSTHLKIHQLTHSEERPFQCCFCQKGFKIQSKLLKHKQIHTRNKAFRALLLKKRR 253
            K+F  S+ L  H+  H+ E+PF+C  C K F   S L +HK+IHT  K ++     K  
Sbjct: 440 GKAFNWSSSLTKHKRFHTREKPFKCKECGKAFIWSSTLTRHKRIHTGEKPYKCEECGKAF 499

Query: 254 TESRPLPNK--LNANQGGFENGEIGES-EENNPLDVHSIY---IVPFQCPKCEKCFESEQ 307
            +S  L     ++  +  ++  E G++  ++  L+ H I      P++C +C K F+   
Sbjct: 500 RQSSTLTKHKIIHTGEKPYKFEECGKAFRQSLTLNKHKIIHSREKPYKCKECGKAFKQFS 559

Query: 308 ILNEHSCFAA--------------------RSGKIPSRFKRSYNYKTIVKKILAKLKRAR 347
            L  H    A                     + KI    ++SY  +   K  L      R
Sbjct: 560 TLTTHKIIHAGKKLYKCEECGKAFNHSSSLSTHKIIHTGEKSYKCEECGKAFLWSSTLRR 619

Query: 348 SKKLDNFQSEKKVFK--KSFLRNCDLISGEQSSEQTQRTFVGSLGK-HGTYKTIGNRK-K 403
            K++   +   K  +  K+F  +  L   ++     +       GK      T+ N K  
Sbjct: 620 HKRIHTGEKPYKCEECGKAFSHSSALAKHKRIHTGEKPYKCKECGKAFSNSSTLANHKIT 679

Query: 404 KTLTLPFSWQNMGKNLKGI--LTTENILSIDNSVNKKDLSICGSSGEEFFN--------- 452
            T   P+  +   K  K +  LT   I+     + K     CG +     N         
Sbjct: 680 HTEEKPYKCKECDKTFKRLSTLTKHKIIHAGEKLYK--CEECGKAFNRSSNLTIHKFIHT 737

Query: 453 -----NCEVLQCGFS-------VPRENIRTRHKICPCDKCEKVFPSISKLKRHYLIHTGQ 500
                 CE  +CG +          + I TR K   C +C K F   S L RH  IHTG+
Sbjct: 738 GEKPYKCE--ECGKAFNWSSSLTKHKRIHTREKPFKCKECGKAFIWSSTLTRHKRIHTGE 795

Query: 501 RPFGCNICGKSFRQSAHLKRHEQTHNEKSPY-ASLCQVEFGNFNNLSNHSGNNVNYN--A 557
           +P+ C  CGK+F +S+ L +H+  H  + PY    C   F + + L+ H   +       
Sbjct: 796 KPYKCEECGKAFSRSSTLTKHKTIHTGEKPYKCKECGKAFKHSSALAKHKIIHAGEKLYK 855

Query: 558 SQQC-----QAPGVQKYEVSESDQMSGVKAE-SQDFIPGSTGQPCLPNVLLESEQSNPFC 611
            ++C     Q+  +  +++  + +      E  + FI  ST        L E ++ +   
Sbjct: 856 CEECGKAFNQSSNLTTHKIIHTKEKPSKSEECDKAFIWSST--------LTEHKRIHT-- 905

Query: 612 SYSEHQEKNDVFLYRCSVCAKSFRSPSKLERHYLIHAGQKPFECSVCGKTFRQAPHWKRH 671
                +EK     Y+C  C K+F  PS L  H  +H G+KP++C  CGK F Q+     H
Sbjct: 906 -----REKT----YKCEECGKAFSQPSHLTTHKRMHTGEKPYKCEECGKAFSQSSTLTTH 956

Query: 672 QLTHFKERP 680
           ++ H  E+P
Sbjct: 957 KIIHTGEKP 965



 Score =  229 bits (583), Expect = 8e-60
 Identities = 192/721 (26%), Positives = 309/721 (42%), Gaps = 84/721 (11%)

Query: 25   RPYVCNICFKHFETPSKLARHYLIHTGQKPFECDVCHKTFRQLVHLERHQLTHS--LPFK 82
            +PY C  C K F   S LA+H  IHTG+KP++C  C K F     L  H++TH+   P+K
Sbjct: 320  KPYKCEECGKAFSRSSTLAKHKRIHTGEKPYKCKECGKAFSNSSTLANHKITHTEEKPYK 379

Query: 83   CSICQRHFKNLKTFVKHQQLHNETYQNNVKQVRRLLEAKQEKSMYGVYNTFTTEERWALH 142
            C  C + FK L T  KH+ +H        ++  +        +++   +T   E+ +   
Sbjct: 380  CKECDKAFKRLSTLTKHKIIHAGEKLYKCEECGKAFNRSSNLTIHKFIHT--GEKPYKCE 437

Query: 143  PCSKS-DPMYSMKRRKNIHA------CTICGKMFPSQSKLDRHVLIHTGQRPFKCVLCTK 195
             C K+ +   S+ + K  H       C  CGK F   S L RH  IHTG++P+KC  C K
Sbjct: 438  ECGKAFNWSSSLTKHKRFHTREKPFKCKECGKAFIWSSTLTRHKRIHTGEKPYKCEECGK 497

Query: 196  SFRQSTHLKIHQLTHSEERPFQCCFCQKGFKIQSKLLKHKQIHTRNKAFRALLLKKRRTE 255
            +FRQS+ L  H++ H+ E+P++   C K F+    L KHK IH+R K ++     K   +
Sbjct: 498  AFRQSSTLTKHKIIHTGEKPYKFEECGKAFRQSLTLNKHKIIHSREKPYKCKECGKAFKQ 557

Query: 256  SRPLPNK--LNANQGGFENGEIGES-EENNPLDVHSIYIV---PFQCPKCEKCFESEQIL 309
               L     ++A +  ++  E G++   ++ L  H I       ++C +C K F     L
Sbjct: 558  FSTLTTHKIIHAGKKLYKCEECGKAFNHSSSLSTHKIIHTGEKSYKCEECGKAFLWSSTL 617

Query: 310  NEHSCFAARSGKIPSRFK---RSYNYKTIVKKILAKLKRARS--KKLDNFQSEKKVFKKS 364
              H      +G+ P + +   +++++ +     LAK KR  +  K     +  K     S
Sbjct: 618  RRHK--RIHTGEKPYKCEECGKAFSHSSA----LAKHKRIHTGEKPYKCKECGKAFSNSS 671

Query: 365  FLRNCDLISGEQSS---EQTQRTF--VGSLGKHGT-------YKTI----GNRKKKTLTL 408
             L N  +   E+     ++  +TF  + +L KH         YK         +   LT+
Sbjct: 672  TLANHKITHTEEKPYKCKECDKTFKRLSTLTKHKIIHAGEKLYKCEECGKAFNRSSNLTI 731

Query: 409  ---------PFSWQNMGK--NLKGILTTENILSIDNSVNKKDLSICGSSGEEFFNNCEVL 457
                     P+  +  GK  N    LT    +       K     C   G+ F  +  + 
Sbjct: 732  HKFIHTGEKPYKCEECGKAFNWSSSLTKHKRIHTREKPFK-----CKECGKAFIWSSTLT 786

Query: 458  QCGFSVPRENIRTRHKICPCDKCEKVFPSISKLKRHYLIHTGQRPFGCNICGKSFRQSAH 517
            +       + I T  K   C++C K F   S L +H  IHTG++P+ C  CGK+F+ S+ 
Sbjct: 787  R------HKRIHTGEKPYKCEECGKAFSRSSTLTKHKTIHTGEKPYKCKECGKAFKHSSA 840

Query: 518  LKRHEQTH-NEKSPYASLCQVEFGNFNNLSNHS--GNNVNYNASQQCQAPGVQKYEVSES 574
            L +H+  H  EK      C   F   +NL+ H         + S++C    +    ++E 
Sbjct: 841  LAKHKIIHAGEKLYKCEECGKAFNQSSNLTTHKIIHTKEKPSKSEECDKAFIWSSTLTEH 900

Query: 575  DQMSGV----------KAESQDFIPGSTGQPCLPNVLLESEQSNPFCSYSEHQEKNDVFL 624
             ++             KA SQ     +  +        + E+     S S     + +  
Sbjct: 901  KRIHTREKTYKCEECGKAFSQPSHLTTHKRMHTGEKPYKCEECGKAFSQSSTLTTHKIIH 960

Query: 625  -----YRCSVCAKSFRSPSKLERHYLIHAGQKPFECSVCGKTFRQAPHWKRHQLTHFKER 679
                 Y+C  C K+FR  S L  H +IH G+KP++C  CGK F Q+    RH   H  E+
Sbjct: 961  TGEKPYKCEECGKAFRKSSTLTEHKIIHTGEKPYKCEECGKAFSQSSTLTRHTRMHTGEK 1020

Query: 680  P 680
            P
Sbjct: 1021 P 1021



 Score =  222 bits (565), Expect = 1e-57
 Identities = 179/680 (26%), Positives = 283/680 (41%), Gaps = 128/680 (18%)

Query: 27   YVCNICFKHFETPSKLARHYLIHTGQKPFECDVCHKTFRQLVHLERHQLTHS--LPFKCS 84
            Y C  C K F   S L+ H +IHTG+K ++C+ C K F     L RH+  H+   P+KC 
Sbjct: 574  YKCEECGKAFNHSSSLSTHKIIHTGEKSYKCEECGKAFLWSSTLRRHKRIHTGEKPYKCE 633

Query: 85   ICQRHFKNLKTFVKHQQLHNETYQNNVKQVRRLLEAKQEKSMYGVYNTFTTEERWALHPC 144
             C + F +     KH+++H        K+  +        + + +  T T E+ +    C
Sbjct: 634  ECGKAFSHSSALAKHKRIHTGEKPYKCKECGKAFSNSSTLANHKI--THTEEKPYKCKEC 691

Query: 145  SKSDPMYS-MKRRKNIHA------CTICGKMFPSQSKLDRHVLIHTGQRPFKCVLCTKSF 197
             K+    S + + K IHA      C  CGK F   S L  H  IHTG++P+KC  C K+F
Sbjct: 692  DKTFKRLSTLTKHKIIHAGEKLYKCEECGKAFNRSSNLTIHKFIHTGEKPYKCEECGKAF 751

Query: 198  RQSTHLKIHQLTHSEERPFQCCFCQKGFKIQSKLLKHKQIHTRNKAFRALLLKKRRTESR 257
              S+ L  H+  H+ E+PF+C  C K F   S L +HK+IHT  K ++     K  + S 
Sbjct: 752  NWSSSLTKHKRIHTREKPFKCKECGKAFIWSSTLTRHKRIHTGEKPYKCEECGKAFSRSS 811

Query: 258  PLPNKLNANQGGFENGEIGESEENNPLDVHSIYIVPFQCPKCEKCFESEQILNEHSCFAA 317
             L      + G                        P++C +C K F+    L +H    A
Sbjct: 812  TLTKHKTIHTGE----------------------KPYKCKECGKAFKHSSALAKHKIIHA 849

Query: 318  -----RSGKIPSRFKRSYNYKTIVKKILAKLKRARSKKLD-------NFQSEKKVFKKSF 365
                 +  +    F +S N  T  K I  K K ++S++ D            K++  +  
Sbjct: 850  GEKLYKCEECGKAFNQSSNL-TTHKIIHTKEKPSKSEECDKAFIWSSTLTEHKRIHTREK 908

Query: 366  LRNCDLISGEQSSEQTQRTFVGSLGKHGTYKTIGNRKKKTLTLPFSWQNMGK--NLKGIL 423
               C+   G+  S+ +  T         T+K +   +K     P+  +  GK  +    L
Sbjct: 909  TYKCE-ECGKAFSQPSHLT---------THKRMHTGEK-----PYKCEECGKAFSQSSTL 953

Query: 424  TTENILSIDNSVNKKDLSICGSSGEEFFNNCEVLQCGFSVPRENIRTRHKIC-------P 476
            TT  I+                +GE+ +  CE  +CG +  + +  T HKI         
Sbjct: 954  TTHKII---------------HTGEKPY-KCE--ECGKAFRKSSTLTEHKIIHTGEKPYK 995

Query: 477  CDKCEKVFPSISKLKRHYLIHTGQRPFGCNICGKSFRQSAHLKRHEQTHNEKSPY-ASLC 535
            C++C K F   S L RH  +HTG++P+ C  CGK+F +S+ L  H+  H  + PY    C
Sbjct: 996  CEECGKAFSQSSTLTRHTRMHTGEKPYKCEECGKAFNRSSKLTTHKIIHTGEKPYKCEEC 1055

Query: 536  QVEFGNFNNLSNHSGNNVNYNASQQCQAPGVQKYEVSESDQMSGVKAESQDFIPGSTGQP 595
               F + + L+ H   +       +C+  G      S+S  ++  K          TG+ 
Sbjct: 1056 GKAFISSSTLNGHKRIHTR-EKPYKCEECG---KAFSQSSTLTRHKRL-------HTGE- 1103

Query: 596  CLPNVLLESEQSNPFCSYSEHQEKNDVFLYRCSVCAKSFRSPSKLERHYLIHAGQKPFEC 655
                         P+               +C  C K+F+  S L +H +IH G+KP++C
Sbjct: 1104 ------------KPY---------------KCGECGKAFKESSALTKHKIIHTGEKPYKC 1136

Query: 656  SVCGKTFRQAPHWKRHQLTH 675
              CGK F Q+     H+  H
Sbjct: 1137 EKCGKAFNQSSILTNHKKIH 1156



 Score =  219 bits (559), Expect = 5e-57
 Identities = 176/704 (25%), Positives = 298/704 (42%), Gaps = 109/704 (15%)

Query: 11  KIQQCVVANKLPRNRPYVCNICFKHFETPSKLARHYLIHTGQKPFECDVCHKTFRQLVHL 70
           K+ QC+      +++ + C    K F       RH + HTG+K F+C  C K+F   +H 
Sbjct: 141 KLNQCLTT---AQSKVFQCGKYLKVFYKFLNSNRHTIRHTGKKCFKCKKCVKSFCIRLHK 197

Query: 71  ERHQLTH--SLPFKCSICQRHFKNLKTFVKHQQLHNETYQNNVKQVRRLLEAKQEKSMYG 128
            +H+  +      KC  C++ F    T   H+++H E      ++  +   A ++ S   
Sbjct: 198 TQHKCVYITEKSCKCKECEKTFHWSSTLTNHKEIHTEDKPYKCEECGK---AFKQLSTLT 254

Query: 129 VYNTFTTEERWALHPCSKSDPMY----SMKRRKNIHA------CTICGKMFPSQSKLDRH 178
            +     +E+  ++ C +    +    ++ R K IH       C  CGK F   S L +H
Sbjct: 255 THKIICAKEK--IYKCEECGKAFLWSSTLTRHKRIHTGEKPYKCEECGKAFSHSSTLAKH 312

Query: 179 VLIHTGQRPFKCVLCTKSFRQSTHLKIHQLTHSEERPFQCCFCQKGFKIQSKLLKHKQIH 238
             IHTG++P+KC  C K+F +S+ L  H+  H+ E+P++C  C K F   S L  HK  H
Sbjct: 313 KRIHTGEKPYKCEECGKAFSRSSTLAKHKRIHTGEKPYKCKECGKAFSNSSTLANHKITH 372

Query: 239 TRNKAFRALLLKK--RRTESRPLPNKLNANQGGFENGEIGES-EENNPLDVHSIYIV--- 292
           T  K ++     K  +R  +      ++A +  ++  E G++   ++ L +H        
Sbjct: 373 TEEKPYKCKECDKAFKRLSTLTKHKIIHAGEKLYKCEECGKAFNRSSNLTIHKFIHTGEK 432

Query: 293 PFQCPKCEKCFESEQILNEHSCFAARSGKIPSRFKRSYNYKTIVKKILAKLKRARSKKLD 352
           P++C +C K F     L +H  F  R        ++ +  K   K  +      R K++ 
Sbjct: 433 PYKCEECGKAFNWSSSLTKHKRFHTR--------EKPFKCKECGKAFIWSSTLTRHKRIH 484

Query: 353 NFQSEKKVFK--KSFLRNCDLISGEQSSEQTQRTFVGSLGKHGTYKTIGNRKKKTLTL-- 408
             +   K  +  K+F          QSS  T+   + +  K   ++  G   +++LTL  
Sbjct: 485 TGEKPYKCEECGKAF---------RQSSTLTKHKIIHTGEKPYKFEECGKAFRQSLTLNK 535

Query: 409 ---------PFSWQNMGKNLK--GILTTENILSIDNSVNKKDLSICGSSGEEFFNNCEVL 457
                    P+  +  GK  K    LTT  I+     + K     C   G+ F ++  + 
Sbjct: 536 HKIIHSREKPYKCKECGKAFKQFSTLTTHKIIHAGKKLYK-----CEECGKAFNHSSSL- 589

Query: 458 QCGFSVPRENIRTRHKICPCDKCEKVFPSISKLKRHYLIHTGQRPFGCNICGKSFRQSAH 517
                   + I T  K   C++C K F   S L+RH  IHTG++P+ C  CGK+F  S+ 
Sbjct: 590 -----STHKIIHTGEKSYKCEECGKAFLWSSTLRRHKRIHTGEKPYKCEECGKAFSHSSA 644

Query: 518 LKRHEQTHNEKSPY-ASLCQVEFGNFNNLSNHSGNNVNYNASQQCQAPGVQKYEVSESDQ 576
           L +H++ H  + PY    C   F N + L+NH   +              + Y+  E D 
Sbjct: 645 LAKHKRIHTGEKPYKCKECGKAFSNSSTLANHKITHTE-----------EKPYKCKECD- 692

Query: 577 MSGVKAESQDFIPGSTGQPCLPNVLLESEQSNPFCSYSEHQEKNDVFLYRCSVCAKSFRS 636
                   + F   ST      + ++ + +                 LY+C  C K+F  
Sbjct: 693 --------KTFKRLST---LTKHKIIHAGEK----------------LYKCEECGKAFNR 725

Query: 637 PSKLERHYLIHAGQKPFECSVCGKTFRQAPHWKRHQLTHFKERP 680
            S L  H  IH G+KP++C  CGK F  +    +H+  H +E+P
Sbjct: 726 SSNLTIHKFIHTGEKPYKCEECGKAFNWSSSLTKHKRIHTREKP 769



 Score =  157 bits (396), Expect = 4e-38
 Identities = 93/305 (30%), Positives = 150/305 (49%), Gaps = 17/305 (5%)

Query: 23   RNRPYVCNICFKHFETPSKLARHYLIHTGQKPFECDVCHKTFRQLVHLERHQLTHS--LP 80
            R +P+ C  C K F   S L RH  IHTG+KP++C+ C K F +   L +H+  H+   P
Sbjct: 766  REKPFKCKECGKAFIWSSTLTRHKRIHTGEKPYKCEECGKAFSRSSTLTKHKTIHTGEKP 825

Query: 81   FKCSICQRHFKNLKTFVKHQQLHNETYQNNVKQVRRLLEAKQEKSMYGVYNTFTTEERWA 140
            +KC  C + FK+     KH+ +H        ++  +        + + + +  T E+   
Sbjct: 826  YKCKECGKAFKHSSALAKHKIIHAGEKLYKCEECGKAFNQSSNLTTHKIIH--TKEKPSK 883

Query: 141  LHPCSK----SDPMYSMKR---RKNIHACTICGKMFPSQSKLDRHVLIHTGQRPFKCVLC 193
               C K    S  +   KR   R+  + C  CGK F   S L  H  +HTG++P+KC  C
Sbjct: 884  SEECDKAFIWSSTLTEHKRIHTREKTYKCEECGKAFSQPSHLTTHKRMHTGEKPYKCEEC 943

Query: 194  TKSFRQSTHLKIHQLTHSEERPFQCCFCQKGFKIQSKLLKHKQIHTRNKAFRALLLKKRR 253
             K+F QS+ L  H++ H+ E+P++C  C K F+  S L +HK IHT  K ++     K  
Sbjct: 944  GKAFSQSSTLTTHKIIHTGEKPYKCEECGKAFRKSSTLTEHKIIHTGEKPYKCEECGKAF 1003

Query: 254  TESRPLP--NKLNANQGGFENGEIGES-EENNPLDVHSIYIV---PFQCPKCEKCFESEQ 307
            ++S  L    +++  +  ++  E G++   ++ L  H I      P++C +C K F S  
Sbjct: 1004 SQSSTLTRHTRMHTGEKPYKCEECGKAFNRSSKLTTHKIIHTGEKPYKCEECGKAFISSS 1063

Query: 308  ILNEH 312
             LN H
Sbjct: 1064 TLNGH 1068



 Score =  153 bits (386), Expect = 6e-37
 Identities = 99/329 (30%), Positives = 162/329 (49%), Gaps = 41/329 (12%)

Query: 25   RPYVCNICFKHFETPSKLARHYLIHTGQKPFECDVCHKTFRQLVHLERHQLTHSL--PFK 82
            +PY C  C K F+  S LA+H +IH G+K ++C+ C K F Q  +L  H++ H+   P K
Sbjct: 824  KPYKCKECGKAFKHSSALAKHKIIHAGEKLYKCEECGKAFNQSSNLTTHKIIHTKEKPSK 883

Query: 83   CSICQRHFKNLKTFVKHQQLHN--ETYQ-----------NNVKQVRRL------LEAKQE 123
               C + F    T  +H+++H   +TY+           +++   +R+       + ++ 
Sbjct: 884  SEECDKAFIWSSTLTEHKRIHTREKTYKCEECGKAFSQPSHLTTHKRMHTGEKPYKCEEC 943

Query: 124  KSMYGVYNTFTT-------EERWALHPCSKSDPMYS-MKRRKNIHA------CTICGKMF 169
               +   +T TT       E+ +    C K+    S +   K IH       C  CGK F
Sbjct: 944  GKAFSQSSTLTTHKIIHTGEKPYKCEECGKAFRKSSTLTEHKIIHTGEKPYKCEECGKAF 1003

Query: 170  PSQSKLDRHVLIHTGQRPFKCVLCTKSFRQSTHLKIHQLTHSEERPFQCCFCQKGFKIQS 229
               S L RH  +HTG++P+KC  C K+F +S+ L  H++ H+ E+P++C  C K F   S
Sbjct: 1004 SQSSTLTRHTRMHTGEKPYKCEECGKAFNRSSKLTTHKIIHTGEKPYKCEECGKAFISSS 1063

Query: 230  KLLKHKQIHTRNKAFRALLLKKRRTESRPLP--NKLNANQGGFENGEIGES-EENNPLDV 286
             L  HK+IHTR K ++     K  ++S  L    +L+  +  ++ GE G++ +E++ L  
Sbjct: 1064 TLNGHKRIHTREKPYKCEECGKAFSQSSTLTRHKRLHTGEKPYKCGECGKAFKESSALTK 1123

Query: 287  HSIYIV---PFQCPKCEKCFESEQILNEH 312
            H I      P++C KC K F    IL  H
Sbjct: 1124 HKIIHTGEKPYKCEKCGKAFNQSSILTNH 1152



 Score =  147 bits (372), Expect = 2e-35
 Identities = 145/613 (23%), Positives = 236/613 (38%), Gaps = 68/613 (11%)

Query: 98  KHQQLHNETYQNNVKQVRRLLEAKQEKSMYGVYNTFTTEERWALHPCSKSDPMYSMKRRK 157
           K+++  +E  Q   K  + + E K  K  Y   N   T  +  +  C K   ++      
Sbjct: 111 KYEKCGHENLQLR-KGCKSVDECKVHKEGYNKLNQCLTTAQSKVFQCGKYLKVFYKFLNS 169

Query: 158 NIHA----------CTICGKMFPSQSKLDRHVLIHTGQRPFKCVLCTKSFRQSTHLKIHQ 207
           N H           C  C K F  +    +H  ++  ++  KC  C K+F  S+ L  H+
Sbjct: 170 NRHTIRHTGKKCFKCKKCVKSFCIRLHKTQHKCVYITEKSCKCKECEKTFHWSSTLTNHK 229

Query: 208 LTHSEERPFQCCFCQKGFKIQSKLLKHKQIHTRNKAFRALLLKKRRTESRPLP--NKLNA 265
             H+E++P++C  C K FK  S L  HK I  + K ++     K    S  L    +++ 
Sbjct: 230 EIHTEDKPYKCEECGKAFKQLSTLTTHKIICAKEKIYKCEECGKAFLWSSTLTRHKRIHT 289

Query: 266 NQGGFENGEIGES-EENNPLDVHSIYIV---PFQCPKCEKCFESEQILNEHSCF------ 315
            +  ++  E G++   ++ L  H        P++C +C K F     L +H         
Sbjct: 290 GEKPYKCEECGKAFSHSSTLAKHKRIHTGEKPYKCEECGKAFSRSSTLAKHKRIHTGEKP 349

Query: 316 --AARSGKIPSRFKRSYNYK---TIVKKILAKLKRARSKKLDNFQSEKKVFKKSFLRNCD 370
                 GK  S      N+K   T  K    K      K+L      K +     L  C+
Sbjct: 350 YKCKECGKAFSNSSTLANHKITHTEEKPYKCKECDKAFKRLSTLTKHKIIHAGEKLYKCE 409

Query: 371 LI--SGEQSSEQTQRTFVGSLGKHGTYKTIGNRKKKTLTLPFSWQNMGKNLKGILTTENI 428
               +  +SS  T   F+ +  K    +  G          F+W +     K   T E  
Sbjct: 410 ECGKAFNRSSNLTIHKFIHTGEKPYKCEECGK--------AFNWSSSLTKHKRFHTREKP 461

Query: 429 LSIDNSVNKKDLSICGSSGEEFFNNCEVLQCGFSVPRENIRTRHKICPCDKCEKVFPSIS 488
                         C   G+ F  +  + +       + I T  K   C++C K F   S
Sbjct: 462 FK------------CKECGKAFIWSSTLTR------HKRIHTGEKPYKCEECGKAFRQSS 503

Query: 489 KLKRHYLIHTGQRPFGCNICGKSFRQSAHLKRHEQTHNEKSPY-ASLCQVEFGNFNNLSN 547
            L +H +IHTG++P+    CGK+FRQS  L +H+  H+ + PY    C   F  F+ L+ 
Sbjct: 504 TLTKHKIIHTGEKPYKFEECGKAFRQSLTLNKHKIIHSREKPYKCKECGKAFKQFSTLTT 563

Query: 548 HSGNNVNYNASQQCQAPGVQKYEVSESDQMSGVKAESQDFIPGSTGQPCLPNVLLESEQS 607
           H   +       +C+  G      S       +    + +     G+  L +  L   + 
Sbjct: 564 HKIIHAG-KKLYKCEECGKAFNHSSSLSTHKIIHTGEKSYKCEECGKAFLWSSTLRRHKR 622

Query: 608 NPFCSYSEHQEKNDVFLYRCSVCAKSFRSPSKLERHYLIHAGQKPFECSVCGKTFRQAPH 667
                     EK     Y+C  C K+F   S L +H  IH G+KP++C  CGK F  +  
Sbjct: 623 ------IHTGEKP----YKCEECGKAFSHSSALAKHKRIHTGEKPYKCKECGKAFSNSST 672

Query: 668 WKRHQLTHFKERP 680
              H++TH +E+P
Sbjct: 673 LANHKITHTEEKP 685



 Score =  145 bits (365), Expect = 2e-34
 Identities = 74/224 (33%), Positives = 117/224 (52%), Gaps = 11/224 (4%)

Query: 25   RPYVCNICFKHFETPSKLARHYLIHTGQKPFECDVCHKTFRQLVHLERHQLTHS--LPFK 82
            +PY C  C K F   S L  H +IHTG+KP++C+ C K FR+   L  H++ H+   P+K
Sbjct: 936  KPYKCEECGKAFSQSSTLTTHKIIHTGEKPYKCEECGKAFRKSSTLTEHKIIHTGEKPYK 995

Query: 83   CSICQRHFKNLKTFVKHQQLHNETYQNNVKQVRRLLEAKQEKSMYGVYNTFTTEERWALH 142
            C  C + F    T  +H ++H        ++  +      + + + + +T   E+ +   
Sbjct: 996  CEECGKAFSQSSTLTRHTRMHTGEKPYKCEECGKAFNRSSKLTTHKIIHT--GEKPYKCE 1053

Query: 143  PCSK----SDPMYSMKR---RKNIHACTICGKMFPSQSKLDRHVLIHTGQRPFKCVLCTK 195
             C K    S  +   KR   R+  + C  CGK F   S L RH  +HTG++P+KC  C K
Sbjct: 1054 ECGKAFISSSTLNGHKRIHTREKPYKCEECGKAFSQSSTLTRHKRLHTGEKPYKCGECGK 1113

Query: 196  SFRQSTHLKIHQLTHSEERPFQCCFCQKGFKIQSKLLKHKQIHT 239
            +F++S+ L  H++ H+ E+P++C  C K F   S L  HK+IHT
Sbjct: 1114 AFKESSALTKHKIIHTGEKPYKCEKCGKAFNQSSILTNHKKIHT 1157



 Score = 72.8 bits (177), Expect = 1e-12
 Identities = 31/86 (36%), Positives = 47/86 (54%), Gaps = 2/86 (2%)

Query: 23   RNRPYVCNICFKHFETPSKLARHYLIHTGQKPFECDVCHKTFRQLVHLERHQLTHS--LP 80
            R +PY C  C K F   S L RH  +HTG+KP++C  C K F++   L +H++ H+   P
Sbjct: 1074 REKPYKCEECGKAFSQSSTLTRHKRLHTGEKPYKCGECGKAFKESSALTKHKIIHTGEKP 1133

Query: 81   FKCSICQRHFKNLKTFVKHQQLHNET 106
            +KC  C + F        H+++H  T
Sbjct: 1134 YKCEKCGKAFNQSSILTNHKKIHTIT 1159


>gi|210031219 zinc finger protein 845 [Homo sapiens]
          Length = 970

 Score =  226 bits (577), Expect = 4e-59
 Identities = 179/699 (25%), Positives = 300/699 (42%), Gaps = 106/699 (15%)

Query: 25  RPYVCNICFKHFETPSKLARHYLIHTGQKPFECDVCHKTFRQLVHLERHQLTHS--LPFK 82
           + Y CN C K F   S L  H  +HTG+KP++C+ C K F    +LERH+  H+   P+K
Sbjct: 325 KSYKCNECGKTFSQTSYLVYHRRLHTGEKPYKCEECDKAFSFKSNLERHRKIHTGEKPYK 384

Query: 83  CSICQRHFKNLKTFVKHQQLHNETYQNNVKQVRRLLEAKQEKSMYGVYNTFTTEERWALH 142
           C+ C R F    +  +H++LH                              T E+ +  +
Sbjct: 385 CNECSRTFSRKSSLTRHRRLH------------------------------TGEKPYKCN 414

Query: 143 PCSKS-DPMYSMKRRKNIHA------CTICGKMFPSQSKLDRHVLIHTGQRPFKCVLCTK 195
            C K+   M S+   + +H       C  C + F  +S L+RH  IHTG++P+KC  C K
Sbjct: 415 DCGKTFSQMSSLVYHRRLHTGEKPYKCEECDEAFSFKSNLERHRRIHTGEKPYKCNDCGK 474

Query: 196 SFRQSTHLKIHQLTHSEERPFQCCFCQKGFKIQSKLLKHKQIHTRNKAFRALLLKKRRTE 255
           +F Q++ L  H+  H+ E+P++C  C + F  +S L +H+ IHT  K ++     K  + 
Sbjct: 475 TFSQTSSLVYHRRLHTGEKPYKCEECDEAFSFKSNLERHRIIHTGEKLYKCNECGKTFSR 534

Query: 256 SRPLPN--KLNANQGGFENGEIGESEENNPL-----DVHSIYIVPFQCPKCEKCFESEQI 308
              L    +L+  +  ++  E G++            +H I  + ++C  C + F +   
Sbjct: 535 KSSLTRHCRLHTGEKPYQCNECGKAFRGQSALIYHQAIHGIGKL-YKCNDCHQVFSNATT 593

Query: 309 LNEH--------SCFAARSGKIPSRFKRSYNYKTIVKKILAKLKRARSKKLDNFQSEKKV 360
           +  H        S    R GK    F R  +Y  +  +  +  K  + ++ D   S    
Sbjct: 594 IANHWRIHNEERSYKCNRCGK----FFRHRSYLAVHWRTHSGEKPYKCEECDEAFS---- 645

Query: 361 FKKSFLRNCDLISGEQSSEQTQRTFVGSLGKHGTYKTIGNRKKKTLTLPFSWQNMGKNLK 420
           FK +  R+  + +GE+     +    G      +Y T  +R+  T   P+     GK   
Sbjct: 646 FKSNLQRHRRIHTGEKPYRCNE---CGKTFSRKSYLTC-HRRLHTGEKPYKCNECGKTFG 701

Query: 421 GILTTENILSIDNSVNKKDLSI-CGSSGEEFFNNCEVLQCGFSVPRENIRTRHKICPCDK 479
                 + L I  +++  +    C   G+ F      L C        + T  K   C++
Sbjct: 702 ----RNSALIIHKAIHTGEKPYKCNECGKAFSQKSS-LTCHL-----RLHTGEKPYKCEE 751

Query: 480 CEKVFPSISKLKRHYLIHTGQRPFGCNICGKSFRQSAHLKRHEQTHNEKSPYASLCQVEF 539
           C+KVF   S L++H  IHTG++P+ C +C K+F + +HL +H + H  + PY   C    
Sbjct: 752 CDKVFSRKSSLEKHRRIHTGEKPYKCKVCDKAFGRDSHLAQHTRIHTGEKPYK--CNECG 809

Query: 540 GNFNNLS-----------------NHSGNNVNYNASQQCQAP---GVQKYEVSESDQMSG 579
            NF + S                 N  G    +N++ +       G + Y+ SE  ++  
Sbjct: 810 KNFRHNSALVIHKAIHSGEKPYKCNECGKTFRHNSALEIHKAIHTGEKPYKCSECGKVFN 869

Query: 580 VKAESQDFIPGSTGQP---CLPNVLLESEQSNPFCSYSEHQEKNDVFLYRCSVCAKSFRS 636
            KA         TG+    C     + ++Q++  C +  H  +     Y+C+ C K+FR 
Sbjct: 870 RKANLSRHHRLHTGEKPYKCNKCGKVFNQQAHLACHHRIHTGEKP---YKCNECGKTFRH 926

Query: 637 PSKLERHYLIHAGQKPFECSVCGKTFRQAPHWKRHQLTH 675
            S L  H  IH G+KP++C+ CGK F +     RH   H
Sbjct: 927 NSVLVIHKTIHTGEKPYKCNECGKVFNRKAKLARHHRIH 965



 Score =  214 bits (545), Expect = 2e-55
 Identities = 178/698 (25%), Positives = 290/698 (41%), Gaps = 90/698 (12%)

Query: 23  RNRPYVCNICFKHFETPSKLARHYLIHTGQKPFECDVCHKTFRQLVHLERHQLTHS--LP 80
           R + + CN   K F   S L +H +IH G K ++CDVC K F Q  +L  H+  H+   P
Sbjct: 211 REKSFQCNESGKAFNYSSVLRKHQIIHLGAKQYKCDVCGKVFNQKRYLACHRRCHTGKKP 270

Query: 81  FKCSICQRHFKNLKTFVKHQQLHNETYQNNVKQVRRLLEAKQEKSMYGVYNTFTTEERWA 140
           +KC+ C + F    T   H +LH         +  +         ++   +T   E+ + 
Sbjct: 271 YKCNDCGKTFSQELTLTCHHRLHTGEKHYKCSECGKTFSRNSALVIHKAIHT--GEKSYK 328

Query: 141 LHPCSK--SDPMYSMKRRK-----NIHACTICGKMFPSQSKLDRHVLIHTGQRPFKCVLC 193
            + C K  S   Y +  R+       + C  C K F  +S L+RH  IHTG++P+KC  C
Sbjct: 329 CNECGKTFSQTSYLVYHRRLHTGEKPYKCEECDKAFSFKSNLERHRKIHTGEKPYKCNEC 388

Query: 194 TKSFRQSTHLKIHQLTHSEERPFQCCFCQKGFKIQSKLLKHKQIHTRNKAFRALLLKKRR 253
           +++F + + L  H+  H+ E+P++C  C K F   S L+ H+++HT  K ++        
Sbjct: 389 SRTFSRKSSLTRHRRLHTGEKPYKCNDCGKTFSQMSSLVYHRRLHTGEKPYKC------- 441

Query: 254 TESRPLPNKLNANQGGFENGEIGESEENNPLDVHSIYIVPFQCPKCEKCFESEQILNEHS 313
            E         +N         GE               P++C  C K F     L  H 
Sbjct: 442 -EECDEAFSFKSNLERHRRIHTGEK--------------PYKCNDCGKTFSQTSSLVYHR 486

Query: 314 CFAARSGKIPSRFKR---SYNYKTIVKKILAKLKRAR----SKKLDNFQSEKKVF--KKS 364
                +G+ P + +    ++++K+        L+R R     +KL       K F  K S
Sbjct: 487 --RLHTGEKPYKCEECDEAFSFKS-------NLERHRIIHTGEKLYKCNECGKTFSRKSS 537

Query: 365 FLRNCDLISGEQSSEQTQ--RTFVG--SLGKHGTYKTIGNRKKKTLTLPFSWQNMGKNLK 420
             R+C L +GE+  +  +  + F G  +L  H     IG   K          +  +   
Sbjct: 538 LTRHCRLHTGEKPYQCNECGKAFRGQSALIYHQAIHGIGKLYK--------CNDCHQVFS 589

Query: 421 GILTTENILSIDNSVNKKDLSICGSSGEEFFNNCEVLQCGFSVPRENIRTRHKICPCDKC 480
              T  N   I N       + CG    +FF +   L   +        +  K   C++C
Sbjct: 590 NATTIANHWRIHNEERSYKCNRCG----KFFRHRSYLAVHWRT-----HSGEKPYKCEEC 640

Query: 481 EKVFPSISKLKRHYLIHTGQRPFGCNICGKSFRQSAHLKRHEQTHNEKSPY-ASLCQVEF 539
           ++ F   S L+RH  IHTG++P+ CN CGK+F + ++L  H + H  + PY  + C   F
Sbjct: 641 DEAFSFKSNLQRHRRIHTGEKPYRCNECGKTFSRKSYLTCHRRLHTGEKPYKCNECGKTF 700

Query: 540 GNFNNL--------------SNHSGNNVNYNASQQCQA---PGVQKYEVSESDQMSGVKA 582
           G  + L               N  G   +  +S  C      G + Y+  E D++   K+
Sbjct: 701 GRNSALIIHKAIHTGEKPYKCNECGKAFSQKSSLTCHLRLHTGEKPYKCEECDKVFSRKS 760

Query: 583 ESQDFIPGSTGQPCLPNVLLESEQSNPFCSYSEHQEKNDVFLYRCSVCAKSFRSPSKLER 642
             +      TG+      + +             +       Y+C+ C K+FR  S L  
Sbjct: 761 SLEKHRRIHTGEKPYKCKVCDKAFGRDSHLAQHTRIHTGEKPYKCNECGKNFRHNSALVI 820

Query: 643 HYLIHAGQKPFECSVCGKTFRQAPHWKRHQLTHFKERP 680
           H  IH+G+KP++C+ CGKTFR     + H+  H  E+P
Sbjct: 821 HKAIHSGEKPYKCNECGKTFRHNSALEIHKAIHTGEKP 858



 Score =  179 bits (454), Expect = 8e-45
 Identities = 140/514 (27%), Positives = 212/514 (41%), Gaps = 80/514 (15%)

Query: 27  YVCNICFKHFETPSKLARHYLIHTGQKPFECDVCHKTFRQLVHLERHQLTHSLP--FKCS 84
           Y CN C K F   S L RH  +HTG+KP++C+ C K FR    L  HQ  H +   +KC+
Sbjct: 523 YKCNECGKTFSRKSSLTRHCRLHTGEKPYQCNECGKAFRGQSALIYHQAIHGIGKLYKCN 582

Query: 85  ICQRHFKNLKTFVKHQQLHNETYQNNVKQVRRLLEAKQEKSMYGVYNTFTTEERWALHPC 144
            C + F N  T   H ++HNE       +  +    +   +++           W  H  
Sbjct: 583 DCHQVFSNATTIANHWRIHNEERSYKCNRCGKFFRHRSYLAVH-----------WRTHSG 631

Query: 145 SKSDPMYSMKRRKNIHACTICGKMFPSQSKLDRHVLIHTGQRPFKCVLCTKSFRQSTHLK 204
            K             + C  C + F  +S L RH  IHTG++P++C  C K+F + ++L 
Sbjct: 632 EKP------------YKCEECDEAFSFKSNLQRHRRIHTGEKPYRCNECGKTFSRKSYLT 679

Query: 205 IHQLTHSEERPFQCCFCQKGFKIQSKLLKHKQIHTRNKAFRALLLKKRRTESRPLPNKLN 264
            H+  H+ E+P++C  C K F   S L+ HK IHT  K ++     K  ++   L   L 
Sbjct: 680 CHRRLHTGEKPYKCNECGKTFGRNSALIIHKAIHTGEKPYKCNECGKAFSQKSSLTCHLR 739

Query: 265 ANQGGFENGEIGESEENNPLDVHSIYIVPFQCPKCEKCFESEQILNEHSCFAARSGKIPS 324
            + G                        P++C +C+K F  +  L +H      +G+ P 
Sbjct: 740 LHTGE----------------------KPYKCEECDKVFSRKSSLEKHR--RIHTGEKP- 774

Query: 325 RFKRSYNYKTIVKKILAKLKRARSKKLDNFQSEKKVFK--KSFLRNCDLI------SGEQ 376
                Y  K   K        A+  ++   +   K  +  K+F  N  L+      SGE+
Sbjct: 775 -----YKCKVCDKAFGRDSHLAQHTRIHTGEKPYKCNECGKNFRHNSALVIHKAIHSGEK 829

Query: 377 SSEQTQRTFVGSLGKHGTYKTIGNRKKKTLTLPFSWQNMGK--NLKGILTTENILSIDNS 434
             +  +    G   +H +   I ++   T   P+     GK  N K  L+  + L     
Sbjct: 830 PYKCNE---CGKTFRHNSALEI-HKAIHTGEKPYKCSECGKVFNRKANLSRHHRLHTGEK 885

Query: 435 VNKKDLSICGSSGEEFFNNCEVLQCGFSVPRENIRTRHKICPCDKCEKVFPSISKLKRHY 494
             K     C   G+  FN    L C        I T  K   C++C K F   S L  H 
Sbjct: 886 PYK-----CNKCGK-VFNQQAHLAC-----HHRIHTGEKPYKCNECGKTFRHNSVLVIHK 934

Query: 495 LIHTGQRPFGCNICGKSFRQSAHLKRHEQTHNEK 528
            IHTG++P+ CN CGK F + A L RH + H  K
Sbjct: 935 TIHTGEKPYKCNECGKVFNRKAKLARHHRIHTGK 968



 Score =  141 bits (355), Expect = 2e-33
 Identities = 76/230 (33%), Positives = 122/230 (53%), Gaps = 17/230 (7%)

Query: 25  RPYVCNICFKHFETPSKLARHYLIHTGQKPFECDVCHKTFRQLVHLERHQLTHS--LPFK 82
           +PY C  C K F   S L +H  IHTG+KP++C VC K F +  HL +H   H+   P+K
Sbjct: 745 KPYKCEECDKVFSRKSSLEKHRRIHTGEKPYKCKVCDKAFGRDSHLAQHTRIHTGEKPYK 804

Query: 83  CSICQRHFKNLKTFVKHQQLHNETYQNNVKQVRRLLEAKQEKSMYGVYNTFTTEERWALH 142
           C+ C ++F++    V H+ +H+        +  +     +  S   ++    T E+   +
Sbjct: 805 CNECGKNFRHNSALVIHKAIHSGEKPYKCNECGKTF---RHNSALEIHKAIHTGEK--PY 859

Query: 143 PCSKSDPMYSMK----RRKNIHA------CTICGKMFPSQSKLDRHVLIHTGQRPFKCVL 192
            CS+   +++ K    R   +H       C  CGK+F  Q+ L  H  IHTG++P+KC  
Sbjct: 860 KCSECGKVFNRKANLSRHHRLHTGEKPYKCNKCGKVFNQQAHLACHHRIHTGEKPYKCNE 919

Query: 193 CTKSFRQSTHLKIHQLTHSEERPFQCCFCQKGFKIQSKLLKHKQIHTRNK 242
           C K+FR ++ L IH+  H+ E+P++C  C K F  ++KL +H +IHT  K
Sbjct: 920 CGKTFRHNSVLVIHKTIHTGEKPYKCNECGKVFNRKAKLARHHRIHTGKK 969



 Score =  132 bits (331), Expect = 1e-30
 Identities = 139/580 (23%), Positives = 229/580 (39%), Gaps = 71/580 (12%)

Query: 156 RKNIHACTICGKMFPSQSKLDRHVLIHTGQRPFKCVLCTKSFRQSTHLKIHQLTHSEERP 215
           R   H     G  F + S L +   +H  ++ F+C    K+F  S+ L+ HQ+ H   + 
Sbjct: 183 RPKTHISKNYGNNFLNSSLLTQKQEVHMREKSFQCNESGKAFNYSSVLRKHQIIHLGAKQ 242

Query: 216 FQCCFCQKGFKIQSKLLKHKQIHTRNKAFRALLLKKRRTESRPLP--NKLNANQGGFENG 273
           ++C  C K F  +  L  H++ HT  K ++     K  ++   L   ++L+  +  ++  
Sbjct: 243 YKCDVCGKVFNQKRYLACHRRCHTGKKPYKCNDCGKTFSQELTLTCHHRLHTGEKHYKCS 302

Query: 274 EIGES-EENNPLDVHSIYIV---PFQCPKCEKCFESEQILNEHSCFAARSGKIPSRFK-- 327
           E G++   N+ L +H         ++C +C K F     L  H      +G+ P + +  
Sbjct: 303 ECGKTFSRNSALVIHKAIHTGEKSYKCNECGKTFSQTSYLVYHR--RLHTGEKPYKCEEC 360

Query: 328 -RSYNYKTIVKKILAKLKRARSKKLDNFQSEKKVFKKSFLRNCDLISGEQ--SSEQTQRT 384
            +++++K+ +++   K+         N  S     K S  R+  L +GE+        +T
Sbjct: 361 DKAFSFKSNLER-HRKIHTGEKPYKCNECSRTFSRKSSLTRHRRLHTGEKPYKCNDCGKT 419

Query: 385 F--VGSLGKHGTYKTIGNRKKKTLTLPFSWQNMGKNLKGILTTENILSIDNSVNKKDLSI 442
           F  + SL  H        R+  T   P+  +   +        E    I         + 
Sbjct: 420 FSQMSSLVYH--------RRLHTGEKPYKCEECDEAFSFKSNLERHRRIHTGEKPYKCND 471

Query: 443 CGS---------------SGEEFFNNCEVLQCGFSVP-----RENIRTRHKICPCDKCEK 482
           CG                +GE+ +  CE     FS          I T  K+  C++C K
Sbjct: 472 CGKTFSQTSSLVYHRRLHTGEKPY-KCEECDEAFSFKSNLERHRIIHTGEKLYKCNECGK 530

Query: 483 VFPSISKLKRHYLIHTGQRPFGCNICGKSFRQSAHLKRHEQTHNEKSPY-ASLCQVEFGN 541
            F   S L RH  +HTG++P+ CN CGK+FR  + L  H+  H     Y  + C   F N
Sbjct: 531 TFSRKSSLTRHCRLHTGEKPYQCNECGKAFRGQSALIYHQAIHGIGKLYKCNDCHQVFSN 590

Query: 542 FNNLSNHSGNNVNYNASQQCQA------------------PGVQKYEVSESDQMSGVKAE 583
              ++NH   + N   S +C                     G + Y+  E D+    K+ 
Sbjct: 591 ATTIANHWRIH-NEERSYKCNRCGKFFRHRSYLAVHWRTHSGEKPYKCEECDEAFSFKSN 649

Query: 584 SQDFIPGSTGQP---CLPNVLLESEQSNPFCSYSEHQEKNDVFLYRCSVCAKSFRSPSKL 640
            Q      TG+    C       S +S   C    H  +     Y+C+ C K+F   S L
Sbjct: 650 LQRHRRIHTGEKPYRCNECGKTFSRKSYLTCHRRLHTGEKP---YKCNECGKTFGRNSAL 706

Query: 641 ERHYLIHAGQKPFECSVCGKTFRQAPHWKRHQLTHFKERP 680
             H  IH G+KP++C+ CGK F Q      H   H  E+P
Sbjct: 707 IIHKAIHTGEKPYKCNECGKAFSQKSSLTCHLRLHTGEKP 746


>gi|172072608 zinc finger protein 624 [Homo sapiens]
          Length = 865

 Score =  222 bits (566), Expect = 8e-58
 Identities = 179/675 (26%), Positives = 292/675 (43%), Gaps = 104/675 (15%)

Query: 23  RNRPYVCNICFKHFETPSKLARHYLIHTGQKPFECDVCHKTFRQLVHLERHQLTHS--LP 80
           + +PY C+ C K F   S L +H   HT +KP+EC+ C KTF Q  +L +H+  H+   P
Sbjct: 272 KEKPYKCSTCEKAFHYRSLLIQHQRTHTKEKPYECNECGKTFSQPSYLSQHKKIHTGEKP 331

Query: 81  FKCSICQRHFKNLKTFVKHQQLH--NETYQNNVKQVRRLLEAKQEKSMYGVYNTFTTEER 138
           +KC+ C + F    + + HQ++H   + YQ NV                           
Sbjct: 332 YKCNECGKAFIASSSLMVHQRIHTKEKPYQCNVCGK------------------------ 367

Query: 139 WALHPCSKSDPMYSMKRRKNIHACTICGKMFPSQSKLDRHVLIHTGQRPFKCVLCTKSFR 198
            +   C++ +    ++  +  + C+ CGK F  +SKL RH   H G++P+KC  C K+FR
Sbjct: 368 -SFSQCARLNQHQRIQTGEKPYKCSECGKAFSDKSKLARHQETHNGEKPYKCDDCGKAFR 426

Query: 199 QSTHLKIHQLTHSEERPFQCCFCQKGFKIQSKLLKHKQIHTRNKAFRALLLKK--RRTES 256
             ++L +HQ TH+EE+P+QC  C K FK  +    H++IHT  K FR     K  R   S
Sbjct: 427 NKSYLSVHQKTHTEEKPYQCNECGKSFKNTTIFNVHQRIHTGEKPFRCNECGKAYRSNSS 486

Query: 257 RPLPNKLNANQGGFENGEIGESEEN--NPLDVHSIYI--VPFQCPKCEKCFESEQILNEH 312
             +  + +  +  +E  E G++     N  +   I+    P++C +C K F +   L  H
Sbjct: 487 LIVHIRTHTGEKPYECNECGKAFNRIANFTEHQRIHTGEKPYKCNECGKAFINYSCLTVH 546

Query: 313 SCFAARSGKIPSRFKRSYNYKTIVKK----ILAKLKRARSKKLDNFQSEKKVFKKSFLRN 368
                 +G+ P  +K +   K  ++     I  ++       L N   E    K     +
Sbjct: 547 --HRMHTGEKP--YKCTECGKAFMRSSSLIIHQRIHTEEKPYLCNECGESFRIKSHLTVH 602

Query: 369 CDLISGEQSSEQT--QRTF--VGSLGKHGTYKTIGNRKKKTLTLPFSWQNMGKNLKGILT 424
             + +GE+  + T  +R F  + +L +H        +K  T   P+   + GK+ +    
Sbjct: 603 QRIHTGEKPYKCTDCERAFTKMVNLKEH--------QKIHTGVKPYKCYDCGKSFR---- 650

Query: 425 TENILSIDNSVNKKDLSICGSSGEEFFNNCEVLQCGFSVPRENIRTRHKICPCDKCEKVF 484
           T++ L +    +  +     +  E+ F N   L        +   T  K   C++C KVF
Sbjct: 651 TKSYLIVHQRTHTGEKPYKCNECEKAFTNTSQL-----TVHQRRHTGEKPYKCNECGKVF 705

Query: 485 PSISKLKRHYLIHTGQRPFGCNICGKSFRQSAHLKRHEQTHNEKSPY-ASLCQVEFGNFN 543
            S S    H   HTG++PF CN CGK+F Q  H+  H++ H+ + PY   +C   F   +
Sbjct: 706 TSNSGFNTHQRTHTGEKPFKCNDCGKAFSQMVHVTEHQKIHSGEKPYKCDVCGKAFRRGS 765

Query: 544 NLSNHSGNNVNYNASQQCQAPGVQKYEVSESDQMSGVKAESQDFIPGSTGQPCLPNVLLE 603
            L+ H   +            G + Y   E                   G+ C+    L 
Sbjct: 766 YLTVHWRTHT-----------GEKPYTCKE------------------CGKGCITLSQLT 796

Query: 604 SEQSNPFCSYSEHQEKNDVFLYRCSVCAKSFRSPSKLERHYLIHAGQKPFECSVCGKTFR 663
             Q         H  +     Y+C  C K+FR+ S    H  +H G+KP++C+ CGK FR
Sbjct: 797 LHQ-------RIHTGERP---YKCEECGKAFRTNSDFTVHLRMHTGEKPYKCNECGKAFR 846

Query: 664 QAPHWKRHQLTHFKE 678
            +     HQ  H +E
Sbjct: 847 SSSSLTVHQRIHQRE 861



 Score =  194 bits (493), Expect = 2e-49
 Identities = 145/549 (26%), Positives = 229/549 (41%), Gaps = 79/549 (14%)

Query: 14  QCVVANKLPR----NRPYVCNICFKHFETPSKLARHYLIHTGQKPFECDVCHKTFRQLVH 69
           QC   N+  R     +PY C+ C K F   SKLARH   H G+KP++CD C K FR   +
Sbjct: 371 QCARLNQHQRIQTGEKPYKCSECGKAFSDKSKLARHQETHNGEKPYKCDDCGKAFRNKSY 430

Query: 70  LERHQLTHS--LPFKCSICQRHFKNLKTFVKHQQLHNETYQNNVKQVRRLLEAKQEKSMY 127
           L  HQ TH+   P++C+ C + FKN   F  HQ++H         +  +    +   S+ 
Sbjct: 431 LSVHQKTHTEEKPYQCNECGKSFKNTTIFNVHQRIHTGEKPFRCNECGKAY--RSNSSLI 488

Query: 128 GVYNTFTTEERWALHPCSKS-DPMYSMKRRKNIHA------CTICGKMFPSQSKLDRHVL 180
               T T E+ +  + C K+ + + +    + IH       C  CGK F + S L  H  
Sbjct: 489 VHIRTHTGEKPYECNECGKAFNRIANFTEHQRIHTGEKPYKCNECGKAFINYSCLTVHHR 548

Query: 181 IHTGQRPFKCVLCTKSFRQSTHLKIHQLTHSEERPFQCCFCQKGFKIQSKLLKHKQIHTR 240
           +HTG++P+KC  C K+F +S+ L IHQ  H+EE+P+ C  C + F+I+S L  H++IHT 
Sbjct: 549 MHTGEKPYKCTECGKAFMRSSSLIIHQRIHTEEKPYLCNECGESFRIKSHLTVHQRIHTG 608

Query: 241 NKAFRALLLKKRRTESRPLPNKLNANQGGFENGEIGESEENNPLDVHSIYIVPFQCPKCE 300
            K ++    ++  T+   L      + G                      + P++C  C 
Sbjct: 609 EKPYKCTDCERAFTKMVNLKEHQKIHTG----------------------VKPYKCYDCG 646

Query: 301 KCFESEQILNEHSCFAARSGKIPSRFKRSYNYKTIVKKILAKLKRARSKKLDNFQSEKKV 360
           K F ++  L  H      +G+ P +        T   ++    +R   +K        KV
Sbjct: 647 KSFRTKSYLIVHQ--RTHTGEKPYKCNECEKAFTNTSQLTVHQRRHTGEKPYKCNECGKV 704

Query: 361 FKKSFLRNCDLISGEQSSEQTQRTFVGSLGKHGTYKTIGNRKKKTLTLPFSWQNMGKNLK 420
           F           +        QRT  G                     PF   + GK   
Sbjct: 705 F-----------TSNSGFNTHQRTHTGE-------------------KPFKCNDCGKAFS 734

Query: 421 GILTTENILSIDNSVNKKDLSICGSSGEEFFNNCEVLQCGFSVPRENIRTRHKICPCDKC 480
            ++       I +        +CG +    F     L   +        T  K   C +C
Sbjct: 735 QMVHVTEHQKIHSGEKPYKCDVCGKA----FRRGSYLTVHW-----RTHTGEKPYTCKEC 785

Query: 481 EKVFPSISKLKRHYLIHTGQRPFGCNICGKSFRQSAHLKRHEQTHNEKSPY-ASLCQVEF 539
            K   ++S+L  H  IHTG+RP+ C  CGK+FR ++    H + H  + PY  + C   F
Sbjct: 786 GKGCITLSQLTLHQRIHTGERPYKCEECGKAFRTNSDFTVHLRMHTGEKPYKCNECGKAF 845

Query: 540 GNFNNLSNH 548
            + ++L+ H
Sbjct: 846 RSSSSLTVH 854



 Score =  181 bits (460), Expect = 2e-45
 Identities = 149/581 (25%), Positives = 248/581 (42%), Gaps = 41/581 (7%)

Query: 111 VKQVRRLLEAKQEKSMYGVYNTFTTEERWALHPCSKSDPMYSMKRRKNIHACTICGKMFP 170
           ++Q   L   K+  +    Y   T E+  A H  S          ++  + C  CGK F 
Sbjct: 257 IRQTSELTLGKKSNNKEKPYKCSTCEK--AFHYRSLLIQHQRTHTKEKPYECNECGKTFS 314

Query: 171 SQSKLDRHVLIHTGQRPFKCVLCTKSFRQSTHLKIHQLTHSEERPFQCCFCQKGFKIQSK 230
             S L +H  IHTG++P+KC  C K+F  S+ L +HQ  H++E+P+QC  C K F   ++
Sbjct: 315 QPSYLSQHKKIHTGEKPYKCNECGKAFIASSSLMVHQRIHTKEKPYQCNVCGKSFSQCAR 374

Query: 231 LLKHKQIHTRNKAFRALLLKKRRTESRPLPNKLNANQGG--FENGEIGESEENNP-LDVH 287
           L +H++I T  K ++     K  ++   L      + G   ++  + G++  N   L VH
Sbjct: 375 LNQHQRIQTGEKPYKCSECGKAFSDKSKLARHQETHNGEKPYKCDDCGKAFRNKSYLSVH 434

Query: 288 SIYIV---PFQCPKCEKCFESEQILNEHSCFAARSGKIPSRFKRSYNYKTIVKKILAKLK 344
                   P+QC +C K F++  I N H      +G+ P R             ++  ++
Sbjct: 435 QKTHTEEKPYQCNECGKSFKNTTIFNVHQ--RIHTGEKPFRCNECGKAYRSNSSLIVHIR 492

Query: 345 RARSKKLDNFQSEKKVFKK--SFLRNCDLISGEQSSEQTQRTFVGSLGKHGTYKTIGNRK 402
               +K        K F +  +F  +  + +GE+  +  +    G    + +  T+ +R 
Sbjct: 493 THTGEKPYECNECGKAFNRIANFTEHQRIHTGEKPYKCNE---CGKAFINYSCLTVHHRM 549

Query: 403 KKTLTLPFSWQNMGKNLKGILTTENILSIDNSVNKKDLSICGSSGEEFFNNCEVLQCGFS 462
             T   P+     GK     + + +++       ++   +C   GE F     +      
Sbjct: 550 H-TGEKPYKCTECGK---AFMRSSSLIIHQRIHTEEKPYLCNECGESFRIKSHL------ 599

Query: 463 VPRENIRTRHKICPCDKCEKVFPSISKLKRHYLIHTGQRPFGCNICGKSFRQSAHLKRHE 522
              + I T  K   C  CE+ F  +  LK H  IHTG +P+ C  CGKSFR  ++L  H+
Sbjct: 600 TVHQRIHTGEKPYKCTDCERAFTKMVNLKEHQKIHTGVKPYKCYDCGKSFRTKSYLIVHQ 659

Query: 523 QTHNEKSPY-ASLCQVEFGNFNNLSNHSGNNVNYNASQQCQAPGVQKYEVSESDQMSGVK 581
           +TH  + PY  + C+  F N + L+ H           Q +  G + Y+ +E  ++    
Sbjct: 660 RTHTGEKPYKCNECEKAFTNTSQLTVH-----------QRRHTGEKPYKCNECGKVFTSN 708

Query: 582 AESQDFIPGSTGQ-PCLPNVLLESEQSNPFCSYSEHQE-KNDVFLYRCSVCAKSFRSPSK 639
           +         TG+ P   N     +  +     +EHQ+  +    Y+C VC K+FR  S 
Sbjct: 709 SGFNTHQRTHTGEKPFKCNDC--GKAFSQMVHVTEHQKIHSGEKPYKCDVCGKAFRRGSY 766

Query: 640 LERHYLIHAGQKPFECSVCGKTFRQAPHWKRHQLTHFKERP 680
           L  H+  H G+KP+ C  CGK          HQ  H  ERP
Sbjct: 767 LTVHWRTHTGEKPYTCKECGKGCITLSQLTLHQRIHTGERP 807



 Score =  106 bits (265), Expect = 6e-23
 Identities = 84/342 (24%), Positives = 151/342 (44%), Gaps = 37/342 (10%)

Query: 363 KSFLRNCDLISGEQSSEQTQRTFVGSLGKHGTYKT--IGNRKKKTLTLPFSWQNMGKNLK 420
           K+  +  +L  G++S+ + +     +  K   Y++  I +++  T   P+     GK   
Sbjct: 255 KAIRQTSELTLGKKSNNKEKPYKCSTCEKAFHYRSLLIQHQRTHTKEKPYECNECGKTF- 313

Query: 421 GILTTENILSIDNSVNKKDLSI-CGSSGEEFFNNCEVLQCGFSVPRENIRTRHKICPCDK 479
              +  + LS    ++  +    C   G+ F  +  ++        + I T+ K   C+ 
Sbjct: 314 ---SQPSYLSQHKKIHTGEKPYKCNECGKAFIASSSLMV------HQRIHTKEKPYQCNV 364

