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Search of human proteins with 4580420
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4580420 KIT ligand isoform a precursor [Homo sapiens]
(245 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4580420 KIT ligand isoform a precursor [Homo sapiens] 490 e-139
gi|4505175 KIT ligand isoform b precursor [Homo sapiens] 473 e-134
gi|75677574 cell cycle progression 1 isoform 2 [Homo sapiens] 33 0.29
gi|75677585 cell cycle progression 1 isoform 1 [Homo sapiens] 33 0.29
gi|61742786 leucine rich repeat and death domain containing prot... 31 1.1
gi|61742784 leucine rich repeat and death domain containing prot... 31 1.1
gi|61742782 leucine rich repeat and death domain containing prot... 31 1.1
gi|105990532 apolipoprotein B precursor [Homo sapiens] 29 4.3
gi|48255931 hepatoma-derived growth factor-related protein 2 iso... 29 4.3
gi|14249158 hepatoma-derived growth factor-related protein 2 iso... 29 4.3
gi|68348709 formin binding protein 1-like isoform 1 [Homo sapiens] 28 5.6
gi|41581463 formin binding protein 1-like isoform 2 [Homo sapiens] 28 5.6
gi|113420453 PREDICTED: similar to ubiquitin protein ligase E3 c... 28 7.3
gi|13994289 fibronectin type III and SPRY domain containing 1-li... 28 9.5
gi|52856424 olfactory receptor, family 5, subfamily H, member 1 ... 28 9.5
>gi|4580420 KIT ligand isoform a precursor [Homo sapiens]
Length = 245
Score = 490 bits (1262), Expect = e-139
Identities = 245/245 (100%), Positives = 245/245 (100%)
Query: 1 MKKTQTWILTCIYLQLLLFNPLVKTEGICRNRVTNNVKDVTKLVANLPKDYMITLKYVPG 60
MKKTQTWILTCIYLQLLLFNPLVKTEGICRNRVTNNVKDVTKLVANLPKDYMITLKYVPG
Sbjct: 1 MKKTQTWILTCIYLQLLLFNPLVKTEGICRNRVTNNVKDVTKLVANLPKDYMITLKYVPG 60
Query: 61 MDVLPSHCWISEMVVQLSDSLTDLLDKFSNISEGLSNYSIIDKLVNIVDDLVECVKENSS 120
MDVLPSHCWISEMVVQLSDSLTDLLDKFSNISEGLSNYSIIDKLVNIVDDLVECVKENSS
Sbjct: 61 MDVLPSHCWISEMVVQLSDSLTDLLDKFSNISEGLSNYSIIDKLVNIVDDLVECVKENSS 120
Query: 121 KDLKKSFKSPEPRLFTPEEFFRIFNRSIDAFKDFVVASETSDCVVSSTLSPEKGKAKNPP 180
KDLKKSFKSPEPRLFTPEEFFRIFNRSIDAFKDFVVASETSDCVVSSTLSPEKGKAKNPP
Sbjct: 121 KDLKKSFKSPEPRLFTPEEFFRIFNRSIDAFKDFVVASETSDCVVSSTLSPEKGKAKNPP 180
Query: 181 GDSSLHWAAMALPALFSLIIGFAFGALYWKKRQPSLTRAVENIQINEEDNEISMLQEKER 240
GDSSLHWAAMALPALFSLIIGFAFGALYWKKRQPSLTRAVENIQINEEDNEISMLQEKER
Sbjct: 181 GDSSLHWAAMALPALFSLIIGFAFGALYWKKRQPSLTRAVENIQINEEDNEISMLQEKER 240
Query: 241 EFQEV 245
EFQEV
Sbjct: 241 EFQEV 245
>gi|4505175 KIT ligand isoform b precursor [Homo sapiens]
Length = 273
Score = 473 bits (1216), Expect = e-134
Identities = 244/273 (89%), Positives = 244/273 (89%), Gaps = 28/273 (10%)
Query: 1 MKKTQTWILTCIYLQLLLFNPLVKTEGICRNRVTNNVKDVTKLVANLPKDYMITLKYVPG 60
MKKTQTWILTCIYLQLLLFNPLVKTEGICRNRVTNNVKDVTKLVANLPKDYMITLKYVPG
Sbjct: 1 MKKTQTWILTCIYLQLLLFNPLVKTEGICRNRVTNNVKDVTKLVANLPKDYMITLKYVPG 60
