Search of human proteins with 46048469

Search of human proteins with 46048469

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|46048469 major facilitator superfamily domain containing
6-like [Homo sapiens]
         (586 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|46048469 major facilitator superfamily domain containing 6-li...  1175   0.0  
gi|144953907 major facilitator superfamily domain containing 6 [...    95   2e-19
gi|94721311 hippocampus abundant transcript-like 1 [Homo sapiens]      35   0.19 
gi|39753965 hippocampus abundant transcript 1 [Homo sapiens]           34   0.33 
gi|117190342 PHD finger protein 2 [Homo sapiens]                       32   1.6  
gi|239750595 PREDICTED: similar to hCG2012058 [Homo sapiens]           31   3.6  
gi|74048554 cancer susceptibility candidate 5 isoform 2 [Homo sa...    30   4.7  
gi|74048514 cancer susceptibility candidate 5 isoform 1 [Homo sa...    30   4.7  
gi|157412273 surfactant associated 3 [Homo sapiens]                    30   4.7  
gi|38488720 DiGeorge syndrome critical region gene 8 [Homo sapiens]    30   6.2  
gi|149274653 patched domain containing 2 [Homo sapiens]                30   6.2  
gi|169172306 PREDICTED: hypothetical protein LOC441239 [Homo sap...    30   8.1  
gi|169170482 PREDICTED: hypothetical protein LOC441239 [Homo sap...    30   8.1  

>gi|46048469 major facilitator superfamily domain containing 6-like
           [Homo sapiens]
          Length = 586

 Score = 1175 bits (3039), Expect = 0.0
 Identities = 586/586 (100%), Positives = 586/586 (100%)

Query: 1   MSANPRWDISRALGVAKLFHLVCGVREACVTPFLTLYLRQLGLAAPWVGTLMGTKHLIAA 60
           MSANPRWDISRALGVAKLFHLVCGVREACVTPFLTLYLRQLGLAAPWVGTLMGTKHLIAA
Sbjct: 1   MSANPRWDISRALGVAKLFHLVCGVREACVTPFLTLYLRQLGLAAPWVGTLMGTKHLIAA 60

Query: 61  FWAPVCAFLAKSYRKRRALLIGSLLGSVGASLLMVLVPPVDKNRVHFPCNGSSGLTSTDA 120
           FWAPVCAFLAKSYRKRRALLIGSLLGSVGASLLMVLVPPVDKNRVHFPCNGSSGLTSTDA
Sbjct: 61  FWAPVCAFLAKSYRKRRALLIGSLLGSVGASLLMVLVPPVDKNRVHFPCNGSSGLTSTDA 120

Query: 121 LPGVTLPVNITSAQESASSHPAKRTAEVEMPGFRNPPGESDRETFRDLHVYLAPSVEGAR 180
           LPGVTLPVNITSAQESASSHPAKRTAEVEMPGFRNPPGESDRETFRDLHVYLAPSVEGAR
Sbjct: 121 LPGVTLPVNITSAQESASSHPAKRTAEVEMPGFRNPPGESDRETFRDLHVYLAPSVEGAR 180

Query: 181 TTSQALLHPVTSGLKDHPWEVTFEVVKTALPLLTGGKGPGNPANLSGTKGKAWAFDLSLE 240
           TTSQALLHPVTSGLKDHPWEVTFEVVKTALPLLTGGKGPGNPANLSGTKGKAWAFDLSLE
Sbjct: 181 TTSQALLHPVTSGLKDHPWEVTFEVVKTALPLLTGGKGPGNPANLSGTKGKAWAFDLSLE 240

Query: 241 ALRRTFILSLGSVAFWELLTAPLEQVADDSLYEFLDFVDATDRYRSLWVWRLLGMSAGVC 300
           ALRRTFILSLGSVAFWELLTAPLEQVADDSLYEFLDFVDATDRYRSLWVWRLLGMSAGVC
Sbjct: 241 ALRRTFILSLGSVAFWELLTAPLEQVADDSLYEFLDFVDATDRYRSLWVWRLLGMSAGVC 300

Query: 301 GITALVGQLDCFLMTSGPRGVVHFYGYSVVSTLALLVSIAFPIPICQQWEPSYKRVKALS 360
           GITALVGQLDCFLMTSGPRGVVHFYGYSVVSTLALLVSIAFPIPICQQWEPSYKRVKALS
Sbjct: 301 GITALVGQLDCFLMTSGPRGVVHFYGYSVVSTLALLVSIAFPIPICQQWEPSYKRVKALS 360