Query: 480 CEKVFPSISKLKRHYLIHTGQRPFGCNICGKSFRQSAHLKRHEQTHNEKSPY-ASLCQVE 538
           C K F   ++L +H  I TG++P+ C+ CGK+F   + L RH++THN + PY    C   
Sbjct: 365 CGKSFSQCARLNQHQRIQTGEKPYKCSECGKAFSDKSKLARHQETHNGEKPYKCDDCGKA 424

Query: 539 FGNFNNLSNHS------------------GNNVNYNASQQCQAPGVQKYEVSESDQMSGV 580
           F N + LS H                    N   +N  Q+    G + +  +E  +    
Sbjct: 425 FRNKSYLSVHQKTHTEEKPYQCNECGKSFKNTTIFNVHQRIHT-GEKPFRCNECGKAYRS 483

Query: 581 KAESQDFIPGSTGQPCLPNVLLESEQS-NPFCSYSEHQE-KNDVFLYRCSVCAKSFRSPS 638
            +     I   TG+   P    E  ++ N   +++EHQ        Y+C+ C K+F + S
Sbjct: 484 NSSLIVHIRTHTGEK--PYECNECGKAFNRIANFTEHQRIHTGEKPYKCNECGKAFINYS 541

Query: 639 KLERHYLIHAGQKPFECSVCGKTFRQAPHWKRHQLTHFKERP 680
            L  H+ +H G+KP++C+ CGK F ++     HQ  H +E+P
Sbjct: 542 CLTVHHRMHTGEKPYKCTECGKAFMRSSSLIIHQRIHTEEKP 583



 Score = 68.2 bits (165), Expect = 2e-11
 Identities = 33/88 (37%), Positives = 48/88 (54%), Gaps = 6/88 (6%)

Query: 25  RPYVCNICFKHFETPSKLARHYLIHTGQKPFECDVCHKTFRQ----LVHLERHQLTHSLP 80
           +PY C  C K   T S+L  H  IHTG++P++C+ C K FR      VHL  H  T   P
Sbjct: 778 KPYTCKECGKGCITLSQLTLHQRIHTGERPYKCEECGKAFRTNSDFTVHLRMH--TGEKP 835

Query: 81  FKCSICQRHFKNLKTFVKHQQLHNETYQ 108
           +KC+ C + F++  +   HQ++H    Q
Sbjct: 836 YKCNECGKAFRSSSSLTVHQRIHQRETQ 863


>gi|156627573 zinc finger protein 836 [Homo sapiens]
          Length = 936

 Score =  222 bits (565), Expect = 1e-57
 Identities = 184/699 (26%), Positives = 284/699 (40%), Gaps = 92/699 (13%)

Query: 23  RNRPYVCNICFKHFETPSKLARHYLIHTGQKPFECDVCHKTFRQLVHLERHQLTHSL--P 80
           R +PY+C  C K F   S L  H ++HT +KP++C+ C K F +   L  HQ+ H+   P
Sbjct: 214 REKPYMCKGCGKAFRVSSSLINHQMVHTTEKPYKCNECGKAFHRGSLLTIHQIVHTRGKP 273

Query: 81  FKCSICQRHFKNLKTFVKHQQLHNETYQNNVKQVRRLLEAKQEKSMYGVYNTFTTEERWA 140
           ++C +C + F+     V H++ H         +  +        +++      T E+ + 
Sbjct: 274 YQCGVCGKIFRQNSDLVNHRRSHTGEKPYKCNECGKSFSQSYNLAIH--QRIHTGEKPYK 331

Query: 141 LHPCSKSDPMYSMKRRKNI-------HACTICGKMFPSQSKLDRHVLIHTGQRPFKCVLC 193
            + C K+    S      I       + C ICGK+F   S L  H  IHTG++P+KC +C
Sbjct: 332 CNECGKTFKQGSCLTTHQIIHTGEKPYQCDICGKVFRQNSNLVNHQRIHTGEKPYKCNIC 391

Query: 194 TKSFRQSTHLKIHQLTHSEERPFQCCFCQKGFKIQSKLLKHKQIHTRNKAFRALLLKKRR 253
            KSF QS++L  HQ  HS  +P++C  C K FK  S L  H+ IHT  K +   +  K  
Sbjct: 392 GKSFSQSSNLATHQTVHSGNKPYKCDECGKTFKRSSSLTTHQIIHTGEKPYTCDVCDKVF 451

Query: 254 TESRPLPNKLNANQGG--FENGEIGE--SEENNPLDVHSIYI--VPFQCPKCEKCFESEQ 307
           ++   L     ++ G   ++  E G+  S+ ++ +    I+    P++C KC K F+   
Sbjct: 452 SQRSQLARHQRSHTGEKPYKCNECGKVFSQTSHLVGHRRIHTGEKPYKCDKCGKAFKQGS 511

Query: 308 ILNEHSCFAARSGKIPSRFKRSYNYKTIVKKILAKLKRARSKKLDNFQSEKKVFKKSFL- 366
           +L  H                             K+   R K+    +  K   + S L 
Sbjct: 512 LLTRH-----------------------------KIIHTREKRYQCGECGKVFSENSCLV 542

Query: 367 RNCDLISGEQ--SSEQTQRTFVGSLGKHGTYKTIGNRKKKTLTLPFSWQNMGKNLKGILT 424
           R+  + +GEQ        + F  S G    +K I   +K     PF     G   +    
Sbjct: 543 RHLRIHTGEQPYKCNVCGKVFNYS-GNLSIHKRIHTGEK-----PFQCNECGTVFRNYSC 596

Query: 425 TENILSIDNSVNKKDLSICGS---------------SGEEFF--NNCEVLQCGFS--VPR 465
               L I         ++CG                +GE+ F  N C  +   +S     
Sbjct: 597 LARHLRIHTGQKPYKCNVCGKVFNDSGNLSNHKRIHTGEKPFQCNECGKVFSYYSCLARH 656

Query: 466 ENIRTRHKICPCDKCEKVFPSISKLKRHYLIHTGQRPFGCNICGKSFRQSAHLKR-HEQT 524
             I T  K   C+ C K +   S L +H +IHTG++P+ CN  G +F QS+ L R H   
Sbjct: 657 RKIHTGEKPYKCNDCGKAYTQRSSLTKHLIIHTGEKPYNCNEFGGAFIQSSKLARYHRNP 716

Query: 525 HNEKSPYASLCQVEFGNFNNLSNHSGNNVNYNASQQCQAPGVQKYEVSESDQM---SGVK 581
             EK    S C   F +   L+ H           Q +  G   Y+  E  Q+   +   
Sbjct: 717 TGEKPHKCSHCGRTFSHITGLTYH-----------QRRHTGEMPYKCIECGQVFNSTSNL 765

Query: 582 AESQDFIPGSTGQPCLPNVLLESEQSNPFCSYSEHQEKNDVFLYRCSVCAKSFRSPSKLE 641
           A  +    G     C     +   QS      S H  +     Y C+ C K+FR  S L 
Sbjct: 766 ARHRRIHTGEKPYKCNECGKVFRHQSTLARHRSIHTGEKP---YVCNECGKAFRVRSILV 822

Query: 642 RHYLIHAGQKPFECSVCGKTFRQAPHWKRHQLTHFKERP 680
            H  +H G KP++C+ CGK F +      HQ  H  E+P
Sbjct: 823 NHQKMHTGDKPYKCNECGKAFIERSKLVYHQRNHTGEKP 861



 Score =  217 bits (552), Expect = 3e-56
 Identities = 184/678 (27%), Positives = 286/678 (42%), Gaps = 114/678 (16%)

Query: 25  RPYVCNICFKHFETPSKLARHYLIHTGQKPFECDVCHKTFRQLVHLERHQLTHS--LPFK 82
           +PY CN C K F+  S L  H +IHTG+KP++CD+C K FRQ  +L  HQ  H+   P+K
Sbjct: 328 KPYKCNECGKTFKQGSCLTTHQIIHTGEKPYQCDICGKVFRQNSNLVNHQRIHTGEKPYK 387

Query: 83  CSICQRHFKNLKTFVKHQQLHNETYQNNVKQVRRLLEAKQEKSMYGVYNTFTTEERWALH 142
           C+IC + F        HQ +H+        +  +  +     + + + +T          
Sbjct: 388 CNICGKSFSQSSNLATHQTVHSGNKPYKCDECGKTFKRSSSLTTHQIIHT---------- 437

Query: 143 PCSKSDPMYSMKRRKNIHACTICGKMFPSQSKLDRHVLIHTGQRPFKCVLCTKSFRQSTH 202
                         +  + C +C K+F  +S+L RH   HTG++P+KC  C K F Q++H
Sbjct: 438 -------------GEKPYTCDVCDKVFSQRSQLARHQRSHTGEKPYKCNECGKVFSQTSH 484

Query: 203 LKIHQLTHSEERPFQCCFCQKGFKIQSKLLKHKQIHTRNKAFRALLLKKRRTESRPLPNK 262
           L  H+  H+ E+P++C  C K FK  S L +HK IHTR K ++     K  +E+  L   
Sbjct: 485 LVGHRRIHTGEKPYKCDKCGKAFKQGSLLTRHKIIHTREKRYQCGECGKVFSENSCLVRH 544

Query: 263 LNANQGG--FENGEIGES-EENNPLDVHSIYIV---PFQCPKCEKCFESEQILNEHSCFA 316
           L  + G   ++    G+    +  L +H        PFQC +C   F +      +SC  
Sbjct: 545 LRIHTGEQPYKCNVCGKVFNYSGNLSIHKRIHTGEKPFQCNECGTVFRN------YSCL- 597

Query: 317 ARSGKIPSRFKRSYNYKTIVKKILAKLKRARSKKLDN----FQSEK--KVFK--KSFLRN 368
           AR  +I +  ++ Y      K        +  K++      FQ  +  KVF       R+
Sbjct: 598 ARHLRIHTG-QKPYKCNVCGKVFNDSGNLSNHKRIHTGEKPFQCNECGKVFSYYSCLARH 656

Query: 369 CDLISGEQ-------SSEQTQRTFVGSLGKHGTYKTIGNRKKKTLTLPFSWQNMGKNLKG 421
             + +GE+           TQR+   SL KH    T G +       P++    G     
Sbjct: 657 RKIHTGEKPYKCNDCGKAYTQRS---SLTKHLIIHT-GEK-------PYNCNEFGG---A 702

Query: 422 ILTTENILSIDNSVNKKDLSICGSSGEEFFNNCEVLQCGFSVPRENIRTRHKICPCDKCE 481
            + +  +     +   +    C   G  F +   +    +   R      +K   C +C 
Sbjct: 703 FIQSSKLARYHRNPTGEKPHKCSHCGRTFSH---ITGLTYHQRRHTGEMPYK---CIECG 756

Query: 482 KVFPSISKLKRHYLIHTGQRPFGCNICGKSFRQSAHLKRHEQTHNEKSPYA-SLCQVEFG 540
           +VF S S L RH  IHTG++P+ CN CGK FR  + L RH   H  + PY  + C   F 
Sbjct: 757 QVFNSTSNLARHRRIHTGEKPYKCNECGKVFRHQSTLARHRSIHTGEKPYVCNECGKAFR 816

Query: 541 NFNNLSNHSGNNVNYNASQQCQAPGVQKYEVSESDQMSGVKAESQDFIPGSTGQPCLPNV 600
             + L NH           Q    G + Y+ +E                   G+  +   
Sbjct: 817 VRSILVNH-----------QKMHTGDKPYKCNEC------------------GKAFIERS 847

Query: 601 LLESEQSNPFCSYSEHQEKNDVFLYRCSVCAKSFRSPSKLERHYLIHAGQKPFECSVCGK 660
            L   Q N       H  +     Y+C  C K+F   S L +H +IH+G+KP++C+ CGK
Sbjct: 848 KLVYHQRN-------HTGEKP---YKCIECGKAFGRFSCLNKHQMIHSGEKPYKCNECGK 897

Query: 661 TFRQAPHWKRHQLTHFKE 678
           +F       +HQ  H  E
Sbjct: 898 SFISRSGLTKHQTKHTAE 915



 Score =  203 bits (517), Expect = 4e-52
 Identities = 169/680 (24%), Positives = 271/680 (39%), Gaps = 105/680 (15%)

Query: 33  FKHFETPSKLARHYLIHTGQKPFECDVCHKTFRQLVHLERHQLTHSL--PFKCSICQRHF 90
           F     P++L +    H  +KP+ C  C K FR    L  HQ+ H+   P+KC+ C + F
Sbjct: 199 FLQLSLPTQLEK---THIREKPYMCKGCGKAFRVSSSLINHQMVHTTEKPYKCNECGKAF 255

Query: 91  KNLKTFVKHQQLHNETYQNNVKQVRRLLEAKQEKSMYGVYNTFTTEERWALHPCSKS-DP 149
                   HQ +H            ++   +Q   +     + T E+ +  + C KS   
Sbjct: 256 HRGSLLTIHQIVHTRGKPYQCGVCGKIF--RQNSDLVNHRRSHTGEKPYKCNECGKSFSQ 313

Query: 150 MYSMKRRKNIHA------CTICGKMFPSQSKLDRHVLIHTGQRPFKCVLCTKSFRQSTHL 203
            Y++   + IH       C  CGK F   S L  H +IHTG++P++C +C K FRQ+++L
Sbjct: 314 SYNLAIHQRIHTGEKPYKCNECGKTFKQGSCLTTHQIIHTGEKPYQCDICGKVFRQNSNL 373

Query: 204 KIHQLTHSEERPFQCCFCQKGFKIQSKLLKHKQIHTRNKAFRALLLKKRRTESRPLPNKL 263
             HQ  H+ E+P++C  C K F   S L  H+ +H+ NK ++                  
Sbjct: 374 VNHQRIHTGEKPYKCNICGKSFSQSSNLATHQTVHSGNKPYKC----------------- 416

Query: 264 NANQGGFENGEIGES-EENNPLDVHSIYIV---PFQCPKCEKCFESEQILNEHSCFAARS 319
                     E G++ + ++ L  H I      P+ C  C+K F     L  H    + +
Sbjct: 417 ---------DECGKTFKRSSSLTTHQIIHTGEKPYTCDVCDKVFSQRSQLARHQ--RSHT 465

Query: 320 GKIPSRFKRSYNYKTIVKKILAKLKRARSKKLDNFQSEKKVFKKSFLRNCDLISGEQSSE 379
           G+ P +        +    ++   +    +K        K FK+  L             
Sbjct: 466 GEKPYKCNECGKVFSQTSHLVGHRRIHTGEKPYKCDKCGKAFKQGSL------------- 512

Query: 380 QTQRTFVGSLGKHGTYKTIGNRKKKTLTLPFSWQNMGKNLKGILTTENILSIDNSVNKKD 439
                    L +H   K I  R+K+     +     GK           L I        
Sbjct: 513 ---------LTRH---KIIHTREKR-----YQCGECGKVFSENSCLVRHLRIHTGEQPYK 555

Query: 440 LSICGSSGEEFFNNCEVLQCGFSVPRENIRTRHKICPCDKCEKVFPSISKLKRHYLIHTG 499
            ++CG    + FN    L        + I T  K   C++C  VF + S L RH  IHTG
Sbjct: 556 CNVCG----KVFNYSGNLSI-----HKRIHTGEKPFQCNECGTVFRNYSCLARHLRIHTG 606

Query: 500 QRPFGCNICGKSFRQSAHLKRHEQTHNEKSPY-ASLCQVEFGNFNNLSNHSGNNVNYNAS 558
           Q+P+ CN+CGK F  S +L  H++ H  + P+  + C   F  ++ L+ H   +      
Sbjct: 607 QKPYKCNVCGKVFNDSGNLSNHKRIHTGEKPFQCNECGKVFSYYSCLARHRKIHTG-EKP 665

Query: 559 QQCQAPGVQKYEVSESDQMSGVKAESQDFIPGSTGQPCLPNVLLESEQSNPF------CS 612
            +C   G    + S   +   +    + +     G   + +  L     NP       CS
Sbjct: 666 YKCNDCGKAYTQRSSLTKHLIIHTGEKPYNCNEFGGAFIQSSKLARYHRNPTGEKPHKCS 725

Query: 613 Y-----------SEHQEKNDVFL-YRCSVCAKSFRSPSKLERHYLIHAGQKPFECSVCGK 660
           +           + HQ ++   + Y+C  C + F S S L RH  IH G+KP++C+ CGK
Sbjct: 726 HCGRTFSHITGLTYHQRRHTGEMPYKCIECGQVFNSTSNLARHRRIHTGEKPYKCNECGK 785

Query: 661 TFRQAPHWKRHQLTHFKERP 680
            FR      RH+  H  E+P
Sbjct: 786 VFRHQSTLARHRSIHTGEKP 805



 Score =  194 bits (492), Expect = 3e-49
 Identities = 151/553 (27%), Positives = 231/553 (41%), Gaps = 68/553 (12%)

Query: 25  RPYVCNICFKHFETPSKLARHYLIHTGQKPFECDVCHKTFRQLVHLERHQLTHS--LPFK 82
           +PY CNIC K F   S LA H  +H+G KP++CD C KTF++   L  HQ+ H+   P+ 
Sbjct: 384 KPYKCNICGKSFSQSSNLATHQTVHSGNKPYKCDECGKTFKRSSSLTTHQIIHTGEKPYT 443

Query: 83  CSICQRHFKNLKTFVKHQQLHNETYQNNVKQVRRLLEAKQEKSMYGVYNTFTTEERWALH 142
           C +C + F       +HQ+ H         +  ++    Q   + G     T E+ +   
Sbjct: 444 CDVCDKVFSQRSQLARHQRSHTGEKPYKCNECGKVFS--QTSHLVGHRRIHTGEKPYKCD 501

Query: 143 PCSKSDPMYSM-KRRKNIHA------CTICGKMFPSQSKLDRHVLIHTGQRPFKCVLCTK 195
            C K+    S+  R K IH       C  CGK+F   S L RH+ IHTG++P+KC +C K
Sbjct: 502 KCGKAFKQGSLLTRHKIIHTREKRYQCGECGKVFSENSCLVRHLRIHTGEQPYKCNVCGK 561

Query: 196 SFRQSTHLKIHQLTHSEERPFQCCFCQKGFKIQSKLLKHKQIHTRNKAFRALLLKKRRTE 255
            F  S +L IH+  H+ E+PFQC  C   F+  S L +H +IHT  K ++  +  K   +
Sbjct: 562 VFNYSGNLSIHKRIHTGEKPFQCNECGTVFRNYSCLARHLRIHTGQKPYKCNVCGKVFND 621

Query: 256 SRPLPN--KLNANQGGFENGEIGESEENNPLDVHSIYIV------------PFQCPKCEK 301
           S  L N  +++  +  F+  E G+        V S Y              P++C  C K
Sbjct: 622 SGNLSNHKRIHTGEKPFQCNECGK--------VFSYYSCLARHRKIHTGEKPYKCNDCGK 673

Query: 302 CFESEQILNEHSCFAARSGKIPSRFKRSYNYKTIVKKILAKLKRARSKKLDNFQSEKKVF 361
            +     L +H      +G+ P      YN        +   K AR  +  N   EK   
Sbjct: 674 AYTQRSSLTKH--LIIHTGEKP------YNCNEFGGAFIQSSKLARYHR--NPTGEKPHK 723

Query: 362 KKSFLRNCDLISG------EQSSEQTQRTFVGSLGKHGTYKTIGNRKKKTLTLPFSWQNM 415
                R    I+G        + E   +        + T     +R+  T   P+     
Sbjct: 724 CSHCGRTFSHITGLTYHQRRHTGEMPYKCIECGQVFNSTSNLARHRRIHTGEKPYKCNEC 783

Query: 416 GKNLKGILTTENILSIDNSVNKKDLSICGSS---------------GEEFF--NNC--EV 456
           GK  +   T     SI         + CG +               G++ +  N C    
Sbjct: 784 GKVFRHQSTLARHRSIHTGEKPYVCNECGKAFRVRSILVNHQKMHTGDKPYKCNECGKAF 843

Query: 457 LQCGFSVPRENIRTRHKICPCDKCEKVFPSISKLKRHYLIHTGQRPFGCNICGKSFRQSA 516
           ++    V  +   T  K   C +C K F   S L +H +IH+G++P+ CN CGKSF   +
Sbjct: 844 IERSKLVYHQRNHTGEKPYKCIECGKAFGRFSCLNKHQMIHSGEKPYKCNECGKSFISRS 903

Query: 517 HLKRHEQTHNEKS 529
            L +H+  H  +S
Sbjct: 904 GLTKHQTKHTAES 916



 Score =  134 bits (337), Expect = 3e-31
 Identities = 156/640 (24%), Positives = 254/640 (39%), Gaps = 98/640 (15%)

Query: 66  QLVHLERHQLTHSLPFKCSICQRHFKNLKTFVKHQQLHNE----TYQNNVKQVRRLLEAK 121
           Q V LERH+      F     Q++ ++L+   K  +++ +    TY+NN+   R      
Sbjct: 71  QTVTLERHECYDVENFYLREIQKNLQDLEFQWKDGEINYKEVPMTYKNNLNGKRG----- 125

Query: 122 QEKSMYGVYNTFTTEERWALHPCSKSDPMYSMKRRKNIHACTICGKMFPSQSKLDRHVLI 181
            + S   V N    E +  L   S+   +   +    I+ C        S+  ++   L+
Sbjct: 126 -QHSQEDVENK-CIENQLTLSFQSRLTELQKFQTEGKIYECN------QSEKTVNNSSLV 177

Query: 182 HTGQRPFKCVLCTKSFR-QSTHLKIH-----QLTHSEERPFQCCFCQKGFKIQSKLLKHK 235
              QR    V    S + ++  L++      + TH  E+P+ C  C K F++ S L+ H+
Sbjct: 178 SPLQRILPSVQTNISKKYENEFLQLSLPTQLEKTHIREKPYMCKGCGKAFRVSSSLINHQ 237

Query: 236 QIHTRNKAFRALLLKKRRTESRPLPNKLNANQGGFENGEIGESEENNPLDVHSIYIV--- 292
            +HT  K                 P K N     F  G +        L +H I      
Sbjct: 238 MVHTTEK-----------------PYKCNECGKAFHRGSL--------LTIHQIVHTRGK 272

Query: 293 PFQCPKCEKCFESEQILNEHSCFAARSGKIPSR-------FKRSYNYKTIVKKILAKLKR 345
           P+QC  C K F     L  H    + +G+ P +       F +SYN   I ++I    K 
Sbjct: 273 PYQCGVCGKIFRQNSDLVNHR--RSHTGEKPYKCNECGKSFSQSYNL-AIHQRIHTGEKP 329

Query: 346 ARSKKLDNFQSEKKVFKK-SFLRNCDLISGEQSSEQTQRTFVGSLGKHGTYKTIGNRKKK 404
            +  +        K FK+ S L    +I      +  Q    G + +  +   + +++  
Sbjct: 330 YKCNECG------KTFKQGSCLTTHQII--HTGEKPYQCDICGKVFRQNS-NLVNHQRIH 380

Query: 405 TLTLPFSWQNMGKNL--KGILTTENILSIDNSVNKKDLSICGSSGEEFFNNCEVLQCGFS 462
           T   P+     GK+      L T   +   N   K     C   G+ F  +  +      
Sbjct: 381 TGEKPYKCNICGKSFSQSSNLATHQTVHSGNKPYK-----CDECGKTFKRSSSL------ 429

Query: 463 VPRENIRTRHKICPCDKCEKVFPSISKLKRHYLIHTGQRPFGCNICGKSFRQSAHLKRHE 522
              + I T  K   CD C+KVF   S+L RH   HTG++P+ CN CGK F Q++HL  H 
Sbjct: 430 TTHQIIHTGEKPYTCDVCDKVFSQRSQLARHQRSHTGEKPYKCNECGKVFSQTSHLVGHR 489

Query: 523 QTHNEKSPY-ASLCQVEFGNFNNLSNHSGNNVNYNASQQCQAPGVQKYEVSESDQMSGVK 581
           + H  + PY    C   F   + L+ H    + +   ++ Q     K     S  +  ++
Sbjct: 490 RIHTGEKPYKCDKCGKAFKQGSLLTRH---KIIHTREKRYQCGECGKVFSENSCLVRHLR 546

Query: 582 AESQDFIPGSTGQPCLPNVLLESEQSNPFCSYSEHQE-KNDVFLYRCSVCAKSFRSPSKL 640
             + +       QP   NV    +  N   + S H+        ++C+ C   FR+ S L
Sbjct: 547 IHTGE-------QPYKCNVC--GKVFNYSGNLSIHKRIHTGEKPFQCNECGTVFRNYSCL 597

Query: 641 ERHYLIHAGQKPFECSVCGKTFRQAPHWKRHQLTHFKERP 680
            RH  IH GQKP++C+VCGK F  + +   H+  H  E+P
Sbjct: 598 ARHLRIHTGQKPYKCNVCGKVFNDSGNLSNHKRIHTGEKP 637



 Score = 70.9 bits (172), Expect = 4e-12
 Identities = 34/82 (41%), Positives = 46/82 (56%), Gaps = 2/82 (2%)

Query: 24  NRPYVCNICFKHFETPSKLARHYLIHTGQKPFECDVCHKTFRQLVHLERHQLTHS--LPF 81
           ++PY CN C K F   SKL  H   HTG+KP++C  C K F +   L +HQ+ HS   P+
Sbjct: 831 DKPYKCNECGKAFIERSKLVYHQRNHTGEKPYKCIECGKAFGRFSCLNKHQMIHSGEKPY 890

Query: 82  KCSICQRHFKNLKTFVKHQQLH 103
           KC+ C + F +     KHQ  H
Sbjct: 891 KCNECGKSFISRSGLTKHQTKH 912


>gi|54291708 zinc finger protein 780B [Homo sapiens]
          Length = 833

 Score =  220 bits (560), Expect = 4e-57
 Identities = 186/675 (27%), Positives = 281/675 (41%), Gaps = 102/675 (15%)

Query: 24  NRPYVCNICFKHFETPSKLARHYLIHTGQKPFECDVCHKTFRQLVHLERHQLTHS--LPF 81
           ++PY C  C K+F   S L +H  IHTG+KP++C  C K F+  + L RHQ  H+    F
Sbjct: 162 HKPYECKECGKYFSCGSNLIQHQSIHTGEKPYKCKECGKAFQLHIQLTRHQKFHTGEKTF 221

Query: 82  KCSICQRHFKNLKTFVKHQQLHNETYQNNVKQVRRLLEAKQEKSMYGVYNTFTTEERWAL 141
           +C  C + F       +H+ +H          V++L E K+                   
Sbjct: 222 ECKECGKAFNLPTQLNRHKNIHT---------VKKLFECKE------------------- 253

Query: 142 HPCSKS-DPMYSMKRRKNIHA------CTICGKMFPSQSKLDRHVLIHTGQRPFKCVLCT 194
             C KS +   ++ + ++IHA      C  CGK F   S L +H  IH+ ++PF C  C 
Sbjct: 254 --CGKSFNRSSNLTQHQSIHAGVKPYQCKECGKAFNRGSNLIQHQKIHSNEKPFVCRECE 311

Query: 195 KSFRQSTHLKIHQLTHSEERPFQCCFCQKGFKIQSKLLKHKQIHTRNKAFRALLLKKRRT 254
            +FR    L  H   H+ E+PF+C  C+K F + +KL++H++IH   K F      K  +
Sbjct: 312 MAFRYHYQLIEHCRIHTGEKPFECKECRKAFTLLTKLVRHQKIHMGEKPFECRECGKAFS 371

Query: 255 ESRPLPNKLNANQG--GFENGEIGES--EENNPLDVHSIY--IVPFQCPKCEKCFESEQI 308
               L    N + G   FE  E G+S    +N +   SI+  + P++C +C K F     
Sbjct: 372 LLNQLNRHKNIHTGEKPFECKECGKSFNRSSNLIQHQSIHADVKPYECKECGKGFNRGAN 431

Query: 309 LNEHSCFAARSGKIPSRFKRSYNYKTIVKKILAKLKRARSKKLDNFQSEKKVFKKSFLRN 368
           L +H        KI S      N K  V +      R               +    +++
Sbjct: 432 LIQHQ-------KIHS------NEKPFVCRECEMAFR---------------YHYQLIQH 463

Query: 369 CDLISGEQSSE--QTQRTFVGSLGKHGTYKTIGNRKKKTLTLPFSWQNMGKNLKGILTTE 426
           C + +G +  E  +  + F   L +   +K I   +K     PF  ++ GK         
Sbjct: 464 CQIHTGGKPFECKECGKAF-SLLTQLARHKNIHTGEK-----PFECKDCGKAFN---RGS 514

Query: 427 NILSIDNSVNKKDLSICGSSGEEFFNNCEVLQCGFSVPRENIRTRHKICPCDKCEKVFPS 486
           N++   +    +    C   G+ F  + ++ Q       E   T  K   C +C K F  
Sbjct: 515 NLVQHQSIHTGEKPYECKECGKAFRLHLQLSQ------HEKTHTGEKPFECKECGKFFRR 568

Query: 487 ISKLKRHYLIHTGQRPFGCNICGKSFRQSAHLKRHEQTHNEKSPY-ASLCQVEFGNFNNL 545
            S L +H  IHTG++PF C  CGK+FR   HL RH++ H  + P+    C   F     L
Sbjct: 569 GSNLNQHRSIHTGKKPFECKECGKAFRLHMHLIRHQKFHTGEKPFECKECGKAFSLHTQL 628

Query: 546 SNHSGNNVNYNASQQCQAPGVQKYEVSESDQMSGVKAESQDFIPGSTGQPCLPNVLLESE 605
            NH  N        +C+  G     VS   Q   + A  + +     G+         S 
Sbjct: 629 -NHHKNIHTGEKPFKCKECGKSFNRVSNLVQHQSIHAGVKPYECKECGKGF-------SR 680

Query: 606 QSNPFCSYSEHQEKNDVFLYRCSVCAKSFRSPSKLERHYLIHAGQKPFECSVCGKTFRQA 665
            SN       H        + C  C K+FR   +L  HY IH G+KPFEC  CGK F   
Sbjct: 681 VSNLIQHQKTHSSAKP---FVCKECRKTFRYHYQLTEHYRIHTGEKPFECKECGKAFGLL 737

Query: 666 PHWKRHQLTHFKERP 680
               +HQ+ H  E+P
Sbjct: 738 TQLAQHQIIHTGEKP 752



 Score =  200 bits (508), Expect = 4e-51
 Identities = 171/667 (25%), Positives = 278/667 (41%), Gaps = 104/667 (15%)

Query: 25  RPYVCNICFKHFETPSKLARHYLIHTGQKPFECDVCHKTFRQLVHLERHQLTHS--LPFK 82
           + + C  C K F  P++L RH  IHT +K FEC  C K+F +  +L +HQ  H+   P++
Sbjct: 219 KTFECKECGKAFNLPTQLNRHKNIHTVKKLFECKECGKSFNRSSNLTQHQSIHAGVKPYQ 278

Query: 83  CSICQRHFKNLKTFVKHQQLHNETYQNNVKQVRRLLEAKQEKSMYGVYNTFTTEERWALH 142
           C  C + F      ++HQ++H+       ++    +  +    +       T E+ +   
Sbjct: 279 CKECGKAFNRGSNLIQHQKIHSNEKPFVCRECE--MAFRYHYQLIEHCRIHTGEKPFECK 336

Query: 143 PCSKSDPMYS-MKRRKNIHA------CTICGKMFPSQSKLDRHVLIHTGQRPFKCVLCTK 195
            C K+  + + + R + IH       C  CGK F   ++L+RH  IHTG++PF+C  C K
Sbjct: 337 ECRKAFTLLTKLVRHQKIHMGEKPFECRECGKAFSLLNQLNRHKNIHTGEKPFECKECGK 396

Query: 196 SFRQSTHLKIHQLTHSEERPFQCCFCQKGFKIQSKLLKHKQIHTRNKAFRALLLKKRRTE 255
           SF +S++L  HQ  H++ +P++C  C KGF   + L++H++IH+  K F     +     
Sbjct: 397 SFNRSSNLIQHQSIHADVKPYECKECGKGFNRGANLIQHQKIHSNEKPFVCRECEMAFRY 456

Query: 256 SRPLPNKLNANQGG--FENGEIGE-----SEENNPLDVHSIYIVPFQCPKCEKCFESEQI 308
              L      + GG  FE  E G+     ++     ++H+    PF+C  C K F     
Sbjct: 457 HYQLIQHCQIHTGGKPFECKECGKAFSLLTQLARHKNIHT-GEKPFECKDCGKAFNRGSN 515

Query: 309 LNEHSCFAARSGKIPSRFKRSYNYKTIVKKILAKLKRARSKKLDNFQS--EKKVFKKSFL 366
           L +H   +  +G+ P      Y  K   K     L+ ++ +K    +   E K   K F 
Sbjct: 516 LVQHQ--SIHTGEKP------YECKECGKAFRLHLQLSQHEKTHTGEKPFECKECGKFFR 567

Query: 367 RNCDLISGEQSSEQTQRTFVGSLGKHGTYKTIGNRKKKTLTLPFSWQNMGKNLKGILTTE 426
           R  +L                       +++I   KK     PF  +  GK  +  L   
Sbjct: 568 RGSNL---------------------NQHRSIHTGKK-----PFECKECGKAFR--LHMH 599

Query: 427 NILSIDNSVNKKDLSICGSSGEEFFNNCEVLQCGFSVPRENIRTRHKICPCDKCEKVFPS 486
            I        +K    C   G+ F  + ++         +NI T  K   C +C K F  
Sbjct: 600 LIRHQKFHTGEKPFE-CKECGKAFSLHTQLNH------HKNIHTGEKPFKCKECGKSFNR 652

Query: 487 ISKLKRHYLIHTGQRPFGCNICGKSFRQSAHLKRHEQTHNEKSPY-ASLCQVEFGNFNNL 545
           +S L +H  IH G +P+ C  CGK F + ++L +H++TH+   P+    C+  F     L
Sbjct: 653 VSNLVQHQSIHAGVKPYECKECGKGFSRVSNLIQHQKTHSSAKPFVCKECRKTFRYHYQL 712

Query: 546 SNHSGNNVNYNASQQCQAPGVQKYEVSESDQMSGVKAESQDFIPGSTGQPCLPNVLLESE 605
           + H   +            G + +E  E  +  G+  +        TG+           
Sbjct: 713 TEHYRIHT-----------GEKPFECKECGKAFGLLTQLAQHQIIHTGE----------- 750

Query: 606 QSNPFCSYSEHQEKNDVFLYRCSVCAKSFRSPSKLERHYLIHAGQKPFECSVCGKTFRQA 665
              PF               +C  C K+F   S L +   IH G+KP+EC  CGK FR  
Sbjct: 751 --KPF---------------KCKECGKAFNRGSNLVQPQSIHTGEKPYECKECGKAFRLH 793

Query: 666 PHWKRHQ 672
                HQ
Sbjct: 794 LQLSLHQ 800



 Score =  169 bits (427), Expect = 1e-41
 Identities = 141/530 (26%), Positives = 222/530 (41%), Gaps = 76/530 (14%)

Query: 25  RPYVCNICFKHFETPSKLARHYLIHTGQKPFECDVCHKTFRQLVHLERHQLTHS--LPFK 82
           +P+ C  C K F   +KL RH  IH G+KPFEC  C K F  L  L RH+  H+   PF+
Sbjct: 331 KPFECKECRKAFTLLTKLVRHQKIHMGEKPFECRECGKAFSLLNQLNRHKNIHTGEKPFE 390

Query: 83  CSICQRHFKNLKTFVKHQQLHNETYQNNVKQVRRLLEAKQEKSMYGVYNTFTTEERWALH 142
           C  C + F      ++HQ +H +      K+  +     +  ++       + E+ +   
Sbjct: 391 CKECGKSFNRSSNLIQHQSIHADVKPYECKECGKGFN--RGANLIQHQKIHSNEKPFVCR 448

Query: 143 PCSKSDPM-YSMKRRKNIHA------CTICGKMFPSQSKLDRHVLIHTGQRPFKCVLCTK 195
            C  +    Y + +   IH       C  CGK F   ++L RH  IHTG++PF+C  C K
Sbjct: 449 ECEMAFRYHYQLIQHCQIHTGGKPFECKECGKAFSLLTQLARHKNIHTGEKPFECKDCGK 508

Query: 196 SFRQSTHLKIHQLTHSEERPFQCCFCQKGFKIQSKLLKHKQIHTRNKAFRALLLKK--RR 253
           +F + ++L  HQ  H+ E+P++C  C K F++  +L +H++ HT  K F      K  RR
Sbjct: 509 AFNRGSNLVQHQSIHTGEKPYECKECGKAFRLHLQLSQHEKTHTGEKPFECKECGKFFRR 568

Query: 254 TESRPLPNKLNANQGGFENGEIGESEENNPLDVHSIYIV-------PFQCPKCEKCFESE 306
             +      ++  +  FE  E G++     L +H I          PF+C +C K F   
Sbjct: 569 GSNLNQHRSIHTGKKPFECKECGKAFR---LHMHLIRHQKFHTGEKPFECKECGKAFSLH 625

Query: 307 QILNEHSCFAARSGKIPSRFK---RSYNYKTIVKKILAKLKRARSKKLDNFQSEKKVFKK 363
             LN H      +G+ P + K   +S+N        ++ L + +S        E K   K
Sbjct: 626 TQLNHHKNI--HTGEKPFKCKECGKSFNR-------VSNLVQHQSIHAGVKPYECKECGK 676

Query: 364 SFLRNCDLISGEQSSEQTQRTFVGSLGKHGT---YKTIGNRKKKTLTLPFSWQNMGKNLK 420
            F R  +LI   Q +  + + FV    +      Y+   + +  T   PF  +  GK   
Sbjct: 677 GFSRVSNLIQ-HQKTHSSAKPFVCKECRKTFRYHYQLTEHYRIHTGEKPFECKECGKAF- 734

Query: 421 GILTTENILSIDNSVNKKDLSICGSSGEEFFNNCEVLQCGFSVPRENIRTRHKICPCDKC 480
           G+LT                                         + I T  K   C +C
Sbjct: 735 GLLTQ------------------------------------LAQHQIIHTGEKPFKCKEC 758

Query: 481 EKVFPSISKLKRHYLIHTGQRPFGCNICGKSFRQSAHLKRHEQTHNEKSP 530
            K F   S L +   IHTG++P+ C  CGK+FR    L  H++    ++P
Sbjct: 759 GKAFNRGSNLVQPQSIHTGEKPYECKECGKAFRLHLQLSLHQKLVQVRNP 808



 Score =  150 bits (379), Expect = 4e-36
 Identities = 139/563 (24%), Positives = 233/563 (41%), Gaps = 87/563 (15%)

Query: 181 IHTGQRPFKCVLCTKSFRQSTHLKIHQLTHSEERPFQCCFCQKGFKIQSKLLKHKQIHTR 240
           IH   +P++C  C K F   ++L  HQ  H+ E+P++C  C K F++  +L +H++ HT 
Sbjct: 158 IHNTHKPYECKECGKYFSCGSNLIQHQSIHTGEKPYKCKECGKAFQLHIQLTRHQKFHTG 217

Query: 241 NKAFRALLLKKRRTESRPLPNKLNANQG------GFENGEIGES--EENNPLDVHSIY-- 290
            K F      K   ++  LP +LN ++        FE  E G+S    +N     SI+  
Sbjct: 218 EKTFEC----KECGKAFNLPTQLNRHKNIHTVKKLFECKECGKSFNRSSNLTQHQSIHAG 273

Query: 291 IVPFQCPKCEKCFESEQILNEH-------------SCFAA-------------RSGKIPS 324
           + P+QC +C K F     L +H              C  A              +G+ P 
Sbjct: 274 VKPYQCKECGKAFNRGSNLIQHQKIHSNEKPFVCRECEMAFRYHYQLIEHCRIHTGEKPF 333

Query: 325 RFKRSYNYKTIVKKILAKLKRARSKKLDNFQSEKKVFK--KSFLRNCDLISGEQSSE--Q 380
             K      T++ K++   K    +K    +   K F       R+ ++ +GE+  E  +
Sbjct: 334 ECKECRKAFTLLTKLVRHQKIHMGEKPFECRECGKAFSLLNQLNRHKNIHTGEKPFECKE 393

Query: 381 TQRTFVGSLGKHGTYKTIGNRKKKTLTLPFSWQNMGKNLK---GILTTENILSIDNSVNK 437
             ++F      + +   I ++       P+  +  GK       ++  + I S +     
Sbjct: 394 CGKSF------NRSSNLIQHQSIHADVKPYECKECGKGFNRGANLIQHQKIHSNEKPFVC 447

Query: 438 KDLSICGSSGEEFFNNCEV---------LQCG--FSV-----PRENIRTRHKICPCDKCE 481
           ++  +      +   +C++          +CG  FS+       +NI T  K   C  C 
Sbjct: 448 RECEMAFRYHYQLIQHCQIHTGGKPFECKECGKAFSLLTQLARHKNIHTGEKPFECKDCG 507

Query: 482 KVFPSISKLKRHYLIHTGQRPFGCNICGKSFRQSAHLKRHEQTHNEKSPYASLCQVEFGN 541
           K F   S L +H  IHTG++P+ C  CGK+FR    L +HE+TH  + P+   C+ E G 
Sbjct: 508 KAFNRGSNLVQHQSIHTGEKPYECKECGKAFRLHLQLSQHEKTHTGEKPFE--CK-ECGK 564

Query: 542 FNNLSNHSGNNVNYNASQQCQAPGVQKYEVSESDQMSGVKAESQDFIPGSTGQPCLPNVL 601
           F       G+N+N + S        +  E  ++ ++       Q F  G     C     
Sbjct: 565 F----FRRGSNLNQHRSIHTGKKPFECKECGKAFRLHMHLIRHQKFHTGEKPFEC----- 615

Query: 602 LESEQSNPFCSYSEHQEKNDVFL----YRCSVCAKSFRSPSKLERHYLIHAGQKPFECSV 657
              E    F  +++     ++      ++C  C KSF   S L +H  IHAG KP+EC  
Sbjct: 616 --KECGKAFSLHTQLNHHKNIHTGEKPFKCKECGKSFNRVSNLVQHQSIHAGVKPYECKE 673

Query: 658 CGKTFRQAPHWKRHQLTHFKERP 680
           CGK F +  +  +HQ TH   +P
Sbjct: 674 CGKGFSRVSNLIQHQKTHSSAKP 696



 Score =  107 bits (266), Expect = 5e-23
 Identities = 63/217 (29%), Positives = 104/217 (47%), Gaps = 11/217 (5%)

Query: 25  RPYVCNICFKHFETPSKLARHYLIHTGQKPFECDVCHKTFRQLVHLERHQLTHS--LPFK 82
           +P+ C  C K F   ++L  H  IHTG+KPF+C  C K+F ++ +L +HQ  H+   P++
Sbjct: 611 KPFECKECGKAFSLHTQLNHHKNIHTGEKPFKCKECGKSFNRVSNLVQHQSIHAGVKPYE 670

Query: 83  CSICQRHFKNLKTFVKHQQLHNETYQNNVKQVRRLLEAKQEKSMYGVYNTFTTEERWALH 142
           C  C + F  +   ++HQ+ H+       K+ R+      + + +  Y   T E+ +   
Sbjct: 671 CKECGKGFSRVSNLIQHQKTHSSAKPFVCKECRKTFRYHYQLTEH--YRIHTGEKPFECK 728

Query: 143 PCSKSDPMYS-MKRRKNIHA------CTICGKMFPSQSKLDRHVLIHTGQRPFKCVLCTK 195
            C K+  + + + + + IH       C  CGK F   S L +   IHTG++P++C  C K
Sbjct: 729 ECGKAFGLLTQLAQHQIIHTGEKPFKCKECGKAFNRGSNLVQPQSIHTGEKPYECKECGK 788

Query: 196 SFRQSTHLKIHQLTHSEERPFQCCFCQKGFKIQSKLL 232
           +FR    L +HQ       P       +   I S LL
Sbjct: 789 AFRLHLQLSLHQKLVQVRNPLNVRNVGQPSDISSNLL 825


>gi|119120877 zinc finger protein 721 [Homo sapiens]
          Length = 923

 Score =  219 bits (559), Expect = 5e-57
 Identities = 182/698 (26%), Positives = 299/698 (42%), Gaps = 126/698 (18%)

Query: 27  YVCNICFKHFETPSKLARHYLIHTGQKPFECDVCHKTFRQLVHLERHQLTHS--LPFKCS 84
           + CN C K F+  S L +H  IH G+KP+ C+   K F     L +H+  H+   P+KC 
Sbjct: 109 FKCNECGKSFQKFSDLTQHKGIHAGEKPYTCEERGKDFGWYTDLNQHKKIHTGEKPYKCE 168

Query: 85  ICQRHFKNLKTFVKHQQLHNETYQNNVKQVRRLLEAKQEKSMYGVYNTFTTEERWALHPC 144
            C + F        H+++HN                 +EK+       +T E+R      
Sbjct: 169 ECGKAFNRSTNLTAHKRIHN-----------------REKA-------YTGEDRDRAFGW 204

Query: 145 SKSDPMYSMKRRKNIHA------CTICGKMFPSQSKLDRHVLIHTGQRPFKCVLCTKSFR 198
           S      ++   K IH       C  CGK F   S L++H  IHTG++P+KC  C K   
Sbjct: 205 ST-----NLNEYKKIHTGDKPYKCKECGKAFMHSSHLNKHEKIHTGEKPYKCKECGKVIS 259

Query: 199 QSTHLKIHQLTHSEERPFQCCFCQKGFKIQSKLLKHKQIHTRNKAFRALLLKK--RRTES 256
            S+    H+  H+ E+PF+C  C K F I + L KH++IHT  K +   +  K  R++ +
Sbjct: 260 SSSSFAKHKRIHTGEKPFKCLECGKAFNISTTLTKHRRIHTGEKPYTCEVCGKAFRQSAN 319

Query: 257 RPLPNKLNANQGGFENGEIGES-EENNPLDVHSIYIV---PFQCPKCEKCFESEQILNEH 312
             +  +++  +  +  GE G++  ++  L VH        P++C  C K F     LN+H
Sbjct: 320 LYVHRRIHTGEKPYTCGECGKTFRQSANLYVHRRIHTGEKPYKCEDCGKAFGRYTALNQH 379

Query: 313 SCFAARSGKIPSRFK---RSYNYKTIV---KKILAKLK------RARSKKLD-NFQSEKK 359
                 +G+ P + +   +++N  T +   K+I  + K      R R+  L  N    KK
Sbjct: 380 K--KIHTGEKPYKCEECGKAFNSSTNLTAHKRIHTREKPYTCEDRGRAFGLSTNLNEYKK 437

Query: 360 VFKKSFLRNCDLISGEQSSEQTQRTFVGS--LGKHGTYKTIGNRKKKTLTLPFSWQNMGK 417
           +        C         ++  + F+ S  L KH         K  T   P+  +  GK
Sbjct: 438 IHTGDKPYKC---------KECGKAFIHSLHLNKH--------EKIHTGKKPYKCKQCGK 480

Query: 418 NLKGILTTENILSIDNSVNKKDLSICGSSGEEFFNNCEVLQCGFSVPRENIRTRH----- 472
               ++T+ +  +    ++         +GE+ F   E L+CG +       T+H     
Sbjct: 481 ----VITSSSSFAKHKRIH---------TGEKPF---ECLECGKAFTSSTTLTKHRRIHT 524

Query: 473 --KICPCDKCEKVFPSISKLKRHYLIHTGQRPFGCNICGKSFRQSAHLKRHEQTHNEKSP 530
             K   C+ C K F   + L  H  IHTG++P+ C  CGK+FRQSA+L  H + H  + P
Sbjct: 525 GEKPYTCEVCGKAFRQSAILYVHRRIHTGEKPYTCEECGKTFRQSANLYVHRRIHTGEKP 584

Query: 531 Y-ASLCQVEFGNFNNLSNHSGNNVNYNASQQCQAPGVQKYEVSESDQMSGVKAESQDFIP 589
           Y    C   FG + +L+ H   +       +C+  G      ++ +Q   +    + +  
Sbjct: 585 YKCEECGKAFGRYTDLNQHKKIHTG-EKLYKCEECGKDFVWYTDLNQQKKIYTGEKPYKC 643

Query: 590 GSTGQPCLPNV-------LLESEQSNPFCSYSEHQEKNDVFLYRCSVCAKSFRSPSKLER 642
              G+   P+        +L  EQS                 Y+C  C K+F     L +
Sbjct: 644 EECGKAFAPSTDLNQHTKILTGEQS-----------------YKCEECGKAFGWSIALNQ 686

Query: 643 HYLIHAGQKPFECSVCGKTFRQAPHWKRHQLTHFKERP 680
           H  IH G+KP++C  CGK F ++ +   H+  H +E+P
Sbjct: 687 HKKIHTGEKPYKCEECGKAFSRSRNLTTHRRVHTREKP 724



 Score =  213 bits (541), Expect = 6e-55
 Identities = 177/680 (26%), Positives = 282/680 (41%), Gaps = 96/680 (14%)

Query: 25  RPYVCNICFKHFETPSKLARHYLIHTGQKPFECDVCHKTFRQLVHLERHQLTHS--LPFK 82
           +PY C +C K F   + L  H  IHTG+KP+ C  C KTFRQ  +L  H+  H+   P+K
Sbjct: 303 KPYTCEVCGKAFRQSANLYVHRRIHTGEKPYTCGECGKTFRQSANLYVHRRIHTGEKPYK 362

Query: 83  CSICQRHFKNLKTFVKHQQLHNETYQNNVKQVRRLLEAKQEKSMYGVYNT----FTTEER 138
           C  C + F       +H+++H        ++  +   +    + +   +T    +T E+R
Sbjct: 363 CEDCGKAFGRYTALNQHKKIHTGEKPYKCEECGKAFNSSTNLTAHKRIHTREKPYTCEDR 422

Query: 139 WALHPCSKSDPMYSMKRRKNIHA------CTICGKMFPSQSKLDRHVLIHTGQRPFKCVL 192
                 S +     +   K IH       C  CGK F     L++H  IHTG++P+KC  
Sbjct: 423 GRAFGLSTN-----LNEYKKIHTGDKPYKCKECGKAFIHSLHLNKHEKIHTGKKPYKCKQ 477

Query: 193 CTKSFRQSTHLKIHQLTHSEERPFQCCFCQKGFKIQSKLLKHKQIHTRNKAFRALLLKKR 252
           C K    S+    H+  H+ E+PF+C  C K F   + L KH++IHT  K +   +  K 
Sbjct: 478 CGKVITSSSSFAKHKRIHTGEKPFECLECGKAFTSSTTLTKHRRIHTGEKPYTCEVCGKA 537

Query: 253 RTESRPL--PNKLNANQGGFENGEIGES-EENNPLDVHSIYIV---PFQCPKCEKCFESE 306
             +S  L    +++  +  +   E G++  ++  L VH        P++C +C K F   
Sbjct: 538 FRQSAILYVHRRIHTGEKPYTCEECGKTFRQSANLYVHRRIHTGEKPYKCEECGKAFGRY 597

Query: 307 QILNEHSCFAARSGKIPSRFKRSYNYKTIVKKILAKLKRARSKKLDNFQSEKKVFK--KS 364
             LN+H        KI +  ++ Y  +   K  +      + KK+   +   K  +  K+
Sbjct: 598 TDLNQHK-------KIHTG-EKLYKCEECGKDFVWYTDLNQQKKIYTGEKPYKCEECGKA 649

Query: 365 FLRNCDL------ISGEQSSEQTQRTFVGSLGKHGTYKTIGNRKKKTLT--LPFSWQNMG 416
           F  + DL      ++GEQS +  +       GK   +    N+ KK  T   P+  +  G
Sbjct: 650 FAPSTDLNQHTKILTGEQSYKCEE------CGKAFGWSIALNQHKKIHTGEKPYKCEECG 703

Query: 417 KNLKGILTTENILSIDNSVNKKDLSICGSSGEEFFNNCEVLQCGFSVPRENIRTRHKICP 476
           K       + N+ +      ++    C   G  F  +  + +       + I T  K+  
Sbjct: 704 KAFS---RSRNLTTHRRVHTREKPYKCEDRGRSFGWSTNLNEY------KKIHTGDKLYK 754

Query: 477 CDKCEKVFPSISKLKRHYLIHTGQRPFGCNICGKSFRQSAHLKRHEQTHNEKSPYASL-C 535
           C +C KVF   S L RH  IHTG++P+ C  CGK    S+   +H++ H  + P+  L C
Sbjct: 755 CKECGKVFKQSSHLNRHEKIHTGKKPYKCKECGKVITSSSSFAKHKRIHTGEKPFKCLEC 814

Query: 536 QVEFGNFNNLSNHSGNNVNYNASQQCQAPGVQKYEVSESDQMSGVKAESQDFIPGSTGQP 595
              F +   L+ H   +            G + Y   E       KA  Q  I       
Sbjct: 815 GKAFTSSTTLTKHRRIHT-----------GEKPYTCEECG-----KAFRQSAI------- 851

Query: 596 CLPNVLLESEQSNPFCSYSEHQEKNDVFLYRCSVCAKSFRSPSKLERHYLIHAGQKPFEC 655
                            Y   +       Y C  C K+FR  + L  H  IH G+KP+ C
Sbjct: 852 ----------------LYVHRRIHTGEKPYTCGECGKTFRQSANLYAHKKIHTGEKPYTC 895

Query: 656 SVCGKTFRQAPHWKRHQLTH 675
             CGKTFRQ+ +   H+  H
Sbjct: 896 GDCGKTFRQSANLYAHKKIH 915



 Score =  198 bits (503), Expect = 2e-50
 Identities = 178/711 (25%), Positives = 292/711 (41%), Gaps = 90/711 (12%)

Query: 24  NRPYVCNICFKHFETPSKLARHYLIHTGQKPFECDVCHKTFRQLVHLERHQLTHS--LPF 81
           ++PY C  C K F   S L +H  IHTG+KP++C  C K         +H+  H+   PF
Sbjct: 218 DKPYKCKECGKAFMHSSHLNKHEKIHTGEKPYKCKECGKVISSSSSFAKHKRIHTGEKPF 277

Query: 82  KCSICQRHFKNLKTFVKHQQLHNETYQNNVKQVRRLLEAKQEKSMYGVYNTFTTEERWAL 141
           KC  C + F    T  KH+++H        +   +    +Q  ++Y      T E+ +  
Sbjct: 278 KCLECGKAFNISTTLTKHRRIHTGEKPYTCEVCGKAF--RQSANLYVHRRIHTGEKPYTC 335

Query: 142 HPCSK----SDPMYSMKR---RKNIHACTICGKMFPSQSKLDRHVLIHTGQRPFKCVLCT 194
             C K    S  +Y  +R    +  + C  CGK F   + L++H  IHTG++P+KC  C 
Sbjct: 336 GECGKTFRQSANLYVHRRIHTGEKPYKCEDCGKAFGRYTALNQHKKIHTGEKPYKCEECG 395

Query: 195 KSFRQSTHLKIHQLTHSEERPFQCCFCQKGFKIQSKLLKHKQIHTRNKAFRALLLKKRRT 254
           K+F  ST+L  H+  H+ E+P+ C    + F + + L ++K+IHT +K ++     K   
Sbjct: 396 KAFNSSTNLTAHKRIHTREKPYTCEDRGRAFGLSTNLNEYKKIHTGDKPYKCKECGKAFI 455

Query: 255 ESRPLPN--KLNANQGGFENGEIGESEENNPLDVHSIYI----VPFQCPKCEKCFESEQI 308
            S  L    K++  +  ++  + G+   ++        I     PF+C +C K F S   
Sbjct: 456 HSLHLNKHEKIHTGKKPYKCKQCGKVITSSSSFAKHKRIHTGEKPFECLECGKAFTSSTT 515

Query: 309 LNEHSCFAARSGKIPSRFKRSYNYKTIVKKILAKLKRARSKKLDNFQSEKKVFKKSFLRN 368
           L +H      +G+ P  +      K   +  +  + R        +  E+    K+F ++
Sbjct: 516 LTKHR--RIHTGEKP--YTCEVCGKAFRQSAILYVHRRIHTGEKPYTCEE--CGKTFRQS 569

Query: 369 CDLISGEQSSEQTQRTFVGSLGK-HGTYKTIGNRKK----------KTLTLPFSWQNMGK 417
            +L    +     +       GK  G Y  +   KK          +     F W     
Sbjct: 570 ANLYVHRRIHTGEKPYKCEECGKAFGRYTDLNQHKKIHTGEKLYKCEECGKDFVWYTDLN 629

Query: 418 NLKGILTTENILSIDNSVNKKDLSICGSSGEEFFNNCEVLQCGFSVPRENIRTRHKICPC 477
             K I T E                C   G+ F  + ++ Q         I T  +   C
Sbjct: 630 QQKKIYTGEKPYK------------CEECGKAFAPSTDLNQ------HTKILTGEQSYKC 671

Query: 478 DKCEKVFPSISKLKRHYLIHTGQRPFGCNICGKSFRQSAHLKRHEQTHNEKSPYASLCQV 537
           ++C K F     L +H  IHTG++P+ C  CGK+F +S +L  H + H  + PY   C+ 
Sbjct: 672 EECGKAFGWSIALNQHKKIHTGEKPYKCEECGKAFSRSRNLTTHRRVHTREKPYK--CED 729

Query: 538 E---FGNFNNLSN----HSGNNV--------------NYNASQQCQAPGVQKYEVSESDQ 576
               FG   NL+     H+G+ +              + N  ++    G + Y+  E  +
Sbjct: 730 RGRSFGWSTNLNEYKKIHTGDKLYKCKECGKVFKQSSHLNRHEKIHT-GKKPYKCKECGK 788

Query: 577 M---SGVKAESQDFIPGSTGQPCLPNVLLESEQSNPFCSYSEHQEKNDVFL----YRCSV 629
           +   S   A+ +    G     CL       E    F S +   +   +      Y C  
Sbjct: 789 VITSSSSFAKHKRIHTGEKPFKCL-------ECGKAFTSSTTLTKHRRIHTGEKPYTCEE 841

Query: 630 CAKSFRSPSKLERHYLIHAGQKPFECSVCGKTFRQAPHWKRHQLTHFKERP 680
           C K+FR  + L  H  IH G+KP+ C  CGKTFRQ+ +   H+  H  E+P
Sbjct: 842 CGKAFRQSAILYVHRRIHTGEKPYTCGECGKTFRQSANLYAHKKIHTGEKP 892



 Score =  194 bits (494), Expect = 2e-49
 Identities = 170/703 (24%), Positives = 277/703 (39%), Gaps = 100/703 (14%)

Query: 23  RNRPYVCNICFKHFETPSKLARHYLIHTGQKPFECDVCHKTFRQLVHLERHQLTHS--LP 80
           R + Y      + F   + L  +  IHTG KP++C  C K F    HL +H+  H+   P
Sbjct: 189 REKAYTGEDRDRAFGWSTNLNEYKKIHTGDKPYKCKECGKAFMHSSHLNKHEKIHTGEKP 248

Query: 81  FKCSICQRHFKNLKTFVKHQQLHNETYQNNVKQVRRLLEAKQEKSMYGVYNTFTTEERWA 140
           +KC  C +   +  +F KH+++H        ++  + LE  +    + +  T T   R  
Sbjct: 249 YKCKECGKVISSSSSFAKHKRIHTG------EKPFKCLECGK---AFNISTTLTKHRR-- 297

Query: 141 LHPCSKSDPMYSMKRRKNIHACTICGKMFPSQSKLDRHVLIHTGQRPFKCVLCTKSFRQS 200
           +H   K             + C +CGK F   + L  H  IHTG++P+ C  C K+FRQS
Sbjct: 298 IHTGEKP------------YTCEVCGKAFRQSANLYVHRRIHTGEKPYTCGECGKTFRQS 345

Query: 201 THLKIHQLTHSEERPFQCCFCQKGFKIQSKLLKHKQIHTRNKAFR-----------ALLL 249
            +L +H+  H+ E+P++C  C K F   + L +HK+IHT  K ++             L 
Sbjct: 346 ANLYVHRRIHTGEKPYKCEDCGKAFGRYTALNQHKKIHTGEKPYKCEECGKAFNSSTNLT 405

Query: 250 KKRRTESRPLPNKLNANQGGFENGEIGESEENNPLDVHSIYIVPFQCPKCEKCFESEQIL 309
             +R  +R  P         F     G S   N          P++C +C K F     L
Sbjct: 406 AHKRIHTREKPYTCEDRGRAF-----GLSTNLNEYKKIHTGDKPYKCKECGKAFIHSLHL 460

Query: 310 NEHSCFAARSGKIPSRFKRSYNYKTIVKKILAKLKRARSKKLDNFQSEKKVFK--KSFLR 367
           N+H      +GK P      Y  K   K I +    A+ K++   +   +  +  K+F  
Sbjct: 461 NKHE--KIHTGKKP------YKCKQCGKVITSSSSFAKHKRIHTGEKPFECLECGKAFTS 512

Query: 368 NCDLISGEQSSEQTQRTFVGSLGKHGTYKTI--GNRKKKTLTLPFSWQNMGKNLKGILTT 425
           +  L    +     +       GK      I   +R+  T   P++ +  GK  +     
Sbjct: 513 STTLTKHRRIHTGEKPYTCEVCGKAFRQSAILYVHRRIHTGEKPYTCEECGKTFRQSANL 572

Query: 426 ENILSIDNSVNKKDLSICGS---------------SGEEFFNNCEVLQCGFSV------- 463
                I           CG                +GE+ +  CE  +CG          
Sbjct: 573 YVHRRIHTGEKPYKCEECGKAFGRYTDLNQHKKIHTGEKLY-KCE--ECGKDFVWYTDLN 629

Query: 464 PRENIRTRHKICPCDKCEKVFPSISKLKRHYLIHTGQRPFGCNICGKSFRQSAHLKRHEQ 523
            ++ I T  K   C++C K F   + L +H  I TG++ + C  CGK+F  S  L +H++
Sbjct: 630 QQKKIYTGEKPYKCEECGKAFAPSTDLNQHTKILTGEQSYKCEECGKAFGWSIALNQHKK 689

Query: 524 THNEKSPY-ASLCQVEFGNFNNLSNHSGNNVNYNASQQCQAPGVQKYEVSESDQMSGVKA 582
            H  + PY    C   F    NL+ H   +              + Y+  +  +  G   
Sbjct: 690 IHTGEKPYKCEECGKAFSRSRNLTTHRRVHTR-----------EKPYKCEDRGRSFGWST 738