Query: 61 MDVLPSHCWISEMVVQLSDSLTDLLDKFSNISEGLSNYSIIDKLVNIVDDLVECVKENSS 120
MDVLPSHCWISEMVVQLSDSLTDLLDKFSNISEGLSNYSIIDKLVNIVDDLVECVKENSS
Sbjct: 61 MDVLPSHCWISEMVVQLSDSLTDLLDKFSNISEGLSNYSIIDKLVNIVDDLVECVKENSS 120
Query: 121 KDLKKSFKSPEPRLFTPEEFFRIFNRSIDAFKDFVVASETSDCVVSSTLSPEKG------ 174
KDLKKSFKSPEPRLFTPEEFFRIFNRSIDAFKDFVVASETSDCVVSSTLSPEK
Sbjct: 121 KDLKKSFKSPEPRLFTPEEFFRIFNRSIDAFKDFVVASETSDCVVSSTLSPEKDSRVSVT 180
Query: 175 ----------------------KAKNPPGDSSLHWAAMALPALFSLIIGFAFGALYWKKR 212
KAKNPPGDSSLHWAAMALPALFSLIIGFAFGALYWKKR
Sbjct: 181 KPFMLPPVAASSLRNDSSSSNRKAKNPPGDSSLHWAAMALPALFSLIIGFAFGALYWKKR 240
Query: 213 QPSLTRAVENIQINEEDNEISMLQEKEREFQEV 245
QPSLTRAVENIQINEEDNEISMLQEKEREFQEV
Sbjct: 241 QPSLTRAVENIQINEEDNEISMLQEKEREFQEV 273
>gi|75677574 cell cycle progression 1 isoform 2 [Homo sapiens]
Length = 757
Score = 32.7 bits (73), Expect = 0.29
Identities = 25/94 (26%), Positives = 43/94 (45%), Gaps = 2/94 (2%)
Query: 150 AFKDFVVASETSDCVVSST-LSPEKGKAKNPPGDSSLHWAAMALPALFSLIIGFAFGALY 208
A K V ASE+ D +V+ P K +K +AL S+ G +G +
Sbjct: 180 ARKKTVSASESEDRLVAEQETEPSKELSKRQFSSGLNKCVILALVIAISMGFGHFYGTIQ 239
Query: 209 WKKRQPSLTRAVENIQINEEDNEISMLQEKEREF 242
+KRQ L R + ++N+ + +S Q+++ F
Sbjct: 240 IQKRQ-QLVRKIHEDELNDMKDYLSQCQQEQESF 272
>gi|75677585 cell cycle progression 1 isoform 1 [Homo sapiens]
Length = 757
Score = 32.7 bits (73), Expect = 0.29
Identities = 25/94 (26%), Positives = 43/94 (45%), Gaps = 2/94 (2%)
Query: 150 AFKDFVVASETSDCVVSST-LSPEKGKAKNPPGDSSLHWAAMALPALFSLIIGFAFGALY 208
A K V ASE+ D +V+ P K +K +AL S+ G +G +
Sbjct: 180 ARKKTVSASESEDRLVAEQETEPSKELSKRQFSSGLNKCVILALVIAISMGFGHFYGTIQ 239
Query: 209 WKKRQPSLTRAVENIQINEEDNEISMLQEKEREF 242
+KRQ L R + ++N+ + +S Q+++ F
Sbjct: 240 IQKRQ-QLVRKIHEDELNDMKDYLSQCQQEQESF 272
>gi|61742786 leucine rich repeat and death domain containing protein
isoform 3 [Homo sapiens]
Length = 893
Score = 30.8 bits (68), Expect = 1.1
Identities = 20/62 (32%), Positives = 31/62 (50%), Gaps = 14/62 (22%)
Query: 111 LVECVKEN----SSKDLKKSFKSPEP----RLFTPEEFFRIFNRSIDAFKDFVVASETSD 162
L++C+ N + + L + ++ PEP +F EEFF F R ID V ++ D
Sbjct: 631 LLQCLPRNKVDATLRRLLERYRGPEPSDTVEMFEGEEFFAAFERGID------VDADRPD 684
Query: 163 CV 164
CV
Sbjct: 685 CV 686
>gi|61742784 leucine rich repeat and death domain containing protein
isoform 1 [Homo sapiens]
Length = 910
Score = 30.8 bits (68), Expect = 1.1
Identities = 20/62 (32%), Positives = 31/62 (50%), Gaps = 14/62 (22%)
Query: 111 LVECVKEN----SSKDLKKSFKSPEP----RLFTPEEFFRIFNRSIDAFKDFVVASETSD 162
L++C+ N + + L + ++ PEP +F EEFF F R ID V ++ D
Sbjct: 631 LLQCLPRNKVDATLRRLLERYRGPEPSDTVEMFEGEEFFAAFERGID------VDADRPD 684
Query: 163 CV 164
CV
Sbjct: 685 CV 686
>gi|61742782 leucine rich repeat and death domain containing protein