Query: 361 IVGGDPHLILLASTTVLVGAIVSTVQNFLFWHMKDHGSGELVMGFSVALSLLGEILLHPF 420
           IVGGDPHLILLASTTVLVGAIVSTVQNFLFWHMKDHGSGELVMGFSVALSLLGEILLHPF
Sbjct: 361 IVGGDPHLILLASTTVLVGAIVSTVQNFLFWHMKDHGSGELVMGFSVALSLLGEILLHPF 420

Query: 421 KATLLRKLSRTGLVGLGLSCLAGQLLYYSFLWSWWSVLPIQILSAISNRALWWAVGASVE 480
           KATLLRKLSRTGLVGLGLSCLAGQLLYYSFLWSWWSVLPIQILSAISNRALWWAVGASVE
Sbjct: 421 KATLLRKLSRTGLVGLGLSCLAGQLLYYSFLWSWWSVLPIQILSAISNRALWWAVGASVE 480

Query: 481 DLATPRMERALSALFRGHFYGSGCSLGSFVGGFVVMRFSLAVLYQACCVALLLWLALLLS 540
           DLATPRMERALSALFRGHFYGSGCSLGSFVGGFVVMRFSLAVLYQACCVALLLWLALLLS
Sbjct: 481 DLATPRMERALSALFRGHFYGSGCSLGSFVGGFVVMRFSLAVLYQACCVALLLWLALLLS 540

Query: 541 IQRRLPRERKIKYSKLLSMEVSDTSDSEQGTEQDWLVKAMREEHSD 586
           IQRRLPRERKIKYSKLLSMEVSDTSDSEQGTEQDWLVKAMREEHSD
Sbjct: 541 IQRRLPRERKIKYSKLLSMEVSDTSDSEQGTEQDWLVKAMREEHSD 586


>gi|144953907 major facilitator superfamily domain containing 6
           [Homo sapiens]
          Length = 791

 Score = 95.1 bits (235), Expect = 2e-19
 Identities = 127/587 (21%), Positives = 232/587 (39%), Gaps = 83/587 (14%)

Query: 9   ISRALGVAKLFHLVCGVREACVTPFLTLYLRQLGLAAPWVGTLMGTKHLIAAFWAPVCAF 68
           I+  L ++K+F+         + P L +Y +QLG++    G L+G ++ I    AP    
Sbjct: 64  INNDLLISKVFYFFFYSAYGSLYPLLPVYYKQLGMSPSQSGLLVGIRYFIEFCSAPFWGV 123

Query: 69  LAKSYRKRRALLIGSLLGSVGASLLMVLVPP-----VDKNR-VHFPCNGSSGLTSTDALP 122
           +A  ++K + +L+ SLL  V  +L +  V P     V K R    P N S  LT      
Sbjct: 124 VADRFKKGKIVLLFSLLCWVLFNLGIGFVKPATLRCVPKIRPTTHPTNASHQLT------ 177

Query: 123 GVTLPVNITSAQESASSHPAKRTAEVEMPGFRNPPGESDRETFRDLHVYLAPSVEGARTT 182
              LP N        SS  +  T   +M   RN   E+       + +  AP++      
Sbjct: 178 --ILPTN--------SSFTSFLTISPKMREKRNLL-ETRLNVSDTVTLPTAPNMN----- 221

Query: 183 SQALLHPVTSGLKDHPWEVTFEVVKTALPLLTGGKGPGNPANLSGTKGKAWAFDLSL--- 239
           S+  L P T  + +   ++T     TA P+  G         +  T     +  + L   
Sbjct: 222 SEPTLQPQTGEITNRMMDLTLNS-STATPVSPGSVTKETTTVIVTTTKSLPSDQVMLVYD 280

Query: 240 -EALRRTFILSLGSVAFWELLTAPLEQVADDSLYEFLDFVDATDRYRSLWVWRLLGMSAG 298
            + +   F++ L  V   E  +A    + D    ++L      DRY    +W  LG    
Sbjct: 281 QQEVEAIFLVILVVVIIGEFFSASSVTIVDTVTLQYLG--KHRDRYGLQRMWGSLGWGLA 338

Query: 299 VCGITALVGQLDCFLMTSGP--------RGVVHFYGYSVVSTLALLVSIAF--------- 341
           +  +   +      ++  G            + F  + V+ T+AL+V+  F         
Sbjct: 339 MLSVGIGIDYTHIEVLIDGKGCKPPEYRNYQIVFIVFGVLMTMALIVATQFRFRYNHFKN 398

