Guide to the Human Genome
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Search of human proteins with 13236514

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|13236514 chromosome 6 open reading frame 106 isoform a [Homo
sapiens]
         (298 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|13236514 chromosome 6 open reading frame 106 isoform a [Homo ...   621   e-178
gi|46094086 chromosome 6 open reading frame 106 isoform b [Homo ...   268   6e-72
gi|14110378 neighbor of BRCA1 gene 1 [Homo sapiens]                    55   1e-07
gi|14110375 neighbor of BRCA1 gene 1 [Homo sapiens]                    55   1e-07
gi|14110381 neighbor of BRCA1 gene 1 [Homo sapiens]                    55   1e-07
gi|16753207 ubiquilin 2 [Homo sapiens]                                 30   2.0  
gi|154813197 talpid3 protein [Homo sapiens]                            30   2.0  
gi|239049540 FCH domain only 1 isoform c [Homo sapiens]                30   3.4  
gi|239049457 FCH domain only 1 isoform b [Homo sapiens]                30   3.4  
gi|29789054 FCH domain only 1 isoform b [Homo sapiens]                 30   3.4  
gi|239049440 FCH domain only 1 isoform a [Homo sapiens]                30   3.4  
gi|55750053 atrophin-1 [Homo sapiens]                                  29   4.4  
gi|55750041 atrophin-1 [Homo sapiens]                                  29   4.4  
gi|148236531 hypothetical protein LOC339779 [Homo sapiens]             28   7.5  
gi|76150625 nucleolar protein 1, 120kDa [Homo sapiens]                 28   9.8  
gi|76150623 nucleolar protein 1, 120kDa [Homo sapiens]                 28   9.8  

>gi|13236514 chromosome 6 open reading frame 106 isoform a [Homo
           sapiens]
          Length = 298

 Score =  621 bits (1601), Expect = e-178
 Identities = 298/298 (100%), Positives = 298/298 (100%)

Query: 1   MEGMDVDLDPELMQKFSCLGTTDKDVLISEFQRLLGFQLNPAGCAFFLDMTNWNLQAAIG 60
           MEGMDVDLDPELMQKFSCLGTTDKDVLISEFQRLLGFQLNPAGCAFFLDMTNWNLQAAIG
Sbjct: 1   MEGMDVDLDPELMQKFSCLGTTDKDVLISEFQRLLGFQLNPAGCAFFLDMTNWNLQAAIG 60

Query: 61  AYYDFESPNISVPSMSFVEDVTIGEGESIPPDTQFVKTWRIQNSGAEAWPPGVCLKYVGG 120
           AYYDFESPNISVPSMSFVEDVTIGEGESIPPDTQFVKTWRIQNSGAEAWPPGVCLKYVGG
Sbjct: 61  AYYDFESPNISVPSMSFVEDVTIGEGESIPPDTQFVKTWRIQNSGAEAWPPGVCLKYVGG 120

Query: 121 DQFGHVNMVMVRSLEPQEIADVSVQMCSPSRAGMYQGQWRMCTATGLYYGDVIWVILSVE 180
           DQFGHVNMVMVRSLEPQEIADVSVQMCSPSRAGMYQGQWRMCTATGLYYGDVIWVILSVE
Sbjct: 121 DQFGHVNMVMVRSLEPQEIADVSVQMCSPSRAGMYQGQWRMCTATGLYYGDVIWVILSVE 180

Query: 181 VGGLLGVTQQLSSFETEFNTQPHRKVEGNFNPFASPQKNRQSDENNLKDPGGSEFDSISK 240
           VGGLLGVTQQLSSFETEFNTQPHRKVEGNFNPFASPQKNRQSDENNLKDPGGSEFDSISK
Sbjct: 181 VGGLLGVTQQLSSFETEFNTQPHRKVEGNFNPFASPQKNRQSDENNLKDPGGSEFDSISK 240

