Guide to the Human Genome
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Search of human proteins with 13186236

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|13186236 fibroblast growth factor receptor 1 isoform 4
precursor [Homo sapiens]
         (731 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|13186236 fibroblast growth factor receptor 1 isoform 4 precur...  1502   0.0  
gi|13186234 fibroblast growth factor receptor 1 isoform 3 precur...  1497   0.0  
gi|13186251 fibroblast growth factor receptor 1 isoform 2 precur...  1436   0.0  
gi|105990522 fibroblast growth factor receptor 1 isoform 1 precu...  1431   0.0  
gi|13186249 fibroblast growth factor receptor 1 isoform 9 precur...  1331   0.0  
gi|221316639 fibroblast growth factor receptor 2 isoform 1 precu...  1125   0.0  
gi|222144237 fibroblast growth factor receptor 2 isoform 6 precu...  1117   0.0  
gi|222144241 fibroblast growth factor receptor 2 isoform 8 precu...  1109   0.0  
gi|221316638 fibroblast growth factor receptor 2 isoform 2 precu...  1078   0.0  
gi|222144235 fibroblast growth factor receptor 2 isoform 5 precu...  1068   0.0  
gi|222144244 fibroblast growth factor receptor 2 isoform 9 precu...  1016   0.0  
gi|222144231 fibroblast growth factor receptor 2 isoform 3 precu...  1002   0.0  
gi|4503711 fibroblast growth factor receptor 3 isoform 1 precurs...   986   0.0  
gi|254028242 fibroblast growth factor receptor 3 isoform 3 precu...   926   0.0  
gi|47524175 fibroblast growth factor receptor 4 isoform 1 precur...   868   0.0  
gi|47524173 fibroblast growth factor receptor 4 isoform 1 precur...   868   0.0  
gi|47524177 fibroblast growth factor receptor 4 isoform 2 precur...   841   0.0  
gi|222144233 fibroblast growth factor receptor 2 isoform 4 precu...   788   0.0  
gi|222144239 fibroblast growth factor receptor 2 isoform 7 precu...   709   0.0  
gi|13112048 fibroblast growth factor receptor 3 isoform 2 precur...   634   0.0  
gi|13186241 fibroblast growth factor receptor 1 isoform 6 precur...   471   e-132
gi|13186238 fibroblast growth factor receptor 1 isoform 5 precur...   466   e-131
gi|11321597 kinase insert domain receptor precursor [Homo sapiens]    334   2e-91
gi|10862701 ret proto-oncogene isoform c [Homo sapiens]               328   1e-89
gi|10862703 ret proto-oncogene isoform a [Homo sapiens]               328   1e-89
gi|156104876 fms-related tyrosine kinase 1 isoform 1 precursor [...   321   2e-87
gi|148005039 v-kit Hardy-Zuckerman 4 feline sarcoma viral oncoge...   269   6e-72
gi|4557695 v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene...   268   2e-71
gi|4885631 tyrosine kinase with immunoglobulin-like and EGF-like...   250   4e-66
gi|88758596 TEK tyrosine kinase, endothelial precursor [Homo sap...   244   3e-64

>gi|13186236 fibroblast growth factor receptor 1 isoform 4 precursor
           [Homo sapiens]
          Length = 731

 Score = 1502 bits (3888), Expect = 0.0
 Identities = 731/731 (100%), Positives = 731/731 (100%)

Query: 1   MWSWKCLLFWAVLVTATLCTARPSPTLPEQDALPSSEDDDDDDDSSSEEKETDNTKPNPV 60
           MWSWKCLLFWAVLVTATLCTARPSPTLPEQDALPSSEDDDDDDDSSSEEKETDNTKPNPV
Sbjct: 1   MWSWKCLLFWAVLVTATLCTARPSPTLPEQDALPSSEDDDDDDDSSSEEKETDNTKPNPV 60

Query: 61  APYWTSPEKMEKKLHAVPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPDHRIGGYKVRYA 120
           APYWTSPEKMEKKLHAVPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPDHRIGGYKVRYA
Sbjct: 61  APYWTSPEKMEKKLHAVPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPDHRIGGYKVRYA 120

Query: 121 TWSIIMDSVVPSDKGNYTCIVENEYGSINHTYQLDVVERSPHRPILQAGLPANKTVALGS 180
           TWSIIMDSVVPSDKGNYTCIVENEYGSINHTYQLDVVERSPHRPILQAGLPANKTVALGS
Sbjct: 121 TWSIIMDSVVPSDKGNYTCIVENEYGSINHTYQLDVVERSPHRPILQAGLPANKTVALGS 180

Query: 181 NVEFMCKVYSDPQPHIQWLKHIEVNGSKIGPDNLPYVQILKTAGVNTTDKEMEVLHLRNV 240
           NVEFMCKVYSDPQPHIQWLKHIEVNGSKIGPDNLPYVQILKTAGVNTTDKEMEVLHLRNV
Sbjct: 181 NVEFMCKVYSDPQPHIQWLKHIEVNGSKIGPDNLPYVQILKTAGVNTTDKEMEVLHLRNV 240

Query: 241 SFEDAGEYTCLAGNSIGLSHHSAWLTVLEALEERPAVMTSPLYLEIIIYCTGAFLISCMV 300
           SFEDAGEYTCLAGNSIGLSHHSAWLTVLEALEERPAVMTSPLYLEIIIYCTGAFLISCMV
Sbjct: 241 SFEDAGEYTCLAGNSIGLSHHSAWLTVLEALEERPAVMTSPLYLEIIIYCTGAFLISCMV 300

Query: 301 GSVIVYKMKSGTKKSDFHSQMAVHKLAKSIPLRRQVTVSADSSASMNSGVLLVRPSRLSS 360
           GSVIVYKMKSGTKKSDFHSQMAVHKLAKSIPLRRQVTVSADSSASMNSGVLLVRPSRLSS
Sbjct: 301 GSVIVYKMKSGTKKSDFHSQMAVHKLAKSIPLRRQVTVSADSSASMNSGVLLVRPSRLSS 360

Query: 361 SGTPMLAGVSEYELPEDPRWELPRDRLVLGKPLGEGCFGQVVLAEAIGLDKDKPNRVTKV 420
           SGTPMLAGVSEYELPEDPRWELPRDRLVLGKPLGEGCFGQVVLAEAIGLDKDKPNRVTKV
Sbjct: 361 SGTPMLAGVSEYELPEDPRWELPRDRLVLGKPLGEGCFGQVVLAEAIGLDKDKPNRVTKV 420

Query: 421 AVKMLKSDATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLRE 480
           AVKMLKSDATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLRE
Sbjct: 421 AVKMLKSDATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLRE 480

Query: 481 YLQARRPPGLEYCYNPSHNPEEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLV 540
           YLQARRPPGLEYCYNPSHNPEEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLV
Sbjct: 481 YLQARRPPGLEYCYNPSHNPEEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLV 540

Query: 541 TEDNVMKIADFGLARDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLW 600
           TEDNVMKIADFGLARDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLW
Sbjct: 541 TEDNVMKIADFGLARDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLW 600

Query: 601 EIFTLGGSPYPGVPVEELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQLV 660
           EIFTLGGSPYPGVPVEELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQLV
Sbjct: 601 EIFTLGGSPYPGVPVEELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQLV 660

Query: 661 EDLDRIVALTSNQEYLDLSMPLDQYSPSFPDTRSSTCSSGEDSVFSHEPLPEEPCLPRHP 720
           EDLDRIVALTSNQEYLDLSMPLDQYSPSFPDTRSSTCSSGEDSVFSHEPLPEEPCLPRHP
Sbjct: 661 EDLDRIVALTSNQEYLDLSMPLDQYSPSFPDTRSSTCSSGEDSVFSHEPLPEEPCLPRHP 720

Query: 721 AQLANGGLKRR 731
           AQLANGGLKRR
Sbjct: 721 AQLANGGLKRR 731


>gi|13186234 fibroblast growth factor receptor 1 isoform 3 precursor
           [Homo sapiens]
          Length = 733

 Score = 1497 bits (3875), Expect = 0.0
 Identities = 731/733 (99%), Positives = 731/733 (99%), Gaps = 2/733 (0%)

Query: 1   MWSWKCLLFWAVLVTATLCTARPSPTLPEQDALPSSEDDDDDDDSSSEEKETDNTKPN-- 58
           MWSWKCLLFWAVLVTATLCTARPSPTLPEQDALPSSEDDDDDDDSSSEEKETDNTKPN  
Sbjct: 1   MWSWKCLLFWAVLVTATLCTARPSPTLPEQDALPSSEDDDDDDDSSSEEKETDNTKPNRM 60

Query: 59  PVAPYWTSPEKMEKKLHAVPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPDHRIGGYKVR 118
           PVAPYWTSPEKMEKKLHAVPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPDHRIGGYKVR
Sbjct: 61  PVAPYWTSPEKMEKKLHAVPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPDHRIGGYKVR 120

Query: 119 YATWSIIMDSVVPSDKGNYTCIVENEYGSINHTYQLDVVERSPHRPILQAGLPANKTVAL 178
           YATWSIIMDSVVPSDKGNYTCIVENEYGSINHTYQLDVVERSPHRPILQAGLPANKTVAL
Sbjct: 121 YATWSIIMDSVVPSDKGNYTCIVENEYGSINHTYQLDVVERSPHRPILQAGLPANKTVAL 180

Query: 179 GSNVEFMCKVYSDPQPHIQWLKHIEVNGSKIGPDNLPYVQILKTAGVNTTDKEMEVLHLR 238
           GSNVEFMCKVYSDPQPHIQWLKHIEVNGSKIGPDNLPYVQILKTAGVNTTDKEMEVLHLR
Sbjct: 181 GSNVEFMCKVYSDPQPHIQWLKHIEVNGSKIGPDNLPYVQILKTAGVNTTDKEMEVLHLR 240

Query: 239 NVSFEDAGEYTCLAGNSIGLSHHSAWLTVLEALEERPAVMTSPLYLEIIIYCTGAFLISC 298
           NVSFEDAGEYTCLAGNSIGLSHHSAWLTVLEALEERPAVMTSPLYLEIIIYCTGAFLISC
Sbjct: 241 NVSFEDAGEYTCLAGNSIGLSHHSAWLTVLEALEERPAVMTSPLYLEIIIYCTGAFLISC 300

Query: 299 MVGSVIVYKMKSGTKKSDFHSQMAVHKLAKSIPLRRQVTVSADSSASMNSGVLLVRPSRL 358
           MVGSVIVYKMKSGTKKSDFHSQMAVHKLAKSIPLRRQVTVSADSSASMNSGVLLVRPSRL
Sbjct: 301 MVGSVIVYKMKSGTKKSDFHSQMAVHKLAKSIPLRRQVTVSADSSASMNSGVLLVRPSRL 360

Query: 359 SSSGTPMLAGVSEYELPEDPRWELPRDRLVLGKPLGEGCFGQVVLAEAIGLDKDKPNRVT 418
           SSSGTPMLAGVSEYELPEDPRWELPRDRLVLGKPLGEGCFGQVVLAEAIGLDKDKPNRVT
Sbjct: 361 SSSGTPMLAGVSEYELPEDPRWELPRDRLVLGKPLGEGCFGQVVLAEAIGLDKDKPNRVT 420

Query: 419 KVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNL 478
           KVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNL
Sbjct: 421 KVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNL 480

Query: 479 REYLQARRPPGLEYCYNPSHNPEEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNV 538
           REYLQARRPPGLEYCYNPSHNPEEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNV
Sbjct: 481 REYLQARRPPGLEYCYNPSHNPEEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNV 540

Query: 539 LVTEDNVMKIADFGLARDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVL 598
           LVTEDNVMKIADFGLARDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVL
Sbjct: 541 LVTEDNVMKIADFGLARDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVL 600

Query: 599 LWEIFTLGGSPYPGVPVEELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQ 658
           LWEIFTLGGSPYPGVPVEELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQ
Sbjct: 601 LWEIFTLGGSPYPGVPVEELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQ 660

Query: 659 LVEDLDRIVALTSNQEYLDLSMPLDQYSPSFPDTRSSTCSSGEDSVFSHEPLPEEPCLPR 718
           LVEDLDRIVALTSNQEYLDLSMPLDQYSPSFPDTRSSTCSSGEDSVFSHEPLPEEPCLPR
Sbjct: 661 LVEDLDRIVALTSNQEYLDLSMPLDQYSPSFPDTRSSTCSSGEDSVFSHEPLPEEPCLPR 720

Query: 719 HPAQLANGGLKRR 731
           HPAQLANGGLKRR
Sbjct: 721 HPAQLANGGLKRR 733


>gi|13186251 fibroblast growth factor receptor 1 isoform 2 precursor
           [Homo sapiens]
          Length = 820

 Score = 1436 bits (3717), Expect = 0.0
 Identities = 701/701 (100%), Positives = 701/701 (100%)

Query: 31  DALPSSEDDDDDDDSSSEEKETDNTKPNPVAPYWTSPEKMEKKLHAVPAAKTVKFKCPSS 90
           DALPSSEDDDDDDDSSSEEKETDNTKPNPVAPYWTSPEKMEKKLHAVPAAKTVKFKCPSS
Sbjct: 120 DALPSSEDDDDDDDSSSEEKETDNTKPNPVAPYWTSPEKMEKKLHAVPAAKTVKFKCPSS 179

Query: 91  GTPNPTLRWLKNGKEFKPDHRIGGYKVRYATWSIIMDSVVPSDKGNYTCIVENEYGSINH 150
           GTPNPTLRWLKNGKEFKPDHRIGGYKVRYATWSIIMDSVVPSDKGNYTCIVENEYGSINH
Sbjct: 180 GTPNPTLRWLKNGKEFKPDHRIGGYKVRYATWSIIMDSVVPSDKGNYTCIVENEYGSINH 239

Query: 151 TYQLDVVERSPHRPILQAGLPANKTVALGSNVEFMCKVYSDPQPHIQWLKHIEVNGSKIG 210
           TYQLDVVERSPHRPILQAGLPANKTVALGSNVEFMCKVYSDPQPHIQWLKHIEVNGSKIG
Sbjct: 240 TYQLDVVERSPHRPILQAGLPANKTVALGSNVEFMCKVYSDPQPHIQWLKHIEVNGSKIG 299

Query: 211 PDNLPYVQILKTAGVNTTDKEMEVLHLRNVSFEDAGEYTCLAGNSIGLSHHSAWLTVLEA 270
           PDNLPYVQILKTAGVNTTDKEMEVLHLRNVSFEDAGEYTCLAGNSIGLSHHSAWLTVLEA
Sbjct: 300 PDNLPYVQILKTAGVNTTDKEMEVLHLRNVSFEDAGEYTCLAGNSIGLSHHSAWLTVLEA 359