Query: 342 --------PIPICQQWEPSYKRVKALSIVGGDPHL----ILLASTTVLVGAIVST----- 384
                    IP  ++   +    +  +            ++    +V  G+++       
Sbjct: 399 DDSKGKEVEIPQVERNNSTESSEETPTTTSHSQAFNFWDLIKLLCSVQYGSVLFVAWFMG 458

Query: 385 -----VQNFLFWHMKDHGSGELVMGFSVALSLLGEILLHPFKATLLRKLSRTGLVGLGLS 439
                V  FL+WH++D      + G    LS + E+  + F   L+  +    ++ +GL+
Sbjct: 459 FGYGFVFTFLYWHLEDLNGTTTLFGVCSVLSHVSELTAYFFSHKLIELIGHIRVLYIGLA 518

Query: 440 CLAGQLLYYSFLWSWWSVLPIQILSAISNRALWWAVGASVEDLATPRMERALSALFRGHF 499
           C   + +Y S+L + W+VLP+++L  +++ A+W A  + +     P +  +   + +G  
Sbjct: 519 CNTARYIYISYLENAWTVLPMEVLQGVTHAAIWAACISYLSAAVPPELRTSAQGILQGLH 578

Query: 500 YGSGCSLGSFVGGFVVMRFSLAVLYQ----ACCVALLL-----WLAL 537
            G G   G+ +GG +V  F  A  ++    AC V LLL     WLA+
Sbjct: 579 LGLGRGCGAMIGGVLVNYFGAAATFRGIGMACLVILLLFALIQWLAV 625


>gi|94721311 hippocampus abundant transcript-like 1 [Homo sapiens]
          Length = 506

 Score = 35.0 bits (79), Expect = 0.19
 Identities = 48/209 (22%), Positives = 88/209 (42%), Gaps = 24/209 (11%)

Query: 325 YGYSVVSTLALLVS--------IAFPIPICQQWEP-------SYKRVK---ALSIVGGDP 366
           YG S+V  +A +V+        +A P  + ++  P       S+K+     +L  VG D 
Sbjct: 193 YGDSLVVLVATVVALLDICFILVAVPESLPEKMRPVSWGAQISWKQADPFASLKKVGKDS 252

Query: 367 HLILLASTTVLVGAIVSTVQNFLFWHMKDH-GSGEL-VMGFSVALSLLGEILLHPFKATL 424
            ++L+  T  L     +   +  F +++   G G + +  F   + +L  +    F + L
Sbjct: 253 TVLLICITVFLSYLPEAGQYSSFFLYLRQVIGFGSVKIAAFIAMVGILSIVAQTAFLSIL 312

Query: 425 LRKLSRTGLVGLGLSCLAGQLLYYSF---LWSWWSVLPIQILSAISNRALWWAVGASVED 481
           +R L     V LGL     QL +Y F    W  W+   +  +S+I+  A+   V  + E 
Sbjct: 313 MRSLGNKNTVLLGLGFQMLQLAWYGFGSQAWMMWAAGTVAAMSSITFPAISALVSRNAES 372

Query: 482 LATPRMERALSALFRGHFYGSGCSLGSFV 510
                 +  ++ + RG   G G +L  F+
Sbjct: 373 DQQGVAQGIITGI-RGLCNGLGPALYGFI 400


>gi|39753965 hippocampus abundant transcript 1 [Homo sapiens]
          Length = 490

 Score = 34.3 bits (77), Expect = 0.33
 Identities = 40/161 (24%), Positives = 62/161 (38%), Gaps = 11/161 (6%)

Query: 364 GDPHLILLASTTVLVGAIVSTVQN---FLFWHMKDHGSGELVMGFSVALSLLGEILLHPF 420
           G   ++LL   TV +  +    Q    FL+       S E V  F   L +L  I     
Sbjct: 241 GQDSIVLLICITVFLSYLPEAGQYSSFFLYLRQIMKFSPESVAAFIAVLGILSIIAQTIV 300

Query: 421 KATLLRKLSRTGLVGLGLSCLAGQLLYYSF---LWSWWSVLPIQILSAISNRALWWAVGA 477
            + L+R +     + LGL     QL +Y F    W  W+   +  +S+I+    + AV A
Sbjct: 301 LSLLMRSIGNKNTILLGLGFQILQLAWYGFGSEPWMMWAAGAVAAMSSIT----FPAVSA 356

