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Search of human proteins with 46094065
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|46094065 mitochondrial carrier family protein [Homo sapiens]
(338 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|46094065 mitochondrial carrier family protein [Homo sapiens] 690 0.0
gi|7706306 solute carrier family 25, member 39 isoform b [Homo s... 348 4e-96
gi|219555665 solute carrier family 25, member 39 isoform a [Homo... 347 1e-95
gi|148491091 solute carrier family 25 member 24 isoform 1 [Homo ... 100 2e-21
gi|47458041 solute carrier family 25 member 24 isoform 2 [Homo s... 100 2e-21
gi|149274643 solute carrier family 25, member 28 [Homo sapiens] 100 3e-21
gi|21687151 mitochondrial solute carrier protein [Homo sapiens] 96 3e-20
gi|157388925 solute carrier family 25, member 38 [Homo sapiens] 96 6e-20
gi|48476342 solute carrier family 25, member 23 [Homo sapiens] 95 8e-20
gi|186928856 solute carrier family 25, member 19 [Homo sapiens] 93 3e-19
gi|186928860 solute carrier family 25, member 19 [Homo sapiens] 93 3e-19
gi|186928858 solute carrier family 25, member 19 [Homo sapiens] 93 3e-19
gi|60460887 solute carrier family 25, member 42 [Homo sapiens] 92 7e-19
gi|239755176 PREDICTED: similar to solute carrier family 25, mem... 92 9e-19
gi|239755174 PREDICTED: similar to solute carrier family 25, mem... 92 9e-19
gi|56699407 solute carrier family 25, member 25 isoform c [Homo ... 92 9e-19
gi|56699401 solute carrier family 25, member 25 isoform a [Homo ... 92 9e-19
gi|56699405 solute carrier family 25, member 25 isoform d [Homo ... 92 9e-19
gi|56699403 solute carrier family 25, member 25 isoform b [Homo ... 92 9e-19
gi|13449279 solute carrier family 25 (mitochondrial oxodicarboxy... 89 4e-18
gi|82775373 solute carrier family 25, member 37 [Homo sapiens] 89 6e-18
gi|149274607 solute carrier family 25, member 41 [Homo sapiens] 88 1e-17
gi|4507009 solute carrier family 25, member 14 isoform UCP5L [Ho... 87 2e-17
gi|13259543 solute carrier family 25, member 14 isoform UCP5S [H... 87 2e-17
gi|7657581 solute carrier family 25, member 13 isoform 2 [Homo s... 87 3e-17
gi|237649019 solute carrier family 25, member 13 isoform 1 [Homo... 87 3e-17
gi|27544933 solute carrier family 25, member 16 [Homo sapiens] 85 8e-17
gi|157388989 solute carrier family 25, member 36 isoform a [Homo... 84 2e-16
gi|4557403 carnitine/acylcarnitine translocase [Homo sapiens] 84 2e-16
gi|21361103 solute carrier family 25, member 12 [Homo sapiens] 82 5e-16
>gi|46094065 mitochondrial carrier family protein [Homo sapiens]
Length = 338
Score = 690 bits (1781), Expect = 0.0
Identities = 338/338 (100%), Positives = 338/338 (100%)
Query: 1 MDPETRGQEIIKVTPLQQMLASCTGAILTSVIVTPLDVVKIRLQAQNNPLPKGKCFVYSN 60
MDPETRGQEIIKVTPLQQMLASCTGAILTSVIVTPLDVVKIRLQAQNNPLPKGKCFVYSN
Sbjct: 1 MDPETRGQEIIKVTPLQQMLASCTGAILTSVIVTPLDVVKIRLQAQNNPLPKGKCFVYSN 60
Query: 61 GLMDHLCVCEEGGNKLWYKKPGNFQGTLDAFFKIIRNEGIKSLWSGLPPTLVMAVPATVI 120
GLMDHLCVCEEGGNKLWYKKPGNFQGTLDAFFKIIRNEGIKSLWSGLPPTLVMAVPATVI
Sbjct: 61 GLMDHLCVCEEGGNKLWYKKPGNFQGTLDAFFKIIRNEGIKSLWSGLPPTLVMAVPATVI 120
Query: 121 YFTCYDQLSALLRSKLGENETCIPIVAGIVARFGAVTVISPLELIRTKMQSKKFSYVELH 180
YFTCYDQLSALLRSKLGENETCIPIVAGIVARFGAVTVISPLELIRTKMQSKKFSYVELH
Sbjct: 121 YFTCYDQLSALLRSKLGENETCIPIVAGIVARFGAVTVISPLELIRTKMQSKKFSYVELH 180
Query: 181 RFVSKKVSEDGWISLWRGWAPTVLRDVPFSAMYWYNYEILKKWLCEKSGLYEPTFMINFT 240
RFVSKKVSEDGWISLWRGWAPTVLRDVPFSAMYWYNYEILKKWLCEKSGLYEPTFMINFT
Sbjct: 181 RFVSKKVSEDGWISLWRGWAPTVLRDVPFSAMYWYNYEILKKWLCEKSGLYEPTFMINFT 240
Query: 241 SGALSGSFAAVATLPFDVVKTQKQTQLWTYESHKISMPLHMSTWIIMKNIVAKNGFSGLF 300
SGALSGSFAAVATLPFDVVKTQKQTQLWTYESHKISMPLHMSTWIIMKNIVAKNGFSGLF
Sbjct: 241 SGALSGSFAAVATLPFDVVKTQKQTQLWTYESHKISMPLHMSTWIIMKNIVAKNGFSGLF 300
Query: 301 SGLIPRLIKIAPACAIMISTYEFGKAFFQKQNVRRQQY 338
SGLIPRLIKIAPACAIMISTYEFGKAFFQKQNVRRQQY
Sbjct: 301 SGLIPRLIKIAPACAIMISTYEFGKAFFQKQNVRRQQY 338
>gi|7706306 solute carrier family 25, member 39 isoform b [Homo
sapiens]
Length = 351
Score = 348 bits (893), Expect = 4e-96
Identities = 177/345 (51%), Positives = 240/345 (69%), Gaps = 18/345 (5%)
Query: 8 QEIIKVTPLQQMLASCTGAILTSVIVTPLDVVKIRLQAQNNPLP---------------K 52
Q+ ++PLQQM+AS TGA++TS+ +TPLDVVK+RLQ+Q + K
Sbjct: 4 QDPAGISPLQQMVASGTGAVVTSLFMTPLDVVKVRLQSQRPSMASELMPSSRLWSLSYTK 63
Query: 53 GKCFVYSNGLMDHLCVCEEGGN-KLWYKKPGNFQGTLDAFFKIIRNEGIKSLWSGLPPTL 111
KC +Y NG+++ L +C G W++ P F GT+DAF KI+R+EG ++LWSGLP TL
Sbjct: 64 WKCLLYCNGVLEPLYLCPNGARCATWFQDPTRFTGTMDAFVKIVRHEGTRTLWSGLPATL 123
Query: 112 VMAVPATVIYFTCYDQLSALLRSKLGENETCIPIVAGIVARFGAVTVISPLELIRTKMQS 171
VM VPAT IYFT YDQL A L + ++ P+VAG +AR G VTVISPLEL+RTK+Q+
Sbjct: 124 VMTVPATAIYFTAYDQLKAFLCGRALTSDLYAPMVAGALARLGTVTVISPLELMRTKLQA 183
Query: 172 KKFSYVELHRFVSKKVSEDGWISLWRGWAPTVLRDVPFSAMYWYNYEILKKWLCEKSGLY 231
+ SY EL V V++ GW SLW GW PT LRDVPFSA+YW+NYE++K WL
Sbjct: 184 QHVSYRELGACVRTAVAQGGWRSLWLGWGPTALRDVPFSALYWFNYELVKSWLNGFRPKD 243
Query: 232 EPTFMINFTSGALSGSFAAVATLPFDVVKTQKQTQLWTYESHKISMPLHM-STWIIMKNI 290
+ + ++F +G +SG+ AAV TLPFDVVKTQ+Q L E+ +++ PLH+ STW++++ I
Sbjct: 244 QTSVGMSFVAGGISGTVAAVLTLPFDVVKTQRQVALGAMEAVRVN-PLHVDSTWLLLRRI 302
Query: 291 VAKNGFSGLFSGLIPRLIKIAPACAIMISTYEFGKAFFQKQNVRR 335
A++G GLF+G +PR+IK AP+CAIMISTYEFGK+FFQ+ N R
Sbjct: 303 RAESGTKGLFAGFLPRIIKAAPSCAIMISTYEFGKSFFQRLNQDR 347
>gi|219555665 solute carrier family 25, member 39 isoform a [Homo
sapiens]
Length = 359
Score = 347 bits (889), Expect = 1e-95
Identities = 179/353 (50%), Positives = 241/353 (68%), Gaps = 26/353 (7%)
Query: 8 QEIIKVTPLQQMLASCTGAILTSVIVTPLDVVKIRLQAQN------------------NP 49
Q+ ++PLQQM+AS TGA++TS+ +TPLDVVK+RLQ+Q
Sbjct: 4 QDPAGISPLQQMVASGTGAVVTSLFMTPLDVVKVRLQSQRPSMASELMPSSRLWSLSYTK 63
Query: 50 LPK-----GKCFVYSNGLMDHLCVCEEGGN-KLWYKKPGNFQGTLDAFFKIIRNEGIKSL 103
LP GKC +Y NG+++ L +C G W++ P F GT+DAF KI+R+EG ++L
Sbjct: 64 LPSSLQSTGKCLLYCNGVLEPLYLCPNGARCATWFQDPTRFTGTMDAFVKIVRHEGTRTL 123
Query: 104 WSGLPPTLVMAVPATVIYFTCYDQLSALLRSKLGENETCIPIVAGIVARFGAVTVISPLE 163
WSGLP TLVM VPAT IYFT YDQL A L + ++ P+VAG +AR G VTVISPLE
Sbjct: 124 WSGLPATLVMTVPATAIYFTAYDQLKAFLCGRALTSDLYAPMVAGALARLGTVTVISPLE 183
Query: 164 LIRTKMQSKKFSYVELHRFVSKKVSEDGWISLWRGWAPTVLRDVPFSAMYWYNYEILKKW 223
L+RTK+Q++ SY EL V V++ GW SLW GW PT LRDVPFSA+YW+NYE++K W
Sbjct: 184 LMRTKLQAQHVSYRELGACVRTAVAQGGWRSLWLGWGPTALRDVPFSALYWFNYELVKSW 243
Query: 224 LCEKSGLYEPTFMINFTSGALSGSFAAVATLPFDVVKTQKQTQLWTYESHKISMPLHM-S 282
L + + ++F +G +SG+ AAV TLPFDVVKTQ+Q L E+ +++ PLH+ S
Sbjct: 244 LNGFRPKDQTSVGMSFVAGGISGTVAAVLTLPFDVVKTQRQVALGAMEAVRVN-PLHVDS 302
Query: 283 TWIIMKNIVAKNGFSGLFSGLIPRLIKIAPACAIMISTYEFGKAFFQKQNVRR 335
TW++++ I A++G GLF+G +PR+IK AP+CAIMISTYEFGK+FFQ+ N R
Sbjct: 303 TWLLLRRIRAESGTKGLFAGFLPRIIKAAPSCAIMISTYEFGKSFFQRLNQDR 355
>gi|148491091 solute carrier family 25 member 24 isoform 1 [Homo
sapiens]
Length = 477
Score = 100 bits (249), Expect = 2e-21
Identities = 75/309 (24%), Positives = 136/309 (44%), Gaps = 41/309 (13%)
Query: 17 QQMLASCTGAILTSVIVTPLDVVKIRLQAQNNPLPKGKCFVYSNGLMDHLCVCEEGGNKL 76
+Q+LA ++ PLD +KI +Q + K F GG
Sbjct: 196 RQLLAGGIAGAVSRTSTAPLDRLKIMMQVHGSKSDKMNIF---------------GG--- 237
Query: 77 WYKKPGNFQGTLDAFFKIIRNEGIKSLWSGLPPTLVMAVPATVIYFTCYDQLSALLRSKL 136
F ++++ GI+SLW G ++ P T + F Y+Q LL +
Sbjct: 238 --------------FRQMVKEGGIRSLWRGNGTNVIKIAPETAVKFWAYEQYKKLLTEEG 283
Query: 137 GENETCIPIVAGIVARFGAVTVISPLELIRTKMQ-SKKFSYVELHRFVSKKVSEDGWISL 195
+ T ++G +A A T I P+E+++T++ K Y ++ K + +G +
Sbjct: 284 QKIGTFERFISGSMAGATAQTFIYPMEVMKTRLAVGKTGQYSGIYDCAKKILKHEGLGAF 343
Query: 196 WRGWAPTVLRDVPFSAMYWYNYEILKKWLCEK--SGLYEPTFMINFTSGALSGSFAAVAT 253
++G+ P +L +P++ + YE+LK + + P M+ GALS + +A+
Sbjct: 344 YKGYVPNLLGIIPYAGIDLAVYELLKSYWLDNFAKDSVNPGVMVLLGCGALSSTCGQLAS 403
Query: 254 LPFDVVKTQKQTQLWTYESHKISMPLHMSTWIIMKNIVAKNGFSGLFSGLIPRLIKIAPA 313
P +V+T+ Q Q S +++M + + I++K G GL+ G+ P +K+ PA
Sbjct: 404 YPLALVRTRMQAQAMLEGSPQLNMV------GLFRRIISKEGIPGLYRGITPNFMKVLPA 457
Query: 314 CAIMISTYE 322
I YE
Sbjct: 458 VGISYVVYE 466
Score = 63.9 bits (154), Expect = 2e-10
Identities = 51/188 (27%), Positives = 85/188 (45%), Gaps = 23/188 (12%)
Query: 146 VAGIVARFGAVTVISPLELIRTKMQ--SKKFSYVELHRFVSKKVSEDGWISLWRGWAPTV 203
+AG V+R T +PL+ ++ MQ K + + + V E G SLWRG V
Sbjct: 203 IAGAVSR----TSTAPLDRLKIMMQVHGSKSDKMNIFGGFRQMVKEGGIRSLWRGNGTNV 258
Query: 204 LRDVPFSAMYWYNYEILKKWLCE---KSGLYEPTFMINFTSGALSGSFAAVATLPFDVVK 260
++ P +A+ ++ YE KK L E K G +E F SG+++G+ A P +V+K
Sbjct: 259 IKIAPETAVKFWAYEQYKKLLTEEGQKIGTFE-----RFISGSMAGATAQTFIYPMEVMK 313
Query: 261 TQKQTQLWTYESHKISMPLHMSTWIIMKNIVAKNGFSGLFSGLIPRLIKIAPACAIMIST 320
T+ + + K I+ G + G +P L+ I P I ++
Sbjct: 314 TRLAVG---------KTGQYSGIYDCAKKILKHEGLGAFYKGYVPNLLGIIPYAGIDLAV 364
Query: 321 YEFGKAFF 328
YE K+++
Sbjct: 365 YELLKSYW 372