Query: 241 NTWAPAPDTWAPAPDQTEQDQNRLSQNSVNLSPSSHANNLSVVTYSKGLHGPYPFGQS 298
           NTWAPAPDTWAPAPDQTEQDQNRLSQNSVNLSPSSHANNLSVVTYSKGLHGPYPFGQS
Sbjct: 241 NTWAPAPDTWAPAPDQTEQDQNRLSQNSVNLSPSSHANNLSVVTYSKGLHGPYPFGQS 298


>gi|46094086 chromosome 6 open reading frame 106 isoform b [Homo
           sapiens]
          Length = 232

 Score =  268 bits (684), Expect = 6e-72
 Identities = 128/128 (100%), Positives = 128/128 (100%)

Query: 171 DVIWVILSVEVGGLLGVTQQLSSFETEFNTQPHRKVEGNFNPFASPQKNRQSDENNLKDP 230
           DVIWVILSVEVGGLLGVTQQLSSFETEFNTQPHRKVEGNFNPFASPQKNRQSDENNLKDP
Sbjct: 105 DVIWVILSVEVGGLLGVTQQLSSFETEFNTQPHRKVEGNFNPFASPQKNRQSDENNLKDP 164

Query: 231 GGSEFDSISKNTWAPAPDTWAPAPDQTEQDQNRLSQNSVNLSPSSHANNLSVVTYSKGLH 290
           GGSEFDSISKNTWAPAPDTWAPAPDQTEQDQNRLSQNSVNLSPSSHANNLSVVTYSKGLH
Sbjct: 165 GGSEFDSISKNTWAPAPDTWAPAPDQTEQDQNRLSQNSVNLSPSSHANNLSVVTYSKGLH 224

Query: 291 GPYPFGQS 298
           GPYPFGQS
Sbjct: 225 GPYPFGQS 232



 Score =  216 bits (551), Expect = 1e-56
 Identities = 104/104 (100%), Positives = 104/104 (100%)

Query: 1   MEGMDVDLDPELMQKFSCLGTTDKDVLISEFQRLLGFQLNPAGCAFFLDMTNWNLQAAIG 60
           MEGMDVDLDPELMQKFSCLGTTDKDVLISEFQRLLGFQLNPAGCAFFLDMTNWNLQAAIG
Sbjct: 1   MEGMDVDLDPELMQKFSCLGTTDKDVLISEFQRLLGFQLNPAGCAFFLDMTNWNLQAAIG 60

Query: 61  AYYDFESPNISVPSMSFVEDVTIGEGESIPPDTQFVKTWRIQNS 104
           AYYDFESPNISVPSMSFVEDVTIGEGESIPPDTQFVKTWRIQNS
Sbjct: 61  AYYDFESPNISVPSMSFVEDVTIGEGESIPPDTQFVKTWRIQNS 104


>gi|14110378 neighbor of BRCA1 gene 1 [Homo sapiens]
          Length = 966

 Score = 54.7 bits (130), Expect = 1e-07
 Identities = 31/110 (28%), Positives = 57/110 (51%), Gaps = 5/110 (4%)

Query: 74  SMSFVEDVTIGEGESIPPDTQFVKTWRIQNSGAEAWPPGVCLKYVGGD---QFGHVNMVM 130
           S +FV++  + +G  + P T+F+K WR++N+G   W     LK++ G+          V+
Sbjct: 372 SAAFVDE-NLPDGTHLQPGTKFIKHWRMKNTGNVKWSADTKLKFMWGNLTLASTEKKDVL 430

Query: 131 VRSLEPQEIADVSVQMCSPSRAGMYQGQWRMCTATGLYYGDVIWVILSVE 180
           V  L+   +  VSV+  +P+  G Y   WR+ +  G  +G  +W  + V+
Sbjct: 431 VPCLKAGHVGVVSVEFIAPALEGTYTSHWRL-SHKGQQFGPRVWCSIIVD 479