Query: 271 LEERPAVMTSPLYLEIIIYCTGAFLISCMVGSVIVYKMKSGTKKSDFHSQMAVHKLAKSI 330
           LEERPAVMTSPLYLEIIIYCTGAFLISCMVGSVIVYKMKSGTKKSDFHSQMAVHKLAKSI
Sbjct: 360 LEERPAVMTSPLYLEIIIYCTGAFLISCMVGSVIVYKMKSGTKKSDFHSQMAVHKLAKSI 419

Query: 331 PLRRQVTVSADSSASMNSGVLLVRPSRLSSSGTPMLAGVSEYELPEDPRWELPRDRLVLG 390
           PLRRQVTVSADSSASMNSGVLLVRPSRLSSSGTPMLAGVSEYELPEDPRWELPRDRLVLG
Sbjct: 420 PLRRQVTVSADSSASMNSGVLLVRPSRLSSSGTPMLAGVSEYELPEDPRWELPRDRLVLG 479

Query: 391 KPLGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISEMEMMKMIGKH 450
           KPLGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISEMEMMKMIGKH
Sbjct: 480 KPLGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISEMEMMKMIGKH 539

Query: 451 KNIINLLGACTQDGPLYVIVEYASKGNLREYLQARRPPGLEYCYNPSHNPEEQLSSKDLV 510
           KNIINLLGACTQDGPLYVIVEYASKGNLREYLQARRPPGLEYCYNPSHNPEEQLSSKDLV
Sbjct: 540 KNIINLLGACTQDGPLYVIVEYASKGNLREYLQARRPPGLEYCYNPSHNPEEQLSSKDLV 599

Query: 511 SCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHHIDYYKKTTNGR 570
           SCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHHIDYYKKTTNGR
Sbjct: 600 SCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHHIDYYKKTTNGR 659

Query: 571 LPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVEELFKLLKEGHRMDK 630
           LPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVEELFKLLKEGHRMDK
Sbjct: 660 LPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVEELFKLLKEGHRMDK 719

Query: 631 PSNCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRIVALTSNQEYLDLSMPLDQYSPSFP 690
           PSNCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRIVALTSNQEYLDLSMPLDQYSPSFP
Sbjct: 720 PSNCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRIVALTSNQEYLDLSMPLDQYSPSFP 779

Query: 691 DTRSSTCSSGEDSVFSHEPLPEEPCLPRHPAQLANGGLKRR 731
           DTRSSTCSSGEDSVFSHEPLPEEPCLPRHPAQLANGGLKRR
Sbjct: 780 DTRSSTCSSGEDSVFSHEPLPEEPCLPRHPAQLANGGLKRR 820



 Score =  101 bits (252), Expect = 2e-21
 Identities = 82/303 (27%), Positives = 118/303 (38%), Gaps = 78/303 (25%)

Query: 1   MWSWKCLLFWAVLVTATLCTARPSPTLPEQDALPSSEDDDDDDDSSSEEKETDNTKPNPV 60
           MWSWKCLLFWAVLVTATLCTARPSPTLPEQ                              
Sbjct: 1   MWSWKCLLFWAVLVTATLCTARPSPTLPEQ------------------------------ 30

Query: 61  APYWTSPEKMEKKLHAVPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPDHRIGGYKVRYA 120
           A  W +P ++E  L  V     ++ +C        ++ WL++G +    +R      R  
Sbjct: 31  AQPWGAPVEVESFL--VHPGDLLQLRCRLRDDVQ-SINWLRDGVQLAESNR-----TRIT 82

Query: 121 TWSIIMDSVVPSDKGNYTCIVENEYGSINHTYQLDVVERSPH------------------ 162
              + +   VP+D G Y C+  +  GS    + ++V +  P                   
Sbjct: 83  GEEVEVQDSVPADSGLYACVTSSPSGSDTTYFSVNVSDALPSSEDDDDDDDSSSEEKETD 142

Query: 163 ----RPILQAGLPANK------TVALGSNVEFMCKVYSDPQPHIQWLKHIEVNGSKIGPD 212
                P+        K       V     V+F C     P P ++WLK    NG +  PD
Sbjct: 143 NTKPNPVAPYWTSPEKMEKKLHAVPAAKTVKFKCPSSGTPNPTLRWLK----NGKEFKPD 198

Query: 213 NLPYVQILKTAGVNTTDKEMEVLHLRNVSFEDAGEYTCLAGNSIGLSHHSAWLTVLEALE 272
           +       +  G         ++ + +V   D G YTC+  N  G  +H+  L V+E   
Sbjct: 199 H-------RIGGYKVRYATWSII-MDSVVPSDKGNYTCIVENEYGSINHTYQLDVVERSP 250

Query: 273 ERP 275
            RP
Sbjct: 251 HRP 253


>gi|105990522 fibroblast growth factor receptor 1 isoform 1
           precursor [Homo sapiens]
          Length = 822

 Score = 1431 bits (3704), Expect = 0.0
 Identities = 701/703 (99%), Positives = 701/703 (99%), Gaps = 2/703 (0%)

Query: 31  DALPSSEDDDDDDDSSSEEKETDNTKPN--PVAPYWTSPEKMEKKLHAVPAAKTVKFKCP 88
           DALPSSEDDDDDDDSSSEEKETDNTKPN  PVAPYWTSPEKMEKKLHAVPAAKTVKFKCP
Sbjct: 120 DALPSSEDDDDDDDSSSEEKETDNTKPNRMPVAPYWTSPEKMEKKLHAVPAAKTVKFKCP 179

Query: 89  SSGTPNPTLRWLKNGKEFKPDHRIGGYKVRYATWSIIMDSVVPSDKGNYTCIVENEYGSI 148
           SSGTPNPTLRWLKNGKEFKPDHRIGGYKVRYATWSIIMDSVVPSDKGNYTCIVENEYGSI
Sbjct: 180 SSGTPNPTLRWLKNGKEFKPDHRIGGYKVRYATWSIIMDSVVPSDKGNYTCIVENEYGSI 239

Query: 149 NHTYQLDVVERSPHRPILQAGLPANKTVALGSNVEFMCKVYSDPQPHIQWLKHIEVNGSK 208
           NHTYQLDVVERSPHRPILQAGLPANKTVALGSNVEFMCKVYSDPQPHIQWLKHIEVNGSK
Sbjct: 240 NHTYQLDVVERSPHRPILQAGLPANKTVALGSNVEFMCKVYSDPQPHIQWLKHIEVNGSK 299

Query: 209 IGPDNLPYVQILKTAGVNTTDKEMEVLHLRNVSFEDAGEYTCLAGNSIGLSHHSAWLTVL 268
           IGPDNLPYVQILKTAGVNTTDKEMEVLHLRNVSFEDAGEYTCLAGNSIGLSHHSAWLTVL
Sbjct: 300 IGPDNLPYVQILKTAGVNTTDKEMEVLHLRNVSFEDAGEYTCLAGNSIGLSHHSAWLTVL 359

Query: 269 EALEERPAVMTSPLYLEIIIYCTGAFLISCMVGSVIVYKMKSGTKKSDFHSQMAVHKLAK 328
           EALEERPAVMTSPLYLEIIIYCTGAFLISCMVGSVIVYKMKSGTKKSDFHSQMAVHKLAK
Sbjct: 360 EALEERPAVMTSPLYLEIIIYCTGAFLISCMVGSVIVYKMKSGTKKSDFHSQMAVHKLAK 419

Query: 329 SIPLRRQVTVSADSSASMNSGVLLVRPSRLSSSGTPMLAGVSEYELPEDPRWELPRDRLV 388
           SIPLRRQVTVSADSSASMNSGVLLVRPSRLSSSGTPMLAGVSEYELPEDPRWELPRDRLV
Sbjct: 420 SIPLRRQVTVSADSSASMNSGVLLVRPSRLSSSGTPMLAGVSEYELPEDPRWELPRDRLV 479

Query: 389 LGKPLGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISEMEMMKMIG 448
           LGKPLGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISEMEMMKMIG
Sbjct: 480 LGKPLGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISEMEMMKMIG 539

Query: 449 KHKNIINLLGACTQDGPLYVIVEYASKGNLREYLQARRPPGLEYCYNPSHNPEEQLSSKD 508
           KHKNIINLLGACTQDGPLYVIVEYASKGNLREYLQARRPPGLEYCYNPSHNPEEQLSSKD
Sbjct: 540 KHKNIINLLGACTQDGPLYVIVEYASKGNLREYLQARRPPGLEYCYNPSHNPEEQLSSKD 599

Query: 509 LVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHHIDYYKKTTN 568
           LVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHHIDYYKKTTN
Sbjct: 600 LVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHHIDYYKKTTN 659

Query: 569 GRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVEELFKLLKEGHRM 628
           GRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVEELFKLLKEGHRM
Sbjct: 660 GRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVEELFKLLKEGHRM 719

Query: 629 DKPSNCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRIVALTSNQEYLDLSMPLDQYSPS 688
           DKPSNCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRIVALTSNQEYLDLSMPLDQYSPS
Sbjct: 720 DKPSNCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRIVALTSNQEYLDLSMPLDQYSPS 779

Query: 689 FPDTRSSTCSSGEDSVFSHEPLPEEPCLPRHPAQLANGGLKRR 731
           FPDTRSSTCSSGEDSVFSHEPLPEEPCLPRHPAQLANGGLKRR
Sbjct: 780 FPDTRSSTCSSGEDSVFSHEPLPEEPCLPRHPAQLANGGLKRR 822



 Score =  100 bits (250), Expect = 4e-21
 Identities = 82/305 (26%), Positives = 118/305 (38%), Gaps = 80/305 (26%)

Query: 1   MWSWKCLLFWAVLVTATLCTARPSPTLPEQDALPSSEDDDDDDDSSSEEKETDNTKPNPV 60
           MWSWKCLLFWAVLVTATLCTARPSPTLPEQ                              
Sbjct: 1   MWSWKCLLFWAVLVTATLCTARPSPTLPEQ------------------------------ 30

Query: 61  APYWTSPEKMEKKLHAVPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPDHRIGGYKVRYA 120
           A  W +P ++E  L  V     ++ +C        ++ WL++G +    +R      R  
Sbjct: 31  AQPWGAPVEVESFL--VHPGDLLQLRCRLRDDVQ-SINWLRDGVQLAESNR-----TRIT 82

Query: 121 TWSIIMDSVVPSDKGNYTCIVENEYGSINHTYQLDVVERSP------------------- 161
              + +   VP+D G Y C+  +  GS    + ++V +  P                   
Sbjct: 83  GEEVEVQDSVPADSGLYACVTSSPSGSDTTYFSVNVSDALPSSEDDDDDDDSSSEEKETD 142

Query: 162 -----HRPILQAGLPANK------TVALGSNVEFMCKVYSDPQPHIQWLKHIEVNGSKIG 210
                  P+        K       V     V+F C     P P ++WLK    NG +  
Sbjct: 143 NTKPNRMPVAPYWTSPEKMEKKLHAVPAAKTVKFKCPSSGTPNPTLRWLK----NGKEFK 198

Query: 211 PDNLPYVQILKTAGVNTTDKEMEVLHLRNVSFEDAGEYTCLAGNSIGLSHHSAWLTVLEA 270
           PD+       +  G         ++ + +V   D G YTC+  N  G  +H+  L V+E 
Sbjct: 199 PDH-------RIGGYKVRYATWSII-MDSVVPSDKGNYTCIVENEYGSINHTYQLDVVER 250

Query: 271 LEERP 275
              RP
Sbjct: 251 SPHRP 255


>gi|13186249 fibroblast growth factor receptor 1 isoform 9 precursor
           [Homo sapiens]
          Length = 785

 Score = 1331 bits (3444), Expect = 0.0
 Identities = 664/703 (94%), Positives = 664/703 (94%), Gaps = 39/703 (5%)

Query: 31  DALPSSEDDDDDDDSSSEEKETDNTKPN--PVAPYWTSPEKMEKKLHAVPAAKTVKFKCP 88
           DALPSSEDDDDDDDSSSEEKETDNTKPN  PVAPYWTSPEKMEKKLHAVPAAKTVKFKCP
Sbjct: 120 DALPSSEDDDDDDDSSSEEKETDNTKPNRMPVAPYWTSPEKMEKKLHAVPAAKTVKFKCP 179

Query: 89  SSGTPNPTLRWLKNGKEFKPDHRIGGYKVRYATWSIIMDSVVPSDKGNYTCIVENEYGSI 148
           SSGTPNPTLRWLKNGKEFKPDHRIGGYKVRYATWSIIMDSVVPSDKGNYTCIVENEYGSI
Sbjct: 180 SSGTPNPTLRWLKNGKEFKPDHRIGGYKVRYATWSIIMDSVVPSDKGNYTCIVENEYGSI 239

Query: 149 NHTYQLDVVERSPHRPILQAGLPANKTVALGSNVEFMCKVYSDPQPHIQWLKHIEVNGSK 208
           NHTYQLDVVERSPHRPILQAGLPANKTVALGSNVEFMCKVYSDPQPHIQWLKHIEVNGSK
Sbjct: 240 NHTYQLDVVERSPHRPILQAGLPANKTVALGSNVEFMCKVYSDPQPHIQWLKHIEVNGSK 299

Query: 209 IGPDNLPYVQILKTAGVNTTDKEMEVLHLRNVSFEDAGEYTCLAGNSIGLSHHSAWLTVL 268
           IGPDNLPYVQILKTAGVNTTDKEMEVLHLRNVSFEDAGEYTCLAGNSIGLSHHSAWLTVL
Sbjct: 300 IGPDNLPYVQILKTAGVNTTDKEMEVLHLRNVSFEDAGEYTCLAGNSIGLSHHSAWLTVL 359

Query: 269 EALEERPAVMTSPLYLEIIIYCTGAFLISCMVGSVIVYKMKSGTKKSDFHSQMAVHKLAK 328
           EALEERPAVMTSPLYLEIIIYCTGAFLISCMVGSVIVYKMKSGTKKSDFHSQMAVHKLAK
Sbjct: 360 EALEERPAVMTSPLYLEIIIYCTGAFLISCMVGSVIVYKMKSGTKKSDFHSQMAVHKLAK 419

Query: 329 SIPLRRQVTVSADSSASMNSGVLLVRPSRLSSSGTPMLAGVSEYELPEDPRWELPRDRLV 388
           SIPLRRQVTVSADSSASMNSGVLLVRPSRLSSSGTPMLAGVSEYELPEDPRWELPRDRLV
Sbjct: 420 SIPLRRQVTVSADSSASMNSGVLLVRPSRLSSSGTPMLAGVSEYELPEDPRWELPRDRLV 479