Query: 583 ESQDFIPGSTGQPCLPNVLLESEQSNPFCSYSEHQEKNDVF-----LYRCSVCAKSFRSP 637
              ++    TG     + L + ++       S H  +++        Y+C  C K   S 
Sbjct: 739 NLNEYKKIHTG-----DKLYKCKECGKVFKQSSHLNRHEKIHTGKKPYKCKECGKVITSS 793

Query: 638 SKLERHYLIHAGQKPFECSVCGKTFRQAPHWKRHQLTHFKERP 680
           S   +H  IH G+KPF+C  CGK F  +    +H+  H  E+P
Sbjct: 794 SSFAKHKRIHTGEKPFKCLECGKAFTSSTTLTKHRRIHTGEKP 836



 Score =  167 bits (424), Expect = 2e-41
 Identities = 144/538 (26%), Positives = 222/538 (41%), Gaps = 70/538 (13%)

Query: 23  RNRPYVCNICFKHFETPSKLARHYLIHTGQKPFECDVCHKTFRQLVHLERHQLTHS--LP 80
           R +PY C    + F   + L  +  IHTG KP++C  C K F   +HL +H+  H+   P
Sbjct: 413 REKPYTCEDRGRAFGLSTNLNEYKKIHTGDKPYKCKECGKAFIHSLHLNKHEKIHTGKKP 472

Query: 81  FKCSICQRHFKNLKTFVKHQQLHNETYQNNVKQVRRLLEAKQEKSMYGVYNTFTTEERWA 140
           +KC  C +   +  +F KH+++H            +  E  +    +    T T   R  
Sbjct: 473 YKCKQCGKVITSSSSFAKHKRIHTG---------EKPFECLECGKAFTSSTTLTKHRR-- 521

Query: 141 LHPCSKSDPMYSMKRRKNIHACTICGKMFPSQSKLDRHVLIHTGQRPFKCVLCTKSFRQS 200
           +H   K             + C +CGK F   + L  H  IHTG++P+ C  C K+FRQS
Sbjct: 522 IHTGEKP------------YTCEVCGKAFRQSAILYVHRRIHTGEKPYTCEECGKTFRQS 569

Query: 201 THLKIHQLTHSEERPFQCCFCQKGFKIQSKLLKHKQIHTRNKAFRALLLKKRRTESRPL- 259
            +L +H+  H+ E+P++C  C K F   + L +HK+IHT  K ++     K       L 
Sbjct: 570 ANLYVHRRIHTGEKPYKCEECGKAFGRYTDLNQHKKIHTGEKLYKCEECGKDFVWYTDLN 629

Query: 260 -PNKLNANQGGFENGEIGES-EENNPLDVHSIYIVPFQCPKCEKC---FESEQILNEHSC 314
              K+   +  ++  E G++   +  L+ H+  +   Q  KCE+C   F     LN+H  
Sbjct: 630 QQKKIYTGEKPYKCEECGKAFAPSTDLNQHTKILTGEQSYKCEECGKAFGWSIALNQHK- 688

Query: 315 FAARSGKIPSR-------FKRSYNYKTIVKKILAKLK------RARSKKLD-NFQSEKKV 360
               +G+ P +       F RS N  T  +++  + K      R RS     N    KK+
Sbjct: 689 -KIHTGEKPYKCEECGKAFSRSRNLTTH-RRVHTREKPYKCEDRGRSFGWSTNLNEYKKI 746

Query: 361 FKKSFLRNCDLISG--EQSSEQTQRTFVGSLGKHGTYKTIG-----------NRKKKTLT 407
                L  C       +QSS   +   + +  K    K  G           +++  T  
Sbjct: 747 HTGDKLYKCKECGKVFKQSSHLNRHEKIHTGKKPYKCKECGKVITSSSSFAKHKRIHTGE 806

Query: 408 LPFSWQNMGKNLKGILTTENILSIDNSVNKKDLSICGSSGEEFFNNCEVLQCGFSVPREN 467
            PF     GK      T      I           CG +    F    +L          
Sbjct: 807 KPFKCLECGKAFTSSTTLTKHRRIHTGEKPYTCEECGKA----FRQSAILYV-----HRR 857

Query: 468 IRTRHKICPCDKCEKVFPSISKLKRHYLIHTGQRPFGCNICGKSFRQSAHLKRHEQTH 525
           I T  K   C +C K F   + L  H  IHTG++P+ C  CGK+FRQSA+L  H++ H
Sbjct: 858 IHTGEKPYTCGECGKTFRQSANLYAHKKIHTGEKPYTCGDCGKTFRQSANLYAHKKIH 915



 Score =  155 bits (391), Expect = 2e-37
 Identities = 150/598 (25%), Positives = 239/598 (39%), Gaps = 111/598 (18%)

Query: 121 KQEKSMYGVYNTFTTEERWALHPCSKSDPMYSM----KRRKNIHA------CTICGKMFP 170
           K +K +Y   N   +  +  +  C+    ++S      + K  H       C  CGK F 
Sbjct: 60  KVQKGVYNGINKCLSNTQSKIFQCNARVKVFSKFANSNKDKTRHTGEKHFKCNECGKSFQ 119

Query: 171 SQSKLDRHVLIHTGQRPFKCVLCTKSFRQSTHLKIHQLTHSEERPFQCCFCQKGFKIQSK 230
             S L +H  IH G++P+ C    K F   T L  H+  H+ E+P++C  C K F   + 
Sbjct: 120 KFSDLTQHKGIHAGEKPYTCEERGKDFGWYTDLNQHKKIHTGEKPYKCEECGKAFNRSTN 179

Query: 231 LLKHKQIHTRNKAFRALLLKKRRTESRPLPNKLNANQGGFENGEIGESEENNPLDVHSIY 290
           L  HK+IH R KA+          E R      + N   ++    G+             
Sbjct: 180 LTAHKRIHNREKAYTG--------EDRDRAFGWSTNLNEYKKIHTGDK------------ 219

Query: 291 IVPFQCPKCEKCFESEQILNEHSCFAARSGKIPSRFKRSYNYKTIVKKILAKLKRARSKK 350
             P++C +C K F     LN+H      +G+ P      Y  K   K I +    A+ K+
Sbjct: 220 --PYKCKECGKAFMHSSHLNKHE--KIHTGEKP------YKCKECGKVISSSSSFAKHKR 269

Query: 351 LDNFQSEKKVFKKSFLRNCDLISGEQSSEQTQRTFVGSLGKHGTYKTIGNRKKKTLTLPF 410
           +    + +K FK      C L  G+  +  T      +L KH        R+  T   P+
Sbjct: 270 I---HTGEKPFK------C-LECGKAFNIST------TLTKH--------RRIHTGEKPY 305

Query: 411 SWQNMGKNLKGILTTENILSIDNSVNKKDLSICGSSGEEFFNNCEVLQCGFSVPRENIRT 470
           + +  GK  +    + N+         +    CG  G+ F  +  +           I T
Sbjct: 306 TCEVCGKAFR---QSANLYVHRRIHTGEKPYTCGECGKTFRQSANL------YVHRRIHT 356

Query: 471 RHKICPCDKCEKVFPSISKLKRHYLIHTGQRPFGCNICGKSFRQSAHLKRHEQTHNEKSP 530
             K   C+ C K F   + L +H  IHTG++P+ C  CGK+F  S +L  H++ H  + P
Sbjct: 357 GEKPYKCEDCGKAFGRYTALNQHKKIHTGEKPYKCEECGKAFNSSTNLTAHKRIHTREKP 416

Query: 531 YASLCQVE---FGNFNNLSN----HSG--------------NNVNYNASQQCQAPGVQKY 569
           Y   C+     FG   NL+     H+G              ++++ N  ++    G + Y
Sbjct: 417 YT--CEDRGRAFGLSTNLNEYKKIHTGDKPYKCKECGKAFIHSLHLNKHEKIHT-GKKPY 473

Query: 570 EVSESDQM---SGVKAESQDFIPGSTGQPCLPNVLLESEQSNPFCSYSEHQEKNDVFL-- 624
           +  +  ++   S   A+ +    G     CL       E    F S +   +   +    
Sbjct: 474 KCKQCGKVITSSSSFAKHKRIHTGEKPFECL-------ECGKAFTSSTTLTKHRRIHTGE 526

Query: 625 --YRCSVCAKSFRSPSKLERHYLIHAGQKPFECSVCGKTFRQAPHWKRHQLTHFKERP 680
             Y C VC K+FR  + L  H  IH G+KP+ C  CGKTFRQ+ +   H+  H  E+P
Sbjct: 527 KPYTCEVCGKAFRQSAILYVHRRIHTGEKPYTCEECGKTFRQSANLYVHRRIHTGEKP 584



 Score =  145 bits (365), Expect = 2e-34
 Identities = 128/493 (25%), Positives = 209/493 (42%), Gaps = 60/493 (12%)

Query: 25  RPYVCNICFKHFETPSKLARHYLIHTGQKPFECDVCHKTFRQLVHLERHQLTHS--LPFK 82
           +PY C  C K   + S  A+H  IHTG+KPFEC  C K F     L +H+  H+   P+ 
Sbjct: 471 KPYKCKQCGKVITSSSSFAKHKRIHTGEKPFECLECGKAFTSSTTLTKHRRIHTGEKPYT 530

Query: 83  CSICQRHFKNLKTFVKHQQLHNETYQNNVKQVRRLLEAKQEKSMYGVYNTFTTEERWALH 142
           C +C + F+       H+++H        ++  +    +Q  ++Y      T E+ +   
Sbjct: 531 CEVCGKAFRQSAILYVHRRIHTGEKPYTCEECGKTF--RQSANLYVHRRIHTGEKPYKCE 588

Query: 143 PCSKSDPMYS-MKRRKNIHA------CTICGKMFPSQSKLDRHVLIHTGQRPFKCVLCTK 195
            C K+   Y+ + + K IH       C  CGK F   + L++   I+TG++P+KC  C K
Sbjct: 589 ECGKAFGRYTDLNQHKKIHTGEKLYKCEECGKDFVWYTDLNQQKKIYTGEKPYKCEECGK 648

Query: 196 SFRQSTHLKIHQLTHSEERPFQCCFCQKGFKIQSKLLKHKQIHTRNKAFRALLLKKRRTE 255
           +F  ST L  H    + E+ ++C  C K F     L +HK+IHT  K ++     K  + 
Sbjct: 649 AFAPSTDLNQHTKILTGEQSYKCEECGKAFGWSIALNQHKKIHTGEKPYKCEECGKAFSR 708

Query: 256 SRPLPN--KLNANQGGFENGEIGESE--ENNPLDVHSIYIVP--FQCPKCEKCFESEQIL 309
           SR L    +++  +  ++  + G S     N  +   I+     ++C +C K F+    L
Sbjct: 709 SRNLTTHRRVHTREKPYKCEDRGRSFGWSTNLNEYKKIHTGDKLYKCKECGKVFKQSSHL 768

Query: 310 NEHSCFAARSGKIPSRFKRSYNYKTIVKKILAKLKRARSKKLDNFQSEKKVFKKSFLRNC 369
           N H      +GK P      Y  K   K I +    A+ K++    + +K FK      C
Sbjct: 769 NRHE--KIHTGKKP------YKCKECGKVITSSSSFAKHKRI---HTGEKPFK------C 811

Query: 370 DLISGEQSSEQTQRTFVGSLGKHGTYKTIGNRKKKTLTLPFSWQNMGKNLKGILTTENIL 429
            L  G+  +  T      +L KH        R+  T   P++ +  GK  +       IL
Sbjct: 812 -LECGKAFTSST------TLTKH--------RRIHTGEKPYTCEECGKAFR----QSAIL 852

Query: 430 SIDNSVNKKDLSI-CGSSGEEFFNNCEVLQCGFSVPRENIRTRHKICPCDKCEKVFPSIS 488
            +   ++  +    CG  G+ F  +  +         + I T  K   C  C K F   +
Sbjct: 853 YVHRRIHTGEKPYTCGECGKTFRQSANLYA------HKKIHTGEKPYTCGDCGKTFRQSA 906

Query: 489 KLKRHYLIHTGQR 501
            L  H  IHTG +
Sbjct: 907 NLYAHKKIHTGDK 919



 Score =  123 bits (309), Expect = 5e-28
 Identities = 73/233 (31%), Positives = 112/233 (48%), Gaps = 11/233 (4%)

Query: 21  LPRNRPYVCNICFKHFETPSKLARHYLIHTGQKPFECDVCHKTFRQLVHLERHQLTHSL- 79
           L   + Y C  C K F     L +H  IHTG+KP++C+ C K F +  +L  H+  H+  
Sbjct: 663 LTGEQSYKCEECGKAFGWSIALNQHKKIHTGEKPYKCEECGKAFSRSRNLTTHRRVHTRE 722

Query: 80  -PFKCSICQRHFKNLKTFVKHQQLHNETYQNNVKQVRRLLEAKQEKSMYGVYNTFTTEER 138
            P+KC    R F       +++++H        K+  ++   KQ   +       T ++ 
Sbjct: 723 KPYKCEDRGRSFGWSTNLNEYKKIHTGDKLYKCKECGKVF--KQSSHLNRHEKIHTGKKP 780

Query: 139 WALHPCSKS-DPMYSMKRRKNIHA------CTICGKMFPSQSKLDRHVLIHTGQRPFKCV 191
           +    C K      S  + K IH       C  CGK F S + L +H  IHTG++P+ C 
Sbjct: 781 YKCKECGKVITSSSSFAKHKRIHTGEKPFKCLECGKAFTSSTTLTKHRRIHTGEKPYTCE 840

Query: 192 LCTKSFRQSTHLKIHQLTHSEERPFQCCFCQKGFKIQSKLLKHKQIHTRNKAF 244
            C K+FRQS  L +H+  H+ E+P+ C  C K F+  + L  HK+IHT  K +
Sbjct: 841 ECGKAFRQSAILYVHRRIHTGEKPYTCGECGKTFRQSANLYAHKKIHTGEKPY 893



 Score =  120 bits (300), Expect = 6e-27
 Identities = 70/232 (30%), Positives = 108/232 (46%), Gaps = 39/232 (16%)

Query: 23  RNRPYVCNICFKHFETPSKLARHYLIHTGQKPFECDVCHKTFRQLVHLERHQLTHS--LP 80
           R +PY C    + F   + L  +  IHTG K ++C  C K F+Q  HL RH+  H+   P
Sbjct: 721 REKPYKCEDRGRSFGWSTNLNEYKKIHTGDKLYKCKECGKVFKQSSHLNRHEKIHTGKKP 780

Query: 81  FKCSICQRHFKNLKTFVKHQQLHNETYQNNVKQVRRLLEAKQEKSMYGVYNTFTTEERWA 140
           +KC  C +   +  +F KH+++H                              T E+ + 
Sbjct: 781 YKCKECGKVITSSSSFAKHKRIH------------------------------TGEKPFK 810

Query: 141 LHPCSKS-DPMYSMKRRKNIHA------CTICGKMFPSQSKLDRHVLIHTGQRPFKCVLC 193
              C K+     ++ + + IH       C  CGK F   + L  H  IHTG++P+ C  C
Sbjct: 811 CLECGKAFTSSTTLTKHRRIHTGEKPYTCEECGKAFRQSAILYVHRRIHTGEKPYTCGEC 870

Query: 194 TKSFRQSTHLKIHQLTHSEERPFQCCFCQKGFKIQSKLLKHKQIHTRNKAFR 245
            K+FRQS +L  H+  H+ E+P+ C  C K F+  + L  HK+IHT +K  +
Sbjct: 871 GKTFRQSANLYAHKKIHTGEKPYTCGDCGKTFRQSANLYAHKKIHTGDKTIQ 922


>gi|150378520 zinc finger protein 594 [Homo sapiens]
          Length = 807

 Score =  219 bits (557), Expect = 9e-57
 Identities = 171/653 (26%), Positives = 276/653 (42%), Gaps = 104/653 (15%)

Query: 23  RNRPYVCNICFKHFETPSKLARHYLIHTGQKPFECDVCHKTFRQLVHLERHQLTHS--LP 80
           R +PY+CN C K F   + L  H+ IHTG+KP+EC  C + F Q  HL  HQ  H+   P
Sbjct: 235 RGKPYLCNKCGKAFSQSTDLIIHHRIHTGEKPYECYDCGQMFSQSSHLVPHQRIHTGEKP 294

Query: 81  FKCSICQRHFKNLKTFVKHQQLHNETYQNNVKQVRRLLEAKQEKSMYGVYNTFTTEERWA 140
            KC+ C++ F+      +HQ+LH+        +  R  +    ++ +  +      E+  
Sbjct: 295 LKCNECEKAFRQHSHLTEHQRLHS---GEKPYECHRCGKTFSGRTAFLKHQRLHAGEK-- 349

Query: 141 LHPCSKS-DPMYSMKRRKNIHA------CTICGKMFPSQSKLDRHVLIHTGQRPFKCVLC 193
           +  C K+      ++  + IH       C  CG+ F   S L RH + HTG++P++C  C
Sbjct: 350 IEECEKTFSKDEELREEQRIHQEEKAYWCNQCGRNFQGTSDLIRHQVTHTGEKPYECKEC 409

Query: 194 TKSFRQSTHLKIHQLTHSEERPFQCCFCQKGFKIQSKLLKHKQIHTRNKAFRALLLKKRR 253
            K+F QS+ L  H   HS E+P  C  C K F+  S L++H ++HT  K +      K  
Sbjct: 410 GKTFNQSSDLLRHHRIHSGEKPCVCSKCGKSFRGSSDLIRHHRVHTGEKPYECSECGKAF 469

Query: 254 TESRPLPNKLNANQGGFENGEIGESEENNPLDVHSIYIVPFQCPKCEKCFESEQILNEHS 313
           ++   L      + G                        P+QC +C K F    +L +H 
Sbjct: 470 SQRSHLVTHQKIHTGE----------------------KPYQCTECGKAFRRRSLLIQHR 507

Query: 314 CFAARSGKIPSRFKRSYNYKTIVKKILAKLKRARSKKLDNFQSEKKVFKKSFLRNCDLIS 373
                SG+ P      Y  K   K  + +    + + L     EK   +K+F ++ +L  
Sbjct: 508 --RIHSGEKP------YECKECGKLFIWRTAFLKHQSLHT--GEKLECEKTFSQDEEL-R 556

Query: 374 GEQSSEQTQRTFVGSLGKHGTYKTIGNRKKKTLTLPFSWQNM-GKNLKGILTTENILSID 432
           GEQ   Q  + +                          W N  G+  +G   + +++   
Sbjct: 557 GEQKIHQEAKAY--------------------------WCNQCGRAFQG---SSDLIRHQ 587

Query: 433 NSVNKKDLSICGSSGEEFFNNCEVLQCGFSVPRENIRTRHKICPCDKCEKVFPSISKLKR 492
            +  ++    C   G+ F  + ++L+         I +  K   C+KC K F   S L +
Sbjct: 588 VTHTREKPYECKECGKTFNQSSDLLR------HHRIHSGEKPYVCNKCGKSFRGSSDLIK 641

Query: 493 HYLIHTGQRPFGCNICGKSFRQSAHLKRHEQTHNEKSPY-ASLCQVEFGNFNNLSNHSGN 551
           H+ IHTG++P+ C+ CGK+F Q +HL  H++ H  + PY  S C   F   + L  H   
Sbjct: 642 HHRIHTGEKPYECSECGKAFSQRSHLATHQKIHTGEKPYQCSECGNAFRRRSLLIQHRRL 701

Query: 552 NVNYNASQQCQAPGVQKYEVSESDQM---SGVKAESQDFIPGSTGQPCLPNVLLESEQSN 608
           +            G + YE  E  ++        + Q    G   + C      + E   
Sbjct: 702 H-----------SGEKPYECKECGKLFMWHTAFLKHQRLHAGEKLEECEKTFSKDEELRK 750

Query: 609 PFCSYSEHQEKNDVFLYRCSVCAKSFRSPSKLERHYLIHAGQKPFECSVCGKT 661
                  HQEK    +Y C+ C+++F+  S L RH + H  +KP+EC  CGKT
Sbjct: 751 ---EQRTHQEKK---VYWCNQCSRTFQGSSDLIRHQVTHTREKPYECKECGKT 797



 Score =  209 bits (532), Expect = 7e-54
 Identities = 175/677 (25%), Positives = 279/677 (41%), Gaps = 115/677 (16%)

Query: 24  NRPYVCNICFKHFETPSKLARHYLIHTGQKPFECDVCHKTFRQLVHLERHQLTHS--LPF 81
           N+PYVCN C K     S L  H  IHTG+KP+ C  C K F Q  +L RH+  HS   P+
Sbjct: 152 NKPYVCNECGKDSNQSSNLIIHQRIHTGKKPYICHECGKDFNQSSNLVRHKQIHSGGNPY 211

Query: 82  KCSICQRHFKNLKTFVKHQQLHNETYQNNVKQVRRLLEAKQEKSMYGVYNTFTTEERWAL 141
           +C  C + FK     V HQ++H+                                 R   
Sbjct: 212 ECKECGKAFKGSSNLVLHQRIHS---------------------------------RGKP 238

Query: 142 HPCSKSDPMYSMKRRKNIH----------ACTICGKMFPSQSKLDRHVLIHTGQRPFKCV 191
           + C+K    +S      IH           C  CG+MF   S L  H  IHTG++P KC 
Sbjct: 239 YLCNKCGKAFSQSTDLIIHHRIHTGEKPYECYDCGQMFSQSSHLVPHQRIHTGEKPLKCN 298

Query: 192 LCTKSFRQSTHLKIHQLTHSEERPFQCCFCQKGFKIQSKLLKHKQIHTRNKAFRALLLKK 251
            C K+FRQ +HL  HQ  HS E+P++C  C K F  ++  LKH+++H   K         
Sbjct: 299 ECEKAFRQHSHLTEHQRLHSGEKPYECHRCGKTFSGRTAFLKHQRLHAGEKIEECEKTFS 358

Query: 252 RRTESRPLPNKLNANQGGFENGEIGES-EENNPLDVHSIYIV---PFQCPKCEKCF-ESE 306
           +  E R    +++  +  +   + G + +  + L  H +      P++C +C K F +S 
Sbjct: 359 KDEELRE-EQRIHQEEKAYWCNQCGRNFQGTSDLIRHQVTHTGEKPYECKECGKTFNQSS 417

Query: 307 QILNEHSCFAARSGKIPSRFKRSYNYKTIVKKILAKLKRARSKKLDNFQSEKKVFKKSFL 366
            +L  H   +     + S+  +S+   + +  I         K  +  +  K   ++S L
Sbjct: 418 DLLRHHRIHSGEKPCVCSKCGKSFRGSSDL--IRHHRVHTGEKPYECSECGKAFSQRSHL 475

Query: 367 RNCDLI-SGEQSSEQTQRTFVGSLGKHGTYKT--IGNRKKKTLTLPFSWQNMGKNLKGIL 423
                I +GE+  + T+       GK    ++  I +R+  +   P+  +  GK    + 
Sbjct: 476 VTHQKIHTGEKPYQCTE------CGKAFRRRSLLIQHRRIHSGEKPYECKECGK----LF 525

Query: 424 TTENILSIDNSVNKKDLSICGSSGEEFFNNCEVLQCGFSVPRENIRTRHKICPCDKCEKV 483
                     S++  +   C    E+ F+  E L+       + I    K   C++C + 
Sbjct: 526 IWRTAFLKHQSLHTGEKLEC----EKTFSQDEELR-----GEQKIHQEAKAYWCNQCGRA 576

Query: 484 FPSISKLKRHYLIHTGQRPFGCNICGKSFRQSAHLKRHEQTHNEKSPY-ASLCQVEFGNF 542
           F   S L RH + HT ++P+ C  CGK+F QS+ L RH + H+ + PY  + C   F   
Sbjct: 577 FQGSSDLIRHQVTHTREKPYECKECGKTFNQSSDLLRHHRIHSGEKPYVCNKCGKSFRGS 636

Query: 543 NNLSNHSGNNVNYNASQQCQAPGVQKYEVSESDQMSGVKAESQDFIPGSTGQPCLPNVLL 602
           ++L  H   +            G + YE SE  +    ++         TG+        
Sbjct: 637 SDLIKHHRIHT-----------GEKPYECSECGKAFSQRSHLATHQKIHTGEK------- 678

Query: 603 ESEQSNPFCSYSEHQEKNDVFLYRCSVCAKSFRSPSKLERHYLIHAGQKPFECSVCGKTF 662
                                 Y+CS C  +FR  S L +H  +H+G+KP+EC  CGK F
Sbjct: 679 ---------------------PYQCSECGNAFRRRSLLIQHRRLHSGEKPYECKECGKLF 717

Query: 663 RQAPHWKRHQLTHFKER 679
                + +HQ  H  E+
Sbjct: 718 MWHTAFLKHQRLHAGEK 734



 Score =  192 bits (488), Expect = 9e-49
 Identities = 163/666 (24%), Positives = 265/666 (39%), Gaps = 109/666 (16%)

Query: 47  LIHTGQKPFECDVCHKTFRQLVHLERHQLTHSL--PFKCSICQRHFKNLKTFVKHQQLHN 104
           ++  G+     +V  + F+Q   L  HQ  H++   ++C  C++ F      + HQ++H 
Sbjct: 91  ILSAGESSHRYEVSGQNFKQKSGLTEHQKIHNINKTYECKECEKTFNRSSNLIIHQRIHT 150

Query: 105 ETYQNNVKQVRRLLEAKQEKSMYGVYNTFTTEERWALHPCSKS-DPMYSMKRRKNIHA-- 161
                   +  +  ++ Q  ++       T ++ +  H C K  +   ++ R K IH+  
Sbjct: 151 GNKPYVCNECGK--DSNQSSNLIIHQRIHTGKKPYICHECGKDFNQSSNLVRHKQIHSGG 208

Query: 162 ----CTICGKMFPSQSKLDRHVLIHTGQRPFKCVLCTKSFRQSTHLKIHQLTHSEERPFQ 217
               C  CGK F   S L  H  IH+  +P+ C  C K+F QST L IH   H+ E+P++
Sbjct: 209 NPYECKECGKAFKGSSNLVLHQRIHSRGKPYLCNKCGKAFSQSTDLIIHHRIHTGEKPYE 268

Query: 218 CCFCQKGFKIQSKLLKHKQIHTRNKAFRALLLKKRRTESRPLPNKLNANQGGFENGEIGE 277
           C  C + F   S L+ H++IHT  K                                   
Sbjct: 269 CYDCGQMFSQSSHLVPHQRIHTGEK----------------------------------- 293

Query: 278 SEENNPLDVHSIYIVPFQCPKCEKCFESEQILNEHSCFAARSGKIP---SRFKRSYNYKT 334
                          P +C +CEK F     L EH      SG+ P    R  ++++ +T
Sbjct: 294 ---------------PLKCNECEKAFRQHSHLTEHQ--RLHSGEKPYECHRCGKTFSGRT 336

Query: 335 IVKKILAKLKRARSKKLDNFQSEKKVFKKSFLRNCDLISGEQSSEQTQRTF-VGSLGKH- 392
                 A LK  R    +  +  +K F K      + +  EQ   Q ++ +     G++ 
Sbjct: 337 ------AFLKHQRLHAGEKIEECEKTFSKD-----EELREEQRIHQEEKAYWCNQCGRNF 385

Query: 393 -GTYKTIGNRKKKTLTLPFSWQNMGKNLKGILTTENILSIDNSVNKKDLSICGSSGEEFF 451
            GT   I ++   T   P+  +  GK       + ++L      + +   +C   G+ F 
Sbjct: 386 QGTSDLIRHQVTHTGEKPYECKECGKTFN---QSSDLLRHHRIHSGEKPCVCSKCGKSFR 442

Query: 452 NNCEVLQCGFSVPRENIRTRHKICPCDKCEKVFPSISKLKRHYLIHTGQRPFGCNICGKS 511
            + ++++         + T  K   C +C K F   S L  H  IHTG++P+ C  CGK+
Sbjct: 443 GSSDLIR------HHRVHTGEKPYECSECGKAFSQRSHLVTHQKIHTGEKPYQCTECGKA 496

Query: 512 FRQSAHLKRHEQTHNEKSPY-----ASLCQVEFGNFNNLSNHSGNNVNYNA--SQQCQAP 564
           FR+ + L +H + H+ + PY       L         + S H+G  +      SQ  +  
Sbjct: 497 FRRRSLLIQHRRIHSGEKPYECKECGKLFIWRTAFLKHQSLHTGEKLECEKTFSQDEELR 556

Query: 565 GVQKYEVSES----DQMSGVKAESQDFIPGSTGQP------CLPNVLLESEQSNPFCSYS 614
           G QK          +Q       S D I             C       ++ S+    + 
Sbjct: 557 GEQKIHQEAKAYWCNQCGRAFQGSSDLIRHQVTHTREKPYECKECGKTFNQSSDLLRHHR 616

Query: 615 EHQEKNDVFLYRCSVCAKSFRSPSKLERHYLIHAGQKPFECSVCGKTFRQAPHWKRHQLT 674
            H  +     Y C+ C KSFR  S L +H+ IH G+KP+ECS CGK F Q  H   HQ  
Sbjct: 617 IHSGEKP---YVCNKCGKSFRGSSDLIKHHRIHTGEKPYECSECGKAFSQRSHLATHQKI 673

Query: 675 HFKERP 680
           H  E+P
Sbjct: 674 HTGEKP 679



 Score =  116 bits (291), Expect = 6e-26
 Identities = 68/243 (27%), Positives = 113/243 (46%), Gaps = 14/243 (5%)

Query: 25  RPYVCNICFKHFETPSKLARHYLIHTGQKPFECDVCHKTFRQLVHLERHQLTHS--LPFK 82
           + Y CN C + F+  S L RH + HT +KP+EC  C KTF Q   L RH   HS   P+ 
Sbjct: 566 KAYWCNQCGRAFQGSSDLIRHQVTHTREKPYECKECGKTFNQSSDLLRHHRIHSGEKPYV 625

Query: 83  CSICQRHFKNLKTFVKHQQLHNETYQNNVKQVRRLLEAKQEKSMYGVYNTFTTEERWALH 142
           C+ C + F+     +KH ++H         +  +    +   + +      T E+ +   
Sbjct: 626 CNKCGKSFRGSSDLIKHHRIHTGEKPYECSECGKAFSQRSHLATH--QKIHTGEKPYQCS 683

Query: 143 PCSKSDPMYSMK-RRKNIHA------CTICGKMFPSQSKLDRHVLIHTGQRPFKCVLCTK 195
            C  +    S+  + + +H+      C  CGK+F   +   +H  +H G+   K   C K
Sbjct: 684 ECGNAFRRRSLLIQHRRLHSGEKPYECKECGKLFMWHTAFLKHQRLHAGE---KLEECEK 740

Query: 196 SFRQSTHLKIHQLTHSEERPFQCCFCQKGFKIQSKLLKHKQIHTRNKAFRALLLKKRRTE 255
           +F +   L+  Q TH E++ + C  C + F+  S L++H+  HTR K +      K ++E
Sbjct: 741 TFSKDEELRKEQRTHQEKKVYWCNQCSRTFQGSSDLIRHQVTHTREKPYECKECGKTQSE 800

Query: 256 SRP 258
            RP
Sbjct: 801 LRP 803


>gi|6005976 zinc finger protein 208 [Homo sapiens]
          Length = 1167

 Score =  218 bits (555), Expect = 1e-56
 Identities = 179/686 (26%), Positives = 294/686 (42%), Gaps = 70/686 (10%)

Query: 25  RPYVCNICFKHFETPSKLARHYLIHTGQKPFECDVCHKTFRQLVHLERHQLTHS--LPFK 82
           + Y C  C K F   + L +H +IHTG+KP +C+ C K F ++  L  H+  H+   P+K
Sbjct: 255 KSYKCEECGKAFNQSAILTKHKIIHTGEKPNKCEECGKAFSKVSTLTTHKAIHAGEKPYK 314

Query: 83  CSICQRHFKNLKTFVKHQQLHNETYQNNVKQVRRLLEAKQEKSMYGVYNTFTTEERWALH 142
           C  C + F  + T + H+ +H        K+  +        + + V +T   E+ +   
Sbjct: 315 CKECGKAFSKVSTLITHKAIHAGEKPYKCKECGKAFSKFSILTKHKVIHT--GEKPYKCE 372

Query: 143 PCSKSDPMYS-MKRRKNIHA------CTICGKMFPSQSKLDRHVLIHTGQRPFKCVLCTK 195
            C K+    S +   K IH       C  CGK F   S L +H +IHTG++P+KC  C K
Sbjct: 373 ECGKAYKWPSTLSYHKKIHTGEKPYKCEECGKGFSMFSILTKHEVIHTGEKPYKCEECGK 432

Query: 196 SFRQSTHLKIHQLTHSEERPFQCCFCQKGFKIQSKLLKHKQIHTRNKAFRALLLKKRRTE 255
           +F  S++L  H+  H+ E P++C  C KGF   S L  HK+IHT  K ++     K   +
Sbjct: 433 AFNWSSNLMEHKKIHTGETPYKCEECGKGFSWSSTLSYHKKIHTVEKPYKCEECGKAFNQ 492

Query: 256 SRPL--PNKLNANQGGFENGEIGES-EENNPLDVHSIYIV---PFQCPKCEKCFESEQIL 309
           S  L    +++  +  ++  E G++  + + L  H        P++C +C K F     L
Sbjct: 493 SAILIKHKRIHTGEKPYKCEECGKTFSKVSTLTTHKAIHAGEKPYKCKECGKTFIKVSTL 552

Query: 310 NEHSCFAA--------RSGKIPSRFKRSYNYKTIVKKILAKLKRARSKKLDNFQSEKKVF 361
             H    A          GK  S+F     +K ++       K     K  N+ S     
Sbjct: 553 TTHKAIHAGEKPYKCKECGKAFSKFSILTKHK-VIHTGEKPYKCEECGKAFNWSSNLMEH 611

Query: 362 KKSFLRNCDLISGEQ--SSEQTQRTF--VGSLGKHGTYKTIGNRKKKTLTLPFSWQNMGK 417
           K+       + +GE+    E+  ++F     L KH   K I   +K     P+  +  GK
Sbjct: 612 KR-------IHTGEKPYKCEECGKSFSTFSVLTKH---KVIHTGEK-----PYKCEECGK 656

Query: 418 NLKGILTTENILSIDNSVNKKDLSICGSSGEEFFNNCEVLQCGFSVPRENIRTRHKICPC 477
             K   T      I           CG +    FN   +L     +  + I T  K   C
Sbjct: 657 AYKWSSTLSYHKKIHTVEKPYKCEECGKA----FNRSAIL-----IKHKRIHTDEKPYKC 707

Query: 478 DKCEKVFPSISKLKRHYLIHTGQRPFGCNICGKSFRQSAHLKRHEQTHNEKSPY-ASLCQ 536
           ++C K F  +S L  H  IH G++P+ C  CGK+F + + L +H+  H  + PY    C 
Sbjct: 708 EECGKTFSKVSTLTTHKAIHAGEKPYKCKECGKAFSKFSILTKHKVIHTGEKPYKCEECG 767

Query: 537 VEFGNFNNLSNHSGNNVNYNASQQCQAPGVQKYEVSESDQMSGVKAESQDFIPGSTGQPC 596
             +   + LS H   +       +C+       E  +   M  +  + +    G     C
Sbjct: 768 KAYKWPSTLSYHKKIHTG-EKPYKCE-------ECGKGFSMFSILTKHEVIHTGEKPYKC 819

Query: 597 LPNVLLESEQSNPFCS-YSEHQEKN-DVFLYRCSVCAKSFRSPSKLERHYLIHAGQKPFE 654
                 E  ++  + S +S+H++ +     Y+C  C K++ + S L +H +IH G+KP++
Sbjct: 820 -----EECGKAFSWLSVFSKHKKTHAGEKFYKCEACGKAYNTFSILTKHKVIHTGEKPYK 874

Query: 655 CSVCGKTFRQAPHWKRHQLTHFKERP 680
           C  CGK F  + +   H+  H  E P
Sbjct: 875 CEECGKAFNWSSNLMEHKKIHTGETP 900



 Score =  218 bits (554), Expect = 2e-56
 Identities = 173/672 (25%), Positives = 293/672 (43%), Gaps = 98/672 (14%)

Query: 25  RPYVCNICFKHFETPSKLARHYLIHTGQKPFECDVCHKTFRQLVHLERHQLTHS--LPFK 82
           +PY C  C K F   S L +H +IHTG+K ++C+ C K F Q   L +H++ H+   P K
Sbjct: 227 KPYRCKECGKAFSKFSILTKHKVIHTGEKSYKCEECGKAFNQSAILTKHKIIHTGEKPNK 286

Query: 83  CSICQRHFKNLKTFVKHQQLHNETYQNNVKQVRRLLEAKQEKSMYGVYNTFTTEERWALH 142
           C  C + F  + T   H+ +H            +  + K+    +   +T  T +  A+H
Sbjct: 287 CEECGKAFSKVSTLTTHKAIHAG---------EKPYKCKECGKAFSKVSTLITHK--AIH 335

Query: 143 PCSKSDPMYSMKRRKNIHACTICGKMFPSQSKLDRHVLIHTGQRPFKCVLCTKSFRQSTH 202
              K             + C  CGK F   S L +H +IHTG++P+KC  C K+++  + 
Sbjct: 336 AGEKP------------YKCKECGKAFSKFSILTKHKVIHTGEKPYKCEECGKAYKWPST 383

Query: 203 LKIHQLTHSEERPFQCCFCQKGFKIQSKLLKHKQIHTRNKAFRALLLKKRRTESRPLPN- 261
           L  H+  H+ E+P++C  C KGF + S L KH+ IHT  K ++     K    S  L   
Sbjct: 384 LSYHKKIHTGEKPYKCEECGKGFSMFSILTKHEVIHTGEKPYKCEECGKAFNWSSNLMEH 443

Query: 262 -KLNANQGGFENGEIGESEE-NNPLDVHS-IYIV--PFQCPKCEKCFESEQILNEHSCFA 316
            K++  +  ++  E G+    ++ L  H  I+ V  P++C +C K F    IL +H    
Sbjct: 444 KKIHTGETPYKCEECGKGFSWSSTLSYHKKIHTVEKPYKCEECGKAFNQSAILIKHK--R 501

Query: 317 ARSGKIPSRFKRSYNYKTIVKKILAKLKRARSKKLDNFQSEKKVFKKSFLRNCDLISGEQ 376
             +G+ P + +          K  +K+    + K     + +K +K              
Sbjct: 502 IHTGEKPYKCEEC-------GKTFSKVSTLTTHKA--IHAGEKPYK-------------- 538

Query: 377 SSEQTQRTFVGSLGKHGTYKTIGNRKKKTLTLPFSWQNMGKNLK--GILTTENILSIDNS 434
             ++  +TF+  +    T+K I   +K     P+  +  GK      ILT   ++     
Sbjct: 539 -CKECGKTFI-KVSTLTTHKAIHAGEK-----PYKCKECGKAFSKFSILTKHKVIHTGEK 591

Query: 435 VNKKDLSICGSSGEEFFNNCEVLQCGFSVPRENIRTRHKICPCDKCEKVFPSISKLKRHY 494
             K     C   G+ F  +  +++       + I T  K   C++C K F + S L +H 
Sbjct: 592 PYK-----CEECGKAFNWSSNLME------HKRIHTGEKPYKCEECGKSFSTFSVLTKHK 640

Query: 495 LIHTGQRPFGCNICGKSFRQSAHLKRHEQTHNEKSPY-ASLCQVEFGNFNNLSNHSGNNV 553
           +IHTG++P+ C  CGK+++ S+ L  H++ H  + PY    C   F     L  H   + 
Sbjct: 641 VIHTGEKPYKCEECGKAYKWSSTLSYHKKIHTVEKPYKCEECGKAFNRSAILIKHKRIHT 700

Query: 554 NYNASQQCQAPGVQKYEVSESDQMSGVKAESQDFIPGSTGQPCLPNVLLESEQSNPFCSY 613
           +     +C+  G    +VS       + A  + +     G           +  + F   
Sbjct: 701 D-EKPYKCEECGKTFSKVSTLTTHKAIHAGEKPYKCKECG-----------KAFSKFSIL 748

Query: 614 SEHQ-----EKNDVFLYRCSVCAKSFRSPSKLERHYLIHAGQKPFECSVCGKTFRQAPHW 668
           ++H+     EK     Y+C  C K+++ PS L  H  IH G+KP++C  CGK F      
Sbjct: 749 TKHKVIHTGEKP----YKCEECGKAYKWPSTLSYHKKIHTGEKPYKCEECGKGFSMFSIL 804

Query: 669 KRHQLTHFKERP 680
            +H++ H  E+P
Sbjct: 805 TKHEVIHTGEKP 816



 Score =  216 bits (550), Expect = 6e-56
 Identities = 176/687 (25%), Positives = 289/687 (42%), Gaps = 100/687 (14%)

Query: 25  RPYVCNICFKHFETPSKLARHYLIHTGQKPFECDVCHKTFRQLVHLERHQLTHS--LPFK 82
           +PY C  C K ++ PS L+ H  IHTG+KP++C+ C K F     L +H++ H+   P+K
Sbjct: 367 KPYKCEECGKAYKWPSTLSYHKKIHTGEKPYKCEECGKGFSMFSILTKHEVIHTGEKPYK 426

Query: 83  CSICQRHFKNLKTFVKHQQLHNETYQNNVKQVRRLLEAKQEKSMYGVYNTFTTEERWALH 142
           C  C + F      ++H+++H        ++  +        S +   +T   E+ +   
Sbjct: 427 CEECGKAFNWSSNLMEHKKIHTGETPYKCEECGKGFSWSSTLSYHKKIHT--VEKPYKCE 484

Query: 143 PCSKS-DPMYSMKRRKNIHA------CTICGKMFPSQSKLDRHVLIHTGQRPFKCVLCTK 195
            C K+ +    + + K IH       C  CGK F   S L  H  IH G++P+KC  C K
Sbjct: 485 ECGKAFNQSAILIKHKRIHTGEKPYKCEECGKTFSKVSTLTTHKAIHAGEKPYKCKECGK 544

Query: 196 SFRQSTHLKIHQLTHSEERPFQCCFCQKGFKIQSKLLKHKQIHTRNKAFRALLLKKRRTE 255
           +F + + L  H+  H+ E+P++C  C K F   S L KHK IHT  K ++     K    
Sbjct: 545 TFIKVSTLTTHKAIHAGEKPYKCKECGKAFSKFSILTKHKVIHTGEKPYKCEECGKA--- 601

Query: 256 SRPLPNKLNANQGGFENGEIGESEENNPLDVHSIYIVPFQCPKCEKCFESEQILNEHSCF 315
                   N +    E+  I   E+            P++C +C K F +  +L +H   
Sbjct: 602 -------FNWSSNLMEHKRIHTGEK------------PYKCEECGKSFSTFSVLTKH--- 639

Query: 316 AARSGKIPSRFKRSYNYKTIVKKILAKLKRARSKKLDNFQSEKKVFK--KSFLRNCDLIS 373
                K+    ++ Y  +   K        +  KK+   +   K  +  K+F R+  LI 
Sbjct: 640 -----KVIHTGEKPYKCEECGKAYKWSSTLSYHKKIHTVEKPYKCEECGKAFNRSAILIK 694

Query: 374 GEQ--------SSEQTQRTFVGSLGKHGTYKTIGNRKKKTLTLPFSWQNMGKNLK--GIL 423
            ++          E+  +TF   +    T+K I   +K     P+  +  GK      IL
Sbjct: 695 HKRIHTDEKPYKCEECGKTF-SKVSTLTTHKAIHAGEK-----PYKCKECGKAFSKFSIL 748

Query: 424 TTENILSIDNSVNKKDLSICGSSGEEFFNNCEVLQCGFSVP-----RENIRTRHKICPCD 478
           T   ++                +GE+ +  CE     +  P      + I T  K   C+
Sbjct: 749 TKHKVIH---------------TGEKPYK-CEECGKAYKWPSTLSYHKKIHTGEKPYKCE 792

Query: 479 KCEKVFPSISKLKRHYLIHTGQRPFGCNICGKSFRQSAHLKRHEQTH-NEKSPYASLCQV 537
           +C K F   S L +H +IHTG++P+ C  CGK+F   +   +H++TH  EK      C  
Sbjct: 793 ECGKGFSMFSILTKHEVIHTGEKPYKCEECGKAFSWLSVFSKHKKTHAGEKFYKCEACGK 852

Query: 538 EFGNFNNLSNHSGNNVNYNASQQCQAPGVQKYEVSESDQMSGVKAESQDFIPGSTGQPCL 597
            +  F+ L+ H   +       +C+       E  ++   S    E +    G T   C 
Sbjct: 853 AYNTFSILTKHKVIHTG-EKPYKCE-------ECGKAFNWSSNLMEHKKIHTGETPYKC- 903

Query: 598 PNVLLESEQSNPFC---SYSEHQEKN-DVFLYRCSVCAKSFRSPSKLERHYLIHAGQKPF 653
                  E    F    S +EH+  +     Y+C  C K+F  PS+L  H   HAG++P+
Sbjct: 904 ------EECDKAFSWPSSLTEHKATHAGEKPYKCEECGKAFSWPSRLTEHKATHAGEEPY 957

Query: 654 ECSVCGKTFRQAPHWKRHQLTHFKERP 680
           +C  CGK F  + +   H+  H  E+P
Sbjct: 958 KCEECGKAFNWSSNLMEHKRIHTGEKP 984



 Score =  213 bits (543), Expect = 4e-55
 Identities = 176/697 (25%), Positives = 293/697 (42%), Gaps = 92/697 (13%)

Query: 25   RPYVCNICFKHFETPSKLARHYLIHTGQKPFECDVCHKTFRQLVHLERHQLTHS--LPFK 82
            +PY C  C K F   + L +H  IHTG+KP++C+ C KTF ++  L  H+  H+   P+K
Sbjct: 479  KPYKCEECGKAFNQSAILIKHKRIHTGEKPYKCEECGKTFSKVSTLTTHKAIHAGEKPYK 538

Query: 83   CSICQRHFKNLKTFVKHQQLHNETYQNNVKQVRRLLEAKQEKSMYGVYNTFTTEERWALH 142
            C  C + F  + T   H+ +H        K+  +        + + V +T   E+ +   
Sbjct: 539  CKECGKTFIKVSTLTTHKAIHAGEKPYKCKECGKAFSKFSILTKHKVIHT--GEKPYKCE 596

Query: 143  PCSKSDPMYS-MKRRKNIHA------CTICGKMFPSQSKLDRHVLIHTGQRPFKCVLCTK 195
             C K+    S +   K IH       C  CGK F + S L +H +IHTG++P+KC  C K
Sbjct: 597  ECGKAFNWSSNLMEHKRIHTGEKPYKCEECGKSFSTFSVLTKHKVIHTGEKPYKCEECGK 656

Query: 196  SFRQSTHLKIHQLTHSEERPFQCCFCQKGFKIQSKLLKHKQIHTRNKAFRALLLKKRRTE 255
            +++ S+ L  H+  H+ E+P++C  C K F   + L+KHK+IHT  K ++     K  ++
Sbjct: 657  AYKWSSTLSYHKKIHTVEKPYKCEECGKAFNRSAILIKHKRIHTDEKPYKCEECGKTFSK 716

Query: 256  SRPLPNKLNANQGGFENGEIGESEENNPLDVHSIYIVPFQCPKCEKCFESEQILNEHSCF 315
               L      + G                        P++C +C K F    IL +H   
Sbjct: 717  VSTLTTHKAIHAGE----------------------KPYKCKECGKAFSKFSILTKHKVI 754

Query: 316  AARSGKIPSRFK---RSYNYKTIV---KKILAKLKRARSKKLDNFQSEKKVFKKSFLRNC 369
               +G+ P + +   ++Y + + +   KKI    K  + ++     S   +  K  +   
Sbjct: 755  --HTGEKPYKCEECGKAYKWPSTLSYHKKIHTGEKPYKCEECGKGFSMFSILTKHEV--- 809

Query: 370  DLISGEQSSEQTQRTFVGSLGKHGTYKTIGNRKKKTLTLP--FSWQNMGK--NLKGILTT 425
             + +GE+  +  +       GK  ++ ++ ++ KKT      +  +  GK  N   ILT 
Sbjct: 810  -IHTGEKPYKCEE------CGKAFSWLSVFSKHKKTHAGEKFYKCEACGKAYNTFSILTK 862

Query: 426  ENILSIDNSVNKKDLSICGSSGEEFFN--------------NCEVLQCGFSVPRENIRTR 471
              ++       K +   CG +     N               CE     FS P     T 
Sbjct: 863  HKVIHTGEKPYKCEE--CGKAFNWSSNLMEHKKIHTGETPYKCEECDKAFSWPSS--LTE 918

Query: 472  HKIC-------PCDKCEKVFPSISKLKRHYLIHTGQRPFGCNICGKSFRQSAHLKRHEQT 524
            HK          C++C K F   S+L  H   H G+ P+ C  CGK+F  S++L  H++ 
Sbjct: 919  HKATHAGEKPYKCEECGKAFSWPSRLTEHKATHAGEEPYKCEECGKAFNWSSNLMEHKRI 978

Query: 525  HNEKSPY-ASLCQVEFGNFNNLSNHSGNNVNYNASQQCQAPGVQKYEVSESDQMSGVKAE 583
            H  + PY    C   F  F+ L+ H   +       +C+  G      S       +   
Sbjct: 979  HTGEKPYKCEECGKSFSTFSILTKHKVIHTG-EKPYKCEECGKAYKWSSTLSYHKKIHTV 1037

Query: 584  SQDFIPGSTGQPCLPNVLLESEQSNPFCSYSEHQEKNDVFLYRCSVCAKSFRSPSKLERH 643
             + +     G+  +   +L   +           EK    LY+C  C K+++ PS L  H
Sbjct: 1038 EKPYKCEECGKGFVMFSILAKHK------VIHTGEK----LYKCEECGKAYKWPSTLRYH 1087

Query: 644  YLIHAGQKPFECSVCGKTFRQAPHWKRHQLTHFKERP 680
              IH G+KP++C  CGK F       +H++ H  E+P
Sbjct: 1088 KKIHTGEKPYKCEECGKAFSTFSILTKHKVIHTGEKP 1124



 Score =  191 bits (486), Expect = 1e-48
 Identities = 166/668 (24%), Positives = 272/668 (40%), Gaps = 100/668 (14%)

Query: 25   RPYVCNICFKHFETPSKLARHYLIHTGQKPFECDVCHKTFRQLVHLERHQLTHS--LPFK 82
            +PY C  C K F   S L +H +IHTG+KP++C+ C K F    +L  H+  H+   P+K
Sbjct: 563  KPYKCKECGKAFSKFSILTKHKVIHTGEKPYKCEECGKAFNWSSNLMEHKRIHTGEKPYK 622

Query: 83   CSICQRHFKNLKTFVKHQQLHNETYQNNVKQVRRLLEAKQEKSMYGVYNTFTTEERWALH 142
            C  C + F       KH+ +H        ++  +  +     S +   +T   E+ +   
Sbjct: 623  CEECGKSFSTFSVLTKHKVIHTGEKPYKCEECGKAYKWSSTLSYHKKIHT--VEKPYKCE 680

Query: 143  PCSKS-DPMYSMKRRKNIHA------CTICGKMFPSQSKLDRHVLIHTGQRPFKCVLCTK 195
             C K+ +    + + K IH       C  CGK F   S L  H  IH G++P+KC  C K
Sbjct: 681  ECGKAFNRSAILIKHKRIHTDEKPYKCEECGKTFSKVSTLTTHKAIHAGEKPYKCKECGK 740

Query: 196  SFRQSTHLKIHQLTHSEERPFQCCFCQKGFKIQSKLLKHKQIHTRNKAFRALLLKKRRTE 255
            +F + + L  H++ H+ E+P++C  C K +K  S L  HK+IHT  K             
Sbjct: 741  AFSKFSILTKHKVIHTGEKPYKCEECGKAYKWPSTLSYHKKIHTGEK------------- 787

Query: 256  SRPLPNKLNANQGGFENGEIGESEENNPLDVHSIYIVPFQCPKCEKCFESEQILNEHS-C 314
                P K      GF    I    E     V      P++C +C K F    + ++H   
Sbjct: 788  ----PYKCEECGKGFSMFSILTKHE-----VIHTGEKPYKCEECGKAFSWLSVFSKHKKT 838

Query: 315  FAARSGKIPSRFKRSYNYKTIVKKILAKLKRARSKKLDNFQSEKKV-FKKSFLRNCDLIS 373
             A           ++YN  +I+ K   K+     K     +  K   +  + + +  + +
Sbjct: 839  HAGEKFYKCEACGKAYNTFSILTK--HKVIHTGEKPYKCEECGKAFNWSSNLMEHKKIHT 896

Query: 374  GEQ--SSEQTQRTFV--GSLGKH-GTYKTIGNRKKKTLTLPFSWQNMGKNLKGILTTENI 428
            GE     E+  + F    SL +H  T+      K +     FSW +        LT    
Sbjct: 897  GETPYKCEECDKAFSWPSSLTEHKATHAGEKPYKCEECGKAFSWPSR-------LTEHKA 949

Query: 429  LSIDNSVNKKDLSICGSSGEEFFNNCEVLQCGFSVPRENIRTRHKICPCDKCEKVFPSIS 488
                    K     C   G+ F  +  +++       + I T  K   C++C K F + S
Sbjct: 950  THAGEEPYK-----CEECGKAFNWSSNLME------HKRIHTGEKPYKCEECGKSFSTFS 998

Query: 489  KLKRHYLIHTGQRPFGCNICGKSFRQSAHLKRHEQTHNEKSPY-ASLCQVEFGNFNNLSN 547
             L +H +IHTG++P+ C  CGK+++ S+ L  H++ H  + PY    C   F  F+ L+ 
Sbjct: 999  ILTKHKVIHTGEKPYKCEECGKAYKWSSTLSYHKKIHTVEKPYKCEECGKGFVMFSILAK 1058

Query: 548  HSGNNVNYNASQQCQAPGVQKYEVSESDQMSGVKAESQDFIPGSTGQPCLPNVLLESEQS 607
            H   +            G + Y+  E  +     +  +      TG+             
Sbjct: 1059 HKVIHT-----------GEKLYKCEECGKAYKWPSTLRYHKKIHTGE------------- 1094

Query: 608  NPFCSYSEHQEKNDVFLYRCSVCAKSFRSPSKLERHYLIHAGQKPFECSVCGKTFRQAPH 667
             P+               +C  C K+F + S L +H +IH G+KP++C  CGK F     
Sbjct: 1095 KPY---------------KCEECGKAFSTFSILTKHKVIHTGEKPYKCEECGKAFSWLSV 1139

Query: 668  WKRHQLTH 675
            + +H+  H
Sbjct: 1140 FSKHKKIH 1147



 Score =  147 bits (372), Expect = 2e-35
 Identities = 130/544 (23%), Positives = 228/544 (41%), Gaps = 55/544 (10%)

Query: 156 RKNIHACTICGKMFPSQSKLDRHVLIHTGQRPFKCVLCTKSFRQSTHLKIHQLTHSEERP 215
           R+N + C   GK F   S L  +   HTG++P++C  C K+F + + L  H++ H+ E+ 
Sbjct: 197 RENSYKCEEGGKAFNWSSTLTYYKSAHTGEKPYRCKECGKAFSKFSILTKHKVIHTGEKS 256

Query: 216 FQCCFCQKGFKIQSKLLKHKQIHTRNKAFRALLLKKRRTESRPLP--NKLNANQGGFENG 273
           ++C  C K F   + L KHK IHT  K  +     K  ++   L     ++A +  ++  
Sbjct: 257 YKCEECGKAFNQSAILTKHKIIHTGEKPNKCEECGKAFSKVSTLTTHKAIHAGEKPYKCK 316

Query: 274 EIGES-EENNPLDVHSIYIV---PFQCPKCEKCFESEQILNEHSCFAARSGKIPSRFK-- 327
           E G++  + + L  H        P++C +C K F    IL +H      +G+ P + +  
Sbjct: 317 ECGKAFSKVSTLITHKAIHAGEKPYKCKECGKAFSKFSILTKHK--VIHTGEKPYKCEEC 374

Query: 328 -RSYNYKTIV---KKILAKLKRARSKKLDNFQSEKKVFKKSFLRNCDLISGEQ--SSEQT 381
            ++Y + + +   KKI    K  + ++     S   +  K  +    + +GE+    E+ 
Sbjct: 375 GKAYKWPSTLSYHKKIHTGEKPYKCEECGKGFSMFSILTKHEV----IHTGEKPYKCEEC 430

Query: 382 QRTFVGSLGKHGTYKTIGNRKKKTLTLPFSWQNMGKNLKGILTTENILSIDNSVNKKDLS 441
            + F      + +   + ++K  T   P+  +  GK      T      I          
Sbjct: 431 GKAF------NWSSNLMEHKKIHTGETPYKCEECGKGFSWSSTLSYHKKIHTVEKPYKCE 484

Query: 442 ICGSSGEEFFNNCEVLQCGFSVPRENIRTRHKICPCDKCEKVFPSISKLKRHYLIHTGQR 501
            CG +    FN   +L     +  + I T  K   C++C K F  +S L  H  IH G++
Sbjct: 485 ECGKA----FNQSAIL-----IKHKRIHTGEKPYKCEECGKTFSKVSTLTTHKAIHAGEK 535

Query: 502 PFGCNICGKSFRQSAHLKRHEQTHNEKSPY-ASLCQVEFGNFNNLSNHSGNNVNYNASQQ 560
           P+ C  CGK+F + + L  H+  H  + PY    C   F  F+ L+ H   +       +
Sbjct: 536 PYKCKECGKTFIKVSTLTTHKAIHAGEKPYKCKECGKAFSKFSILTKHKVIHTG-EKPYK 594

Query: 561 CQAPGVQKYEVSESDQMSGVKAESQDFIPGSTGQPCLPNVLLESEQSNPFCSYSEHQEKN 620
           C+       E  ++   S    E +    G     C        E    F ++S   +  
Sbjct: 595 CE-------ECGKAFNWSSNLMEHKRIHTGEKPYKC-------EECGKSFSTFSVLTKHK 640

Query: 621 DVFL----YRCSVCAKSFRSPSKLERHYLIHAGQKPFECSVCGKTFRQAPHWKRHQLTHF 676
            +      Y+C  C K+++  S L  H  IH  +KP++C  CGK F ++    +H+  H 
Sbjct: 641 VIHTGEKPYKCEECGKAYKWSSTLSYHKKIHTVEKPYKCEECGKAFNRSAILIKHKRIHT 700

Query: 677 KERP 680
            E+P
Sbjct: 701 DEKP 704



 Score =  147 bits (370), Expect = 4e-35
 Identities = 130/540 (24%), Positives = 229/540 (42%), Gaps = 74/540 (13%)

Query: 25   RPYVCNICFKHFETPSKLARHYLIHTGQKPFECDVCHKTFRQLVHLERHQLTHSL--PFK 82
            +PY C  C K F T S L +H +IHTG+KP++C+ C K ++    L  H+  H++  P+K
Sbjct: 619  KPYKCEECGKSFSTFSVLTKHKVIHTGEKPYKCEECGKAYKWSSTLSYHKKIHTVEKPYK 678

Query: 83   CSICQRHFKNLKTFVKHQQLHNETYQNNVKQVRRLLEAKQEKSMYGVYNTFTTEERWALH 142
            C  C + F      +KH+++H +      ++  +        + +   +    E+ +   
Sbjct: 679  CEECGKAFNRSAILIKHKRIHTDEKPYKCEECGKTFSKVSTLTTHKAIHA--GEKPYKCK 736

Query: 143  PCSKSDPMYS-MKRRKNIHA------CTICGKMFPSQSKLDRHVLIHTGQRPFKCVLCTK 195
             C K+   +S + + K IH       C  CGK +   S L  H  IHTG++P+KC  C K
Sbjct: 737  ECGKAFSKFSILTKHKVIHTGEKPYKCEECGKAYKWPSTLSYHKKIHTGEKPYKCEECGK 796

Query: 196  SFRQSTHLKIHQLTHSEERPFQCCFCQKGFKIQSKLLKHKQIHTRNKAFRALLLKKRRTE 255
             F   + L  H++ H+ E+P++C  C K F   S   KHK+ H   K ++     K    
Sbjct: 797  GFSMFSILTKHEVIHTGEKPYKCEECGKAFSWLSVFSKHKKTHAGEKFYKCEACGKAYNT 856

Query: 256  SRPLPNK--LNANQGGFENGEIGESEE--NNPLDVHSIYI--VPFQCPKCEKCFESEQIL 309
               L     ++  +  ++  E G++    +N ++   I+    P++C +C+K F     L
Sbjct: 857  FSILTKHKVIHTGEKPYKCEECGKAFNWSSNLMEHKKIHTGETPYKCEECDKAFSWPSSL 916

Query: 310  NEHSCFAARSGKIPSRFKRSYNYKTIVKKILAKLKRARSKKLDNFQSEKKVFKKS--FLR 367
             EH   A  +G+ P + +      +   ++         ++    +   K F  S   + 
Sbjct: 917  TEHK--ATHAGEKPYKCEECGKAFSWPSRLTEHKATHAGEEPYKCEECGKAFNWSSNLME 974

Query: 368  NCDLISGEQ--SSEQTQRTF--VGSLGKHGT----------------YK---TIGNRKK- 403
            +  + +GE+    E+  ++F     L KH                  YK   T+   KK 
Sbjct: 975  HKRIHTGEKPYKCEECGKSFSTFSILTKHKVIHTGEKPYKCEECGKAYKWSSTLSYHKKI 1034

Query: 404  KTLTLPFSWQNMGKN--LKGILTTENILSIDNSVNKKDLSICGSS--------------- 446
             T+  P+  +  GK   +  IL    ++     + K +   CG +               
Sbjct: 1035 HTVEKPYKCEECGKGFVMFSILAKHKVIHTGEKLYKCEE--CGKAYKWPSTLRYHKKIHT 1092

Query: 447  GEEFFNNCEVLQCGFSVPRENIRTRHKIC-------PCDKCEKVFPSISKLKRHYLIHTG 499
            GE+ +  CE  +CG +    +I T+HK+         C++C K F  +S   +H  IHTG
Sbjct: 1093 GEKPYK-CE--ECGKAFSTFSILTKHKVIHTGEKPYKCEECGKAFSWLSVFSKHKKIHTG 1149



 Score =  144 bits (362), Expect = 4e-34
 Identities = 156/647 (24%), Positives = 250/647 (38%), Gaps = 97/647 (14%)

Query: 69  HLERHQLTHSLPFKCSICQRHFKN----------------LKTFVK--HQQLHNETYQNN 110
           +++RH++    P  CS    HF                  L+ + K  H+ LH +    N
Sbjct: 64  NMKRHEMVEESPVICS----HFAQDLWPEQGIEDSFQKVILRRYEKCGHENLHLKIGYTN 119