isoform 2 [Homo sapiens]
Length = 753
Score = 30.8 bits (68), Expect = 1.1
Identities = 20/62 (32%), Positives = 31/62 (50%), Gaps = 14/62 (22%)
Query: 111 LVECVKEN----SSKDLKKSFKSPEP----RLFTPEEFFRIFNRSIDAFKDFVVASETSD 162
L++C+ N + + L + ++ PEP +F EEFF F R ID V ++ D
Sbjct: 474 LLQCLPRNKVDATLRRLLERYRGPEPSDTVEMFEGEEFFAAFERGID------VDADRPD 527
Query: 163 CV 164
CV
Sbjct: 528 CV 529
>gi|105990532 apolipoprotein B precursor [Homo sapiens]
Length = 4563
Score = 28.9 bits (63), Expect = 4.3
Identities = 24/102 (23%), Positives = 44/102 (43%), Gaps = 12/102 (11%)
Query: 32 RVTNNVKDVTKLVANLPKDYMITLK---YVPGMDVLPSHCWISEMVVQLSDSLTDL---- 84
R+ + ++ V V NL D+ + K + + L + + + L D L +L
Sbjct: 2309 RINDVLEHVKHFVINLIGDFEVAEKINAFRAKVHELIERYEVDQQIQVLMDKLVELAHQY 2368
Query: 85 -----LDKFSNISEGLSNYSIIDKLVNIVDDLVECVKENSSK 121
+ K SN+ + + +KLV +DD V+ + E S K
Sbjct: 2369 KLKETIQKLSNVLQQVKIKDYFEKLVGFIDDAVKKLNELSFK 2410
>gi|48255931 hepatoma-derived growth factor-related protein 2
isoform 1 [Homo sapiens]
Length = 671
Score = 28.9 bits (63), Expect = 4.3
Identities = 12/36 (33%), Positives = 23/36 (63%)
Query: 209 WKKRQPSLTRAVENIQINEEDNEISMLQEKEREFQE 244
WK+R + R +E + E++ E+ L+E+E+E +E
Sbjct: 316 WKRRDEARRRELEARRRREQEEELRRLREQEKEEKE 351
>gi|14249158 hepatoma-derived growth factor-related protein 2
isoform 2 [Homo sapiens]
Length = 670
Score = 28.9 bits (63), Expect = 4.3
Identities = 12/36 (33%), Positives = 23/36 (63%)
Query: 209 WKKRQPSLTRAVENIQINEEDNEISMLQEKEREFQE 244
WK+R + R +E + E++ E+ L+E+E+E +E
Sbjct: 316 WKRRDEARRRELEARRRREQEEELRRLREQEKEEKE 351
>gi|68348709 formin binding protein 1-like isoform 1 [Homo sapiens]
Length = 551
Score = 28.5 bits (62), Expect = 5.6
Identities = 25/89 (28%), Positives = 42/89 (47%), Gaps = 12/89 (13%)
Query: 82 TDLLDKFSNISEGLS-NYSIIDKLVNIVDDLVECVKENSSKDL---------KKSFKSPE 131
T+L D+F ++ + +++ V + +E +++N +K L K+S K E
Sbjct: 5 TELWDQFDSLDKHTQWGIDFLERYAKFVKERIE-IEQNYAKQLRNLVKKYCPKRSSKDEE 63
Query: 132 PRLFTPEEFFRIFNRSID-AFKDFVVASE 159
PR + FF I N D A + VVA E
Sbjct: 64 PRFTSCVAFFNILNELNDYAGQREVVAEE 92
>gi|41581463 formin binding protein 1-like isoform 2 [Homo sapiens]
Length = 547
Score = 28.5 bits (62), Expect = 5.6
Identities = 25/89 (28%), Positives = 42/89 (47%), Gaps = 12/89 (13%)
Query: 82 TDLLDKFSNISEGLS-NYSIIDKLVNIVDDLVECVKENSSKDL---------KKSFKSPE 131
T+L D+F ++ + +++ V + +E +++N +K L K+S K E
Sbjct: 5 TELWDQFDSLDKHTQWGIDFLERYAKFVKERIE-IEQNYAKQLRNLVKKYCPKRSSKDEE 63
Query: 132 PRLFTPEEFFRIFNRSID-AFKDFVVASE 159
PR + FF I N D A + VVA E
Sbjct: 64 PRFTSCVAFFNILNELNDYAGQREVVAEE 92
>gi|113420453 PREDICTED: similar to ubiquitin protein ligase E3
component n-recognin 5 isoform 1 [Homo sapiens]
Length = 2796
Score = 28.1 bits (61), Expect = 7.3
Identities = 50/241 (20%), Positives = 92/241 (38%), Gaps = 31/241 (12%)