Query: 389 LGKPLGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISEMEMMKMIG 448
           LGKPLGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISEMEMMKMIG
Sbjct: 480 LGKPLGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISEMEMMKMIG 539

Query: 449 KHKNIINLLGACTQDGPLYVIVEYASKGNLREYLQARRPPGLEYCYNPSHNPEEQLSSKD 508
           KHKNIINLLGACTQDGPLYVIVEYASKGNLREYLQARRPPGLEYCYNPSHNPEEQLSSKD
Sbjct: 540 KHKNIINLLGACTQDGPLYVIVEYASKGNLREYLQARRPPGLEYCYNPSHNPEEQLSSKD 599

Query: 509 LVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHHIDYYKKTTN 568
           LVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHHIDYYKKTTN
Sbjct: 600 LVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHHIDYYKKTTN 659

Query: 569 GRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVEELFKLLKEGHRM 628
           GRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVEEL          
Sbjct: 660 GRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVEEL---------- 709

Query: 629 DKPSNCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRIVALTSNQEYLDLSMPLDQYSPS 688
                                      FKQLVEDLDRIVALTSNQEYLDLSMPLDQYSPS
Sbjct: 710 ---------------------------FKQLVEDLDRIVALTSNQEYLDLSMPLDQYSPS 742

Query: 689 FPDTRSSTCSSGEDSVFSHEPLPEEPCLPRHPAQLANGGLKRR 731
           FPDTRSSTCSSGEDSVFSHEPLPEEPCLPRHPAQLANGGLKRR
Sbjct: 743 FPDTRSSTCSSGEDSVFSHEPLPEEPCLPRHPAQLANGGLKRR 785



 Score =  100 bits (250), Expect = 4e-21
 Identities = 82/305 (26%), Positives = 118/305 (38%), Gaps = 80/305 (26%)

Query: 1   MWSWKCLLFWAVLVTATLCTARPSPTLPEQDALPSSEDDDDDDDSSSEEKETDNTKPNPV 60
           MWSWKCLLFWAVLVTATLCTARPSPTLPEQ                              
Sbjct: 1   MWSWKCLLFWAVLVTATLCTARPSPTLPEQ------------------------------ 30

Query: 61  APYWTSPEKMEKKLHAVPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPDHRIGGYKVRYA 120
           A  W +P ++E  L  V     ++ +C        ++ WL++G +    +R      R  
Sbjct: 31  AQPWGAPVEVESFL--VHPGDLLQLRCRLRDDVQ-SINWLRDGVQLAESNR-----TRIT 82

Query: 121 TWSIIMDSVVPSDKGNYTCIVENEYGSINHTYQLDVVERSP------------------- 161
              + +   VP+D G Y C+  +  GS    + ++V +  P                   
Sbjct: 83  GEEVEVQDSVPADSGLYACVTSSPSGSDTTYFSVNVSDALPSSEDDDDDDDSSSEEKETD 142

Query: 162 -----HRPILQAGLPANK------TVALGSNVEFMCKVYSDPQPHIQWLKHIEVNGSKIG 210
                  P+        K       V     V+F C     P P ++WLK    NG +  
Sbjct: 143 NTKPNRMPVAPYWTSPEKMEKKLHAVPAAKTVKFKCPSSGTPNPTLRWLK----NGKEFK 198

Query: 211 PDNLPYVQILKTAGVNTTDKEMEVLHLRNVSFEDAGEYTCLAGNSIGLSHHSAWLTVLEA 270
           PD+       +  G         ++ + +V   D G YTC+  N  G  +H+  L V+E 
Sbjct: 199 PDH-------RIGGYKVRYATWSII-MDSVVPSDKGNYTCIVENEYGSINHTYQLDVVER 250

Query: 271 LEERP 275
              RP
Sbjct: 251 SPHRP 255


>gi|221316639 fibroblast growth factor receptor 2 isoform 1
           precursor [Homo sapiens]
          Length = 821

 Score = 1125 bits (2910), Expect = 0.0
 Identities = 544/701 (77%), Positives = 613/701 (87%), Gaps = 8/701 (1%)

Query: 31  DALPSSEDDDDDDDSSSEEKETDNTKPNPVAPYWTSPEKMEKKLHAVPAAKTVKFKCPSS 90
           DA+ S +D+DD D +     E  N K    APYWT+ EKMEK+LHAVPAA TVKF+CP+ 
Sbjct: 126 DAISSGDDEDDTDGAEDFVSENSNNKR---APYWTNTEKMEKRLHAVPAANTVKFRCPAG 182

Query: 91  GTPNPTLRWLKNGKEFKPDHRIGGYKVRYATWSIIMDSVVPSDKGNYTCIVENEYGSINH 150
           G P PT+RWLKNGKEFK +HRIGGYKVR   WS+IM+SVVPSDKGNYTC+VENEYGSINH
Sbjct: 183 GNPMPTMRWLKNGKEFKQEHRIGGYKVRNQHWSLIMESVVPSDKGNYTCVVENEYGSINH 242

Query: 151 TYQLDVVERSPHRPILQAGLPANKTVALGSNVEFMCKVYSDPQPHIQWLKHIEVNGSKIG 210
           TY LDVVERSPHRPILQAGLPAN +  +G +VEF+CKVYSD QPHIQW+KH+E NGSK G
Sbjct: 243 TYHLDVVERSPHRPILQAGLPANASTVVGGDVEFVCKVYSDAQPHIQWIKHVEKNGSKYG 302

Query: 211 PDNLPYVQILKTAGVNTTDKEMEVLHLRNVSFEDAGEYTCLAGNSIGLSHHSAWLTVLEA 270
           PD LPY+++LK AGVNTTDKE+EVL++RNV+FEDAGEYTCLAGNSIG+S HSAWLTVL A
Sbjct: 303 PDGLPYLKVLKAAGVNTTDKEIEVLYIRNVTFEDAGEYTCLAGNSIGISFHSAWLTVLPA 362

Query: 271 LEERPAVMTSPLYLEIIIYCTGAFLISCMVGSVIVYKMKSGTKKSDFHSQMAVHKLAKSI 330
                 +  SP YLEI IYC G FLI+CMV +VI+ +MK+ TKK DF SQ AVHKL K I
Sbjct: 363 PGREKEITASPDYLEIAIYCIGVFLIACMVVTVILCRMKNTTKKPDFSSQPAVHKLTKRI 422

Query: 331 PLRRQVTVSADSSASMNSGVLLVR-PSRLSSSG-TPMLAGVSEYELPEDPRWELPRDRLV 388
           PLRRQVTVSA+SS+SMNS   LVR  +RLSS+  TPMLAGVSEYELPEDP+WE PRD+L 
Sbjct: 423 PLRRQVTVSAESSSSMNSNTPLVRITTRLSSTADTPMLAGVSEYELPEDPKWEFPRDKLT 482

Query: 389 LGKPLGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISEMEMMKMIG 448
           LGKPLGEGCFGQVV+AEA+G+DKDKP     VAVKMLK DATEKDLSDL+SEMEMMKMIG
Sbjct: 483 LGKPLGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLKDDATEKDLSDLVSEMEMMKMIG 542

Query: 449 KHKNIINLLGACTQDGPLYVIVEYASKGNLREYLQARRPPGLEYCYNPSHNPEEQLSSKD 508
           KHKNIINLLGACTQDGPLYVIVEYASKGNLREYL+ARRPPG+EY Y+ +  PEEQ++ KD
Sbjct: 543 KHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGMEYSYDINRVPEEQMTFKD 602

Query: 509 LVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHHIDYYKKTTN 568
           LVSC YQ+ARGMEYLAS+KCIHRDLAARNVLVTE+NVMKIADFGLARDI++IDYYKKTTN
Sbjct: 603 LVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDINNIDYYKKTTN 662

Query: 569 GRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVEELFKLLKEGHRM 628
           GRLPVKWMAPEALFDR+YTHQSDVWSFGVL+WEIFTLGGSPYPG+PVEELFKLLKEGHRM
Sbjct: 663 GRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEELFKLLKEGHRM 722

Query: 629 DKPSNCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRIVALTSNQEYLDLSMPLDQYSPS 688
           DKP+NCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRI+ LT+N+EYLDLS PL+QYSPS
Sbjct: 723 DKPANCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRILTLTTNEEYLDLSQPLEQYSPS 782

Query: 689 FPDTRSSTCSSGEDSVFSHEPLPEEPCLPRHPAQLANGGLK 729
           +PDTRSS CSSG+DSVFS +P+P EPCLP++P    NG +K
Sbjct: 783 YPDTRSS-CSSGDDSVFSPDPMPYEPCLPQYPH--INGSVK 820



 Score = 51.6 bits (122), Expect = 3e-06
 Identities = 63/303 (20%), Positives = 106/303 (34%), Gaps = 75/303 (24%)

Query: 1   MWSWKCLLFWAVLVTATLCTARPSPTLPEQDALPSSEDDDDDDDSSSEEKETDNTKPNPV 60
           M SW   +   V+  ATL  ARPS +L E   L   E                     P 
Sbjct: 1   MVSWGRFICLVVVTMATLSLARPSFSLVEDTTLEPEE---------------------PP 39

Query: 61  APYWTSPEKMEKKLHAVPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPDHR---IGGYKV 117
             Y  S    + +++     ++++ +C         + W K+G    P++R   IG Y  
Sbjct: 40  TKYQIS----QPEVYVAAPGESLEVRCLLKDA--AVISWTKDGVHLGPNNRTVLIGEY-- 91

Query: 118 RYATWSIIMDSVVPSDKGNYTCIVENEYGSINHTYQLDVVE------------------- 158
                 + +    P D G Y C       S    + ++V +                   
Sbjct: 92  ------LQIKGATPRDSGLYACTASRTVDSETWYFMVNVTDAISSGDDEDDTDGAEDFVS 145

Query: 159 ------RSPHRPILQAGLPANKTVALGSNVEFMCKVYSDPQPHIQWLKHIEVNGSKIGPD 212
                 R+P+    +        V   + V+F C    +P P ++WLK    NG +    
Sbjct: 146 ENSNNKRAPYWTNTEKMEKRLHAVPAANTVKFRCPAGGNPMPTMRWLK----NGKE---- 197

Query: 213 NLPYVQILKTAGVNTTDKEMEVLHLRNVSFEDAGEYTCLAGNSIGLSHHSAWLTVLEALE 272
              + Q  +  G    ++   ++ + +V   D G YTC+  N  G  +H+  L V+E   
Sbjct: 198 ---FKQEHRIGGYKVRNQHWSLI-MESVVPSDKGNYTCVVENEYGSINHTYHLDVVERSP 253

Query: 273 ERP 275
            RP
Sbjct: 254 HRP 256


>gi|222144237 fibroblast growth factor receptor 2 isoform 6
           precursor [Homo sapiens]
          Length = 706

 Score = 1117 bits (2890), Expect = 0.0
 Identities = 549/731 (75%), Positives = 617/731 (84%), Gaps = 28/731 (3%)

Query: 1   MWSWKCLLFWAVLVTATLCTARPSPTLPEQDALPSSEDDDDDDDSSSEEKETDNTKPNPV 60
           M SW   +   V+  ATL  ARPS +L E                       D T     
Sbjct: 1   MVSWGRFICLVVVTMATLSLARPSFSLVE-----------------------DTTLEPEG 37

Query: 61  APYWTSPEKMEKKLHAVPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPDHRIGGYKVRYA 120
           APYWT+ EKMEK+LHAVPAA TVKF+CP+ G P PT+RWLKNGKEFK +HRIGGYKVR  
Sbjct: 38  APYWTNTEKMEKRLHAVPAANTVKFRCPAGGNPMPTMRWLKNGKEFKQEHRIGGYKVRNQ 97

Query: 121 TWSIIMDSVVPSDKGNYTCIVENEYGSINHTYQLDVVERSPHRPILQAGLPANKTVALGS 180
            WS+IM+SVVPSDKGNYTC+VENEYGSINHTY LDVVERSPHRPILQAGLPAN +  +G 
Sbjct: 98  HWSLIMESVVPSDKGNYTCVVENEYGSINHTYHLDVVERSPHRPILQAGLPANASTVVGG 157

Query: 181 NVEFMCKVYSDPQPHIQWLKHIEVNGSKIGPDNLPYVQILKTAGVNTTDKEMEVLHLRNV 240
           +VEF+CKVYSD QPHIQW+KH+E NGSK GPD LPY+++LK AGVNTTDKE+EVL++RNV
Sbjct: 158 DVEFVCKVYSDAQPHIQWIKHVEKNGSKYGPDGLPYLKVLKAAGVNTTDKEIEVLYIRNV 217

Query: 241 SFEDAGEYTCLAGNSIGLSHHSAWLTVLEALEERPAVMTSPLYLEIIIYCTGAFLISCMV 300
           +FEDAGEYTCLAGNSIG+S HSAWLTVL A      +  SP YLEI IYC G FLI+CMV
Sbjct: 218 TFEDAGEYTCLAGNSIGISFHSAWLTVLPAPGREKEITASPDYLEIAIYCIGVFLIACMV 277

Query: 301 GSVIVYKMKSGTKKSDFHSQMAVHKLAKSIPLRRQVTVSADSSASMNSGVLLVR-PSRLS 359
            +VI+ +MK+ TKK DF SQ AVHKL K IPLRRQVTVSA+SS+SMNS   LVR  +RLS
Sbjct: 278 VTVILCRMKNTTKKPDFSSQPAVHKLTKRIPLRRQVTVSAESSSSMNSNTPLVRITTRLS 337

Query: 360 SSG-TPMLAGVSEYELPEDPRWELPRDRLVLGKPLGEGCFGQVVLAEAIGLDKDKPNRVT 418
           S+  TPMLAGVSEYELPEDP+WE PRD+L LGKPLGEGCFGQVV+AEA+G+DKDKP    
Sbjct: 338 STADTPMLAGVSEYELPEDPKWEFPRDKLTLGKPLGEGCFGQVVMAEAVGIDKDKPKEAV 397

Query: 419 KVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNL 478
            VAVKMLK DATEKDLSDL+SEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNL
Sbjct: 398 TVAVKMLKDDATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNL 457

Query: 479 REYLQARRPPGLEYCYNPSHNPEEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNV 538
           REYL+ARRPPG+EY Y+ +  PEEQ++ KDLVSC YQ+ARGMEYLAS+KCIHRDLAARNV
Sbjct: 458 REYLRARRPPGMEYSYDINRVPEEQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNV 517

Query: 539 LVTEDNVMKIADFGLARDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVL 598
           LVTE+NVMKIADFGLARDI++IDYYKKTTNGRLPVKWMAPEALFDR+YTHQSDVWSFGVL
Sbjct: 518 LVTENNVMKIADFGLARDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVL 577