Query: 478 SVEDLATPRMERALSALFRGHFYGSGCSLGSFVGGFVVMRF 518
            V   A    +  +  +  G   G    LG  + GF+   F
Sbjct: 357 LVSRTADADQQGVVQGMITG-IRGLCNGLGPALYGFIFYIF 396


>gi|117190342 PHD finger protein 2 [Homo sapiens]
          Length = 1096

 Score = 32.0 bits (71), Expect = 1.6
 Identities = 26/77 (33%), Positives = 34/77 (44%), Gaps = 7/77 (9%)

Query: 112  SSGLTSTDALPGVTLPVNITSAQESASSHPAKRTAEVEMPGFRNPPGESDRETFRDLHVY 171
            S+G TST   P  T P + T A  S +S  A +  E   P    PP ES   +  D    
Sbjct: 973  SAGTTSTSTTPASTTPASTTPASTSTASSQASQ--EGSSP---EPPPESHSSSLADHEYT 1027

Query: 172  LAPSVEGART--TSQAL 186
             A +  GA+   TSQ +
Sbjct: 1028 AAGTFTGAQAGRTSQPM 1044


>gi|239750595 PREDICTED: similar to hCG2012058 [Homo sapiens]
          Length = 173

 Score = 30.8 bits (68), Expect = 3.6
 Identities = 27/88 (30%), Positives = 33/88 (37%), Gaps = 10/88 (11%)

Query: 45  APWVGTLMGTKHLIAAFWAPVC---AFLAK--SYRKRRALLIGSLLGSVGASLLMVLVPP 99
           +PW G   G++  + A WA  C    FL K    R R         G  GA  +  L   
Sbjct: 48  SPWRGWDPGSRGSVTAAWATACGDLTFLGKPMGQRSREIQAPSGRYGRTGAFAVEKLGVS 107

Query: 100 VDKNRVHFPCNGSSGLTSTDALPGVTLP 127
           V K R     NGS G +        TLP
Sbjct: 108 VGKER-----NGSRGSSGAPGNAAYTLP 130


>gi|74048554 cancer susceptibility candidate 5 isoform 2 [Homo
            sapiens]
          Length = 2316

 Score = 30.4 bits (67), Expect = 4.7
 Identities = 23/82 (28%), Positives = 34/82 (41%), Gaps = 9/82 (10%)

Query: 95   VLVPPVDKNRVHFPCNGSSG--------LTSTDALPGVTLPVNITSAQESASSHPAKRTA 146
            V+  P +++ V FP NG S         LT  +       PV +    E + S   K   
Sbjct: 988  VICTPTEES-VFFPGNGESDRLVANDSQLTPLEEWSNNRGPVEVADNMELSKSATCKNIK 1046

Query: 147  EVEMPGFRNPPGESDRETFRDL 168
            +V+ PGF N P  S  +  + L
Sbjct: 1047 DVQSPGFLNEPLSSKSQRRKSL 1068


>gi|74048514 cancer susceptibility candidate 5 isoform 1 [Homo
            sapiens]
          Length = 2342

 Score = 30.4 bits (67), Expect = 4.7
 Identities = 23/82 (28%), Positives = 34/82 (41%), Gaps = 9/82 (10%)

Query: 95   VLVPPVDKNRVHFPCNGSSG--------LTSTDALPGVTLPVNITSAQESASSHPAKRTA 146
            V+  P +++ V FP NG S         LT  +       PV +    E + S   K   
Sbjct: 1014 VICTPTEES-VFFPGNGESDRLVANDSQLTPLEEWSNNRGPVEVADNMELSKSATCKNIK 1072

Query: 147  EVEMPGFRNPPGESDRETFRDL 168
            +V+ PGF N P  S  +  + L
Sbjct: 1073 DVQSPGFLNEPLSSKSQRRKSL 1094


>gi|157412273 surfactant associated 3 [Homo sapiens]
          Length = 94

 Score = 30.4 bits (67), Expect = 4.7
 Identities = 23/73 (31%), Positives = 32/73 (43%), Gaps = 5/73 (6%)

Query: 142 AKRTAE-VEMPGFRNPPGESD----RETFRDLHVYLAPSVEGARTTSQALLHPVTSGLKD 196
           A+R  E +++ GF NP  ES     RE  + +   +A  V    T   ALLHP T     
Sbjct: 22  AQRLTEWLQLSGFENPVSESTTLCLREREKRIPTCVAVCVPSPGTVHTALLHPTTLSQSR 81