>gi|14110375 neighbor of BRCA1 gene 1 [Homo sapiens]
          Length = 966

 Score = 54.7 bits (130), Expect = 1e-07
 Identities = 31/110 (28%), Positives = 57/110 (51%), Gaps = 5/110 (4%)

Query: 74  SMSFVEDVTIGEGESIPPDTQFVKTWRIQNSGAEAWPPGVCLKYVGGD---QFGHVNMVM 130
           S +FV++  + +G  + P T+F+K WR++N+G   W     LK++ G+          V+
Sbjct: 372 SAAFVDE-NLPDGTHLQPGTKFIKHWRMKNTGNVKWSADTKLKFMWGNLTLASTEKKDVL 430

Query: 131 VRSLEPQEIADVSVQMCSPSRAGMYQGQWRMCTATGLYYGDVIWVILSVE 180
           V  L+   +  VSV+  +P+  G Y   WR+ +  G  +G  +W  + V+
Sbjct: 431 VPCLKAGHVGVVSVEFIAPALEGTYTSHWRL-SHKGQQFGPRVWCSIIVD 479


>gi|14110381 neighbor of BRCA1 gene 1 [Homo sapiens]
          Length = 966

 Score = 54.7 bits (130), Expect = 1e-07
 Identities = 31/110 (28%), Positives = 57/110 (51%), Gaps = 5/110 (4%)

Query: 74  SMSFVEDVTIGEGESIPPDTQFVKTWRIQNSGAEAWPPGVCLKYVGGD---QFGHVNMVM 130
           S +FV++  + +G  + P T+F+K WR++N+G   W     LK++ G+          V+
Sbjct: 372 SAAFVDE-NLPDGTHLQPGTKFIKHWRMKNTGNVKWSADTKLKFMWGNLTLASTEKKDVL 430

Query: 131 VRSLEPQEIADVSVQMCSPSRAGMYQGQWRMCTATGLYYGDVIWVILSVE 180
           V  L+   +  VSV+  +P+  G Y   WR+ +  G  +G  +W  + V+
Sbjct: 431 VPCLKAGHVGVVSVEFIAPALEGTYTSHWRL-SHKGQQFGPRVWCSIIVD 479


>gi|16753207 ubiquilin 2 [Homo sapiens]
          Length = 624

 Score = 30.4 bits (67), Expect = 2.0
 Identities = 23/75 (30%), Positives = 30/75 (40%), Gaps = 5/75 (6%)

Query: 211 NPFASPQKNRQSDENNLKDPGGSEFDSISKNTWAPAPDTWAPAPDQTEQDQNRLSQNSVN 270
           NPFAS   +  S E     P  +E      N WAP P T + A   T       S NS  
Sbjct: 290 NPFASVGSSSSSGEGT--QPSRTENRDPLPNPWAPPPATQSSATTSTTTSTGSGSGNS-- 345

Query: 271 LSPSSHANNLSVVTY 285
            S ++  N ++   Y
Sbjct: 346 -SSNATGNTVAAANY 359


>gi|154813197 talpid3 protein [Homo sapiens]
          Length = 1472

 Score = 30.4 bits (67), Expect = 2.0
 Identities = 23/91 (25%), Positives = 40/91 (43%), Gaps = 7/91 (7%)

Query: 197 EFNTQPHRKVEGNFNPFASPQKNRQSDENNLKDPGGSEFDSISKNTWAPAPDTWAPAP-- 254
           +++ +P     G+ NP  S      S +  LK+   + FD        PAP  +AP P  
Sbjct: 295 KYSVKPEHPNLGSCNP--SLYNTFASKQAPLKEVEDTSFDKQKSPLETPAPRRFAPVPVS 352

Query: 255 --DQTEQDQNRLSQNSVNLSPSSHANNLSVV 283
             D+  + +N L +   N+  S H  N+ ++
Sbjct: 353 RDDELSKRENLLEEKE-NMEVSCHRGNVRLL 382