Query: 599 LWEIFTLGGSPYPGVPVEELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQ 658
           +WEIFTLGGSPYPG+PVEELFKLLKEGHRMDKP+NCTNELYMMMRDCWHAVPSQRPTFKQ
Sbjct: 578 MWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTNELYMMMRDCWHAVPSQRPTFKQ 637

Query: 659 LVEDLDRIVALTSNQEYLDLSMPLDQYSPSFPDTRSSTCSSGEDSVFSHEPLPEEPCLPR 718
           LVEDLDRI+ LT+N+EYLDLS PL+QYSPS+PDTRSS CSSG+DSVFS +P+P EPCLP+
Sbjct: 638 LVEDLDRILTLTTNEEYLDLSQPLEQYSPSYPDTRSS-CSSGDDSVFSPDPMPYEPCLPQ 696

Query: 719 HPAQLANGGLK 729
           +P    NG +K
Sbjct: 697 YPH--INGSVK 705


>gi|222144241 fibroblast growth factor receptor 2 isoform 8
           precursor [Homo sapiens]
          Length = 704

 Score = 1109 bits (2868), Expect = 0.0
 Identities = 547/731 (74%), Positives = 615/731 (84%), Gaps = 30/731 (4%)

Query: 1   MWSWKCLLFWAVLVTATLCTARPSPTLPEQDALPSSEDDDDDDDSSSEEKETDNTKPNPV 60
           M SW   +   V+  ATL  ARPS +L E                       D T     
Sbjct: 1   MVSWGRFICLVVVTMATLSLARPSFSLVE-----------------------DTTLEPEG 37

Query: 61  APYWTSPEKMEKKLHAVPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPDHRIGGYKVRYA 120
           APYWT+ EKMEK+LHAVPAA TVKF+CP+ G P PT+RWLKNGKEFK +HRIGGYKVR  
Sbjct: 38  APYWTNTEKMEKRLHAVPAANTVKFRCPAGGNPMPTMRWLKNGKEFKQEHRIGGYKVRNQ 97

Query: 121 TWSIIMDSVVPSDKGNYTCIVENEYGSINHTYQLDVVERSPHRPILQAGLPANKTVALGS 180
            WS+IM+SVVPSDKGNYTC+VENEYGSINHTY LDVVERSPHRPILQAGLPAN +  +G 
Sbjct: 98  HWSLIMESVVPSDKGNYTCVVENEYGSINHTYHLDVVERSPHRPILQAGLPANASTVVGG 157

Query: 181 NVEFMCKVYSDPQPHIQWLKHIEVNGSKIGPDNLPYVQILKTAGVNTTDKEMEVLHLRNV 240
           +VEF+CKVYSD QPHIQW+KH+E NGSK GPD LPY+++LK AGVNTTDKE+EVL++RNV
Sbjct: 158 DVEFVCKVYSDAQPHIQWIKHVEKNGSKYGPDGLPYLKVLKAAGVNTTDKEIEVLYIRNV 217

Query: 241 SFEDAGEYTCLAGNSIGLSHHSAWLTVLEALEERPAVMTSPLYLEIIIYCTGAFLISCMV 300
           +FEDAGEYTCLAGNSIG+S HSAWLTVL A      +  SP YLEI IYC G FLI+CMV
Sbjct: 218 TFEDAGEYTCLAGNSIGISFHSAWLTVLPAPGREKEITASPDYLEIAIYCIGVFLIACMV 277

Query: 301 GSVIVYKMKSGTKKSDFHSQMAVHKLAKSIPLRRQVTVSADSSASMNSGVLLVR-PSRLS 359
            +VI+ +MK+ TKK DF SQ AVHKL K IPLRRQV  SA+SS+SMNS   LVR  +RLS
Sbjct: 278 VTVILCRMKNTTKKPDFSSQPAVHKLTKRIPLRRQV--SAESSSSMNSNTPLVRITTRLS 335

Query: 360 SSG-TPMLAGVSEYELPEDPRWELPRDRLVLGKPLGEGCFGQVVLAEAIGLDKDKPNRVT 418
           S+  TPMLAGVSEYELPEDP+WE PRD+L LGKPLGEGCFGQVV+AEA+G+DKDKP    
Sbjct: 336 STADTPMLAGVSEYELPEDPKWEFPRDKLTLGKPLGEGCFGQVVMAEAVGIDKDKPKEAV 395

Query: 419 KVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNL 478
            VAVKMLK DATEKDLSDL+SEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNL
Sbjct: 396 TVAVKMLKDDATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNL 455

Query: 479 REYLQARRPPGLEYCYNPSHNPEEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNV 538
           REYL+ARRPPG+EY Y+ +  PEEQ++ KDLVSC YQ+ARGMEYLAS+KCIHRDLAARNV
Sbjct: 456 REYLRARRPPGMEYSYDINRVPEEQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNV 515

Query: 539 LVTEDNVMKIADFGLARDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVL 598
           LVTE+NVMKIADFGLARDI++IDYYKKTTNGRLPVKWMAPEALFDR+YTHQSDVWSFGVL
Sbjct: 516 LVTENNVMKIADFGLARDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVL 575

Query: 599 LWEIFTLGGSPYPGVPVEELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQ 658
           +WEIFTLGGSPYPG+PVEELFKLLKEGHRMDKP+NCTNELYMMMRDCWHAVPSQRPTFKQ
Sbjct: 576 MWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTNELYMMMRDCWHAVPSQRPTFKQ 635

Query: 659 LVEDLDRIVALTSNQEYLDLSMPLDQYSPSFPDTRSSTCSSGEDSVFSHEPLPEEPCLPR 718
           LVEDLDRI+ LT+N+EYLDLS PL+QYSPS+PDTRSS CSSG+DSVFS +P+P EPCLP+
Sbjct: 636 LVEDLDRILTLTTNEEYLDLSQPLEQYSPSYPDTRSS-CSSGDDSVFSPDPMPYEPCLPQ 694

Query: 719 HPAQLANGGLK 729
           +P    NG +K
Sbjct: 695 YPH--INGSVK 703


>gi|221316638 fibroblast growth factor receptor 2 isoform 2
           precursor [Homo sapiens]
          Length = 822

 Score = 1078 bits (2789), Expect = 0.0
 Identities = 528/704 (75%), Positives = 601/704 (85%), Gaps = 13/704 (1%)

Query: 31  DALPSSEDDDDDDDSSSEEKETDNTKPNPVAPYWTSPEKMEKKLHAVPAAKTVKFKCPSS 90
           DA+ S +D+DD D +     E  N K    APYWT+ EKMEK+LHAVPAA TVKF+CP+ 
Sbjct: 126 DAISSGDDEDDTDGAEDFVSENSNNKR---APYWTNTEKMEKRLHAVPAANTVKFRCPAG 182

Query: 91  GTPNPTLRWLKNGKEFKPDHRIGGYKVRYATWSIIMDSVVPSDKGNYTCIVENEYGSINH 150
           G P PT+RWLKNGKEFK +HRIGGYKVR   WS+IM+SVVPSDKGNYTC+VENEYGSINH
Sbjct: 183 GNPMPTMRWLKNGKEFKQEHRIGGYKVRNQHWSLIMESVVPSDKGNYTCVVENEYGSINH 242

Query: 151 TYQLDVVERSPHRPILQAGLPANKTVALGSNVEFMCKVYSDPQPHIQWLKHIEVNGSKIG 210
           TY LDVVERSPHRPILQAGLPAN +  +G +VEF+CKVYSD QPHIQW+KH+E NGSK G
Sbjct: 243 TYHLDVVERSPHRPILQAGLPANASTVVGGDVEFVCKVYSDAQPHIQWIKHVEKNGSKYG 302

Query: 211 PDNLPYVQILKTAGVNTTDKEMEVLHLRNVSFEDAGEYTCLAGNSIGLSHHSAWLTVL-- 268
           PD LPY+++LK +G+N+++ E  VL L NV+  DAGEY C   N IG ++ SAWLTVL  
Sbjct: 303 PDGLPYLKVLKHSGINSSNAE--VLALFNVTEADAGEYICKVSNYIGQANQSAWLTVLPK 360

Query: 269 -EALEERPAVMTSPLYLEIIIYCTGAFLISCMVGSVIVYKMKSGTKKSDFHSQMAVHKLA 327
            +A      +  SP YLEI IYC G FLI+CMV +VI+ +MK+ TKK DF SQ AVHKL 
Sbjct: 361 QQAPGREKEITASPDYLEIAIYCIGVFLIACMVVTVILCRMKNTTKKPDFSSQPAVHKLT 420

Query: 328 KSIPLRRQVTVSADSSASMNSGVLLVR-PSRLSSSG-TPMLAGVSEYELPEDPRWELPRD 385
           K IPLRRQVTVSA+SS+SMNS   LVR  +RLSS+  TPMLAGVSEYELPEDP+WE PRD
Sbjct: 421 KRIPLRRQVTVSAESSSSMNSNTPLVRITTRLSSTADTPMLAGVSEYELPEDPKWEFPRD 480

Query: 386 RLVLGKPLGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISEMEMMK 445
           +L LGKPLGEGCFGQVV+AEA+G+DKDKP     VAVKMLK DATEKDLSDL+SEMEMMK
Sbjct: 481 KLTLGKPLGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLKDDATEKDLSDLVSEMEMMK 540

Query: 446 MIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLQARRPPGLEYCYNPSHNPEEQLS 505
           MIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYL+ARRPPG+EY Y+ +  PEEQ++
Sbjct: 541 MIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGMEYSYDINRVPEEQMT 600

Query: 506 SKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHHIDYYKK 565
            KDLVSC YQ+ARGMEYLAS+KCIHRDLAARNVLVTE+NVMKIADFGLARDI++IDYYKK
Sbjct: 601 FKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDINNIDYYKK 660

Query: 566 TTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVEELFKLLKEG 625
           TTNGRLPVKWMAPEALFDR+YTHQSDVWSFGVL+WEIFTLGGSPYPG+PVEELFKLLKEG
Sbjct: 661 TTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEELFKLLKEG 720

Query: 626 HRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRIVALTSNQEYLDLSMPLDQY 685
           HRMDKP+NCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRI+ LT+N+EYLDLS PL+QY
Sbjct: 721 HRMDKPANCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRILTLTTNEEYLDLSQPLEQY 780

Query: 686 SPSFPDTRSSTCSSGEDSVFSHEPLPEEPCLPRHPAQLANGGLK 729
           SPS+PDTRSS CSSG+DSVFS +P+P EPCLP++P    NG +K
Sbjct: 781 SPSYPDTRSS-CSSGDDSVFSPDPMPYEPCLPQYPH--INGSVK 821



 Score = 51.6 bits (122), Expect = 3e-06
 Identities = 63/303 (20%), Positives = 106/303 (34%), Gaps = 75/303 (24%)

Query: 1   MWSWKCLLFWAVLVTATLCTARPSPTLPEQDALPSSEDDDDDDDSSSEEKETDNTKPNPV 60
           M SW   +   V+  ATL  ARPS +L E   L   E                     P 
Sbjct: 1   MVSWGRFICLVVVTMATLSLARPSFSLVEDTTLEPEE---------------------PP 39

Query: 61  APYWTSPEKMEKKLHAVPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPDHR---IGGYKV 117
             Y  S    + +++     ++++ +C         + W K+G    P++R   IG Y  
Sbjct: 40  TKYQIS----QPEVYVAAPGESLEVRCLLKDA--AVISWTKDGVHLGPNNRTVLIGEY-- 91

Query: 118 RYATWSIIMDSVVPSDKGNYTCIVENEYGSINHTYQLDVVE------------------- 158
                 + +    P D G Y C       S    + ++V +                   
Sbjct: 92  ------LQIKGATPRDSGLYACTASRTVDSETWYFMVNVTDAISSGDDEDDTDGAEDFVS 145

Query: 159 ------RSPHRPILQAGLPANKTVALGSNVEFMCKVYSDPQPHIQWLKHIEVNGSKIGPD 212
                 R+P+    +        V   + V+F C    +P P ++WLK    NG +    
Sbjct: 146 ENSNNKRAPYWTNTEKMEKRLHAVPAANTVKFRCPAGGNPMPTMRWLK----NGKE---- 197

Query: 213 NLPYVQILKTAGVNTTDKEMEVLHLRNVSFEDAGEYTCLAGNSIGLSHHSAWLTVLEALE 272
              + Q  +  G    ++   ++ + +V   D G YTC+  N  G  +H+  L V+E   
Sbjct: 198 ---FKQEHRIGGYKVRNQHWSLI-MESVVPSDKGNYTCVVENEYGSINHTYHLDVVERSP 253

Query: 273 ERP 275
            RP
Sbjct: 254 HRP 256


>gi|222144235 fibroblast growth factor receptor 2 isoform 5
           precursor [Homo sapiens]
          Length = 707

 Score = 1068 bits (2761), Expect = 0.0
 Identities = 522/695 (75%), Positives = 589/695 (84%), Gaps = 11/695 (1%)

Query: 1   MWSWKCLLFWAVLVTATLCTARPS------PTLPEQDALPSSEDDDDDDDSSSEEKETDN 54
           M SW   +   V+  ATL  ARPS       TL  +DA+ S +D+DD D +     E  N
Sbjct: 1   MVSWGRFICLVVVTMATLSLARPSFSLVEDTTLEPEDAISSGDDEDDTDGAEDFVSENSN 60

Query: 55  TKPNPVAPYWTSPEKMEKKLHAVPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPDHRIGG 114
            K    APYWT+ EKMEK+LHAVPAA TVKF+CP+ G P PT+RWLKNGKEFK +HRIGG
Sbjct: 61  NKR---APYWTNTEKMEKRLHAVPAANTVKFRCPAGGNPMPTMRWLKNGKEFKQEHRIGG 117

Query: 115 YKVRYATWSIIMDSVVPSDKGNYTCIVENEYGSINHTYQLDVVERSPHRPILQAGLPANK 174
           YKVR   WS+IM+SVVPSDKGNYTC+VENEYGSINHTY LDVVERSPHRPILQAGLPAN 
Sbjct: 118 YKVRNQHWSLIMESVVPSDKGNYTCVVENEYGSINHTYHLDVVERSPHRPILQAGLPANA 177

Query: 175 TVALGSNVEFMCKVYSDPQPHIQWLKHIEVNGSKIGPDNLPYVQILKTAGVNTTDKEMEV 234
           +  +G +VEF+CKVYSD QPHIQW+KH+E NGSK GPD LPY+++LK AGVNTTDKE+EV
Sbjct: 178 STVVGGDVEFVCKVYSDAQPHIQWIKHVEKNGSKYGPDGLPYLKVLKAAGVNTTDKEIEV 237