Score = 53.1 bits (126), Expect = 3e-07
Identities = 43/160 (26%), Positives = 75/160 (46%), Gaps = 22/160 (13%)
Query: 80 KPGNFQGTLDAFFKIIRNEGIKSLWSGLPPTLVMAVPATVIYFTCYDQLSALLRSKLGEN 139
K G + G D KI+++EG+ + + G P L+ +P I Y+ LL+S +N
Sbjct: 320 KTGQYSGIYDCAKKILKHEGLGAFYKGYVPNLLGIIPYAGIDLAVYE----LLKSYWLDN 375
Query: 140 ETCIPIVAGIVARFGAVTVIS--------PLELIRTKMQ-------SKKFSYVELHRFVS 184
+ G++ G + S PL L+RT+MQ S + + V L R +
Sbjct: 376 FAKDSVNPGVMVLLGCGALSSTCGQLASYPLALVRTRMQAQAMLEGSPQLNMVGLFRRI- 434
Query: 185 KKVSEDGWISLWRGWAPTVLRDVPFSAMYWYNYEILKKWL 224
+S++G L+RG P ++ +P + + YE +K+ L
Sbjct: 435 --ISKEGIPGLYRGITPNFMKVLPAVGISYVVYENMKQTL 472
>gi|47458041 solute carrier family 25 member 24 isoform 2 [Homo
sapiens]
Length = 458
Score = 100 bits (249), Expect = 2e-21
Identities = 75/309 (24%), Positives = 136/309 (44%), Gaps = 41/309 (13%)
Query: 17 QQMLASCTGAILTSVIVTPLDVVKIRLQAQNNPLPKGKCFVYSNGLMDHLCVCEEGGNKL 76
+Q+LA ++ PLD +KI +Q + K F GG
Sbjct: 177 RQLLAGGIAGAVSRTSTAPLDRLKIMMQVHGSKSDKMNIF---------------GG--- 218
Query: 77 WYKKPGNFQGTLDAFFKIIRNEGIKSLWSGLPPTLVMAVPATVIYFTCYDQLSALLRSKL 136
F ++++ GI+SLW G ++ P T + F Y+Q LL +
Sbjct: 219 --------------FRQMVKEGGIRSLWRGNGTNVIKIAPETAVKFWAYEQYKKLLTEEG 264
Query: 137 GENETCIPIVAGIVARFGAVTVISPLELIRTKMQ-SKKFSYVELHRFVSKKVSEDGWISL 195
+ T ++G +A A T I P+E+++T++ K Y ++ K + +G +
Sbjct: 265 QKIGTFERFISGSMAGATAQTFIYPMEVMKTRLAVGKTGQYSGIYDCAKKILKHEGLGAF 324
Query: 196 WRGWAPTVLRDVPFSAMYWYNYEILKKWLCEK--SGLYEPTFMINFTSGALSGSFAAVAT 253
++G+ P +L +P++ + YE+LK + + P M+ GALS + +A+
Sbjct: 325 YKGYVPNLLGIIPYAGIDLAVYELLKSYWLDNFAKDSVNPGVMVLLGCGALSSTCGQLAS 384
Query: 254 LPFDVVKTQKQTQLWTYESHKISMPLHMSTWIIMKNIVAKNGFSGLFSGLIPRLIKIAPA 313
P +V+T+ Q Q S +++M + + I++K G GL+ G+ P +K+ PA
Sbjct: 385 YPLALVRTRMQAQAMLEGSPQLNMV------GLFRRIISKEGIPGLYRGITPNFMKVLPA 438
Query: 314 CAIMISTYE 322
I YE
Sbjct: 439 VGISYVVYE 447
Score = 63.9 bits (154), Expect = 2e-10
Identities = 51/188 (27%), Positives = 85/188 (45%), Gaps = 23/188 (12%)
Query: 146 VAGIVARFGAVTVISPLELIRTKMQ--SKKFSYVELHRFVSKKVSEDGWISLWRGWAPTV 203
+AG V+R T +PL+ ++ MQ K + + + V E G SLWRG V
Sbjct: 184 IAGAVSR----TSTAPLDRLKIMMQVHGSKSDKMNIFGGFRQMVKEGGIRSLWRGNGTNV 239
Query: 204 LRDVPFSAMYWYNYEILKKWLCE---KSGLYEPTFMINFTSGALSGSFAAVATLPFDVVK 260
++ P +A+ ++ YE KK L E K G +E F SG+++G+ A P +V+K
Sbjct: 240 IKIAPETAVKFWAYEQYKKLLTEEGQKIGTFE-----RFISGSMAGATAQTFIYPMEVMK 294
Query: 261 TQKQTQLWTYESHKISMPLHMSTWIIMKNIVAKNGFSGLFSGLIPRLIKIAPACAIMIST 320
T+ + + K I+ G + G +P L+ I P I ++
Sbjct: 295 TRLAVG---------KTGQYSGIYDCAKKILKHEGLGAFYKGYVPNLLGIIPYAGIDLAV 345
Query: 321 YEFGKAFF 328
YE K+++
Sbjct: 346 YELLKSYW 353
Score = 53.1 bits (126), Expect = 3e-07
Identities = 43/160 (26%), Positives = 75/160 (46%), Gaps = 22/160 (13%)
Query: 80 KPGNFQGTLDAFFKIIRNEGIKSLWSGLPPTLVMAVPATVIYFTCYDQLSALLRSKLGEN 139
K G + G D KI+++EG+ + + G P L+ +P I Y+ LL+S +N
Sbjct: 301 KTGQYSGIYDCAKKILKHEGLGAFYKGYVPNLLGIIPYAGIDLAVYE----LLKSYWLDN 356
Query: 140 ETCIPIVAGIVARFGAVTVIS--------PLELIRTKMQ-------SKKFSYVELHRFVS 184
+ G++ G + S PL L+RT+MQ S + + V L R +
Sbjct: 357 FAKDSVNPGVMVLLGCGALSSTCGQLASYPLALVRTRMQAQAMLEGSPQLNMVGLFRRI- 415
Query: 185 KKVSEDGWISLWRGWAPTVLRDVPFSAMYWYNYEILKKWL 224
+S++G L+RG P ++ +P + + YE +K+ L
Sbjct: 416 --ISKEGIPGLYRGITPNFMKVLPAVGISYVVYENMKQTL 453
>gi|149274643 solute carrier family 25, member 28 [Homo sapiens]
Length = 364
Score = 99.8 bits (247), Expect = 3e-21
Identities = 86/325 (26%), Positives = 137/325 (42%), Gaps = 46/325 (14%)
Query: 14 TPLQQMLASCTGAILTSVIVTPLDVVKIRLQAQNNPLPKGKCFVYSNGLMDHLCVCEEGG 73
T M+A IL ++ P+D VK R+Q+ P P +
Sbjct: 71 TVTTHMVAGAVAGILEHCVMYPIDCVKTRMQSLQ-PDPAAR------------------- 110
Query: 74 NKLWYKKPGNFQGTLDAFFKIIRNEGIKSLWSGLPPTLVMAVPATVIYFTCYDQLSALLR 133
++ L+A ++IIR EG+ GL T A PA +YF CY++L L
Sbjct: 111 ----------YRNVLEALWRIIRTEGLWRPMRGLNVTATGAGPAHALYFACYEKLKKTLS 160
Query: 134 SKL--GENETCIPIVAGIVARFGAVTVISPLELIRTKMQSKKFSYVELHRFVSKKVSEDG 191
+ G N AG VA ++P E+++ +MQ Y + V +G
Sbjct: 161 DVIHPGGNSHIANGAAGCVATLLHDAAMNPAEVVKQRMQMYNSPYHRVTDCVRAVWQNEG 220
Query: 192 WISLWRGWAPTVLRDVPFSAMYWYNYEILKKWLCEKSGLYEPTFMINFTSGALSGSFAAV 251
+ +R + + +VPF A+++ YE L++ Y P+ + SGA +G+ AA
Sbjct: 221 AGAFYRSYTTQLTMNVPFQAIHFMTYEFLQEHF-NPQRRYNPSSHV--LSGACAGAVAAA 277
Query: 252 ATLPFDVVKTQKQTQLWTYESHKISMPLHMSTWI-----IMKNIVAKNGFSGLFSGLIPR 306
AT P DV KT TQ +++ H++ I + + G + F G+ R
Sbjct: 278 ATTPLDVCKTLLNTQ------ESLALNSHITGHITGMASAFRTVYQVGGVTAYFRGVQAR 331
Query: 307 LIKIAPACAIMISTYEFGKAFFQKQ 331
+I P+ AI S YEF K K+
Sbjct: 332 VIYQIPSTAIAWSVYEFFKYLITKR 356
Score = 32.0 bits (71), Expect = 0.81
Identities = 26/117 (22%), Positives = 46/117 (39%), Gaps = 26/117 (22%)
Query: 22 SCTGAILTSVIVTPLDVVKIRLQAQNNPLPKGKCFVYSNGLMDHLCVCEEGGNKLWYKKP 81
+C GA+ + TPLDV K L Q S L H+
Sbjct: 269 ACAGAVAAAA-TTPLDVCKTLLNTQE-----------SLALNSHI--------------T 302
Query: 82 GNFQGTLDAFFKIIRNEGIKSLWSGLPPTLVMAVPATVIYFTCYDQLSALLRSKLGE 138
G+ G AF + + G+ + + G+ ++ +P+T I ++ Y+ L+ + E
Sbjct: 303 GHITGMASAFRTVYQVGGVTAYFRGVQARVIYQIPSTAIAWSVYEFFKYLITKRQEE 359
>gi|21687151 mitochondrial solute carrier protein [Homo sapiens]
Length = 341
Score = 96.3 bits (238), Expect = 3e-20
Identities = 74/256 (28%), Positives = 118/256 (46%), Gaps = 9/256 (3%)
Query: 82 GNFQGTLDAFFKIIRNEGIKSLWSGLPPTLVMAVPATVIYFTCYDQLSALLRSKLGENET 141
G+ +G ++ R EG+++LW G + P + + Y + L LG
Sbjct: 47 GHARGPWATGHRVWRAEGLRALWKGNAVACLRLFPCSAVQLAAYRKFVVLFTDDLGHISQ 106
Query: 142 CIPIVAGIVARFGAVTVISPLELIRTKMQSKKF---SYVELHRFVSKKVSEDGWISLWRG 198
I+AG +A + V P +LI+T++ + SY L S ++G+++L+RG
Sbjct: 107 WSSIMAGSLAGMVSTIVTYPTDLIKTRLIMQNILEPSYRGLLHAFSTIYQQEGFLALYRG 166
Query: 199 WAPTVLRDVPFSAMYWYNYEILKK-WLCEKSGLYEPTFMINFTSGALSGSFAAVATLPFD 257
+ TV+ +PFSA Y L+K W + P NF + L+ + + PF+
Sbjct: 167 VSLTVVGALPFSAGSLLVYMNLEKIWNGPRDQFSLPQ---NFANVCLAAAVTQTLSFPFE 223
Query: 258 VVKTQKQTQLWTYESHKISMPLHMSTWI-IMKNIVAKNGFSGLFSGLIPRLIKIAPACAI 316
VK + Q Q Y H + +H S + + IV G GL++GL L+KI P I
Sbjct: 224 TVKRKMQAQS-PYLPHSGGVDVHFSGAVDCFRQIVKAQGVLGLWNGLTANLLKIVPYFGI 282
Query: 317 MISTYEFGKAFFQKQN 332
M ST+EF K QN
Sbjct: 283 MFSTFEFCKRICLYQN 298
Score = 45.4 bits (106), Expect = 7e-05
Identities = 48/245 (19%), Positives = 93/245 (37%), Gaps = 51/245 (20%)
Query: 13 VTPLQQMLASCTGAILTSVIVTPLDVVKIRLQAQNNPLPKGKCFVYSNGLMDHLCVCEEG 72
++ ++A ++++++ P D++K RL QN P
Sbjct: 104 ISQWSSIMAGSLAGMVSTIVTYPTDLIKTRLIMQNILEP--------------------- 142
Query: 73 GNKLWYKKPGNFQGTLDAFFKIIRNEGIKSLWSGLPPTLVMAVPATVIYFTCYDQLSALL 132
+++G L AF I + EG +L+ G+ T+V A+P + Y L +
Sbjct: 143 ----------SYRGLLHAFSTIYQQEGFLALYRGVSLTVVGALPFSAGSLLVYMNLEKIW 192
Query: 133 RS-----KLGENETCIPIVAGIVARFGAVTVISPLELIRTKMQSKK-----FSYVELH-- 180
L +N + + A + T+ P E ++ KMQ++ V++H
Sbjct: 193 NGPRDQFSLPQNFANVCLAAAVTQ-----TLSFPFETVKRKMQAQSPYLPHSGGVDVHFS 247
Query: 181 ---RFVSKKVSEDGWISLWRGWAPTVLRDVPFSAMYWYNYEILKKWLCEKSGLYEPTFMI 237
+ V G + LW G +L+ VP+ + + +E K+ ++G
Sbjct: 248 GAVDCFRQIVKAQGVLGLWNGLTANLLKIVPYFGIMFSTFEFCKRICLYQNGYILSPLSY 307
Query: 238 NFTSG 242
T G
Sbjct: 308 KLTPG 312
>gi|157388925 solute carrier family 25, member 38 [Homo sapiens]
Length = 304
Score = 95.5 bits (236), Expect = 6e-20
Identities = 68/239 (28%), Positives = 110/239 (46%), Gaps = 15/239 (6%)
Query: 86 GTLDAFFKIIRNEGIKSLWSGLPPTLVMAVPATVIYF-TCYDQLSALLRSKLGENETCIP 144
G L K++R E + LW G+ P++V VP IYF T Y LR G T +
Sbjct: 69 GMLAVLLKVVRTESLLGLWKGMSPSIVRCVPGVGIYFGTLYSLKQYFLR---GHPPTALE 125
Query: 145 -IVAGIVARFGAVTVISPLELIRTKMQSKKFSYVELHRFVSKKVSEDGWISLWRGWAPTV 203
++ G+ +R A +SP+ +I+T+ +S K+ Y ++ + +G L+ G T+
Sbjct: 126 SVMLGVGSRSVAGVCMSPITVIKTRYESGKYGYESIYAALRSIYHSEGHRGLFSGLTATL 185
Query: 204 LRDVPFSAMYWYNYEILKKWLCEKSGLYEPTFMINFTSGALSGSFAAVATLPFDVVKTQK 263
LRD PFS +Y Y K + + NF+ G +G A++ T P DV+KT
Sbjct: 186 LRDAPFSGIYLMFYNQTKNIVPHDQVDATLIPITNFSCGIFAGILASLVTQPADVIKTHM 245
Query: 264 QTQLWTYESHKISMPLHMSTWIIMKNIVAKNGFSGLFSGLIPRLIKIAPACAIMISTYE 322
Q ++ + + +I K+ G G F G IPR ++ A+ + YE
Sbjct: 246 QLYPLKFQW------IGQAVTLIFKDY----GLRGFFQGGIPRALRRTLMAAMAWTVYE 294
Score = 51.2 bits (121), Expect = 1e-06
Identities = 40/138 (28%), Positives = 62/138 (44%), Gaps = 4/138 (2%)
Query: 84 FQGTLDAFFKIIRNEGIKSLWSGLPPTLVMAVPATVIYFTCYDQLSALLRSKLGENETCI 143
++ A I +EG + L+SGL TL+ P + IY Y+Q ++ + T I
Sbjct: 158 YESIYAALRSIYHSEGHRGLFSGLTATLLRDAPFSGIYLMFYNQTKNIVPHD-QVDATLI 216
Query: 144 PIV---AGIVARFGAVTVISPLELIRTKMQSKKFSYVELHRFVSKKVSEDGWISLWRGWA 200
PI GI A A V P ++I+T MQ + + + V+ + G ++G
Sbjct: 217 PITNFSCGIFAGILASLVTQPADVIKTHMQLYPLKFQWIGQAVTLIFKDYGLRGFFQGGI 276
Query: 201 PTVLRDVPFSAMYWYNYE 218
P LR +AM W YE
Sbjct: 277 PRALRRTLMAAMAWTVYE 294
Score = 37.7 bits (86), Expect = 0.015
Identities = 23/91 (25%), Positives = 43/91 (47%), Gaps = 7/91 (7%)
Query: 239 FTSGALSGSFAAVATLPFDVVKTQKQT-QLWTYESHKISMPLHMSTWIIMKNIVAKNGFS 297