Query: 111 VKQVRRLLEA--KQEKSMYGVYNTFTTEERWA--LHPCSKSDPMYSMKRRKNIHACTICG 166
           V + +   E   K  +S+    +      ++A   H CS S+        K    C    
Sbjct: 120 VDECKVHKEGYNKLNQSLTTTQSKVFQRGKYANVFHKCSNSNRHKIRHTGKKHLQCKEYV 179

Query: 167 KMFPSQSKLDRHVLIHTGQRPFKCVLCTKSFRQSTHLKIHQLTHSEERPFQCCFCQKGFK 226
           + F   S L +H  I+T +  +KC    K+F  S+ L  ++  H+ E+P++C  C K F 
Sbjct: 180 RSFCMLSHLSQHKRIYTRENSYKCEEGGKAFNWSSTLTYYKSAHTGEKPYRCKECGKAFS 239

Query: 227 IQSKLLKHKQIHTRNKAFRALLLKKRRTESRPLPNKLNANQGGFENGEIGESEENNPLDV 286
             S L KHK IHT  K+++     K   +S  L      + G                  
Sbjct: 240 KFSILTKHKVIHTGEKSYKCEECGKAFNQSAILTKHKIIHTGE----------------- 282

Query: 287 HSIYIVPFQCPKCEKCFESEQILNEHSCFAARSGKIPSRFKR-SYNYKTIVKKILAKLKR 345
                 P +C +C K F     L  H   A  +G+ P + K     +  +   I  K   
Sbjct: 283 -----KPNKCEECGKAFSKVSTLTTHK--AIHAGEKPYKCKECGKAFSKVSTLITHKAIH 335

Query: 346 ARSKKLDNFQSEKKVFKKSFLRNCDLISGEQSSEQTQRTFVGSLGKHGTYK---TIGNRK 402
           A  K     +  K   K S L    +I   +   + +       GK   YK   T+   K
Sbjct: 336 AGEKPYKCKECGKAFSKFSILTKHKVIHTGEKPYKCE-----ECGK--AYKWPSTLSYHK 388

Query: 403 K-KTLTLPFSWQNMGK--NLKGILTTENILSIDNSVNKKDLSICGSSGEEFFNNCEVLQC 459
           K  T   P+  +  GK  ++  ILT   ++       K     C   G+ F  +  +++ 
Sbjct: 389 KIHTGEKPYKCEECGKGFSMFSILTKHEVIHTGEKPYK-----CEECGKAFNWSSNLME- 442

Query: 460 GFSVPRENIRTRHKICPCDKCEKVFPSISKLKRHYLIHTGQRPFGCNICGKSFRQSAHLK 519
                 + I T      C++C K F   S L  H  IHT ++P+ C  CGK+F QSA L 
Sbjct: 443 -----HKKIHTGETPYKCEECGKGFSWSSTLSYHKKIHTVEKPYKCEECGKAFNQSAILI 497

Query: 520 RHEQTHNEKSPY-ASLCQVEFGNFNNLSNHSGNNVNYNASQQCQAPGVQKYEVSESDQMS 578
           +H++ H  + PY    C   F   + L+ H   +       +C+  G    +VS      
Sbjct: 498 KHKRIHTGEKPYKCEECGKTFSKVSTLTTHKAIHAG-EKPYKCKECGKTFIKVSTLTTHK 556

Query: 579 GVKAESQDFIPGSTGQPCLPNVLLESEQSNPFCSYSEHQ-----EKNDVFLYRCSVCAKS 633
            + A  + +     G           +  + F   ++H+     EK     Y+C  C K+
Sbjct: 557 AIHAGEKPYKCKECG-----------KAFSKFSILTKHKVIHTGEKP----YKCEECGKA 601

Query: 634 FRSPSKLERHYLIHAGQKPFECSVCGKTFRQAPHWKRHQLTHFKERP 680
           F   S L  H  IH G+KP++C  CGK+F       +H++ H  E+P
Sbjct: 602 FNWSSNLMEHKRIHTGEKPYKCEECGKSFSTFSVLTKHKVIHTGEKP 648


>gi|194018469 zinc finger protein 546 [Homo sapiens]
          Length = 836

 Score =  214 bits (545), Expect = 2e-55
 Identities = 174/683 (25%), Positives = 294/683 (43%), Gaps = 92/683 (13%)

Query: 23  RNRPYVCNICFKHFETPSKLARHYLIHTGQKPFECDVCHKTFRQLVHLERHQLTHS--LP 80
           R + Y C  C K F   S L +H  IHTG++P++C  C K F ++  L  H   H+   P
Sbjct: 213 REKSYECKECRKAFRQQSYLIQHLRIHTGERPYKCMECGKAFCRVGDLRVHHTIHAGERP 272

Query: 81  FKCSICQRHFKNLKTFVKHQQLHNETYQNNVKQVRRLLEAKQEKSMYGVYNTFTTEER-W 139
           ++C  C + F+      +HQ++H+       K+  +     ++     V+ T    ER +
Sbjct: 273 YECKECGKAFRLHYHLTEHQRIHSGVKPYECKECGKAFSRVRDLR---VHQTIHAGERPY 329

Query: 140 ALHPCSKSDPM-YSMKRRKNIHA------CTICGKMFPSQSKLDRHVLIHTGQRPFKCVL 192
               C K+  + Y +   + IH       C +CGK F  Q  + +H  IHTG +P+KC  
Sbjct: 330 ECKECGKAFRLHYQLTEHQRIHTGERPYECKVCGKTFRVQRHISQHQKIHTGVKPYKCNE 389

Query: 193 CTKSFRQSTHLKIHQLTHSEERPFQCCFCQKGFKIQSKLLKHKQIHTRNKAFRALLLKK- 251
           C K+F   ++L  HQ  H+ E+P++C  C K F   ++L +H++IHT  K +      K 
Sbjct: 390 CGKAFSHGSYLVQHQKIHTGEKPYECKECGKSFSFHAELARHRRIHTGEKPYECRECGKA 449

Query: 252 -RRTESRPLPNKLNANQGGFENGEIGES-----EENNPLDVHSIYIVPFQCPKCEKCFES 305
            R        ++ +  +  +E  E G++     +    L  H+  I P++C +C K F S
Sbjct: 450 FRLQTELTRHHRTHTGEKPYECKECGKAFICGYQLTLHLRTHTGEI-PYECKECGKTFSS 508

Query: 306 EQILNEHSCFAARSGKIPSRFKRSYNYKTIVKKILAKLKRARSKKLDNFQS--EKKVFKK 363
              L +H  +   +G+ P      Y      K    + +  R  ++   +   E K   K
Sbjct: 509 RYHLTQH--YRIHTGEKP------YICNECGKAFRLQGELTRHHRIHTCEKPYECKECGK 560

Query: 364 SFLRNCDLISGEQSSEQTQRTFVGSLGKHGTYKTIGNRKKKTLTLPFSWQNMGKNLKGIL 423
           +F+ +   IS ++             GK      I +R+           N+ ++ K I 
Sbjct: 561 AFIHSNQFISHQRIHTSESTYICKECGK------IFSRR----------YNLTQHFK-IH 603

Query: 424 TTENILSIDNSVNKKDLSICGSSGEEFFNNCEVLQCGFSVPRENIRTRHKICPCDKCEKV 483
           T E               IC   G+ F    E+ Q         I T  K   C +C K 
Sbjct: 604 TGEKPY------------ICNECGKAFRFQTELTQ------HHRIHTGEKPYKCTECGKA 645

Query: 484 FPSISKLKRHYLIHTGQRPFGCNICGKSFRQSAHLKRHEQTHNEKSPY-------ASLCQ 536
           F   + L +H+ IHTG++P+ C  CGK+F +  HL +H + H  + PY       A +C 
Sbjct: 646 FIRSTHLTQHHRIHTGEKPYECTECGKTFSRHYHLTQHHRGHTGEKPYICNECGNAFICS 705

Query: 537 VEFGNFNNLSNHSGNNVNYNASQQCQAPGVQKYEVSESDQM-SGVKAESQDFIPGSTGQP 595
                   +  H+G  + Y   ++C     ++Y +++  ++ +G K  S         + 
Sbjct: 706 YRLTLHQRI--HTG-ELPYEC-KECGKTFSRRYHLTQHFRLHTGEKPYS--------CKE 753

Query: 596 CLPNVLLESEQSNPFCSYSEHQEKNDVFLYRCSVCAKSFRSPSKLERHYLIHAGQKPFEC 655
           C     L++E +     ++  +       Y+C  C K+F   S+L RH+ IH G+KP++C
Sbjct: 754 CGNAFRLQAELTRHHIVHTGEKP------YKCKECGKAFSVNSELTRHHRIHTGEKPYQC 807

Query: 656 SVCGKTFRQAPHWKRHQLTHFKE 678
             CGK F ++     HQ  H  E
Sbjct: 808 KECGKAFIRSDQLTLHQRNHISE 830



 Score =  186 bits (471), Expect = 8e-47
 Identities = 170/655 (25%), Positives = 259/655 (39%), Gaps = 104/655 (15%)

Query: 45  HYLIHTGQKPFECDVCHKTFRQLVHLERHQLTHS--LPFKCSICQRHFKNLKTFVKHQQL 102
           H  IH  +K +EC  C K FRQ  +L +H   H+   P+KC  C + F  +     H  +
Sbjct: 207 HPKIHAREKSYECKECRKAFRQQSYLIQHLRIHTGERPYKCMECGKAFCRVGDLRVHHTI 266

Query: 103 HNETYQNNVKQVRRLLEAKQEKSMYGVYNTFTTEERWALHPCSKSDPMYSMKRRKNIHAC 162
           H            R  E K+    + ++   T  +R  +H   K             + C
Sbjct: 267 HAG---------ERPYECKECGKAFRLHYHLTEHQR--IHSGVKP------------YEC 303

Query: 163 TICGKMFPSQSKLDRHVLIHTGQRPFKCVLCTKSFRQSTHLKIHQLTHSEERPFQCCFCQ 222
             CGK F     L  H  IH G+RP++C  C K+FR    L  HQ  H+ ERP++C  C 
Sbjct: 304 KECGKAFSRVRDLRVHQTIHAGERPYECKECGKAFRLHYQLTEHQRIHTGERPYECKVCG 363

Query: 223 KGFKIQSKLLKHKQIHTRNKAFRALLLKKRRTESRPLPN--KLNANQGGFENGEIGES-- 278
           K F++Q  + +H++IHT  K ++     K  +    L    K++  +  +E  E G+S  
Sbjct: 364 KTFRVQRHISQHQKIHTGVKPYKCNECGKAFSHGSYLVQHQKIHTGEKPYECKECGKSFS 423

Query: 279 ---EENNPLDVHSIYIVPFQCPKCEKCFESEQILNEHSCFAARSGKIPSRFKRSYNYKTI 335
              E      +H+    P++C +C K F  +  L  H      +G+ P      Y  K  
Sbjct: 424 FHAELARHRRIHTGE-KPYECRECGKAFRLQTELTRHH--RTHTGEKP------YECKEC 474

Query: 336 VKKILA--KLKRARSKKLDNFQSEKKVFKKSFLRNCDLISGEQSSEQTQRTFVGSLGKHG 393
            K  +   +L             E K   K+F       S      Q  R   G      
Sbjct: 475 GKAFICGYQLTLHLRTHTGEIPYECKECGKTF-------SSRYHLTQHYRIHTGEK---- 523

Query: 394 TYKTIGNRKKKTLTLPFSWQNMGK--NLKGILTTENILSIDNSVNKKDLSICGSSGEEFF 451
                          P+     GK   L+G LT  + +       +     C   G+ F 
Sbjct: 524 ---------------PYICNECGKAFRLQGELTRHHRIHTCEKPYE-----CKECGKAFI 563

Query: 452 NNCEVLQCGFSVPRENIRTRHKICPCDKCEKVFPSISKLKRHYLIHTGQRPFGCNICGKS 511
           ++ + +        + I T      C +C K+F     L +H+ IHTG++P+ CN CGK+
Sbjct: 564 HSNQFIS------HQRIHTSESTYICKECGKIFSRRYNLTQHFKIHTGEKPYICNECGKA 617

Query: 512 FRQSAHLKRHEQTHNEKSPY-ASLCQVEFGNFNNLSNHSGNNVNYNASQQCQAPGVQKYE 570
           FR    L +H + H  + PY  + C   F    +L+ H   +            G + YE
Sbjct: 618 FRFQTELTQHHRIHTGEKPYKCTECGKAFIRSTHLTQHHRIHT-----------GEKPYE 666

Query: 571 VSESDQMSGVKAESQDFIPGSTGQ-PCLPNVLLESEQSNPF-CSY--SEHQEKNDVFL-Y 625
            +E  +             G TG+ P + N     E  N F CSY  + HQ  +   L Y
Sbjct: 667 CTECGKTFSRHYHLTQHHRGHTGEKPYICN-----ECGNAFICSYRLTLHQRIHTGELPY 721

Query: 626 RCSVCAKSFRSPSKLERHYLIHAGQKPFECSVCGKTFRQAPHWKRHQLTHFKERP 680
            C  C K+F     L +H+ +H G+KP+ C  CG  FR      RH + H  E+P
Sbjct: 722 ECKECGKTFSRRYHLTQHFRLHTGEKPYSCKECGNAFRLQAELTRHHIVHTGEKP 776



 Score =  180 bits (456), Expect = 4e-45
 Identities = 156/621 (25%), Positives = 259/621 (41%), Gaps = 99/621 (15%)

Query: 70  LERHQLTHSLPFKCSICQRHFKNLKTFVKHQQ-LHNETYQNNVKQVRRLLEAKQEKSMYG 128
           LE   +T +L  + ++C+ +   L+T  K +  +H +T   N  Q +   E +QE+   G
Sbjct: 133 LEYKYITKNLLSEKNVCKIYLSQLQTGEKSKNTIHEDTIFRNGLQCKHEFE-RQERHQMG 191

Query: 129 VYNTFTTEERWA--LHPCSKSDPMYSMKRRKNIHACTICGKMFPSQSKLDRHVLIHTGQR 186
             +    +++ +  LHP         +  R+  + C  C K F  QS L +H+ IHTG+R
Sbjct: 192 CVSQMLIQKQISHPLHP--------KIHAREKSYECKECRKAFRQQSYLIQHLRIHTGER 243

Query: 187 PFKCVLCTKSFRQSTHLKIHQLTHSEERPFQCCFCQKGFKIQSKLLKHKQIHTRNKAFRA 246
           P+KC+ C K+F +   L++H   H+ ERP++C  C K F++   L +H++IH+  K +  
Sbjct: 244 PYKCMECGKAFCRVGDLRVHHTIHAGERPYECKECGKAFRLHYHLTEHQRIHSGVKPYEC 303

Query: 247 LLLKKRRTESRPLPNKLNANQGGFENGEIGESEENNPLDVHSIYIVPFQCPKCEKCFESE 306
               K  +  R L      + G                        P++C +C K F   
Sbjct: 304 KECGKAFSRVRDLRVHQTIHAGER----------------------PYECKECGKAFRLH 341

Query: 307 QILNEHSCFAARSGKIPSRFKRSYNYKTIVKKILAKLKRARSKKLDNFQSEKKVFK--KS 364
             L EH      +G+ P      Y  K   K    +   ++ +K+       K  +  K+
Sbjct: 342 YQLTEHQ--RIHTGERP------YECKVCGKTFRVQRHISQHQKIHTGVKPYKCNECGKA 393

Query: 365 FLRNCDLISGEQSSEQTQRTFVGSLGKHGTY--KTIGNRKKKTLTLPFSWQNMGKNLKGI 422
           F     L+  ++     +       GK  ++  +   +R+  T   P+  +  GK  +  
Sbjct: 394 FSHGSYLVQHQKIHTGEKPYECKECGKSFSFHAELARHRRIHTGEKPYECRECGKAFR-- 451

Query: 423 LTTENILSIDNSVNKKDLSICGSSGEEFFNNCEVLQCGFSVPRENIRTRHKICP--CDKC 480
           L TE          +K    C   G+ F        CG+ +   ++RT     P  C +C
Sbjct: 452 LQTELTRHHRTHTGEKPYE-CKECGKAFI-------CGYQLTL-HLRTHTGEIPYECKEC 502

Query: 481 EKVFPSISKLKRHYLIHTGQRPFGCNICGKSFRQSAHLKRHEQTHNEKSPY-ASLCQVEF 539
            K F S   L +HY IHTG++P+ CN CGK+FR    L RH + H  + PY    C   F
Sbjct: 503 GKTFSSRYHLTQHYRIHTGEKPYICNECGKAFRLQGELTRHHRIHTCEKPYECKECGKAF 562

Query: 540 GNFNNLSNHSGNNVNYNASQQCQAPGVQKYEVSESDQMSGVKAESQDFIPGSTGQPCLPN 599
            + N   +H                  Q+   SES  +                  C   
Sbjct: 563 IHSNQFISH------------------QRIHTSESTYI------------------CKEC 586

Query: 600 VLLESEQSNPFCSYSEHQEKNDVFLYRCSVCAKSFRSPSKLERHYLIHAGQKPFECSVCG 659
             + S + N    +  H  +     Y C+ C K+FR  ++L +H+ IH G+KP++C+ CG
Sbjct: 587 GKIFSRRYNLTQHFKIHTGEKP---YICNECGKAFRFQTELTQHHRIHTGEKPYKCTECG 643

Query: 660 KTFRQAPHWKRHQLTHFKERP 680
           K F ++ H  +H   H  E+P
Sbjct: 644 KAFIRSTHLTQHHRIHTGEKP 664


>gi|157167158 zinc finger protein 808 [Homo sapiens]
          Length = 903

 Score =  214 bits (544), Expect = 3e-55
 Identities = 172/677 (25%), Positives = 272/677 (40%), Gaps = 136/677 (20%)

Query: 25  RPYVCNICFKHFETPSKLARHYLIHTGQKPFECDVCHKTFRQLVHLERHQLTHS--LPFK 82
           +PY CN C K F   S L  H  IHTG+KP++C+ C K F Q  HL RHQ  H+   P+K
Sbjct: 313 KPYKCNECGKVFRQNSALVIHKAIHTGEKPYKCNECGKAFNQQSHLSRHQRLHTGVKPYK 372

Query: 83  CSICQRHFKNLKTFVKHQQLHNETYQNNVKQVRRLLEAKQEKSMYGVYNTFTTEERWALH 142
           C IC+      K F  H  L N T                                  +H
Sbjct: 373 CKICE------KAFACHSYLANHT---------------------------------RIH 393

Query: 143 PCSKSDPMYSMKRRKNIHACTICGKMFPSQSKLDRHVLIHTGQRPFKCVLCTKSFRQSTH 202
              K+            + C  CGK F  QS L RH ++HTG++P+KC  C K F Q + 
Sbjct: 394 SGEKT------------YKCNECGKAFNHQSSLARHHILHTGEKPYKCEECDKVFSQKST 441

Query: 203 LKIHQLTHSEERPFQCCFCQKGFKIQSKLLKHKQIHTRNKAFRALLLKK--RRTESRPLP 260
           L+ H+  H+ E+P++C  C   F   S+L +H++IHT  K ++    +K   R  S    
Sbjct: 442 LERHKRIHTGEKPYKCKVCDTAFTCNSQLARHRRIHTGEKTYKCNECRKTFSRRSSLLCH 501

Query: 261 NKLNANQGGFENGEIGESEENNPLDVHSIYI----VPFQCPKCEKCFESEQILNEHSCFA 316
            +L++ +  ++  + G +  +    V+   +      ++C  C K F    +L  H+   
Sbjct: 502 RRLHSGEKPYKCNQCGNTFRHRASLVYHRRLHTLEKSYKCTVCNKVFMRNSVLAVHTRIH 561

Query: 317 ARSGKIPSRFKRSYNYKTIVKKILAKLKRARSKKLDNFQSEKKVFKKSFLRNCDLISGEQ 376
                     K+ Y      K    +   +R ++L   +   K         CD + G++
Sbjct: 562 TA--------KKPYKCNECGKAFNQQSHLSRHRRLHTGEKPYK------CEACDKVFGQK 607

Query: 377 SSEQTQRTFVGSLGKHGTYKTIGNRKKKTLTLPFSWQNMGKNLKGILTTENILSIDNSVN 436
           S+ ++ +        H   K     + +     F+W +       I T E     +    
Sbjct: 608 SALESHKRI------HTGEKPY---RCQVCDTAFTWNSQLARHTRIHTGEKTYKCNEC-- 656

Query: 437 KKDLSICGS-------SGEEFFNNCEVLQCGF-----SVPRENIRTRHKICPCDKCEKVF 484
            K  S   S        G E    C+V    F           I +  K   C++C K F
Sbjct: 657 GKTFSYKSSLVWHRRLHGGEKSYKCKVCDKAFVCRSYVAKHTRIHSGMKPYKCNECSKTF 716

Query: 485 PSISKLKRHYLIHTGQRPFGCNICGKSFRQSAHLKRHEQTHNEKSPY-ASLCQVEFGNFN 543
            + S L  H  IH+G++P+ C+ C K+F Q A L  H + H+ + PY  + C   F +++
Sbjct: 717 SNRSSLVCHRRIHSGEKPYKCSECSKTFSQKATLLCHRRLHSGEKPYKCNDCGNTFRHWS 776

Query: 544 NLSNHSGNNVNYNASQQCQAPGVQKYEVSESDQMSGVKAESQDFIPGSTGQPCLPNVLLE 603
           +L  H   +            G + Y+ +  D+          F+  S     L   +  
Sbjct: 777 SLVYHRRLHT-----------GEKSYKCTVCDKA---------FVRNS----YLARHIRI 812

Query: 604 SEQSNPFCSYSEHQEKNDVFLYRCSVCAKSFRSPSKLERHYLIHAGQKPFECSVCGKTFR 663
                P               Y+C+ C K+F   S L RH+ IH G+KP++C  C K F 
Sbjct: 813 HTAEKP---------------YKCNECGKAFNEQSHLSRHHRIHTGEKPYKCEACDKVFS 857

Query: 664 QAPHWKRHQLTHFKERP 680
           +  H KRH++ H  E+P
Sbjct: 858 RKSHLKRHRIIHTGEKP 874



 Score =  188 bits (477), Expect = 2e-47
 Identities = 134/538 (24%), Positives = 224/538 (41%), Gaps = 55/538 (10%)

Query: 25  RPYVCNICFKHFETPSKLARHYLIHTGQKPFECDVCHKTFRQLVHLERHQLTHS--LPFK 82
           + Y CN C K F   S LARH+++HTG+KP++C+ C K F Q   LERH+  H+   P+K
Sbjct: 397 KTYKCNECGKAFNHQSSLARHHILHTGEKPYKCEECDKVFSQKSTLERHKRIHTGEKPYK 456

Query: 83  CSICQRHFKNLKTFVKHQQLHNETYQNNVKQVRRLLEAKQEKSMYGVYNTFTTEERWALH 142
           C +C   F       +H+++H         + R+    +   S+       + E+ +  +
Sbjct: 457 CKVCDTAFTCNSQLARHRRIHTGEKTYKCNECRKTFSRRS--SLLCHRRLHSGEKPYKCN 514

Query: 143 PCSKS-DPMYSMKRRKNIHA------CTICGKMFPSQSKLDRHVLIHTGQRPFKCVLCTK 195
            C  +     S+   + +H       CT+C K+F   S L  H  IHT ++P+KC  C K
Sbjct: 515 QCGNTFRHRASLVYHRRLHTLEKSYKCTVCNKVFMRNSVLAVHTRIHTAKKPYKCNECGK 574

Query: 196 SFRQSTHLKIHQLTHSEERPFQCCFCQKGFKIQSKLLKHKQIHTRNKAFRALLLKKRRTE 255
           +F Q +HL  H+  H+ E+P++C  C K F  +S L  HK+IHT  K +R  +     T 
Sbjct: 575 AFNQQSHLSRHRRLHTGEKPYKCEACDKVFGQKSALESHKRIHTGEKPYRCQVCDTAFTW 634

Query: 256 SRPLPNKLNANQGGFENGEIGESEENNPLDVHSIYIVPFQCPKCEKCFESEQILNEHSCF 315
           +  L      + G                         ++C +C K F  +  L  H   
Sbjct: 635 NSQLARHTRIHTGE----------------------KTYKCNECGKTFSYKSSLVWHRRL 672

Query: 316 AARSGKIPSRFKRSYNYKTIVKKILAKLKRARSKKLDNFQSEKKVFK--KSFLRNCDLIS 373
                      ++SY  K   K  + +   A+  ++ +     K  +  K+F     L+ 
Sbjct: 673 HGG--------EKSYKCKVCDKAFVCRSYVAKHTRIHSGMKPYKCNECSKTFSNRSSLVC 724

Query: 374 GEQSSEQTQRTFVGSLGKHGTYKT--IGNRKKKTLTLPFSWQNMGKNLKGILTTENILSI 431
             +     +        K  + K   + +R+  +   P+   + G   +   +      +
Sbjct: 725 HRRIHSGEKPYKCSECSKTFSQKATLLCHRRLHSGEKPYKCNDCGNTFRHWSSLVYHRRL 784

Query: 432 DNSVNKKDLSICGSSGEEFFNNCEVLQCGFSVPRENIRTRHKICPCDKCEKVFPSISKLK 491
                    ++C  +   F  N       +      I T  K   C++C K F   S L 
Sbjct: 785 HTGEKSYKCTVCDKA---FVRN------SYLARHIRIHTAEKPYKCNECGKAFNEQSHLS 835

Query: 492 RHYLIHTGQRPFGCNICGKSFRQSAHLKRHEQTHNEKSPY-ASLCQVEFGNFNNLSNH 548
           RH+ IHTG++P+ C  C K F + +HLKRH   H  + PY  + C   F + + L +H
Sbjct: 836 RHHRIHTGEKPYKCEACDKVFSRKSHLKRHRIIHTGEKPYKCNECGKAFSDRSTLIHH 893



 Score =  182 bits (462), Expect = 9e-46
 Identities = 160/652 (24%), Positives = 262/652 (40%), Gaps = 90/652 (13%)

Query: 40  SKLARHYLIHTGQKPFECDVCHKTFRQLVHLERHQLTH--SLPFKCSICQRHFKNLKTFV 97
           S L +   +H  +K F C+   K F     L +HQ+ H     +KC +C + F + +   
Sbjct: 216 SLLPQKQEVHMREKSFPCNESGKAFNCSSLLRKHQIPHLGDKQYKCDVCGKLFNHKQYLA 275

Query: 98  KHQQLHNETYQNNVKQVRRLLEAKQEKSMYGVYNTFTTEERWALHPCSKSDPMYSMKRRK 157
            H++ H        K+  +    K         ++ T   R  LH   K           
Sbjct: 276 CHRRCHTGEKPYKCKECGKSFSYK---------SSLTCHHR--LHTGVKP---------- 314

Query: 158 NIHACTICGKMFPSQSKLDRHVLIHTGQRPFKCVLCTKSFRQSTHLKIHQLTHSEERPFQ 217
             + C  CGK+F   S L  H  IHTG++P+KC  C K+F Q +HL  HQ  H+  +P++
Sbjct: 315 --YKCNECGKVFRQNSALVIHKAIHTGEKPYKCNECGKAFNQQSHLSRHQRLHTGVKPYK 372

Query: 218 CCFCQKGFKIQSKLLKHKQIHTRNKAFRALLLKKRRTESRPLPNKLNANQGGFENGEIGE 277
           C  C+K F   S L  H +IH+  K ++     K       L     A       GE   
Sbjct: 373 CKICEKAFACHSYLANHTRIHSGEKTYKCNECGKAFNHQSSL-----ARHHILHTGE--- 424

Query: 278 SEENNPLDVHSIYIVPFQCPKCEKCFESEQILNEHSCFAARSGKIPSRFKRSYNYKTIVK 337
                          P++C +C+K F  +  L  H      +G+ P + K      T   
Sbjct: 425 --------------KPYKCEECDKVFSQKSTLERHK--RIHTGEKPYKCKVCDTAFTCNS 468

Query: 338 KILAKLKRARSKKLDNFQSEKKVFKK--SFLRNCDLISGEQSSEQTQRTFVGSLGKHGTY 395
           ++    +    +K       +K F +  S L +  L SGE+  +  Q    G+  +H   
Sbjct: 469 QLARHRRIHTGEKTYKCNECRKTFSRRSSLLCHRRLHSGEKPYKCNQ---CGNTFRHRA- 524

Query: 396 KTIGNRKKKTLTLPFSWQNMGKNLKGILTTENILSIDNSVNK-KDLSICGSSGEEFFNNC 454
             + +R+  TL   +      K    +    ++L++   ++  K    C   G+ F    
Sbjct: 525 SLVYHRRLHTLEKSYKCTVCNK----VFMRNSVLAVHTRIHTAKKPYKCNECGKAFNQQS 580

Query: 455 EVLQCGFSVPRENIRTRHKICPCDKCEKVFPSISKLKRHYLIHTGQRPFGCNICGKSFRQ 514
            + +         + T  K   C+ C+KVF   S L+ H  IHTG++P+ C +C  +F  
Sbjct: 581 HLSR------HRRLHTGEKPYKCEACDKVFGQKSALESHKRIHTGEKPYRCQVCDTAFTW 634

Query: 515 SAHLKRHEQTH-NEKSPYASLCQVEFGNFNNLSNH---SGNNVNYNASQQCQAPGVQKYE 570
           ++ L RH + H  EK+   + C   F   ++L  H    G   +Y      +A   + Y 
Sbjct: 635 NSQLARHTRIHTGEKTYKCNECGKTFSYKSSLVWHRRLHGGEKSYKCKVCDKAFVCRSYV 694

Query: 571 VSESDQMSGVKAESQDFIPGSTGQPCLPNVLLESEQSNPFCSYSEHQEKNDVFLYRCSVC 630
              +   SG+K              C       S +S+  C    H  +     Y+CS C
Sbjct: 695 AKHTRIHSGMKP-----------YKCNECSKTFSNRSSLVCHRRIHSGEKP---YKCSEC 740

Query: 631 AKSFRSPSKLERHYLIHAGQKPFECSVCGKTFRQAPHWKR---HQLTHFKER 679
           +K+F   + L  H  +H+G+KP++C+ CG TFR   HW     H+  H  E+
Sbjct: 741 SKTFSQKATLLCHRRLHSGEKPYKCNDCGNTFR---HWSSLVYHRRLHTGEK 789



 Score =  145 bits (365), Expect = 2e-34
 Identities = 90/331 (27%), Positives = 154/331 (46%), Gaps = 31/331 (9%)

Query: 11  KIQQCVVANKL--------------PRNRPYVCNICFKHFETPSKLARHYLIHTGQKPFE 56
           K  +C V NK+                 +PY CN C K F   S L+RH  +HTG+KP++
Sbjct: 537 KSYKCTVCNKVFMRNSVLAVHTRIHTAKKPYKCNECGKAFNQQSHLSRHRRLHTGEKPYK 596

Query: 57  CDVCHKTFRQLVHLERHQLTHS--LPFKCSICQRHFKNLKTFVKHQQLHNETYQNNVKQV 114
           C+ C K F Q   LE H+  H+   P++C +C   F       +H ++H         + 
Sbjct: 597 CEACDKVFGQKSALESHKRIHTGEKPYRCQVCDTAFTWNSQLARHTRIHTGEKTYKCNEC 656

Query: 115 RRLLEAKQEKSMYGVYNTFTTEERWALHPCSKSDPMYS-MKRRKNIHA------CTICGK 167
            +    K   S+         E+ +    C K+    S + +   IH+      C  C K
Sbjct: 657 GKTFSYKS--SLVWHRRLHGGEKSYKCKVCDKAFVCRSYVAKHTRIHSGMKPYKCNECSK 714

Query: 168 MFPSQSKLDRHVLIHTGQRPFKCVLCTKSFRQSTHLKIHQLTHSEERPFQCCFCQKGFKI 227
            F ++S L  H  IH+G++P+KC  C+K+F Q   L  H+  HS E+P++C  C   F+ 
Sbjct: 715 TFSNRSSLVCHRRIHSGEKPYKCSECSKTFSQKATLLCHRRLHSGEKPYKCNDCGNTFRH 774

Query: 228 QSKLLKHKQIHTRNKAFRALLLKKRRTESRPLPN--KLNANQGGFENGEIGE--SEENNP 283
            S L+ H+++HT  K+++  +  K    +  L    +++  +  ++  E G+  +E+++ 
Sbjct: 775 WSSLVYHRRLHTGEKSYKCTVCDKAFVRNSYLARHIRIHTAEKPYKCNECGKAFNEQSHL 834

Query: 284 LDVHSIYI--VPFQCPKCEKCFESEQILNEH 312
              H I+    P++C  C+K F  +  L  H
Sbjct: 835 SRHHRIHTGEKPYKCEACDKVFSRKSHLKRH 865



 Score =  131 bits (329), Expect = 2e-30
 Identities = 135/559 (24%), Positives = 226/559 (40%), Gaps = 57/559 (10%)

Query: 156 RKNIHACTICGKMFPSQSKLDRHVLIHTGQRPFKCVLCTKSFRQSTHLKIHQLTHSEERP 215
           R  IH     G    + S L +   +H  ++ F C    K+F  S+ L+ HQ+ H  ++ 
Sbjct: 199 RPQIHISNNYGNNPLNSSLLPQKQEVHMREKSFPCNESGKAFNCSSLLRKHQIPHLGDKQ 258

Query: 216 FQCCFCQKGFKIQSKLLKHKQIHTRNKAFRALLLKKRRTESRPLP--NKLNANQGGFENG 273
           ++C  C K F  +  L  H++ HT  K ++     K  +    L   ++L+     ++  
Sbjct: 259 YKCDVCGKLFNHKQYLACHRRCHTGEKPYKCKECGKSFSYKSSLTCHHRLHTGVKPYKCN 318

Query: 274 EIGE-SEENNPLDVHSIYIV---PFQCPKCEKCFESEQILNEHSCFAARSGKIPSRFKRS 329
           E G+   +N+ L +H        P++C +C K F  +  L+ H      +G  P      
Sbjct: 319 ECGKVFRQNSALVIHKAIHTGEKPYKCNECGKAFNQQSHLSRHQ--RLHTGVKP------ 370

Query: 330 YNYKTIVKKILAKLKRARSKKLDNFQSEKKV--------FKKSFLRNCDLISGEQ--SSE 379
           Y  K   K        A   ++ + +   K          + S  R+  L +GE+    E
Sbjct: 371 YKCKICEKAFACHSYLANHTRIHSGEKTYKCNECGKAFNHQSSLARHHILHTGEKPYKCE 430

Query: 380 QTQRTF--VGSLGKHGTYKTIGNR--KKKTLTLPFSWQNMGKNLKGILTTENILSID--- 432
           +  + F    +L +H    T G +  K K     F+  +     + I T E     +   
Sbjct: 431 ECDKVFSQKSTLERHKRIHT-GEKPYKCKVCDTAFTCNSQLARHRRIHTGEKTYKCNECR 489

Query: 433 NSVNKKDLSICG---SSGEEFFNNCEVLQCGFS-------VPRENIRTRHKICPCDKCEK 482
            + +++   +C     SGE+ +  C   QCG +       V    + T  K   C  C K
Sbjct: 490 KTFSRRSSLLCHRRLHSGEKPY-KCN--QCGNTFRHRASLVYHRRLHTLEKSYKCTVCNK 546

Query: 483 VFPSISKLKRHYLIHTGQRPFGCNICGKSFRQSAHLKRHEQTHNEKSPY-ASLCQVEFGN 541
           VF   S L  H  IHT ++P+ CN CGK+F Q +HL RH + H  + PY    C   FG 
Sbjct: 547 VFMRNSVLAVHTRIHTAKKPYKCNECGKAFNQQSHLSRHRRLHTGEKPYKCEACDKVFGQ 606

Query: 542 FNNLSNHSGNNVNYNASQQCQAPGVQKYEVSESDQMSGVKAESQDFIPGSTGQPCLPNVL 601
            + L +H   +       +CQ         S+  + + +    + +     G+       
Sbjct: 607 KSALESHKRIHTG-EKPYRCQVCDTAFTWNSQLARHTRIHTGEKTYKCNECGK------T 659

Query: 602 LESEQSNPFCSYSEHQEKNDVFLYRCSVCAKSFRSPSKLERHYLIHAGQKPFECSVCGKT 661
              + S  +       EK+    Y+C VC K+F   S + +H  IH+G KP++C+ C KT
Sbjct: 660 FSYKSSLVWHRRLHGGEKS----YKCKVCDKAFVCRSYVAKHTRIHSGMKPYKCNECSKT 715

Query: 662 FRQAPHWKRHQLTHFKERP 680
           F        H+  H  E+P
Sbjct: 716 FSNRSSLVCHRRIHSGEKP 734



 Score = 99.8 bits (247), Expect = 8e-21
 Identities = 67/231 (29%), Positives = 105/231 (45%), Gaps = 27/231 (11%)

Query: 468 IRTRHKICPCDKCEKVFPSISKLKRHYLIHTGQRPFGCNICGKSFRQSAHLKRHEQTHNE 527
           I +  K   C++C K F   S L RH+++HTG++P+ C  C K F Q + L+RH++ H  
Sbjct: 392 IHSGEKTYKCNECGKAFNHQSSLARHHILHTGEKPYKCEECDKVFSQKSTLERHKRIHTG 451

Query: 528 KSPY-ASLCQVEFGNFNNLSNHSGNNVNYNASQQCQAPGVQKYEVSESDQMSGVKAE--- 583
           + PY   +C   F   + L+ H   +            G + Y+ +E  +    ++    
Sbjct: 452 EKPYKCKVCDTAFTCNSQLARHRRIHT-----------GEKTYKCNECRKTFSRRSSLLC 500

Query: 584 SQDFIPGSTGQPCLPNVLLESEQSNPF---CSYSEHQEKNDVFL-YRCSVCAKSFRSPSK 639
            +    G     C       ++  N F    S   H+  + +   Y+C+VC K F   S 
Sbjct: 501 HRRLHSGEKPYKC-------NQCGNTFRHRASLVYHRRLHTLEKSYKCTVCNKVFMRNSV 553

Query: 640 LERHYLIHAGQKPFECSVCGKTFRQAPHWKRHQLTHFKERPQGKVVALDSV 690
           L  H  IH  +KP++C+ CGK F Q  H  RH+  H  E+P  K  A D V
Sbjct: 554 LAVHTRIHTAKKPYKCNECGKAFNQQSHLSRHRRLHTGEKPY-KCEACDKV 603



 Score = 96.7 bits (239), Expect = 7e-20
 Identities = 84/357 (23%), Positives = 147/357 (41%), Gaps = 39/357 (10%)

Query: 343 LKRARSKKLDNF---QSEKKVFKKSFLRNCDLISGEQSSEQTQRTFVGSLGKHGTYKTIG 399
           L+R +S  + +F   + EK++    F    D  +G ++     +   GS  +H  ++  G
Sbjct: 90  LQRHQSYHIGDFCFQEIEKEIHNIEFQCQEDERNGHEAPTTKIKKLTGSTDQHD-HRHAG 148

Query: 400 NRKKKTLTLPFSWQNMGK----NLKGILTT--ENILSIDNSVNKKDLSICGSS---GEEF 450
           N+  K       + ++ +     +KG +    E   S  +SV+      C         +
Sbjct: 149 NKPIKDQLGSSFYSHLPELHIFQIKGEIANQLEKSTSDASSVSTSQRISCRPQIHISNNY 208

Query: 451 FNNCEVLQCGFSVPRENIRTRHKICPCDKCEKVFPSISKLKRHYLIHTGQRPFGCNICGK 510
            NN   L       ++ +  R K  PC++  K F   S L++H + H G + + C++CGK
Sbjct: 209 GNN--PLNSSLLPQKQEVHMREKSFPCNESGKAFNCSSLLRKHQIPHLGDKQYKCDVCGK 266

Query: 511 SFRQSAHLKRHEQTHNEKSPYASLCQVEFGNFNNLSNHSGNNVNYNASQQCQA---PGVQ 567
            F    +L  H + H  + PY                  G + +Y +S  C      GV+
Sbjct: 267 LFNHKQYLACHRRCHTGEKPYKC-------------KECGKSFSYKSSLTCHHRLHTGVK 313

Query: 568 KYEVSESDQM---SGVKAESQDFIPGSTGQPCLPNVLLESEQSNPFCSYSEHQEKND-VF 623
            Y+ +E  ++   +      +    G     C       ++QS+     S HQ  +  V 
Sbjct: 314 PYKCNECGKVFRQNSALVIHKAIHTGEKPYKCNECGKAFNQQSH----LSRHQRLHTGVK 369

Query: 624 LYRCSVCAKSFRSPSKLERHYLIHAGQKPFECSVCGKTFRQAPHWKRHQLTHFKERP 680
            Y+C +C K+F   S L  H  IH+G+K ++C+ CGK F       RH + H  E+P
Sbjct: 370 PYKCKICEKAFACHSYLANHTRIHSGEKTYKCNECGKAFNHQSSLARHHILHTGEKP 426



 Score = 56.6 bits (135), Expect = 7e-08
 Identities = 24/55 (43%), Positives = 31/55 (56%)

Query: 25  RPYVCNICFKHFETPSKLARHYLIHTGQKPFECDVCHKTFRQLVHLERHQLTHSL 79
           +PY C  C K F   S L RH +IHTG+KP++C+ C K F     L  HQ  H +
Sbjct: 845 KPYKCEACDKVFSRKSHLKRHRIIHTGEKPYKCNECGKAFSDRSTLIHHQAIHGI 899


>gi|40217792 zinc finger protein 585A [Homo sapiens]
          Length = 714

 Score =  209 bits (532), Expect = 7e-54
 Identities = 178/670 (26%), Positives = 285/670 (42%), Gaps = 88/670 (13%)

Query: 22  PRNRPYVCNICFKHFETPSKLARHYLIHTGQKPFECDVCHKTFRQLVHLERHQLTH--SL 79
           P  + Y C    K F   S+L  H  +  G+K + C  C K F Q      HQ TH    
Sbjct: 70  PGEKAYECAKFEKIFTQKSQLKVHLKVLAGEKLYVCIECGKAFVQKPEFIIHQKTHMREK 129

Query: 80  PFKCSICQRHFKNLKTFVKHQQLHNETYQNNVKQVRRLLEAKQEKSMYGVYNTFTTEERW 139
           PFKC+ C + F  + +  +HQ++H            +L E  Q    +   +  +  E+ 
Sbjct: 130 PFKCNECGKSFFQVSSLFRHQRIHTG---------EKLYECSQCGKGFSYNSDLSIHEK- 179

Query: 140 ALHPCSKSDPMYSMKRRKNIHACTICGKMFPSQSKLDRHVLIHTGQRPFKCVLCTKSFRQ 199
                     +++ +R    H CT CGK F  +S L  H  IHTG+R + C+ C ++F Q
Sbjct: 180 ----------IHTGERH---HECTDCGKAFTQKSTLKMHQKIHTGERSYICIECGQAFIQ 226

Query: 200 STHLKIHQLTHSEERPFQCCFCQKGFKIQSKLLKHKQIHTRNKAFRALLLKKRRTESRPL 259
            THL  H+  H+ E+P++C  C K F  +S+L  H+++HTR K +         TE    
Sbjct: 227 KTHLIAHRRIHTGEKPYECSNCGKSFISKSQLQVHQRVHTRVKPYIC-------TEY--- 276

Query: 260 PNKLNANQGGFENGEIGESEENNPLDVHSIYIVPFQCPKCEKCF--ESEQILNEHSCFAA 317
             K+ +N       +  +S E + +           C +C K F   SE I+++      
Sbjct: 277 -GKVFSNNSNLVTHKKVQSREKSSI-----------CTECGKAFTYRSELIIHQR----I 320

Query: 318 RSGKIPSRFKRSYNYKTIVKKILAKLKRARSKKLDNFQSEKKVFK--KSFLRNCDLISGE 375
            +G+ P      Y      K    K      +++   +      K   +F++   LI+ +
Sbjct: 321 HTGEKP------YECSDCGKAFTQKSALTVHQRIHTGEKSYICMKCGLAFIQKAHLIAHQ 374

Query: 376 QSSEQTQRTFVGSLGKHGTYKTIGNRKKKTLT--LPFSWQNMGKNLKGILTTENILSIDN 433
                 +    G  GK  T K+  +  K+  T   P+     GK         N+++   
Sbjct: 375 IIHTGEKPHKCGHCGKLFTSKSQLHVHKRIHTGEKPYMCNKCGK---AFTNRSNLITHQK 431

Query: 434 SVNKKDLSICGSSGEEFFNNCEVLQCGFSVPRENIRTRHKICPCDKCEKVFPSISKLKRH 493
           +   +   IC   G+ F    ++      +  + I T  K   C+ C K F   S L  H
Sbjct: 432 THTGEKSYICSKCGKAFTQRSDL------ITHQRIHTGEKPYECNTCGKAFTQKSHLNIH 485

Query: 494 YLIHTGQRPFGCNICGKSFRQSAHLKRHEQTHNEKSPYASL-CQVEFGNFNNLSNHSGNN 552
             IHTG+R + C+ CGK+F Q + L  H++ H  + PY    C   F   +N   H   +
Sbjct: 486 QKIHTGERQYECHECGKAFNQKSILIVHQKIHTGEKPYVCTECGRAFIRKSNFITHQRIH 545

Query: 553 VNYNASQQCQAPGVQKYEVSESDQMSGVKAESQDFIPGSTGQPCLPNVLLESEQS-NPFC 611
                       G + YE S+  +    K++     P  TG+   P V  E  ++ +   
Sbjct: 546 T-----------GEKPYECSDCGKSFTSKSQLLVHQPVHTGEK--PYVCAECGKAFSGRS 592

Query: 612 SYSEHQEKNDVFL-YRCSVCAKSFRSPSKLERHYLIHAGQKPFECSVCGKTFRQAPHWKR 670
           + S+HQ+ +     Y CS C K+FR  S+L  H+ IH G+KP+ECS CGK+F +    + 
Sbjct: 593 NLSKHQKTHTGEKPYICSECGKTFRQKSELITHHRIHTGEKPYECSDCGKSFTKKSQLQV 652

Query: 671 HQLTHFKERP 680
           HQ  H  E+P
Sbjct: 653 HQRIHTGEKP 662



 Score =  164 bits (415), Expect = 3e-40
 Identities = 147/603 (24%), Positives = 244/603 (40%), Gaps = 89/603 (14%)

Query: 23  RNRPYVCNICFKHFETPSKLARHYLIHTGQKPFECDVCHKTFRQLVHLERHQLTHS--LP 80
           R +P+ CN C K F   S L RH  IHTG+K +EC  C K F     L  H+  H+    
Sbjct: 127 REKPFKCNECGKSFFQVSSLFRHQRIHTGEKLYECSQCGKGFSYNSDLSIHEKIHTGERH 186

Query: 81  FKCSICQRHFKNLKTFVKHQQLHN--------ETYQNNVKQV-----RRLLEAKQEKSMY 127
            +C+ C + F    T   HQ++H         E  Q  +++      RR+   ++     
Sbjct: 187 HECTDCGKAFTQKSTLKMHQKIHTGERSYICIECGQAFIQKTHLIAHRRIHTGEKPYECS 246

Query: 128 GVYNTFTTEERWALHP----------CSKSDPMYS----------MKRRKNIHACTICGK 167
               +F ++ +  +H           C++   ++S          ++ R+    CT CGK
Sbjct: 247 NCGKSFISKSQLQVHQRVHTRVKPYICTEYGKVFSNNSNLVTHKKVQSREKSSICTECGK 306

Query: 168 MFPSQSKLDRHVLIHTGQRPFKCVLCTKSFRQST-------------------------- 201
            F  +S+L  H  IHTG++P++C  C K+F Q +                          
Sbjct: 307 AFTYRSELIIHQRIHTGEKPYECSDCGKAFTQKSALTVHQRIHTGEKSYICMKCGLAFIQ 366

Query: 202 --HLKIHQLTHSEERPFQCCFCQKGFKIQSKLLKHKQIHTRNKAFRALLLKKRRTESRPL 259
             HL  HQ+ H+ E+P +C  C K F  +S+L  HK+IHT  K +      K  T    L
Sbjct: 367 KAHLIAHQIIHTGEKPHKCGHCGKLFTSKSQLHVHKRIHTGEKPYMCNKCGKAFTNRSNL 426

Query: 260 --PNKLNANQGGFENGEIGES-EENNPLDVHSIYIV---PFQCPKCEKCFESEQILNEHS 313
               K +  +  +   + G++  + + L  H        P++C  C K F  +  LN H 
Sbjct: 427 ITHQKTHTGEKSYICSKCGKAFTQRSDLITHQRIHTGEKPYECNTCGKAFTQKSHLNIHQ 486

Query: 314 CFAARSGKIP-SRFKRSYNYKTIVKKILAKLKRARSKKLDNFQSEKKVFKKSFLRNCDLI 372
                  +       +++N K+I+  +  K+       +        + K +F+ +  + 
Sbjct: 487 KIHTGERQYECHECGKAFNQKSIL-IVHQKIHTGEKPYVCTECGRAFIRKSNFITHQRIH 545

Query: 373 SGEQSSEQTQRTFVGSLGKHGTYKT--IGNRKKKTLTLPFSWQNMGKNLKGILTTENILS 430
           +GE+  E          GK  T K+  + ++   T   P+     GK   G     N+  
Sbjct: 546 TGEKPYE------CSDCGKSFTSKSQLLVHQPVHTGEKPYVCAECGKAFSG---RSNLSK 596

Query: 431 IDNSVNKKDLSICGSSGEEFFNNCEVLQCGFSVPRENIRTRHKICPCDKCEKVFPSISKL 490
              +   +   IC   G+ F    E+      +    I T  K   C  C K F   S+L
Sbjct: 597 HQKTHTGEKPYICSECGKTFRQKSEL------ITHHRIHTGEKPYECSDCGKSFTKKSQL 650

Query: 491 KRHYLIHTGQRPFGCNICGKSFRQSAHLKRHEQTHNEKSPY-ASLCQVEFGNFNNLSNHS 549
           + H  IHTG++P+ C  CGK+F   ++L +H+ TH    PY   +C   F   +  S H 
Sbjct: 651 QVHQRIHTGEKPYVCAECGKAFTDRSNLNKHQTTHTGDKPYKCGICGKGFVQKSVFSVHQ 710

Query: 550 GNN 552
            ++
Sbjct: 711 SSH 713



 Score =  139 bits (351), Expect = 7e-33
 Identities = 135/572 (23%), Positives = 231/572 (40%), Gaps = 73/572 (12%)

Query: 165 CGKMFPSQSKLDRHVLIHTGQRPFKCVLCTKSFRQSTHLKIHQLTHSEERPFQCCFCQKG 224
           C K+   +    +   ++ G++ ++C    K F Q + LK+H    + E+ + C  C K 
Sbjct: 52  CRKILSYKQVSSQPQKMYPGEKAYECAKFEKIFTQKSQLKVHLKVLAGEKLYVCIECGKA 111

Query: 225 FKIQSKLLKHKQIHTRNKAFRALLLKKR--RTESRPLPNKLNANQGGFENGEIGES-EEN 281
           F  + + + H++ H R K F+     K   +  S     +++  +  +E  + G+    N
Sbjct: 112 FVQKPEFIIHQKTHMREKPFKCNECGKSFFQVSSLFRHQRIHTGEKLYECSQCGKGFSYN 171

Query: 282 NPLDVHSIYIV---PFQCPKCEKCFESEQILNEH----------------SCFAARSGKI 322
           + L +H          +C  C K F  +  L  H                  F  ++  I
Sbjct: 172 SDLSIHEKIHTGERHHECTDCGKAFTQKSTLKMHQKIHTGERSYICIECGQAFIQKTHLI 231

Query: 323 PSR----FKRSYNYKTIVKKILAKL-----KRARSKKLDNFQSEKKVFKKSFLRNCDLIS 373
             R     ++ Y      K  ++K      +R  ++      +E   + K F  N +L++
Sbjct: 232 AHRRIHTGEKPYECSNCGKSFISKSQLQVHQRVHTRVKPYICTE---YGKVFSNNSNLVT 288

Query: 374 GEQSSEQTQRTFVGSLGKHGTYKT--IGNRKKKTLTLPFSWQNMGKNLKGILTTENILSI 431
            ++   + + +     GK  TY++  I +++  T   P+   + GK      T ++ L++
Sbjct: 289 HKKVQSREKSSICTECGKAFTYRSELIIHQRIHTGEKPYECSDCGK----AFTQKSALTV 344

Query: 432 DNSVNKKDLS-ICGSSGEEFFNNCEVLQCGFSVPRENIRTRHKICPCDKCEKVFPSISKL 490
              ++  + S IC   G  F      +Q    +  + I T  K   C  C K+F S S+L
Sbjct: 345 HQRIHTGEKSYICMKCGLAF------IQKAHLIAHQIIHTGEKPHKCGHCGKLFTSKSQL 398

Query: 491 KRHYLIHTGQRPFGCNICGKSFRQSAHLKRHEQTH-NEKSPYASLCQVEFGNFNNLSNHS 549
             H  IHTG++P+ CN CGK+F   ++L  H++TH  EKS   S C   F   ++L  H 
Sbjct: 399 HVHKRIHTGEKPYMCNKCGKAFTNRSNLITHQKTHTGEKSYICSKCGKAFTQRSDLITHQ 458

Query: 550 ------------------GNNVNYNASQQCQAPGVQKYEVSESDQMSGVKA---ESQDFI 588
                                 + N  Q+    G ++YE  E  +    K+     Q   
Sbjct: 459 RIHTGEKPYECNTCGKAFTQKSHLNIHQKIHT-GERQYECHECGKAFNQKSILIVHQKIH 517

Query: 589 PGSTGQPCLPNVLLESEQSNPFCSYSEHQEKNDVFLYRCSVCAKSFRSPSKLERHYLIHA 648
            G     C         +SN       H  +     Y CS C KSF S S+L  H  +H 
Sbjct: 518 TGEKPYVCTECGRAFIRKSNFITHQRIHTGEKP---YECSDCGKSFTSKSQLLVHQPVHT 574

Query: 649 GQKPFECSVCGKTFRQAPHWKRHQLTHFKERP 680
           G+KP+ C+ CGK F    +  +HQ TH  E+P
Sbjct: 575 GEKPYVCAECGKAFSGRSNLSKHQKTHTGEKP 606



 Score =  110 bits (275), Expect = 4e-24
 Identities = 61/199 (30%), Positives = 91/199 (45%), Gaps = 17/199 (8%)

Query: 25  RPYVCNICFKHFETPSKLARHYLIHTGQKPFECDVCHKTFRQLVHLERHQLTHS--LPFK 82
           +PYVC  C + F   S    H  IHTG+KP+EC  C K+F     L  HQ  H+   P+ 
Sbjct: 521 KPYVCTECGRAFIRKSNFITHQRIHTGEKPYECSDCGKSFTSKSQLLVHQPVHTGEKPYV 580

Query: 83  CSICQRHFKNLKTFVKHQQLHNETYQNNVKQVRRLLEAKQEKSMYGVYNTFTTEERWALH 142
           C+ C + F       KHQ+ H         +  +    K E   +  +   T E+ +   
Sbjct: 581 CAECGKAFSGRSNLSKHQKTHTGEKPYICSECGKTFRQKSELITH--HRIHTGEKPYECS 638

Query: 143 PCSKSDPMYSMKRRKNIH----------ACTICGKMFPSQSKLDRHVLIHTGQRPFKCVL 192
            C KS   ++ K +  +H           C  CGK F  +S L++H   HTG +P+KC +
Sbjct: 639 DCGKS---FTKKSQLQVHQRIHTGEKPYVCAECGKAFTDRSNLNKHQTTHTGDKPYKCGI 695

Query: 193 CTKSFRQSTHLKIHQLTHS 211
           C K F Q +   +HQ +H+
Sbjct: 696 CGKGFVQKSVFSVHQSSHA 714



 Score = 51.2 bits (121), Expect = 3e-06
 Identities = 29/92 (31%), Positives = 41/92 (44%), Gaps = 5/92 (5%)

Query: 594 QPCLPNVLLESEQSNPFCSYSEHQEKNDVFL-----YRCSVCAKSFRSPSKLERHYLIHA 648
           Q C    L +  Q     SY +   +          Y C+   K F   S+L+ H  + A
Sbjct: 39  QSCPGEKLWDHNQCRKILSYKQVSSQPQKMYPGEKAYECAKFEKIFTQKSQLKVHLKVLA 98

Query: 649 GQKPFECSVCGKTFRQAPHWKRHQLTHFKERP 680
           G+K + C  CGK F Q P +  HQ TH +E+P
Sbjct: 99  GEKLYVCIECGKAFVQKPEFIIHQKTHMREKP 130


>gi|22749331 zinc finger protein 585A [Homo sapiens]
          Length = 714

 Score =  209 bits (532), Expect = 7e-54
 Identities = 178/670 (26%), Positives = 285/670 (42%), Gaps = 88/670 (13%)

Query: 22  PRNRPYVCNICFKHFETPSKLARHYLIHTGQKPFECDVCHKTFRQLVHLERHQLTH--SL 79
           P  + Y C    K F   S+L  H  +  G+K + C  C K F Q      HQ TH    
Sbjct: 70  PGEKAYECAKFEKIFTQKSQLKVHLKVLAGEKLYVCIECGKAFVQKPEFIIHQKTHMREK 129

Query: 80  PFKCSICQRHFKNLKTFVKHQQLHNETYQNNVKQVRRLLEAKQEKSMYGVYNTFTTEERW 139
           PFKC+ C + F  + +  +HQ++H            +L E  Q    +   +  +  E+ 
Sbjct: 130 PFKCNECGKSFFQVSSLFRHQRIHTG---------EKLYECSQCGKGFSYNSDLSIHEK- 179

Query: 140 ALHPCSKSDPMYSMKRRKNIHACTICGKMFPSQSKLDRHVLIHTGQRPFKCVLCTKSFRQ 199
                     +++ +R    H CT CGK F  +S L  H  IHTG+R + C+ C ++F Q
Sbjct: 180 ----------IHTGERH---HECTDCGKAFTQKSTLKMHQKIHTGERSYICIECGQAFIQ 226

Query: 200 STHLKIHQLTHSEERPFQCCFCQKGFKIQSKLLKHKQIHTRNKAFRALLLKKRRTESRPL 259
            THL  H+  H+ E+P++C  C K F  +S+L  H+++HTR K +         TE    
Sbjct: 227 KTHLIAHRRIHTGEKPYECSNCGKSFISKSQLQVHQRVHTRVKPYIC-------TEY--- 276

Query: 260 PNKLNANQGGFENGEIGESEENNPLDVHSIYIVPFQCPKCEKCF--ESEQILNEHSCFAA 317
             K+ +N       +  +S E + +           C +C K F   SE I+++      
Sbjct: 277 -GKVFSNNSNLVTHKKVQSREKSSI-----------CTECGKAFTYRSELIIHQR----I 320

Query: 318 RSGKIPSRFKRSYNYKTIVKKILAKLKRARSKKLDNFQSEKKVFK--KSFLRNCDLISGE 375
            +G+ P      Y      K    K      +++   +      K   +F++   LI+ +
Sbjct: 321 HTGEKP------YECSDCGKAFTQKSALTVHQRIHTGEKSYICMKCGLAFIQKAHLIAHQ 374

Query: 376 QSSEQTQRTFVGSLGKHGTYKTIGNRKKKTLT--LPFSWQNMGKNLKGILTTENILSIDN 433
                 +    G  GK  T K+  +  K+  T   P+     GK         N+++   
Sbjct: 375 IIHTGEKPHKCGHCGKLFTSKSQLHVHKRIHTGEKPYMCNKCGK---AFTNRSNLITHQK 431

Query: 434 SVNKKDLSICGSSGEEFFNNCEVLQCGFSVPRENIRTRHKICPCDKCEKVFPSISKLKRH 493
           +   +   IC   G+ F    ++      +  + I T  K   C+ C K F   S L  H
Sbjct: 432 THTGEKSYICSKCGKAFTQRSDL------ITHQRIHTGEKPYECNTCGKAFTQKSHLNIH 485

Query: 494 YLIHTGQRPFGCNICGKSFRQSAHLKRHEQTHNEKSPYASL-CQVEFGNFNNLSNHSGNN 552
             IHTG+R + C+ CGK+F Q + L  H++ H  + PY    C   F   +N   H   +
Sbjct: 486 QKIHTGERQYECHECGKAFNQKSILIVHQKIHTGEKPYVCTECGRAFIRKSNFITHQRIH 545

Query: 553 VNYNASQQCQAPGVQKYEVSESDQMSGVKAESQDFIPGSTGQPCLPNVLLESEQS-NPFC 611
                       G + YE S+  +    K++     P  TG+   P V  E  ++ +   
Sbjct: 546 T-----------GEKPYECSDCGKSFTSKSQLLVHQPVHTGEK--PYVCAECGKAFSGRS 592

Query: 612 SYSEHQEKNDVFL-YRCSVCAKSFRSPSKLERHYLIHAGQKPFECSVCGKTFRQAPHWKR 670
           + S+HQ+ +     Y CS C K+FR  S+L  H+ IH G+KP+ECS CGK+F +    + 
Sbjct: 593 NLSKHQKTHTGEKPYICSECGKTFRQKSELITHHRIHTGEKPYECSDCGKSFTKKSQLQV 652

Query: 671 HQLTHFKERP 680
           HQ  H  E+P
Sbjct: 653 HQRIHTGEKP 662



 Score =  164 bits (415), Expect = 3e-40
 Identities = 147/603 (24%), Positives = 244/603 (40%), Gaps = 89/603 (14%)

Query: 23  RNRPYVCNICFKHFETPSKLARHYLIHTGQKPFECDVCHKTFRQLVHLERHQLTHS--LP 80
           R +P+ CN C K F   S L RH  IHTG+K +EC  C K F     L  H+  H+    
Sbjct: 127 REKPFKCNECGKSFFQVSSLFRHQRIHTGEKLYECSQCGKGFSYNSDLSIHEKIHTGERH 186

Query: 81  FKCSICQRHFKNLKTFVKHQQLHN--------ETYQNNVKQV-----RRLLEAKQEKSMY 127
            +C+ C + F    T   HQ++H         E  Q  +++      RR+   ++     
Sbjct: 187 HECTDCGKAFTQKSTLKMHQKIHTGERSYICIECGQAFIQKTHLIAHRRIHTGEKPYECS 246