>gi|239049540 FCH domain only 1 isoform c [Homo sapiens]
          Length = 839

 Score = 29.6 bits (65), Expect = 3.4
 Identities = 15/41 (36%), Positives = 20/41 (48%), Gaps = 3/41 (7%)

Query: 214 ASPQKNRQSDENNLKDPGGSEFDSISKNTWAPAPDTWAPAP 254
           +SP     S   N++D G    DS S     P+PD+W P P
Sbjct: 409 SSPSPFSSSSPENVEDSG---LDSPSHAAPGPSPDSWVPRP 446


>gi|239049457 FCH domain only 1 isoform b [Homo sapiens]
          Length = 889

 Score = 29.6 bits (65), Expect = 3.4
 Identities = 15/41 (36%), Positives = 20/41 (48%), Gaps = 3/41 (7%)

Query: 214 ASPQKNRQSDENNLKDPGGSEFDSISKNTWAPAPDTWAPAP 254
           +SP     S   N++D G    DS S     P+PD+W P P
Sbjct: 459 SSPSPFSSSSPENVEDSG---LDSPSHAAPGPSPDSWVPRP 496


>gi|29789054 FCH domain only 1 isoform b [Homo sapiens]
          Length = 889

 Score = 29.6 bits (65), Expect = 3.4
 Identities = 15/41 (36%), Positives = 20/41 (48%), Gaps = 3/41 (7%)

Query: 214 ASPQKNRQSDENNLKDPGGSEFDSISKNTWAPAPDTWAPAP 254
           +SP     S   N++D G    DS S     P+PD+W P P
Sbjct: 459 SSPSPFSSSSPENVEDSG---LDSPSHAAPGPSPDSWVPRP 496


>gi|239049440 FCH domain only 1 isoform a [Homo sapiens]
          Length = 891

 Score = 29.6 bits (65), Expect = 3.4
 Identities = 15/41 (36%), Positives = 20/41 (48%), Gaps = 3/41 (7%)

Query: 214 ASPQKNRQSDENNLKDPGGSEFDSISKNTWAPAPDTWAPAP 254
           +SP     S   N++D G    DS S     P+PD+W P P
Sbjct: 459 SSPSPFSSSSPENVEDSG---LDSPSHAAPGPSPDSWVPRP 496


>gi|55750053 atrophin-1 [Homo sapiens]
          Length = 1190

 Score = 29.3 bits (64), Expect = 4.4
 Identities = 18/78 (23%), Positives = 35/78 (44%), Gaps = 1/78 (1%)

Query: 186 GVTQQLSSFETEFNTQPHR-KVEGNFNPFASPQKNRQSDENNLKDPGGSEFDSISKNTWA 244
           G ++++S  E+E    P + K E       SP      D  +L D G S+   I ++  +
Sbjct: 71  GRSEEISESESEETNAPKKTKTEQELPRPQSPSDLDSLDGRSLNDDGSSDPRDIDQDNRS 130

Query: 245 PAPDTWAPAPDQTEQDQN 262
            +P  ++P   + + D +
Sbjct: 131 TSPSIYSPGSVENDSDSS 148


>gi|55750041 atrophin-1 [Homo sapiens]
          Length = 1190

 Score = 29.3 bits (64), Expect = 4.4
 Identities = 18/78 (23%), Positives = 35/78 (44%), Gaps = 1/78 (1%)

Query: 186 GVTQQLSSFETEFNTQPHR-KVEGNFNPFASPQKNRQSDENNLKDPGGSEFDSISKNTWA 244
           G ++++S  E+E    P + K E       SP      D  +L D G S+   I ++  +
Sbjct: 71  GRSEEISESESEETNAPKKTKTEQELPRPQSPSDLDSLDGRSLNDDGSSDPRDIDQDNRS 130

Query: 245 PAPDTWAPAPDQTEQDQN 262
            +P  ++P   + + D +
Sbjct: 131 TSPSIYSPGSVENDSDSS 148


>gi|148236531 hypothetical protein LOC339779 [Homo sapiens]
          Length = 412