F G++SG+ + + P D++KT+ QT Q + S ++ M ++ +V
Sbjct: 31 FLCGSISGTCSTLLFQPLDLLKTRLQTLQPSDHGSRRVGM------LAVLLKVVRTESLL 84
Query: 298 GLFSGLIPRLIKIAPACAIMISTYEFGKAFF 328
GL+ G+ P +++ P I T K +F
Sbjct: 85 GLWKGMSPSIVRCVPGVGIYFGTLYSLKQYF 115
>gi|48476342 solute carrier family 25, member 23 [Homo sapiens]
Length = 468
Score = 95.1 bits (235), Expect = 8e-20
Identities = 63/230 (27%), Positives = 117/230 (50%), Gaps = 15/230 (6%)
Query: 99 GIKSLWSGLPPTLVMAVPATVIYFTCYDQLSALLRSKLGENETCIP---IVAGIVARFGA 155
GI+SLW G ++ P + I F Y+Q+ R+ LG+ ET VAG +A A
Sbjct: 237 GIRSLWRGNGINVLKIAPESAIKFMAYEQIK---RAILGQQETLHVQERFVAGSLAGATA 293
Query: 156 VTVISPLELIRTKMQSKKFS-YVELHRFVSKKVSEDGWISLWRGWAPTVLRDVPFSAMYW 214
T+I P+E+++T++ ++ Y L + + +G + +RG+ P VL +P++ +
Sbjct: 294 QTIIYPMEVLKTRLTLRRTGQYKGLLDCARRILEREGPRAFYRGYLPNVLGIIPYAGIDL 353
Query: 215 YNYEILKKWLCEKSG--LYEPTFMINFTSGALSGSFAAVATLPFDVVKTQKQTQLWTYES 272
YE LK W ++ +P ++ G +S + +A+ P +V+T+ Q Q
Sbjct: 354 AVYETLKNWWLQQYSHDSADPGILVLLACGTISSTCGQIASYPLALVRTRMQAQASIEGG 413
Query: 273 HKISMPLHMSTWIIMKNIVAKNGFSGLFSGLIPRLIKIAPACAIMISTYE 322
++SM ++++I+++ G GL+ G+ P +K+ PA +I YE
Sbjct: 414 PQLSM------LGLLRHILSQEGMRGLYRGIAPNFMKVIPAVSISYVVYE 457
Score = 52.0 bits (123), Expect = 8e-07
Identities = 37/161 (22%), Positives = 76/161 (47%), Gaps = 14/161 (8%)
Query: 75 KLWYKKPGNFQGTLDAFFKIIRNEGIKSLWSGLPPTLVMAVPATVIYFTCYDQLSALLRS 134
+L ++ G ++G LD +I+ EG ++ + G P ++ +P I Y+ L
Sbjct: 306 RLTLRRTGQYKGLLDCARRILEREGPRAFYRGYLPNVLGIIPYAGIDLAVYETLKNWWLQ 365
Query: 135 KLGENET----CIPIVAGIVARFGAVTVISPLELIRTKMQSK-------KFSYVELHRFV 183
+ + + + G ++ PL L+RT+MQ++ + S + L R +
Sbjct: 366 QYSHDSADPGILVLLACGTISSTCGQIASYPLALVRTRMQAQASIEGGPQLSMLGLLRHI 425
Query: 184 SKKVSEDGWISLWRGWAPTVLRDVPFSAMYWYNYEILKKWL 224
+S++G L+RG AP ++ +P ++ + YE +K+ L
Sbjct: 426 ---LSQEGMRGLYRGIAPNFMKVIPAVSISYVVYENMKQAL 463
Score = 29.6 bits (65), Expect = 4.0
Identities = 21/82 (25%), Positives = 37/82 (45%), Gaps = 8/82 (9%)
Query: 241 SGALSGSFAAVATLPFDVVKTQKQTQLWTYESHKISMPLHMSTWIIMKNIVAKNGFSGLF 300
+GA++G+ + T P D +K Q S ++ ++++V + G L+
Sbjct: 191 AGAVAGAVSRTGTAPLDRLKVFMQVHA--------SKTNRLNILGGLRSMVLEGGIRSLW 242
Query: 301 SGLIPRLIKIAPACAIMISTYE 322
G ++KIAP AI YE
Sbjct: 243 RGNGINVLKIAPESAIKFMAYE 264
>gi|186928856 solute carrier family 25, member 19 [Homo sapiens]
Length = 320
Score = 93.2 bits (230), Expect = 3e-19
Identities = 78/332 (23%), Positives = 137/332 (41%), Gaps = 41/332 (12%)
Query: 2 DPETRGQEIIKVTPLQQMLASCTGAILTSVIVTPLDVVKIRLQAQNNPLPKGKCFVYSNG 61
DP+ G+ K Q +A ++T +++P DV+KIR Q Q+ L +
Sbjct: 5 DPKPDGRNNTK---FQVAVAGSVSGLVTRALISPFDVIKIRFQLQHERLSRS-------- 53
Query: 62 LMDHLCVCEEGGNKLWYKKPGNFQGTLDAFFKIIRNEGIKSLWSGLPPTLVMAVPATVIY 121
+ G L A +I++ EG + W G P ++++ +
Sbjct: 54 -----------------DPSAKYHGILQASRQILQEEGPTAFWKGHVPAQILSIGYGAVQ 96
Query: 122 FTCYDQLSALLR--SKLGENETCIPIVAGIVARFGAVTVISPLELIRTKM--QSKKFSYV 177
F ++ L+ L+ S E + V G +A A + P++++RT+ Q + Y
Sbjct: 97 FLSFEMLTELVHRGSVYDAREFSVHFVCGGLAACMATLTVHPVDVLRTRFAAQGEPKVYN 156
Query: 178 ELHRFVSKKVSEDGWISLWRGWAPTVLRDVPFSAMYWYNYEILK---KWLCEKSGLYEPT 234
L V +G ++G APT++ P++ + + Y LK KW G
Sbjct: 157 TLRHAVGTMYRSEGPQVFYKGLAPTLIAIFPYAGLQFSCYSSLKHLYKWAIPAEGKKNEN 216
Query: 235 FMINFTSGALSGSFAAVATLPFDVVKTQKQTQLWTYESHKIS---MPLHMSTWIIMKNIV 291
N G+ +G + T P D+ K K+ Q+ +E + + + + K ++
Sbjct: 217 LQ-NLLCGSGAGVISKTLTYPLDLFK--KRLQVGGFEHARAAFGQVRRYKGLMDCAKQVL 273
Query: 292 AKNGFSGLFSGLIPRLIKIAPACAIMISTYEF 323
K G G F GL P L+K A + M +YEF
Sbjct: 274 QKEGALGFFKGLSPSLLKAALSTGFMFFSYEF 305
Score = 54.7 bits (130), Expect = 1e-07
Identities = 47/204 (23%), Positives = 89/204 (43%), Gaps = 20/204 (9%)
Query: 137 GENETCIPI-VAGIVARFGAVTVISPLELIRTKMQ------SKKFSYVELHRFVSKK--- 186
G N T + VAG V+ +ISP ++I+ + Q S+ + H +
Sbjct: 10 GRNNTKFQVAVAGSVSGLVTRALISPFDVIKIRFQLQHERLSRSDPSAKYHGILQASRQI 69
Query: 187 VSEDGWISLWRGWAPTVLRDVPFSAMYWYNYEILKKWLCEKSGLYEP-TFMINFTSGALS 245
+ E+G + W+G P + + + A+ + ++E+L + L + +Y+ F ++F G L+
Sbjct: 70 LQEEGPTAFWKGHVPAQILSIGYGAVQFLSFEMLTE-LVHRGSVYDAREFSVHFVCGGLA 128
Query: 246 GSFAAVATLPFDVVKTQKQTQLWTYESHKISMPLHMSTWIIMKNIVAKNGFSGLFSGLIP 305
A + P DV++T+ Q K+ L + + ++ G + GL P
Sbjct: 129 ACMATLTVHPVDVLRTRFAAQ----GEPKVYNTLRHAVGTMYRS----EGPQVFYKGLAP 180
Query: 306 RLIKIAPACAIMISTYEFGKAFFQ 329
LI I P + S Y K ++
Sbjct: 181 TLIAIFPYAGLQFSCYSSLKHLYK 204
>gi|186928860 solute carrier family 25, member 19 [Homo sapiens]
Length = 320
Score = 93.2 bits (230), Expect = 3e-19
Identities = 78/332 (23%), Positives = 137/332 (41%), Gaps = 41/332 (12%)
Query: 2 DPETRGQEIIKVTPLQQMLASCTGAILTSVIVTPLDVVKIRLQAQNNPLPKGKCFVYSNG 61
DP+ G+ K Q +A ++T +++P DV+KIR Q Q+ L +
Sbjct: 5 DPKPDGRNNTK---FQVAVAGSVSGLVTRALISPFDVIKIRFQLQHERLSRS-------- 53
Query: 62 LMDHLCVCEEGGNKLWYKKPGNFQGTLDAFFKIIRNEGIKSLWSGLPPTLVMAVPATVIY 121
+ G L A +I++ EG + W G P ++++ +
Sbjct: 54 -----------------DPSAKYHGILQASRQILQEEGPTAFWKGHVPAQILSIGYGAVQ 96
Query: 122 FTCYDQLSALLR--SKLGENETCIPIVAGIVARFGAVTVISPLELIRTKM--QSKKFSYV 177
F ++ L+ L+ S E + V G +A A + P++++RT+ Q + Y
Sbjct: 97 FLSFEMLTELVHRGSVYDAREFSVHFVCGGLAACMATLTVHPVDVLRTRFAAQGEPKVYN 156
Query: 178 ELHRFVSKKVSEDGWISLWRGWAPTVLRDVPFSAMYWYNYEILK---KWLCEKSGLYEPT 234
L V +G ++G APT++ P++ + + Y LK KW G
Sbjct: 157 TLRHAVGTMYRSEGPQVFYKGLAPTLIAIFPYAGLQFSCYSSLKHLYKWAIPAEGKKNEN 216
Query: 235 FMINFTSGALSGSFAAVATLPFDVVKTQKQTQLWTYESHKIS---MPLHMSTWIIMKNIV 291
N G+ +G + T P D+ K K+ Q+ +E + + + + K ++
Sbjct: 217 LQ-NLLCGSGAGVISKTLTYPLDLFK--KRLQVGGFEHARAAFGQVRRYKGLMDCAKQVL 273
Query: 292 AKNGFSGLFSGLIPRLIKIAPACAIMISTYEF 323
K G G F GL P L+K A + M +YEF
Sbjct: 274 QKEGALGFFKGLSPSLLKAALSTGFMFFSYEF 305
Score = 54.7 bits (130), Expect = 1e-07
Identities = 47/204 (23%), Positives = 89/204 (43%), Gaps = 20/204 (9%)
Query: 137 GENETCIPI-VAGIVARFGAVTVISPLELIRTKMQ------SKKFSYVELHRFVSKK--- 186
G N T + VAG V+ +ISP ++I+ + Q S+ + H +
Sbjct: 10 GRNNTKFQVAVAGSVSGLVTRALISPFDVIKIRFQLQHERLSRSDPSAKYHGILQASRQI 69
Query: 187 VSEDGWISLWRGWAPTVLRDVPFSAMYWYNYEILKKWLCEKSGLYEP-TFMINFTSGALS 245
+ E+G + W+G P + + + A+ + ++E+L + L + +Y+ F ++F G L+
Sbjct: 70 LQEEGPTAFWKGHVPAQILSIGYGAVQFLSFEMLTE-LVHRGSVYDAREFSVHFVCGGLA 128
Query: 246 GSFAAVATLPFDVVKTQKQTQLWTYESHKISMPLHMSTWIIMKNIVAKNGFSGLFSGLIP 305
A + P DV++T+ Q K+ L + + ++ G + GL P
Sbjct: 129 ACMATLTVHPVDVLRTRFAAQ----GEPKVYNTLRHAVGTMYRS----EGPQVFYKGLAP 180
Query: 306 RLIKIAPACAIMISTYEFGKAFFQ 329
LI I P + S Y K ++
Sbjct: 181 TLIAIFPYAGLQFSCYSSLKHLYK 204
>gi|186928858 solute carrier family 25, member 19 [Homo sapiens]
Length = 320
Score = 93.2 bits (230), Expect = 3e-19
Identities = 78/332 (23%), Positives = 137/332 (41%), Gaps = 41/332 (12%)
Query: 2 DPETRGQEIIKVTPLQQMLASCTGAILTSVIVTPLDVVKIRLQAQNNPLPKGKCFVYSNG 61
DP+ G+ K Q +A ++T +++P DV+KIR Q Q+ L +
Sbjct: 5 DPKPDGRNNTK---FQVAVAGSVSGLVTRALISPFDVIKIRFQLQHERLSRS-------- 53
Query: 62 LMDHLCVCEEGGNKLWYKKPGNFQGTLDAFFKIIRNEGIKSLWSGLPPTLVMAVPATVIY 121
+ G L A +I++ EG + W G P ++++ +
Sbjct: 54 -----------------DPSAKYHGILQASRQILQEEGPTAFWKGHVPAQILSIGYGAVQ 96
Query: 122 FTCYDQLSALLR--SKLGENETCIPIVAGIVARFGAVTVISPLELIRTKM--QSKKFSYV 177
F ++ L+ L+ S E + V G +A A + P++++RT+ Q + Y
Sbjct: 97 FLSFEMLTELVHRGSVYDAREFSVHFVCGGLAACMATLTVHPVDVLRTRFAAQGEPKVYN 156
Query: 178 ELHRFVSKKVSEDGWISLWRGWAPTVLRDVPFSAMYWYNYEILK---KWLCEKSGLYEPT 234
L V +G ++G APT++ P++ + + Y LK KW G
Sbjct: 157 TLRHAVGTMYRSEGPQVFYKGLAPTLIAIFPYAGLQFSCYSSLKHLYKWAIPAEGKKNEN 216
Query: 235 FMINFTSGALSGSFAAVATLPFDVVKTQKQTQLWTYESHKIS---MPLHMSTWIIMKNIV 291
N G+ +G + T P D+ K K+ Q+ +E + + + + K ++
Sbjct: 217 LQ-NLLCGSGAGVISKTLTYPLDLFK--KRLQVGGFEHARAAFGQVRRYKGLMDCAKQVL 273
Query: 292 AKNGFSGLFSGLIPRLIKIAPACAIMISTYEF 323
K G G F GL P L+K A + M +YEF
Sbjct: 274 QKEGALGFFKGLSPSLLKAALSTGFMFFSYEF 305
Score = 54.7 bits (130), Expect = 1e-07
Identities = 47/204 (23%), Positives = 89/204 (43%), Gaps = 20/204 (9%)
Query: 137 GENETCIPI-VAGIVARFGAVTVISPLELIRTKMQ------SKKFSYVELHRFVSKK--- 186
G N T + VAG V+ +ISP ++I+ + Q S+ + H +
Sbjct: 10 GRNNTKFQVAVAGSVSGLVTRALISPFDVIKIRFQLQHERLSRSDPSAKYHGILQASRQI 69
Query: 187 VSEDGWISLWRGWAPTVLRDVPFSAMYWYNYEILKKWLCEKSGLYEP-TFMINFTSGALS 245
+ E+G + W+G P + + + A+ + ++E+L + L + +Y+ F ++F G L+
Sbjct: 70 LQEEGPTAFWKGHVPAQILSIGYGAVQFLSFEMLTE-LVHRGSVYDAREFSVHFVCGGLA 128
Query: 246 GSFAAVATLPFDVVKTQKQTQLWTYESHKISMPLHMSTWIIMKNIVAKNGFSGLFSGLIP 305
A + P DV++T+ Q K+ L + + ++ G + GL P
Sbjct: 129 ACMATLTVHPVDVLRTRFAAQ----GEPKVYNTLRHAVGTMYRS----EGPQVFYKGLAP 180
Query: 306 RLIKIAPACAIMISTYEFGKAFFQ 329
LI I P + S Y K ++
Sbjct: 181 TLIAIFPYAGLQFSCYSSLKHLYK 204
>gi|60460887 solute carrier family 25, member 42 [Homo sapiens]
Length = 318
Score = 92.0 bits (227), Expect = 7e-19
Identities = 70/233 (30%), Positives = 110/233 (47%), Gaps = 15/233 (6%)
Query: 97 NEGIKSLWSGLPPTLVMAVPATVIYFTCYDQLSALLRSKLGENETCIP----IVAGIVAR 152