Query: 9 LTCIYLQLLLFNPLVKTEGICRNRVTNNVKDVTKLVANLPKDYMITLKYVPGMDVLPSHC 68
LT + LL N + T +N+V V + VA+ + T + G ++ HC
Sbjct: 418 LTNEKIVLLSANSIRATVATEKNKVATWVDETLSSVASKLEHTAQTYSELQGERIVSLHC 477
Query: 69 WISEMVVQLSDSL-----------TDLLDKFSNISEGLSNYSIIDKLVNIVDDLVECVKE 117
QL +SL +L+K ++ + + I + NI C++
Sbjct: 478 CALYTCAQLENSLYWWGVVPFSQRKKMLEKARAKNKKPKSSAGISSMPNITVGTQVCLRN 537
Query: 118 N---SSKDLKKSFKSPEPR-------LFTPEEFFRIFNRSIDAFKDFVVASETSDCVVSS 167
N + + S + P+ ++ + R RS ++ K+ AS+T++ S
Sbjct: 538 NPLYHAGAVAFSISAGIPKVGVLMESVWNMNDSCRFQLRSPESLKNMEKASKTTEAKPES 597
Query: 168 TLSPEKGKAKNPPGDSSLHWAAMALPALFSLIIGFAFGALYWKKRQPSLTRAVENIQINE 227
P K + PP +S A ++ + S+ KR+ S E ++NE
Sbjct: 598 KQEPVKTEMGPPPSPASTCSDASSIASSASMPY----------KRRRSTPAPKEEEKVNE 647
Query: 228 E 228
E
Sbjct: 648 E 648
>gi|13994289 fibronectin type III and SPRY domain containing 1-like
isoform 2 [Homo sapiens]
Length = 145
Score = 27.7 bits (60), Expect = 9.5
Identities = 22/88 (25%), Positives = 38/88 (43%), Gaps = 11/88 (12%)
Query: 70 ISEMVVQLSDSLTDLLDKFSNISEGL-----SNYSIIDKLVNIVDDLVECVKE---NSSK 121
I + L +L + + SNI L S YSI+D+ + + ++ C+K+ S+
Sbjct: 22 IQNFIDTLHHTLKGVQENSSNILSELDEEFDSLYSILDE---VKESMINCIKQEQARKSQ 78
Query: 122 DLKKSFKSPEPRLFTPEEFFRIFNRSID 149
+L+ L EE RS+D
Sbjct: 79 ELQSQISQCNNALENSEELLEFATRSLD 106
>gi|52856424 olfactory receptor, family 5, subfamily H, member 1
[Homo sapiens]
Length = 313
Score = 27.7 bits (60), Expect = 9.5
Identities = 30/126 (23%), Positives = 57/126 (45%), Gaps = 5/126 (3%)
Query: 18 LFNPLVKTEGIC-RNRVTNNVKDVTKLVANLPKDYMITLKYVPGMDVLPSHC-WISEMVV 75
L P + T G+C R + + V + L A + + ++ L + V +C I +
Sbjct: 130 LLYPAIMTNGLCIRLLILSYVGGI--LHALIHEGFLFRLTFCNSNIVHHIYCDTIPLSKI 187
Query: 76 QLSDSLTDLLDKFSNISEGLSNYSIIDKLVNIVDDLVECVKENSSKDLKKSFKSPEPRLF 135
+DS + L F S + +SI+ LV+ L +K+ S K ++K+F + LF
Sbjct: 188 SCTDSSINFLMVFI-FSGSIQVFSIVTILVSYTFVLFAILKKKSDKGVRKAFSTCGAHLF 246
Query: 136 TPEEFF 141
+ ++
Sbjct: 247 SVSLYY 252
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.318 0.134 0.391
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 9,301,951
Number of Sequences: 37866
Number of extensions: 383241
Number of successful extensions: 1149
Number of sequences better than 10.0: 15
Number of HSP's better than 10.0 without gapping: 4
Number of HSP's successfully gapped in prelim test: 11
Number of HSP's that attempted gapping in prelim test: 1140
Number of HSP's gapped (non-prelim): 15
length of query: 245
length of database: 18,247,518
effective HSP length: 100
effective length of query: 145
effective length of database: 14,460,918
effective search space: 2096833110
effective search space used: 2096833110
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 60 (27.7 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.