Query: 128 GVYNTFTTEERWALHP----------CSKSDPMYS----------MKRRKNIHACTICGK 167
               +F ++ +  +H           C++   ++S          ++ R+    CT CGK
Sbjct: 247 NCGKSFISKSQLQVHQRVHTRVKPYICTEYGKVFSNNSNLVTHKKVQSREKSSICTECGK 306

Query: 168 MFPSQSKLDRHVLIHTGQRPFKCVLCTKSFRQST-------------------------- 201
            F  +S+L  H  IHTG++P++C  C K+F Q +                          
Sbjct: 307 AFTYRSELIIHQRIHTGEKPYECSDCGKAFTQKSALTVHQRIHTGEKSYICMKCGLAFIQ 366

Query: 202 --HLKIHQLTHSEERPFQCCFCQKGFKIQSKLLKHKQIHTRNKAFRALLLKKRRTESRPL 259
             HL  HQ+ H+ E+P +C  C K F  +S+L  HK+IHT  K +      K  T    L
Sbjct: 367 KAHLIAHQIIHTGEKPHKCGHCGKLFTSKSQLHVHKRIHTGEKPYMCNKCGKAFTNRSNL 426

Query: 260 --PNKLNANQGGFENGEIGES-EENNPLDVHSIYIV---PFQCPKCEKCFESEQILNEHS 313
               K +  +  +   + G++  + + L  H        P++C  C K F  +  LN H 
Sbjct: 427 ITHQKTHTGEKSYICSKCGKAFTQRSDLITHQRIHTGEKPYECNTCGKAFTQKSHLNIHQ 486

Query: 314 CFAARSGKIP-SRFKRSYNYKTIVKKILAKLKRARSKKLDNFQSEKKVFKKSFLRNCDLI 372
                  +       +++N K+I+  +  K+       +        + K +F+ +  + 
Sbjct: 487 KIHTGERQYECHECGKAFNQKSIL-IVHQKIHTGEKPYVCTECGRAFIRKSNFITHQRIH 545

Query: 373 SGEQSSEQTQRTFVGSLGKHGTYKT--IGNRKKKTLTLPFSWQNMGKNLKGILTTENILS 430
           +GE+  E          GK  T K+  + ++   T   P+     GK   G     N+  
Sbjct: 546 TGEKPYE------CSDCGKSFTSKSQLLVHQPVHTGEKPYVCAECGKAFSG---RSNLSK 596

Query: 431 IDNSVNKKDLSICGSSGEEFFNNCEVLQCGFSVPRENIRTRHKICPCDKCEKVFPSISKL 490
              +   +   IC   G+ F    E+      +    I T  K   C  C K F   S+L
Sbjct: 597 HQKTHTGEKPYICSECGKTFRQKSEL------ITHHRIHTGEKPYECSDCGKSFTKKSQL 650

Query: 491 KRHYLIHTGQRPFGCNICGKSFRQSAHLKRHEQTHNEKSPY-ASLCQVEFGNFNNLSNHS 549
           + H  IHTG++P+ C  CGK+F   ++L +H+ TH    PY   +C   F   +  S H 
Sbjct: 651 QVHQRIHTGEKPYVCAECGKAFTDRSNLNKHQTTHTGDKPYKCGICGKGFVQKSVFSVHQ 710

Query: 550 GNN 552
            ++
Sbjct: 711 SSH 713



 Score =  139 bits (351), Expect = 7e-33
 Identities = 135/572 (23%), Positives = 231/572 (40%), Gaps = 73/572 (12%)

Query: 165 CGKMFPSQSKLDRHVLIHTGQRPFKCVLCTKSFRQSTHLKIHQLTHSEERPFQCCFCQKG 224
           C K+   +    +   ++ G++ ++C    K F Q + LK+H    + E+ + C  C K 
Sbjct: 52  CRKILSYKQVSSQPQKMYPGEKAYECAKFEKIFTQKSQLKVHLKVLAGEKLYVCIECGKA 111

Query: 225 FKIQSKLLKHKQIHTRNKAFRALLLKKR--RTESRPLPNKLNANQGGFENGEIGES-EEN 281
           F  + + + H++ H R K F+     K   +  S     +++  +  +E  + G+    N
Sbjct: 112 FVQKPEFIIHQKTHMREKPFKCNECGKSFFQVSSLFRHQRIHTGEKLYECSQCGKGFSYN 171

Query: 282 NPLDVHSIYIV---PFQCPKCEKCFESEQILNEH----------------SCFAARSGKI 322
           + L +H          +C  C K F  +  L  H                  F  ++  I
Sbjct: 172 SDLSIHEKIHTGERHHECTDCGKAFTQKSTLKMHQKIHTGERSYICIECGQAFIQKTHLI 231

Query: 323 PSR----FKRSYNYKTIVKKILAKL-----KRARSKKLDNFQSEKKVFKKSFLRNCDLIS 373
             R     ++ Y      K  ++K      +R  ++      +E   + K F  N +L++
Sbjct: 232 AHRRIHTGEKPYECSNCGKSFISKSQLQVHQRVHTRVKPYICTE---YGKVFSNNSNLVT 288

Query: 374 GEQSSEQTQRTFVGSLGKHGTYKT--IGNRKKKTLTLPFSWQNMGKNLKGILTTENILSI 431
            ++   + + +     GK  TY++  I +++  T   P+   + GK      T ++ L++
Sbjct: 289 HKKVQSREKSSICTECGKAFTYRSELIIHQRIHTGEKPYECSDCGK----AFTQKSALTV 344

Query: 432 DNSVNKKDLS-ICGSSGEEFFNNCEVLQCGFSVPRENIRTRHKICPCDKCEKVFPSISKL 490
              ++  + S IC   G  F      +Q    +  + I T  K   C  C K+F S S+L
Sbjct: 345 HQRIHTGEKSYICMKCGLAF------IQKAHLIAHQIIHTGEKPHKCGHCGKLFTSKSQL 398

Query: 491 KRHYLIHTGQRPFGCNICGKSFRQSAHLKRHEQTH-NEKSPYASLCQVEFGNFNNLSNHS 549
             H  IHTG++P+ CN CGK+F   ++L  H++TH  EKS   S C   F   ++L  H 
Sbjct: 399 HVHKRIHTGEKPYMCNKCGKAFTNRSNLITHQKTHTGEKSYICSKCGKAFTQRSDLITHQ 458

Query: 550 ------------------GNNVNYNASQQCQAPGVQKYEVSESDQMSGVKA---ESQDFI 588
                                 + N  Q+    G ++YE  E  +    K+     Q   
Sbjct: 459 RIHTGEKPYECNTCGKAFTQKSHLNIHQKIHT-GERQYECHECGKAFNQKSILIVHQKIH 517

Query: 589 PGSTGQPCLPNVLLESEQSNPFCSYSEHQEKNDVFLYRCSVCAKSFRSPSKLERHYLIHA 648
            G     C         +SN       H  +     Y CS C KSF S S+L  H  +H 
Sbjct: 518 TGEKPYVCTECGRAFIRKSNFITHQRIHTGEKP---YECSDCGKSFTSKSQLLVHQPVHT 574

Query: 649 GQKPFECSVCGKTFRQAPHWKRHQLTHFKERP 680
           G+KP+ C+ CGK F    +  +HQ TH  E+P
Sbjct: 575 GEKPYVCAECGKAFSGRSNLSKHQKTHTGEKP 606



 Score =  110 bits (275), Expect = 4e-24
 Identities = 61/199 (30%), Positives = 91/199 (45%), Gaps = 17/199 (8%)

Query: 25  RPYVCNICFKHFETPSKLARHYLIHTGQKPFECDVCHKTFRQLVHLERHQLTHS--LPFK 82
           +PYVC  C + F   S    H  IHTG+KP+EC  C K+F     L  HQ  H+   P+ 
Sbjct: 521 KPYVCTECGRAFIRKSNFITHQRIHTGEKPYECSDCGKSFTSKSQLLVHQPVHTGEKPYV 580

Query: 83  CSICQRHFKNLKTFVKHQQLHNETYQNNVKQVRRLLEAKQEKSMYGVYNTFTTEERWALH 142
           C+ C + F       KHQ+ H         +  +    K E   +  +   T E+ +   
Sbjct: 581 CAECGKAFSGRSNLSKHQKTHTGEKPYICSECGKTFRQKSELITH--HRIHTGEKPYECS 638

Query: 143 PCSKSDPMYSMKRRKNIH----------ACTICGKMFPSQSKLDRHVLIHTGQRPFKCVL 192
            C KS   ++ K +  +H           C  CGK F  +S L++H   HTG +P+KC +
Sbjct: 639 DCGKS---FTKKSQLQVHQRIHTGEKPYVCAECGKAFTDRSNLNKHQTTHTGDKPYKCGI 695

Query: 193 CTKSFRQSTHLKIHQLTHS 211
           C K F Q +   +HQ +H+
Sbjct: 696 CGKGFVQKSVFSVHQSSHA 714



 Score = 51.2 bits (121), Expect = 3e-06
 Identities = 29/92 (31%), Positives = 41/92 (44%), Gaps = 5/92 (5%)

Query: 594 QPCLPNVLLESEQSNPFCSYSEHQEKNDVFL-----YRCSVCAKSFRSPSKLERHYLIHA 648
           Q C    L +  Q     SY +   +          Y C+   K F   S+L+ H  + A
Sbjct: 39  QSCPGEKLWDHNQCRKILSYKQVSSQPQKMYPGEKAYECAKFEKIFTQKSQLKVHLKVLA 98

Query: 649 GQKPFECSVCGKTFRQAPHWKRHQLTHFKERP 680
           G+K + C  CGK F Q P +  HQ TH +E+P
Sbjct: 99  GEKLYVCIECGKAFVQKPEFIIHQKTHMREKP 130


>gi|49574543 zinc finger protein 616 [Homo sapiens]
          Length = 781

 Score =  209 bits (531), Expect = 9e-54
 Identities = 175/693 (25%), Positives = 296/693 (42%), Gaps = 125/693 (18%)

Query: 15  CVVANKLPRNRPYVCNICFKHFETPSKLARHYLIHTGQKPFECDVCHKTFRQLVHLERHQ 74
           C+V+  + R + YVCN C K F+  S L  H  IHT +KP++C+ C K F +   L  H+
Sbjct: 174 CLVSPHI-REKTYVCNECGKAFKASSSLINHQRIHTTEKPYKCNECGKAFHRASLLTVHK 232

Query: 75  LTHS--LPFKCSICQRHFKNLKTFVKHQQLHNETYQNNVKQVRRLLEAKQEKSMYGVYNT 132
           + H+    ++C +C + F+    FV+HQ+ H                             
Sbjct: 233 VVHTRGKSYQCDVCGKIFRKNSYFVRHQRSH----------------------------- 263

Query: 133 FTTEERWALHPCSKSDPMYS-MKRRKNIHA------CTICGKMFPSQSKLDRHVLIHTGQ 185
            T ++ +  + C KS    S +   + IH       C +CGK F  +  L  H  +HTG+
Sbjct: 264 -TGQKPYICNECGKSFSKSSHLAVHQRIHTGEKPYKCNLCGKSFSQRVHLRLHQTVHTGE 322

Query: 186 RPFKCVLCTKSFRQSTHLKIHQLTHSEERPFQCCFCQKGFKIQSKLLKHKQIHTRNKAF- 244
           RPFKC  C K+F++S++L +HQ+ H+ ++P++C  C K F+ +S L+ H++IH+  K + 
Sbjct: 323 RPFKCNECGKTFKRSSNLTVHQVIHAGKKPYKCDVCGKAFRHRSNLVCHRRIHSGEKQYK 382

Query: 245 ----------RALLLKKRRTESRPLPNKLNANQGGFENGEIGESEENNPLDVHSIYIVPF 294
                     R+ L   RR  +   P K N      E G++    + + L VH       
Sbjct: 383 CNECGKVFSKRSSLAVHRRIHTVEKPCKCN------ECGKV--FSKRSSLAVHQRIHTGQ 434

Query: 295 QCPKCEKCFESEQILNEHSCFAARSGKIPSRFKRSYNYKTIVKKILAKLKRARSKKLDNF 354
           +  KC KC    ++ ++HS  A    +I +  +++Y      K      + A  +++   
Sbjct: 435 KTYKCNKC---GKVYSKHSHLAVH-WRIHTG-EKAYKCNECGKVFSIHSRLAAHQRIHTG 489

Query: 355 QSEKKVFK--KSFLRNCDLISGEQSSEQTQRTFVGSLGKHGTYKTIGNRKKKTLT--LPF 410
           +   K  +  K F ++  L    +     +       GK  + ++   R ++  T   P+
Sbjct: 490 EKPYKCNECGKVFSQHSRLAVHRRIHTGEKPYKCKECGKVFSDRSAFARHRRIHTGEKPY 549

Query: 411 SWQNMGKNLKGILTTENILSIDNSVNKKDLSICGSSGEEFF--NNCEVLQCGFS--VPRE 466
             +  GK    + +  + L++   ++         SGE+ +  N C  +   +S  V   
Sbjct: 550 KCKECGK----VFSQCSRLTVHRRIH---------SGEKPYKCNECGKVYSQYSHLVGHR 596

Query: 467 NIRTRHKICPCDKCEKVFPSISKLKRHYLIHTGQRPFGCNICGKSFRQSAHLKRHEQTHN 526
            + T  K   C +C K F   S L RH  IHTG++P+ CN CG SF Q  HL+ H+  H 
Sbjct: 597 RVHTGEKPYKCHECGKAFNQGSTLNRHQRIHTGEKPYKCNQCGNSFSQRVHLRLHQTVHT 656

Query: 527 EKSPY-ASLCQVEFGNFNNLSNHSGNNVNYNASQQCQAPGVQKYEVSESDQMSGVKAESQ 585
              PY  + C   F   +NL+ H           Q    G + Y+  E  ++    +   
Sbjct: 657 GDRPYKCNECGKTFKRSSNLTAH-----------QIIHAGKKPYKCDECGKVFRHSSHLV 705

Query: 586 DFIPGSTGQPCLPNVLLESEQSNPFCSYSEHQEKNDVFLYRCSVCAKSFRSPSKLERHYL 645
                 TG+                              Y+C  C K+F     L +H  
Sbjct: 706 SHQRIHTGEK----------------------------RYKCIECGKAFGRLFSLSKHQR 737

Query: 646 IHAGQKPFECSVCGKTFRQAPHWKRHQLTHFKE 678
           IH+G+KP++C+ CGK+F       +H++ H  E
Sbjct: 738 IHSGKKPYKCNECGKSFICRSGLTKHRIRHTGE 770



 Score =  184 bits (466), Expect = 3e-46
 Identities = 147/532 (27%), Positives = 234/532 (43%), Gaps = 54/532 (10%)

Query: 25  RPYVCNICFKHFETPSKLARHYLIHTGQKPFECDVCHKTFRQLVHLERHQLTHS--LPFK 82
           +PY+CN C K F   S LA H  IHTG+KP++C++C K+F Q VHL  HQ  H+   PFK
Sbjct: 267 KPYICNECGKSFSKSSHLAVHQRIHTGEKPYKCNLCGKSFSQRVHLRLHQTVHTGERPFK 326

Query: 83  CSICQRHFKNLKTFVKHQQLH--NETYQNNV--KQVRRLLEAKQEKSMYGVYNTFTTEER 138
           C+ C + FK       HQ +H   + Y+ +V  K  R        + ++      + E++
Sbjct: 327 CNECGKTFKRSSNLTVHQVIHAGKKPYKCDVCGKAFRHRSNLVCHRRIH------SGEKQ 380

Query: 139 WALHPCSKS-DPMYSMKRRKNIHA------CTICGKMFPSQSKLDRHVLIHTGQRPFKCV 191
           +  + C K      S+   + IH       C  CGK+F  +S L  H  IHTGQ+ +KC 
Sbjct: 381 YKCNECGKVFSKRSSLAVHRRIHTVEKPCKCNECGKVFSKRSSLAVHQRIHTGQKTYKCN 440

Query: 192 LCTKSFRQSTHLKIHQLTHSEERPFQCCFCQKGFKIQSKLLKHKQIHTRNKAFRALLLKK 251
            C K + + +HL +H   H+ E+ ++C  C K F I S+L  H++IHT  K ++     K
Sbjct: 441 KCGKVYSKHSHLAVHWRIHTGEKAYKCNECGKVFSIHSRLAAHQRIHTGEKPYKCNECGK 500

Query: 252 RRTESRPLP--NKLNANQGGFENGEIGESEENNPLDVHSIYI----VPFQCPKCEKCFES 305
             ++   L    +++  +  ++  E G+   +         I     P++C +C K F  
Sbjct: 501 VFSQHSRLAVHRRIHTGEKPYKCKECGKVFSDRSAFARHRRIHTGEKPYKCKECGKVFSQ 560

Query: 306 EQILNEHSCFAARSGKIPSRFKRSYNYKTIVKKILAKLKRARSKKLDNFQSEKKVFKK-- 363
              L  H      SG+ P +        +    ++   +    +K        K F +  
Sbjct: 561 CSRLTVHR--RIHSGEKPYKCNECGKVYSQYSHLVGHRRVHTGEKPYKCHECGKAFNQGS 618

Query: 364 SFLRNCDLISGEQ--SSEQTQRTFVGS--LGKHGTYKTIGNRKKKTLTLPFSWQNMGKNL 419
           +  R+  + +GE+     Q   +F     L  H T  T G+R       P+     GK  
Sbjct: 619 TLNRHQRIHTGEKPYKCNQCGNSFSQRVHLRLHQTVHT-GDR-------PYKCNECGKTF 670

Query: 420 K--GILTTENILSIDNSVNKKDLSICGSSGEEFFNNCEVLQCGFSVPRENIRTRHKICPC 477
           K    LT   I+       K     C   G+ F ++  +      V  + I T  K   C
Sbjct: 671 KRSSNLTAHQIIHAGKKPYK-----CDECGKVFRHSSHL------VSHQRIHTGEKRYKC 719

Query: 478 DKCEKVFPSISKLKRHYLIHTGQRPFGCNICGKSFRQSAHLKRHEQTHNEKS 529
            +C K F  +  L +H  IH+G++P+ CN CGKSF   + L +H   H  +S
Sbjct: 720 IECGKAFGRLFSLSKHQRIHSGKKPYKCNECGKSFICRSGLTKHRIRHTGES 771



 Score =  174 bits (442), Expect = 2e-43
 Identities = 159/664 (23%), Positives = 254/664 (38%), Gaps = 118/664 (17%)

Query: 40  SKLARHYLIHTGQKPFECDVCHKTFRQLVHLERHQLTHSLPFKCSICQRHFKNLKTFVKH 99
           S+LA    + T  + +EC+   KT      +  H       + C+ C + FK   + + H
Sbjct: 146 SRLAELQKVQTEGRLYECNETEKTGNNGCLVSPH--IREKTYVCNECGKAFKASSSLINH 203

Query: 100 QQLHNETYQNNVKQVRRLLEAKQEKSMYGVYNTFTTEERWALHPCSKSDPMYSM------ 153
           Q++H                              TTE+ +  + C K+    S+      
Sbjct: 204 QRIH------------------------------TTEKPYKCNECGKAFHRASLLTVHKV 233

Query: 154 -KRRKNIHACTICGKMFPSQSKLDRHVLIHTGQRPFKCVLCTKSFRQSTHLKIHQLTHSE 212
              R   + C +CGK+F   S   RH   HTGQ+P+ C  C KSF +S+HL +HQ  H+ 
Sbjct: 234 VHTRGKSYQCDVCGKIFRKNSYFVRHQRSHTGQKPYICNECGKSFSKSSHLAVHQRIHTG 293

Query: 213 ERPFQCCFCQKGFKIQSKLLKHKQIHTRNKAFRALLLKKRRTESRPLPNKLNANQGGFEN 272
           E+P++C  C K F  +  L  H+ +HT  + F+                           
Sbjct: 294 EKPYKCNLCGKSFSQRVHLRLHQTVHTGERPFKC-------------------------- 327

Query: 273 GEIGES-EENNPLDVHSIYIV---PFQCPKCEKCFESEQILNEHSCFAARSGKIPSRFKR 328
            E G++ + ++ L VH +      P++C  C K F     L  H      SG+      +
Sbjct: 328 NECGKTFKRSSNLTVHQVIHAGKKPYKCDVCGKAFRHRSNLVCHR--RIHSGE------K 379

Query: 329 SYNYKTIVKKILAKLKRARSKKLDNFQSEKKVFKKSFLRNCDLISGEQSSEQT-QRTFVG 387
            Y      K    +   A  +++   +   K         C  +  ++SS    QR   G
Sbjct: 380 QYKCNECGKVFSKRSSLAVHRRIHTVEKPCKC------NECGKVFSKRSSLAVHQRIHTG 433

Query: 388 SLGKHGTYKT--IGNRKKKTLTLPFSWQ-NMGKNLKGILTTENILSIDNSV--------N 436
                 TYK    G    K   L   W+ + G+          + SI + +         
Sbjct: 434 QK----TYKCNKCGKVYSKHSHLAVHWRIHTGEKAYKCNECGKVFSIHSRLAAHQRIHTG 489

Query: 437 KKDLSICGSSGEEFFNNCEVLQCGFSVPRENIRTRHKICPCDKCEKVFPSISKLKRHYLI 496
           +K    C   G+ F  +  +           I T  K   C +C KVF   S   RH  I
Sbjct: 490 EKPYK-CNECGKVFSQHSRL------AVHRRIHTGEKPYKCKECGKVFSDRSAFARHRRI 542

Query: 497 HTGQRPFGCNICGKSFRQSAHLKRHEQTHNEKSPY-ASLCQVEFGNFNNLSNHSGNNVNY 555
           HTG++P+ C  CGK F Q + L  H + H+ + PY  + C   +  +++L  H   +   
Sbjct: 543 HTGEKPYKCKECGKVFSQCSRLTVHRRIHSGEKPYKCNECGKVYSQYSHLVGHRRVHTG- 601

Query: 556 NASQQCQAPGVQKYEVSESDQMSGVKAESQDFIPGSTGQPCLPNVLLESEQSNPFCSYSE 615
               +C   G    + S  ++   +    + +     G      V L   Q+        
Sbjct: 602 EKPYKCHECGKAFNQGSTLNRHQRIHTGEKPYKCNQCGNSFSQRVHLRLHQT-------V 654

Query: 616 HQEKNDVFLYRCSVCAKSFRSPSKLERHYLIHAGQKPFECSVCGKTFRQAPHWKRHQLTH 675
           H        Y+C+ C K+F+  S L  H +IHAG+KP++C  CGK FR + H   HQ  H
Sbjct: 655 HTGDRP---YKCNECGKTFKRSSNLTAHQIIHAGKKPYKCDECGKVFRHSSHLVSHQRIH 711

Query: 676 FKER 679
             E+
Sbjct: 712 TGEK 715



 Score =  154 bits (388), Expect = 3e-37
 Identities = 142/594 (23%), Positives = 236/594 (39%), Gaps = 102/594 (17%)

Query: 97  VKHQQLHNETYQNNVKQVRRLLEAKQEKSMYGVYNTFTTEERWALHPCSKSDPMYSMKRR 156
           V++  + N+   N   ++  L + + E  +Y    T  T     L          S   R
Sbjct: 131 VENNHIENQLTSNFESRLAELQKVQTEGRLYECNETEKTGNNGCL---------VSPHIR 181

Query: 157 KNIHACTICGKMFPSQSKLDRHVLIHTGQRPFKCVLCTKSFRQSTHLKIHQLTHSEERPF 216
           +  + C  CGK F + S L  H  IHT ++P+KC  C K+F +++ L +H++ H+  + +
Sbjct: 182 EKTYVCNECGKAFKASSSLINHQRIHTTEKPYKCNECGKAFHRASLLTVHKVVHTRGKSY 241

Query: 217 QCCFCQKGFKIQSKLLKHKQIHTRNKAFRALLLKKRRTESRPLP--NKLNANQGGFENGE 274
           QC  C K F+  S  ++H++ HT  K +      K  ++S  L    +++  +  ++   
Sbjct: 242 QCDVCGKIFRKNSYFVRHQRSHTGQKPYICNECGKSFSKSSHLAVHQRIHTGEKPYKCNL 301

Query: 275 IGES-EENNPLDVHSIYIV---PFQCPKCEKCFESEQILNEHSCFAARSGKIPSRFKRSY 330
            G+S  +   L +H        PF+C +C K F+    L  H    A  GK P       
Sbjct: 302 CGKSFSQRVHLRLHQTVHTGERPFKCNECGKTFKRSSNLTVHQVIHA--GKKP------- 352

Query: 331 NYKTIVKKILAKLKRARSKKLDN--FQSEKKVFKKSFLRNCDLISGEQSSEQTQRTFVGS 388
            YK     +  K  R RS  + +    S +K +K      C  +  ++SS          
Sbjct: 353 -YKC---DVCGKAFRHRSNLVCHRRIHSGEKQYK---CNECGKVFSKRSS---------- 395

Query: 389 LGKHGTYKTIGNRKKKTLTLPFSWQNMGKNLKGILTTENILSIDNSVNKKDLSI-CGSSG 447
           L  H        R+  T+  P      GK    + +  + L++   ++    +  C   G
Sbjct: 396 LAVH--------RRIHTVEKPCKCNECGK----VFSKRSSLAVHQRIHTGQKTYKCNKCG 443

Query: 448 EEFFNNCEVLQCGFSVPRENIRTRHKICPCDKCEKVFPSISKLKRHYLIHTGQRPFGCNI 507
           + +  +  +           I T  K   C++C KVF   S+L  H  IHTG++P+ CN 
Sbjct: 444 KVYSKHSHL------AVHWRIHTGEKAYKCNECGKVFSIHSRLAAHQRIHTGEKPYKCNE 497

Query: 508 CGKSFRQSAHLKRHEQTHNEKSPY-ASLCQVEFGNFNNLSNHSGNNVNYNASQQCQAPGV 566
           CGK F Q + L  H + H  + PY    C   F + +  + H   +            G 
Sbjct: 498 CGKVFSQHSRLAVHRRIHTGEKPYKCKECGKVFSDRSAFARHRRIHT-----------GE 546

Query: 567 QKYEVSESDQMSGVKAESQDFIPGSTGQPCLPNVLLESEQSNPFCSYSEHQEKNDVFLYR 626
           + Y+  E  ++                          S+ S        H  +     Y+
Sbjct: 547 KPYKCKECGKVF-------------------------SQCSRLTVHRRIHSGEKP---YK 578

Query: 627 CSVCAKSFRSPSKLERHYLIHAGQKPFECSVCGKTFRQAPHWKRHQLTHFKERP 680
           C+ C K +   S L  H  +H G+KP++C  CGK F Q     RHQ  H  E+P
Sbjct: 579 CNECGKVYSQYSHLVGHRRVHTGEKPYKCHECGKAFNQGSTLNRHQRIHTGEKP 632


>gi|154800445 zinc finger protein 62 homolog [Homo sapiens]
          Length = 840

 Score =  207 bits (527), Expect = 3e-53
 Identities = 177/700 (25%), Positives = 276/700 (39%), Gaps = 131/700 (18%)

Query: 25  RPYVCNICFKHFETPSKLARHYLIHTGQKPFECDVCHKTFRQLVHLERHQLTHS--LPFK 82
           +PY C  C K F   S L  H  IHTG+KP+ECD+C KTF     L  H+  H+   P++
Sbjct: 191 KPYECGECGKAFRNSSGLRVHKRIHTGEKPYECDICGKTFSNSSGLRVHKRIHTGEKPYE 250

Query: 83  CSICQRHFKNLKTFVKHQQLHNETYQNNVKQVRRLLEAKQEKSMYGVYNT---------- 132
           C  C + F   +T + H+ +H         +  +          + V +T          
Sbjct: 251 CDECGKAFITCRTLLNHKSIHFGDKPYKCDECEKSFNYSSLLIQHKVIHTGEKPYECDEC 310

Query: 133 ----------------FTTEERWALHPCSKSDPM-------YSMKRRKNIHACTICGKMF 169
                            T E+ +    C K+           S+   K  H C  CGK F
Sbjct: 311 GKAFRNSSGLIVHKRIHTGEKPYKCDVCGKAFSYSSGLAVHKSIHPGKKAHECKECGKSF 370

Query: 170 PSQSKLDRHVLIHTGQRPFKCVLCTKSFRQSTHLKIHQLTHSEERPFQCCFCQKGFKIQS 229
              S L +H  IHTG+RP+ C +C K+FR +  LK+H+  H+ E+P++C  C K +  +S
Sbjct: 371 SYNSLLLQHRTIHTGERPYVCDVCGKTFRNNAGLKVHRRLHTGEKPYKCDVCGKAYISRS 430

Query: 230 KLLKHKQIHTRNKAFRALLLKKRRTESRPLP--NKLNANQGGFENGEIGESEENNP-LDV 286
            L  HK IH   K ++    +K    S  L    +++  +  F   E G++  NN  L V
Sbjct: 431 SLKNHKGIHLGEKPYKCSYCEKSFNYSSALEQHKRIHTREKPFGCDECGKAFRNNSGLKV 490

Query: 287 HSIYIV---PFQCPKCEKCFESEQILNEHSCFAARSGKIPSRF----KRSYNYKTIVKKI 339
           H        P++C +C K + S   L  H   +   G+ P +     K    Y+T+    
Sbjct: 491 HKRIHTGERPYKCEECGKAYISLSSLINHK--SVHPGEKPFKCDECEKAFITYRTLT--- 545

Query: 340 LAKLKRARSKKLDNFQSEKKVFKKSFLRNCDLISGEQSSEQTQRTFVGSLGKHGTYKTIG 399
                           + KKV        CD+        +    +   L +H       
Sbjct: 546 ----------------NHKKVHLGEKPYKCDVC-------EKSFNYTSLLSQH------- 575

Query: 400 NRKKKTLTLPFSWQNMGKNLKGILTTENILSIDNSVNKKDLSICGSSGEEFFNNCEVLQC 459
            R+  T   P+      K  +   + +    I       +  +CG +   + ++  ++  
Sbjct: 576 -RRVHTREKPYECDRCEKVFRNNSSLKVHKRIHTGERPYECDVCGKA---YISHSSLINH 631

Query: 460 GFSVPRENIRTRHKICPCDKCEKVFPSISKLKRHYLIHTGQRPFGCNICGKSFRQSAHLK 519
             + P +   T      CD+C K F S   L  H  +H G++PF C  CGKSF  S+ L 
Sbjct: 632 KSTHPGKTPHT------CDECGKAFFSSRTLISHKRVHLGEKPFKCVECGKSFSYSSLLS 685

Query: 520 RHEQTHNEKSPY-ASLCQVEFGNFNNLSNHSGNNVNYNASQQCQAPGVQKYEVSESDQMS 578
           +H++ H  + PY    C   F N + L+ H   +            G + YE  E     
Sbjct: 686 QHKRIHTGEKPYVCDRCGKAFRNSSGLTVHKRIHT-----------GEKPYECDE----- 729

Query: 579 GVKAESQDFIPGSTGQPCLPNVLLESEQSNPFCSYSEHQEKNDVFLYRCSVCAKSFRSPS 638
                         G+  + +  L + +S        HQ K     Y C  C KSF   S
Sbjct: 730 -------------CGKAYISHSSLINHKS-------VHQGKQP---YNCE-CGKSFNYRS 765

Query: 639 KLERHYLIHAGQKPFECSVCGKTFRQAPHWKRHQLTHFKE 678
            L++H  IH G+KP+ C+ CGK F    +  +H+ TH  E
Sbjct: 766 VLDQHKRIHTGKKPYRCNECGKAFNIRSNLTKHKRTHTGE 805



 Score =  206 bits (525), Expect = 4e-53
 Identities = 181/682 (26%), Positives = 276/682 (40%), Gaps = 126/682 (18%)

Query: 29  CNICFKHFETPSKLARHYLIHTGQKPFECDVCHKTFRQLVHLERHQLTHS--LPFKCSIC 86
           C+ C K F   S L +H  IHTG+KP+EC  C K FR    L  H+  H+   P++C IC
Sbjct: 167 CDECGKSFNYSSVLDQHKRIHTGEKPYECGECGKAFRNSSGLRVHKRIHTGEKPYECDIC 226

Query: 87  QRHFKNLKTFVKHQQLHNETYQNNVKQVRRLLEAKQEKSMYGVYNTFTTEERWALHPCSK 146
            + F N      H+++H                              T E+ +    C K
Sbjct: 227 GKTFSNSSGLRVHKRIH------------------------------TGEKPYECDECGK 256

Query: 147 SD-PMYSMKRRKNIH------ACTICGKMFPSQSKLDRHVLIHTGQRPFKCVLCTKSFRQ 199
           +     ++   K+IH       C  C K F   S L +H +IHTG++P++C  C K+FR 
Sbjct: 257 AFITCRTLLNHKSIHFGDKPYKCDECEKSFNYSSLLIQHKVIHTGEKPYECDECGKAFRN 316

Query: 200 STHLKIHQLTHSEERPFQCCFCQKGFKIQSKLLKHKQIHTRNKA-----------FRALL 248
           S+ L +H+  H+ E+P++C  C K F   S L  HK IH   KA           + +LL
Sbjct: 317 SSGLIVHKRIHTGEKPYKCDVCGKAFSYSSGLAVHKSIHPGKKAHECKECGKSFSYNSLL 376

Query: 249 LKKRRTESRPLPNKLNANQGGFENGEIGESEENNPLDVHSIYIV---PFQCPKCEKCFES 305
           L+ R   +   P   +     F N        N  L VH        P++C  C K + S
Sbjct: 377 LQHRTIHTGERPYVCDVCGKTFRN--------NAGLKVHRRLHTGEKPYKCDVCGKAYIS 428

Query: 306 EQILNEHSCFAARSGKIP---SRFKRSYNYKTIVKKILAKLKRARSKKLDNFQSEKKVFK 362
              L  H       G+ P   S  ++S+NY + +++   K    R K     +  K    
Sbjct: 429 RSSLKNHK--GIHLGEKPYKCSYCEKSFNYSSALEQ--HKRIHTREKPFGCDECGKAFRN 484

Query: 363 KSFLRNCDLI-SGEQ--SSEQTQRTFVGSLGKHGTYKTIGNRKKKTLTLPFSWQNMGKNL 419
            S L+    I +GE+    E+  + ++ SL     +K++   +K     PF      K  
Sbjct: 485 NSGLKVHKRIHTGERPYKCEECGKAYI-SLSSLINHKSVHPGEK-----PFKCDECEKAF 538

Query: 420 KGILTTENILSIDNSVNKKDLSICGSSGEEFFNNCEVLQCGFSVPRENIRTRHKICPCDK 479
               T  N   +          +C    E+ FN   +L          + TR K   CD+
Sbjct: 539 ITYRTLTNHKKVHLGEKPYKCDVC----EKSFNYTSLLS-----QHRRVHTREKPYECDR 589

Query: 480 CEKVFPSISKLKRHYLIHTGQRPFGCNICGKSFRQSAHLKRHEQTHNEKSPYA-SLCQVE 538
           CEKVF + S LK H  IHTG+RP+ C++CGK++   + L  H+ TH  K+P+    C   
Sbjct: 590 CEKVFRNNSSLKVHKRIHTGERPYECDVCGKAYISHSSLINHKSTHPGKTPHTCDECGKA 649

Query: 539 FGNFNNLSNHSGNNVNYNASQQCQAPGVQKYEVSESDQMSGVKAESQDFIPGSTGQPCLP 598
           F +   L +H   ++     + C        E  +S   S + ++ +    G        
Sbjct: 650 FFSSRTLISHKRVHLGEKPFK-C-------VECGKSFSYSSLLSQHKRIHTGEKP----- 696

Query: 599 NVLLESEQSNPFCSYSEHQEKNDVFLYRCSVCAKSFRSPSKLERHYLIHAGQKPFECSVC 658
                                     Y C  C K+FR+ S L  H  IH G+KP+EC  C
Sbjct: 697 --------------------------YVCDRCGKAFRNSSGLTVHKRIHTGEKPYECDEC 730

Query: 659 GKTFRQAPHWKRHQLTHFKERP 680
           GK +        H+  H  ++P
Sbjct: 731 GKAYISHSSLINHKSVHQGKQP 752



 Score =  205 bits (521), Expect = 1e-52
 Identities = 185/701 (26%), Positives = 289/701 (41%), Gaps = 108/701 (15%)

Query: 29  CNICFKHFETPSKLARHYLIHTGQKPFECDVCHKTFRQLVHLERHQLTHS--LPFKCSIC 86
           C+ C K F+  S+L +H ++HTG+K +ECD C  TFR    L  H+  H+   P+KC  C
Sbjct: 83  CDECGKSFKYNSRLVQHKIMHTGEKRYECDDCGGTFRSSSSLRVHKRIHTGEKPYKCEEC 142

Query: 87  QRHFKNLKTFVKHQQLHNE-------------TYQNNVKQVRRLL------------EAK 121
            + + +  + + H+  H+               Y + + Q +R+             +A 
Sbjct: 143 GKAYMSYSSLINHKSTHSGEKNCKCDECGKSFNYSSVLDQHKRIHTGEKPYECGECGKAF 202

Query: 122 QEKSMYGVYNTFTTEER-WALHPCSKSDPMYS-MKRRKNIHA------CTICGKMFPSQS 173
           +  S   V+    T E+ +    C K+    S ++  K IH       C  CGK F +  
Sbjct: 203 RNSSGLRVHKRIHTGEKPYECDICGKTFSNSSGLRVHKRIHTGEKPYECDECGKAFITCR 262

Query: 174 KLDRHVLIHTGQRPFKCVLCTKSFRQSTHLKIHQLTHSEERPFQCCFCQKGFKIQSKLLK 233
            L  H  IH G +P+KC  C KSF  S+ L  H++ H+ E+P++C  C K F+  S L+ 
Sbjct: 263 TLLNHKSIHFGDKPYKCDECEKSFNYSSLLIQHKVIHTGEKPYECDECGKAFRNSSGLIV 322

Query: 234 HKQIHTRNKAFRALLLKKRRTESRPLP--NKLNANQGGFENGEIGESEENNPLDVHSIYI 291
           HK+IHT  K ++  +  K  + S  L     ++  +   E  E G+S   N L +    I
Sbjct: 323 HKRIHTGEKPYKCDVCGKAFSYSSGLAVHKSIHPGKKAHECKECGKSFSYNSLLLQHRTI 382

Query: 292 ----VPFQCPKCEKCFESEQILNEHSCFAARSGKIPSRFKRSYNYKTIVKKILAKLKRAR 347
                P+ C  C K F +   L  H      +G+ P        YK  V    A + R+ 
Sbjct: 383 HTGERPYVCDVCGKTFRNNAGLKVHR--RLHTGEKP--------YKCDVCG-KAYISRSS 431

Query: 348 SKKLDNFQSEKKVFKKSFLRNCDLISGEQSSEQTQRTFVGSLGKHGTYKTIGNRKKKTLT 407
            K        +K +K S+       S   SS   Q            +K I  R+K    
Sbjct: 432 LKNHKGIHLGEKPYKCSYCEK----SFNYSSALEQ------------HKRIHTREK---- 471

Query: 408 LPFSWQNMGK---NLKGILTTENILSIDNSVNKKDLSICGSSGEEFFNNCEVLQCGFSVP 464
            PF     GK   N  G+   + I + +          C   G+ + +   ++       
Sbjct: 472 -PFGCDECGKAFRNNSGLKVHKRIHTGERPYK------CEECGKAYISLSSLIN------ 518

Query: 465 RENIRTRHKICPCDKCEKVFPSISKLKRHYLIHTGQRPFGCNICGKSFRQSAHLKRHEQT 524
            +++    K   CD+CEK F +   L  H  +H G++P+ C++C KSF  ++ L +H + 
Sbjct: 519 HKSVHPGEKPFKCDECEKAFITYRTLTNHKKVHLGEKPYKCDVCEKSFNYTSLLSQHRRV 578

Query: 525 HNEKSPY-ASLCQVEFGNFNNLSNHSGNNVNYNASQQCQAPGVQKYEVSESDQMSGVKAE 583
           H  + PY    C+  F N ++L  H   +       +C   G  K  +S S  ++     
Sbjct: 579 HTREKPYECDRCEKVFRNNSSLKVHKRIHTG-ERPYECDVCG--KAYISHSSLINHKSTH 635

Query: 584 SQDFIPGSTGQPCLPNVLLESEQSNPFCSYSEHQEKNDVFL----YRCSVCAKSFRSPSK 639
                PG T   C        E    F S         V L    ++C  C KSF   S 
Sbjct: 636 -----PGKTPHTC-------DECGKAFFSSRTLISHKRVHLGEKPFKCVECGKSFSYSSL 683

Query: 640 LERHYLIHAGQKPFECSVCGKTFRQAPHWKRHQLTHFKERP 680
           L +H  IH G+KP+ C  CGK FR +     H+  H  E+P
Sbjct: 684 LSQHKRIHTGEKPYVCDRCGKAFRNSSGLTVHKRIHTGEKP 724



 Score =  195 bits (496), Expect = 1e-49
 Identities = 149/562 (26%), Positives = 253/562 (45%), Gaps = 74/562 (13%)

Query: 24  NRPYVCNICFKHFETPSKLARHYLIHTGQKPFECDVCHKTFRQLVHLERHQLTHS--LPF 81
           ++PY C+ C K F   S L +H +IHTG+KP+ECD C K FR    L  H+  H+   P+
Sbjct: 274 DKPYKCDECEKSFNYSSLLIQHKVIHTGEKPYECDECGKAFRNSSGLIVHKRIHTGEKPY 333

Query: 82  KCSICQRHFKNLKTFVKHQQLHNETYQNNVKQVRRLLEAKQEKSMYGVYNTFTTEERWAL 141
           KC +C + F        H+ +H     +  K+  +             YN+   + R   
Sbjct: 334 KCDVCGKAFSYSSGLAVHKSIHPGKKAHECKECGKSFS----------YNSLLLQHR--- 380

Query: 142 HPCSKSDPMYSMKRRKNIHACTICGKMFPSQSKLDRHVLIHTGQRPFKCVLCTKSFRQST 201
                     ++   +  + C +CGK F + + L  H  +HTG++P+KC +C K++   +
Sbjct: 381 ----------TIHTGERPYVCDVCGKTFRNNAGLKVHRRLHTGEKPYKCDVCGKAYISRS 430

Query: 202 HLKIHQLTHSEERPFQCCFCQKGFKIQSKLLKHKQIHTRNKAFRALLLKK--RRTESRPL 259
            LK H+  H  E+P++C +C+K F   S L +HK+IHTR K F      K  R      +
Sbjct: 431 SLKNHKGIHLGEKPYKCSYCEKSFNYSSALEQHKRIHTREKPFGCDECGKAFRNNSGLKV 490

Query: 260 PNKLNANQGGFENGEIGE-----SEENNPLDVHSIYIVPFQCPKCEKCFESEQILNEHSC 314
             +++  +  ++  E G+     S   N   VH     PF+C +CEK F + + L  H  
Sbjct: 491 HKRIHTGERPYKCEECGKAYISLSSLINHKSVHP-GEKPFKCDECEKAFITYRTLTNHK- 548

Query: 315 FAARSGKIPSR---FKRSYNYKTIV---KKILAKLKR---ARSKKLDNFQSEKKVFK--- 362
                G+ P +    ++S+NY +++   +++  + K     R +K+    S  KV K   
Sbjct: 549 -KVHLGEKPYKCDVCEKSFNYTSLLSQHRRVHTREKPYECDRCEKVFRNNSSLKVHKRIH 607

Query: 363 ------------KSFLRNCDLISGEQSSEQTQRTFVGSLGK--HGTYKTIGNRKKKTLTL 408
                       K+++ +  LI+ + +            GK    +   I +++      
Sbjct: 608 TGERPYECDVCGKAYISHSSLINHKSTHPGKTPHTCDECGKAFFSSRTLISHKRVHLGEK 667

Query: 409 PFSWQNMGKNLKGILTTENILSIDNSVNKKDLS-ICGSSGEEFFNNCEVLQCGFSVPREN 467
           PF     GK+     +  ++LS    ++  +   +C   G+ F N+      G +V  + 
Sbjct: 668 PFKCVECGKS----FSYSSLLSQHKRIHTGEKPYVCDRCGKAFRNS-----SGLTV-HKR 717

Query: 468 IRTRHKICPCDKCEKVFPSISKLKRHYLIHTGQRPFGCNICGKSFRQSAHLKRHEQTHNE 527
           I T  K   CD+C K + S S L  H  +H G++P+ C  CGKSF   + L +H++ H  
Sbjct: 718 IHTGEKPYECDECGKAYISHSSLINHKSVHQGKQPYNCE-CGKSFNYRSVLDQHKRIHTG 776

Query: 528 KSPY-ASLCQVEFGNFNNLSNH 548
           K PY  + C   F   +NL+ H
Sbjct: 777 KKPYRCNECGKAFNIRSNLTKH 798



 Score =  186 bits (472), Expect = 6e-47
 Identities = 167/647 (25%), Positives = 253/647 (39%), Gaps = 130/647 (20%)

Query: 52  QKPFECDVCHKTFRQLVHLERHQLTHS--LPFKCSICQRHFKNLKTFVKHQQLHNETYQN 109
           +K  +CD C K+F+    L +H++ H+    ++C  C   F++  +   H+++H      
Sbjct: 78  KKLHKCDECGKSFKYNSRLVQHKIMHTGEKRYECDDCGGTFRSSSSLRVHKRIH------ 131

Query: 110 NVKQVRRLLEAKQEKSMYGVYNTFTTEERWALHPCSKSDPMYS-MKRRKNIHA------C 162
                                   T E+ +    C K+   YS +   K+ H+      C
Sbjct: 132 ------------------------TGEKPYKCEECGKAYMSYSSLINHKSTHSGEKNCKC 167

Query: 163 TICGKMFPSQSKLDRHVLIHTGQRPFKCVLCTKSFRQSTHLKIHQLTHSEERPFQCCFCQ 222
             CGK F   S LD+H  IHTG++P++C  C K+FR S+ L++H+  H+ E+P++C  C 
Sbjct: 168 DECGKSFNYSSVLDQHKRIHTGEKPYECGECGKAFRNSSGLRVHKRIHTGEKPYECDICG 227

Query: 223 KGFKIQSKLLKHKQIHTRNKAFRALLLKKRRTESRPLPNKLNANQGGFENGEIGESEENN 282
           K F   S L  HK+IHT  K +      K     R L N  + + G              
Sbjct: 228 KTFSNSSGLRVHKRIHTGEKPYECDECGKAFITCRTLLNHKSIHFGD------------- 274

Query: 283 PLDVHSIYIVPFQCPKCEKCFESEQILNEHSCFAARSGKIPSRFKRSYNYKTIVKKILAK 342
                     P++C +CEK F    +L +H        K+    ++ Y      K     
Sbjct: 275 ---------KPYKCDECEKSFNYSSLLIQH--------KVIHTGEKPYECDECGKAFRNS 317

Query: 343 LKRARSKKLDNFQSEKKVFKKSFLRNCDLISGEQSSEQTQRTFVGSLGKHGTYKTIGNRK 402
                 K++   +   K         CD+           + F  S G    +K+I   K
Sbjct: 318 SGLIVHKRIHTGEKPYK---------CDVCG---------KAFSYSSGL-AVHKSIHPGK 358

Query: 403 K----KTLTLPFSWQNMGKNLKGILTTENILSIDNSVNKKDLSICGSSGEEFFNNCEVLQ 458
           K    K     FS+ ++    + I T E               +C   G+ F NN     
Sbjct: 359 KAHECKECGKSFSYNSLLLQHRTIHTGERPY------------VCDVCGKTFRNN----- 401

Query: 459 CGFSVPRENIRTRHKICPCDKCEKVFPSISKLKRHYLIHTGQRPFGCNICGKSFRQSAHL 518
            G  V R  + T  K   CD C K + S S LK H  IH G++P+ C+ C KSF  S+ L
Sbjct: 402 AGLKVHR-RLHTGEKPYKCDVCGKAYISRSSLKNHKGIHLGEKPYKCSYCEKSFNYSSAL 460

Query: 519 KRHEQTHNEKSPY-ASLCQVEFGNFNNLSNHSGNNVNYNASQQCQAPGVQKYEVSESDQM 577
           ++H++ H  + P+    C   F N + L  H   +       +C+  G     +S     
Sbjct: 461 EQHKRIHTREKPFGCDECGKAFRNNSGLKVHKRIHTG-ERPYKCEECGKAYISLSSLINH 519

Query: 578 SGVKAESQDFIPGSTGQPCLPNVLLESEQSNPFCSYSEHQEKNDVFL----YRCSVCAKS 633
             V        PG     C        E    F +Y        V L    Y+C VC KS
Sbjct: 520 KSVH-------PGEKPFKC-------DECEKAFITYRTLTNHKKVHLGEKPYKCDVCEKS 565

Query: 634 FRSPSKLERHYLIHAGQKPFECSVCGKTFRQAPHWKRHQLTHFKERP 680
           F   S L +H  +H  +KP+EC  C K FR     K H+  H  ERP
Sbjct: 566 FNYTSLLSQHRRVHTREKPYECDRCEKVFRNNSSLKVHKRIHTGERP 612



 Score =  162 bits (410), Expect = 1e-39
 Identities = 139/553 (25%), Positives = 228/553 (41%), Gaps = 116/553 (20%)

Query: 22  PRNRPYVCNICFKHFETPSKLARHYLIHTGQKPFECDVCHKTFRQLVHLERHQLTHS--L 79
           P  + + C  C K F   S L +H  IHTG++P+ CDVC KTFR    L+ H+  H+   
Sbjct: 356 PGKKAHECKECGKSFSYNSLLLQHRTIHTGERPYVCDVCGKTFRNNAGLKVHRRLHTGEK 415

Query: 80  PFKCSICQRHFKNLKTFVKHQQLHNETYQNNVKQVRRLLEAKQEKSMYGVYNTFTTEERW 139
           P+KC +C + + +  +   H+ +H              L  K  K  Y            
Sbjct: 416 PYKCDVCGKAYISRSSLKNHKGIH--------------LGEKPYKCSY------------ 449

Query: 140 ALHPCSKS-DPMYSMKRRKNIH------ACTICGKMFPSQSKLDRHVLIHTGQRPFKCVL 192
               C KS +   ++++ K IH       C  CGK F + S L  H  IHTG+RP+KC  
Sbjct: 450 ----CEKSFNYSSALEQHKRIHTREKPFGCDECGKAFRNNSGLKVHKRIHTGERPYKCEE 505

Query: 193 CTKSFRQSTHLKIHQLTHSEERPFQCCFCQKGFKIQSKLLKHKQIHTRNKAFR------- 245
           C K++   + L  H+  H  E+PF+C  C+K F     L  HK++H   K ++       
Sbjct: 506 CGKAYISLSSLINHKSVHPGEKPFKCDECEKAFITYRTLTNHKKVHLGEKPYKCDVCEKS 565

Query: 246 ----ALLLKKRRTESRPLPNKLNANQGGFENGEIGESEENNPLDVHSIYIV---PFQCPK 298
               +LL + RR  +R  P + +  +  F N        N+ L VH        P++C  
Sbjct: 566 FNYTSLLSQHRRVHTREKPYECDRCEKVFRN--------NSSLKVHKRIHTGERPYECDV 617

Query: 299 CEKCFESEQILNEHSCFAARSGKIPSRFKRSYNYKTIVKKILAKLKRARSKKLDNFQSEK 358
           C K + S   L  H   +   GK P                                   
Sbjct: 618 CGKAYISHSSLINHK--STHPGKTPHTCDEC----------------------------- 646

Query: 359 KVFKKSFLRNCDLISGEQSSEQTQRTFVGSLGKHGTYKTIGNRKKKTLT--LPFSWQNMG 416
               K+F  +  LIS ++     +       GK  +Y ++ ++ K+  T   P+     G
Sbjct: 647 ---GKAFFSSRTLISHKRVHLGEKPFKCVECGKSFSYSSLLSQHKRIHTGEKPYVCDRCG 703

Query: 417 K---NLKGILTTENILSIDNSVNKKDLSICGSSGEEFFNNCEVLQCGFSVPRENIRTRHK 473
           K   N  G+   + I + +          C   G+ + ++  ++        +++    +
Sbjct: 704 KAFRNSSGLTVHKRIHTGEKPYE------CDECGKAYISHSSLIN------HKSVHQGKQ 751

Query: 474 ICPCDKCEKVFPSISKLKRHYLIHTGQRPFGCNICGKSFRQSAHLKRHEQTHNEKSPYAS 533
              C+ C K F   S L +H  IHTG++P+ CN CGK+F   ++L +H++TH  +    S
Sbjct: 752 PYNCE-CGKSFNYRSVLDQHKRIHTGKKPYRCNECGKAFNIRSNLTKHKRTHTGEE---S 807

Query: 534 LCQVEFGNFNNLS 546
           L  +  G+++  S
Sbjct: 808 LNVIYVGSYSGTS 820



 Score =  119 bits (299), Expect = 7e-27
 Identities = 118/516 (22%), Positives = 212/516 (41%), Gaps = 95/516 (18%)

Query: 178 HVLIHTGQRPFKCVLCTKSFRQSTHLKIHQLTHSEERPFQCCFCQKGFKIQSKLLKHKQI 237
           H  +  GQR  +     ++   +++  + Q T++ ++  +C  C K FK  S+L++HK +
Sbjct: 43  HQTMPIGQRGSEQGKRVENINGTSYPSLQQKTNAVKKLHKCDECGKSFKYNSRLVQHKIM 102

Query: 238 HTRNKAFRALLLKKRRTESRPLPNKLNANQGGFENGEIGESEENNPLDVHSIYIV---PF 294
           HT  K +                     +  G      G    ++ L VH        P+
Sbjct: 103 HTGEKRYEC-------------------DDCG------GTFRSSSSLRVHKRIHTGEKPY 137

Query: 295 QCPKCEKCFES-EQILNEHSCFAARSGKIPSRFKRSYNYKTIVKKILAKLKRARSKKLDN 353
           +C +C K + S   ++N  S  +           +S+NY +++ +               
Sbjct: 138 KCEECGKAYMSYSSLINHKSTHSGEKNCKCDECGKSFNYSSVLDQ--------------- 182

Query: 354 FQSEKKVFKKSFLRNCDLISGEQSSE--QTQRTFVGSLGKHGTYKTIGNRKKKTLTLPFS 411
               K++            +GE+  E  +  + F  S G    +K I   +K     P+ 
Sbjct: 183 ---HKRIH-----------TGEKPYECGECGKAFRNSSGLR-VHKRIHTGEK-----PYE 222

Query: 412 WQNMGK---NLKGILTTENILSIDNSVNKKDLSICGSSGEEFFNNCEVLQCGFSVPRENI 468
               GK   N  G+   + I + +          C   G+ F      + C   +  ++I
Sbjct: 223 CDICGKTFSNSSGLRVHKRIHTGEKPYE------CDECGKAF------ITCRTLLNHKSI 270

Query: 469 RTRHKICPCDKCEKVFPSISKLKRHYLIHTGQRPFGCNICGKSFRQSAHLKRHEQTHNEK 528
               K   CD+CEK F   S L +H +IHTG++P+ C+ CGK+FR S+ L  H++ H  +
Sbjct: 271 HFGDKPYKCDECEKSFNYSSLLIQHKVIHTGEKPYECDECGKAFRNSSGLIVHKRIHTGE 330

Query: 529 SPY-ASLCQVEFGNFNNLSNHSGNNVNYNASQQCQAPGVQKYEVSESDQMSGVKAESQDF 587
            PY   +C   F   + L+ H   +           PG + +E  E  +     +     
Sbjct: 331 KPYKCDVCGKAFSYSSGLAVHKSIH-----------PGKKAHECKECGKSFSYNSLLLQH 379

Query: 588 IPGSTGQ-PCLPNVLLESEQSNPFCSYSEHQEKNDVFLYRCSVCAKSFRSPSKLERHYLI 646
               TG+ P + +V  ++ ++N            +   Y+C VC K++ S S L+ H  I
Sbjct: 380 RTIHTGERPYVCDVCGKTFRNNAGLKVHRRLHTGEK-PYKCDVCGKAYISRSSLKNHKGI 438

Query: 647 HAGQKPFECSVCGKTFRQAPHWKRHQLTHFKERPQG 682
           H G+KP++CS C K+F  +   ++H+  H +E+P G
Sbjct: 439 HLGEKPYKCSYCEKSFNYSSALEQHKRIHTREKPFG 474



 Score = 60.5 bits (145), Expect = 5e-09
 Identities = 38/133 (28%), Positives = 57/133 (42%), Gaps = 29/133 (21%)

Query: 25  RPYVCNICFKHFETPSKLARHYLIHTGQKPFECDVCHKTF--------RQLVH------- 69
           +PYVC+ C K F   S L  H  IHTG+KP+ECD C K +         + VH       
Sbjct: 695 KPYVCDRCGKAFRNSSGLTVHKRIHTGEKPYECDECGKAYISHSSLINHKSVHQGKQPYN 754

Query: 70  ------------LERHQLTHS--LPFKCSICQRHFKNLKTFVKHQQLHNETYQNNVKQVR 115
                       L++H+  H+   P++C+ C + F       KH++ H      NV  V 
Sbjct: 755 CECGKSFNYRSVLDQHKRIHTGKKPYRCNECGKAFNIRSNLTKHKRTHTGEESLNVIYVG 814

Query: 116 RLLEAKQEKSMYG 128
                 Q+++  G
Sbjct: 815 SYSGTSQKRTYEG 827


>gi|115511042 zinc finger protein 493 isoform 1 [Homo sapiens]
          Length = 646

 Score =  207 bits (526), Expect = 3e-53
 Identities = 147/523 (28%), Positives = 241/523 (46%), Gaps = 44/523 (8%)

Query: 25  RPYVCNICFKHFETPSKLARHYLIHTGQKPFECDVCHKTFRQLVHLERHQLTHS--LPFK 82
           +PY C  C   F   S L RH LIHT +KP++C+   KTF Q   L  H++ H+   P+K
Sbjct: 135 KPYKCEECGTSFYQFSYLTRHKLIHTREKPYKCEQYGKTFNQSSTLTGHKIIHNGEKPYK 194

Query: 83  CSICQRHFKNLKTFVKHQQLHNETYQNNVKQVRRLLEAKQEKSMYGVYNTFTTEER-WAL 141
           C  C + F    T  KH+ +H E   +  ++     +A +E S    +    T E+ +  
Sbjct: 195 CEECGKAFSIFSTPTKHKIIHTEEKSHRCEEY---CKAYKESSHLTTHKRIHTGEKPYKC 251

Query: 142 HPCSKSDPMYSMKRRKNI-------HACTICGKMFPSQSKLDRHVLIHTGQRPFKCVLCT 194
             C K+  ++S   +  I       H C  CGK +   S L  H  IHTG++P+KC  C 
Sbjct: 252 EECGKAFSIFSTLTKHKIIHTEEKSHRCEECGKAYKESSHLTTHKRIHTGEKPYKCEECG 311

Query: 195 KSFRQSTHLKIHQLTHSEERPFQCCFCQKGFKIQSKLLKHKQIHTRNKAFRALLLKKRRT 254
           K+F   + L  H++ H+EE+P++C  C K FK  S L KH+ IHT  K ++     K   
Sbjct: 312 KTFSVFSILTKHKIIHTEEKPYKCEECGKAFKRSSTLTKHRIIHTEEKPYKCEECGKAFN 371

Query: 255 ESRPLP--NKLNANQGGFENGEIGES-EENNPLDVHSIYIV---PFQCPKCEKCFESEQI 308
           +S  L     ++  +  ++  E G++ + ++ L +H +      P++C +C K F     
Sbjct: 372 QSSTLSIHKIIHTGEKPYKCEECGKAFKRSSTLTIHKMIHTGEKPYKCEECGKAFNRSSH 431

Query: 309 LNEHSCFAARSGKIPSRFKRSYNYKTIVKKILAKLKRARSKKLDNFQSEKKVFKKSFLRN 368
           L  H      +G  P + K      ++   +         KK    +   K F +S + +
Sbjct: 432 LTTHK--RIHTGHKPYKCKECGKSFSVFSTLTKHKIIHTDKKPYKCEECGKAFNRSSILS 489

Query: 369 CD--LISGEQSSEQTQRTFVGSLGKHGTYKTIGNRKKKTLTLPFSWQNMGK--NLKGILT 424
               + +GE+  +  +    G   K  ++   G+++  ++  P+  +  GK  ++   LT
Sbjct: 490 IHKKIHTGEKPYKCEE---CGKAFKRSSHLA-GHKQIHSVQKPYKCEECGKAFSIFSTLT 545

Query: 425 TENILSIDNSVNKKDLSICGSSGEEF--FNNCEVLQCGFSVPRENIRTRHKICPCDKCEK 482
              I+  +    K     C   G+ F  F+N            + I T  K C C++C K
Sbjct: 546 KHKIIHTEEKPYK-----CEKCGKTFYRFSNLNT--------HKIIHTGEKPCKCEECGK 592

Query: 483 VFPSISKLKRHYLIHTGQRPFGCNICGKSFRQSAHLKRHEQTH 525
            F   S L +H LIHTG +P+ C  CGK+FR+S+HL RH+  H
Sbjct: 593 AFNHSSNLIKHKLIHTGDKPYKCEACGKAFRRSSHLSRHKIIH 635



 Score =  203 bits (517), Expect = 4e-52
 Identities = 182/700 (26%), Positives = 286/700 (40%), Gaps = 133/700 (19%)

Query: 23  RNRPYVCNICFKHFETPSKLARHYLIHTGQKPFECDVCHKTFRQLVHLERHQLTH--SLP 80
           +++ + C+   K F       RH   HTG+KPF+C  C K+F  L+HL +H+  H     
Sbjct: 22  QSKIFQCDKYVKVFHKLLNSNRHNTKHTGKKPFKCKKCGKSFCMLLHLCQHKRIHIRENS 81

Query: 81  FKCSICQRHFKNLKTFVKHQQLHNETYQNNVKQVRRLLEAKQEKSMYGVYNTFTTEERWA 140
           ++C  C + F    T  +H+++H                               T E+  
Sbjct: 82  YRCEECGKAFIWFSTLTRHRRVH-------------------------------TGEKSY 110

Query: 141 LHPCSKSDPMYS-MKRRKNIHA------CTICGKMFPSQSKLDRHVLIHTGQRPFKCVLC 193
            + C KS    S +   K IH       C  CG  F   S L RH LIHT ++P+KC   
Sbjct: 111 KYECGKSFNQDSNLTTHKRIHTGQKPYKCEECGTSFYQFSYLTRHKLIHTREKPYKCEQY 170