Query: 197 HPWEVTFEVVKTA 209
              E    ++ TA
Sbjct: 82  SSSEAKMLIIHTA 94


>gi|38488720 DiGeorge syndrome critical region gene 8 [Homo sapiens]
          Length = 773

 Score = 30.0 bits (66), Expect = 6.2
 Identities = 23/88 (26%), Positives = 39/88 (44%), Gaps = 5/88 (5%)

Query: 107 FPC-NGSSGLTSTDALPGVTLPVNITSAQESASSHPAKRTAEVEMPGFRNPPGESDRETF 165
           F C N S    ++  + GVT      S+++ A +  A+ T E+ +P F     E   +  
Sbjct: 533 FECENPSEPFGASVTIDGVTYGSGTASSKKLAKNKAARATLEILIPDFVKQTSEEKPKDS 592

Query: 166 RDLHVYLAPSVEGAR----TTSQALLHP 189
            +L  +   S+E +R    T+   LL P
Sbjct: 593 EELEYFNHISIEDSRVYELTSKAGLLSP 620


>gi|149274653 patched domain containing 2 [Homo sapiens]
          Length = 1392

 Score = 30.0 bits (66), Expect = 6.2
 Identities = 19/55 (34%), Positives = 27/55 (49%), Gaps = 7/55 (12%)

Query: 428 LSRTGLVGLGLSCLAGQLLYYSFLWSWWSVLPIQILSAISNRALWWAVGASVEDL 482
           LS  G+  +GLSCL    LY+        V  IQ L  ++  A +  VG  V+D+
Sbjct: 487 LSFFGIASIGLSCLVALFLYH-------VVFGIQYLGILNGVAAFVIVGIGVDDV 534


>gi|169172306 PREDICTED: hypothetical protein LOC441239 [Homo
           sapiens]
          Length = 505

 Score = 29.6 bits (65), Expect = 8.1
 Identities = 29/117 (24%), Positives = 42/117 (35%), Gaps = 17/117 (14%)

Query: 113 SGLTSTDALPGVTLPVNITSAQESASSHPAKRTAEVEMPGFRNPPGESDRETFRDLHVYL 172
           S L     L G   P+   ++ E A S   +   + + PGFR          + ++    
Sbjct: 241 SSLCEATELTGGRTPIETGTSDEGAPSSGWRVGQQQQQPGFRE---------WGEMRAPG 291

Query: 173 APSVEGARTTSQALLHPVTSGLKDHPWEVTFEVVKTALPLLTGGKGPGNPANLSGTK 229
           AP VE A+   Q         L  H  E       T L  + G  G G+PA    +K
Sbjct: 292 APQVEEAQVWMQV--------LDSHKGEEPVTHPTTPLKWVKGNPGAGHPAQKKRSK 340


>gi|169170482 PREDICTED: hypothetical protein LOC441239 [Homo
           sapiens]
          Length = 542

 Score = 29.6 bits (65), Expect = 8.1
 Identities = 29/117 (24%), Positives = 42/117 (35%), Gaps = 17/117 (14%)

Query: 113 SGLTSTDALPGVTLPVNITSAQESASSHPAKRTAEVEMPGFRNPPGESDRETFRDLHVYL 172
           S L     L G   P+   ++ E A S   +   + + PGFR          + ++    
Sbjct: 241 SSLCEATELTGGRTPIETGTSDEGAPSSGWRVGQQQQQPGFRE---------WGEMRAPG 291

Query: 173 APSVEGARTTSQALLHPVTSGLKDHPWEVTFEVVKTALPLLTGGKGPGNPANLSGTK 229
           AP VE A+   Q         L  H  E       T L  + G  G G+PA    +K
Sbjct: 292 APQVEEAQVWMQV--------LDSHKGEEPVTHPTTPLKWVKGNPGAGHPAQKKRSK 340


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.323    0.137    0.428 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 21,791,836
Number of Sequences: 37866
Number of extensions: 938271
Number of successful extensions: 2425
Number of sequences better than 10.0: 13
Number of HSP's better than 10.0 without gapping: 2
Number of HSP's successfully gapped in prelim test: 11
Number of HSP's that attempted gapping in prelim test: 2419
Number of HSP's gapped (non-prelim): 17
length of query: 586
length of database: 18,247,518
effective HSP length: 108
effective length of query: 478
effective length of database: 14,157,990
effective search space: 6767519220
effective search space used: 6767519220
T: 11
A: 40
X1: 16 ( 7.5 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (22.0 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.