NEG SLW G T+V VP I F+ +++ +L S G +P + AG +A
Sbjct: 83 NEGFLSLWRGNSATMVRVVPYAAIQFSAHEEYKRILGSYYGFRGEALPPWPRLFAGALAG 142
Query: 153 FGAVTVISPLELIRTKMQ-SKKFSYVELHRFVSKKVSEDGWISLWRGWAPTVLRDVPFSA 211
A ++ PL+L+R +M + K Y + + E+G +L+ G+ PTVL +P++
Sbjct: 143 TTAASLTYPLDLVRARMAVTPKEMYSNIFHVFIRISREEGLKTLYHGFMPTVLGVIPYAG 202
Query: 212 MYWYNYEILKKWLCEKSGLYEPTFMINFTSGALSGSFAAVATLPFDVVKTQKQTQLWT-Y 270
+ ++ YE LK E SG +P GA +G A+ P DVV+ + QT T Y
Sbjct: 203 LSFFTYETLKSLHREYSGRRQPYPFERMIFGACAGLIGQSASYPLDVVRRRMQTAGVTGY 262
Query: 271 ESHKISMPLHMSTWIIMKNIVAKNG-FSGLFSGLIPRLIKIAPACAIMISTYE 322
I+ L + IV + G GL+ GL +K A I +T++
Sbjct: 263 PRASIARTL--------RTIVREEGAVRGLYKGLSMNWVKGPIAVGISFTTFD 307
Score = 76.3 bits (186), Expect = 4e-14
Identities = 58/217 (26%), Positives = 104/217 (47%), Gaps = 17/217 (7%)
Query: 128 LSALLRSKLGENETCIPIVAGIVARFGAVTVISPLELIRTKM----QSKKFSYVELHRFV 183
LS+ + SK + ++ G +A A T ++PL+ RTK+ SK+FS E R +
Sbjct: 20 LSSSVSSKRDHRQVLSSLLPGALAGALAKTAVAPLD--RTKIIFQVSSKRFSAKEAFRVL 77
Query: 184 SKKVSEDGWISLWRGWAPTVLRDVPFSAMYWYNYEILKKWLCEKSGLYEPTF--MINFTS 241
+G++SLWRG + T++R VP++A+ + +E K+ L G +
Sbjct: 78 YYTYLNEGFLSLWRGNSATMVRVVPYAAIQFSAHEEYKRILGSYYGFRGEALPPWPRLFA 137
Query: 242 GALSGSFAAVATLPFDVVKTQKQTQLWTYESHKISMPLHMSTWIIMKNIVAKNGFSGLFS 301
GAL+G+ AA T P D+V+ + ++ + + + I + G L+
Sbjct: 138 GALAGTTAASLTYPLDLVRARMAV---------TPKEMYSNIFHVFIRISREEGLKTLYH 188
Query: 302 GLIPRLIKIAPACAIMISTYEFGKAFFQKQNVRRQQY 338
G +P ++ + P + TYE K+ ++ + RRQ Y
Sbjct: 189 GFMPTVLGVIPYAGLSFFTYETLKSLHREYSGRRQPY 225
Score = 42.4 bits (98), Expect = 6e-04
Identities = 24/90 (26%), Positives = 44/90 (48%), Gaps = 2/90 (2%)
Query: 84 FQGTLDAFFKIIRNEGIKSLWSGLPPTLVMAVPATVIYFTCYDQLSALLRSKLGENE--T 141
+ F +I R EG+K+L+ G PT++ +P + F Y+ L +L R G +
Sbjct: 167 YSNIFHVFIRISREEGLKTLYHGFMPTVLGVIPYAGLSFFTYETLKSLHREYSGRRQPYP 226
Query: 142 CIPIVAGIVARFGAVTVISPLELIRTKMQS 171
++ G A + PL+++R +MQ+
Sbjct: 227 FERMIFGACAGLIGQSASYPLDVVRRRMQT 256
>gi|239755176 PREDICTED: similar to solute carrier family 25, member
25 isoform 2 [Homo sapiens]
Length = 469
Score = 91.7 bits (226), Expect = 9e-19
Identities = 64/243 (26%), Positives = 118/243 (48%), Gaps = 9/243 (3%)
Query: 83 NFQGTLDAFFKIIRNEGIKSLWSGLPPTLVMAVPATVIYFTCYDQLSALLRSKLGENETC 142
N G + F ++IR G +SLW G ++ P + I F Y+Q+ L+ S
Sbjct: 222 NNMGIVGGFTQMIREGGARSLWRGNGINVLKIAPESAIKFMAYEQIKRLVGSDQETLRIH 281
Query: 143 IPIVAGIVARFGAVTVISPLELIRTKMQSKKF-SYVELHRFVSKKVSEDGWISLWRGWAP 201
+VAG +A A + I P+E+++T+M +K Y + + ++ +G + ++G+ P
Sbjct: 282 ERLVAGSLAGAIAQSSIYPMEVLKTRMALRKTGQYSGMLDCARRILAREGVAAFYKGYVP 341
Query: 202 TVLRDVPFSAMYWYNYEILKK-WLCEKS-GLYEPTFMINFTSGALSGSFAAVATLPFDVV 259
+L +P++ + YE LK WL + +P + G +S + +A+ P +V
Sbjct: 342 NMLGIIPYAGIDLAVYETLKNAWLQHYAVNSADPGVFVLLACGTMSSTCGQLASYPLALV 401
Query: 260 KTQKQTQLWTYESHKISMPLHMSTWIIMKNIVAKNGFSGLFSGLIPRLIKIAPACAIMIS 319
+T+ Q Q + +++M + K+I+ G GL+ GL P +K+ PA +I
Sbjct: 402 RTRMQAQASIEGAPEVTMS------SLFKHILRTEGAFGLYRGLAPNFMKVIPAVSISYV 455
Query: 320 TYE 322
YE
Sbjct: 456 VYE 458
Score = 50.1 bits (118), Expect = 3e-06
Identities = 35/151 (23%), Positives = 64/151 (42%), Gaps = 8/151 (5%)
Query: 79 KKPGNFQGTLDAFFKIIRNEGIKSLWSGLPPTLVMAVPATVIYFTCYDQLSALLRSKLGE 138
+K G + G LD +I+ EG+ + + G P ++ +P I Y+ L
Sbjct: 311 RKTGQYSGMLDCARRILAREGVAAFYKGYVPNMLGIIPYAGIDLAVYETLKNAWLQHYAV 370
Query: 139 NET----CIPIVAGIVARFGAVTVISPLELIRTKMQSKKF----SYVELHRFVSKKVSED 190
N + + G ++ PL L+RT+MQ++ V + + +
Sbjct: 371 NSADPGVFVLLACGTMSSTCGQLASYPLALVRTRMQAQASIEGAPEVTMSSLFKHILRTE 430
Query: 191 GWISLWRGWAPTVLRDVPFSAMYWYNYEILK 221
G L+RG AP ++ +P ++ + YE LK
Sbjct: 431 GAFGLYRGLAPNFMKVIPAVSISYVVYENLK 461
Score = 34.3 bits (77), Expect = 0.16
Identities = 17/47 (36%), Positives = 25/47 (53%), Gaps = 1/47 (2%)
Query: 87 TLDAFFK-IIRNEGIKSLWSGLPPTLVMAVPATVIYFTCYDQLSALL 132
T+ + FK I+R EG L+ GL P + +PA I + Y+ L L
Sbjct: 418 TMSSLFKHILRTEGAFGLYRGLAPNFMKVIPAVSISYVVYENLKITL 464
>gi|239755174 PREDICTED: similar to solute carrier family 25, member
25 isoform 1 [Homo sapiens]
Length = 503
Score = 91.7 bits (226), Expect = 9e-19
Identities = 64/243 (26%), Positives = 118/243 (48%), Gaps = 9/243 (3%)
Query: 83 NFQGTLDAFFKIIRNEGIKSLWSGLPPTLVMAVPATVIYFTCYDQLSALLRSKLGENETC 142
N G + F ++IR G +SLW G ++ P + I F Y+Q+ L+ S
Sbjct: 256 NNMGIVGGFTQMIREGGARSLWRGNGINVLKIAPESAIKFMAYEQIKRLVGSDQETLRIH 315
Query: 143 IPIVAGIVARFGAVTVISPLELIRTKMQSKKF-SYVELHRFVSKKVSEDGWISLWRGWAP 201
+VAG +A A + I P+E+++T+M +K Y + + ++ +G + ++G+ P
Sbjct: 316 ERLVAGSLAGAIAQSSIYPMEVLKTRMALRKTGQYSGMLDCARRILAREGVAAFYKGYVP 375
Query: 202 TVLRDVPFSAMYWYNYEILKK-WLCEKS-GLYEPTFMINFTSGALSGSFAAVATLPFDVV 259
+L +P++ + YE LK WL + +P + G +S + +A+ P +V
Sbjct: 376 NMLGIIPYAGIDLAVYETLKNAWLQHYAVNSADPGVFVLLACGTMSSTCGQLASYPLALV 435
Query: 260 KTQKQTQLWTYESHKISMPLHMSTWIIMKNIVAKNGFSGLFSGLIPRLIKIAPACAIMIS 319
+T+ Q Q + +++M + K+I+ G GL+ GL P +K+ PA +I
Sbjct: 436 RTRMQAQASIEGAPEVTMS------SLFKHILRTEGAFGLYRGLAPNFMKVIPAVSISYV 489
Query: 320 TYE 322
YE
Sbjct: 490 VYE 492
Score = 50.1 bits (118), Expect = 3e-06
Identities = 35/151 (23%), Positives = 64/151 (42%), Gaps = 8/151 (5%)
Query: 79 KKPGNFQGTLDAFFKIIRNEGIKSLWSGLPPTLVMAVPATVIYFTCYDQLSALLRSKLGE 138
+K G + G LD +I+ EG+ + + G P ++ +P I Y+ L
Sbjct: 345 RKTGQYSGMLDCARRILAREGVAAFYKGYVPNMLGIIPYAGIDLAVYETLKNAWLQHYAV 404
Query: 139 NET----CIPIVAGIVARFGAVTVISPLELIRTKMQSKKF----SYVELHRFVSKKVSED 190
N + + G ++ PL L+RT+MQ++ V + + +
Sbjct: 405 NSADPGVFVLLACGTMSSTCGQLASYPLALVRTRMQAQASIEGAPEVTMSSLFKHILRTE 464
Query: 191 GWISLWRGWAPTVLRDVPFSAMYWYNYEILK 221
G L+RG AP ++ +P ++ + YE LK
Sbjct: 465 GAFGLYRGLAPNFMKVIPAVSISYVVYENLK 495
Score = 34.3 bits (77), Expect = 0.16
Identities = 17/47 (36%), Positives = 25/47 (53%), Gaps = 1/47 (2%)
Query: 87 TLDAFFK-IIRNEGIKSLWSGLPPTLVMAVPATVIYFTCYDQLSALL 132
T+ + FK I+R EG L+ GL P + +PA I + Y+ L L
Sbjct: 452 TMSSLFKHILRTEGAFGLYRGLAPNFMKVIPAVSISYVVYENLKITL 498
>gi|56699407 solute carrier family 25, member 25 isoform c [Homo
sapiens]
Length = 489
Score = 91.7 bits (226), Expect = 9e-19
Identities = 64/243 (26%), Positives = 118/243 (48%), Gaps = 9/243 (3%)
Query: 83 NFQGTLDAFFKIIRNEGIKSLWSGLPPTLVMAVPATVIYFTCYDQLSALLRSKLGENETC 142
N G + F ++IR G +SLW G ++ P + I F Y+Q+ L+ S
Sbjct: 242 NNMGIVGGFTQMIREGGARSLWRGNGINVLKIAPESAIKFMAYEQIKRLVGSDQETLRIH 301
Query: 143 IPIVAGIVARFGAVTVISPLELIRTKMQSKKF-SYVELHRFVSKKVSEDGWISLWRGWAP 201
+VAG +A A + I P+E+++T+M +K Y + + ++ +G + ++G+ P
Sbjct: 302 ERLVAGSLAGAIAQSSIYPMEVLKTRMALRKTGQYSGMLDCARRILAREGVAAFYKGYVP 361
Query: 202 TVLRDVPFSAMYWYNYEILKK-WLCEKS-GLYEPTFMINFTSGALSGSFAAVATLPFDVV 259
+L +P++ + YE LK WL + +P + G +S + +A+ P +V
Sbjct: 362 NMLGIIPYAGIDLAVYETLKNAWLQHYAVNSADPGVFVLLACGTMSSTCGQLASYPLALV 421
Query: 260 KTQKQTQLWTYESHKISMPLHMSTWIIMKNIVAKNGFSGLFSGLIPRLIKIAPACAIMIS 319
+T+ Q Q + +++M + K+I+ G GL+ GL P +K+ PA +I
Sbjct: 422 RTRMQAQASIEGAPEVTMS------SLFKHILRTEGAFGLYRGLAPNFMKVIPAVSISYV 475
Query: 320 TYE 322
YE
Sbjct: 476 VYE 478
Score = 50.1 bits (118), Expect = 3e-06
Identities = 35/151 (23%), Positives = 64/151 (42%), Gaps = 8/151 (5%)
Query: 79 KKPGNFQGTLDAFFKIIRNEGIKSLWSGLPPTLVMAVPATVIYFTCYDQLSALLRSKLGE 138
+K G + G LD +I+ EG+ + + G P ++ +P I Y+ L
Sbjct: 331 RKTGQYSGMLDCARRILAREGVAAFYKGYVPNMLGIIPYAGIDLAVYETLKNAWLQHYAV 390
Query: 139 NET----CIPIVAGIVARFGAVTVISPLELIRTKMQSKKF----SYVELHRFVSKKVSED 190
N + + G ++ PL L+RT+MQ++ V + + +
Sbjct: 391 NSADPGVFVLLACGTMSSTCGQLASYPLALVRTRMQAQASIEGAPEVTMSSLFKHILRTE 450
Query: 191 GWISLWRGWAPTVLRDVPFSAMYWYNYEILK 221
G L+RG AP ++ +P ++ + YE LK
Sbjct: 451 GAFGLYRGLAPNFMKVIPAVSISYVVYENLK 481
Score = 34.3 bits (77), Expect = 0.16
Identities = 17/47 (36%), Positives = 25/47 (53%), Gaps = 1/47 (2%)
Query: 87 TLDAFFK-IIRNEGIKSLWSGLPPTLVMAVPATVIYFTCYDQLSALL 132
T+ + FK I+R EG L+ GL P + +PA I + Y+ L L
Sbjct: 438 TMSSLFKHILRTEGAFGLYRGLAPNFMKVIPAVSISYVVYENLKITL 484
>gi|56699401 solute carrier family 25, member 25 isoform a [Homo
sapiens]
Length = 469
Score = 91.7 bits (226), Expect = 9e-19
Identities = 64/243 (26%), Positives = 118/243 (48%), Gaps = 9/243 (3%)
Query: 83 NFQGTLDAFFKIIRNEGIKSLWSGLPPTLVMAVPATVIYFTCYDQLSALLRSKLGENETC 142
N G + F ++IR G +SLW G ++ P + I F Y+Q+ L+ S
Sbjct: 222 NNMGIVGGFTQMIREGGARSLWRGNGINVLKIAPESAIKFMAYEQIKRLVGSDQETLRIH 281
Query: 143 IPIVAGIVARFGAVTVISPLELIRTKMQSKKF-SYVELHRFVSKKVSEDGWISLWRGWAP 201
+VAG +A A + I P+E+++T+M +K Y + + ++ +G + ++G+ P
Sbjct: 282 ERLVAGSLAGAIAQSSIYPMEVLKTRMALRKTGQYSGMLDCARRILAREGVAAFYKGYVP 341
Query: 202 TVLRDVPFSAMYWYNYEILKK-WLCEKS-GLYEPTFMINFTSGALSGSFAAVATLPFDVV 259
+L +P++ + YE LK WL + +P + G +S + +A+ P +V
Sbjct: 342 NMLGIIPYAGIDLAVYETLKNAWLQHYAVNSADPGVFVLLACGTMSSTCGQLASYPLALV 401
Query: 260 KTQKQTQLWTYESHKISMPLHMSTWIIMKNIVAKNGFSGLFSGLIPRLIKIAPACAIMIS 319
+T+ Q Q + +++M + K+I+ G GL+ GL P +K+ PA +I