Query: 194 TKSFRQSTHLKIHQLTHSEERPFQCCFCQKGFKIQSKLLKHKQIHTRNKAFRALLLKKRR 253
            K+F QS+ L  H++ H+ E+P++C  C K F I S   KHK IHT  K+ R     K  
Sbjct: 171 GKTFNQSSTLTGHKIIHNGEKPYKCEECGKAFSIFSTPTKHKIIHTEEKSHRCEEYCKAY 230

Query: 254 TESRPLP--NKLNANQGGFENGEIGES-EENNPLDVHSIYIV---PFQCPKCEKCFESEQ 307
            ES  L    +++  +  ++  E G++    + L  H I        +C +C K ++   
Sbjct: 231 KESSHLTTHKRIHTGEKPYKCEECGKAFSIFSTLTKHKIIHTEEKSHRCEECGKAYKESS 290

Query: 308 ILNEHSCFAARSGKIPSRFK---RSYNYKTIVKKILAKLKRARSKKLDNFQSEKKVFKKS 364
            L  H      +G+ P + +   ++++  +I+ K   K+     K     +  K   + S
Sbjct: 291 HLTTHK--RIHTGEKPYKCEECGKTFSVFSILTK--HKIIHTEEKPYKCEECGKAFKRSS 346

Query: 365 FLRNCDLISGEQ---SSEQTQRTFVGSLGKHGTYKTIGNRKKKTLTLPFSWQNMGKNLK- 420
            L    +I  E+     E+  + F  S      +K I   +K     P+  +  GK  K 
Sbjct: 347 TLTKHRIIHTEEKPYKCEECGKAFNQS-STLSIHKIIHTGEK-----PYKCEECGKAFKR 400

Query: 421 -GILTTENILSIDNSVNKKDLSICGSSGEEFFNNCEVL---------------QCGFSVP 464
              LT   ++       K     C   G+ F  +  +                +CG S  
Sbjct: 401 SSTLTIHKMIHTGEKPYK-----CEECGKAFNRSSHLTTHKRIHTGHKPYKCKECGKSFS 455

Query: 465 RENIRTRHKIC-------PCDKCEKVFPSISKLKRHYLIHTGQRPFGCNICGKSFRQSAH 517
             +  T+HKI         C++C K F   S L  H  IHTG++P+ C  CGK+F++S+H
Sbjct: 456 VFSTLTKHKIIHTDKKPYKCEECGKAFNRSSILSIHKKIHTGEKPYKCEECGKAFKRSSH 515

Query: 518 LKRHEQTHNEKSPY-ASLCQVEFGNFNNLSNHSGNNVNYNASQQCQAPGVQKYEVSESDQ 576
           L  H+Q H+ + PY    C   F  F+ L+ H   +       +C+  G   Y  S  + 
Sbjct: 516 LAGHKQIHSVQKPYKCEECGKAFSIFSTLTKHKIIHTE-EKPYKCEKCGKTFYRFSNLNT 574

Query: 577 MSGVKAESQDFIPGSTGQ-PCLPNVLLESEQSNPFCSYSEHQEKNDVFLYRCSVCAKSFR 635
              +           TG+ PC                             +C  C K+F 
Sbjct: 575 HKII----------HTGEKPC-----------------------------KCEECGKAFN 595

Query: 636 SPSKLERHYLIHAGQKPFECSVCGKTFRQAPHWKRHQLTH 675
             S L +H LIH G KP++C  CGK FR++ H  RH++ H
Sbjct: 596 HSSNLIKHKLIHTGDKPYKCEACGKAFRRSSHLSRHKIIH 635



 Score =  172 bits (435), Expect = 1e-42
 Identities = 169/669 (25%), Positives = 264/669 (39%), Gaps = 160/669 (23%)

Query: 30  NICFKHFETPSKLARHYLIHTGQKPFECDVCHKTFRQLVHLERHQLTHS--LPFKCSICQ 87
           N C  H E  ++L   YL  T  K F+CD   K F +L++  RH   H+   PFKC  C 
Sbjct: 2   NECNVHKEGYNEL-NQYLTTTQSKIFQCDKYVKVFHKLLNSNRHNTKHTGKKPFKCKKCG 60

Query: 88  RHFKNLKTFVKHQQLHNETYQNNVKQVRRLLEAKQEKSMYGVYNTFTTEERWALHPCSKS 147
           + F  L                                               LH C   
Sbjct: 61  KSFCML-----------------------------------------------LHLCQHK 73

Query: 148 DPMYSMKRRKNIHACTICGKMFPSQSKLDRHVLIHTGQRPFKCVLCTKSFRQSTHLKIHQ 207
                +  R+N + C  CGK F   S L RH  +HTG++ +K   C KSF Q ++L  H+
Sbjct: 74  ----RIHIRENSYRCEECGKAFIWFSTLTRHRRVHTGEKSYKYE-CGKSFNQDSNLTTHK 128

Query: 208 LTHSEERPFQCCFCQKGFKIQSKLLKHKQIHTRNKAFRALLLKKRRTESRPLP-NKLNAN 266
             H+ ++P++C  C   F   S L +HK IHTR K ++     K   +S  L  +K+   
Sbjct: 129 RIHTGQKPYKCEECGTSFYQFSYLTRHKLIHTREKPYKCEQYGKTFNQSSTLTGHKI--- 185

Query: 267 QGGFENGEIGESEENNPLDVHSIYIVPFQCPKCEKCFESEQILNEHSCF-----AARSGK 321
                NGE                  P++C +C K F       +H        + R  +
Sbjct: 186 ---IHNGE-----------------KPYKCEECGKAFSIFSTPTKHKIIHTEEKSHRCEE 225

Query: 322 IPSRFKRSYNYKTIVKKILAKLKRARSKKLDNFQSEKKVFKKSFLRNCDLISGEQSSEQT 381
               +K S ++ T  K+I    K  + ++     S   +F  S L    +I  E+ S + 
Sbjct: 226 YCKAYKES-SHLTTHKRIHTGEKPYKCEECGKAFS---IF--STLTKHKIIHTEEKSHRC 279

Query: 382 QRTFVGSLGKHGTYKTIGNRKKKTLTLPFSWQNMGKNLK--GILTTENILSIDNSVNKKD 439
           +    G   K  ++ T  +++  T   P+  +  GK      ILT   I+  +    K  
Sbjct: 280 EEC--GKAYKESSHLTT-HKRIHTGEKPYKCEECGKTFSVFSILTKHKIIHTEEKPYK-- 334

Query: 440 LSICGSSGEEFFNNCEVLQCGFSVPRENIRTRHKIC-------PCDKCEKVFPSISKLKR 492
                         CE  +CG +  R +  T+H+I         C++C K F   S L  
Sbjct: 335 --------------CE--ECGKAFKRSSTLTKHRIIHTEEKPYKCEECGKAFNQSSTLSI 378

Query: 493 HYLIHTGQRPFGCNICGKSFRQSAHLKRHEQTHNEKSPYASLCQVEFGNFNNLSNHSGNN 552
           H +IHTG++P+ C  CGK+F++S+ L  H+  H  + PY   C+ E G   N S+H   +
Sbjct: 379 HKIIHTGEKPYKCEECGKAFKRSSTLTIHKMIHTGEKPYK--CE-ECGKAFNRSSHLTTH 435

Query: 553 VNYNASQQCQAPGVQKYEVSESDQMSGVKAESQDFIPGSTGQPCLPNVLLESEQSNPFCS 612
              +        G + Y+  E  +   V                             F +
Sbjct: 436 KRIHT-------GHKPYKCKECGKSFSV-----------------------------FST 459

Query: 613 YSEHQE-KNDVFLYRCSVCAKSFRSPSKLERHYLIHAGQKPFECSVCGKTFRQAPHWKRH 671
            ++H+    D   Y+C  C K+F   S L  H  IH G+KP++C  CGK F+++ H   H
Sbjct: 460 LTKHKIIHTDKKPYKCEECGKAFNRSSILSIHKKIHTGEKPYKCEECGKAFKRSSHLAGH 519

Query: 672 QLTHFKERP 680
           +  H  ++P
Sbjct: 520 KQIHSVQKP 528



 Score = 92.8 bits (229), Expect = 9e-19
 Identities = 61/220 (27%), Positives = 96/220 (43%), Gaps = 19/220 (8%)

Query: 479 KCEKVFPSISKLKRHYLIHTGQRPFGCNICGKSFRQSAHLKRHEQTHNEKSPYASLCQVE 538
           +C K F   S L  H  IHTGQ+P+ C  CG SF Q ++L RH+  H  + PY   C+  
Sbjct: 113 ECGKSFNQDSNLTTHKRIHTGQKPYKCEECGTSFYQFSYLTRHKLIHTREKPYK--CEQY 170

Query: 539 FGNFNNLSNHSGNNVNYNASQ--QCQAPGVQKYEVSESDQMSGVKAESQDFIPGSTGQPC 596
              FN  S  +G+ + +N  +  +C+  G      S   +   +  E +          C
Sbjct: 171 GKTFNQSSTLTGHKIIHNGEKPYKCEECGKAFSIFSTPTKHKIIHTEEKS-------HRC 223

Query: 597 LPNVLLESEQSNPFCSYSEHQEKNDVFLYRCSVCAKSFRSPSKLERHYLIHAGQKPFECS 656
                   E S+       H  +     Y+C  C K+F   S L +H +IH  +K   C 
Sbjct: 224 EEYCKAYKESSHLTTHKRIHTGEKP---YKCEECGKAFSIFSTLTKHKIIHTEEKSHRCE 280

Query: 657 VCGKTFRQAPHWKRHQLTHFKERPQ-----GKVVALDSVM 691
            CGK ++++ H   H+  H  E+P      GK  ++ S++
Sbjct: 281 ECGKAYKESSHLTTHKRIHTGEKPYKCEECGKTFSVFSIL 320



 Score = 91.3 bits (225), Expect = 3e-18
 Identities = 53/169 (31%), Positives = 81/169 (47%), Gaps = 11/169 (6%)

Query: 25  RPYVCNICFKHFETPSKLARHYLIHTGQKPFECDVCHKTFRQLVHLERHQLTHSL--PFK 82
           +PY C  C K F   S L+ H  IHTG+KP++C+ C K F++  HL  H+  HS+  P+K
Sbjct: 471 KPYKCEECGKAFNRSSILSIHKKIHTGEKPYKCEECGKAFKRSSHLAGHKQIHSVQKPYK 530

Query: 83  CSICQRHFKNLKTFVKHQQLHNETYQNNVKQVRRLLEAKQEKSMYGVYNTFTTEERWALH 142
           C  C + F    T  KH+ +H E      ++  +        + + + +T   E+     
Sbjct: 531 CEECGKAFSIFSTLTKHKIIHTEEKPYKCEKCGKTFYRFSNLNTHKIIHT--GEKPCKCE 588

Query: 143 PCSKS-DPMYSMKRRKNIHA------CTICGKMFPSQSKLDRHVLIHTG 184
            C K+ +   ++ + K IH       C  CGK F   S L RH +IH G
Sbjct: 589 ECGKAFNHSSNLIKHKLIHTGDKPYKCEACGKAFRRSSHLSRHKIIHIG 637



 Score = 33.1 bits (74), Expect = 0.88
 Identities = 13/28 (46%), Positives = 17/28 (60%)

Query: 24  NRPYVCNICFKHFETPSKLARHYLIHTG 51
           ++PY C  C K F   S L+RH +IH G
Sbjct: 610 DKPYKCEACGKAFRRSSHLSRHKIIHIG 637


>gi|115511044 zinc finger protein 493 isoform 3 [Homo sapiens]
          Length = 774

 Score =  207 bits (526), Expect = 3e-53
 Identities = 147/523 (28%), Positives = 241/523 (46%), Gaps = 44/523 (8%)

Query: 25  RPYVCNICFKHFETPSKLARHYLIHTGQKPFECDVCHKTFRQLVHLERHQLTHS--LPFK 82
           +PY C  C   F   S L RH LIHT +KP++C+   KTF Q   L  H++ H+   P+K
Sbjct: 263 KPYKCEECGTSFYQFSYLTRHKLIHTREKPYKCEQYGKTFNQSSTLTGHKIIHNGEKPYK 322

Query: 83  CSICQRHFKNLKTFVKHQQLHNETYQNNVKQVRRLLEAKQEKSMYGVYNTFTTEER-WAL 141
           C  C + F    T  KH+ +H E   +  ++     +A +E S    +    T E+ +  
Sbjct: 323 CEECGKAFSIFSTPTKHKIIHTEEKSHRCEEY---CKAYKESSHLTTHKRIHTGEKPYKC 379

Query: 142 HPCSKSDPMYSMKRRKNI-------HACTICGKMFPSQSKLDRHVLIHTGQRPFKCVLCT 194
             C K+  ++S   +  I       H C  CGK +   S L  H  IHTG++P+KC  C 
Sbjct: 380 EECGKAFSIFSTLTKHKIIHTEEKSHRCEECGKAYKESSHLTTHKRIHTGEKPYKCEECG 439

Query: 195 KSFRQSTHLKIHQLTHSEERPFQCCFCQKGFKIQSKLLKHKQIHTRNKAFRALLLKKRRT 254
           K+F   + L  H++ H+EE+P++C  C K FK  S L KH+ IHT  K ++     K   
Sbjct: 440 KTFSVFSILTKHKIIHTEEKPYKCEECGKAFKRSSTLTKHRIIHTEEKPYKCEECGKAFN 499

Query: 255 ESRPLP--NKLNANQGGFENGEIGES-EENNPLDVHSIYIV---PFQCPKCEKCFESEQI 308
           +S  L     ++  +  ++  E G++ + ++ L +H +      P++C +C K F     
Sbjct: 500 QSSTLSIHKIIHTGEKPYKCEECGKAFKRSSTLTIHKMIHTGEKPYKCEECGKAFNRSSH 559

Query: 309 LNEHSCFAARSGKIPSRFKRSYNYKTIVKKILAKLKRARSKKLDNFQSEKKVFKKSFLRN 368
           L  H      +G  P + K      ++   +         KK    +   K F +S + +
Sbjct: 560 LTTHK--RIHTGHKPYKCKECGKSFSVFSTLTKHKIIHTDKKPYKCEECGKAFNRSSILS 617

Query: 369 CD--LISGEQSSEQTQRTFVGSLGKHGTYKTIGNRKKKTLTLPFSWQNMGK--NLKGILT 424
               + +GE+  +  +    G   K  ++   G+++  ++  P+  +  GK  ++   LT
Sbjct: 618 IHKKIHTGEKPYKCEE---CGKAFKRSSHLA-GHKQIHSVQKPYKCEECGKAFSIFSTLT 673

Query: 425 TENILSIDNSVNKKDLSICGSSGEEF--FNNCEVLQCGFSVPRENIRTRHKICPCDKCEK 482
              I+  +    K     C   G+ F  F+N            + I T  K C C++C K
Sbjct: 674 KHKIIHTEEKPYK-----CEKCGKTFYRFSNLNT--------HKIIHTGEKPCKCEECGK 720

Query: 483 VFPSISKLKRHYLIHTGQRPFGCNICGKSFRQSAHLKRHEQTH 525
            F   S L +H LIHTG +P+ C  CGK+FR+S+HL RH+  H
Sbjct: 721 AFNHSSNLIKHKLIHTGDKPYKCEACGKAFRRSSHLSRHKIIH 763



 Score =  203 bits (517), Expect = 4e-52
 Identities = 182/700 (26%), Positives = 286/700 (40%), Gaps = 133/700 (19%)

Query: 23  RNRPYVCNICFKHFETPSKLARHYLIHTGQKPFECDVCHKTFRQLVHLERHQLTH--SLP 80
           +++ + C+   K F       RH   HTG+KPF+C  C K+F  L+HL +H+  H     
Sbjct: 150 QSKIFQCDKYVKVFHKLLNSNRHNTKHTGKKPFKCKKCGKSFCMLLHLCQHKRIHIRENS 209

Query: 81  FKCSICQRHFKNLKTFVKHQQLHNETYQNNVKQVRRLLEAKQEKSMYGVYNTFTTEERWA 140
           ++C  C + F    T  +H+++H                               T E+  
Sbjct: 210 YRCEECGKAFIWFSTLTRHRRVH-------------------------------TGEKSY 238

Query: 141 LHPCSKSDPMYS-MKRRKNIHA------CTICGKMFPSQSKLDRHVLIHTGQRPFKCVLC 193
            + C KS    S +   K IH       C  CG  F   S L RH LIHT ++P+KC   
Sbjct: 239 KYECGKSFNQDSNLTTHKRIHTGQKPYKCEECGTSFYQFSYLTRHKLIHTREKPYKCEQY 298

Query: 194 TKSFRQSTHLKIHQLTHSEERPFQCCFCQKGFKIQSKLLKHKQIHTRNKAFRALLLKKRR 253
            K+F QS+ L  H++ H+ E+P++C  C K F I S   KHK IHT  K+ R     K  
Sbjct: 299 GKTFNQSSTLTGHKIIHNGEKPYKCEECGKAFSIFSTPTKHKIIHTEEKSHRCEEYCKAY 358

Query: 254 TESRPLP--NKLNANQGGFENGEIGES-EENNPLDVHSIYIV---PFQCPKCEKCFESEQ 307
            ES  L    +++  +  ++  E G++    + L  H I        +C +C K ++   
Sbjct: 359 KESSHLTTHKRIHTGEKPYKCEECGKAFSIFSTLTKHKIIHTEEKSHRCEECGKAYKESS 418

Query: 308 ILNEHSCFAARSGKIPSRFK---RSYNYKTIVKKILAKLKRARSKKLDNFQSEKKVFKKS 364
            L  H      +G+ P + +   ++++  +I+ K   K+     K     +  K   + S
Sbjct: 419 HLTTHK--RIHTGEKPYKCEECGKTFSVFSILTK--HKIIHTEEKPYKCEECGKAFKRSS 474

Query: 365 FLRNCDLISGEQ---SSEQTQRTFVGSLGKHGTYKTIGNRKKKTLTLPFSWQNMGKNLK- 420
            L    +I  E+     E+  + F  S      +K I   +K     P+  +  GK  K 
Sbjct: 475 TLTKHRIIHTEEKPYKCEECGKAFNQS-STLSIHKIIHTGEK-----PYKCEECGKAFKR 528

Query: 421 -GILTTENILSIDNSVNKKDLSICGSSGEEFFNNCEVL---------------QCGFSVP 464
              LT   ++       K     C   G+ F  +  +                +CG S  
Sbjct: 529 SSTLTIHKMIHTGEKPYK-----CEECGKAFNRSSHLTTHKRIHTGHKPYKCKECGKSFS 583

Query: 465 RENIRTRHKIC-------PCDKCEKVFPSISKLKRHYLIHTGQRPFGCNICGKSFRQSAH 517
             +  T+HKI         C++C K F   S L  H  IHTG++P+ C  CGK+F++S+H
Sbjct: 584 VFSTLTKHKIIHTDKKPYKCEECGKAFNRSSILSIHKKIHTGEKPYKCEECGKAFKRSSH 643

Query: 518 LKRHEQTHNEKSPY-ASLCQVEFGNFNNLSNHSGNNVNYNASQQCQAPGVQKYEVSESDQ 576
           L  H+Q H+ + PY    C   F  F+ L+ H   +       +C+  G   Y  S  + 
Sbjct: 644 LAGHKQIHSVQKPYKCEECGKAFSIFSTLTKHKIIHTE-EKPYKCEKCGKTFYRFSNLNT 702

Query: 577 MSGVKAESQDFIPGSTGQ-PCLPNVLLESEQSNPFCSYSEHQEKNDVFLYRCSVCAKSFR 635
              +           TG+ PC                             +C  C K+F 
Sbjct: 703 HKII----------HTGEKPC-----------------------------KCEECGKAFN 723

Query: 636 SPSKLERHYLIHAGQKPFECSVCGKTFRQAPHWKRHQLTH 675
             S L +H LIH G KP++C  CGK FR++ H  RH++ H
Sbjct: 724 HSSNLIKHKLIHTGDKPYKCEACGKAFRRSSHLSRHKIIH 763



 Score =  172 bits (435), Expect = 1e-42
 Identities = 169/669 (25%), Positives = 264/669 (39%), Gaps = 160/669 (23%)

Query: 30  NICFKHFETPSKLARHYLIHTGQKPFECDVCHKTFRQLVHLERHQLTHS--LPFKCSICQ 87
           N C  H E  ++L   YL  T  K F+CD   K F +L++  RH   H+   PFKC  C 
Sbjct: 130 NECNVHKEGYNEL-NQYLTTTQSKIFQCDKYVKVFHKLLNSNRHNTKHTGKKPFKCKKCG 188

Query: 88  RHFKNLKTFVKHQQLHNETYQNNVKQVRRLLEAKQEKSMYGVYNTFTTEERWALHPCSKS 147
           + F  L                                               LH C   
Sbjct: 189 KSFCML-----------------------------------------------LHLCQHK 201

Query: 148 DPMYSMKRRKNIHACTICGKMFPSQSKLDRHVLIHTGQRPFKCVLCTKSFRQSTHLKIHQ 207
                +  R+N + C  CGK F   S L RH  +HTG++ +K   C KSF Q ++L  H+
Sbjct: 202 ----RIHIRENSYRCEECGKAFIWFSTLTRHRRVHTGEKSYKYE-CGKSFNQDSNLTTHK 256

Query: 208 LTHSEERPFQCCFCQKGFKIQSKLLKHKQIHTRNKAFRALLLKKRRTESRPLP-NKLNAN 266
             H+ ++P++C  C   F   S L +HK IHTR K ++     K   +S  L  +K+   
Sbjct: 257 RIHTGQKPYKCEECGTSFYQFSYLTRHKLIHTREKPYKCEQYGKTFNQSSTLTGHKI--- 313

Query: 267 QGGFENGEIGESEENNPLDVHSIYIVPFQCPKCEKCFESEQILNEHSCF-----AARSGK 321
                NGE                  P++C +C K F       +H        + R  +
Sbjct: 314 ---IHNGE-----------------KPYKCEECGKAFSIFSTPTKHKIIHTEEKSHRCEE 353

Query: 322 IPSRFKRSYNYKTIVKKILAKLKRARSKKLDNFQSEKKVFKKSFLRNCDLISGEQSSEQT 381
               +K S ++ T  K+I    K  + ++     S   +F  S L    +I  E+ S + 
Sbjct: 354 YCKAYKES-SHLTTHKRIHTGEKPYKCEECGKAFS---IF--STLTKHKIIHTEEKSHRC 407

Query: 382 QRTFVGSLGKHGTYKTIGNRKKKTLTLPFSWQNMGKNLK--GILTTENILSIDNSVNKKD 439
           +    G   K  ++ T  +++  T   P+  +  GK      ILT   I+  +    K  
Sbjct: 408 EEC--GKAYKESSHLTT-HKRIHTGEKPYKCEECGKTFSVFSILTKHKIIHTEEKPYK-- 462

Query: 440 LSICGSSGEEFFNNCEVLQCGFSVPRENIRTRHKIC-------PCDKCEKVFPSISKLKR 492
                         CE  +CG +  R +  T+H+I         C++C K F   S L  
Sbjct: 463 --------------CE--ECGKAFKRSSTLTKHRIIHTEEKPYKCEECGKAFNQSSTLSI 506

Query: 493 HYLIHTGQRPFGCNICGKSFRQSAHLKRHEQTHNEKSPYASLCQVEFGNFNNLSNHSGNN 552
           H +IHTG++P+ C  CGK+F++S+ L  H+  H  + PY   C+ E G   N S+H   +
Sbjct: 507 HKIIHTGEKPYKCEECGKAFKRSSTLTIHKMIHTGEKPYK--CE-ECGKAFNRSSHLTTH 563

Query: 553 VNYNASQQCQAPGVQKYEVSESDQMSGVKAESQDFIPGSTGQPCLPNVLLESEQSNPFCS 612
              +        G + Y+  E  +   V                             F +
Sbjct: 564 KRIHT-------GHKPYKCKECGKSFSV-----------------------------FST 587

Query: 613 YSEHQE-KNDVFLYRCSVCAKSFRSPSKLERHYLIHAGQKPFECSVCGKTFRQAPHWKRH 671
            ++H+    D   Y+C  C K+F   S L  H  IH G+KP++C  CGK F+++ H   H
Sbjct: 588 LTKHKIIHTDKKPYKCEECGKAFNRSSILSIHKKIHTGEKPYKCEECGKAFKRSSHLAGH 647

Query: 672 QLTHFKERP 680
           +  H  ++P
Sbjct: 648 KQIHSVQKP 656



 Score = 92.8 bits (229), Expect = 9e-19
 Identities = 61/220 (27%), Positives = 96/220 (43%), Gaps = 19/220 (8%)

Query: 479 KCEKVFPSISKLKRHYLIHTGQRPFGCNICGKSFRQSAHLKRHEQTHNEKSPYASLCQVE 538
           +C K F   S L  H  IHTGQ+P+ C  CG SF Q ++L RH+  H  + PY   C+  
Sbjct: 241 ECGKSFNQDSNLTTHKRIHTGQKPYKCEECGTSFYQFSYLTRHKLIHTREKPYK--CEQY 298

Query: 539 FGNFNNLSNHSGNNVNYNASQ--QCQAPGVQKYEVSESDQMSGVKAESQDFIPGSTGQPC 596
              FN  S  +G+ + +N  +  +C+  G      S   +   +  E +          C
Sbjct: 299 GKTFNQSSTLTGHKIIHNGEKPYKCEECGKAFSIFSTPTKHKIIHTEEKS-------HRC 351

Query: 597 LPNVLLESEQSNPFCSYSEHQEKNDVFLYRCSVCAKSFRSPSKLERHYLIHAGQKPFECS 656
                   E S+       H  +     Y+C  C K+F   S L +H +IH  +K   C 
Sbjct: 352 EEYCKAYKESSHLTTHKRIHTGEKP---YKCEECGKAFSIFSTLTKHKIIHTEEKSHRCE 408

Query: 657 VCGKTFRQAPHWKRHQLTHFKERPQ-----GKVVALDSVM 691
            CGK ++++ H   H+  H  E+P      GK  ++ S++
Sbjct: 409 ECGKAYKESSHLTTHKRIHTGEKPYKCEECGKTFSVFSIL 448



 Score = 91.3 bits (225), Expect = 3e-18
 Identities = 53/169 (31%), Positives = 81/169 (47%), Gaps = 11/169 (6%)

Query: 25  RPYVCNICFKHFETPSKLARHYLIHTGQKPFECDVCHKTFRQLVHLERHQLTHSL--PFK 82
           +PY C  C K F   S L+ H  IHTG+KP++C+ C K F++  HL  H+  HS+  P+K
Sbjct: 599 KPYKCEECGKAFNRSSILSIHKKIHTGEKPYKCEECGKAFKRSSHLAGHKQIHSVQKPYK 658

Query: 83  CSICQRHFKNLKTFVKHQQLHNETYQNNVKQVRRLLEAKQEKSMYGVYNTFTTEERWALH 142
           C  C + F    T  KH+ +H E      ++  +        + + + +T   E+     
Sbjct: 659 CEECGKAFSIFSTLTKHKIIHTEEKPYKCEKCGKTFYRFSNLNTHKIIHT--GEKPCKCE 716

Query: 143 PCSKS-DPMYSMKRRKNIHA------CTICGKMFPSQSKLDRHVLIHTG 184
            C K+ +   ++ + K IH       C  CGK F   S L RH +IH G
Sbjct: 717 ECGKAFNHSSNLIKHKLIHTGDKPYKCEACGKAFRRSSHLSRHKIIHIG 765



 Score = 33.1 bits (74), Expect = 0.88
 Identities = 13/28 (46%), Positives = 17/28 (60%)

Query: 24  NRPYVCNICFKHFETPSKLARHYLIHTG 51
           ++PY C  C K F   S L+RH +IH G
Sbjct: 738 DKPYKCEACGKAFRRSSHLSRHKIIHIG 765


>gi|211057416 zinc finger protein 841 [Homo sapiens]
          Length = 924

 Score =  206 bits (523), Expect = 8e-53
 Identities = 178/677 (26%), Positives = 270/677 (39%), Gaps = 108/677 (15%)

Query: 23  RNRPYVCNICFKHFETPSKLARHYLIHTGQKPFECDVCHKTFRQLVHLERHQLTHS--LP 80
           R +PY C++C + F   S L  H   HTG KP+ C+ C K+F +  HL  HQ  H+   P
Sbjct: 313 RGKPYQCDVCGRIFRQNSDLVNHRRSHTGDKPYICNECGKSFSKSSHLAVHQRIHTGEKP 372

Query: 81  FKCSICQRHFKNLKTFVKHQQLHNETYQNNVKQVRRLLEAKQEKSMYGVYNTFTTEERWA 140
           +KC+ C + F    +   HQ +H         +  +    K+  S+   +     ++ + 
Sbjct: 373 YKCNRCGKCFSQSSSLATHQTVHTGDKPYKCNECGKTF--KRNSSLTAHHIIHAGKKPYT 430

Query: 141 LHPCSKSDPMYSMKRRKNI-------HACTICGKMFPSQSKLDRHVLIHTGQRPFKCVLC 193
              C K     S   R  I       + C  CGK+F  +S+L  H  IHTG++P+KC  C
Sbjct: 431 CDVCGKVFYQNSQLVRHQIIHTGETPYKCNECGKVFFQRSRLAGHRRIHTGEKPYKCNEC 490

Query: 194 TKSFRQSTHLKIHQLTHSEERPFQCCFCQKGFKIQSKLLKHKQIHTRNKAFRALLLKKRR 253
            K F Q +HL +HQ  H+ E+P++C  C K F   S L  H++IHT  K ++  +  K  
Sbjct: 491 GKVFSQHSHLAVHQRVHTGEKPYKCNECGKAFNWGSLLTVHQRIHTGEKPYKCNVCGKV- 549

Query: 254 TESRPLPNKLNANQGGFENGEIGESEENNPLDVHSIYIVPFQCPKCEKCFESEQILNEHS 313
                       N GG+ +  +       PL           C KC   F     L  H 
Sbjct: 550 -----------FNYGGYLSVHMRCHTGEKPL----------HCNKCGMVFTYYSCLARHQ 588

Query: 314 CFAARSGKIPSRFKRSYNYKTIVKKILAKLKRARSKKLDNFQSEK--KVFK--KSFLRNC 369
                +G+ P  +K +   K  +      + R        FQ  +  KVF       R+ 
Sbjct: 589 --RMHTGEKP--YKCNVCGKVFIDSGNLSIHRRSHTGEKPFQCNECGKVFSYYSCLARHR 644

Query: 370 DLISGEQ-------SSEQTQRTFVGSLGKHGTYKTIGNRKKKTLTLPFSWQNMGKNLKGI 422
            + +GE+           TQR+   SL KH    T  N        P+     G+     
Sbjct: 645 KIHTGEKPYKCNDCGKAYTQRS---SLTKHLVIHTGEN--------PYHCNEFGE---AF 690

Query: 423 LTTENILSIDNSVNKKDLSICGSSGEEFFNNCEVLQCGFSVPRENIRTRHKICPCDKCEK 482
           + +  +     +   +    C   G  F +   +      V  +   T      C +C K
Sbjct: 691 IQSSKLARYHRNPTGEKPHKCSECGRTFSHKTSL------VYHQRRHTGEMPYKCIECGK 744

Query: 483 VFPSISKLKRHYLIHTGQRPFGCNICGKSFRQSAHLKRHEQTHNEKSPY-ASLCQVEFGN 541
           VF S + L RH  IHTG++P+ CN CGK FR  + L RH   H  + PY  + C   F  
Sbjct: 745 VFNSTTTLARHRRIHTGEKPYKCNECGKVFRYRSGLARHWSIHTGEKPYKCNECGKAFRV 804

Query: 542 FNNLSNHSGNNVNYNASQQCQAPGVQKYEVSESDQMSGVKAESQDFIPGSTGQPCLPNVL 601
            + L NH           Q    G + Y+ +E  +          FI             
Sbjct: 805 RSILLNH-----------QMMHTGEKPYKCNECGKA---------FI------------- 831

Query: 602 LESEQSNPFCSYSEHQEKNDVFLYRCSVCAKSFRSPSKLERHYLIHAGQKPFECSVCGKT 661
              E+SN       H  +     Y+C  C K+F   S L +H  IH+ +KP++C+ CGK+
Sbjct: 832 ---ERSNLVYHQRNHTGEKP---YKCMECGKAFGRRSCLTKHQRIHSSEKPYKCNECGKS 885

Query: 662 FRQAPHWKRHQLTHFKE 678
           +       +HQ+ H  E
Sbjct: 886 YISRSGLTKHQIKHAGE 902



 Score =  192 bits (488), Expect = 9e-49
 Identities = 168/678 (24%), Positives = 279/678 (41%), Gaps = 78/678 (11%)

Query: 23  RNRPYVCNICFKHFETPSKLARHYLIHTGQKPFECDVCHKTFRQLVHLERHQLTHSL--P 80
           R +PY+ N C K F   S L  H +IHT +KP+ C+   K F +   L  HQ+ H+   P
Sbjct: 257 REKPYIGNECGKAFRVSSSLINHQMIHTTEKPYRCNESGKAFHRGSLLTVHQIVHTRGKP 316

Query: 81  FKCSICQRHFKNLKTFVKHQQLHNETYQNNVKQVRRLLEAKQEKSMYGVYNTFTTEERWA 140
           ++C +C R F+     V H++ H         +  +        +++      T E+ + 
Sbjct: 317 YQCDVCGRIFRQNSDLVNHRRSHTGDKPYICNECGKSFSKSSHLAVH--QRIHTGEKPYK 374

Query: 141 LHPCSKS-DPMYSMKRRKNIHA------CTICGKMFPSQSKLDRHVLIHTGQRPFKCVLC 193
            + C K      S+   + +H       C  CGK F   S L  H +IH G++P+ C +C
Sbjct: 375 CNRCGKCFSQSSSLATHQTVHTGDKPYKCNECGKTFKRNSSLTAHHIIHAGKKPYTCDVC 434

Query: 194 TKSFRQSTHLKIHQLTHSEERPFQCCFCQKGFKIQSKLLKHKQIHTRNKAFRALLLKKRR 253
            K F Q++ L  HQ+ H+ E P++C  C K F  +S+L  H++IHT  K ++     K  
Sbjct: 435 GKVFYQNSQLVRHQIIHTGETPYKCNECGKVFFQRSRLAGHRRIHTGEKPYKCNECGKVF 494

Query: 254 TESRPLP--NKLNANQGGFENGEIGESEE-NNPLDVHSIYIV---PFQCPKCEKCFESEQ 307
           ++   L    +++  +  ++  E G++    + L VH        P++C  C K F    
Sbjct: 495 SQHSHLAVHQRVHTGEKPYKCNECGKAFNWGSLLTVHQRIHTGEKPYKCNVCGKVFNYGG 554

Query: 308 ILNEHSCFAARSGKIPSRFKRSYNYKTIVKKILAKLKRARSKKLDNFQSEKK--VFKKSF 365
            L+ H      +G+ P    +     T    +      AR +++   +   K  V  K F
Sbjct: 555 YLSVH--MRCHTGEKPLHCNKCGMVFTYYSCL------ARHQRMHTGEKPYKCNVCGKVF 606

Query: 366 LRNCDLISGEQSSEQTQRTFVGSLGKHGTYKTIGNRKKKTLT--LPFSWQNMGKNLKGIL 423
           + + +L    +S    +       GK  +Y +   R +K  T   P+   + GK      
Sbjct: 607 IDSGNLSIHRRSHTGEKPFQCNECGKVFSYYSCLARHRKIHTGEKPYKCNDCGKAYTQRS 666

Query: 424 TTENILSIDNSVNKKDLSICGSSGEEFFNNCEVLQCGFSVPRENIRTRHKICPCDKCEKV 483
           +    L I    N      C   GE F  + ++ +   +   E     HK   C +C + 
Sbjct: 667 SLTKHLVIHTGENPYH---CNEFGEAFIQSSKLARYHRNPTGEK---PHK---CSECGRT 717

Query: 484 FPSISKLKRHYLIHTGQRPFGCNICGKSFRQSAHLKRHEQTHNEKSPY-ASLCQVEFGNF 542
           F   + L  H   HTG+ P+ C  CGK F  +  L RH + H  + PY  + C   F   
Sbjct: 718 FSHKTSLVYHQRRHTGEMPYKCIECGKVFNSTTTLARHRRIHTGEKPYKCNECGKVFRYR 777

Query: 543 NNLSNHSGNNVNYNASQQCQAPGVQKYEVSESDQMSGVKAESQDFIPGSTGQPCLPNVLL 602
           + L+ H   +            G + Y+ +E  +   V++                 +LL
Sbjct: 778 SGLARHWSIHT-----------GEKPYKCNECGKAFRVRS-----------------ILL 809

Query: 603 ESEQSNPFCSYSEHQEKNDVFLYRCSVCAKSFRSPSKLERHYLIHAGQKPFECSVCGKTF 662
             +  +         EK     Y+C+ C K+F   S L  H   H G+KP++C  CGK F
Sbjct: 810 NHQMMHT-------GEKP----YKCNECGKAFIERSNLVYHQRNHTGEKPYKCMECGKAF 858

Query: 663 RQAPHWKRHQLTHFKERP 680
            +     +HQ  H  E+P
Sbjct: 859 GRRSCLTKHQRIHSSEKP 876



 Score =  166 bits (420), Expect = 7e-41
 Identities = 165/688 (23%), Positives = 273/688 (39%), Gaps = 100/688 (14%)

Query: 12  IQQCVVANKLPRNRPYV-CNICFKH---FETPSKLARHYLIHTGQKPFECDVCHKTFRQL 67
           +  C +A+ L R  P V  NI  K+   F   S   +    H  +KP+  + C K FR  
Sbjct: 214 VNNCFLASPLQRIFPGVQTNISRKYGNDFLQLSLPTQDEKTHIREKPYIGNECGKAFRVS 273

Query: 68  VHLERHQLTHSL--PFKCSICQRHFKNLKTFVKHQQLHNETYQNNVKQVRRLLEAKQEKS 125
             L  HQ+ H+   P++C+   + F        HQ +H                      
Sbjct: 274 SSLINHQMIHTTEKPYRCNESGKAFHRGSLLTVHQIVHT--------------------- 312

Query: 126 MYGVYNTFTTEERWALHPCSKSDPMYSMKRRKNIHACTICGKMFPSQSKLDRHVLIHTGQ 185
                                         R   + C +CG++F   S L  H   HTG 
Sbjct: 313 ------------------------------RGKPYQCDVCGRIFRQNSDLVNHRRSHTGD 342

Query: 186 RPFKCVLCTKSFRQSTHLKIHQLTHSEERPFQCCFCQKGFKIQSKLLKHKQIHTRNKAFR 245
           +P+ C  C KSF +S+HL +HQ  H+ E+P++C  C K F   S L  H+ +HT +K ++
Sbjct: 343 KPYICNECGKSFSKSSHLAVHQRIHTGEKPYKCNRCGKCFSQSSSLATHQTVHTGDKPYK 402

Query: 246 ALLLKK--RRTESRPLPNKLNANQGGFENGEIGES-EENNPLDVHSIYIV---PFQCPKC 299
                K  +R  S    + ++A +  +     G+   +N+ L  H I      P++C +C
Sbjct: 403 CNECGKTFKRNSSLTAHHIIHAGKKPYTCDVCGKVFYQNSQLVRHQIIHTGETPYKCNEC 462

Query: 300 EKCFESEQILNEHSCFAARSGKIPSRFKRSYNYKTIVKKILAKLKRARSKKLDNFQSEKK 359
            K F     L  H      +G+ P +        +    +    +    +K        K
Sbjct: 463 GKVFFQRSRLAGHR--RIHTGEKPYKCNECGKVFSQHSHLAVHQRVHTGEKPYKCNECGK 520

Query: 360 VFKKSFLRNCDLISGEQSSEQTQRTF----VGSLGKHGTYKTIGNRKKKTLTLPFSWQNM 415
            F         L++  Q     ++ +     G +  +G Y ++ + +  T   P      
Sbjct: 521 AFNWG-----SLLTVHQRIHTGEKPYKCNVCGKVFNYGGYLSV-HMRCHTGEKPLHCNKC 574

Query: 416 GKNLKGILTTENILSIDNSVNKKDLSI-CGSSGEEFFNNCEVLQCGFSVPRENIRTRHKI 474
           G     + T  + L+    ++  +    C   G+ F ++  +     S+ R +  T  K 
Sbjct: 575 GM----VFTYYSCLARHQRMHTGEKPYKCNVCGKVFIDSGNL-----SIHRRS-HTGEKP 624

Query: 475 CPCDKCEKVFPSISKLKRHYLIHTGQRPFGCNICGKSFRQSAHLKRHEQTHNEKSPYASL 534
             C++C KVF   S L RH  IHTG++P+ CN CGK++ Q + L +H   H  ++PY   
Sbjct: 625 FQCNECGKVFSYYSCLARHRKIHTGEKPYKCNDCGKAYTQRSSLTKHLVIHTGENPY--- 681

Query: 535 CQVEFGNFNNLSNHSGNNVNYNASQQCQAPGVQKYEVSESDQMSGVKAESQDFIPGSTGQ 594
                  F      S     Y+ +   + P    ++ SE  +    K          TG+
Sbjct: 682 ---HCNEFGEAFIQSSKLARYHRNPTGEKP----HKCSECGRTFSHKTSLVYHQRRHTGE 734

Query: 595 PCLPNVLLE-SEQSNPFCSYSEHQE-KNDVFLYRCSVCAKSFRSPSKLERHYLIHAGQKP 652
             +P   +E  +  N   + + H+        Y+C+ C K FR  S L RH+ IH G+KP
Sbjct: 735 --MPYKCIECGKVFNSTTTLARHRRIHTGEKPYKCNECGKVFRYRSGLARHWSIHTGEKP 792

Query: 653 FECSVCGKTFRQAPHWKRHQLTHFKERP 680
           ++C+ CGK FR       HQ+ H  E+P
Sbjct: 793 YKCNECGKAFRVRSILLNHQMMHTGEKP 820


>gi|47271464 zinc finger protein 607 [Homo sapiens]
          Length = 696

 Score =  206 bits (523), Expect = 8e-53
 Identities = 176/691 (25%), Positives = 288/691 (41%), Gaps = 97/691 (14%)

Query: 1   MMAENNLKMLKIQQCVVANKLPRN--RPYVCNICFKHFETPSKLARHYLIHTGQKPFECD 58
           ++++  +++ +   CV  ++   N  +PY C  C K F   ++L  H  IHT ++P +C+
Sbjct: 86  IISDGKMQLYRKHSCVTLHQRIHNGQKPYECKQCQKSFSHLTELMVHQTIHTSEEPDQCE 145

Query: 59  VCHKTFRQLVHLERHQLTHSL--PFKCSICQRHFKNLKTFVKHQQLHNETYQNNVKQVRR 116
              K F  L  L +HQ  ++   P++C  C + F       +H ++H          V +
Sbjct: 146 KFRKAFSHLTDLRKHQKINAREKPYECEECGKVFSYPANLAQHGKVH----------VEK 195

Query: 117 LLEAKQEKSMYGVYNTFTTEERWALHPCSKSDPMYSMKRRKNIHACTICGKMFPSQSKLD 176
             E K+    +      T   R+           Y  K     + C  CGK F    +L 
Sbjct: 196 PYECKECGEAFRTSRQLTVHHRFH----------YGEKP----YECKECGKAFSVYGRLS 241

Query: 177 RHVLIHTGQRPFKCVLCTKSFRQSTHLKIHQLTHSEERPFQCCFCQKGFKIQSKLLKHKQ 236
           RH  IHTG++PF+C  C KSFR    LK+HQ  H+ E+P +C  C K F+  S L+ HK+
Sbjct: 242 RHQSIHTGEKPFECNKCGKSFRLKAGLKVHQSIHTGEKPHECKECGKAFRQFSHLVGHKR 301

Query: 237 IHTRNKAFRALLLKKRRT--ESRPLPNKLNANQGGFENGEIGE--SEENNPLDVHSIYIV 292
           IHT  K +      K  T      +  ++ + +  +E  E GE  S  +     H+   V
Sbjct: 302 IHTGEKPYECKECGKGFTCRYQLTMHQRIYSGEKHYECKENGEAFSSGHQLTAPHTFESV 361

Query: 293 --PFQCPKCEKCFESEQILNEHSCFAARSGKIP---SRFKRSYNYKTIVKKILAKLKRAR 347
             P++C +C K F     L  H      SGK P   ++  +S+   + +           
Sbjct: 362 EKPYKCEECGKAFSVHGRLTRHQ--GIHSGKKPYECNKCGKSFRLNSSL----------- 408

Query: 348 SKKLDNFQSEKKVFKKSFLRNCDLISGEQSSEQTQRTFVGSLGKHGTYKTIGNRKKKTLT 407
            K   N  + +K +K    + C    G+  S++        +  H  YK           
Sbjct: 409 -KIHQNIHTGEKPYK---CKEC----GKAFSQRAHLAHHNRI--HTGYK----------- 447

Query: 408 LPFSWQNMGKNLKGILTTENILSIDNSVNKKDLS-ICGSSGEEFFNNCEVLQCGFSVPRE 466
            PF  +  GK+ +      + L I   ++  +   +C   G+ F  + ++          
Sbjct: 448 -PFECKECGKSFR----CASYLVIHERIHTGEKPYVCQECGKGFSYSHKL------TIHR 496

Query: 467 NIRTRHKICPCDKCEKVFPSISKLKRHYLIHTGQRPFGCNICGKSFRQSAHLKRHEQTHN 526
            + T  K   C +C K F    +L +H  IH+G+RPF CN CGKSFR  + LK H+  H+
Sbjct: 497 RVHTGEKPYECKECGKAFSVSGQLTQHLSIHSGKRPFECNKCGKSFRFISVLKAHQNIHS 556

Query: 527 EKSPY-ASLCQVEFGNFNNLSNHSGNNVNYNASQQCQAPGVQKYEVSESDQMSGVKAESQ 585
            + PY    C   F +  +L  H   +     S +C+  G      S       +    +
Sbjct: 557 AEKPYECKECGKAFRHATSLIYHDRTHAG-EKSYECKECGETFSHASHLIIHERIHTSDK 615

Query: 586 DFIPGSTGQPC-LPNVLLESEQSNPFCSYSEHQEKNDVFLYRCSVCAKSFRSPSKLERHY 644
            +     G+     + L+  E        S H + N    Y C  C K+F S  +L  H+
Sbjct: 616 PYECKRCGKAFHCASYLVRHE--------SVHADGNP---YMCEECGKAFNSSHELSIHH 664

Query: 645 LIHAGQKPFECSVCGKTFRQAPHWKRHQLTH 675
            +H G+KPF+C+ C ++FR     + HQ  H
Sbjct: 665 RVHTGEKPFKCNKCRRSFRLRSILEVHQRIH 695



 Score =  160 bits (405), Expect = 4e-39
 Identities = 151/615 (24%), Positives = 240/615 (39%), Gaps = 109/615 (17%)

Query: 73  HQLTHS--LPFKCSICQRHFKNLKTFVKHQQLHNETYQNNVKQVRRLLEAKQEKSMYGVY 130
           HQ  H+   P++C  CQ+ F +L   + HQ +H     +  ++ R+      +   +   
Sbjct: 104 HQRIHNGQKPYECKQCQKSFSHLTELMVHQTIHTSEEPDQCEKFRKAFSHLTDLRKHQKI 163

Query: 131 NTFTTEERWALHPCSKSDPMYSMKRRKNIHACTICGKMFPSQSKLDRHVLIHTGQRPFKC 190
           N                        R+  + C  CGK+F   + L +H  +H  ++P++C
Sbjct: 164 NA-----------------------REKPYECEECGKVFSYPANLAQHGKVHV-EKPYEC 199

Query: 191 VLCTKSFRQSTHLKIHQLTHSEERPFQCCFCQKGFKIQSKLLKHKQIHTRNKAFRALLLK 250
             C ++FR S  L +H   H  E+P++C  C K F +  +L +H+ IHT  K F      
Sbjct: 200 KECGEAFRTSRQLTVHHRFHYGEKPYECKECGKAFSVYGRLSRHQSIHTGEKPFECNKCG 259

Query: 251 KRRTESRPLPNKLNANQGGFENGEIGESEENNPLDVHSIYIVPFQCPKCEKCFESEQILN 310
           K          +L A     ++   GE               P +C +C K F     L 
Sbjct: 260 KSF--------RLKAGLKVHQSIHTGEK--------------PHECKECGKAFRQFSHLV 297

Query: 311 EHSCFAARSGKIPSRFKRSYNYKTIVKKILAKLKRARSKKLDNFQSEKKVFKKSFLRNCD 370
            H      +G+ P      Y  K   K    + +    +++  +  EK    K       
Sbjct: 298 GHK--RIHTGEKP------YECKECGKGFTCRYQLTMHQRI--YSGEKHYECKE------ 341

Query: 371 LISGEQSSEQTQRTFVGSLGKHGTYKTIGNRKKKTLTLPFSWQNMGK--NLKGILTTENI 428
             +GE  S   Q T       H T++++          P+  +  GK  ++ G LT    
Sbjct: 342 --NGEAFSSGHQLT-----APH-TFESVEK--------PYKCEECGKAFSVHGRLTRHQ- 384

Query: 429 LSIDNSVNKKDLSICGSSGEEFFNNCEVLQCGFSVPRENIRTRHKICPCDKCEKVFPSIS 488
             I +     + + CG S          L     +  +NI T  K   C +C K F   +
Sbjct: 385 -GIHSGKKPYECNKCGKSFR--------LNSSLKI-HQNIHTGEKPYKCKECGKAFSQRA 434

Query: 489 KLKRHYLIHTGQRPFGCNICGKSFRQSAHLKRHEQTHNEKSPYASL-CQVEFGNFNNLSN 547
            L  H  IHTG +PF C  CGKSFR +++L  HE+ H  + PY    C   F   + L+ 
Sbjct: 435 HLAHHNRIHTGYKPFECKECGKSFRCASYLVIHERIHTGEKPYVCQECGKGFSYSHKLTI 494

Query: 548 HSGNNVNYNASQQCQAPGVQKYEVSESDQMSGVKAESQDFIPGSTGQPCLPNVLLESEQS 607
           H   +            G + YE  E  +   V  +    +   +G+   P    +  +S
Sbjct: 495 HRRVHT-----------GEKPYECKECGKAFSVSGQLTQHLSIHSGKR--PFECNKCGKS 541

Query: 608 NPFCSYSE-HQEKNDVFL-YRCSVCAKSFRSPSKLERHYLIHAGQKPFECSVCGKTFRQA 665
             F S  + HQ  +     Y C  C K+FR  + L  H   HAG+K +EC  CG+TF  A
Sbjct: 542 FRFISVLKAHQNIHSAEKPYECKECGKAFRHATSLIYHDRTHAGEKSYECKECGETFSHA 601

Query: 666 PHWKRHQLTHFKERP 680
            H   H+  H  ++P
Sbjct: 602 SHLIIHERIHTSDKP 616



 Score = 42.4 bits (98), Expect = 0.001
 Identities = 21/59 (35%), Positives = 27/59 (45%), Gaps = 4/59 (6%)

Query: 626 RCSVCAKS----FRSPSKLERHYLIHAGQKPFECSVCGKTFRQAPHWKRHQLTHFKERP 680
           RC + +      +R  S +  H  IH GQKP+EC  C K+F        HQ  H  E P
Sbjct: 83  RCEIISDGKMQLYRKHSCVTLHQRIHNGQKPYECKQCQKSFSHLTELMVHQTIHTSEEP 141


>gi|222418585 zinc finger protein 814 [Homo sapiens]
          Length = 855

 Score =  203 bits (516), Expect = 5e-52
 Identities = 176/681 (25%), Positives = 273/681 (40%), Gaps = 86/681 (12%)

Query: 21  LPRNRPYVCNICFKHFETPSKLARHYLIHTGQKPFECDVCHKTFRQLVHLERHQLTHS-L 79
           L R   YVC  C K F   + L+ H  +HT +K  EC  C K+F + V    HQ  H+  
Sbjct: 236 LTREECYVCCECGKSFSKYASLSNHQRVHT-EKKHECGECGKSFSKYVSFSNHQRVHTEK 294

Query: 80  PFKCSICQRHFKNLKTFVKHQQLHNETYQNNVKQVRRLLEAKQEKSMYGVYNTFTTEERW 139
             +C  C + F    +F  HQ++H           +R  E  +    +  Y +F+  +R 
Sbjct: 295 KHECGECGKSFSKYVSFSNHQRVHTG---------KRPYECGECGKSFSKYASFSNHQR- 344

Query: 140 ALHPCSKSDPMYSMKRRKNIHACTICGKMFPSQSKLDRHVLIHTGQRPFKCVLCTKSFRQ 199
                        +   K  + C  CGK F        H  +HTG+RP++C  C KSF +
Sbjct: 345 -------------VHTEKKHYECGECGKSFSKYVSFSNHQRVHTGKRPYECGECGKSFSK 391

Query: 200 STHLKIHQLTHSEERPFQCCFCQKGFKIQSKLLKHKQIHTRNKAFRALLLKKRRTESRPL 259
                 HQ  H++++ ++C  C K F  +S L++H++ HT  K +      K  +    L
Sbjct: 392 YASFSNHQRVHTDKKHYECGECGKSFSQKSSLIQHQRFHTGEKPYGCEECGKSFSSEGHL 451

Query: 260 PN--KLNANQGGFENGEIGESEENNPLDVHSIYIV----PFQCPKCEKCFESEQILNEHS 313
            +  +++A +  F+ GE  +S  +    VH   +     P+QC +C K F  +  L  H 
Sbjct: 452 RSHQRVHAGERPFKCGECVKSFSHKRSLVHHQRVHSGERPYQCGECGKSFSQKGNLVLHQ 511

Query: 314 CFAARSGKIPSRFKRSYNYKTIVKKILAK--LKRARSKKLDNFQSEKKVFKKSFLRNCDL 371
                +G  P      Y      K   +K  L+  +     +   E     KSF     L
Sbjct: 512 --RVHTGARP------YECGECGKSFSSKGHLRNHQQIHTGDRLYECGECGKSFSHKGTL 563

Query: 372 ISGEQSSEQTQRTFVGSLGKHGTYKTIGN----RKKKTLTLPFSWQNMGKNL--KGILTT 425
           I  ++   + +    G  GK  ++ +IG+    ++  T   P+     GK+   K  L  
Sbjct: 564 ILHQRVHPRERSYGCGECGK--SFSSIGHLRSHQRVHTGERPYECGECGKSFSHKRSLVH 621

Query: 426 ENILSIDNSVNKKDLSICGSSGEEFFNNCEVLQCGFSVPRENIRTRHKICPCDKCEKVFP 485
              +       K     CG  G+ F         G     + + T  +   C +C K F 
Sbjct: 622 HQRMHTGERPYK-----CGDCGKSFNEK------GHLRNHQRVHTTERPFKCGECGKCFS 670

Query: 486 SISKLKRHYLIHTGQRPFGCNICGKSFRQSAHLKRHEQTHNEKSPYA-SLCQVEFGNFNN 544
               L  H   HTG+RP+ C  CGK F++ +HL  H++ HN + PYA   CQ  F N   
Sbjct: 671 HKGNLILHQHGHTGERPYVCRECGKLFKKKSHLLVHQRIHNGEKPYACEACQKFFRNKYQ 730

Query: 545 LSNHSGNNVNYNASQQCQAPGVQKYEVSESDQM---SGVKAESQDFIPGSTGQPCLPNVL 601
           L  H           Q    G + YE ++  +    S      +    G     C     
Sbjct: 731 LIAH-----------QRVHTGERPYECNDCGKSFTHSSTFCVHKRIHTGEKPYEC----- 774

Query: 602 LESEQSNPFCSYSEHQEKNDVFL----YRCSVCAKSFRSPSKLERHYLIHAGQKPFECSV 657
             SE    F   S   +   V      Y CS C KSF   S L +H  +H G+KP++C  
Sbjct: 775 --SECGKSFAESSSFTKHKRVHTGEKPYECSECGKSFAESSSLTKHKRVHTGEKPYKCEK 832

Query: 658 CGKTFRQAPHWKRHQLTHFKE 678
           CGK F +  H   HQ +H+++
Sbjct: 833 CGKLFNKKSHLLVHQSSHWRK 853



 Score =  150 bits (380), Expect = 3e-36
 Identities = 158/718 (22%), Positives = 272/718 (37%), Gaps = 124/718 (17%)

Query: 52  QKPFECDVCHKTFRQLVHLERHQLTHSLP--FKCSICQRHFKNLKTFVKHQQLH--NETY 107
           +K   C++C      ++H+  HQ TH      +C        +   F +HQ  H   + Y
Sbjct: 89  KKAHPCEMCGPILGDILHVADHQGTHHKQKLHRCEAWGNKLYDSGNFHQHQNEHIGEKPY 148

Query: 108 QNNVKQVRRLLEAK-------------------------QEKSMYGVYNTFTTE------ 136
           + +V++       K                         QE S  G  +   TE      
Sbjct: 149 RGSVEEALFAKRCKLHVSGESSVFSESGKDFLPRSGLLQQEASHTGEKSNSKTECVSPIQ 208

Query: 137 ERWALHPCSKSDPMYSMKR----------RKNIHACTICGKMFPSQSKLDRHVLIHT--- 183
              A + C +S   +S K           R+  + C  CGK F   + L  H  +HT   
Sbjct: 209 CGGAHYSCGESMKHFSTKHILSQHQRLLTREECYVCCECGKSFSKYASLSNHQRVHTEKK 268

Query: 184 -----------------------GQRPFKCVLCTKSFRQSTHLKIHQLTHSEERPFQCCF 220
                                   ++  +C  C KSF +      HQ  H+ +RP++C  
Sbjct: 269 HECGECGKSFSKYVSFSNHQRVHTEKKHECGECGKSFSKYVSFSNHQRVHTGKRPYECGE 328

Query: 221 CQKGFKIQSKLLKHKQIHTRNKAFRALLLKKRRTESRPLPN--KLNANQGGFENGEIGES 278
           C K F   +    H+++HT  K +      K  ++     N  +++  +  +E GE G+S
Sbjct: 329 CGKSFSKYASFSNHQRVHTEKKHYECGECGKSFSKYVSFSNHQRVHTGKRPYECGECGKS 388

Query: 279 -----EENNPLDVHSIYIVPFQCPKCEKCFESEQILNEHSCFAARSGKIPSRFKRSYNYK 333
                  +N   VH+     ++C +C K F  +  L +H  F   +G+ P      Y  +
Sbjct: 389 FSKYASFSNHQRVHTDK-KHYECGECGKSFSQKSSLIQHQRF--HTGEKP------YGCE 439

Query: 334 TIVKKILAKLKRARSKKLDNFQSEKKVFK-----KSFLRNCDLISGEQSSEQTQRTFVGS 388
              K   ++      +      + ++ FK     KSF     L+  ++     +    G 
Sbjct: 440 ECGKSFSSE---GHLRSHQRVHAGERPFKCGECVKSFSHKRSLVHHQRVHSGERPYQCGE 496

Query: 389 LGKHGTYK--TIGNRKKKTLTLPFSWQNMGKNLKGILTTENILSIDNSVNKKD-LSICGS 445
            GK  + K   + +++  T   P+     GK+     +++  L     ++  D L  CG 
Sbjct: 497 CGKSFSQKGNLVLHQRVHTGARPYECGECGKS----FSSKGHLRNHQQIHTGDRLYECGE 552

Query: 446 SGEEFFNNCEVLQCGFSVPRENIRTRHKICPCDKCEKVFPSISKLKRHYLIHTGQRPFGC 505
            G+ F +       G  +  + +  R +   C +C K F SI  L+ H  +HTG+RP+ C
Sbjct: 553 CGKSFSHK------GTLILHQRVHPRERSYGCGECGKSFSSIGHLRSHQRVHTGERPYEC 606

Query: 506 NICGKSFRQSAHLKRHEQTHNEKSPYASLCQVEFGNFNNLSNHSGNNVNYNASQQCQAPG 565
             CGKSF     L  H++ H  + PY      + G+     N  G+  N+      + P 
Sbjct: 607 GECGKSFSHKRSLVHHQRMHTGERPY------KCGDCGKSFNEKGHLRNHQRVHTTERP- 659

Query: 566 VQKYEVSESDQMSGVKAESQDFIPGSTGQ---PCLPNVLLESEQSNPFCSYSEHQEKNDV 622
              ++  E  +    K        G TG+    C     L  ++S+       H  +   
Sbjct: 660 ---FKCGECGKCFSHKGNLILHQHGHTGERPYVCRECGKLFKKKSHLLVHQRIHNGEKP- 715

Query: 623 FLYRCSVCAKSFRSPSKLERHYLIHAGQKPFECSVCGKTFRQAPHWKRHQLTHFKERP 680
             Y C  C K FR+  +L  H  +H G++P+EC+ CGK+F  +  +  H+  H  E+P
Sbjct: 716 --YACEACQKFFRNKYQLIAHQRVHTGERPYECNDCGKSFTHSSTFCVHKRIHTGEKP 771



 Score = 94.0 bits (232), Expect = 4e-19
 Identities = 62/241 (25%), Positives = 95/241 (39%), Gaps = 20/241 (8%)

Query: 443 CGSSGEEFFNNCEVLQCGFSVPRENIRTRHKICPCDKCEKVFPSISKLKRHYLIHTGQRP 502
           CG S + F     + Q       + + TR +   C +C K F   + L  H  +HT ++ 
Sbjct: 216 CGESMKHFSTKHILSQ------HQRLLTREECYVCCECGKSFSKYASLSNHQRVHT-EKK 268

Query: 503 FGCNICGKSFRQSAHLKRHEQTHNEKSPYASLCQVEFGNFNNLSNHSGNNVNYNASQQCQ 562
             C  CGKSF +      H++ H EK      C   F  + + SNH   +       +C 
Sbjct: 269 HECGECGKSFSKYVSFSNHQRVHTEKKHECGECGKSFSKYVSFSNHQRVHTG-KRPYECG 327

Query: 563 APGVQKYEVSESDQMSGVKAESQDFIPGSTGQPCLPNVLLESEQSNPFCSYSEHQEKNDV 622
             G    + +       V  E + +  G  G+             + + S+S HQ  +  
Sbjct: 328 ECGKSFSKYASFSNHQRVHTEKKHYECGECGK-----------SFSKYVSFSNHQRVHTG 376