 Score = 28.5 bits (62), Expect = 7.5
 Identities = 24/77 (31%), Positives = 34/77 (44%), Gaps = 2/77 (2%)

Query: 202 PHRKVEGNFNPFASPQKNRQSDENNLKDPGGSEFDSISKNT-WAPAPDTWAPAPDQTEQD 260
           PH+ +  +  PF+S Q  R S         G +F S   N+ +AP P + +     T   
Sbjct: 40  PHQGLPPSQPPFSSTQSRRPSSPPPASPSPGFQFGSCDSNSDFAPHPYSPSLPSSPTFFH 99

Query: 261 QNRLSQNSVNL-SPSSH 276
           QN LS       SPS+H
Sbjct: 100 QNYLSLPRPRASSPSNH 116


>gi|76150625 nucleolar protein 1, 120kDa [Homo sapiens]
          Length = 808

 Score = 28.1 bits (61), Expect = 9.8
 Identities = 35/133 (26%), Positives = 54/133 (40%), Gaps = 10/133 (7%)

Query: 83  IGEGESIPPDTQFVKTWRIQNSGAEAWPPGVCLKYVGGDQF--GHVNMVMVRSLEPQEIA 140
           I  G ++ P  ++ KT  +    +   P G   +Y+ G     G  +M+ V +L PQE  
Sbjct: 325 INRGVNLDPLGKWSKTGLVVYDSSV--PIGATPEYLAGHYMLQGASSMLPVMALAPQEHE 382

Query: 141 DVSVQMCSPSRAGMYQGQWRMCTATGLYYGDVIWVILSVEVGGL--LGVTQQLSSFETEF 198
            +    C+P     Y  Q    T   +   D     L   VG L  LGVT  + S    +
Sbjct: 383 RILDMCCAPGGKTSYMAQLMKNTGV-ILANDANAERLKSVVGNLHRLGVTNTIIS---HY 438

Query: 199 NTQPHRKVEGNFN 211
           + +   KV G F+
Sbjct: 439 DGRQFPKVVGGFD 451


>gi|76150623 nucleolar protein 1, 120kDa [Homo sapiens]
          Length = 808

 Score = 28.1 bits (61), Expect = 9.8
 Identities = 35/133 (26%), Positives = 54/133 (40%), Gaps = 10/133 (7%)

Query: 83  IGEGESIPPDTQFVKTWRIQNSGAEAWPPGVCLKYVGGDQF--GHVNMVMVRSLEPQEIA 140
           I  G ++ P  ++ KT  +    +   P G   +Y+ G     G  +M+ V +L PQE  
Sbjct: 325 INRGVNLDPLGKWSKTGLVVYDSSV--PIGATPEYLAGHYMLQGASSMLPVMALAPQEHE 382

Query: 141 DVSVQMCSPSRAGMYQGQWRMCTATGLYYGDVIWVILSVEVGGL--LGVTQQLSSFETEF 198
            +    C+P     Y  Q    T   +   D     L   VG L  LGVT  + S    +
Sbjct: 383 RILDMCCAPGGKTSYMAQLMKNTGV-ILANDANAERLKSVVGNLHRLGVTNTIIS---HY 438

Query: 199 NTQPHRKVEGNFN 211
           + +   KV G F+
Sbjct: 439 DGRQFPKVVGGFD 451


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.315    0.133    0.410 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 13,108,773
Number of Sequences: 37866
Number of extensions: 630818
Number of successful extensions: 1470
Number of sequences better than 10.0: 16
Number of HSP's better than 10.0 without gapping: 5
Number of HSP's successfully gapped in prelim test: 11
Number of HSP's that attempted gapping in prelim test: 1452
Number of HSP's gapped (non-prelim): 20
length of query: 298
length of database: 18,247,518
effective HSP length: 102
effective length of query: 196
effective length of database: 14,385,186
effective search space: 2819496456
effective search space used: 2819496456
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 61 (28.1 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
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