Sbjct: 402 RTRMQAQASIEGAPEVTMS------SLFKHILRTEGAFGLYRGLAPNFMKVIPAVSISYV 455
Query: 320 TYE 322
YE
Sbjct: 456 VYE 458
Score = 50.1 bits (118), Expect = 3e-06
Identities = 35/151 (23%), Positives = 64/151 (42%), Gaps = 8/151 (5%)
Query: 79 KKPGNFQGTLDAFFKIIRNEGIKSLWSGLPPTLVMAVPATVIYFTCYDQLSALLRSKLGE 138
+K G + G LD +I+ EG+ + + G P ++ +P I Y+ L
Sbjct: 311 RKTGQYSGMLDCARRILAREGVAAFYKGYVPNMLGIIPYAGIDLAVYETLKNAWLQHYAV 370
Query: 139 NET----CIPIVAGIVARFGAVTVISPLELIRTKMQSKKF----SYVELHRFVSKKVSED 190
N + + G ++ PL L+RT+MQ++ V + + +
Sbjct: 371 NSADPGVFVLLACGTMSSTCGQLASYPLALVRTRMQAQASIEGAPEVTMSSLFKHILRTE 430
Query: 191 GWISLWRGWAPTVLRDVPFSAMYWYNYEILK 221
G L+RG AP ++ +P ++ + YE LK
Sbjct: 431 GAFGLYRGLAPNFMKVIPAVSISYVVYENLK 461
Score = 34.3 bits (77), Expect = 0.16
Identities = 17/47 (36%), Positives = 25/47 (53%), Gaps = 1/47 (2%)
Query: 87 TLDAFFK-IIRNEGIKSLWSGLPPTLVMAVPATVIYFTCYDQLSALL 132
T+ + FK I+R EG L+ GL P + +PA I + Y+ L L
Sbjct: 418 TMSSLFKHILRTEGAFGLYRGLAPNFMKVIPAVSISYVVYENLKITL 464
>gi|56699405 solute carrier family 25, member 25 isoform d [Homo
sapiens]
Length = 366
Score = 91.7 bits (226), Expect = 9e-19
Identities = 64/243 (26%), Positives = 118/243 (48%), Gaps = 9/243 (3%)
Query: 83 NFQGTLDAFFKIIRNEGIKSLWSGLPPTLVMAVPATVIYFTCYDQLSALLRSKLGENETC 142
N G + F ++IR G +SLW G ++ P + I F Y+Q+ L+ S
Sbjct: 119 NNMGIVGGFTQMIREGGARSLWRGNGINVLKIAPESAIKFMAYEQIKRLVGSDQETLRIH 178
Query: 143 IPIVAGIVARFGAVTVISPLELIRTKMQSKKF-SYVELHRFVSKKVSEDGWISLWRGWAP 201
+VAG +A A + I P+E+++T+M +K Y + + ++ +G + ++G+ P
Sbjct: 179 ERLVAGSLAGAIAQSSIYPMEVLKTRMALRKTGQYSGMLDCARRILAREGVAAFYKGYVP 238
Query: 202 TVLRDVPFSAMYWYNYEILKK-WLCEKS-GLYEPTFMINFTSGALSGSFAAVATLPFDVV 259
+L +P++ + YE LK WL + +P + G +S + +A+ P +V
Sbjct: 239 NMLGIIPYAGIDLAVYETLKNAWLQHYAVNSADPGVFVLLACGTMSSTCGQLASYPLALV 298
Query: 260 KTQKQTQLWTYESHKISMPLHMSTWIIMKNIVAKNGFSGLFSGLIPRLIKIAPACAIMIS 319
+T+ Q Q + +++M + K+I+ G GL+ GL P +K+ PA +I
Sbjct: 299 RTRMQAQASIEGAPEVTMS------SLFKHILRTEGAFGLYRGLAPNFMKVIPAVSISYV 352
Query: 320 TYE 322
YE
Sbjct: 353 VYE 355
Score = 50.1 bits (118), Expect = 3e-06
Identities = 35/151 (23%), Positives = 64/151 (42%), Gaps = 8/151 (5%)
Query: 79 KKPGNFQGTLDAFFKIIRNEGIKSLWSGLPPTLVMAVPATVIYFTCYDQLSALLRSKLGE 138
+K G + G LD +I+ EG+ + + G P ++ +P I Y+ L
Sbjct: 208 RKTGQYSGMLDCARRILAREGVAAFYKGYVPNMLGIIPYAGIDLAVYETLKNAWLQHYAV 267
Query: 139 NET----CIPIVAGIVARFGAVTVISPLELIRTKMQSKKF----SYVELHRFVSKKVSED 190
N + + G ++ PL L+RT+MQ++ V + + +
Sbjct: 268 NSADPGVFVLLACGTMSSTCGQLASYPLALVRTRMQAQASIEGAPEVTMSSLFKHILRTE 327
Query: 191 GWISLWRGWAPTVLRDVPFSAMYWYNYEILK 221
G L+RG AP ++ +P ++ + YE LK
Sbjct: 328 GAFGLYRGLAPNFMKVIPAVSISYVVYENLK 358
Score = 34.3 bits (77), Expect = 0.16
Identities = 17/47 (36%), Positives = 25/47 (53%), Gaps = 1/47 (2%)
Query: 87 TLDAFFK-IIRNEGIKSLWSGLPPTLVMAVPATVIYFTCYDQLSALL 132
T+ + FK I+R EG L+ GL P + +PA I + Y+ L L
Sbjct: 315 TMSSLFKHILRTEGAFGLYRGLAPNFMKVIPAVSISYVVYENLKITL 361
>gi|56699403 solute carrier family 25, member 25 isoform b [Homo
sapiens]
Length = 503
Score = 91.7 bits (226), Expect = 9e-19
Identities = 64/243 (26%), Positives = 118/243 (48%), Gaps = 9/243 (3%)
Query: 83 NFQGTLDAFFKIIRNEGIKSLWSGLPPTLVMAVPATVIYFTCYDQLSALLRSKLGENETC 142
N G + F ++IR G +SLW G ++ P + I F Y+Q+ L+ S
Sbjct: 256 NNMGIVGGFTQMIREGGARSLWRGNGINVLKIAPESAIKFMAYEQIKRLVGSDQETLRIH 315
Query: 143 IPIVAGIVARFGAVTVISPLELIRTKMQSKKF-SYVELHRFVSKKVSEDGWISLWRGWAP 201
+VAG +A A + I P+E+++T+M +K Y + + ++ +G + ++G+ P
Sbjct: 316 ERLVAGSLAGAIAQSSIYPMEVLKTRMALRKTGQYSGMLDCARRILAREGVAAFYKGYVP 375
Query: 202 TVLRDVPFSAMYWYNYEILKK-WLCEKS-GLYEPTFMINFTSGALSGSFAAVATLPFDVV 259
+L +P++ + YE LK WL + +P + G +S + +A+ P +V
Sbjct: 376 NMLGIIPYAGIDLAVYETLKNAWLQHYAVNSADPGVFVLLACGTMSSTCGQLASYPLALV 435
Query: 260 KTQKQTQLWTYESHKISMPLHMSTWIIMKNIVAKNGFSGLFSGLIPRLIKIAPACAIMIS 319
+T+ Q Q + +++M + K+I+ G GL+ GL P +K+ PA +I
Sbjct: 436 RTRMQAQASIEGAPEVTMS------SLFKHILRTEGAFGLYRGLAPNFMKVIPAVSISYV 489
Query: 320 TYE 322
YE
Sbjct: 490 VYE 492
Score = 50.1 bits (118), Expect = 3e-06
Identities = 35/151 (23%), Positives = 64/151 (42%), Gaps = 8/151 (5%)
Query: 79 KKPGNFQGTLDAFFKIIRNEGIKSLWSGLPPTLVMAVPATVIYFTCYDQLSALLRSKLGE 138
+K G + G LD +I+ EG+ + + G P ++ +P I Y+ L
Sbjct: 345 RKTGQYSGMLDCARRILAREGVAAFYKGYVPNMLGIIPYAGIDLAVYETLKNAWLQHYAV 404
Query: 139 NET----CIPIVAGIVARFGAVTVISPLELIRTKMQSKKF----SYVELHRFVSKKVSED 190
N + + G ++ PL L+RT+MQ++ V + + +
Sbjct: 405 NSADPGVFVLLACGTMSSTCGQLASYPLALVRTRMQAQASIEGAPEVTMSSLFKHILRTE 464
Query: 191 GWISLWRGWAPTVLRDVPFSAMYWYNYEILK 221
G L+RG AP ++ +P ++ + YE LK
Sbjct: 465 GAFGLYRGLAPNFMKVIPAVSISYVVYENLK 495
Score = 34.3 bits (77), Expect = 0.16
Identities = 17/47 (36%), Positives = 25/47 (53%), Gaps = 1/47 (2%)
Query: 87 TLDAFFK-IIRNEGIKSLWSGLPPTLVMAVPATVIYFTCYDQLSALL 132
T+ + FK I+R EG L+ GL P + +PA I + Y+ L L
Sbjct: 452 TMSSLFKHILRTEGAFGLYRGLAPNFMKVIPAVSISYVVYENLKITL 498
>gi|13449279 solute carrier family 25 (mitochondrial
oxodicarboxylate carrier), member 21 [Homo sapiens]
Length = 299
Score = 89.4 bits (220), Expect = 4e-18
Identities = 72/320 (22%), Positives = 145/320 (45%), Gaps = 43/320 (13%)
Query: 17 QQMLASCTGAILTSVIVTPLDVVKIRLQAQNNPLPKGKCFVYSNGLMDHLCVCEEGGNKL 76
+Q++A + ++ ++ PLDVVK R Q Q C +
Sbjct: 15 RQIVAGGSAGLVEICLMHPLDVVKTRFQIQR-------------------CATD------ 49
Query: 77 WYKKPGNFQGTLDAFFKIIRNEGIKSLWSGLPPTLVMAVPATVIYFTCYDQLSALLRSKL 136
P +++ +D+F I + EG+ + G+ P ++ P + F ++Q LL +
Sbjct: 50 ----PNSYKSLVDSFRMIFQMEGLFGFYKGILPPILAETPKRAVKFFTFEQYKKLL-GYV 104
Query: 137 GENETCIPIVAGIVARFGAVTVISPLELIRTKMQSKKFSYVELHRFVS---KKVSEDGW- 192
+ +AG+ + V++P E+++ +Q+ + ++ E V + + ++GW
Sbjct: 105 SLSPALTFAIAGLGSGLTEAIVVNPFEVVKVGLQANRNTFAEQPSTVGYARQIIKKEGWG 164
Query: 193 -ISLWRGWAPTVLRDVPFSAMYWYNYEILKKWL-CEKSGLYEPTFMINFTSGALSGSFAA 250
L +G T+ R F+ +Y+ Y +K + K + E F F G LSG+ A+
Sbjct: 165 LQGLNKGLTATLGRHGVFNMVYFGFYYNVKNMIPVNKDPILE--FWRKFGIGLLSGTIAS 222
Query: 251 VATLPFDVVKTQKQTQLWTYESHKISMPLHMSTWIIMKNIVAKNGFSGLFSGLIPRLIKI 310
V +PFDV K++ Q K + + + M + + G L+ GL+P+++++
Sbjct: 223 VINIPFDVAKSRIQGPQPVPGEIK-----YRTCFKTMATVYQEEGILALYKGLLPKIMRL 277
Query: 311 APACAIMISTYEFGKAFFQK 330
P A+M+ YE+ ++ Q+
Sbjct: 278 GPGGAVMLLVYEYTYSWLQE 297
>gi|82775373 solute carrier family 25, member 37 [Homo sapiens]
Length = 338
Score = 89.0 bits (219), Expect = 6e-18
Identities = 82/324 (25%), Positives = 135/324 (41%), Gaps = 43/324 (13%)
Query: 19 MLASCTGAILTSVIVTPLDVVKIRLQAQNNPLPKGKCFVYSNGLMDHLCVCEEGGNKLWY 78
M A IL ++ P+D VK R+Q+ + P PK +
Sbjct: 49 MTAGAMAGILEHSVMYPVDSVKTRMQSLS-PDPKAQ------------------------ 83
Query: 79 KKPGNFQGTLDAFFKIIRNEGIKSLWSGLPPTLVMAVPATVIYFTCYDQLSALLRSKLGE 138
+ A KI+R EG G+ ++ A PA +YF CY+ + L
Sbjct: 84 -----YTSIYGALKKIMRTEGFWRPLRGVNVMIMGAGPAHAMYFACYENMKRTLNDVFHH 138
Query: 139 --NETCIPIVAGIVARFGAVTVISPLELIRTKMQSKKFSYVELHRFVSKKVSEDGWISLW 196
N +AG +A V++P E+++ ++Q + + +G + +
Sbjct: 139 QGNSHLANGIAGSMATLLHDAVMNPAEVVKQRLQMYNSQHRSAISCIRTVWRTEGLGAFY 198
Query: 197 RGWAPTVLRDVPFSAMYWYNYEILKKWLCEKSGLYEPTFMINFTSGALSGSFAAVATLPF 256
R + + ++PF ++++ YE L++ + Y P I SG L+G+ AA AT P
Sbjct: 199 RSYTTQLTMNIPFQSIHFITYEFLQEQV-NPHRTYNPQSHI--ISGGLAGALAAAATTPL 255
Query: 257 DVVKTQKQTQLWTYESHKISMPLHMSTWIIMKN----IVAKNGFSGLFSGLIPRLIKIAP 312
DV KT TQ E+ +S+ M N + NG +G F G+ R+I P
Sbjct: 256 DVCKTLLNTQ----ENVALSLANISGRLSGMANAFRTVYQLNGLAGYFKGIQARVIYQMP 311
Query: 313 ACAIMISTYEFGKAFFQKQNVRRQ 336
+ AI S YEF K F K+ + +
Sbjct: 312 STAISWSVYEFFKYFLTKRQLENR 335
>gi|149274607 solute carrier family 25, member 41 [Homo sapiens]
Length = 370
Score = 88.2 bits (217), Expect = 1e-17
Identities = 61/247 (24%), Positives = 123/247 (49%), Gaps = 9/247 (3%)
Query: 78 YKKPGNFQGTLDAFFKIIRNEGIKSLWSGLPPTLVMAVPATVIYFTCYDQLSALLRSKLG 137
Y NF L +++ G +SLW G ++ P I F+ ++Q G
Sbjct: 123 YSSKTNFTNLLGGLQSMVQEGGFRSLWRGNGINVLKIAPEYAIKFSVFEQCKNYFCGIQG 182
Query: 138 ENETCIPIVAGIVARFGAVTVISPLELIRTKMQSKKFS-YVELHRFVSKKVSEDGWISLW 196
++AG +A + T+I+P+E+++T++ ++ Y L + + +G +L+
Sbjct: 183 SPPFQERLLAGSLAVAISQTLINPMEVLKTRLTLRRTGQYKGLLDCARQILQREGTRALY 242
Query: 197 RGWAPTVLRDVPFSAMYWYNYEILKK-WLCEKSGLYEPTFMINFTSGALSGSFAAVATLP 255
RG+ P +L +P++ YE+L+ W+ + +P+ +++ +S LS + +A+ P
Sbjct: 243 RGYLPNMLGIIPYACTDLAVYEMLQCFWVKSGRDMGDPSGLVSLSSVTLSTTCGQMASYP 302
Query: 256 FDVVKTQKQTQLWTYESHKISMPLHMSTWIIMKNIVAKNGFSGLFSGLIPRLIKIAPACA 315
+V+T+ Q Q ++ + S P +++ I+A+ G+ GL+ G+ P L+K+ PA
Sbjct: 303 LTLVRTRMQAQ----DTVEGSNPTMRG---VLQRILAQQGWLGLYRGMTPTLLKVLPAGG 355
Query: 316 IMISTYE 322
I YE
Sbjct: 356 ISYVVYE 362
Score = 64.3 bits (155), Expect = 1e-10
Identities = 37/156 (23%), Positives = 78/156 (50%), Gaps = 6/156 (3%)
Query: 75 KLWYKKPGNFQGTLDAFFKIIRNEGIKSLWSGLPPTLVMAVPATVIYFTCYDQLSALLRS 134
+L ++ G ++G LD +I++ EG ++L+ G P ++ +P Y+ L
Sbjct: 213 RLTLRRTGQYKGLLDCARQILQREGTRALYRGYLPNMLGIIPYACTDLAVYEMLQCFWVK 272