Query: 235 LHLRNVSFEDAGEYTCLAGNSIGLSHHSAWLTVLEALEERPAVMTSPLYLEIIIYCTGAF 294
           L++RNV+FEDAGEYTCLAGNSIG+S HSAWLTVL A      +  SP YLEI IYC G F
Sbjct: 238 LYIRNVTFEDAGEYTCLAGNSIGISFHSAWLTVLPAPGREKEITASPDYLEIAIYCIGVF 297

Query: 295 LISCMVGSVIVYKMKSGTKKSDFHSQMAVHKLAKSIPLRRQVTVSADSSASMNSGVLLVR 354
           LI+CMV +VI+ +MK+ TKK DF SQ AVHKL K IPLRRQVTVSA+SS+SMNS   LVR
Sbjct: 298 LIACMVVTVILCRMKNTTKKPDFSSQPAVHKLTKRIPLRRQVTVSAESSSSMNSNTPLVR 357

Query: 355 -PSRLSSSG-TPMLAGVSEYELPEDPRWELPRDRLVLGKPLGEGCFGQVVLAEAIGLDKD 412
             +RLSS+  TPMLAGVSEYELPEDP+WE PRD+L LGKPLGEGCFGQVV+AEA+G+DKD
Sbjct: 358 ITTRLSSTADTPMLAGVSEYELPEDPKWEFPRDKLTLGKPLGEGCFGQVVMAEAVGIDKD 417

Query: 413 KPNRVTKVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEY 472
           KP     VAVKMLK DATEKDLSDL+SEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEY
Sbjct: 418 KPKEAVTVAVKMLKDDATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEY 477

Query: 473 ASKGNLREYLQARRPPGLEYCYNPSHNPEEQLSSKDLVSCAYQVARGMEYLASKKCIHRD 532
           ASKGNLREYL+ARRPPG+EY Y+ +  PEEQ++ KDLVSC YQ+ARGMEYLAS+KCIHRD
Sbjct: 478 ASKGNLREYLRARRPPGMEYSYDINRVPEEQMTFKDLVSCTYQLARGMEYLASQKCIHRD 537

Query: 533 LAARNVLVTEDNVMKIADFGLARDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDV 592
           LAARNVLVTE+NVMKIADFGLARDI++IDYYKKTTNGRLPVKWMAPEALFDR+YTHQSDV
Sbjct: 538 LAARNVLVTENNVMKIADFGLARDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDV 597

Query: 593 WSFGVLLWEIFTLGGSPYPGVPVEELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQ 652
           WSFGVL+WEIFTLGGSPYPG+PVEELFKLLKEGHRMDKP+NCTNELYMMMRDCWHAVPSQ
Sbjct: 598 WSFGVLMWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTNELYMMMRDCWHAVPSQ 657

Query: 653 RPTFKQLVEDLDRIVALTSNQEYLDLSMPLDQYSP 687
           RPTFKQLVEDLDRI+ LT+N+E   +S  +D + P
Sbjct: 658 RPTFKQLVEDLDRILTLTTNEEEKKVSGAVDCHKP 692


>gi|222144244 fibroblast growth factor receptor 2 isoform 9
           precursor [Homo sapiens]
          Length = 680

 Score = 1016 bits (2626), Expect = 0.0
 Identities = 502/684 (73%), Positives = 570/684 (83%), Gaps = 16/684 (2%)

Query: 1   MWSWKCLLFWAVLVTATLCTARPS------PTLPEQDALPSSEDDDDDDDSSSEEKETDN 54
           M SW   +   V+  ATL  ARPS       TL  +DA+ S +D+DD D +     E  N
Sbjct: 1   MVSWGRFICLVVVTMATLSLARPSFSLVEDTTLEPEDAISSGDDEDDTDGAEDFVSENSN 60

Query: 55  TKPNPVAPYWTSPEKMEKKLHAVPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPDHRIGG 114
            K    APYWT+ EKMEK+LHAVPAA TVKF+CP+ G P PT+RWLKNGKEFK +HRIGG
Sbjct: 61  NKR---APYWTNTEKMEKRLHAVPAANTVKFRCPAGGNPMPTMRWLKNGKEFKQEHRIGG 117

Query: 115 YKVRYATWSIIMDSVVPSDKGNYTCIVENEYGSINHTYQLDVVERSPHRPILQAGLPANK 174
           YKVR   WS+IM+SVVPSDKGNYTC+VENEYGSINHTY LDVVERSPHRPILQAGLPAN 
Sbjct: 118 YKVRNQHWSLIMESVVPSDKGNYTCVVENEYGSINHTYHLDVVERSPHRPILQAGLPANA 177

Query: 175 TVALGSNVEFMCKVYSDPQPHIQWLKHIEVNGSKIGPDNLPYVQILKTAGVNTTDKEMEV 234
           +  +G +VEF+CKVYSD QPHIQW+KH+E NGSK GPD LPY+++LK +G+N+++ E  V
Sbjct: 178 STVVGGDVEFVCKVYSDAQPHIQWIKHVEKNGSKYGPDGLPYLKVLKHSGINSSNAE--V 235

Query: 235 LHLRNVSFEDAGEYTCLAGNSIGLSHHSAWLTVL---EALEERPAVMTSPLYLEIIIYCT 291
           L L NV+  DAGEY C   N IG ++ SAWLTVL   +A      +  SP YLEI IYC 
Sbjct: 236 LALFNVTEADAGEYICKVSNYIGQANQSAWLTVLPKQQAPGREKEITASPDYLEIAIYCI 295

Query: 292 GAFLISCMVGSVIVYKMKSGTKKSDFHSQMAVHKLAKSIPLRRQVTVSADSSASMNSGVL 351
           G FLI+CMV +VI+ +MK+ TKK DF SQ AVHKL K IPLRRQVTVSA+SS+SMNS   
Sbjct: 296 GVFLIACMVVTVILCRMKNTTKKPDFSSQPAVHKLTKRIPLRRQVTVSAESSSSMNSNTP 355

Query: 352 LVR-PSRLSSSG-TPMLAGVSEYELPEDPRWELPRDRLVLGKPLGEGCFGQVVLAEAIGL 409
           LVR  +RLSS+  TPMLAGVSEYELPEDP+WE PRD+L LGKPLGEGCFGQVV+AEA+G+
Sbjct: 356 LVRITTRLSSTADTPMLAGVSEYELPEDPKWEFPRDKLTLGKPLGEGCFGQVVMAEAVGI 415

Query: 410 DKDKPNRVTKVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVI 469
           DKDKP     VAVKMLK DATEKDLSDL+SEMEMMKMIGKHKNIINLLGACTQDGPLYVI
Sbjct: 416 DKDKPKEAVTVAVKMLKDDATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVI 475

Query: 470 VEYASKGNLREYLQARRPPGLEYCYNPSHNPEEQLSSKDLVSCAYQVARGMEYLASKKCI 529
           VEYASKGNLREYL+ARRPPG+EY Y+ +  PEEQ++ KDLVSC YQ+ARGMEYLAS+KCI
Sbjct: 476 VEYASKGNLREYLRARRPPGMEYSYDINRVPEEQMTFKDLVSCTYQLARGMEYLASQKCI 535

Query: 530 HRDLAARNVLVTEDNVMKIADFGLARDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQ 589
           HRDLAARNVLVTE+NVMKIADFGLARDI++IDYYKKTTNGRLPVKWMAPEALFDR+YTHQ
Sbjct: 536 HRDLAARNVLVTENNVMKIADFGLARDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQ 595

Query: 590 SDVWSFGVLLWEIFTLGGSPYPGVPVEELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAV 649
           SDVWSFGVL+WEIFTLGGSPYPG+PVEELFKLLKEGHRMDKP+NCTNELYMMMRDCWHAV
Sbjct: 596 SDVWSFGVLMWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTNELYMMMRDCWHAV 655

Query: 650 PSQRPTFKQLVEDLDRIVALTSNQ 673
           PSQRPTFKQLVEDLDRI+ LT+N+
Sbjct: 656 PSQRPTFKQLVEDLDRILTLTTNE 679


>gi|222144231 fibroblast growth factor receptor 2 isoform 3
           precursor [Homo sapiens]
          Length = 769

 Score = 1002 bits (2590), Expect = 0.0
 Identities = 489/648 (75%), Positives = 554/648 (85%), Gaps = 10/648 (1%)

Query: 31  DALPSSEDDDDDDDSSSEEKETDNTKPNPVAPYWTSPEKMEKKLHAVPAAKTVKFKCPSS 90
           DA+ S +D+DD D +     E  N K    APYWT+ EKMEK+LHAVPAA TVKF+CP+ 
Sbjct: 126 DAISSGDDEDDTDGAEDFVSENSNNKR---APYWTNTEKMEKRLHAVPAANTVKFRCPAG 182

Query: 91  GTPNPTLRWLKNGKEFKPDHRIGGYKVRYATWSIIMDSVVPSDKGNYTCIVENEYGSINH 150
           G P PT+RWLKNGKEFK +HRIGGYKVR   WS+IM+SVVPSDKGNYTC+VENEYGSINH
Sbjct: 183 GNPMPTMRWLKNGKEFKQEHRIGGYKVRNQHWSLIMESVVPSDKGNYTCVVENEYGSINH 242

Query: 151 TYQLDVVERSPHRPILQAGLPANKTVALGSNVEFMCKVYSDPQPHIQWLKHIEVNGSKIG 210
           TY LDVVERSPHRPILQAGLPAN +  +G +VEF+CKVYSD QPHIQW+KH+E NGSK G
Sbjct: 243 TYHLDVVERSPHRPILQAGLPANASTVVGGDVEFVCKVYSDAQPHIQWIKHVEKNGSKYG 302

Query: 211 PDNLPYVQILKTAGVNTTDKEMEVLHLRNVSFEDAGEYTCLAGNSIGLSHHSAWLTVL-- 268
           PD LPY+++LK +G+N+++ E  VL L NV+  DAGEY C   N IG ++ SAWLTVL  
Sbjct: 303 PDGLPYLKVLKHSGINSSNAE--VLALFNVTEADAGEYICKVSNYIGQANQSAWLTVLPK 360

Query: 269 -EALEERPAVMTSPLYLEIIIYCTGAFLISCMVGSVIVYKMKSGTKKSDFHSQMAVHKLA 327
            +A      +  SP YLEI IYC G FLI+CMV +VI+ +MK+ TKK DF SQ AVHKL 
Sbjct: 361 QQAPGREKEITASPDYLEIAIYCIGVFLIACMVVTVILCRMKNTTKKPDFSSQPAVHKLT 420

Query: 328 KSIPLRRQVTVSADSSASMNSGVLLVR-PSRLSSSG-TPMLAGVSEYELPEDPRWELPRD 385
           K IPLRRQVTVSA+SS+SMNS   LVR  +RLSS+  TPMLAGVSEYELPEDP+WE PRD
Sbjct: 421 KRIPLRRQVTVSAESSSSMNSNTPLVRITTRLSSTADTPMLAGVSEYELPEDPKWEFPRD 480

Query: 386 RLVLGKPLGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISEMEMMK 445
           +L LGKPLGEGCFGQVV+AEA+G+DKDKP     VAVKMLK DATEKDLSDL+SEMEMMK
Sbjct: 481 KLTLGKPLGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLKDDATEKDLSDLVSEMEMMK 540

Query: 446 MIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLQARRPPGLEYCYNPSHNPEEQLS 505
           MIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYL+ARRPPG+EY Y+ +  PEEQ++
Sbjct: 541 MIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGMEYSYDINRVPEEQMT 600

Query: 506 SKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHHIDYYKK 565
            KDLVSC YQ+ARGMEYLAS+KCIHRDLAARNVLVTE+NVMKIADFGLARDI++IDYYKK
Sbjct: 601 FKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDINNIDYYKK 660

Query: 566 TTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVEELFKLLKEG 625
           TTNGRLPVKWMAPEALFDR+YTHQSDVWSFGVL+WEIFTLGGSPYPG+PVEELFKLLKEG
Sbjct: 661 TTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEELFKLLKEG 720

Query: 626 HRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRIVALTSNQ 673
           HRMDKP+NCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRI+ LT+N+
Sbjct: 721 HRMDKPANCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRILTLTTNE 768



 Score = 51.6 bits (122), Expect = 3e-06
 Identities = 63/303 (20%), Positives = 106/303 (34%), Gaps = 75/303 (24%)

Query: 1   MWSWKCLLFWAVLVTATLCTARPSPTLPEQDALPSSEDDDDDDDSSSEEKETDNTKPNPV 60
           M SW   +   V+  ATL  ARPS +L E   L   E                     P 
Sbjct: 1   MVSWGRFICLVVVTMATLSLARPSFSLVEDTTLEPEE---------------------PP 39

Query: 61  APYWTSPEKMEKKLHAVPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPDHR---IGGYKV 117
             Y  S    + +++     ++++ +C         + W K+G    P++R   IG Y  
Sbjct: 40  TKYQIS----QPEVYVAAPGESLEVRCLLKDA--AVISWTKDGVHLGPNNRTVLIGEY-- 91

Query: 118 RYATWSIIMDSVVPSDKGNYTCIVENEYGSINHTYQLDVVE------------------- 158
                 + +    P D G Y C       S    + ++V +                   
Sbjct: 92  ------LQIKGATPRDSGLYACTASRTVDSETWYFMVNVTDAISSGDDEDDTDGAEDFVS 145

Query: 159 ------RSPHRPILQAGLPANKTVALGSNVEFMCKVYSDPQPHIQWLKHIEVNGSKIGPD 212
                 R+P+    +        V   + V+F C    +P P ++WLK    NG +    
Sbjct: 146 ENSNNKRAPYWTNTEKMEKRLHAVPAANTVKFRCPAGGNPMPTMRWLK----NGKE---- 197

Query: 213 NLPYVQILKTAGVNTTDKEMEVLHLRNVSFEDAGEYTCLAGNSIGLSHHSAWLTVLEALE 272
              + Q  +  G    ++   ++ + +V   D G YTC+  N  G  +H+  L V+E   
Sbjct: 198 ---FKQEHRIGGYKVRNQHWSLI-MESVVPSDKGNYTCVVENEYGSINHTYHLDVVERSP 253

Query: 273 ERP 275
            RP
Sbjct: 254 HRP 256


>gi|4503711 fibroblast growth factor receptor 3 isoform 1 precursor
           [Homo sapiens]
          Length = 806

 Score =  986 bits (2549), Expect = 0.0
 Identities = 483/682 (70%), Positives = 566/682 (82%), Gaps = 13/682 (1%)