Query: 623 FL-YRCSVCAKSFRSPSKLERHYLIHAGQKPFECSVCGKTFRQAPHWKRHQLTHFKERPQ 681
              Y C  C KSF   +    H  +H  +K +EC  CGK+F Q     +HQ  H  E+P 
Sbjct: 377 KRPYECGECGKSFSKYASFSNHQRVHTDKKHYECGECGKSFSQKSSLIQHQRFHTGEKPY 436

Query: 682 G 682
           G
Sbjct: 437 G 437


>gi|62243640 zinc finger protein 107 [Homo sapiens]
          Length = 783

 Score =  202 bits (515), Expect = 6e-52
 Identities = 186/707 (26%), Positives = 297/707 (42%), Gaps = 108/707 (15%)

Query: 23  RNRPYVCNICFKHFETPSKLARHYLIHTGQKPFECDVCHKTFRQLVHLERHQLTHS--LP 80
           R   Y C  C K F   S L +H  IHTG+KP++C+ C K F Q   L RH++ H+   P
Sbjct: 128 RVNSYKCEECGKAFNWFSTLTKHKRIHTGEKPYKCEECGKAFNQSSQLTRHKIIHTEEKP 187

Query: 81  FKCSICQRHFKNLKTFVKHQQLHNETYQNNVKQVRRLLEAKQEKSMYGVYNTFTTEERWA 140
            KC  C + FK       H+ +H        ++  ++       +   + +T   E  + 
Sbjct: 188 NKCEECGKAFKQASHLTIHKIIHTGEKPYKYEECGKVFSQSSHLTTQKILHT--GENLYK 245

Query: 141 LHPCSKSDPMYS-MKRRKNIHA------CTICGKMFPSQSKLDRHVLIHTGQRPFKCVLC 193
              C K+  ++S +   K IHA      C  CG+ F   S L++   IHTG +  KC  C
Sbjct: 246 CKECGKAFNLFSNLTNHKRIHAGEKPYKCKECGRAFNISSNLNKQEKIHTGGKLNKCEEC 305

Query: 194 TKSFRQSTHLKIHQLTHSEERPFQCCFCQKGFKIQSKLLKHKQIHTRNKAFRALLLKKRR 253
            K+F +S  L  H+    EE+P++C  C K F   S L +HK IHT  K ++     K  
Sbjct: 306 DKAFNRSLKLTAHKKILMEEKPYKCEECGKVFNQFSTLTRHKIIHTGEKPYKCKECGKAF 365

Query: 254 TESRPLPN--KLNANQGGFENGEIGES--EENNPLDVHSIYI--VPFQCPKCEKCFESEQ 307
            +S  L    K++  +  ++  E G++  + +N ++   IY    P++C +C K F    
Sbjct: 366 NQSSNLTEHKKIHTAEKSYKCEECGKAFNQHSNLINHRKIYSGEKPYKCEECGKAFNRSS 425

Query: 308 ILNEHSCFAARSGKIPSR-------FKRSYNYKTIVKKI--------------------- 339
            L  H      +G+ P +       F +S N  T  KKI                     
Sbjct: 426 TLTRHK--KIHTGEKPYKCEECDRAFSQSSNL-TEHKKIHTGEKPYKCEECGKAFNRFST 482

Query: 340 LAKLKRARS-KKLDNFQSEKKVFKKSF-LRNCDLISGEQSSEQTQRTFVGSLGKHGTYKT 397
           L K KR  + +K    +   K F +S+ L    ++  ++   + +    G   K  +++T
Sbjct: 483 LTKHKRIHTGEKPYKCEECGKAFNQSYQLTRHKIVHTKEKLNKCEE--FGKAFKQSSHRT 540

Query: 398 IGNRKKKTLTLPFSWQNMGK--NLKGILTTENILSIDNSVNKKDLSICGSSGEEF--FNN 453
           I ++   T   P+  +  GK  N    LTT+ I+    ++ K +       G+ F  F+N
Sbjct: 541 I-HKIIHTGEKPYKCEEHGKVFNQSSNLTTQKIIHTGENLYKFE-----EHGKAFNLFSN 594

Query: 454 CEVLQCGFSVPRENIRTRHKICPCDKCEKVFPSISKLKRHYLIHTGQRPFGCNICGKSFR 513
                       + I T  K   C++C K +   S L  H  IHTG++P+ C  CGK+F 
Sbjct: 595 I--------TNHKIIYTGEKPHKCEECGKAYNRFSNLTIHKRIHTGEKPYQCAECGKAFN 646

Query: 514 QSAHLKRHEQTHNEKSPYASLCQVEFGNFNNLSNHSGNNVNYNASQQCQAPGVQKYEVSE 573
            S+ L RH+  H  + PY   C+ E G   NLS+         A ++    G + Y+  E
Sbjct: 647 CSSTLNRHKIIHTGEKPYK--CK-ECGKAFNLSS------TLTAHKKIHT-GEKPYKCEE 696

Query: 574 SDQMSGVKAESQDFIPGSTGQPCLPNVLLESEQSNPFCSYSEHQEKNDVFLYRCSVCAKS 633
             +                           ++ SN       H  +     Y+C  C KS
Sbjct: 697 CGKAF-------------------------NQSSNLTTHKKIHTSEKP---YKCEECGKS 728

Query: 634 FRSPSKLERHYLIHAGQKPFECSVCGKTFRQAPHWKRHQLTHFKERP 680
           F   S L  H +IH G+KP++C   G+ F  + +   H+  H  E+P
Sbjct: 729 FNQFSSLNIHKIIHTGEKPYKCGDYGRAFNLSSNLTTHKKIHTGEKP 775



 Score =  200 bits (509), Expect = 3e-51
 Identities = 175/710 (24%), Positives = 277/710 (39%), Gaps = 124/710 (17%)

Query: 12  IQQCVVANKLPRNRPYVCNICFKHFETPSKLARHYLIHTGQKPFECDVCHKTFRQLVHLE 71
           + QC+ A     ++ + CN   K F+  S   R+   HTG K F+C  C K+F  L  L 
Sbjct: 64  VNQCLTATP---SKIFQCNKYVKVFDKFSNSNRYKRRHTGNKHFKCKECSKSFCVLSQLT 120

Query: 72  RHQLTHSL--PFKCSICQRHFKNLKTFVKHQQLHNETYQNNVKQVRRLLEAKQEKSMYGV 129
           +H+  H+    +KC  C + F    T  KH+++H                          
Sbjct: 121 QHRRIHTRVNSYKCEECGKAFNWFSTLTKHKRIH-------------------------- 154

Query: 130 YNTFTTEERWALHPCSKSDPMYS-MKRRKNIHA------CTICGKMFPSQSKLDRHVLIH 182
               T E+ +    C K+    S + R K IH       C  CGK F   S L  H +IH
Sbjct: 155 ----TGEKPYKCEECGKAFNQSSQLTRHKIIHTEEKPNKCEECGKAFKQASHLTIHKIIH 210

Query: 183 TGQRPFKCVLCTKSFRQSTHLKIHQLTHSEERPFQCCFCQKGFKIQSKLLKHKQIHTRNK 242
           TG++P+K   C K F QS+HL   ++ H+ E  ++C  C K F + S L  HK+IH   K
Sbjct: 211 TGEKPYKYEECGKVFSQSSHLTTQKILHTGENLYKCKECGKAFNLFSNLTNHKRIHAGEK 270

Query: 243 AFRALLLKKRRTESRPLPNKLNANQGGFENGEIGESEENNPLDVHSIYIV---------- 292
            ++     K    +  + + LN  +     G++ + EE +     S+ +           
Sbjct: 271 PYKC----KECGRAFNISSNLNKQEKIHTGGKLNKCEECDKAFNRSLKLTAHKKILMEEK 326

Query: 293 PFQCPKCEKCFESEQILNEHSCFAARSGKIPSRFKRSYNYKTIVKKILAKLKRARSKKLD 352
           P++C +C K F     L  H        KI    ++ Y  K   K           KK+ 
Sbjct: 327 PYKCEECGKVFNQFSTLTRH--------KIIHTGEKPYKCKECGKAFNQSSNLTEHKKIH 378

Query: 353 NFQSEKKVFK--KSFLRNCDLISGEQSSEQTQRTFVGSLGKHGTYKTIGNRKKKTLTLPF 410
             +   K  +  K+F ++ +LI+                          +RK  +   P+
Sbjct: 379 TAEKSYKCEECGKAFNQHSNLIN--------------------------HRKIYSGEKPY 412

Query: 411 SWQNMGKNLKGILTTENILSIDNSVNKKDLSICGSSGEEFFNNCEVLQCGFSVPRENIRT 470
             +  GK      T      I           C  +  +  N  E          + I T
Sbjct: 413 KCEECGKAFNRSSTLTRHKKIHTGEKPYKCEECDRAFSQSSNLTE---------HKKIHT 463

Query: 471 RHKICPCDKCEKVFPSISKLKRHYLIHTGQRPFGCNICGKSFRQSAHLKRHEQTHNEKSP 530
             K   C++C K F   S L +H  IHTG++P+ C  CGK+F QS  L RH+  H ++  
Sbjct: 464 GEKPYKCEECGKAFNRFSTLTKHKRIHTGEKPYKCEECGKAFNQSYQLTRHKIVHTKEK- 522

Query: 531 YASLCQVEFGNFNNLSNHSGNNVNYNASQQCQAPGVQKYEVSESDQMSGVKAESQDFIPG 590
             + C+ EFG     S+H           +    G + Y+  E  ++    +        
Sbjct: 523 -LNKCE-EFGKAFKQSSH-------RTIHKIIHTGEKPYKCEEHGKVFNQSSNLTTQKII 573

Query: 591 STGQPCLPNVLLESEQSNPFCSYSEHQEKNDVFL----YRCSVCAKSFRSPSKLERHYLI 646
            TG+    N+    E    F  +S       ++     ++C  C K++   S L  H  I
Sbjct: 574 HTGE----NLYKFEEHGKAFNLFSNITNHKIIYTGEKPHKCEECGKAYNRFSNLTIHKRI 629

Query: 647 HAGQKPFECSVCGKTFRQAPHWKRHQLTHFKERPQ-----GKVVALDSVM 691
           H G+KP++C+ CGK F  +    RH++ H  E+P      GK   L S +
Sbjct: 630 HTGEKPYQCAECGKAFNCSSTLNRHKIIHTGEKPYKCKECGKAFNLSSTL 679



 Score =  197 bits (501), Expect = 3e-50
 Identities = 176/696 (25%), Positives = 286/696 (41%), Gaps = 129/696 (18%)

Query: 25  RPYVCNICFKHFETPSKLARHYLIHTGQKPFECDVCHKTFRQLVHLERHQLTHS--LPFK 82
           +PY C  C K F   S+L RH +IHT +KP +C+ C K F+Q  HL  H++ H+   P+K
Sbjct: 158 KPYKCEECGKAFNQSSQLTRHKIIHTEEKPNKCEECGKAFKQASHLTIHKIIHTGEKPYK 217

Query: 83  CSICQRHFKNLKTFVKHQQLH-------------------NETYQNNVKQVRRLLEAKQE 123
              C + F         + LH                   N T    +    +  + K+ 
Sbjct: 218 YEECGKVFSQSSHLTTQKILHTGENLYKCKECGKAFNLFSNLTNHKRIHAGEKPYKCKEC 277

Query: 124 KSMYGVYNTFTTEER----WALHPCSKSDPMYSMKRRKNIHA----------CTICGKMF 169
              + + +    +E+      L+ C + D  ++   +   H           C  CGK+F
Sbjct: 278 GRAFNISSNLNKQEKIHTGGKLNKCEECDKAFNRSLKLTAHKKILMEEKPYKCEECGKVF 337

Query: 170 PSQSKLDRHVLIHTGQRPFKCVLCTKSFRQSTHLKIHQLTHSEERPFQCCFCQKGFKIQS 229
              S L RH +IHTG++P+KC  C K+F QS++L  H+  H+ E+ ++C  C K F   S
Sbjct: 338 NQFSTLTRHKIIHTGEKPYKCKECGKAFNQSSNLTEHKKIHTAEKSYKCEECGKAFNQHS 397

Query: 230 KLLKHKQIHTRNKAFRALLLKKRRTESRPLPN--KLNANQGGFENGEIGE--SEENNPLD 285
            L+ H++I++  K ++     K    S  L    K++  +  ++  E     S+ +N  +
Sbjct: 398 NLINHRKIYSGEKPYKCEECGKAFNRSSTLTRHKKIHTGEKPYKCEECDRAFSQSSNLTE 457

Query: 286 VHSIYI--VPFQCPKCEKCFESEQILNEHSCFAARSGKIPSR-------FKRSYNYKTIV 336
              I+    P++C +C K F     L +H      +G+ P +       F +SY      
Sbjct: 458 HKKIHTGEKPYKCEECGKAFNRFSTLTKHK--RIHTGEKPYKCEECGKAFNQSYQ----- 510

Query: 337 KKILAKLKRARSK-KLDNFQSEKKVFKKSFLRNCDLI--SGEQSSEQTQRTFVGSLGKHG 393
              L + K   +K KL+  +   K FK+S  R    I  +GE+  +  +   V +   + 
Sbjct: 511 ---LTRHKIVHTKEKLNKCEEFGKAFKQSSHRTIHKIIHTGEKPYKCEEHGKVFNQSSNL 567

Query: 394 TYKTIGNRKKKTLTLPFSWQNMGK--NLKGILTTENILSIDNSVNKKDLSICGSSGEEFF 451
           T + I +  +      + ++  GK  NL   +T   I+      +K +   CG +   F 
Sbjct: 568 TTQKIIHTGENL----YKFEEHGKAFNLFSNITNHKIIYTGEKPHKCEE--CGKAYNRFS 621

Query: 452 NNCEVLQCGFSVPRENIRTRHKICPCDKCEKVFPSISKLKRHYLIHTGQRPFGCNICGKS 511
           N             + I T  K   C +C K F   S L RH +IHTG++P+ C  CGK+
Sbjct: 622 N---------LTIHKRIHTGEKPYQCAECGKAFNCSSTLNRHKIIHTGEKPYKCKECGKA 672

Query: 512 FRQSAHLKRHEQTHNEKSPY-ASLCQVEFGNFNNLSNHSGNNVNYNASQQCQAPGVQKYE 570
           F  S+ L  H++ H  + PY    C   F   +NL+ H                  +K  
Sbjct: 673 FNLSSTLTAHKKIHTGEKPYKCEECGKAFNQSSNLTTH------------------KKIH 714

Query: 571 VSESDQMSGVKAESQDFIPGSTGQPCLPNVLLESEQSNPFCSYSEHQ-----EKNDVFLY 625
            SE                    + C        +  N F S + H+     EK     Y
Sbjct: 715 TSEKPYKC---------------EEC-------GKSFNQFSSLNIHKIIHTGEKP----Y 748

Query: 626 RCSVCAKSFRSPSKLERHYLIHAGQKPFECSVCGKT 661
           +C    ++F   S L  H  IH G+KP++C   GKT
Sbjct: 749 KCGDYGRAFNLSSNLTTHKKIHTGEKPYKCEY-GKT 783


>gi|7706775 zinc finger protein 107 [Homo sapiens]
          Length = 783

 Score =  202 bits (515), Expect = 6e-52
 Identities = 186/707 (26%), Positives = 297/707 (42%), Gaps = 108/707 (15%)

Query: 23  RNRPYVCNICFKHFETPSKLARHYLIHTGQKPFECDVCHKTFRQLVHLERHQLTHS--LP 80
           R   Y C  C K F   S L +H  IHTG+KP++C+ C K F Q   L RH++ H+   P
Sbjct: 128 RVNSYKCEECGKAFNWFSTLTKHKRIHTGEKPYKCEECGKAFNQSSQLTRHKIIHTEEKP 187

Query: 81  FKCSICQRHFKNLKTFVKHQQLHNETYQNNVKQVRRLLEAKQEKSMYGVYNTFTTEERWA 140
            KC  C + FK       H+ +H        ++  ++       +   + +T   E  + 
Sbjct: 188 NKCEECGKAFKQASHLTIHKIIHTGEKPYKYEECGKVFSQSSHLTTQKILHT--GENLYK 245

Query: 141 LHPCSKSDPMYS-MKRRKNIHA------CTICGKMFPSQSKLDRHVLIHTGQRPFKCVLC 193
              C K+  ++S +   K IHA      C  CG+ F   S L++   IHTG +  KC  C
Sbjct: 246 CKECGKAFNLFSNLTNHKRIHAGEKPYKCKECGRAFNISSNLNKQEKIHTGGKLNKCEEC 305

Query: 194 TKSFRQSTHLKIHQLTHSEERPFQCCFCQKGFKIQSKLLKHKQIHTRNKAFRALLLKKRR 253
            K+F +S  L  H+    EE+P++C  C K F   S L +HK IHT  K ++     K  
Sbjct: 306 DKAFNRSLKLTAHKKILMEEKPYKCEECGKVFNQFSTLTRHKIIHTGEKPYKCKECGKAF 365

Query: 254 TESRPLPN--KLNANQGGFENGEIGES--EENNPLDVHSIYI--VPFQCPKCEKCFESEQ 307
            +S  L    K++  +  ++  E G++  + +N ++   IY    P++C +C K F    
Sbjct: 366 NQSSNLTEHKKIHTAEKSYKCEECGKAFNQHSNLINHRKIYSGEKPYKCEECGKAFNRSS 425

Query: 308 ILNEHSCFAARSGKIPSR-------FKRSYNYKTIVKKI--------------------- 339
            L  H      +G+ P +       F +S N  T  KKI                     
Sbjct: 426 TLTRHK--KIHTGEKPYKCEECDRAFSQSSNL-TEHKKIHTGEKPYKCEECGKAFNRFST 482

Query: 340 LAKLKRARS-KKLDNFQSEKKVFKKSF-LRNCDLISGEQSSEQTQRTFVGSLGKHGTYKT 397
           L K KR  + +K    +   K F +S+ L    ++  ++   + +    G   K  +++T
Sbjct: 483 LTKHKRIHTGEKPYKCEECGKAFNQSYQLTRHKIVHTKEKLNKCEE--FGKAFKQSSHRT 540

Query: 398 IGNRKKKTLTLPFSWQNMGK--NLKGILTTENILSIDNSVNKKDLSICGSSGEEF--FNN 453
           I ++   T   P+  +  GK  N    LTT+ I+    ++ K +       G+ F  F+N
Sbjct: 541 I-HKIIHTGEKPYKCEEHGKVFNQSSNLTTQKIIHTGENLYKFE-----EHGKAFNLFSN 594

Query: 454 CEVLQCGFSVPRENIRTRHKICPCDKCEKVFPSISKLKRHYLIHTGQRPFGCNICGKSFR 513
                       + I T  K   C++C K +   S L  H  IHTG++P+ C  CGK+F 
Sbjct: 595 I--------TNHKIIYTGEKPHKCEECGKAYNRFSNLTIHKRIHTGEKPYQCAECGKAFN 646

Query: 514 QSAHLKRHEQTHNEKSPYASLCQVEFGNFNNLSNHSGNNVNYNASQQCQAPGVQKYEVSE 573
            S+ L RH+  H  + PY   C+ E G   NLS+         A ++    G + Y+  E
Sbjct: 647 CSSTLNRHKIIHTGEKPYK--CK-ECGKAFNLSS------TLTAHKKIHT-GEKPYKCEE 696

Query: 574 SDQMSGVKAESQDFIPGSTGQPCLPNVLLESEQSNPFCSYSEHQEKNDVFLYRCSVCAKS 633
             +                           ++ SN       H  +     Y+C  C KS
Sbjct: 697 CGKAF-------------------------NQSSNLTTHKKIHTSEKP---YKCEECGKS 728

Query: 634 FRSPSKLERHYLIHAGQKPFECSVCGKTFRQAPHWKRHQLTHFKERP 680
           F   S L  H +IH G+KP++C   G+ F  + +   H+  H  E+P
Sbjct: 729 FNQFSSLNIHKIIHTGEKPYKCGDYGRAFNLSSNLTTHKKIHTGEKP 775



 Score =  200 bits (509), Expect = 3e-51
 Identities = 175/710 (24%), Positives = 277/710 (39%), Gaps = 124/710 (17%)

Query: 12  IQQCVVANKLPRNRPYVCNICFKHFETPSKLARHYLIHTGQKPFECDVCHKTFRQLVHLE 71
           + QC+ A     ++ + CN   K F+  S   R+   HTG K F+C  C K+F  L  L 
Sbjct: 64  VNQCLTATP---SKIFQCNKYVKVFDKFSNSNRYKRRHTGNKHFKCKECSKSFCVLSQLT 120

Query: 72  RHQLTHSL--PFKCSICQRHFKNLKTFVKHQQLHNETYQNNVKQVRRLLEAKQEKSMYGV 129
           +H+  H+    +KC  C + F    T  KH+++H                          
Sbjct: 121 QHRRIHTRVNSYKCEECGKAFNWFSTLTKHKRIH-------------------------- 154

Query: 130 YNTFTTEERWALHPCSKSDPMYS-MKRRKNIHA------CTICGKMFPSQSKLDRHVLIH 182
               T E+ +    C K+    S + R K IH       C  CGK F   S L  H +IH
Sbjct: 155 ----TGEKPYKCEECGKAFNQSSQLTRHKIIHTEEKPNKCEECGKAFKQASHLTIHKIIH 210

Query: 183 TGQRPFKCVLCTKSFRQSTHLKIHQLTHSEERPFQCCFCQKGFKIQSKLLKHKQIHTRNK 242
           TG++P+K   C K F QS+HL   ++ H+ E  ++C  C K F + S L  HK+IH   K
Sbjct: 211 TGEKPYKYEECGKVFSQSSHLTTQKILHTGENLYKCKECGKAFNLFSNLTNHKRIHAGEK 270

Query: 243 AFRALLLKKRRTESRPLPNKLNANQGGFENGEIGESEENNPLDVHSIYIV---------- 292
            ++     K    +  + + LN  +     G++ + EE +     S+ +           
Sbjct: 271 PYKC----KECGRAFNISSNLNKQEKIHTGGKLNKCEECDKAFNRSLKLTAHKKILMEEK 326

Query: 293 PFQCPKCEKCFESEQILNEHSCFAARSGKIPSRFKRSYNYKTIVKKILAKLKRARSKKLD 352
           P++C +C K F     L  H        KI    ++ Y  K   K           KK+ 
Sbjct: 327 PYKCEECGKVFNQFSTLTRH--------KIIHTGEKPYKCKECGKAFNQSSNLTEHKKIH 378

Query: 353 NFQSEKKVFK--KSFLRNCDLISGEQSSEQTQRTFVGSLGKHGTYKTIGNRKKKTLTLPF 410
             +   K  +  K+F ++ +LI+                          +RK  +   P+
Sbjct: 379 TAEKSYKCEECGKAFNQHSNLIN--------------------------HRKIYSGEKPY 412

Query: 411 SWQNMGKNLKGILTTENILSIDNSVNKKDLSICGSSGEEFFNNCEVLQCGFSVPRENIRT 470
             +  GK      T      I           C  +  +  N  E          + I T
Sbjct: 413 KCEECGKAFNRSSTLTRHKKIHTGEKPYKCEECDRAFSQSSNLTE---------HKKIHT 463

Query: 471 RHKICPCDKCEKVFPSISKLKRHYLIHTGQRPFGCNICGKSFRQSAHLKRHEQTHNEKSP 530
             K   C++C K F   S L +H  IHTG++P+ C  CGK+F QS  L RH+  H ++  
Sbjct: 464 GEKPYKCEECGKAFNRFSTLTKHKRIHTGEKPYKCEECGKAFNQSYQLTRHKIVHTKEK- 522

Query: 531 YASLCQVEFGNFNNLSNHSGNNVNYNASQQCQAPGVQKYEVSESDQMSGVKAESQDFIPG 590
             + C+ EFG     S+H           +    G + Y+  E  ++    +        
Sbjct: 523 -LNKCE-EFGKAFKQSSH-------RTIHKIIHTGEKPYKCEEHGKVFNQSSNLTTQKII 573

Query: 591 STGQPCLPNVLLESEQSNPFCSYSEHQEKNDVFL----YRCSVCAKSFRSPSKLERHYLI 646
            TG+    N+    E    F  +S       ++     ++C  C K++   S L  H  I
Sbjct: 574 HTGE----NLYKFEEHGKAFNLFSNITNHKIIYTGEKPHKCEECGKAYNRFSNLTIHKRI 629

Query: 647 HAGQKPFECSVCGKTFRQAPHWKRHQLTHFKERPQ-----GKVVALDSVM 691
           H G+KP++C+ CGK F  +    RH++ H  E+P      GK   L S +
Sbjct: 630 HTGEKPYQCAECGKAFNCSSTLNRHKIIHTGEKPYKCKECGKAFNLSSTL 679



 Score =  197 bits (501), Expect = 3e-50
 Identities = 176/696 (25%), Positives = 286/696 (41%), Gaps = 129/696 (18%)

Query: 25  RPYVCNICFKHFETPSKLARHYLIHTGQKPFECDVCHKTFRQLVHLERHQLTHS--LPFK 82
           +PY C  C K F   S+L RH +IHT +KP +C+ C K F+Q  HL  H++ H+   P+K
Sbjct: 158 KPYKCEECGKAFNQSSQLTRHKIIHTEEKPNKCEECGKAFKQASHLTIHKIIHTGEKPYK 217

Query: 83  CSICQRHFKNLKTFVKHQQLH-------------------NETYQNNVKQVRRLLEAKQE 123
              C + F         + LH                   N T    +    +  + K+ 
Sbjct: 218 YEECGKVFSQSSHLTTQKILHTGENLYKCKECGKAFNLFSNLTNHKRIHAGEKPYKCKEC 277

Query: 124 KSMYGVYNTFTTEER----WALHPCSKSDPMYSMKRRKNIHA----------CTICGKMF 169
              + + +    +E+      L+ C + D  ++   +   H           C  CGK+F
Sbjct: 278 GRAFNISSNLNKQEKIHTGGKLNKCEECDKAFNRSLKLTAHKKILMEEKPYKCEECGKVF 337

Query: 170 PSQSKLDRHVLIHTGQRPFKCVLCTKSFRQSTHLKIHQLTHSEERPFQCCFCQKGFKIQS 229
              S L RH +IHTG++P+KC  C K+F QS++L  H+  H+ E+ ++C  C K F   S
Sbjct: 338 NQFSTLTRHKIIHTGEKPYKCKECGKAFNQSSNLTEHKKIHTAEKSYKCEECGKAFNQHS 397

Query: 230 KLLKHKQIHTRNKAFRALLLKKRRTESRPLPN--KLNANQGGFENGEIGE--SEENNPLD 285
            L+ H++I++  K ++     K    S  L    K++  +  ++  E     S+ +N  +
Sbjct: 398 NLINHRKIYSGEKPYKCEECGKAFNRSSTLTRHKKIHTGEKPYKCEECDRAFSQSSNLTE 457

Query: 286 VHSIYI--VPFQCPKCEKCFESEQILNEHSCFAARSGKIPSR-------FKRSYNYKTIV 336
              I+    P++C +C K F     L +H      +G+ P +       F +SY      
Sbjct: 458 HKKIHTGEKPYKCEECGKAFNRFSTLTKHK--RIHTGEKPYKCEECGKAFNQSYQ----- 510

Query: 337 KKILAKLKRARSK-KLDNFQSEKKVFKKSFLRNCDLI--SGEQSSEQTQRTFVGSLGKHG 393
              L + K   +K KL+  +   K FK+S  R    I  +GE+  +  +   V +   + 
Sbjct: 511 ---LTRHKIVHTKEKLNKCEEFGKAFKQSSHRTIHKIIHTGEKPYKCEEHGKVFNQSSNL 567

Query: 394 TYKTIGNRKKKTLTLPFSWQNMGK--NLKGILTTENILSIDNSVNKKDLSICGSSGEEFF 451
           T + I +  +      + ++  GK  NL   +T   I+      +K +   CG +   F 
Sbjct: 568 TTQKIIHTGENL----YKFEEHGKAFNLFSNITNHKIIYTGEKPHKCEE--CGKAYNRFS 621

Query: 452 NNCEVLQCGFSVPRENIRTRHKICPCDKCEKVFPSISKLKRHYLIHTGQRPFGCNICGKS 511
           N             + I T  K   C +C K F   S L RH +IHTG++P+ C  CGK+
Sbjct: 622 N---------LTIHKRIHTGEKPYQCAECGKAFNCSSTLNRHKIIHTGEKPYKCKECGKA 672

Query: 512 FRQSAHLKRHEQTHNEKSPY-ASLCQVEFGNFNNLSNHSGNNVNYNASQQCQAPGVQKYE 570
           F  S+ L  H++ H  + PY    C   F   +NL+ H                  +K  
Sbjct: 673 FNLSSTLTAHKKIHTGEKPYKCEECGKAFNQSSNLTTH------------------KKIH 714

Query: 571 VSESDQMSGVKAESQDFIPGSTGQPCLPNVLLESEQSNPFCSYSEHQ-----EKNDVFLY 625
            SE                    + C        +  N F S + H+     EK     Y
Sbjct: 715 TSEKPYKC---------------EEC-------GKSFNQFSSLNIHKIIHTGEKP----Y 748

Query: 626 RCSVCAKSFRSPSKLERHYLIHAGQKPFECSVCGKT 661
           +C    ++F   S L  H  IH G+KP++C   GKT
Sbjct: 749 KCGDYGRAFNLSSNLTTHKKIHTGEKPYKCEY-GKT 783


>gi|11386193 zinc finger protein 197 isoform 1 [Homo sapiens]
          Length = 1029

 Score =  202 bits (515), Expect = 6e-52
 Identities = 175/679 (25%), Positives = 271/679 (39%), Gaps = 88/679 (12%)

Query: 27  YVCNICFKHFETPSKLARHYLIHTGQKPFECDVCHKTFRQLVHLERHQLTHS--LPFKCS 84
           Y C++C KHF   S L  H  IHTG+KP +C  C K F Q   L  H   HS   P+KC+
Sbjct: 370 YKCDMCCKHFNKISHLINHRRIHTGEKPHKCKECGKGFIQRSSLLMHLRNHSGEKPYKCN 429

Query: 85  ICQRHFKNLKTFVKHQQLHNETYQNNVKQVRRLLEAKQEKSMYGVYNTFTTEERWALHPC 144
            C + F      + HQ++H        K+  +     +   +       + E  +  + C
Sbjct: 430 ECGKAFSQSAYLLNHQRIHTGEKPYKCKECGK--GFYRHSGLIIHLRRHSGERPYKCNEC 487

Query: 145 SK--SDPMY-----SMKRRKNIHACTICGKMFPSQSKLDRHVLIHTGQRPFKCVLCTKSF 197
            K  S   Y      + + +  + C  C K F  +  L  H  IH+G++P+KC  C K+F
Sbjct: 488 GKVFSQNAYLIDHQRLHKGEEPYKCNKCQKAFILKKSLILHQRIHSGEKPYKCDECGKTF 547

Query: 198 RQSTHLKIHQLTHSEERPFQCCFCQKGFKIQSKLLKHKQIHTRNKAF-----------RA 246
            Q+T+L  HQ  HS E P++C  C K F     LL H+++HT  K F           ++
Sbjct: 548 AQTTYLIDHQRLHSAENPYKCKECGKVFIRSKSLLLHQRVHTEKKTFGCKKCGKIFSSKS 607

Query: 247 LLLKKRRTESRPLPNKLNANQGGFENGEIGESEENNPLDVHSIYIVPFQCPKCEKCFESE 306
             +  +R  SR  P K       F         +     +H+    P++C +C K F  +
Sbjct: 608 NFIDHKRMHSREKPYKCTECGKAFTQSAYLFDHQR----LHN-GEKPYECNECGKVFILK 662

Query: 307 QILNEHSCFAARSGKIPSRFKRSYNYKTIVKKILAKLKRARSKKLDNFQS--EKKVFKKS 364
           + L  H  F           +  Y  K   K   +       ++L N +   E +   K+
Sbjct: 663 KSLILHQRFHTG--------ENLYECKDCGKVFGSNRNLIDHERLHNGEKPYECRECGKT 714

Query: 365 FLRNCDLISGEQSSEQTQRTFVGSLGKHGTYKT--IGNRKKKTLTLPFSWQNMGKNLKGI 422
           F+ +   +  ++   Q +       GK  +Y +  + +R+  T   PF     G+     
Sbjct: 715 FIMSKSFMVHQKLHTQEKAYKCEDCGKAFSYNSSLLVHRRIHTGEKPFECSECGRAFSSN 774

Query: 423 LTTENILSIDNSVNKKDLSICGSSGEEFFNNCEVLQCGFSVPRENIRTRHKICPCDKCEK 482
                   I +     +   CG         C +L+    +  + I TR K   C+ C K
Sbjct: 775 RNLIEHKRIHSGEKPYECDECG--------KCFILKKSL-IGHQRIHTREKSYKCNDCGK 825

Query: 483 VFPSISKLKRHYLIHTGQRPFGCNICGKSFRQSAHLKRHEQTHN-EKSPYASLCQVEFGN 541
           VF   S L  H  IHTG++P+ C+ CGK F  + +L  H++ H+ EK+    +C+    +
Sbjct: 826 VFSYRSNLIAHQRIHTGEKPYACSECGKGFTYNRNLIEHQRIHSGEKTYECHVCRKVLTS 885

Query: 542 FNNLSNHSGNNVNYNASQQCQAPGVQKYEVSESDQMSGVKAESQDFIPGSTGQPCLPNVL 601
             NL  H           Q    G + Y+ +E           +DF              
Sbjct: 886 SRNLMVH-----------QRIHTGEKPYKCNEC---------GKDF-------------- 911

Query: 602 LESEQSNPFCSYSEHQEKNDVFLYRCSVCAKSFRSPSKLERHYLIHAGQKPFECSVCGKT 661
             S+  N       H  +     Y C  C KSF S   L  H  IH G+KP+ C+ C K 
Sbjct: 912 --SQNKNLVVHQRMHTGEKP---YECDKCRKSFTSKRNLVGHQRIHTGEKPYGCNDCSKV 966

Query: 662 FRQAPHWKRHQLTHFKERP 680
           FRQ  +   HQ  H  E+P
Sbjct: 967 FRQRKNLTVHQKIHTDEKP 985



 Score =  192 bits (489), Expect = 7e-49
 Identities = 146/562 (25%), Positives = 230/562 (40%), Gaps = 110/562 (19%)

Query: 26   PYVCNICFKHFETPSKLARHYLIHTGQKPFECDVCHKTFRQLVHLERHQLTHSL--PFKC 83
            PY CN C K F     L  H  IH+G+KP++CD C KTF Q  +L  HQ  HS   P+KC
Sbjct: 509  PYKCNKCQKAFILKKSLILHQRIHSGEKPYKCDECGKTFAQTTYLIDHQRLHSAENPYKC 568

Query: 84   SICQRHFKNLKTFVKHQQLHNETYQNNVKQVRRLLEAKQE----KSMYGVYNTFTTEE-- 137
              C + F   K+ + HQ++H E      K+  ++  +K      K M+     +   E  
Sbjct: 569  KECGKVFIRSKSLLLHQRVHTEKKTFGCKKCGKIFSSKSNFIDHKRMHSREKPYKCTECG 628

Query: 138  -----------RWALH------PCSKSDPMYSMKRR----------KNIHACTICGKMFP 170
                          LH       C++   ++ +K+           +N++ C  CGK+F 
Sbjct: 629  KAFTQSAYLFDHQRLHNGEKPYECNECGKVFILKKSLILHQRFHTGENLYECKDCGKVFG 688

Query: 171  SQSKLDRHVLIHTGQRPFKCVLCTKSFRQSTHLKIHQLTHSEERPFQCCFCQKGFKIQSK 230
            S   L  H  +H G++P++C  C K+F  S    +HQ  H++E+ ++C  C K F   S 
Sbjct: 689  SNRNLIDHERLHNGEKPYECRECGKTFIMSKSFMVHQKLHTQEKAYKCEDCGKAFSYNSS 748

Query: 231  LLKHKQIHTRNKAFRALLLKKRRTESRPLPNKLNANQGGFENGEIGESEENNPLDVHSIY 290
            LL H++IHT  K F          E        ++N+   E+  I   E+          
Sbjct: 749  LLVHRRIHTGEKPF----------ECSECGRAFSSNRNLIEHKRIHSGEK---------- 788

Query: 291  IVPFQCPKCEKCFESEQILNEHSCFAARSGKIPSRFKRSYNYKTIVKKILAKLKRARSKK 350
              P++C +C KCF  ++ L  H     R        ++SY      K    +      ++
Sbjct: 789  --PYECDECGKCFILKKSLIGHQRIHTR--------EKSYKCNDCGKVFSYRSNLIAHQR 838

Query: 351  LDNFQSEKKVFK--KSFLRNCDLISGEQ--SSEQTQRTFVGSLGKHGTYKTIGNRKKKTL 406
            +   +      +  K F  N +LI  ++  S E+T    V                    
Sbjct: 839  IHTGEKPYACSECGKGFTYNRNLIEHQRIHSGEKTYECHV-------------------- 878

Query: 407  TLPFSWQNMGKNLKGILTTENILSIDNSVNKKDLSI-CGSSGEEFFNNCEVLQCGFSVPR 465
                         + +LT+   L +   ++  +    C   G++F  N  +      V  
Sbjct: 879  ------------CRKVLTSSRNLMVHQRIHTGEKPYKCNECGKDFSQNKNL------VVH 920

Query: 466  ENIRTRHKICPCDKCEKVFPSISKLKRHYLIHTGQRPFGCNICGKSFRQSAHLKRHEQTH 525
            + + T  K   CDKC K F S   L  H  IHTG++P+GCN C K FRQ  +L  H++ H
Sbjct: 921  QRMHTGEKPYECDKCRKSFTSKRNLVGHQRIHTGEKPYGCNDCSKVFRQRKNLTVHQKIH 980

Query: 526  NEKSPYASLCQVEFGNFNNLSN 547
             ++ P    C V    F+  SN
Sbjct: 981  TDEKPCE--CDVSEKEFSQTSN 1000



 Score =  186 bits (472), Expect = 6e-47
 Identities = 166/662 (25%), Positives = 264/662 (39%), Gaps = 88/662 (13%)

Query: 25   RPYVCNICFKHFETPSKLARHYLIHTGQKPFECDVCHKTFRQ----LVHLERHQLTHSLP 80
            +PY CN C K F   + L  H  IHTG+KP++C  C K F +    ++HL RH  +   P
Sbjct: 424  KPYKCNECGKAFSQSAYLLNHQRIHTGEKPYKCKECGKGFYRHSGLIIHLRRH--SGERP 481

Query: 81   FKCSICQRHFKNLKTFVKHQQLHN--ETYQNNVKQVRRLLEAKQEKSMYGVYNTFTTEER 138
            +KC+ C + F      + HQ+LH   E Y+ N  Q                   F  ++ 
Sbjct: 482  YKCNECGKVFSQNAYLIDHQRLHKGEEPYKCNKCQ-----------------KAFILKKS 524

Query: 139  WALHPCSKSDPMYSMKRRKNIHACTICGKMFPSQSKLDRHVLIHTGQRPFKCVLCTKSFR 198
              LH    S         +  + C  CGK F   + L  H  +H+ + P+KC  C K F 
Sbjct: 525  LILHQRIHSG--------EKPYKCDECGKTFAQTTYLIDHQRLHSAENPYKCKECGKVFI 576

Query: 199  QSTHLKIHQLTHSEERPFQCCFCQKGFKIQSKLLKHKQIHTRNKAFRALLLKKRRTESRP 258
            +S  L +HQ  H+E++ F C  C K F  +S  + HK++H+R K ++     K  T+S  
Sbjct: 577  RSKSLLLHQRVHTEKKTFGCKKCGKIFSSKSNFIDHKRMHSREKPYKCTECGKAFTQSAY 636

Query: 259  LPNKLNANQGGFENGEIGESEENNPLDVHSIYIVPFQCPKCEKCFESEQILNEHSCFAAR 318
            L          F++  +   E+            P++C +C K F  ++ L  H  F   
Sbjct: 637  L----------FDHQRLHNGEK------------PYECNECGKVFILKKSLILHQRFHTG 674

Query: 319  SGKIPSRFKRSYNYKTIVKKILAKLKRARSKKLDNFQS--EKKVFKKSFLRNCDLISGEQ 376
                    +  Y  K   K   +       ++L N +   E +   K+F+ +   +  ++
Sbjct: 675  --------ENLYECKDCGKVFGSNRNLIDHERLHNGEKPYECRECGKTFIMSKSFMVHQK 726

Query: 377  SSEQTQRTFVGSLGKHGTYKT--IGNRKKKTLTLPFSWQNMGKNLKGILTTENILSIDNS 434
               Q +       GK  +Y +  + +R+  T   PF     G+             I + 
Sbjct: 727  LHTQEKAYKCEDCGKAFSYNSSLLVHRRIHTGEKPFECSECGRAFSSNRNLIEHKRIHSG 786

Query: 435  VNKKDLSICGSSGEEFFNNCEVLQCGFSVPRENIRTRHKICPCDKCEKVFPSISKLKRHY 494
                +   CG         C +L+    +  + I TR K   C+ C KVF   S L  H 
Sbjct: 787  EKPYECDECGK--------CFILKKSL-IGHQRIHTREKSYKCNDCGKVFSYRSNLIAHQ 837

Query: 495  LIHTGQRPFGCNICGKSFRQSAHLKRHEQTHN-EKSPYASLCQVEFGNFNNLSNHSGNNV 553
             IHTG++P+ C+ CGK F  + +L  H++ H+ EK+    +C+    +  NL  H   + 
Sbjct: 838  RIHTGEKPYACSECGKGFTYNRNLIEHQRIHSGEKTYECHVCRKVLTSSRNLMVHQRIHT 897

Query: 554  NYNASQQCQAPGVQKYEVSESDQMSGVKAESQDFIPGSTGQPCLPNVLLESEQSNPFCSY 613
                  +C   G    + S++  +       Q    G     C       + + N     
Sbjct: 898  G-EKPYKCNECGK---DFSQNKNL----VVHQRMHTGEKPYECDKCRKSFTSKRNLVGHQ 949

Query: 614  SEHQEKNDVFLYRCSVCAKSFRSPSKLERHYLIHAGQKPFECSVCGKTFRQAPHWKRHQL 673
              H  +     Y C+ C+K FR    L  H  IH  +KP EC V  K F Q  +    Q 
Sbjct: 950  RIHTGEKP---YGCNDCSKVFRQRKNLTVHQKIHTDEKPCECDVSEKEFSQTSNLHLQQK 1006

Query: 674  TH 675
             H
Sbjct: 1007 IH 1008



 Score =  143 bits (361), Expect = 5e-34
 Identities = 147/584 (25%), Positives = 229/584 (39%), Gaps = 81/584 (13%)

Query: 157 KNIHACTICGKMFPSQSKLDRHVLIHTGQRPFKCVLCTKSFRQSTHLKIHQLTHSEERPF 216
           K  + C +C K F   S L  H  IHTG++P KC  C K F Q + L +H   HS E+P+
Sbjct: 367 KKFYKCDMCCKHFNKISHLINHRRIHTGEKPHKCKECGKGFIQRSSLLMHLRNHSGEKPY 426

Query: 217 QCCFCQKGFKIQSKLLKHKQIHTRNKAFRAL-----------LLKKRRTESRPLPNKLN- 264
           +C  C K F   + LL H++IHT  K ++             L+   R  S   P K N 
Sbjct: 427 KCNECGKAFSQSAYLLNHQRIHTGEKPYKCKECGKGFYRHSGLIIHLRRHSGERPYKCNE 486

Query: 265 ------ANQGGFENGEIGESEENNPLD-VHSIYIV---------------PFQCPKCEKC 302
                  N    ++  + + EE    +     +I+               P++C +C K 
Sbjct: 487 CGKVFSQNAYLIDHQRLHKGEEPYKCNKCQKAFILKKSLILHQRIHSGEKPYKCDECGKT 546

Query: 303 FESEQILNEHSCFAARSGKIPSRFKRSYNYKTIVKKILAKLKRARSKKLDNFQSEKKVF- 361
           F     L +H      S + P + K         K +L   +    KK    +   K+F 
Sbjct: 547 FAQTTYLIDHQ--RLHSAENPYKCKECGKVFIRSKSLLLHQRVHTEKKTFGCKKCGKIFS 604

Query: 362 -KKSFLRNCDLISGEQSSEQTQ--RTFVGSLGKHGTYKTIGNRK-------------KKT 405
            K +F+ +  + S E+  + T+  + F  S       +     K             KK+
Sbjct: 605 SKSNFIDHKRMHSREKPYKCTECGKAFTQSAYLFDHQRLHNGEKPYECNECGKVFILKKS 664

Query: 406 LTLPFSWQNMGKNL-------KGILTTENILSIDNSVNKKDLSICGSSGEEFFNNCEVLQ 458
           L L   + + G+NL       K   +  N++  +   N +    C   G+ F     ++ 
Sbjct: 665 LILHQRF-HTGENLYECKDCGKVFGSNRNLIDHERLHNGEKPYECRECGKTF-----IMS 718

Query: 459 CGFSVPRENIRTRHKICPCDKCEKVFPSISKLKRHYLIHTGQRPFGCNICGKSFRQSAHL 518
             F V  + + T+ K   C+ C K F   S L  H  IHTG++PF C+ CG++F  + +L
Sbjct: 719 KSFMV-HQKLHTQEKAYKCEDCGKAFSYNSSLLVHRRIHTGEKPFECSECGRAFSSNRNL 777

Query: 519 KRHEQTHNEKSPY-ASLCQVEFGNFNNLSNHSGNNVNYNASQQCQAPGVQKYEVSESDQM 577
             H++ H+ + PY    C   F    +L  H   +     S +C   G      S     
Sbjct: 778 IEHKRIHSGEKPYECDECGKCFILKKSLIGHQRIHTR-EKSYKCNDCGKVFSYRSNLIAH 836

Query: 578 SGVKAESQDFIPGSTGQPCLPNVLLESEQSNPFCSYSEHQE-KNDVFLYRCSVCAKSFRS 636
             +    + +     G+    N  L            EHQ   +    Y C VC K   S
Sbjct: 837 QRIHTGEKPYACSECGKGFTYNRNL-----------IEHQRIHSGEKTYECHVCRKVLTS 885

Query: 637 PSKLERHYLIHAGQKPFECSVCGKTFRQAPHWKRHQLTHFKERP 680
              L  H  IH G+KP++C+ CGK F Q  +   HQ  H  E+P
Sbjct: 886 SRNLMVHQRIHTGEKPYKCNECGKDFSQNKNLVVHQRMHTGEKP 929



 Score =  129 bits (323), Expect = 1e-29
 Identities = 71/231 (30%), Positives = 113/231 (48%), Gaps = 11/231 (4%)

Query: 23  RNRPYVCNICFKHFETPSKLARHYLIHTGQKPFECDVCHKTFRQLVHLERHQLTHS--LP 80
           + + Y C  C K F   S L  H  IHTG+KPFEC  C + F    +L  H+  HS   P
Sbjct: 730 QEKAYKCEDCGKAFSYNSSLLVHRRIHTGEKPFECSECGRAFSSNRNLIEHKRIHSGEKP 789

Query: 81  FKCSICQRHFKNLKTFVKHQQLHNETYQNNVKQVRRLLEAKQEKSMYGVYNTFTTEERWA 140
           ++C  C + F   K+ + HQ++H            ++   +   ++       T E+ +A
Sbjct: 790 YECDECGKCFILKKSLIGHQRIHTREKSYKCNDCGKVFSYRS--NLIAHQRIHTGEKPYA 847

Query: 141 LHPCSKSDPMY-SMKRRKNIHA------CTICGKMFPSQSKLDRHVLIHTGQRPFKCVLC 193
              C K      ++   + IH+      C +C K+  S   L  H  IHTG++P+KC  C
Sbjct: 848 CSECGKGFTYNRNLIEHQRIHSGEKTYECHVCRKVLTSSRNLMVHQRIHTGEKPYKCNEC 907

Query: 194 TKSFRQSTHLKIHQLTHSEERPFQCCFCQKGFKIQSKLLKHKQIHTRNKAF 244
            K F Q+ +L +HQ  H+ E+P++C  C+K F  +  L+ H++IHT  K +
Sbjct: 908 GKDFSQNKNLVVHQRMHTGEKPYECDKCRKSFTSKRNLVGHQRIHTGEKPY 958



 Score =  125 bits (313), Expect = 2e-28
 Identities = 121/518 (23%), Positives = 201/518 (38%), Gaps = 115/518 (22%)

Query: 184 GQRPFKCVLCTKSFRQSTHLKIHQLTHSEERPFQCCFCQKGFKIQSKLLKHKQIHTRNKA 243
           G++ +KC +C K F + +HL  H+  H+ E+P +C  C KGF  +S LL H + H+  K 
Sbjct: 366 GKKFYKCDMCCKHFNKISHLINHRRIHTGEKPHKCKECGKGFIQRSSLLMHLRNHSGEKP 425

Query: 244 FRALLLKKRRTESRPLPN--KLNANQGGFENGEIGESEENNPLDVHSIYIV--------- 292
           ++     K  ++S  L N  +++  +  ++  E G+         HS  I+         
Sbjct: 426 YKCNECGKAFSQSAYLLNHQRIHTGEKPYKCKECGKGFYR-----HSGLIIHLRRHSGER 480

Query: 293 PFQCPKCEKCFESEQILNEHSCFAARSGKIPSRFKRSYNYKTIVKKILAKLKRARSKKLD 352
           P++C +C K F     L +H                             +L +       
Sbjct: 481 PYKCNECGKVFSQNAYLIDHQ----------------------------RLHKGEEPYKC 512

Query: 353 NFQSEKKVFKKSFLRNCDLISGEQ--SSEQTQRTFVGSLGKHGTYKTIGNRKKKTLTLPF 410
           N   +  + KKS + +  + SGE+    ++  +TF  +     TY               
Sbjct: 513 NKCQKAFILKKSLILHQRIHSGEKPYKCDECGKTFAQT-----TY--------------- 552

Query: 411 SWQNMGKNLKGILTTENILSIDNSVNKKDLSICGSSGEEFFNNCEVLQCGFSVPRENIRT 470
                      ++  + + S +N         C   G+ F  +  +L        + + T
Sbjct: 553 -----------LIDHQRLHSAENPYK------CKECGKVFIRSKSLLL------HQRVHT 589

Query: 471 RHKICPCDKCEKVFPSISKLKRHYLIHTGQRPFGCNICGKSFRQSAHLKRHEQTHNEKSP 530
             K   C KC K+F S S    H  +H+ ++P+ C  CGK+F QSA+L  H++ HN + P
Sbjct: 590 EKKTFGCKKCGKIFSSKSNFIDHKRMHSREKPYKCTECGKAFTQSAYLFDHQRLHNGEKP 649

Query: 531 Y-ASLCQVEFGNFNNLSNHSGNNVNYNASQQCQAPGVQKYEVSESDQMSGVKAESQDFIP 589
           Y  + C   F    +L  H   +   N            YE  +  ++ G      D   
Sbjct: 650 YECNECGKVFILKKSLILHQRFHTGENL-----------YECKDCGKVFGSNRNLIDHER 698

Query: 590 GSTGQ------PCLPNVLLESEQSNPFCSYSEHQE-KNDVFLYRCSVCAKSFRSPSKLER 642
              G+       C    ++         S+  HQ+       Y+C  C K+F   S L  
Sbjct: 699 LHNGEKPYECRECGKTFIMSK-------SFMVHQKLHTQEKAYKCEDCGKAFSYNSSLLV 751

Query: 643 HYLIHAGQKPFECSVCGKTFRQAPHWKRHQLTHFKERP 680
           H  IH G+KPFECS CG+ F    +   H+  H  E+P
Sbjct: 752 HRRIHTGEKPFECSECGRAFSSNRNLIEHKRIHSGEKP 789



 Score =  121 bits (303), Expect = 2e-27
 Identities = 66/225 (29%), Positives = 110/225 (48%), Gaps = 25/225 (11%)

Query: 23  RNRPYVCNICFKHFETPSKLARHYLIHTGQKPFECDVCHKTFRQLVHLERHQLTHSLP-- 80
           R +PY C  C K F   + L  H  +H G+KP+EC+ C K F     L  HQ  H+    
Sbjct: 618 REKPYKCTECGKAFTQSAYLFDHQRLHNGEKPYECNECGKVFILKKSLILHQRFHTGENL 677

Query: 81  FKCSICQRHFKNLKTFVKHQQLHNETYQNNVKQVRRLLEAKQEKSMYGVYNTFTTEERWA 140
           ++C  C + F + +  + H++LHN       ++  +               TF   + + 
Sbjct: 678 YECKDCGKVFGSNRNLIDHERLHNGEKPYECRECGK---------------TFIMSKSFM 722

Query: 141 LHPCSKSDPMYSMKRRKNIHACTICGKMFPSQSKLDRHVLIHTGQRPFKCVLCTKSFRQS 200
           +H          +  ++  + C  CGK F   S L  H  IHTG++PF+C  C ++F  +
Sbjct: 723 VHQ--------KLHTQEKAYKCEDCGKAFSYNSSLLVHRRIHTGEKPFECSECGRAFSSN 774

Query: 201 THLKIHQLTHSEERPFQCCFCQKGFKIQSKLLKHKQIHTRNKAFR 245
            +L  H+  HS E+P++C  C K F ++  L+ H++IHTR K+++
Sbjct: 775 RNLIEHKRIHSGEKPYECDECGKCFILKKSLIGHQRIHTREKSYK 819



 Score =  118 bits (296), Expect = 2e-26
 Identities = 71/229 (31%), Positives = 116/229 (50%), Gaps = 21/229 (9%)

Query: 25   RPYVCNICFKHFETPSKLARHYLIHTGQKPFECDVCHKTFRQLVHLERHQLTHS--LPFK 82
            +PY C+ C K F     L  H  IHT +K ++C+ C K F    +L  HQ  H+   P+ 
Sbjct: 788  KPYECDECGKCFILKKSLIGHQRIHTREKSYKCNDCGKVFSYRSNLIAHQRIHTGEKPYA 847

Query: 83   CSICQRHFKNLKTFVKHQQLHN--ETYQNNVKQVRRLLEAKQEKSMYGVYNTFTTEERWA 140
            CS C + F   +  ++HQ++H+  +TY+ +V   R++L + +   ++      T E+ + 
Sbjct: 848  CSECGKGFTYNRNLIEHQRIHSGEKTYECHV--CRKVLTSSRNLMVH--QRIHTGEKPYK 903

Query: 141  LHPCSKSDPMYSMKRRKNIHA----------CTICGKMFPSQSKLDRHVLIHTGQRPFKC 190
             + C K    +S  +   +H           C  C K F S+  L  H  IHTG++P+ C
Sbjct: 904  CNECGKD---FSQNKNLVVHQRMHTGEKPYECDKCRKSFTSKRNLVGHQRIHTGEKPYGC 960

Query: 191  VLCTKSFRQSTHLKIHQLTHSEERPFQCCFCQKGFKIQSKLLKHKQIHT 239
              C+K FRQ  +L +HQ  H++E+P +C   +K F   S L   ++IHT
Sbjct: 961  NDCSKVFRQRKNLTVHQKIHTDEKPCECDVSEKEFSQTSNLHLQQKIHT 1009



 Score = 94.7 bits (234), Expect = 2e-19
 Identities = 59/203 (29%), Positives = 94/203 (46%), Gaps = 17/203 (8%)

Query: 23   RNRPYVCNICFKHFETPSKLARHYLIHTGQKPFECDVCHKTFRQLVHLERHQLTHS--LP 80
            R + Y CN C K F   S L  H  IHTG+KP+ C  C K F    +L  HQ  HS    
Sbjct: 814  REKSYKCNDCGKVFSYRSNLIAHQRIHTGEKPYACSECGKGFTYNRNLIEHQRIHSGEKT 873

Query: 81   FKCSICQRHFKNLKTFVKHQQLHNETYQNNVKQVRRLLEAKQEKSMYGVYNTFTTEERWA 140
            ++C +C++   + +  + HQ++H         +  +  +  Q K++       T E+ + 
Sbjct: 874  YECHVCRKVLTSSRNLMVHQRIHTGEKPYKCNECGK--DFSQNKNLVVHQRMHTGEKPYE 931

Query: 141  LHPCSKSDPMYSMKRR----KNIHA------CTICGKMFPSQSKLDRHVLIHTGQRPFKC 190
               C KS   ++ KR     + IH       C  C K+F  +  L  H  IHT ++P +C
Sbjct: 932  CDKCRKS---FTSKRNLVGHQRIHTGEKPYGCNDCSKVFRQRKNLTVHQKIHTDEKPCEC 988

Query: 191  VLCTKSFRQSTHLKIHQLTHSEE 213
             +  K F Q+++L + Q  H+ E
Sbjct: 989  DVSEKEFSQTSNLHLQQKIHTIE 1011



 Score = 89.0 bits (219), Expect = 1e-17
 Identities = 88/372 (23%), Positives = 152/372 (40%), Gaps = 49/372 (13%)

Query: 329 SYNYKTIVKKILAKLKRARSKKLDNFQSEKKVFKKS------FLRNCD--LISGEQSSEQ 380
           S  ++T+ +      K + S++ D+ +   K  + S      F   C+  +++ +  +E 
Sbjct: 255 SLEWETMTENEEVTSKPSSSQRADSHKGTSKRLQGSVPQVLDFEEECEWQVLASQWGNET 314

Query: 381 TQRTFVGSLGKHGTYKTIG--NRKKKTLTLPFSWQNMGKNLKGILTTENILSIDNSVNKK 438
            +R          T K +    R KK  T P       K L   LT  + +S        
Sbjct: 315 DERA--------DTVKKVSLCERDKKKRTPPEKQGQKWKELGDSLTFGSAISE------- 359

Query: 439 DLSICGSSGEEFFNNCEVLQCGFS-----VPRENIRTRHKICPCDKCEKVFPSISKLKRH 493
             S+ G+ G++F+  C++    F+     +    I T  K   C +C K F   S L  H
Sbjct: 360 --SLIGTEGKKFYK-CDMCCKHFNKISHLINHRRIHTGEKPHKCKECGKGFIQRSSLLMH 416

Query: 494 YLIHTGQRPFGCNICGKSFRQSAHLKRHEQTHNEKSPYASLCQVEFGNFNNLSNHSGNNV 553
              H+G++P+ CN CGK+F QSA+L  H++ H  + PY   C+ E G       HSG  +
Sbjct: 417 LRNHSGEKPYKCNECGKAFSQSAYLLNHQRIHTGEKPYK--CK-ECGK--GFYRHSGLII 471

Query: 554 NYNASQQCQAPGVQKYEVSESDQMSGVKA---ESQDFIPGSTGQPCLPNVLLESEQSNPF 610
           +          G + Y+ +E  ++    A   + Q    G     C         + +  
Sbjct: 472 HLRRHS-----GERPYKCNECGKVFSQNAYLIDHQRLHKGEEPYKCNKCQKAFILKKSLI 526

Query: 611 CSYSEHQEKNDVFLYRCSVCAKSFRSPSKLERHYLIHAGQKPFECSVCGKTFRQAPHWKR 670
                H  +     Y+C  C K+F   + L  H  +H+ + P++C  CGK F ++     
Sbjct: 527 LHQRIHSGEKP---YKCDECGKTFAQTTYLIDHQRLHSAENPYKCKECGKVFIRSKSLLL 583

Query: 671 HQLTHFKERPQG 682
           HQ  H +++  G
Sbjct: 584 HQRVHTEKKTFG 595


>gi|55769537 zinc finger protein 658 [Homo sapiens]
          Length = 1059

 Score =  201 bits (510), Expect = 2e-51
 Identities = 169/667 (25%), Positives = 276/667 (41%), Gaps = 52/667 (7%)

Query: 32   CFKHFETPSKLARHYLIHTGQKPFECDVCHKTFRQLVHLERHQLTHS--LPFKCSICQRH 89
            C K F   + L +H   H+G+K ++ + C K+F    H  +H  T+     ++C+ C + 
Sbjct: 389  CRKSFYRKAHLIQHQRPHSGEKTYQYEECAKSFCSSSHPIQHPGTYVGFKLYECNECGKA 448

Query: 90   FKNLKTFVKHQQLHNETYQNNVKQVRRLLEAKQEKSMYGVYNTFTTEERWALHPCSKSDP 149
            F       KH ++H +    +     R      +  + G   T    E        K+  
Sbjct: 449  FCQNSNLSKHLRIHTKEKPCDNNGCGR----SYKSPLIGHQKTDAEMELCGGSEYGKTSH 504

Query: 150  MYSMKR---RKNIHACTICGKMFPSQSKLDRHVLIHTGQRPFKCVLCTKSFRQSTHLKIH 206
            +   +R    +  + C  CGK F   S L  H  IHTG++P++CV C K+F   THL +H
Sbjct: 505  LKGHQRILMGEKPYECIECGKTFSKTSHLRAHQRIHTGEKPYECVECEKTFSHKTHLSVH 564

Query: 207  QLTHSEERPFQCCFCQKGFKIQSKLLKHKQIHTRNKAFRALLLKKRRTESRPLP--NKLN 264
            Q  H+ E+P++C  C K F   S L  H++IHT  K +     +K    +  L   ++++
Sbjct: 565  QRVHTGEKPYECNDCGKSFTYNSALRAHQRIHTGEKPYECSDCEKTFAHNSALRAHHRIH 624

Query: 265  ANQGGFENGEIGESEEN-NPLDVHSIYIV---PFQCPKCEKCFESEQILNEHSCFAARSG 320
              +  +E  E G S  + + L  H        P++C +C + F     L  H      +G
Sbjct: 625  TGEKPYECNECGRSFAHISVLKAHQRIHTGEKPYECNECGRSFTYNSALRAHQ--RIHTG 682

Query: 321  KIPSRFKRSYNYKTIVKKILAKLKR---ARSKKLDNFQSEKKVFKKSFLR-NCDLISGEQ 376
            + P  ++ S   KT       K+ +      K  +  + EK     S LR + ++ +GE+
Sbjct: 683  RKP--YECSDCEKTFAHNSALKIHQRIHTGEKPYECNECEKTFAHNSALRAHQNIHTGEK 740

Query: 377  SSEQTQ--RTFVGSLGKHGTYKTIGNRKKKTLTLPFSWQNMGKNLKGILTTENILSIDNS 434
              E ++  +TF     +  T++ I   +K     P+     GK             I   
Sbjct: 741  LYECSECGKTFFQKT-RLSTHRRIHTGEK-----PYECSKCGKTFSQKSYLSGHERIHTG 794