Query: 135 K---LGENETCIPIVAGIVARFGAVTVISPLELIRTKMQSK---KFSYVELHRFVSKKVS 188
+G+ + + + ++ PL L+RT+MQ++ + S + + + ++
Sbjct: 273 SGRDMGDPSGLVSLSSVTLSTTCGQMASYPLTLVRTRMQAQDTVEGSNPTMRGVLQRILA 332
Query: 189 EDGWISLWRGWAPTVLRDVPFSAMYWYNYEILKKWL 224
+ GW+ L+RG PT+L+ +P + + YE +KK L
Sbjct: 333 QQGWLGLYRGMTPTLLKVLPAGGISYVVYEAMKKTL 368
Score = 57.4 bits (137), Expect = 2e-08
Identities = 47/187 (25%), Positives = 82/187 (43%), Gaps = 17/187 (9%)
Query: 146 VAGIVARFGAVTVISPLELIRTKMQ--SKKFSYVELHRFVSKKVSEDGWISLWRGWAPTV 203
+AG V+R G +PL+ + MQ S K ++ L + V E G+ SLWRG V
Sbjct: 101 MAGAVSRTGT----APLDRAKVYMQVYSSKTNFTNLLGGLQSMVQEGGFRSLWRGNGINV 156
Query: 204 LRDVPFSAMYWYNYEILKKWLCEKSGLYEPTFMINFTSGALSGSFAAVATLPFDVVKTQK 263
L+ P A+ + +E K + C G P F +G+L+ + + P +V+KT+
Sbjct: 157 LKIAPEYAIKFSVFEQCKNYFCGIQG--SPPFQERLLAGSLAVAISQTLINPMEVLKTRL 214
Query: 264 QTQLWTYESHKISMPLHMSTWIIMKNIVAKNGFSGLFSGLIPRLIKIAPACAIMISTYEF 323
+ + + I+ + G L+ G +P ++ I P ++ YE
Sbjct: 215 TLR---------RTGQYKGLLDCARQILQREGTRALYRGYLPNMLGIIPYACTDLAVYEM 265
Query: 324 GKAFFQK 330
+ F+ K
Sbjct: 266 LQCFWVK 272
Score = 35.4 bits (80), Expect = 0.073
Identities = 26/88 (29%), Positives = 42/88 (47%), Gaps = 8/88 (9%)
Query: 241 SGALSGSFAAVATLPFDVVKTQKQTQLWTYESHKISMPLHMSTWIIMKNIVAKNGFSGLF 300
SGA++G+ + T P D K Q S K + + ++++V + GF L+
Sbjct: 98 SGAMAGAVSRTGTAPLDRAKVYMQVY-----SSKTNFTNLLGG---LQSMVQEGGFRSLW 149
Query: 301 SGLIPRLIKIAPACAIMISTYEFGKAFF 328
G ++KIAP AI S +E K +F
Sbjct: 150 RGNGINVLKIAPEYAIKFSVFEQCKNYF 177
>gi|4507009 solute carrier family 25, member 14 isoform UCP5L [Homo
sapiens]
Length = 325
Score = 87.0 bits (214), Expect = 2e-17
Identities = 65/241 (26%), Positives = 111/241 (46%), Gaps = 8/241 (3%)
Query: 84 FQGTLDAFFKIIRNEGIKSLWSGLPPTLVMAVPATVIYFTCYDQLSALLRSKLGENETCI 143
++G A F+I + EG+ +L+SG+ P L+ I Y L L +L + I
Sbjct: 84 YRGMFHALFRICKEEGVLALYSGIAPALLRQASYGTIKIGIYQSLKRLFVERLEDETLLI 143
Query: 144 PIVAGIVARFGAVTVISPLELIRTKMQSK--KFSYVELHRFVSKKVSEDGWISLWRGWAP 201
++ G+V+ + T+ +P ++++ +MQ++ F + F+ ++G LWRG P
Sbjct: 144 NMICGVVSGVISSTIANPTDVLKIRMQAQGSLFQGSMIGSFID-IYQQEGTRGLWRGVVP 202
Query: 202 TVLRDVPFSAMYWYNYEILKKWLCEKSGLYEPTFMINFTSGALSGSFAAVATLPFDVVKT 261
T R + Y+I KK L SG+ T + +F S G A+A+ P DVV+T
Sbjct: 203 TAQRAAIVVGVELPVYDITKKHLI-LSGMMGDTILTHFVSSFTCGLAGALASNPVDVVRT 261
Query: 262 QKQTQLWTYESHKISMPLHMSTWIIMKNIVAKNGFSGLFSGLIPRLIKIAPACAIMISTY 321
+ Q H + L+ T + + GF L+ G P +++ P I TY
Sbjct: 262 RMMNQR-AIVGH---VDLYKGTVDGILKMWKHEGFFALYKGFWPNWLRLGPWNIIFFITY 317
Query: 322 E 322
E
Sbjct: 318 E 318
Score = 63.2 bits (152), Expect = 3e-10
Identities = 50/217 (23%), Positives = 94/217 (43%), Gaps = 42/217 (19%)
Query: 14 TPLQQMLASCTGAILTSVIVTPLDVVKIRLQAQNNPLPKGKCFVYSNGLMDHLCVCEEGG 73
T L M+ +++S I P DV+KIR+QAQ +
Sbjct: 140 TLLINMICGVVSGVISSTIANPTDVLKIRMQAQGSL------------------------ 175
Query: 74 NKLWYKKPGNFQGTL-DAFFKIIRNEGIKSLWSGLPPTLVMAVPATVIYFTCYDQLSA-L 131
FQG++ +F I + EG + LW G+ PT A + YD L
Sbjct: 176 ----------FQGSMIGSFIDIYQQEGTRGLWRGVVPTAQRAAIVVGVELPVYDITKKHL 225
Query: 132 LRSKLGENETCIPIVAGIVARFGAVTVISPLELIRTKMQSKK--FSYVELHRF----VSK 185
+ S + + V+ +P++++RT+M +++ +V+L++ + K
Sbjct: 226 ILSGMMGDTILTHFVSSFTCGLAGALASNPVDVVRTRMMNQRAIVGHVDLYKGTVDGILK 285
Query: 186 KVSEDGWISLWRGWAPTVLRDVPFSAMYWYNYEILKK 222
+G+ +L++G+ P LR P++ +++ YE LK+
Sbjct: 286 MWKHEGFFALYKGFWPNWLRLGPWNIIFFITYEQLKR 322
Score = 61.6 bits (148), Expect = 1e-09
Identities = 47/189 (24%), Positives = 86/189 (45%), Gaps = 24/189 (12%)
Query: 146 VAGIVARFGAVTVISPLELIRTKMQS---------KKFSYVELHRFVSKKVSEDGWISLW 196
+A IVA FG P++L +T++Q K+ Y + + + E+G ++L+
Sbjct: 49 LASIVAEFGTF----PVDLTKTRLQVQGQSIDARFKEIKYRGMFHALFRICKEEGVLALY 104
Query: 197 RGWAPTVLRDVPFSAMYWYNYEILKKWLCEKSGLYEPTFMINFTSGALSGSFAAVATLPF 256
G AP +LR + + Y+ LK+ E+ L + T +IN G +SG ++ P
Sbjct: 105 SGIAPALLRQASYGTIKIGIYQSLKRLFVER--LEDETLLINMICGVVSGVISSTIANPT 162
Query: 257 DVVKTQKQTQLWTYESHKISMPLHMSTWIIMKNIVAKNGFSGLFSGLIPRLIKIAPACAI 316
DV+K + Q Q ++ I + +I + G GL+ G++P + A +
Sbjct: 163 DVLKIRMQAQGSLFQGSMIGSFI---------DIYQQEGTRGLWRGVVPTAQRAAIVVGV 213
Query: 317 MISTYEFGK 325
+ Y+ K
Sbjct: 214 ELPVYDITK 222
Score = 37.7 bits (86), Expect = 0.015
Identities = 27/118 (22%), Positives = 51/118 (43%), Gaps = 28/118 (23%)
Query: 14 TPLQQMLASCTGAILTSVIVTPLDVVKIRLQAQNNPLPKGKCFVYSNGLMDHLCVCEEGG 73
T L ++S T + ++ P+DVV+ R+ Q ++ H+ +
Sbjct: 234 TILTHFVSSFTCGLAGALASNPVDVVRTRMMNQR-------------AIVGHVDL----- 275
Query: 74 NKLWYKKPGNFQGTLDAFFKIIRNEGIKSLWSGLPPTLVMAVPATVIYFTCYDQLSAL 131
++GT+D K+ ++EG +L+ G P + P +I+F Y+QL L
Sbjct: 276 ----------YKGTVDGILKMWKHEGFFALYKGFWPNWLRLGPWNIIFFITYEQLKRL 323
Score = 35.0 bits (79), Expect = 0.096
Identities = 24/90 (26%), Positives = 40/90 (44%), Gaps = 1/90 (1%)
Query: 239 FTSGALSGSFAAVATLPFDVVKTQKQTQLWTYESHKISMPLHMSTWIIMKNIVAKNGFSG 298
F G L+ A T P D+ KT+ Q Q + ++ + + + + I + G
Sbjct: 44 FVYGGLASIVAEFGTFPVDLTKTRLQVQGQSIDA-RFKEIKYRGMFHALFRICKEEGVLA 102
Query: 299 LFSGLIPRLIKIAPACAIMISTYEFGKAFF 328
L+SG+ P L++ A I I Y+ K F
Sbjct: 103 LYSGIAPALLRQASYGTIKIGIYQSLKRLF 132
>gi|13259543 solute carrier family 25, member 14 isoform UCP5S [Homo
sapiens]
Length = 322
Score = 87.0 bits (214), Expect = 2e-17
Identities = 65/241 (26%), Positives = 111/241 (46%), Gaps = 8/241 (3%)
Query: 84 FQGTLDAFFKIIRNEGIKSLWSGLPPTLVMAVPATVIYFTCYDQLSALLRSKLGENETCI 143
++G A F+I + EG+ +L+SG+ P L+ I Y L L +L + I
Sbjct: 81 YRGMFHALFRICKEEGVLALYSGIAPALLRQASYGTIKIGIYQSLKRLFVERLEDETLLI 140
Query: 144 PIVAGIVARFGAVTVISPLELIRTKMQSK--KFSYVELHRFVSKKVSEDGWISLWRGWAP 201
++ G+V+ + T+ +P ++++ +MQ++ F + F+ ++G LWRG P
Sbjct: 141 NMICGVVSGVISSTIANPTDVLKIRMQAQGSLFQGSMIGSFID-IYQQEGTRGLWRGVVP 199
Query: 202 TVLRDVPFSAMYWYNYEILKKWLCEKSGLYEPTFMINFTSGALSGSFAAVATLPFDVVKT 261
T R + Y+I KK L SG+ T + +F S G A+A+ P DVV+T
Sbjct: 200 TAQRAAIVVGVELPVYDITKKHLI-LSGMMGDTILTHFVSSFTCGLAGALASNPVDVVRT 258
Query: 262 QKQTQLWTYESHKISMPLHMSTWIIMKNIVAKNGFSGLFSGLIPRLIKIAPACAIMISTY 321
+ Q H + L+ T + + GF L+ G P +++ P I TY
Sbjct: 259 RMMNQR-AIVGH---VDLYKGTVDGILKMWKHEGFFALYKGFWPNWLRLGPWNIIFFITY 314
Query: 322 E 322
E
Sbjct: 315 E 315
Score = 63.2 bits (152), Expect = 3e-10
Identities = 50/217 (23%), Positives = 94/217 (43%), Gaps = 42/217 (19%)
Query: 14 TPLQQMLASCTGAILTSVIVTPLDVVKIRLQAQNNPLPKGKCFVYSNGLMDHLCVCEEGG 73
T L M+ +++S I P DV+KIR+QAQ +
Sbjct: 137 TLLINMICGVVSGVISSTIANPTDVLKIRMQAQGSL------------------------ 172
Query: 74 NKLWYKKPGNFQGTL-DAFFKIIRNEGIKSLWSGLPPTLVMAVPATVIYFTCYDQLSA-L 131
FQG++ +F I + EG + LW G+ PT A + YD L
Sbjct: 173 ----------FQGSMIGSFIDIYQQEGTRGLWRGVVPTAQRAAIVVGVELPVYDITKKHL 222
Query: 132 LRSKLGENETCIPIVAGIVARFGAVTVISPLELIRTKMQSKK--FSYVELHRF----VSK 185
+ S + + V+ +P++++RT+M +++ +V+L++ + K
Sbjct: 223 ILSGMMGDTILTHFVSSFTCGLAGALASNPVDVVRTRMMNQRAIVGHVDLYKGTVDGILK 282
Query: 186 KVSEDGWISLWRGWAPTVLRDVPFSAMYWYNYEILKK 222
+G+ +L++G+ P LR P++ +++ YE LK+
Sbjct: 283 MWKHEGFFALYKGFWPNWLRLGPWNIIFFITYEQLKR 319
Score = 61.6 bits (148), Expect = 1e-09
Identities = 47/189 (24%), Positives = 86/189 (45%), Gaps = 24/189 (12%)
Query: 146 VAGIVARFGAVTVISPLELIRTKMQS---------KKFSYVELHRFVSKKVSEDGWISLW 196
+A IVA FG P++L +T++Q K+ Y + + + E+G ++L+
Sbjct: 46 LASIVAEFGTF----PVDLTKTRLQVQGQSIDARFKEIKYRGMFHALFRICKEEGVLALY 101
Query: 197 RGWAPTVLRDVPFSAMYWYNYEILKKWLCEKSGLYEPTFMINFTSGALSGSFAAVATLPF 256
G AP +LR + + Y+ LK+ E+ L + T +IN G +SG ++ P
Sbjct: 102 SGIAPALLRQASYGTIKIGIYQSLKRLFVER--LEDETLLINMICGVVSGVISSTIANPT 159
Query: 257 DVVKTQKQTQLWTYESHKISMPLHMSTWIIMKNIVAKNGFSGLFSGLIPRLIKIAPACAI 316
DV+K + Q Q ++ I + +I + G GL+ G++P + A +
Sbjct: 160 DVLKIRMQAQGSLFQGSMIGSFI---------DIYQQEGTRGLWRGVVPTAQRAAIVVGV 210
Query: 317 MISTYEFGK 325
+ Y+ K
Sbjct: 211 ELPVYDITK 219
Score = 37.7 bits (86), Expect = 0.015
Identities = 27/118 (22%), Positives = 51/118 (43%), Gaps = 28/118 (23%)
Query: 14 TPLQQMLASCTGAILTSVIVTPLDVVKIRLQAQNNPLPKGKCFVYSNGLMDHLCVCEEGG 73
T L ++S T + ++ P+DVV+ R+ Q ++ H+ +
Sbjct: 231 TILTHFVSSFTCGLAGALASNPVDVVRTRMMNQR-------------AIVGHVDL----- 272
Query: 74 NKLWYKKPGNFQGTLDAFFKIIRNEGIKSLWSGLPPTLVMAVPATVIYFTCYDQLSAL 131
++GT+D K+ ++EG +L+ G P + P +I+F Y+QL L
Sbjct: 273 ----------YKGTVDGILKMWKHEGFFALYKGFWPNWLRLGPWNIIFFITYEQLKRL 320
Score = 35.0 bits (79), Expect = 0.096
Identities = 24/90 (26%), Positives = 40/90 (44%), Gaps = 1/90 (1%)
Query: 239 FTSGALSGSFAAVATLPFDVVKTQKQTQLWTYESHKISMPLHMSTWIIMKNIVAKNGFSG 298
F G L+ A T P D+ KT+ Q Q + ++ + + + + I + G
Sbjct: 41 FVYGGLASIVAEFGTFPVDLTKTRLQVQGQSIDA-RFKEIKYRGMFHALFRICKEEGVLA 99
Query: 299 LFSGLIPRLIKIAPACAIMISTYEFGKAFF 328
L+SG+ P L++ A I I Y+ K F
Sbjct: 100 LYSGIAPALLRQASYGTIKIGIYQSLKRLF 129
>gi|7657581 solute carrier family 25, member 13 isoform 2 [Homo
sapiens]
Length = 675
Score = 86.7 bits (213), Expect = 3e-17
Identities = 79/309 (25%), Positives = 130/309 (42%), Gaps = 35/309 (11%)