Query: 34  PSSEDDDDDDDSSSEEKETDNTKPNPVAPYWTSPEKMEKKLHAVPAAKTVKFKCPSSGTP 93
           PSS DD+D +D      E ++T  +  APYWT PE+M+KKL AVPAA TV+F+CP++G P
Sbjct: 129 PSSGDDEDGED------EAEDTGVDTGAPYWTRPERMDKKLLAVPAANTVRFRCPAAGNP 182

Query: 94  NPTLRWLKNGKEFKPDHRIGGYKVRYATWSIIMDSVVPSDKGNYTCIVENEYGSINHTYQ 153
            P++ WLKNG+EF+ +HRIGG K+R+  WS++M+SVVPSD+GNYTC+VEN++GSI  TY 
Sbjct: 183 TPSISWLKNGREFRGEHRIGGIKLRHQQWSLVMESVVPSDRGNYTCVVENKFGSIRQTYT 242

Query: 154 LDVVERSPHRPILQAGLPANKTVALGSNVEFMCKVYSDPQPHIQWLKHIEVNGSKIGPDN 213
           LDV+ERSPHRPILQAGLPAN+T  LGS+VEF CKVYSD QPHIQWLKH+EVNGSK+GPD 
Sbjct: 243 LDVLERSPHRPILQAGLPANQTAVLGSDVEFHCKVYSDAQPHIQWLKHVEVNGSKVGPDG 302

Query: 214 LPYVQILKTAGVNTTDKEMEVLHLRNVSFEDAGEYTCLAGNSIGLSHHSAWLTVLEALEE 273
            PYV +LKTAG NTTDKE+EVL L NV+FEDAGEYTCLAGNSIG SHHSAWL VL A EE
Sbjct: 303 TPYVTVLKTAGANTTDKELEVLSLHNVTFEDAGEYTCLAGNSIGFSHHSAWLVVLPAEEE 362

Query: 274 R-PAVMTSPLYLEIIIYCTGAFLISCMVGSVIVYKMKSGTKKSDFHSQMAVHKLAKSIPL 332
              A     +Y  I+ Y  G FL   +V +V + +++S  KK        VHK+++  PL
Sbjct: 363 LVEADEAGSVYAGILSYGVGFFLFILVVAAVTLCRLRSPPKKG--LGSPTVHKISR-FPL 419

Query: 333 RRQVTVSADSSASMNSGVLLVRPSRLSSSGTPMLAGVSEYELPEDPRWELPRDRLVLGKP 392
           +RQV  S +S+ASM+S   LVR +RLSS   P LA VSE ELP DP+WEL R RL LGKP
Sbjct: 420 KRQV--SLESNASMSSNTPLVRIARLSSGEGPTLANVSELELPADPKWELSRARLTLGKP 477

Query: 393 LGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKN 452
           LGEGCFGQVV+AEAIG+DKD+  +   VAVKMLK DAT+KDLSDL+SEMEMMKMIGKHKN
Sbjct: 478 LGEGCFGQVVMAEAIGIDKDRAAKPVTVAVKMLKDDATDKDLSDLVSEMEMMKMIGKHKN 537

Query: 453 IINLLGACTQDGPLYVIVEYASKGNLREYLQARRPPGLEYCYNPSHNPEEQLSSKDLVSC 512
           IINLLGACTQ GPLYV+VEYA+KGNLRE+L+ARRPPGL+Y ++    PEEQL+ KDLVSC
Sbjct: 538 IINLLGACTQGGPLYVLVEYAAKGNLREFLRARRPPGLDYSFDTCKPPEEQLTFKDLVSC 597

Query: 513 AYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHHIDYYKKTTNGRLP 572
           AYQVARGMEYLAS+KCIHRDLAARNVLVTEDNVMKIADFGLARD+H++DYYKKTTNGRLP
Sbjct: 598 AYQVARGMEYLASQKCIHRDLAARNVLVTEDNVMKIADFGLARDVHNLDYYKKTTNGRLP 657

Query: 573 VKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVEELFKLLKEGHRMDKPS 632
           VKWMAPEALFDR+YTHQSDVWSFGVLLWEIFTLGGSPYPG+PVEELFKLLKEGHRMDKP+
Sbjct: 658 VKWMAPEALFDRVYTHQSDVWSFGVLLWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPA 717

Query: 633 NCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRIVALTSNQEYLDLSMPLDQYSPSFPDT 692
           NCT++LYM+MR+CWHA PSQRPTFKQLVEDLDR++ +TS  EYLDLS P +QYSP   DT
Sbjct: 718 NCTHDLYMIMRECWHAAPSQRPTFKQLVEDLDRVLTVTSTDEYLDLSAPFEQYSPGGQDT 777

Query: 693 RSSTCSSGEDSVFSHEPLPEEP 714
            SS+ SSG+DSVF+H+ LP  P
Sbjct: 778 PSSS-SSGDDSVFAHDLLPPAP 798


>gi|254028242 fibroblast growth factor receptor 3 isoform 3
           precursor [Homo sapiens]
          Length = 808

 Score =  926 bits (2392), Expect = 0.0
 Identities = 460/685 (67%), Positives = 550/685 (80%), Gaps = 17/685 (2%)

Query: 34  PSSEDDDDDDDSSSEEKETDNTKPNPVAPYWTSPEKMEKKLHAVPAAKTVKFKCPSSGTP 93
           PSS DD+D +D      E ++T  +  APYWT PE+M+KKL AVPAA TV+F+CP++G P
Sbjct: 129 PSSGDDEDGED------EAEDTGVDTGAPYWTRPERMDKKLLAVPAANTVRFRCPAAGNP 182

Query: 94  NPTLRWLKNGKEFKPDHRIGGYKVRYATWSIIMDSVVPSDKGNYTCIVENEYGSINHTYQ 153
            P++ WLKNG+EF+ +HRIGG K+R+  WS++M+SVVPSD+GNYTC+VEN++GSI  TY 
Sbjct: 183 TPSISWLKNGREFRGEHRIGGIKLRHQQWSLVMESVVPSDRGNYTCVVENKFGSIRQTYT 242

Query: 154 LDVVERSPHRPILQAGLPANKTVALGSNVEFMCKVYSDPQPHIQWLKHIEVNGSKIGPDN 213
           LDV+ERSPHRPILQAGLPAN+T  LGS+VEF CKVYSD QPHIQWLKH+EVNGSK+GPD 
Sbjct: 243 LDVLERSPHRPILQAGLPANQTAVLGSDVEFHCKVYSDAQPHIQWLKHVEVNGSKVGPDG 302

Query: 214 LPYVQILKTAGVNTTDKEMEVLHLRNVSFEDAGEYTCLAGNSIGLSHHSAWLTVL--EAL 271
            PYV +LK+    + + ++  L L NVS  D GEY C A N IG++  + WL+V    A 
Sbjct: 303 TPYVTVLKSWISESVEADVR-LRLANVSERDGGEYLCRATNFIGVAEKAFWLSVHGPRAA 361

Query: 272 EER--PAVMTSPLYLEIIIYCTGAFLISCMVGSVIVYKMKSGTKKSDFHSQMAVHKLAKS 329
           EE    A     +Y  I+ Y  G FL   +V +V + +++S  KK        VHK+++ 
Sbjct: 362 EEELVEADEAGSVYAGILSYGVGFFLFILVVAAVTLCRLRSPPKKG--LGSPTVHKISR- 418

Query: 330 IPLRRQVTVSADSSASMNSGVLLVRPSRLSSSGTPMLAGVSEYELPEDPRWELPRDRLVL 389
            PL+RQV  S +S+ASM+S   LVR +RLSS   P LA VSE ELP DP+WEL R RL L
Sbjct: 419 FPLKRQV--SLESNASMSSNTPLVRIARLSSGEGPTLANVSELELPADPKWELSRARLTL 476

Query: 390 GKPLGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISEMEMMKMIGK 449
           GKPLGEGCFGQVV+AEAIG+DKD+  +   VAVKMLK DAT+KDLSDL+SEMEMMKMIGK
Sbjct: 477 GKPLGEGCFGQVVMAEAIGIDKDRAAKPVTVAVKMLKDDATDKDLSDLVSEMEMMKMIGK 536

Query: 450 HKNIINLLGACTQDGPLYVIVEYASKGNLREYLQARRPPGLEYCYNPSHNPEEQLSSKDL 509
           HKNIINLLGACTQ GPLYV+VEYA+KGNLRE+L+ARRPPGL+Y ++    PEEQL+ KDL
Sbjct: 537 HKNIINLLGACTQGGPLYVLVEYAAKGNLREFLRARRPPGLDYSFDTCKPPEEQLTFKDL 596

Query: 510 VSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHHIDYYKKTTNG 569
           VSCAYQVARGMEYLAS+KCIHRDLAARNVLVTEDNVMKIADFGLARD+H++DYYKKTTNG
Sbjct: 597 VSCAYQVARGMEYLASQKCIHRDLAARNVLVTEDNVMKIADFGLARDVHNLDYYKKTTNG 656

Query: 570 RLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVEELFKLLKEGHRMD 629
           RLPVKWMAPEALFDR+YTHQSDVWSFGVLLWEIFTLGGSPYPG+PVEELFKLLKEGHRMD
Sbjct: 657 RLPVKWMAPEALFDRVYTHQSDVWSFGVLLWEIFTLGGSPYPGIPVEELFKLLKEGHRMD 716

Query: 630 KPSNCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRIVALTSNQEYLDLSMPLDQYSPSF 689
           KP+NCT++LYM+MR+CWHA PSQRPTFKQLVEDLDR++ +TS  EYLDLS P +QYSP  
Sbjct: 717 KPANCTHDLYMIMRECWHAAPSQRPTFKQLVEDLDRVLTVTSTDEYLDLSAPFEQYSPGG 776

Query: 690 PDTRSSTCSSGEDSVFSHEPLPEEP 714
            DT SS+ SSG+DSVF+H+ LP  P
Sbjct: 777 QDTPSSS-SSGDDSVFAHDLLPPAP 800


>gi|47524175 fibroblast growth factor receptor 4 isoform 1 precursor
           [Homo sapiens]
          Length = 802

 Score =  868 bits (2242), Expect = 0.0
 Identities = 445/705 (63%), Positives = 541/705 (76%), Gaps = 27/705 (3%)

Query: 18  LCTARPSP------TLPEQDALPSSEDDDDDDDSSSEEKETDNTKPNPVAPYWTSPEKME 71
           LC AR S       TL   D+L SS  +DD+D  S  +    ++ P   APYWT P++ME
Sbjct: 100 LCLARGSMIVLQNLTLITGDSLTSS--NDDEDPKSHRDPSNRHSYPQQ-APYWTHPQRME 156

Query: 72  KKLHAVPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPDHRIGGYKVRYATWSIIMDSVVP 131
           KKLHAVPA  TVKF+CP++G P PT+RWLK+G+ F  ++RIGG ++R+  WS++M+SVVP
Sbjct: 157 KKLHAVPAGNTVKFRCPAAGNPTPTIRWLKDGQAFHGENRIGGIRLRHQHWSLVMESVVP 216

Query: 132 SDKGNYTCIVENEYGSINHTYQLDVVERSPHRPILQAGLPANKTVALGSNVEFMCKVYSD 191
           SD+G YTC+VEN  GSI + Y LDV+ERSPHRPILQAGLPAN T  +GS+VE +CKVYSD
Sbjct: 217 SDRGTYTCLVENAVGSIRYNYLLDVLERSPHRPILQAGLPANTTAVVGSDVELLCKVYSD 276

Query: 192 PQPHIQWLKHIEVNGSKIGPDNLPYVQILKTAGVNTTDKEMEVLHLRNVSFEDAGEYTCL 251
            QPHIQWLKHI +NGS  G D  PYVQ+LKTA +N++  E+EVL+LRNVS EDAGEYTCL
Sbjct: 277 AQPHIQWLKHIVINGSSFGADGFPYVQVLKTADINSS--EVEVLYLRNVSAEDAGEYTCL 334

Query: 252 AGNSIGLSHHSAWLTVLEALEERP---AVMTSPLYLEIIIYCTGAFLISCMVGSVIVYKM 308
           AGNSIGLS+ SAWLTVL   EE P   A      Y +II+Y +G+  ++ ++    +Y+ 
Sbjct: 335 AGNSIGLSYQSAWLTVLP--EEDPTWTAAAPEARYTDIILYASGSLALAVLLLLAGLYR- 391

Query: 309 KSGTKKSDFHSQ--MAVHKLAKSIPLRRQVTVSADSSASMNSGVLLVRPSRLSSSGTPML 366
             G      H +    V KL++  PL RQ ++ + SS   +S   LVR  RLSSSG  +L
Sbjct: 392 --GQALHGRHPRPPATVQKLSR-FPLARQFSLESGSSGKSSSS--LVRGVRLSSSGPALL 446

Query: 367 AGVSEYELPEDPRWELPRDRLVLGKPLGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLK 426
           AG+   +LP DP WE PRDRLVLGKPLGEGCFGQVV AEA G+D  +P++ + VAVKMLK
Sbjct: 447 AGLVSLDLPLDPLWEFPRDRLVLGKPLGEGCFGQVVRAEAFGMDPARPDQASTVAVKMLK 506

Query: 427 SDATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLQARR 486
            +A++KDL+DL+SEME+MK+IG+HKNIINLLG CTQ+GPLYVIVE A+KGNLRE+L+ARR
Sbjct: 507 DNASDKDLADLVSEMEVMKLIGRHKNIINLLGVCTQEGPLYVIVECAAKGNLREFLRARR 566

Query: 487 PPGLEYCYNPSHNPEEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVM 546
           PPG +   +   + E  LS   LVSCAYQVARGM+YL S+KCIHRDLAARNVLVTEDNVM
Sbjct: 567 PPGPDLSPDGPRSSEGPLSFPVLVSCAYQVARGMQYLESRKCIHRDLAARNVLVTEDNVM 626

Query: 547 KIADFGLARDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLG 606
           KIADFGLAR +HHIDYYKKT+NGRLPVKWMAPEALFDR+YTHQSDVWSFG+LLWEIFTLG
Sbjct: 627 KIADFGLARGVHHIDYYKKTSNGRLPVKWMAPEALFDRVYTHQSDVWSFGILLWEIFTLG 686

Query: 607 GSPYPGVPVEELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRI 666
           GSPYPG+PVEELF LL+EGHRMD+P +C  ELY +MR+CWHA PSQRPTFKQLVE LD++
Sbjct: 687 GSPYPGIPVEELFSLLREGHRMDRPPHCPPELYGLMRECWHAAPSQRPTFKQLVEALDKV 746