Query: 435  VNKKDLSICGSSGEEFFNNCEVLQCGFSVPRENIRTRHKICPCDKCEKVFPSISKLKRHY 494
                + ++CG +          +     +  + I T  K   C++C K F   + L  H 
Sbjct: 795  EKPYECNVCGKT---------FVYKAALIVHQRIHTGEKPYECNQCGKTFSQRTHLCAHQ 845

Query: 495  LIHTGQRPFGCNICGKSFRQSAHLKRHEQTHNEKSPY-ASLCQVEFGNFNNLSNHSGNNV 553
             IHTG++P+ CN CGK+F  ++ L+ H + H  + PY  + C   F   ++L  H     
Sbjct: 846  RIHTGEKPYECNECGKTFADNSALRAHHRIHTGEKPYECNDCGKTFSKTSHLRAHLRTRS 905

Query: 554  NYNASQQCQAPGVQKYEVSESDQMSGVKAESQDFIPGSTGQPCLPNVLLESEQSNPFCSY 613
                  +C   G    E S       V    + +     G+P   N  L   Q       
Sbjct: 906  G-EKPYECSECGKTFSEKSYVSAHQRVHTGEKPYECNVCGKPFAHNSTLRVHQR------ 958

Query: 614  SEHQEKNDVFLYRCSVCAKSFRSPSKLERHYLIHAGQKPFECSVCGKTFRQAPHWKRHQL 673
                EK+    Y C+ C K+F   S L  H  IH G+KP+EC+ CGK F Q    + HQ 
Sbjct: 959  IHTGEKS----YECNDCGKTFSQKSHLSAHQRIHTGEKPYECNECGKAFAQNSTLRVHQR 1014

Query: 674  THFKERP 680
             H  E+P
Sbjct: 1015 IHTGEKP 1021



 Score =  187 bits (474), Expect = 4e-47
 Identities = 142/540 (26%), Positives = 223/540 (41%), Gaps = 59/540 (10%)

Query: 25   RPYVCNICFKHFETPSKLARHYLIHTGQKPFECDVCHKTFRQLVHLERHQLTHS--LPFK 82
            +PY C  C K F   S L  H  IHTG+KP+EC  C KTF    HL  HQ  H+   P++
Sbjct: 516  KPYECIECGKTFSKTSHLRAHQRIHTGEKPYECVECEKTFSHKTHLSVHQRVHTGEKPYE 575

Query: 83   CSICQRHFKNLKTFVKHQQLHNETYQNNVKQVRRLLEAKQEKSMYGVYNTFTTEERWALH 142
            C+ C + F        HQ++H            +        ++   +   T E+ +  +
Sbjct: 576  CNDCGKSFTYNSALRAHQRIHTGEKPYECSDCEKTF--AHNSALRAHHRIHTGEKPYECN 633

Query: 143  PCSKSDPMYS-MKRRKNIHA------CTICGKMFPSQSKLDRHVLIHTGQRPFKCVLCTK 195
             C +S    S +K  + IH       C  CG+ F   S L  H  IHTG++P++C  C K
Sbjct: 634  ECGRSFAHISVLKAHQRIHTGEKPYECNECGRSFTYNSALRAHQRIHTGRKPYECSDCEK 693

Query: 196  SFRQSTHLKIHQLTHSEERPFQCCFCQKGFKIQSKLLKHKQIHTRNKAFRALLLKKRRTE 255
            +F  ++ LKIHQ  H+ E+P++C  C+K F   S L  H+ IHT  K +      K   +
Sbjct: 694  TFAHNSALKIHQRIHTGEKPYECNECEKTFAHNSALRAHQNIHTGEKLYECSECGKTFFQ 753

Query: 256  SRPLPNKLNANQGGFENGEIGESEENNPLDVHSIYIVPFQCPKCEKCFESEQILNEHSCF 315
               L      + G                        P++C KC K F  +  L+ H   
Sbjct: 754  KTRLSTHRRIHTGE----------------------KPYECSKCGKTFSQKSYLSGHE-- 789

Query: 316  AARSGKIPSRFKRSYNYKTIVKK---ILAKLKRARSKKLDNFQSEKKVFKKSFL-RNCDL 371
               +G+ P  ++ +   KT V K   I+ +      K  +  Q  K   +++ L  +  +
Sbjct: 790  RIHTGEKP--YECNVCGKTFVYKAALIVHQRIHTGEKPYECNQCGKTFSQRTHLCAHQRI 847

Query: 372  ISGEQSSE--QTQRTFVGSLGKHGTYKTIGNRKKKTLTLPFSWQNMGKNLKGILTTENIL 429
             +GE+  E  +  +TF  +      ++     K      P+   + GK           L
Sbjct: 848  HTGEKPYECNECGKTFADNSALRAHHRIHTGEK------PYECNDCGKTFSKTSHLRAHL 901

Query: 430  SIDNSVNKKDLSICGSSGEEFFNNCEVLQCGFSVPRENIRTRHKICPCDKCEKVFPSISK 489
               +     + S CG +  E           +    + + T  K   C+ C K F   S 
Sbjct: 902  RTRSGEKPYECSECGKTFSE---------KSYVSAHQRVHTGEKPYECNVCGKPFAHNST 952

Query: 490  LKRHYLIHTGQRPFGCNICGKSFRQSAHLKRHEQTHNEKSPY-ASLCQVEFGNFNNLSNH 548
            L+ H  IHTG++ + CN CGK+F Q +HL  H++ H  + PY  + C   F   + L  H
Sbjct: 953  LRVHQRIHTGEKSYECNDCGKTFSQKSHLSAHQRIHTGEKPYECNECGKAFAQNSTLRVH 1012



 Score =  164 bits (415), Expect = 3e-40
 Identities = 173/717 (24%), Positives = 285/717 (39%), Gaps = 90/717 (12%)

Query: 30   NICFKHFETPSKLARHYLIHTGQKPFECDVCHKTFRQLVHLERHQLTHS-----LPFKCS 84
            N C ++F   S    H     G K  E + C     Q +    HQ  H+     L  +  
Sbjct: 328  NKCEENFSQSSAHIVHQKTQAGDKFGEHNECTDALYQKLDFTAHQRIHTEDKFYLSDEHG 387

Query: 85   ICQRHFKNLKTFVKHQQLHN--ETYQNNVKQVRRLLEAKQEKSMYGVYNTF--------- 133
             C++ F      ++HQ+ H+  +TYQ   +  +    +       G Y  F         
Sbjct: 388  KCRKSFYRKAHLIQHQRPHSGEKTYQYE-ECAKSFCSSSHPIQHPGTYVGFKLYECNECG 446

Query: 134  ----------------TTEERWALHPCSKSDPMYSMKRRKNIHACTIC-GKMFPSQSKLD 176
                            T E+    + C +S     +  +K      +C G  +   S L 
Sbjct: 447  KAFCQNSNLSKHLRIHTKEKPCDNNGCGRSYKSPLIGHQKTDAEMELCGGSEYGKTSHLK 506

Query: 177  RHVLIHTGQRPFKCVLCTKSFRQSTHLKIHQLTHSEERPFQCCFCQKGFKIQSKLLKHKQ 236
             H  I  G++P++C+ C K+F +++HL+ HQ  H+ E+P++C  C+K F  ++ L  H++
Sbjct: 507  GHQRILMGEKPYECIECGKTFSKTSHLRAHQRIHTGEKPYECVECEKTFSHKTHLSVHQR 566

Query: 237  IHTRNKAFRALLLKKRRTESRPL--PNKLNANQGGFENGEIGES-EENNPLDVHSIYIV- 292
            +HT  K +      K  T +  L    +++  +  +E  +  ++   N+ L  H      
Sbjct: 567  VHTGEKPYECNDCGKSFTYNSALRAHQRIHTGEKPYECSDCEKTFAHNSALRAHHRIHTG 626

Query: 293  --PFQCPKCEKCFESEQILNEHSCFAARSGKIP---SRFKRSYNYKTIVKKILAKLKRAR 347
              P++C +C + F    +L  H      +G+ P   +   RS+ Y + + +   ++   R
Sbjct: 627  EKPYECNECGRSFAHISVLKAHQ--RIHTGEKPYECNECGRSFTYNSAL-RAHQRIHTGR 683

Query: 348  SKKLDNFQSEKKVFKKSFLRNCDLI-SGEQSSE--QTQRTFV--GSLGKHGTYKTIGNRK 402
             K  +    EK     S L+    I +GE+  E  + ++TF    +L  H    T G + 
Sbjct: 684  -KPYECSDCEKTFAHNSALKIHQRIHTGEKPYECNECEKTFAHNSALRAHQNIHT-GEKL 741

Query: 403  KKTLTLPFSWQNMGKNLKGILTTENILSIDNSVNKKDLSICGSSGEEFFNNCEVLQCGFS 462
                   +     GK             I       + S CG +           Q  + 
Sbjct: 742  -------YECSECGKTFFQKTRLSTHRRIHTGEKPYECSKCGKT---------FSQKSYL 785

Query: 463  VPRENIRTRHKICPCDKCEKVFPSISKLKRHYLIHTGQRPFGCNICGKSFRQSAHLKRHE 522
               E I T  K   C+ C K F   + L  H  IHTG++P+ CN CGK+F Q  HL  H+
Sbjct: 786  SGHERIHTGEKPYECNVCGKTFVYKAALIVHQRIHTGEKPYECNQCGKTFSQRTHLCAHQ 845

Query: 523  QTHNEKSPY-ASLCQVEFGNFNNLSNHSGNNVNYNASQQCQAPGVQKYEVSESDQMSGVK 581
            + H  + PY  + C   F + + L  H   +            G + YE ++  +     
Sbjct: 846  RIHTGEKPYECNECGKTFADNSALRAHHRIHT-----------GEKPYECNDCGKTFSKT 894

Query: 582  AESQDFIPGSTGQPCLPNVLLESEQSNPFCSY-SEHQE-KNDVFLYRCSVCAKSFRSPSK 639
            +  +  +   +G+   P    E  ++    SY S HQ        Y C+VC K F   S 
Sbjct: 895  SHLRAHLRTRSGEK--PYECSECGKTFSEKSYVSAHQRVHTGEKPYECNVCGKPFAHNST 952

Query: 640  LERHYLIHAGQKPFECSVCGKTFRQAPHWKRHQLTHFKERPQ-----GKVVALDSVM 691
            L  H  IH G+K +EC+ CGKTF Q  H   HQ  H  E+P      GK  A +S +
Sbjct: 953  LRVHQRIHTGEKSYECNDCGKTFSQKSHLSAHQRIHTGEKPYECNECGKAFAQNSTL 1009



 Score =  161 bits (408), Expect = 2e-39
 Identities = 157/675 (23%), Positives = 260/675 (38%), Gaps = 95/675 (14%)

Query: 27   YVCNICFKHFETPSKLARHYLIHTGQKPFECDVCHKTFR--------------------- 65
            Y CN C K F   S L++H  IHT +KP + + C ++++                     
Sbjct: 440  YECNECGKAFCQNSNLSKHLRIHTKEKPCDNNGCGRSYKSPLIGHQKTDAEMELCGGSEY 499

Query: 66   -QLVHLERHQ--LTHSLPFKCSICQRHFKNLKTFVKHQQLHNETYQNNVKQVRRLLEAKQ 122
             +  HL+ HQ  L    P++C  C + F        HQ++H         +  +    K 
Sbjct: 500  GKTSHLKGHQRILMGEKPYECIECGKTFSKTSHLRAHQRIHTGEKPYECVECEKTFSHKT 559

Query: 123  EKSMYGVYNTFTTEERWALHPCSKSDPMYS-MKRRKNIHA------CTICGKMFPSQSKL 175
              S++      T E+ +  + C KS    S ++  + IH       C+ C K F   S L
Sbjct: 560  HLSVH--QRVHTGEKPYECNDCGKSFTYNSALRAHQRIHTGEKPYECSDCEKTFAHNSAL 617

Query: 176  DRHVLIHTGQRPFKCVLCTKSFRQSTHLKIHQLTHSEERPFQCCFCQKGFKIQSKLLKHK 235
              H  IHTG++P++C  C +SF   + LK HQ  H+ E+P++C  C + F   S L  H+
Sbjct: 618  RAHHRIHTGEKPYECNECGRSFAHISVLKAHQRIHTGEKPYECNECGRSFTYNSALRAHQ 677

Query: 236  QIHTRNKAFRALLLKKRRTESRPLPNKLNANQGGFENGEIGESEENNPLDVHSIYIVPFQ 295
            +IHT  K +     +K    +  L      + G                        P++
Sbjct: 678  RIHTGRKPYECSDCEKTFAHNSALKIHQRIHTGE----------------------KPYE 715

Query: 296  CPKCEKCFESEQILNEHSCFAARSGKIPSRFKRSYNYKTIVKKILAKLKR---ARSKKLD 352
            C +CEK F     L  H      +G+    ++ S   KT  +K      R      K  +
Sbjct: 716  CNECEKTFAHNSALRAHQ--NIHTGE--KLYECSECGKTFFQKTRLSTHRRIHTGEKPYE 771

Query: 353  NFQSEKKVFKKSFLRNCDLI-SGEQSSEQTQRTFVGSLGKHGTYKT--IGNRKKKTLTLP 409
              +  K   +KS+L   + I +GE+  E          GK   YK   I +++  T   P
Sbjct: 772  CSKCGKTFSQKSYLSGHERIHTGEKPYE------CNVCGKTFVYKAALIVHQRIHTGEKP 825

Query: 410  FSWQNMGKNLKGILTTENILSIDNSVNKKDLSI-CGSSGEEFFNNCEVLQCGFSVPRENI 468
            +     GK      +    L     ++  +    C   G+ F +N  +           I
Sbjct: 826  YECNQCGKT----FSQRTHLCAHQRIHTGEKPYECNECGKTFADNSALR------AHHRI 875

Query: 469  RTRHKICPCDKCEKVFPSISKLKRHYLIHTGQRPFGCNICGKSFRQSAHLKRHEQTHNEK 528
             T  K   C+ C K F   S L+ H    +G++P+ C+ CGK+F + +++  H++ H  +
Sbjct: 876  HTGEKPYECNDCGKTFSKTSHLRAHLRTRSGEKPYECSECGKTFSEKSYVSAHQRVHTGE 935

Query: 529  SPY-ASLCQVEFGNFNNLSNHSGNNVNYNASQQCQAPGVQKYEVSESDQMSGVKAESQDF 587
             PY  ++C   F + + L  H   +     S +C   G    + S       +    + +
Sbjct: 936  KPYECNVCGKPFAHNSTLRVHQRIHTG-EKSYECNDCGKTFSQKSHLSAHQRIHTGEKPY 994

Query: 588  IPGSTGQPCLPNVLLESEQSNPFCSYSEHQEKNDVFLYRCSVCAKSFRSPSKLERHYL-I 646
                 G+    N  L   Q           EK     Y C  C K+F   + L  H+  +
Sbjct: 995  ECNECGKAFAQNSTLRVHQR------IHTGEKP----YECDECGKTFVRKAALRVHHTRM 1044

Query: 647  HAGQKPFECSVCGKT 661
            H  +K   C+  GK+
Sbjct: 1045 HTREKTLACNGFGKS 1059



 Score =  157 bits (398), Expect = 2e-38
 Identities = 133/530 (25%), Positives = 224/530 (42%), Gaps = 85/530 (16%)

Query: 25   RPYVCNICFKHFETPSKLARHYLIHTGQKPFECDVCHKTFRQLVHLERHQLTHS--LPFK 82
            +PY CN C K F   S L  H  IHTG+KP+EC  C KTF     L  H   H+   P++
Sbjct: 572  KPYECNDCGKSFTYNSALRAHQRIHTGEKPYECSDCEKTFAHNSALRAHHRIHTGEKPYE 631

Query: 83   CSICQRHFKNLKTFVKHQQLH--------NE-----TYQNNVKQVRRLLEAKQEKSMYGV 129
            C+ C R F ++     HQ++H        NE     TY + ++  +R+   ++       
Sbjct: 632  CNECGRSFAHISVLKAHQRIHTGEKPYECNECGRSFTYNSALRAHQRIHTGRKPYECSDC 691

Query: 130  YNTF-------------TTEERWALHPCSKSDPMYS-MKRRKNIHA------CTICGKMF 169
              TF             T E+ +  + C K+    S ++  +NIH       C+ CGK F
Sbjct: 692  EKTFAHNSALKIHQRIHTGEKPYECNECEKTFAHNSALRAHQNIHTGEKLYECSECGKTF 751

Query: 170  PSQSKLDRHVLIHTGQRPFKCVLCTKSFRQSTHLKIHQLTHSEERPFQCCFCQKGFKIQS 229
              +++L  H  IHTG++P++C  C K+F Q ++L  H+  H+ E+P++C  C K F  ++
Sbjct: 752  FQKTRLSTHRRIHTGEKPYECSKCGKTFSQKSYLSGHERIHTGEKPYECNVCGKTFVYKA 811

Query: 230  KLLKHKQIHTRNKAFRALLLKKRRTESRPL--PNKLNANQGGFENGEIGES-EENNPLDV 286
             L+ H++IHT  K +      K  ++   L    +++  +  +E  E G++  +N+ L  
Sbjct: 812  ALIVHQRIHTGEKPYECNQCGKTFSQRTHLCAHQRIHTGEKPYECNECGKTFADNSALRA 871

Query: 287  HSIYIV---PFQCPKCEKCFESEQILNEHSCFAARSGKIPSRFKRSYNYKTIVKKILAKL 343
            H        P++C  C K F     L  H     RSG+ P  ++ S   KT  +K     
Sbjct: 872  HHRIHTGEKPYECNDCGKTFSKTSHLRAH--LRTRSGEKP--YECSECGKTFSEK----- 922

Query: 344  KRARSKKLDNFQSEKKVFKKSFLRNCDLISGEQSSEQTQRTFVGSLGKHGTYKTIGNRKK 403
                        + ++V        C++     +   T R                +++ 
Sbjct: 923  --------SYVSAHQRVHTGEKPYECNVCGKPFAHNSTLRV---------------HQRI 959

Query: 404  KTLTLPFSWQNMGKNLKGILTTENILSIDNSVNKKDLSI-CGSSGEEFFNNCEVLQCGFS 462
             T    +   + GK      + ++ LS    ++  +    C   G+ F  N  +      
Sbjct: 960  HTGEKSYECNDCGKT----FSQKSHLSAHQRIHTGEKPYECNECGKAFAQNSTLR----- 1010

Query: 463  VPRENIRTRHKICPCDKCEKVFPSISKLKRHYL-IHTGQRPFGCNICGKS 511
               + I T  K   CD+C K F   + L+ H+  +HT ++   CN  GKS
Sbjct: 1011 -VHQRIHTGEKPYECDECGKTFVRKAALRVHHTRMHTREKTLACNGFGKS 1059



 Score = 46.2 bits (108), Expect = 1e-04
 Identities = 50/238 (21%), Positives = 77/238 (32%), Gaps = 67/238 (28%)

Query: 498 TGQRPFGCNICGKSFRQ-SAHLKRHEQTHNEKSPYASLCQVEFGNFNNLSNHSGNNVNYN 556
           TG   F  N C ++F Q SAH+   +    +K          FG  N  ++     +++ 
Sbjct: 320 TGWSAFESNKCEENFSQSSAHIVHQKTQAGDK----------FGEHNECTDALYQKLDFT 369

Query: 557 ASQQCQAPGVQKYEVSESDQMSGVKAESQDFIPGSTGQPCLPNVLLESEQSNPFCSYSEH 616
           A Q+       K+ +S+           +  +                E +  FCS S  
Sbjct: 370 AHQRIHTE--DKFYLSDEHGKCRKSFYRKAHLIQHQRPHSGEKTYQYEECAKSFCSSSHP 427

Query: 617 QEKNDVF----LYRCSVCAKSFRSPSKLERHYLIHA------------------------ 648
            +    +    LY C+ C K+F   S L +H  IH                         
Sbjct: 428 IQHPGTYVGFKLYECNECGKAFCQNSNLSKHLRIHTKEKPCDNNGCGRSYKSPLIGHQKT 487

Query: 649 --------------------------GQKPFECSVCGKTFRQAPHWKRHQLTHFKERP 680
                                     G+KP+EC  CGKTF +  H + HQ  H  E+P
Sbjct: 488 DAEMELCGGSEYGKTSHLKGHQRILMGEKPYECIECGKTFSKTSHLRAHQRIHTGEKP 545


>gi|68303809 zinc finger protein 43 [Homo sapiens]
          Length = 809

 Score =  199 bits (506), Expect = 7e-51
 Identities = 174/694 (25%), Positives = 279/694 (40%), Gaps = 95/694 (13%)

Query: 14  QCVVANKLPRNRPYVCNICFKHFETPSKLARHYLIHTGQKPFECDVCHKTFRQLVHLERH 73
           QC+ A +   ++ ++ + C K F   S   RH + HT +K F+C  C K+F  L HL +H
Sbjct: 136 QCLPATQ---SKIFLFDKCVKAFHKFSNSNRHKISHTEKKLFKCKECGKSFCMLPHLAQH 192

Query: 74  QLTHSLP--FKCSICQRHFKNLKTFVKHQQLHNETYQNNVKQVRRLLEAKQEKSMYGVYN 131
           ++ H+     KC  C + F       KH++++        ++  ++              
Sbjct: 193 KIIHTRVNFCKCEKCGKAFNCPSIITKHKRINTGEKPYTCEECGKV-------------- 238

Query: 132 TFTTEERWALHPCSKSDPMYSMKRRKNIHACTICGKMFPSQSKLDRHVLIHTGQRPFKCV 191
            F    R   H  + +        R  ++ C  CGK F   S L  H +I TG++ +KC 
Sbjct: 239 -FNWSSRLTTHKKNYT--------RYKLYKCEECGKAFNKSSILTTHKIIRTGEKFYKCK 289

Query: 192 LCTKSFRQSTHLKIHQLTHSEERPFQCCFCQKGFKIQSKLLKHKQIHTRNKAFRALLLKK 251
            C K+F QS++L  H+  H  E+P++C  C K F   S L KHK+IHT  K +      K
Sbjct: 290 ECAKAFNQSSNLTEHKKIHPGEKPYKCEECGKAFNWPSTLTKHKRIHTGEKPYTCEECGK 349

Query: 252 RRTESRPLP--NKLNANQGGFENGEIGE--SEENNPLDVHSIYI--VPFQCPKCEKCFES 305
              +   L    +++  +  ++  E GE  S  +N      I+    P++C +C K F+ 
Sbjct: 350 AFNQFSNLTTHKRIHTAEKFYKCTECGEAFSRSSNLTKHKKIHTEKKPYKCEECGKAFKW 409

Query: 306 EQILNEHSCF-----------AARSGKIPSRFKRSYNYKTIVKKILAKLKRARSKKLDNF 354
              L EH                ++   PS   +     T  K    ++      +  N 
Sbjct: 410 SSKLTEHKLTHTGEKPYKCEECGKAFNWPSTLTKHNRIHTGEKPYKCEVCGKAFNQFSNL 469

Query: 355 QSEKKVFKKSFLRNCDLISGEQSSEQTQRTFVGSLGKHGTYKTIGNRKKKTLTLPFSWQN 414
            + K++        C     E+  +   R+   +L KH   K I   KK     P+  + 
Sbjct: 470 TTHKRIHTAEKPYKC-----EECGKAFSRS--SNLTKH---KKIHIEKK-----PYKCEE 514

Query: 415 MGKNLK--GILTTENILSIDNSVNKKDLSICGSSGEEFFNNCEVLQCGFSVPRENIRTRH 472
            GK  K    LT   I        K     CG +    FN+  +L        + I T  
Sbjct: 515 CGKAFKWSSKLTEHKITHTGEKPYK--CEECGKA----FNHFSIL-----TKHKRIHTGE 563

Query: 473 KICPCDKCEKVFPSISKLKRHYLIHTGQRPFGCNICGKSFRQSAHLKRHEQTHNEKSPY- 531
           K   C++C K F   S L  H  IHTG++ + C  CGK+F QS++L  H++ H    PY 
Sbjct: 564 KPYKCEECGKAFTQSSNLTTHKKIHTGEKFYKCEECGKAFTQSSNLTTHKKIHTGGKPYK 623

Query: 532 ASLCQVEFGNFNNLSNHSGNNVNYNASQQCQAPGVQKYEVSESDQMSGVKAESQDFIPGS 591
              C   F  F+ L+ H   +       +C+       E  ++ + S    + +    G 
Sbjct: 624 CEECGKAFNQFSTLTKHKIIHTE-EKPYKCE-------ECGKAFKWSSTLTKHKIIHTGE 675

Query: 592 TGQPCLPNVLLESEQSNPFCSYSEHQEKNDVF-----LYRCSVCAKSFRSPSKLERHYLI 646
               C        E+       S     + +       Y+C  C K+F   S L  H  I
Sbjct: 676 KPYKC--------EECGKAFKLSSTLSTHKIIHTGEKPYKCEKCGKAFNRSSNLIEHKKI 727

Query: 647 HAGQKPFECSVCGKTFRQAPHWKRHQLTHFKERP 680
           H G++P++C  CGK F  + H   H+  H KE+P
Sbjct: 728 HTGEQPYKCEECGKAFNYSSHLNTHKRIHTKEQP 761



 Score =  196 bits (498), Expect = 6e-50
 Identities = 154/571 (26%), Positives = 252/571 (44%), Gaps = 87/571 (15%)

Query: 23  RNRPYVCNICFKHFETPSKLARHYLIHTGQKPFECDVCHKTFRQLVHLERHQLTH--SLP 80
           R + Y C  C K F   S L  H +I TG+K ++C  C K F Q  +L  H+  H    P
Sbjct: 254 RYKLYKCEECGKAFNKSSILTTHKIIRTGEKFYKCKECAKAFNQSSNLTEHKKIHPGEKP 313

Query: 81  FKCSICQRHFKNLKTFVKHQQLHNETYQNNVKQVRRLLEAKQEKSMYGVYNTFTTEERWA 140
           +KC  C + F    T  KH+++H        ++  +          +  ++  TT +R  
Sbjct: 314 YKCEECGKAFNWPSTLTKHKRIHTGEKPYTCEECGKA---------FNQFSNLTTHKR-- 362

Query: 141 LHPCSKSDPMYSMKRRKNIHACTICGKMFPSQSKLDRHVLIHTGQRPFKCVLCTKSFRQS 200
           +H   K             + CT CG+ F   S L +H  IHT ++P+KC  C K+F+ S
Sbjct: 363 IHTAEK------------FYKCTECGEAFSRSSNLTKHKKIHTEKKPYKCEECGKAFKWS 410

Query: 201 THLKIHQLTHSEERPFQCCFCQKGFKIQSKLLKHKQIHTRNKAFRALLLKKRRTESRPLP 260
           + L  H+LTH+ E+P++C  C K F   S L KH +IHT  K ++  +  K   +   L 
Sbjct: 411 SKLTEHKLTHTGEKPYKCEECGKAFNWPSTLTKHNRIHTGEKPYKCEVCGKAFNQFSNLT 470

Query: 261 --NKLNANQGGFENGEIGE--SEENNPLDVHSIYI--VPFQCPKCEKCFESEQILNEHSC 314
              +++  +  ++  E G+  S  +N      I+I   P++C +C K F+    L EH  
Sbjct: 471 THKRIHTAEKPYKCEECGKAFSRSSNLTKHKKIHIEKKPYKCEECGKAFKWSSKLTEHK- 529

Query: 315 FAARSGKIPSRFK---RSYNYKTIV---KKILAKLKRARSKKL-------DNFQSEKKVF 361
               +G+ P + +   +++N+ +I+   K+I    K  + ++         N  + KK+ 
Sbjct: 530 -ITHTGEKPYKCEECGKAFNHFSILTKHKRIHTGEKPYKCEECGKAFTQSSNLTTHKKIH 588

Query: 362 KKSFLRNCDLI--SGEQSSEQTQRTFVGSLGKHGTYKTIGNRKKKTLTL----------- 408
                  C+    +  QSS  T    + + GK    +  G    +  TL           
Sbjct: 589 TGEKFYKCEECGKAFTQSSNLTTHKKIHTGGKPYKCEECGKAFNQFSTLTKHKIIHTEEK 648

Query: 409 PFSWQNMGKNLK--GILTTENILSIDNSVNKKDLSICGSSGEEFFNNCEVLQCGFSVPRE 466
           P+  +  GK  K    LT   I+                +GE+ +  CE  +CG +    
Sbjct: 649 PYKCEECGKAFKWSSTLTKHKII---------------HTGEKPY-KCE--ECGKAFKLS 690

Query: 467 NIRTRHKIC-------PCDKCEKVFPSISKLKRHYLIHTGQRPFGCNICGKSFRQSAHLK 519
           +  + HKI         C+KC K F   S L  H  IHTG++P+ C  CGK+F  S+HL 
Sbjct: 691 STLSTHKIIHTGEKPYKCEKCGKAFNRSSNLIEHKKIHTGEQPYKCEECGKAFNYSSHLN 750

Query: 520 RHEQTHNEKSPY-ASLCQVEFGNFNNLSNHS 549
            H++ H ++ PY    C   F  ++NL+ H+
Sbjct: 751 THKRIHTKEQPYKCKECGKAFNQYSNLTTHN 781



 Score =  182 bits (461), Expect = 1e-45
 Identities = 142/538 (26%), Positives = 225/538 (41%), Gaps = 84/538 (15%)

Query: 22  PRNRPYVCNICFKHFETPSKLARHYLIHTGQKPFECDVCHKTFRQLVHLERHQLTHSLP- 80
           P  +PY C  C K F  PS L +H  IHTG+KP+ C+ C K F Q  +L  H+  H+   
Sbjct: 309 PGEKPYKCEECGKAFNWPSTLTKHKRIHTGEKPYTCEECGKAFNQFSNLTTHKRIHTAEK 368

Query: 81  -FKCSICQRHFKNLKTFVKHQQLHNETYQNNVKQVRRLLEAKQEKSMYGVYNTFTTEERW 139
            +KC+ C   F       KH+++H E      ++  +  +   + + + +  T T E+ +
Sbjct: 369 FYKCTECGEAFSRSSNLTKHKKIHTEKKPYKCEECGKAFKWSSKLTEHKL--THTGEKPY 426

Query: 140 ALHPCSKSDPMYSMKRRKN-IHA------CTICGKMFPSQSKLDRHVLIHTGQRPFKCVL 192
               C K+    S   + N IH       C +CGK F   S L  H  IHT ++P+KC  
Sbjct: 427 KCEECGKAFNWPSTLTKHNRIHTGEKPYKCEVCGKAFNQFSNLTTHKRIHTAEKPYKCEE 486

Query: 193 CTKSFRQSTHLKIHQLTHSEERPFQCCFCQKGFKIQSKLLKHKQIHTRNKAFR------- 245
           C K+F +S++L  H+  H E++P++C  C K FK  SKL +HK  HT  K ++       
Sbjct: 487 CGKAFSRSSNLTKHKKIHIEKKPYKCEECGKAFKWSSKLTEHKITHTGEKPYKCEECGKA 546

Query: 246 ----ALLLKKRRTESRPLPNKLNANQGGFENGEIGESEENNPLDVHSIYIVP--FQCPKC 299
               ++L K +R  +   P K       F       ++ +N      I+     ++C +C
Sbjct: 547 FNHFSILTKHKRIHTGEKPYKCEECGKAF-------TQSSNLTTHKKIHTGEKFYKCEEC 599

Query: 300 EKCFESEQILNEHSCF--AARSGKIPSRFKRSYNYKTIVKKILAKLKRARSKKLDNFQSE 357
            K F     L  H       +  K     K    + T+ K  +               +E
Sbjct: 600 GKAFTQSSNLTTHKKIHTGGKPYKCEECGKAFNQFSTLTKHKI-------------IHTE 646

Query: 358 KKVFKKSFLRNCDLISGEQSSEQTQRTFVGS--LGKHGTYKTIGNRKKKTLTLPFSWQNM 415
           +K +K                E+  + F  S  L KH   K I   +K     P+  +  
Sbjct: 647 EKPYK---------------CEECGKAFKWSSTLTKH---KIIHTGEK-----PYKCEEC 683

Query: 416 GK--NLKGILTTENILSIDNSVNKKDLSICGSSGEEFFNNCEVLQCGFSVPRENIRTRHK 473
           GK   L   L+T  I+       K     C   G+ F  +  +++       + I T  +
Sbjct: 684 GKAFKLSSTLSTHKIIHTGEKPYK-----CEKCGKAFNRSSNLIE------HKKIHTGEQ 732

Query: 474 ICPCDKCEKVFPSISKLKRHYLIHTGQRPFGCNICGKSFRQSAHLKRHEQTHNEKSPY 531
              C++C K F   S L  H  IHT ++P+ C  CGK+F Q ++L  H + H  +  Y
Sbjct: 733 PYKCEECGKAFNYSSHLNTHKRIHTKEQPYKCKECGKAFNQYSNLTTHNKIHTGEKLY 790



 Score =  155 bits (393), Expect = 9e-38
 Identities = 155/655 (23%), Positives = 252/655 (38%), Gaps = 115/655 (17%)

Query: 50  TGQKPFECDVCHKTFRQLVHLERHQLTHSLP--FKCSICQRHFKNLKTFVKHQQLHNETY 107
           T  K F  D C K F +  +  RH+++H+    FKC  C + F  L    +H+ +H    
Sbjct: 141 TQSKIFLFDKCVKAFHKFSNSNRHKISHTEKKLFKCKECGKSFCMLPHLAQHKIIHTRV- 199

Query: 108 QNNVKQVRRLLEAKQEKSMYGVYNTFTTEERWALHPCSKSDPMYSMKRRKNIHACTICGK 167
             N  +  +  +A    S+   +    T E+                     + C  CGK
Sbjct: 200 --NFCKCEKCGKAFNCPSIITKHKRINTGEK--------------------PYTCEECGK 237

Query: 168 MFPSQSKLDRHVLIHTGQRPFKCVLCTKSFRQSTHLKIHQLTHSEERPFQCCFCQKGFKI 227
           +F   S+L  H   +T  + +KC  C K+F +S+ L  H++  + E+ ++C  C K F  
Sbjct: 238 VFNWSSRLTTHKKNYTRYKLYKCEECGKAFNKSSILTTHKIIRTGEKFYKCKECAKAFNQ 297

Query: 228 QSKLLKHKQIHTRNKAFRALLLKKRRTESRPLPNKLNANQGGFENGEIGESEENNPLDVH 287
            S L +HK+IH   K ++     +   ++   P+ L  ++     GE             
Sbjct: 298 SSNLTEHKKIHPGEKPYKC----EECGKAFNWPSTLTKHKR-IHTGE------------- 339

Query: 288 SIYIVPFQCPKCEKCFESEQILNEHSCFAARSGKIPSRFKRSYNYKTIVKKILAKLKRAR 347
                P+ C +C K F     L  H              KR +  +   K        +R
Sbjct: 340 ----KPYTCEECGKAFNQFSNLTTH--------------KRIHTAEKFYKCTECGEAFSR 381

Query: 348 SKKLDNFQ---SEKKVFKKSFLRNCDLISGEQSSEQTQRTFVGSLGKHGTYKTIGNRKKK 404
           S  L   +   +EKK +K                E+  + F  S       K   ++   
Sbjct: 382 SSNLTKHKKIHTEKKPYK---------------CEECGKAFKWSS------KLTEHKLTH 420

Query: 405 TLTLPFSWQNMGK--NLKGILTTENILSIDNSVNKKDLSICGSSGEEFFNNCEVLQCGFS 462
           T   P+  +  GK  N    LT  N +       K +  +CG +  +F N          
Sbjct: 421 TGEKPYKCEECGKAFNWPSTLTKHNRIHTGEKPYKCE--VCGKAFNQFSN---------L 469

Query: 463 VPRENIRTRHKICPCDKCEKVFPSISKLKRHYLIHTGQRPFGCNICGKSFRQSAHLKRHE 522
              + I T  K   C++C K F   S L +H  IH  ++P+ C  CGK+F+ S+ L  H+
Sbjct: 470 TTHKRIHTAEKPYKCEECGKAFSRSSNLTKHKKIHIEKKPYKCEECGKAFKWSSKLTEHK 529

Query: 523 QTHNEKSPY-ASLCQVEFGNFNNLSNHSGNNVNYNASQQCQAPGVQKYEVSESDQMSGVK 581
            TH  + PY    C   F +F+ L+ H   +       +C+  G  K     S+  +  K
Sbjct: 530 ITHTGEKPYKCEECGKAFNHFSILTKHKRIHTG-EKPYKCEECG--KAFTQSSNLTTHKK 586

Query: 582 AESQDFIPGSTGQPCLPNVLLESEQSNPFCSYSEHQEKNDVFLYRCSVCAKSFRSPSKLE 641
             +     G     C       ++ SN       H        Y+C  C K+F   S L 
Sbjct: 587 IHT-----GEKFYKCEECGKAFTQSSNLTTHKKIHTGGKP---YKCEECGKAFNQFSTLT 638

Query: 642 RHYLIHAGQKPFECSVCGKTFRQAPHWKRHQLTHFKERPQ-----GKVVALDSVM 691
           +H +IH  +KP++C  CGK F+ +    +H++ H  E+P      GK   L S +
Sbjct: 639 KHKIIHTEEKPYKCEECGKAFKWSSTLTKHKIIHTGEKPYKCEECGKAFKLSSTL 693



 Score =  142 bits (358), Expect = 1e-33
 Identities = 76/230 (33%), Positives = 115/230 (50%), Gaps = 11/230 (4%)

Query: 25  RPYVCNICFKHFETPSKLARHYLIHTGQKPFECDVCHKTFRQLVHLERHQLTHS--LPFK 82
           +PY C  C K F   S L  H  IHTG+K ++C+ C K F Q  +L  H+  H+   P+K
Sbjct: 564 KPYKCEECGKAFTQSSNLTTHKKIHTGEKFYKCEECGKAFTQSSNLTTHKKIHTGGKPYK 623

Query: 83  CSICQRHFKNLKTFVKHQQLHNETYQNNVKQVRRLLEAKQEKSMYGVYNTFTTEERWALH 142
           C  C + F    T  KH+ +H E      ++  +  +     + + + +T   E+ +   
Sbjct: 624 CEECGKAFNQFSTLTKHKIIHTEEKPYKCEECGKAFKWSSTLTKHKIIHT--GEKPYKCE 681

Query: 143 PCSKSDPMYS-MKRRKNIHA------CTICGKMFPSQSKLDRHVLIHTGQRPFKCVLCTK 195
            C K+  + S +   K IH       C  CGK F   S L  H  IHTG++P+KC  C K
Sbjct: 682 ECGKAFKLSSTLSTHKIIHTGEKPYKCEKCGKAFNRSSNLIEHKKIHTGEQPYKCEECGK 741

Query: 196 SFRQSTHLKIHQLTHSEERPFQCCFCQKGFKIQSKLLKHKQIHTRNKAFR 245
           +F  S+HL  H+  H++E+P++C  C K F   S L  H +IHT  K ++
Sbjct: 742 AFNYSSHLNTHKRIHTKEQPYKCKECGKAFNQYSNLTTHNKIHTGEKLYK 791



 Score = 85.9 bits (211), Expect = 1e-16
 Identities = 65/251 (25%), Positives = 105/251 (41%), Gaps = 27/251 (10%)

Query: 452 NNCEVLQCGFSVPRENI-RTRHKICPCDKCEKVFPSISKLKRHYLIHTGQRPFGCNICGK 510
           + C+V + G++   + +  T+ KI   DKC K F   S   RH + HT ++ F C  CGK
Sbjct: 122 DECKVHRGGYNGFNQCLPATQSKIFLFDKCVKAFHKFSNSNRHKISHTEKKLFKCKECGK 181

Query: 511 SFRQSAHLKRHEQTHN-------EKSPYASLC--------QVEFGNFNNLSNHSGNNVNY 555
           SF    HL +H+  H        EK   A  C        ++  G         G   N+
Sbjct: 182 SFCMLPHLAQHKIIHTRVNFCKCEKCGKAFNCPSIITKHKRINTGEKPYTCEECGKVFNW 241

Query: 556 NASQQCQAPGVQKYEVSESDQ------MSGVKAESQDFIPGSTGQPCLPNVLLESEQSNP 609
           ++          +Y++ + ++       S +    +    G     C       ++ SN 
Sbjct: 242 SSRLTTHKKNYTRYKLYKCEECGKAFNKSSILTTHKIIRTGEKFYKCKECAKAFNQSSN- 300

Query: 610 FCSYSEHQEKN-DVFLYRCSVCAKSFRSPSKLERHYLIHAGQKPFECSVCGKTFRQAPHW 668
               +EH++ +     Y+C  C K+F  PS L +H  IH G+KP+ C  CGK F Q  + 
Sbjct: 301 ---LTEHKKIHPGEKPYKCEECGKAFNWPSTLTKHKRIHTGEKPYTCEECGKAFNQFSNL 357

Query: 669 KRHQLTHFKER 679
             H+  H  E+
Sbjct: 358 TTHKRIHTAEK 368



 Score = 33.1 bits (74), Expect = 0.88
 Identities = 14/34 (41%), Positives = 19/34 (55%)

Query: 23  RNRPYVCNICFKHFETPSKLARHYLIHTGQKPFE 56
           + +PY C  C K F   S L  H  IHTG+K ++
Sbjct: 758 KEQPYKCKECGKAFNQYSNLTTHNKIHTGEKLYK 791


>gi|14211907 zinc finger protein 347 [Homo sapiens]
          Length = 839

 Score =  199 bits (506), Expect = 7e-51
 Identities = 145/539 (26%), Positives = 235/539 (43%), Gaps = 53/539 (9%)

Query: 23  RNRPYVCNICFKHFETPSKLARHYLIHTGQKPFECDVCHKTFRQLVHLERHQLTHS--LP 80
           + +PY C  C K F T S L  H +IHTG+K ++C+ C K F +   L +HQ  H+   P
Sbjct: 285 KEKPYKCYECGKAFRTRSNLTTHQVIHTGEKRYKCNECGKVFSRNSQLSQHQKIHTGEKP 344

Query: 81  FKCSICQRHFKNLKTFVKHQQLHNETYQNNVKQVRRLLEAKQEKSMYGVYNTFTTEERWA 140
           +KC+ C + F      V+H+ +H         +  +   A+   +++    T + E+ + 
Sbjct: 345 YKCNECGKVFTQNSHLVRHRGIHTGEKPYKCNECGKAFRARSSLAIHQA--THSGEKPYK 402

Query: 141 LHPCSKSDPMYS-MKRRKNIHA------CTICGKMFPSQSKLDRHVLIHTGQRPFKCVLC 193
            + C K     S +     IH       C  CGK F  +S L  H++IHTG++P+KC  C
Sbjct: 403 CNECGKVFTQNSHLTNHWRIHTGEKPYKCNECGKAFGVRSSLAIHLVIHTGEKPYKCHEC 462

Query: 194 TKSFRQSTHLKIHQLTHSEERPFQCCFCQKGFKIQSKLLKHKQIHTRNKAFRALLLKKRR 253
            K FR+++HL  HQL H+ E+P++C  C K F+  S L  H+ IHT  K ++     K  
Sbjct: 463 GKVFRRNSHLARHQLIHTGEKPYKCNECGKAFRAHSNLTTHQVIHTGEKPYKCNECGKVF 522

Query: 254 TESRPLPNKLNANQGGFENGEIGESEENNPLDVHSIYIVPFQCPKCEKCFESEQILNEHS 313
           T++  L N    + G                      + P+ C +C K F     L  H 
Sbjct: 523 TQNSHLANHQRIHTG----------------------VKPYMCNECGKAFSVYSSLTTHQ 560

Query: 314 CFAARSGKIPSRFKRSYNYKTIVKKILAKLKRARSKKLDNFQSEKKVFK-KSFL-RNCDL 371
                +G+ P +        T    +         +K        KVF+  S+L R+  +
Sbjct: 561 VI--HTGEKPYKCNECGKVFTQNSHLARHRGIHTGEKPYKCNECGKVFRHNSYLSRHQRI 618

Query: 372 ISGEQSSEQTQRTFVGSLGKHGTYKTIGNRKKKTLTLPFSWQNMGKNLKGILTTENILSI 431
            +GE+  +  +  +  +  +H    T  ++   T   P+     GK    + T  + L+ 
Sbjct: 619 HTGEKPYKYNE--YGKAFSEHSNLTT--HQVIHTGEKPYKCNECGK----VFTQNSHLAR 670

Query: 432 DNSVNKKDLSI-CGSSGEEFFNNCEVLQCGFSVPRENIRTRHKICPCDKCEKVFPSISKL 490
              V+       C   G+ F    ++ +       + + T  K   C++C K F   S L
Sbjct: 671 HRRVHTGGKPYQCNECGKAFSQTSKLAR------HQRVHTGEKPYECNQCGKAFSVRSSL 724

Query: 491 KRHYLIHTGQRPFGCNICGKSFRQSAHLKRHEQTHNEKSPY-ASLCQVEFGNFNNLSNH 548
             H  IHTG++P+ CN CGK F Q++HL RH   H  + PY  + C   F   + L+ H
Sbjct: 725 TTHQAIHTGKKPYKCNECGKVFTQNSHLARHRGIHTGEKPYKCNECGKAFSQTSKLARH 783



 Score =  193 bits (491), Expect = 4e-49
 Identities = 173/657 (26%), Positives = 258/657 (39%), Gaps = 134/657 (20%)

Query: 47  LIHTGQK------PFECDVCHKTFRQLVHLERHQLTHSL--PFKCSICQRHFKNLKTFVK 98
           L+  GQK      P++ D C   F Q  HL  HQ +H+   P+KC  C + F+       
Sbjct: 247 LLTQGQKANNWGSPYKSDGCGMVFPQNSHLASHQRSHTKEKPYKCYECGKAFRTRSNLTT 306

Query: 99  HQQLHNETYQNNVKQVRRLLEAKQEKSMYGVYNTFTTEERWALHPCSKSDPMYS-MKRRK 157
           HQ +H                              T E+R+  + C K     S + + +
Sbjct: 307 HQVIH------------------------------TGEKRYKCNECGKVFSRNSQLSQHQ 336

Query: 158 NIHA------CTICGKMFPSQSKLDRHVLIHTGQRPFKCVLCTKSFRQSTHLKIHQLTHS 211
            IH       C  CGK+F   S L RH  IHTG++P+KC  C K+FR  + L IHQ THS
Sbjct: 337 KIHTGEKPYKCNECGKVFTQNSHLVRHRGIHTGEKPYKCNECGKAFRARSSLAIHQATHS 396

Query: 212 EERPFQCCFCQKGFKIQSKLLKHKQIHTRNKAFRALLLKKRRTESRPLPNKLNANQGG-- 269
            E+P++C  C K F   S L  H +IHT  K ++     K       L   L  + G   
Sbjct: 397 GEKPYKCNECGKVFTQNSHLTNHWRIHTGEKPYKCNECGKAFGVRSSLAIHLVIHTGEKP 456

Query: 270 FENGEIGES-EENNPLDVHSIYIV---PFQCPKCEKCFESEQILNEHSCFAARSGKIPSR 325
           ++  E G+    N+ L  H +      P++C +C K F +   L  H      +G+ P +
Sbjct: 457 YKCHECGKVFRRNSHLARHQLIHTGEKPYKCNECGKAFRAHSNLTTHQVI--HTGEKPYK 514

Query: 326 FKRSYNYKTIVKKILAKLKRARSKKLDNFQSEKKVFKKSFLRNCDLISGEQSSEQTQRTF 385
                   T            ++  L N Q      K      C    G+  S  +  T 
Sbjct: 515 CNECGKVFT------------QNSHLANHQRIHTGVKPYMCNEC----GKAFSVYSSLT- 557

Query: 386 VGSLGKHGTYKTIGNRKKKTLTLPFSWQNMGKNLKGILTTENILSIDNSVNKKDLSI-CG 444
                   T++ I   +K     P+     GK    + T  + L+    ++  +    C 
Sbjct: 558 --------THQVIHTGEK-----PYKCNECGK----VFTQNSHLARHRGIHTGEKPYKCN 600

Query: 445 SSGEEFFNNCEVLQCGFSVPRENIRTRHKICPCDKCEKVFPSISKLKRHYLIHTGQRPFG 504
             G+ F +N  + +       + I T  K    ++  K F   S L  H +IHTG++P+ 
Sbjct: 601 ECGKVFRHNSYLSR------HQRIHTGEKPYKYNEYGKAFSEHSNLTTHQVIHTGEKPYK 654

Query: 505 CNICGKSFRQSAHLKRHEQTHNEKSPY-ASLCQVEFGNFNNLSNHSGNNVNYNASQQCQA 563
           CN CGK F Q++HL RH + H    PY  + C   F   + L+ H           Q   
Sbjct: 655 CNECGKVFTQNSHLARHRRVHTGGKPYQCNECGKAFSQTSKLARH-----------QRVH 703

Query: 564 PGVQKYEVSESDQMSGVKAESQDFIPGSTGQPCLPNVLLESEQSNPFCSYSEHQEKNDVF 623
            G + YE ++  +   V++         TG+                             
Sbjct: 704 TGEKPYECNQCGKAFSVRSSLTTHQAIHTGKKP--------------------------- 736

Query: 624 LYRCSVCAKSFRSPSKLERHYLIHAGQKPFECSVCGKTFRQAPHWKRHQLTHFKERP 680
            Y+C+ C K F   S L RH  IH G+KP++C+ CGK F Q     RHQ  H  E+P
Sbjct: 737 -YKCNECGKVFTQNSHLARHRGIHTGEKPYKCNECGKAFSQTSKLARHQRIHTGEKP 792



 Score =  185 bits (469), Expect = 1e-46
 Identities = 164/674 (24%), Positives = 260/674 (38%), Gaps = 153/674 (22%)

Query: 26  PYVCNICFKHFETPSKLARHYLIHTGQKPFECDVCHKTFRQLVHLERHQLTHS------- 78
           PY  + C   F   S LA H   HT +KP++C  C K FR   +L  HQ+ H+       
Sbjct: 260 PYKSDGCGMVFPQNSHLASHQRSHTKEKPYKCYECGKAFRTRSNLTTHQVIHTGEKRYKC 319

Query: 79  -----------------------LPFKCSICQRHFKNLKTFVKHQQLHNETYQNNVKQVR 115
                                   P+KC+ C + F      V+H+ +H         +  
Sbjct: 320 NECGKVFSRNSQLSQHQKIHTGEKPYKCNECGKVFTQNSHLVRHRGIHTGEKPYKCNECG 379

Query: 116 RLLEAKQEKSMYGVYNTFTTEERWALHPCSKSDPMYS-MKRRKNIHA------CTICGKM 168
           +   A+   +++    T + E+ +  + C K     S +     IH       C  CGK 
Sbjct: 380 KAFRARSSLAIHQA--THSGEKPYKCNECGKVFTQNSHLTNHWRIHTGEKPYKCNECGKA 437

Query: 169 FPSQSKLDRHVLIHTGQRPFKCVLCTKSFRQSTHLKIHQLTHSEERPFQCCFCQKGFKIQ 228
           F  +S L  H++IHTG++P+KC  C K FR+++HL  HQL H+ E+P++C  C K F+  
Sbjct: 438 FGVRSSLAIHLVIHTGEKPYKCHECGKVFRRNSHLARHQLIHTGEKPYKCNECGKAFRAH 497

Query: 229 SKLLKHKQIHTRNKAFRALLLKKRRTESRPLPNKLNANQGGFENGEIGESEENNPLDVHS 288
           S L  H+ IHT  K ++     K  T++  L N    + G                    
Sbjct: 498 SNLTTHQVIHTGEKPYKCNECGKVFTQNSHLANHQRIHTG-------------------- 537

Query: 289 IYIVPFQCPKCEKCFESEQILNEHSCFAARSGKIPSRFKRSYNYKTIVKKILAKLKRARS 348
             + P+ C +C K F     L  H      +G+ P +                       
Sbjct: 538 --VKPYMCNECGKAFSVYSSLTTHQ--VIHTGEKPYKCNEC------------------- 574

Query: 349 KKLDNFQSEKKVFKKS--FLRNCDLISGEQSSEQTQRTFVGSLGKHGTYKTIGNRKKKTL 406
                     KVF ++    R+  + +GE+  +  +    G + +H +Y +  +++  T 
Sbjct: 575 ---------GKVFTQNSHLARHRGIHTGEKPYKCNE---CGKVFRHNSYLS-RHQRIHTG 621

Query: 407 TLPFSWQNMGKNLK--GILTTENILSIDNSVNKKDLSICGSSGEEFFNNCEVLQCGFSVP 464
             P+ +   GK       LTT  ++       K     C   G+ F  N  + +      
Sbjct: 622 EKPYKYNEYGKAFSEHSNLTTHQVIHTGEKPYK-----CNECGKVFTQNSHLAR------ 670

Query: 465 RENIRTRHKICPCDKCEKVFPSISKLKRHYLIHTGQRPFGCNICGKSFRQSAHLKRHEQT 524
              + T  K   C++C K F   SKL RH  +HTG++P+ CN CGK+F   + L  H+  
Sbjct: 671 HRRVHTGGKPYQCNECGKAFSQTSKLARHQRVHTGEKPYECNQCGKAFSVRSSLTTHQAI 730

Query: 525 HNEKSPY-ASLCQVEFGNFNNLSNHSGNNVNYNASQQCQAPGVQKYEVSESDQMSGVKAE 583
           H  K PY  + C   F   ++L+ H G +            G + Y+ +E       KA 
Sbjct: 731 HTGKKPYKCNECGKVFTQNSHLARHRGIHT-----------GEKPYKCNECG-----KAF 774

Query: 584 SQDFIPGSTGQPCLPNVLLESEQSNPFCSYSEHQEKNDVFLYRCSVCAKSFRSPSKLERH 643
           SQ                            + HQ  +     +   C K F   S L  H
Sbjct: 775 SQT------------------------SKLARHQRIHTG--EKPYECGKPFSICSSLTTH 808

Query: 644 YLIHAGQKPFECSV 657
             IH G KP++C+V
Sbjct: 809 QTIHTGGKPYKCNV 822



 Score =  171 bits (434), Expect = 2e-42
 Identities = 140/523 (26%), Positives = 207/523 (39%), Gaps = 83/523 (15%)

Query: 25  RPYVCNICFKHFETPSKLARHYLIHTGQKPFECDVCHKTFRQLVHLERHQLTHS--LPFK 82
           +PY CN C K F   S L RH  IHTG+KP++C+ C K FR    L  HQ THS   P+K
Sbjct: 343 KPYKCNECGKVFTQNSHLVRHRGIHTGEKPYKCNECGKAFRARSSLAIHQATHSGEKPYK 402

Query: 83  CSICQRHFKNLKTFVKHQQLHNETYQNNVKQVRRLLEAKQEKSMYGVYNTFTTEERWALH 142
           C+ C + F        H ++H         +  +    +   +++ V +T   E+ +  H
Sbjct: 403 CNECGKVFTQNSHLTNHWRIHTGEKPYKCNECGKAFGVRSSLAIHLVIHT--GEKPYKCH 460

Query: 143 PCSKSDPMYS-MKRRKNIHA------CTICGKMFPSQSKLDRHVLIHTGQRPFKCVLCTK 195
            C K     S + R + IH       C  CGK F + S L  H +IHTG++P+KC  C K
Sbjct: 461 ECGKVFRRNSHLARHQLIHTGEKPYKCNECGKAFRAHSNLTTHQVIHTGEKPYKCNECGK 520

Query: 196 SFRQSTHLKIHQLTHSEERPFQCCFCQKGFKIQSKLLKHKQIHTRNKAFRALLLKKRRTE 255
            F Q++HL  HQ  H+  +P+ C  C K F + S L  H+ IHT  K ++     K  T+
Sbjct: 521 VFTQNSHLANHQRIHTGVKPYMCNECGKAFSVYSSLTTHQVIHTGEKPYKCNECGKVFTQ 580

Query: 256 SRPLPNKLNANQGGFENGEIGESEENNPLDVHSIYIVPFQCPKCEKCFESEQILNEHSCF 315
           +  L     A   G   GE                  P++C +C K F     L+ H   
Sbjct: 581 NSHL-----ARHRGIHTGE-----------------KPYKCNECGKVFRHNSYLSRHQ-- 616

Query: 316 AARSGKIPSRFKRSYNYKTIVKKILAKLKRARSKKLDNFQSEKKVFK--KSFLRNCDLIS 373
              +G+ P      Y Y    K           + +   +   K  +  K F +N  L  
Sbjct: 617 RIHTGEKP------YKYNEYGKAFSEHSNLTTHQVIHTGEKPYKCNECGKVFTQNSHLAR 670

Query: 374 GEQSSEQTQRTFVGSLGK--HGTYKTIGNRKKKTLTLPFSWQNMGK--NLKGILTTENIL 429
             +     +       GK    T K   +++  T   P+     GK  +++  LTT   +
Sbjct: 671 HRRVHTGGKPYQCNECGKAFSQTSKLARHQRVHTGEKPYECNQCGKAFSVRSSLTTHQAI 730

Query: 430 SIDNSVNKKDLSICGSSGEEFFNNCEVLQCGFSVPRENIRTRHKICPCDKCEKVFPSISK 489
                  K     C   G+ F  N  + +         I T  K   C++C K F   SK
Sbjct: 731 HTGKKPYK-----CNECGKVFTQNSHLAR------HRGIHTGEKPYKCNECGKAFSQTSK 779

Query: 490 LKRHYLIHTGQR-------------------------PFGCNI 507
           L RH  IHTG++                         P+ CN+
Sbjct: 780 LARHQRIHTGEKPYECGKPFSICSSLTTHQTIHTGGKPYKCNV 822



 Score =  138 bits (347), Expect = 2e-32
 Identities = 80/243 (32%), Positives = 121/243 (49%), Gaps = 28/243 (11%)

Query: 25  RPYVCNICFKHFETPSKLARHYLIHTGQKPFECDVCHKTFRQLVHLERHQLTHS--LPFK 82
           +PY  N   K F   S L  H +IHTG+KP++C+ C K F Q  HL RH+  H+   P++
Sbjct: 623 KPYKYNEYGKAFSEHSNLTTHQVIHTGEKPYKCNECGKVFTQNSHLARHRRVHTGGKPYQ 682

Query: 83  CSICQRHFKNLKTFVKHQQLHNETYQNNVKQVRRLLEAKQEKSMYGVYNTFTTEERWALH 142
           C+ C + F       +HQ++H            +  E  Q    + V ++ TT +  A+H
Sbjct: 683 CNECGKAFSQTSKLARHQRVHTG---------EKPYECNQCGKAFSVRSSLTTHQ--AIH 731

Query: 143 PCSKSDPMYSMKRRKNIHACTICGKMFPSQSKLDRHVLIHTGQRPFKCVLCTKSFRQSTH 202
              K             + C  CGK+F   S L RH  IHTG++P+KC  C K+F Q++ 
Sbjct: 732 TGKKP------------YKCNECGKVFTQNSHLARHRGIHTGEKPYKCNECGKAFSQTSK 779

Query: 203 LKIHQLTHSEERPFQCCFCQKGFKIQSKLLKHKQIHTRNKAFRALLLKKRRTESRPLPNK 262
           L  HQ  H+ E+P++   C K F I S L  H+ IHT  K ++  + K  ++E +P    
Sbjct: 780 LARHQRIHTGEKPYE---CGKPFSICSSLTTHQTIHTGGKPYKCNVWKVLKSEFKPCKPS 836

Query: 263 LNA 265
            N+
Sbjct: 837 QNS 839



 Score =  122 bits (305), Expect = 1e-27
 Identities = 101/389 (25%), Positives = 167/389 (42%), Gaps = 70/389 (17%)

Query: 335 IVKKILAKLKRARSKKLDNFQSEKKVFK-----KSFLRNCDLISGEQS--------SEQT 381
           ++K  L    ++   +L  FQ E K+++     KSF  N  +   +Q         S++ 
Sbjct: 179 LIKNQLGLSLQSHLPELQLFQYEGKIYECNQVEKSFNNNSSVSPPQQMPYNVKTHISKKY 238

Query: 382 QRTFVGSL----GKHGT-----YKTIG-------------NRKKKTLTLPFSWQNMGK-- 417
            + F+ SL    G+        YK+ G             +++  T   P+     GK  
Sbjct: 239 LKDFISSLLLTQGQKANNWGSPYKSDGCGMVFPQNSHLASHQRSHTKEKPYKCYECGKAF 298

Query: 418 NLKGILTTENILSIDNSVNKKDLSICGSSGEEFFNNCEVLQCGFSVPRENIRTRHKICPC 477
             +  LTT  ++       K     C   G+ F  N ++ Q       + I T  K   C
Sbjct: 299 RTRSNLTTHQVIHTGEKRYK-----CNECGKVFSRNSQLSQ------HQKIHTGEKPYKC 347

Query: 478 DKCEKVFPSISKLKRHYLIHTGQRPFGCNICGKSFRQSAHLKRHEQTHNEKSPY-ASLCQ 536
           ++C KVF   S L RH  IHTG++P+ CN CGK+FR  + L  H+ TH+ + PY  + C 
Sbjct: 348 NECGKVFTQNSHLVRHRGIHTGEKPYKCNECGKAFRARSSLAIHQATHSGEKPYKCNECG 407

Query: 537 VEFGNFNNLSNHSGNNVNYNASQQCQAPGVQKYEVSESDQMSGVKAESQDFIPGSTGQPC 596
             F   ++L+NH   +            G + Y+ +E  +  GV++     +   TG+  
Sbjct: 408 KVFTQNSHLTNHWRIHT-----------GEKPYKCNECGKAFGVRSSLAIHLVIHTGEK- 455

Query: 597 LPNVLLESEQSNPFCSYSEHQEKNDVF-----LYRCSVCAKSFRSPSKLERHYLIHAGQK 651
                 +  +       + H  ++ +       Y+C+ C K+FR+ S L  H +IH G+K
Sbjct: 456 ----PYKCHECGKVFRRNSHLARHQLIHTGEKPYKCNECGKAFRAHSNLTTHQVIHTGEK 511

Query: 652 PFECSVCGKTFRQAPHWKRHQLTHFKERP 680
           P++C+ CGK F Q  H   HQ  H   +P
Sbjct: 512 PYKCNECGKVFTQNSHLANHQRIHTGVKP 540


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.321    0.133    0.413 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 28,776,568
Number of Sequences: 37866
Number of extensions: 1409539
Number of successful extensions: 65008
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 1056
Number of HSP's successfully gapped in prelim test: 30
Number of HSP's that attempted gapping in prelim test: 3433
Number of HSP's gapped (non-prelim): 21455
length of query: 691
length of database: 18,247,518
effective HSP length: 109
effective length of query: 582
effective length of database: 14,120,124
effective search space: 8217912168
effective search space used: 8217912168
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 65 (29.6 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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