Query: 20 LASCTGAILTSVIVTPLDVVKIRLQAQNNPLPKGKCFVYSNGLMDHLCVCEEGGNKLWYK 79
L S GA+ + V P+D+VK R+Q Q + FV +L YK
Sbjct: 334 LGSVAGAV-GATAVYPIDLVKTRMQNQRST----GSFV----------------GELMYK 372
Query: 80 KPGNFQGTLDAFFKIIRNEGIKSLWSGLPPTLVMAVPATVIYFTCYDQLSALLRSKLGEN 139
+ D F K++R EG L+ GL P L+ P I T D + K G
Sbjct: 373 ------NSFDCFKKVLRYEGFFGLYRGLLPQLLGVAPEKAIKLTVNDFVRDKFMHKDGSV 426
Query: 140 ETCIPIVAGIVARFGAVTVISPLELIRTKMQSKKFSYVELHRFVSKKVSEDGWISLWRGW 199
I+AG A V +PLE+++ ++Q V + G+ +++G
Sbjct: 427 PLAAEILAGGCAGGSQVIFTNPLEIVKIRLQVAGEITTGPRVSALSVVRDLGFFGIYKGA 486
Query: 200 APTVLRDVPFSAMYWYNYEILKKWLCEKSGLYEPTFMINFTSGALSGSFAAVATLPFDVV 259
LRD+PFSA+Y+ Y +K + G P ++ +GA++G AA P DV+
Sbjct: 487 KACFLRDIPFSAIYFPCYAHVKASFANEDGQVSPGSLL--LAGAIAGMPAASLVTPADVI 544
Query: 260 KTQKQTQLWTYESHKISMPLHMSTWIIMKNIVAKNGFSGLFSGLIPRLIKIAPACAIMIS 319
KT+ Q + + + + I+ + G L+ G R+ + +P + +
Sbjct: 545 KTRLQV------AARAGQTTYSGVIDCFRKILREEGPKALWKGAGARVFRSSPQFGVTLL 598
Query: 320 TYEFGKAFF 328
TYE + +F
Sbjct: 599 TYELLQRWF 607
Score = 62.0 bits (149), Expect = 7e-10
Identities = 35/144 (24%), Positives = 72/144 (50%), Gaps = 4/144 (2%)
Query: 94 IIRNEGIKSLWSGLPPTLVMAVPATVIYFTCYDQLSALLRSKLGENETCIPIVAGIVARF 153
++R+ G ++ G + +P + IYF CY + A ++ G+ ++AG +A
Sbjct: 473 VVRDLGFFGIYKGAKACFLRDIPFSAIYFPCYAHVKASFANEDGQVSPGSLLLAGAIAGM 532
Query: 154 GAVTVISPLELIRTKMQ----SKKFSYVELHRFVSKKVSEDGWISLWRGWAPTVLRDVPF 209
A ++++P ++I+T++Q + + +Y + K + E+G +LW+G V R P
Sbjct: 533 PAASLVTPADVIKTRLQVAARAGQTTYSGVIDCFRKILREEGPKALWKGAGARVFRSSPQ 592
Query: 210 SAMYWYNYEILKKWLCEKSGLYEP 233
+ YE+L++W G +P
Sbjct: 593 FGVTLLTYELLQRWFYIDFGGVKP 616
Score = 52.4 bits (124), Expect = 6e-07
Identities = 28/94 (29%), Positives = 53/94 (56%), Gaps = 2/94 (2%)
Query: 239 FTSGALSGSFAAVATLPFDVVKTQKQTQLWTYESHKISMPLHMSTWIIMKNIVAKNGFSG 298
F G+++G+ A A P D+VKT+ Q Q T + ++ +++ K ++ GF G
Sbjct: 332 FGLGSVAGAVGATAVYPIDLVKTRMQNQRST--GSFVGELMYKNSFDCFKKVLRYEGFFG 389
Query: 299 LFSGLIPRLIKIAPACAIMISTYEFGKAFFQKQN 332
L+ GL+P+L+ +AP AI ++ +F + F ++
Sbjct: 390 LYRGLLPQLLGVAPEKAIKLTVNDFVRDKFMHKD 423
Score = 46.2 bits (108), Expect = 4e-05
Identities = 41/193 (21%), Positives = 80/193 (41%), Gaps = 20/193 (10%)
Query: 148 GIVARFGAVTVISPLELIRTKMQSKK--------FSYVELHRFVSKKVSEDGWISLWRGW 199
G VA T + P++L++T+MQ+++ Y K + +G+ L+RG
Sbjct: 335 GSVAGAVGATAVYPIDLVKTRMQNQRSTGSFVGELMYKNSFDCFKKVLRYEGFFGLYRGL 394
Query: 200 APTVLRDVPFSAMYWYNYEILKKWLCEKSGLYEPTFMINFTSGALSGSFAAVATLPFDVV 259
P +L P A+ + ++ K G +G +G + T P ++V
Sbjct: 395 LPQLLGVAPEKAIKLTVNDFVRDKFMHKDG--SVPLAAEILAGGCAGGSQVIFTNPLEIV 452
Query: 260 KTQKQTQLWTYESHKISMPLHMSTWIIMKNIVAKNGFSGLFSGLIPRLIKIAPACAIMIS 319
K + Q + +I+ +S +++++ GF G++ G ++ P AI
Sbjct: 453 KIRLQV------AGEITTGPRVSALSVVRDL----GFFGIYKGAKACFLRDIPFSAIYFP 502
Query: 320 TYEFGKAFFQKQN 332
Y KA F ++
Sbjct: 503 CYAHVKASFANED 515
Score = 40.0 bits (92), Expect = 0.003
Identities = 30/117 (25%), Positives = 45/117 (38%), Gaps = 30/117 (25%)
Query: 12 KVTPLQQMLASCTGAILTSVIVTPLDVVKIRLQAQNNPLPKGKCFVYSNGLMDHLCVCEE 71
+V+P +LA + + +VTP DV+K RLQ V
Sbjct: 517 QVSPGSLLLAGAIAGMPAASLVTPADVIKTRLQ-----------------------VAAR 553
Query: 72 GGNKLWYKKPGNFQGTLDAFFKIIRNEGIKSLWSGLPPTLVMAVPATVIYFTCYDQL 128
G + G +D F KI+R EG K+LW G + + P + Y+ L
Sbjct: 554 AGQT-------TYSGVIDCFRKILREEGPKALWKGAGARVFRSSPQFGVTLLTYELL 603
>gi|237649019 solute carrier family 25, member 13 isoform 1 [Homo
sapiens]
Length = 676
Score = 86.7 bits (213), Expect = 3e-17
Identities = 79/309 (25%), Positives = 130/309 (42%), Gaps = 35/309 (11%)
Query: 20 LASCTGAILTSVIVTPLDVVKIRLQAQNNPLPKGKCFVYSNGLMDHLCVCEEGGNKLWYK 79
L S GA+ + V P+D+VK R+Q Q + FV +L YK
Sbjct: 335 LGSVAGAV-GATAVYPIDLVKTRMQNQRST----GSFV----------------GELMYK 373
Query: 80 KPGNFQGTLDAFFKIIRNEGIKSLWSGLPPTLVMAVPATVIYFTCYDQLSALLRSKLGEN 139
+ D F K++R EG L+ GL P L+ P I T D + K G
Sbjct: 374 ------NSFDCFKKVLRYEGFFGLYRGLLPQLLGVAPEKAIKLTVNDFVRDKFMHKDGSV 427
Query: 140 ETCIPIVAGIVARFGAVTVISPLELIRTKMQSKKFSYVELHRFVSKKVSEDGWISLWRGW 199
I+AG A V +PLE+++ ++Q V + G+ +++G
Sbjct: 428 PLAAEILAGGCAGGSQVIFTNPLEIVKIRLQVAGEITTGPRVSALSVVRDLGFFGIYKGA 487
Query: 200 APTVLRDVPFSAMYWYNYEILKKWLCEKSGLYEPTFMINFTSGALSGSFAAVATLPFDVV 259
LRD+PFSA+Y+ Y +K + G P ++ +GA++G AA P DV+
Sbjct: 488 KACFLRDIPFSAIYFPCYAHVKASFANEDGQVSPGSLL--LAGAIAGMPAASLVTPADVI 545
Query: 260 KTQKQTQLWTYESHKISMPLHMSTWIIMKNIVAKNGFSGLFSGLIPRLIKIAPACAIMIS 319
KT+ Q + + + + I+ + G L+ G R+ + +P + +
Sbjct: 546 KTRLQV------AARAGQTTYSGVIDCFRKILREEGPKALWKGAGARVFRSSPQFGVTLL 599
Query: 320 TYEFGKAFF 328
TYE + +F
Sbjct: 600 TYELLQRWF 608
Score = 62.0 bits (149), Expect = 7e-10
Identities = 35/144 (24%), Positives = 72/144 (50%), Gaps = 4/144 (2%)
Query: 94 IIRNEGIKSLWSGLPPTLVMAVPATVIYFTCYDQLSALLRSKLGENETCIPIVAGIVARF 153
++R+ G ++ G + +P + IYF CY + A ++ G+ ++AG +A
Sbjct: 474 VVRDLGFFGIYKGAKACFLRDIPFSAIYFPCYAHVKASFANEDGQVSPGSLLLAGAIAGM 533
Query: 154 GAVTVISPLELIRTKMQ----SKKFSYVELHRFVSKKVSEDGWISLWRGWAPTVLRDVPF 209
A ++++P ++I+T++Q + + +Y + K + E+G +LW+G V R P
Sbjct: 534 PAASLVTPADVIKTRLQVAARAGQTTYSGVIDCFRKILREEGPKALWKGAGARVFRSSPQ 593
Query: 210 SAMYWYNYEILKKWLCEKSGLYEP 233
+ YE+L++W G +P
Sbjct: 594 FGVTLLTYELLQRWFYIDFGGVKP 617
Score = 52.4 bits (124), Expect = 6e-07
Identities = 28/94 (29%), Positives = 53/94 (56%), Gaps = 2/94 (2%)
Query: 239 FTSGALSGSFAAVATLPFDVVKTQKQTQLWTYESHKISMPLHMSTWIIMKNIVAKNGFSG 298
F G+++G+ A A P D+VKT+ Q Q T + ++ +++ K ++ GF G
Sbjct: 333 FGLGSVAGAVGATAVYPIDLVKTRMQNQRST--GSFVGELMYKNSFDCFKKVLRYEGFFG 390
Query: 299 LFSGLIPRLIKIAPACAIMISTYEFGKAFFQKQN 332
L+ GL+P+L+ +AP AI ++ +F + F ++
Sbjct: 391 LYRGLLPQLLGVAPEKAIKLTVNDFVRDKFMHKD 424
Score = 46.2 bits (108), Expect = 4e-05
Identities = 41/193 (21%), Positives = 80/193 (41%), Gaps = 20/193 (10%)
Query: 148 GIVARFGAVTVISPLELIRTKMQSKK--------FSYVELHRFVSKKVSEDGWISLWRGW 199
G VA T + P++L++T+MQ+++ Y K + +G+ L+RG
Sbjct: 336 GSVAGAVGATAVYPIDLVKTRMQNQRSTGSFVGELMYKNSFDCFKKVLRYEGFFGLYRGL 395
Query: 200 APTVLRDVPFSAMYWYNYEILKKWLCEKSGLYEPTFMINFTSGALSGSFAAVATLPFDVV 259
P +L P A+ + ++ K G +G +G + T P ++V
Sbjct: 396 LPQLLGVAPEKAIKLTVNDFVRDKFMHKDG--SVPLAAEILAGGCAGGSQVIFTNPLEIV 453
Query: 260 KTQKQTQLWTYESHKISMPLHMSTWIIMKNIVAKNGFSGLFSGLIPRLIKIAPACAIMIS 319
K + Q + +I+ +S +++++ GF G++ G ++ P AI
Sbjct: 454 KIRLQV------AGEITTGPRVSALSVVRDL----GFFGIYKGAKACFLRDIPFSAIYFP 503
Query: 320 TYEFGKAFFQKQN 332
Y KA F ++
Sbjct: 504 CYAHVKASFANED 516
Score = 40.0 bits (92), Expect = 0.003
Identities = 30/117 (25%), Positives = 45/117 (38%), Gaps = 30/117 (25%)
Query: 12 KVTPLQQMLASCTGAILTSVIVTPLDVVKIRLQAQNNPLPKGKCFVYSNGLMDHLCVCEE 71
+V+P +LA + + +VTP DV+K RLQ V
Sbjct: 518 QVSPGSLLLAGAIAGMPAASLVTPADVIKTRLQ-----------------------VAAR 554
Query: 72 GGNKLWYKKPGNFQGTLDAFFKIIRNEGIKSLWSGLPPTLVMAVPATVIYFTCYDQL 128
G + G +D F KI+R EG K+LW G + + P + Y+ L
Sbjct: 555 AGQT-------TYSGVIDCFRKILREEGPKALWKGAGARVFRSSPQFGVTLLTYELL 604
>gi|27544933 solute carrier family 25, member 16 [Homo sapiens]
Length = 332
Score = 85.1 bits (209), Expect = 8e-17
Identities = 80/330 (24%), Positives = 132/330 (40%), Gaps = 54/330 (16%)
Query: 16 LQQMLASCTGAILTSVIVTPLDVVKIRLQAQNNPLPKGKCFVYSNGLMDHLCVCEEGGNK 75
L+ LA V PLD VK+ LQA N+
Sbjct: 37 LRSFLAGGIAGCCAKTTVAPLDRVKVLLQAHNHH-------------------------- 70
Query: 76 LWYKKPGNFQGTLDAFFKIIRNEGIKSLWSGLPPTLVMAVPATVIYFTCYDQLSALLRSK 135
YK G F A + + EG L+ G ++ P I F ++ L+ +K
Sbjct: 71 --YKHLGVFS----ALRAVPQKEGFLGLYKGNGAMMIRIFPYGAIQFMAFEHYKTLITTK 124
Query: 136 LGENETCIPIVAGIVARFGAVTVISPLELIRTKMQSK---KFSYVE-LHRFVSKKVSEDG 191
LG + ++AG +A AV PL+++R ++ + + SY +H F + E G
Sbjct: 125 LGISGHVHRLMAGSMAGMTAVICTYPLDMVRVRLAFQVKGEHSYTGIIHAFKTIYAKEGG 184
Query: 192 WISLWRGWAPTVLRDVPFSAMYWYNYEILKK-------WLCEKSGLYEPTFM-----INF 239
+ +RG PT+L P++ + ++ + LK L + P + +N
Sbjct: 185 FFGFYRGLMPTILGMAPYAGVSFFTFGTLKSVGLSHAPTLLGRPSSDNPNVLVLKTHVNL 244
Query: 240 TSGALSGSFAAVATLPFDVVKTQKQTQLWTYESHKISMPLHMSTWIIMKNIVAKNGF-SG 298
G ++G+ A + PFDV + + Q E K ++ MK + +G G
Sbjct: 245 LCGGVAGAIAQTISYPFDVTRRRMQLGTVLPEFEKC-----LTMRDTMKYVYGHHGIRKG 299
Query: 299 LFSGLIPRLIKIAPACAIMISTYEFGKAFF 328
L+ GL I+ P+ A+ +TYE K FF
Sbjct: 300 LYRGLSLNYIRCIPSQAVAFTTYELMKQFF 329
>gi|157388989 solute carrier family 25, member 36 isoform a [Homo
sapiens]
Length = 311
Score = 83.6 bits (205), Expect = 2e-16
Identities = 80/322 (24%), Positives = 139/322 (43%), Gaps = 40/322 (12%)
Query: 16 LQQMLASCTGAILTSVIVTPLDVVKIRLQAQNNPLPKGKCFVYSNGLMDHLCVCEEGGNK 75
L + A G + +++ PL+VVK RLQ+ + L + V N + G +
Sbjct: 7 LVHLFAGGCGGTVGAILTCPLEVVKTRLQSSSVTLYISE--VQLNTMA--------GASV 56
Query: 76 LWYKKPGNFQGTLDAFFKIIRNEGIKSLWSGLPPTLVMAVPATVIYFTCYDQLSALLRSK 135
PG L I+ EG +SL+ GL P LV P+ IYF Y L
Sbjct: 57 NRVVSPG----PLHCLKVILEKEGPRSLFRGLGPNLVGVAPSRAIYFAAYSNCKEKLNDV 112
Query: 136 LGENETCIPIVAGIVARFGAVTVISPLELIRTKMQ----SKKFSYVELHRFVSKKVSEDG 191