Query: 667 VALTSNQEYLDLSMPLDQYSPSFPDTRSSTCSSGEDSVFSHEPLP 711
           + L  ++EYLDL +    YSPS  D  SSTCSS  DSVFSH+PLP
Sbjct: 747 L-LAVSEEYLDLRLTFGPYSPSGGDA-SSTCSS-SDSVFSHDPLP 788


>gi|47524173 fibroblast growth factor receptor 4 isoform 1 precursor
           [Homo sapiens]
          Length = 802

 Score =  868 bits (2242), Expect = 0.0
 Identities = 445/705 (63%), Positives = 541/705 (76%), Gaps = 27/705 (3%)

Query: 18  LCTARPSP------TLPEQDALPSSEDDDDDDDSSSEEKETDNTKPNPVAPYWTSPEKME 71
           LC AR S       TL   D+L SS  +DD+D  S  +    ++ P   APYWT P++ME
Sbjct: 100 LCLARGSMIVLQNLTLITGDSLTSS--NDDEDPKSHRDPSNRHSYPQQ-APYWTHPQRME 156

Query: 72  KKLHAVPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPDHRIGGYKVRYATWSIIMDSVVP 131
           KKLHAVPA  TVKF+CP++G P PT+RWLK+G+ F  ++RIGG ++R+  WS++M+SVVP
Sbjct: 157 KKLHAVPAGNTVKFRCPAAGNPTPTIRWLKDGQAFHGENRIGGIRLRHQHWSLVMESVVP 216

Query: 132 SDKGNYTCIVENEYGSINHTYQLDVVERSPHRPILQAGLPANKTVALGSNVEFMCKVYSD 191
           SD+G YTC+VEN  GSI + Y LDV+ERSPHRPILQAGLPAN T  +GS+VE +CKVYSD
Sbjct: 217 SDRGTYTCLVENAVGSIRYNYLLDVLERSPHRPILQAGLPANTTAVVGSDVELLCKVYSD 276

Query: 192 PQPHIQWLKHIEVNGSKIGPDNLPYVQILKTAGVNTTDKEMEVLHLRNVSFEDAGEYTCL 251
            QPHIQWLKHI +NGS  G D  PYVQ+LKTA +N++  E+EVL+LRNVS EDAGEYTCL
Sbjct: 277 AQPHIQWLKHIVINGSSFGADGFPYVQVLKTADINSS--EVEVLYLRNVSAEDAGEYTCL 334

Query: 252 AGNSIGLSHHSAWLTVLEALEERP---AVMTSPLYLEIIIYCTGAFLISCMVGSVIVYKM 308
           AGNSIGLS+ SAWLTVL   EE P   A      Y +II+Y +G+  ++ ++    +Y+ 
Sbjct: 335 AGNSIGLSYQSAWLTVLP--EEDPTWTAAAPEARYTDIILYASGSLALAVLLLLAGLYR- 391

Query: 309 KSGTKKSDFHSQ--MAVHKLAKSIPLRRQVTVSADSSASMNSGVLLVRPSRLSSSGTPML 366
             G      H +    V KL++  PL RQ ++ + SS   +S   LVR  RLSSSG  +L
Sbjct: 392 --GQALHGRHPRPPATVQKLSR-FPLARQFSLESGSSGKSSSS--LVRGVRLSSSGPALL 446

Query: 367 AGVSEYELPEDPRWELPRDRLVLGKPLGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLK 426
           AG+   +LP DP WE PRDRLVLGKPLGEGCFGQVV AEA G+D  +P++ + VAVKMLK
Sbjct: 447 AGLVSLDLPLDPLWEFPRDRLVLGKPLGEGCFGQVVRAEAFGMDPARPDQASTVAVKMLK 506

Query: 427 SDATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLQARR 486
            +A++KDL+DL+SEME+MK+IG+HKNIINLLG CTQ+GPLYVIVE A+KGNLRE+L+ARR
Sbjct: 507 DNASDKDLADLVSEMEVMKLIGRHKNIINLLGVCTQEGPLYVIVECAAKGNLREFLRARR 566

Query: 487 PPGLEYCYNPSHNPEEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVM 546
           PPG +   +   + E  LS   LVSCAYQVARGM+YL S+KCIHRDLAARNVLVTEDNVM
Sbjct: 567 PPGPDLSPDGPRSSEGPLSFPVLVSCAYQVARGMQYLESRKCIHRDLAARNVLVTEDNVM 626

Query: 547 KIADFGLARDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLG 606
           KIADFGLAR +HHIDYYKKT+NGRLPVKWMAPEALFDR+YTHQSDVWSFG+LLWEIFTLG
Sbjct: 627 KIADFGLARGVHHIDYYKKTSNGRLPVKWMAPEALFDRVYTHQSDVWSFGILLWEIFTLG 686

Query: 607 GSPYPGVPVEELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRI 666
           GSPYPG+PVEELF LL+EGHRMD+P +C  ELY +MR+CWHA PSQRPTFKQLVE LD++
Sbjct: 687 GSPYPGIPVEELFSLLREGHRMDRPPHCPPELYGLMRECWHAAPSQRPTFKQLVEALDKV 746

Query: 667 VALTSNQEYLDLSMPLDQYSPSFPDTRSSTCSSGEDSVFSHEPLP 711
           + L  ++EYLDL +    YSPS  D  SSTCSS  DSVFSH+PLP
Sbjct: 747 L-LAVSEEYLDLRLTFGPYSPSGGDA-SSTCSS-SDSVFSHDPLP 788


>gi|47524177 fibroblast growth factor receptor 4 isoform 2 precursor
           [Homo sapiens]
          Length = 762

 Score =  841 bits (2173), Expect = 0.0
 Identities = 432/700 (61%), Positives = 516/700 (73%), Gaps = 57/700 (8%)

Query: 18  LCTARPSP------TLPEQDALPSSEDDDDDDDSSSEEKETDNTKPNPVAPYWTSPEKME 71
           LC AR S       TL   D+L SS  +DD+D  S  +    ++ P   APYWT P++ME
Sbjct: 100 LCLARGSMIVLQNLTLITGDSLTSS--NDDEDPKSHRDPSNRHSYPQQ-APYWTHPQRME 156

Query: 72  KKLHAVPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPDHRIGGYKVRYATWSIIMDSVVP 131
           KKLHAVPA  TVKF+CP++G P PT+RWLK+G+ F  ++RIGG ++R+  WS++M+SVVP
Sbjct: 157 KKLHAVPAGNTVKFRCPAAGNPTPTIRWLKDGQAFHGENRIGGIRLRHQHWSLVMESVVP 216

Query: 132 SDKGNYTCIVENEYGSINHTYQLDVVERSPHRPILQAGLPANKTVALGSNVEFMCKVYSD 191
           SD+G YTC+VEN  GSI + Y LDV+ERSPHRPILQAGLPAN T  +GS+VE +CKVYSD
Sbjct: 217 SDRGTYTCLVENAVGSIRYNYLLDVLERSPHRPILQAGLPANTTAVVGSDVELLCKVYSD 276

Query: 192 PQPHIQWLKHIEVNGSKIGPDNLPYVQILKTAGVNTTDKEMEVLHLRNVSFEDAGEYTCL 251
            QPHIQWLKHI +NGS  G D  PYVQ+LKTA +N++  E+EVL+LRNVS EDAGEYTCL
Sbjct: 277 AQPHIQWLKHIVINGSSFGADGFPYVQVLKTADINSS--EVEVLYLRNVSAEDAGEYTCL 334

Query: 252 AGNSIGLSHHSAWLTVLEALEERPAVMTSPLYLEIIIYCTGAFLISCMVGSVIVYKMKSG 311
           AGNSIGLS+ SAWLTVL      P +    L                           +G
Sbjct: 335 AGNSIGLSYQSAWLTVLPGTGRIPHLTCDSL-------------------------TPAG 369

Query: 312 TKKSDFHSQMAVHKLAKSIPLRRQVTVSADSSASMNSGVLLVRPSRLSSSGTPMLAGVSE 371
             KS                    +  S +S +S  S   LVR  RLSSSG  +LAG+  
Sbjct: 370 RTKSP------------------TLQFSLESGSSGKSSSSLVRGVRLSSSGPALLAGLVS 411

Query: 372 YELPEDPRWELPRDRLVLGKPLGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATE 431
            +LP DP WE PRDRLVLGKPLGEGCFGQVV AEA G+D  +P++ + VAVKMLK +A++
Sbjct: 412 LDLPLDPLWEFPRDRLVLGKPLGEGCFGQVVRAEAFGMDPARPDQASTVAVKMLKDNASD 471

Query: 432 KDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLQARRPPGLE 491
           KDL+DL+SEME+MK+IG+HKNIINLLG CTQ+GPLYVIVE A+KGNLRE+L+ARRPPG +
Sbjct: 472 KDLADLVSEMEVMKLIGRHKNIINLLGVCTQEGPLYVIVECAAKGNLREFLRARRPPGPD 531

Query: 492 YCYNPSHNPEEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADF 551
              +   + E  LS   LVSCAYQVARGM+YL S+KCIHRDLAARNVLVTEDNVMKIADF
Sbjct: 532 LSPDGPRSSEGPLSFPVLVSCAYQVARGMQYLESRKCIHRDLAARNVLVTEDNVMKIADF 591

Query: 552 GLARDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYP 611
           GLAR +HHIDYYKKT+NGRLPVKWMAPEALFDR+YTHQSDVWSFG+LLWEIFTLGGSPYP
Sbjct: 592 GLARGVHHIDYYKKTSNGRLPVKWMAPEALFDRVYTHQSDVWSFGILLWEIFTLGGSPYP 651

Query: 612 GVPVEELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRIVALTS 671
           G+PVEELF LL+EGHRMD+P +C  ELY +MR+CWHA PSQRPTFKQLVE LD+++ L  
Sbjct: 652 GIPVEELFSLLREGHRMDRPPHCPPELYGLMRECWHAAPSQRPTFKQLVEALDKVL-LAV 710

Query: 672 NQEYLDLSMPLDQYSPSFPDTRSSTCSSGEDSVFSHEPLP 711
           ++EYLDL +    YSPS  D  SSTCSS  DSVFSH+PLP
Sbjct: 711 SEEYLDLRLTFGPYSPSGGDA-SSTCSS-SDSVFSHDPLP 748



 Score = 53.1 bits (126), Expect = 9e-07
 Identities = 56/234 (23%), Positives = 89/234 (38%), Gaps = 45/234 (19%)

Query: 66  SPEKMEKKLHAVPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPDHRIGGYKVRYATWSII 125
           S E+ E++L  V   + V+  C   G       W K G    P  R+ G++ R     + 
Sbjct: 37  SLEQQEQEL-TVALGQPVRLCC---GRAERGGHWYKEGSRLAPAGRVRGWRGR-----LE 87

Query: 126 MDSVVPSDKGNYTCIVENEYGSINH---------TYQLDVVERSPHR-PILQAGLPANK- 174
           + S +P D G Y C+       + +         T   D  +   HR P  +   P    
Sbjct: 88  IASFLPEDAGRYLCLARGSMIVLQNLTLITGDSLTSSNDDEDPKSHRDPSNRHSYPQQAP 147

Query: 175 -------------TVALGSNVEFMCKVYSDPQPHIQWLKHIEVNGSKIGPDNLPYVQILK 221
                         V  G+ V+F C    +P P I+WLK    +G     +N       +
Sbjct: 148 YWTHPQRMEKKLHAVPAGNTVKFRCPAAGNPTPTIRWLK----DGQAFHGEN-------R 196

Query: 222 TAGVNTTDKEMEVLHLRNVSFEDAGEYTCLAGNSIGLSHHSAWLTVLEALEERP 275
             G+    +   ++ + +V   D G YTCL  N++G   ++  L VLE    RP
Sbjct: 197 IGGIRLRHQHWSLV-MESVVPSDRGTYTCLVENAVGSIRYNYLLDVLERSPHRP 249


>gi|222144233 fibroblast growth factor receptor 2 isoform 4
           precursor [Homo sapiens]
          Length = 709

 Score =  788 bits (2036), Expect = 0.0
 Identities = 428/759 (56%), Positives = 515/759 (67%), Gaps = 81/759 (10%)

Query: 1   MWSWKCLLFWAVLVTATLCTARPSPTLPEQDALPSSEDDDDDDDSSSEEKETDNTKPNPV 60
           M SW   +   V+  ATL  ARPS +L E   L   E                     P 
Sbjct: 1   MVSWGRFICLVVVTMATLSLARPSFSLVEDTTLEPEE---------------------PP 39

Query: 61  APYWTSPEKMEKKLHAVPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPDHR---IGGYKV 117
             Y  S    + +++     ++++ +C         + W K+G    P++R   IG Y  
Sbjct: 40  TKYQIS----QPEVYVAAPGESLEVRCLLKDAA--VISWTKDGVHLGPNNRTVLIGEY-- 91

Query: 118 RYATWSIIMDSVVPSDKGNYTCIVENEYGSINHTYQLDVVE------------------- 158
                 + +    P D G Y C       S    + ++V +                   
Sbjct: 92  ------LQIKGATPRDSGLYACTASRTVDSETWYFMVNVTDAISSGDDEDDTDGAEDFVS 145

Query: 159 ------RSPHRPILQAGLPANKTVALGSNVEFMCKVYSDPQPHIQWLKHIEVNGSKIGPD 212
                 R+P+    +        V   + V+F C    +P P ++WLK    NG +   +
Sbjct: 146 ENSNNKRAPYWTNTEKMEKRLHAVPAANTVKFRCPAGGNPMPTMRWLK----NGKEFKQE 201

Query: 213 NLPYVQILKTAGVNTTDKEMEVLHLRNVSFEDAGEYTCLAGNSIGLSHHSAWLTVLEALE 272
           +       +  G    ++   ++ + +V   D G YTC+  N  G  +H+  L V+    
Sbjct: 202 H-------RIGGYKVRNQHWSLI-MESVVPSDKGNYTCVVENEYGSINHTYHLDVVAPGR 253

Query: 273 ERPAVMTSPLYLEIIIYCTGAFLISCMVGSVIVYKMKSGTKKSDFHSQMAVHKLAKSIPL 332
           E+  +  SP YLEI IYC G FLI+CMV +VI+ +MK+ TKK DF SQ AVHKL K IPL
Sbjct: 254 EKE-ITASPDYLEIAIYCIGVFLIACMVVTVILCRMKNTTKKPDFSSQPAVHKLTKRIPL 312

Query: 333 RRQVTVSADSSASMNSGVLLVR-PSRLSSSG-TPMLAGVSEYELPEDPRWELPRDRLVLG 390
           RRQVTVSA+SS+SMNS   LVR  +RLSS+  TPMLAGVSEYELPEDP+WE PRD+L LG
Sbjct: 313 RRQVTVSAESSSSMNSNTPLVRITTRLSSTADTPMLAGVSEYELPEDPKWEFPRDKLTLG 372