+ T + +++ +A F A+T +P+ LI+T++Q ++ + V K DG
Sbjct: 113 FDPDSTQVHMISAAMAGFTAITATNPIWLIKTRLQLDARNRGERRMGAFECVRKVYQTDG 172
Query: 192 WISLWRGWAPTVLRDVPFSAMYWYNYEILKKWLC-----------EKSGLYEPTFMINFT 240
+RG + + + + +++ YE +K+ L E+S F+
Sbjct: 173 LKGFYRGMSAS-YAGISETVIHFVIYESIKQKLLEYKTASTMENDEESVKEASDFVGMML 231
Query: 241 SGALSGSFAAVATLPFDVVKTQKQTQLWTYESHKISMPLHMSTWIIMKNIVAKNGFSGLF 300
+ A S + A P +VV+T+ + + Y S ++ L +V + G+ L+
Sbjct: 232 AAATSKTCATTIAYPHEVVRTRLREEGTKYRSFFQTLSL----------LVQEEGYGSLY 281
Query: 301 SGLIPRLIKIAPACAIMISTYE 322
GL L++ P AIM++TYE
Sbjct: 282 RGLTTHLVRQIPNTAIMMATYE 303
Score = 54.7 bits (130), Expect = 1e-07
Identities = 34/148 (22%), Positives = 72/148 (48%), Gaps = 14/148 (9%)
Query: 86 GTLDAFFKIIRNEGIKSLWSGLPPTLVMAVPATVIYFTCYDQLSALL-----RSKLGENE 140
G + K+ + +G+K + G+ + + TVI+F Y+ + L S + +E
Sbjct: 159 GAFECVRKVYQTDGLKGFYRGMSASYA-GISETVIHFVIYESIKQKLLEYKTASTMENDE 217
Query: 141 TCIP--------IVAGIVARFGAVTVISPLELIRTKMQSKKFSYVELHRFVSKKVSEDGW 192
+ ++A ++ A T+ P E++RT+++ + Y + +S V E+G+
Sbjct: 218 ESVKEASDFVGMMLAAATSKTCATTIAYPHEVVRTRLREEGTKYRSFFQTLSLLVQEEGY 277
Query: 193 ISLWRGWAPTVLRDVPFSAMYWYNYEIL 220
SL+RG ++R +P +A+ YE++
Sbjct: 278 GSLYRGLTTHLVRQIPNTAIMMATYELV 305
Score = 45.1 bits (105), Expect = 9e-05
Identities = 40/189 (21%), Positives = 82/189 (43%), Gaps = 30/189 (15%)
Query: 136 LGENETCIPIVAGIVARFGAVTVISPLELIRTKMQSKK----FSYVELHRFVSKKVS--- 188
+ + +T + + AG + PLE+++T++QS S V+L+ V+
Sbjct: 1 MSQRDTLVHLFAGGCGGTVGAILTCPLEVVKTRLQSSSVTLYISEVQLNTMAGASVNRVV 60
Query: 189 -------------EDGWISLWRGWAPTVLRDVPFSAMYWYNYEILKKWLCEKSGLYEP-T 234
++G SL+RG P ++ P A+Y+ Y K+ L + +++P +
Sbjct: 61 SPGPLHCLKVILEKEGPRSLFRGLGPNLVGVAPSRAIYFAAYSNCKEKL---NDVFDPDS 117
Query: 235 FMINFTSGALSGSFAAVATLPFDVVKTQKQTQLWTYESHKISMPLHMSTWIIMKNIVAKN 294
++ S A++G A AT P ++KT+ Q + M + ++ + +
Sbjct: 118 TQVHMISAAMAGFTAITATNPIWLIKTRLQLDARNRGERR------MGAFECVRKVYQTD 171
Query: 295 GFSGLFSGL 303
G G + G+
Sbjct: 172 GLKGFYRGM 180
>gi|4557403 carnitine/acylcarnitine translocase [Homo sapiens]
Length = 301
Score = 83.6 bits (205), Expect = 2e-16
Identities = 80/325 (24%), Positives = 134/325 (41%), Gaps = 49/325 (15%)
Query: 13 VTPLQQMLASCTGAILTSVIVTPLDVVKIRLQAQNNPLPKGKCFVYSNGLMDHLCVCEEG 72
++PL+ +LA G + + PLD VK+RLQ Q LP
Sbjct: 8 ISPLKNLLAGGFGGVCLVFVGHPLDTVKVRLQTQPPSLP--------------------- 46
Query: 73 GNKLWYKKPGNFQGTLDAFFKIIRNEGIKSLWSGLPPTLVMAVPATVIYFTCYDQLSALL 132
+P + GT D F K + EGI L+ G+ ++ P + F + L L
Sbjct: 47 ------GQPPMYSGTFDCFRKTLFREGITGLYRGMAAPIIGVTPMFAVCFFGFG-LGKKL 99
Query: 133 RSKLGENETCIP--IVAGIVARFGAVTVISPLELIRTKMQ----SKKFSYVELHRFVSKK 186
+ K E+ P AG+++ +++P E I+ +Q S + Y K
Sbjct: 100 QQKHPEDVLSYPQLFAAGMLSGVFTTGIMTPGERIKCLLQIQASSGESKYTGTLDCAKKL 159
Query: 187 VSEDGWISLWRGWAPTVLRDVPFSAMYWYNYEILKKWLCEK----SGLYEPTFMINFTSG 242
E G +++G T++RDVP S MY+ YE LK + S L P ++ +G
Sbjct: 160 YQEFGIRGIYKGTVLTLMRDVPASGMYFMTYEWLKNIFTPEGKRVSELSAPRILV---AG 216
Query: 243 ALSGSFAAVATLPFDVVKTQKQTQLWTYESHKISMPLHMSTWIIMKNIVAKNGFSGLFSG 302
++G F +P DV+K++ QT + P +++ ++ G + L+ G
Sbjct: 217 GIAGIFNWAVAIPPDVLKSRFQT------APPGKYPNGFRD--VLRELIRDEGVTSLYKG 268
Query: 303 LIPRLIKIAPACAIMISTYEFGKAF 327
+I+ PA A +E F
Sbjct: 269 FNAVMIRAFPANAACFLGFEVAMKF 293
Score = 52.8 bits (125), Expect = 4e-07
Identities = 38/146 (26%), Positives = 75/146 (51%), Gaps = 5/146 (3%)
Query: 84 FQGTLDAFFKIIRNEGIKSLWSGLPPTLVMAVPATVIYFTCYDQLSALLR---SKLGENE 140
+ GTLD K+ + GI+ ++ G TL+ VPA+ +YF Y+ L + ++ E
Sbjct: 149 YTGTLDCAKKLYQEFGIRGIYKGTVLTLMRDVPASGMYFMTYEWLKNIFTPEGKRVSELS 208
Query: 141 TCIPIVAGIVARFGAVTVISPLELIRTKMQ-SKKFSYVELHRFVSKK-VSEDGWISLWRG 198
+VAG +A V P ++++++ Q + Y R V ++ + ++G SL++G
Sbjct: 209 APRILVAGGIAGIFNWAVAIPPDVLKSRFQTAPPGKYPNGFRDVLRELIRDEGVTSLYKG 268
Query: 199 WAPTVLRDVPFSAMYWYNYEILKKWL 224
+ ++R P +A + +E+ K+L
Sbjct: 269 FNAVMIRAFPANAACFLGFEVAMKFL 294
Score = 50.1 bits (118), Expect = 3e-06
Identities = 47/201 (23%), Positives = 86/201 (42%), Gaps = 17/201 (8%)
Query: 144 PIVAGIVARFGAVTVI---SPLELIRTKMQSKKFS-------YVELHRFVSKKVSEDGWI 193
P+ + FG V ++ PL+ ++ ++Q++ S Y K + +G
Sbjct: 10 PLKNLLAGGFGGVCLVFVGHPLDTVKVRLQTQPPSLPGQPPMYSGTFDCFRKTLFREGIT 69
Query: 194 SLWRGWAPTVLRDVPFSAMYWYNYEILKKWLCEKSGLYEPTFMINFTSGALSGSFAAVAT 253
L+RG A ++ P A+ ++ + + KK L +K ++ F +G LSG F
Sbjct: 70 GLYRGMAAPIIGVTPMFAVCFFGFGLGKK-LQQKHPEDVLSYPQLFAAGMLSGVFTTGIM 128
Query: 254 LPFDVVKTQKQTQLWTYESHKISMPLHMSTWIIMKNIVAKNGFSGLFSGLIPRLIKIAPA 313
P + +K Q Q + ES + T K + + G G++ G + L++ PA
Sbjct: 129 TPGERIKCLLQIQASSGESK------YTGTLDCAKKLYQEFGIRGIYKGTVLTLMRDVPA 182
Query: 314 CAIMISTYEFGKAFFQKQNVR 334
+ TYE+ K F + R
Sbjct: 183 SGMYFMTYEWLKNIFTPEGKR 203
>gi|21361103 solute carrier family 25, member 12 [Homo sapiens]
Length = 678
Score = 82.4 bits (202), Expect = 5e-16
Identities = 76/313 (24%), Positives = 132/313 (42%), Gaps = 43/313 (13%)
Query: 20 LASCTGAILTSVIVTPLDVVKIRLQAQNNPLPKGKCFVYSNGLMDHLCVCEEGGNKLWYK 79
L S GA+ + V P+D+VK R+Q Q S ++ L
Sbjct: 332 LGSVAGAV-GATAVYPIDLVKTRMQNQRG----------SGSVVGELM------------ 368
Query: 80 KPGNFQGTLDAFFKIIRNEGIKSLWSGLPPTLVMAVPATVIYFTCYDQLSALLRSKLGEN 139
++ + D F K++R EG L+ GL P L+ P I T D +R K
Sbjct: 369 ----YKNSFDCFKKVLRYEGFFGLYRGLIPQLIGVAPEKAIKLTVND----FVRDKFTRR 420
Query: 140 ETCIP----IVAGIVARFGAVTVISPLELIRTKMQSKKFSYVELHRFVSKKVSEDGWISL 195
+ +P ++AG A V +PLE+++ ++Q + + G L
Sbjct: 421 DGSVPLPAEVLAGGCAGGSQVIFTNPLEIVKIRLQVAGEITTGPRVSALNVLRDLGIFGL 480
Query: 196 WRGWAPTVLRDVPFSAMYWYNYEILKKWLCEKSGLYEPTFMINFTSGALSGSFAAVATLP 255
++G LRD+PFSA+Y+ Y K L +++G ++ +GA++G AA P
Sbjct: 481 YKGAKACFLRDIPFSAIYFPVYAHCKLLLADENGHVGGLNLL--AAGAMAGVPAASLVTP 538
Query: 256 FDVVKTQKQTQLWTYESHKISMPLHMSTWIIMKNIVAKNGFSGLFSGLIPRLIKIAPACA 315
DV+KT+ Q + + + + I+ + G S + G R+ + +P
Sbjct: 539 ADVIKTRLQV------AARAGQTTYSGVIDCFRKILREEGPSAFWKGTAARVFRSSPQFG 592
Query: 316 IMISTYEFGKAFF 328
+ + TYE + +F
Sbjct: 593 VTLVTYELLQRWF 605
Score = 59.3 bits (142), Expect = 5e-09
Identities = 52/224 (23%), Positives = 90/224 (40%), Gaps = 41/224 (18%)
Query: 15 PLQQMLASCTGAILTSVIVT-PLDVVKIRLQAQNNPLPKGKCFVYSNGLMDHLCVCEEGG 73
P + + C G + VI T PL++VKIRLQ
Sbjct: 427 PAEVLAGGCAGG--SQVIFTNPLEIVKIRLQVAGEITT---------------------- 462
Query: 74 NKLWYKKPGNFQGTLDAFFKIIRNEGIKSLWSGLPPTLVMAVPATVIYFTCYDQLSALLR 133
G + ++R+ GI L+ G + +P + IYF Y LL
Sbjct: 463 ------------GPRVSALNVLRDLGIFGLYKGAKACFLRDIPFSAIYFPVYAHCKLLLA 510
Query: 134 SKLGENETCIPIVAGIVARFGAVTVISPLELIRTKMQ----SKKFSYVELHRFVSKKVSE 189
+ G + AG +A A ++++P ++I+T++Q + + +Y + K + E
Sbjct: 511 DENGHVGGLNLLAAGAMAGVPAASLVTPADVIKTRLQVAARAGQTTYSGVIDCFRKILRE 570
Query: 190 DGWISLWRGWAPTVLRDVPFSAMYWYNYEILKKWLCEKSGLYEP 233
+G + W+G A V R P + YE+L++W G +P
Sbjct: 571 EGPSAFWKGTAARVFRSSPQFGVTLVTYELLQRWFYIDFGGLKP 614
Score = 56.6 bits (135), Expect = 3e-08
Identities = 30/94 (31%), Positives = 55/94 (58%), Gaps = 2/94 (2%)
Query: 239 FTSGALSGSFAAVATLPFDVVKTQKQTQLWTYESHKISMPLHMSTWIIMKNIVAKNGFSG 298
FT G+++G+ A A P D+VKT+ Q Q + + ++ +++ K ++ GF G
Sbjct: 330 FTLGSVAGAVGATAVYPIDLVKTRMQNQRGS--GSVVGELMYKNSFDCFKKVLRYEGFFG 387
Query: 299 LFSGLIPRLIKIAPACAIMISTYEFGKAFFQKQN 332
L+ GLIP+LI +AP AI ++ +F + F +++
Sbjct: 388 LYRGLIPQLIGVAPEKAIKLTVNDFVRDKFTRRD 421
Score = 42.0 bits (97), Expect = 8e-04
Identities = 39/201 (19%), Positives = 76/201 (37%), Gaps = 20/201 (9%)
Query: 140 ETCIPIVAGIVARFGAVTVISPLELIRTKMQSKKFS--------YVELHRFVSKKVSEDG 191
E+ G VA T + P++L++T+MQ+++ S Y K + +G
Sbjct: 325 ESAYRFTLGSVAGAVGATAVYPIDLVKTRMQNQRGSGSVVGELMYKNSFDCFKKVLRYEG 384
Query: 192 WISLWRGWAPTVLRDVPFSAMYWYNYEILKKWLCEKSGLYEPTFMINFTSGALSGSFAAV 251
+ L+RG P ++ P A+ + ++ + G +G +G +
Sbjct: 385 FFGLYRGLIPQLIGVAPEKAIKLTVNDFVRDKFTRRDG--SVPLPAEVLAGGCAGGSQVI 442
Query: 252 ATLPFDVVKTQKQTQLWTYESHKISMPLHMSTWIIMKNIVAKNGFSGLFSGLIPRLIKIA 311
T P ++VK + Q ++ + + N++ G GL+ G ++
Sbjct: 443 FTNPLEIVKIRLQ----------VAGEITTGPRVSALNVLRDLGIFGLYKGAKACFLRDI 492
Query: 312 PACAIMISTYEFGKAFFQKQN 332
P AI Y K +N
Sbjct: 493 PFSAIYFPVYAHCKLLLADEN 513
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.323 0.137 0.428
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 12,680,877
Number of Sequences: 37866
Number of extensions: 540963
Number of successful extensions: 1576
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 64
Number of HSP's successfully gapped in prelim test: 4
Number of HSP's that attempted gapping in prelim test: 1004
Number of HSP's gapped (non-prelim): 290
length of query: 338
length of database: 18,247,518
effective HSP length: 103
effective length of query: 235
effective length of database: 14,347,320
effective search space: 3371620200
effective search space used: 3371620200
T: 11
A: 40
X1: 16 ( 7.5 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (22.0 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.