Query: 391 KPLGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISEMEMMKMIGKH 450
           KPLGEGCFGQVV+AEA+G+DKDKP     VAVKMLK DATEKDLSDL+SEMEMMKMIGKH
Sbjct: 373 KPLGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLKDDATEKDLSDLVSEMEMMKMIGKH 432

Query: 451 KNIINLLGACTQDGPLYVIVEYASKGNLREYLQARRPPGLEYCYNPSHNPEEQLSSKDLV 510
           KNIINLLGACTQDGPLYVIVEYASKGNLREYL+ARRPPG+EY Y+ +  PEEQ++ KDLV
Sbjct: 433 KNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGMEYSYDINRVPEEQMTFKDLV 492

Query: 511 SCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHHIDYYKKTTNGR 570
           SC YQ+ARGMEYLAS+KCIHRDLAARNVLVTE+NVMKIADFGLARDI++IDYYKKTTNGR
Sbjct: 493 SCTYQLARGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDINNIDYYKKTTNGR 552

Query: 571 LPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVEELFKLLKEGHRMDK 630
           LPVKWMAPEALFDR+YTHQSDVWSFGVL+WEIFTLGGSPYPG+PVEELFKLLKEGHRMDK
Sbjct: 553 LPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEELFKLLKEGHRMDK 612

Query: 631 PSNCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRIVALTSNQEYLDLSMPLDQYSPSFP 690
           P+NCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRI+ LT+N+EYLDLS PL+QYSPS+P
Sbjct: 613 PANCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRILTLTTNEEYLDLSQPLEQYSPSYP 672

Query: 691 DTRSSTCSSGEDSVFSHEPLPEEPCLPRHPAQLANGGLK 729
           DTRSS CSSG+DSVFS +P+P EPCLP++P    NG +K
Sbjct: 673 DTRSS-CSSGDDSVFSPDPMPYEPCLPQYPH--INGSVK 708


>gi|222144239 fibroblast growth factor receptor 2 isoform 7
           precursor [Homo sapiens]
          Length = 705

 Score =  709 bits (1830), Expect = 0.0
 Identities = 399/766 (52%), Positives = 488/766 (63%), Gaps = 99/766 (12%)

Query: 1   MWSWKCLLFWAVLVTATLCTARPSPTLPEQDALPSSEDDDDDDDSSSEEKETDNTKPNPV 60
           M SW   +   V+  ATL  ARPS +L E   L   E                     P 
Sbjct: 1   MVSWGRFICLVVVTMATLSLARPSFSLVEDTTLEPEE---------------------PP 39

Query: 61  APYWTSPEKMEKKLHAVPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPDHR---IGGYKV 117
             Y  S    + +++     ++++ +C         + W K+G    P++R   IG Y  
Sbjct: 40  TKYQIS----QPEVYVAAPGESLEVRCLLKDAA--VISWTKDGVHLGPNNRTVLIGEY-- 91

Query: 118 RYATWSIIMDSVVPSDKGNYTCIVENEYGSINHTYQLDVVE------------------- 158
                 + +    P D G Y C       S    + ++V +                   
Sbjct: 92  ------LQIKGATPRDSGLYACTASRTVDSETWYFMVNVTDAISSGDDEDDTDGAEDFVS 145

Query: 159 ------RSPHRPILQAGLPANKTVALGSNVEFMCKVYSDPQPHIQWLKHIEVNGSKIGPD 212
                 R+P+    +        V   + V+F C    +P P ++WLK    NG +   +
Sbjct: 146 ENSNNKRAPYWTNTEKMEKRLHAVPAANTVKFRCPAGGNPMPTMRWLK----NGKEFKQE 201

Query: 213 NLPYVQILKTAGVNTTDKEMEVLHLRNVSFEDAGEYTCLAGNSIGLSHHSAWLTVLEALE 272
           +       +  G    ++   ++ + +V   D G YTC+  N  G  +H+  L V+E   
Sbjct: 202 H-------RIGGYKVRNQHWSLI-MESVVPSDKGNYTCVVENEYGSINHTYHLDVVERSP 253

Query: 273 ERPAVMTSPLYLEIIIYCTGAFLISCMVGSV-------IVYKMKSGTKKSDFHSQMAVHK 325
            RP ++ + L         G     C V S        I +  K+G+K            
Sbjct: 254 HRP-ILQAGLPANASTVVGGDVEFVCKVYSDAQPHIQWIKHVEKNGSKYGP--------- 303

Query: 326 LAKSIPLRRQVTVSADSSASMNSGVLLVR-PSRLSSSG-TPMLAGVSEYELPEDPRWELP 383
               +P  + + VSA+SS+SMNS   LVR  +RLSS+  TPMLAGVSEYELPEDP+WE P
Sbjct: 304 --DGLPYLKVLKVSAESSSSMNSNTPLVRITTRLSSTADTPMLAGVSEYELPEDPKWEFP 361

Query: 384 RDRLVLGKPLGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISEMEM 443
           RD+L LGKPLGEGCFGQVV+AEA+G+DKDKP     VAVKMLK DATEKDLSDL+SEMEM
Sbjct: 362 RDKLTLGKPLGEGCFGQVVMAEAVGIDKDKPKEAVTVAVKMLKDDATEKDLSDLVSEMEM 421

Query: 444 MKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLQARRPPGLEYCYNPSHNPEEQ 503
           MKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYL+ARRPPG+EY Y+ +  PEEQ
Sbjct: 422 MKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGMEYSYDINRVPEEQ 481

Query: 504 LSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHHIDYY 563
           ++ KDLVSC YQ+ARGMEYLAS+KCIHRDLAARNVLVTE+NVMKIADFGLARDI++IDYY
Sbjct: 482 MTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDINNIDYY 541

Query: 564 KKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVEELFKLLK 623
           KKTTNGRLPVKWMAPEALFDR+YTHQSDVWSFGVL+WEIFTLGGSPYPG+PVEELFKLLK
Sbjct: 542 KKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEELFKLLK 601

Query: 624 EGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRIVALTSNQEYLDLSMPLD 683
           EGHRMDKP+NCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRI+ LT+N+EYLDLS PL+
Sbjct: 602 EGHRMDKPANCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRILTLTTNEEYLDLSQPLE 661

Query: 684 QYSPSFPDTRSSTCSSGEDSVFSHEPLPEEPCLPRHPAQLANGGLK 729
           QYSPS+PDTRSS CSSG+DSVFS +P+P EPCLP++P    NG +K
Sbjct: 662 QYSPSYPDTRSS-CSSGDDSVFSPDPMPYEPCLPQYPH--INGSVK 704


>gi|13112048 fibroblast growth factor receptor 3 isoform 2 precursor
           [Homo sapiens]
          Length = 694

 Score =  634 bits (1636), Expect = 0.0
 Identities = 333/547 (60%), Positives = 395/547 (72%), Gaps = 34/547 (6%)

Query: 176 VALGSNVEFMCKVYSDPQPHIQWLKHIEVNGSKIGPDNLPYVQILKTAGVNTTDKEMEVL 235
           V   + V F C    +P P I WLK    NG +   ++       +  G+    ++  ++
Sbjct: 166 VPAANTVRFRCPAAGNPTPSISWLK----NGREFRGEH-------RIGGIKLRHQQWSLV 214

Query: 236 HLRNVSFEDAGEYTCLAGNSIGLSHHSAWLTVLEALEERP-------AVMTSPLYLEIII 288
            + +V   D G YTC+  N  G    +  L VLE    RP       A  T+ L  ++  
Sbjct: 215 -MESVVPSDRGNYTCVVENKFGSIRQTYTLDVLERSPHRPILQAGLPANQTAVLGSDVEF 273

Query: 289 YCTGAFLISCMVGSVIVYKMKSGTKKSDFHSQMAVHKLAKS-IPLRRQVTVSADSSASMN 347
           +C              VY       +   H ++   K+     P    + VS +S+ASM+
Sbjct: 274 HCK-------------VYSDAQPHIQWLKHVEVNGSKVGPDGTPYVTVLKVSLESNASMS 320

Query: 348 SGVLLVRPSRLSSSGTPMLAGVSEYELPEDPRWELPRDRLVLGKPLGEGCFGQVVLAEAI 407
           S   LVR +RLSS   P LA VSE ELP DP+WEL R RL LGKPLGEGCFGQVV+AEAI
Sbjct: 321 SNTPLVRIARLSSGEGPTLANVSELELPADPKWELSRARLTLGKPLGEGCFGQVVMAEAI 380

Query: 408 GLDKDKPNRVTKVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLY 467
           G+DKD+  +   VAVKMLK DAT+KDLSDL+SEMEMMKMIGKHKNIINLLGACTQ GPLY
Sbjct: 381 GIDKDRAAKPVTVAVKMLKDDATDKDLSDLVSEMEMMKMIGKHKNIINLLGACTQGGPLY 440

Query: 468 VIVEYASKGNLREYLQARRPPGLEYCYNPSHNPEEQLSSKDLVSCAYQVARGMEYLASKK 527
           V+VEYA+KGNLRE+L+ARRPPGL+Y ++    PEEQL+ KDLVSCAYQVARGMEYLAS+K
Sbjct: 441 VLVEYAAKGNLREFLRARRPPGLDYSFDTCKPPEEQLTFKDLVSCAYQVARGMEYLASQK 500

Query: 528 CIHRDLAARNVLVTEDNVMKIADFGLARDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYT 587
           CIHRDLAARNVLVTEDNVMKIADFGLARD+H++DYYKKTTNGRLPVKWMAPEALFDR+YT
Sbjct: 501 CIHRDLAARNVLVTEDNVMKIADFGLARDVHNLDYYKKTTNGRLPVKWMAPEALFDRVYT 560

Query: 588 HQSDVWSFGVLLWEIFTLGGSPYPGVPVEELFKLLKEGHRMDKPSNCTNELYMMMRDCWH 647
           HQSDVWSFGVLLWEIFTLGGSPYPG+PVEELFKLLKEGHRMDKP+NCT++LYM+MR+CWH
Sbjct: 561 HQSDVWSFGVLLWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTHDLYMIMRECWH 620

Query: 648 AVPSQRPTFKQLVEDLDRIVALTSNQEYLDLSMPLDQYSPSFPDTRSSTCSSGEDSVFSH 707
           A PSQRPTFKQLVEDLDR++ +TS  EYLDLS P +QYSP   DT SS+ SSG+DSVF+H
Sbjct: 621 AAPSQRPTFKQLVEDLDRVLTVTSTDEYLDLSAPFEQYSPGGQDTPSSS-SSGDDSVFAH 679

Query: 708 EPLPEEP 714
           + LP  P
Sbjct: 680 DLLPPAP 686



 Score =  277 bits (709), Expect = 2e-74
 Identities = 124/190 (65%), Positives = 156/190 (82%), Gaps = 6/190 (3%)

Query: 34  PSSEDDDDDDDSSSEEKETDNTKPNPVAPYWTSPEKMEKKLHAVPAAKTVKFKCPSSGTP 93
           PSS DD+D +D      E ++T  +  APYWT PE+M+KKL AVPAA TV+F+CP++G P
Sbjct: 129 PSSGDDEDGED------EAEDTGVDTGAPYWTRPERMDKKLLAVPAANTVRFRCPAAGNP 182

Query: 94  NPTLRWLKNGKEFKPDHRIGGYKVRYATWSIIMDSVVPSDKGNYTCIVENEYGSINHTYQ 153
            P++ WLKNG+EF+ +HRIGG K+R+  WS++M+SVVPSD+GNYTC+VEN++GSI  TY 
Sbjct: 183 TPSISWLKNGREFRGEHRIGGIKLRHQQWSLVMESVVPSDRGNYTCVVENKFGSIRQTYT 242

Query: 154 LDVVERSPHRPILQAGLPANKTVALGSNVEFMCKVYSDPQPHIQWLKHIEVNGSKIGPDN 213
           LDV+ERSPHRPILQAGLPAN+T  LGS+VEF CKVYSD QPHIQWLKH+EVNGSK+GPD 
Sbjct: 243 LDVLERSPHRPILQAGLPANQTAVLGSDVEFHCKVYSDAQPHIQWLKHVEVNGSKVGPDG 302

Query: 214 LPYVQILKTA 223
            PYV +LK +
Sbjct: 303 TPYVTVLKVS 312


>gi|13186241 fibroblast growth factor receptor 1 isoform 6 precursor
           [Homo sapiens]
          Length = 300

 Score =  471 bits (1211), Expect = e-132
 Identities = 221/221 (100%), Positives = 221/221 (100%)

Query: 1   MWSWKCLLFWAVLVTATLCTARPSPTLPEQDALPSSEDDDDDDDSSSEEKETDNTKPNPV 60
           MWSWKCLLFWAVLVTATLCTARPSPTLPEQDALPSSEDDDDDDDSSSEEKETDNTKPNPV
Sbjct: 1   MWSWKCLLFWAVLVTATLCTARPSPTLPEQDALPSSEDDDDDDDSSSEEKETDNTKPNPV 60

Query: 61  APYWTSPEKMEKKLHAVPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPDHRIGGYKVRYA 120
           APYWTSPEKMEKKLHAVPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPDHRIGGYKVRYA
Sbjct: 61  APYWTSPEKMEKKLHAVPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPDHRIGGYKVRYA 120

Query: 121 TWSIIMDSVVPSDKGNYTCIVENEYGSINHTYQLDVVERSPHRPILQAGLPANKTVALGS 180
           TWSIIMDSVVPSDKGNYTCIVENEYGSINHTYQLDVVERSPHRPILQAGLPANKTVALGS
Sbjct: 121 TWSIIMDSVVPSDKGNYTCIVENEYGSINHTYQLDVVERSPHRPILQAGLPANKTVALGS 180

Query: 181 NVEFMCKVYSDPQPHIQWLKHIEVNGSKIGPDNLPYVQILK 221
           NVEFMCKVYSDPQPHIQWLKHIEVNGSKIGPDNLPYVQILK
Sbjct: 181 NVEFMCKVYSDPQPHIQWLKHIEVNGSKIGPDNLPYVQILK 221



 Score = 43.1 bits (100), Expect = 0.001
 Identities = 31/106 (29%), Positives = 46/106 (43%), Gaps = 18/106 (16%)

Query: 170 LPANKTVALGSNVEFMCKVYSDPQPHIQWLKHIEVNGSKIGPDNLPYVQILKTAGVNTTD 229
           +PA KTV      +F C     P P ++WLK    NG +  PD+       +  G     
Sbjct: 77  VPAAKTV------KFKCPSSGTPNPTLRWLK----NGKEFKPDH-------RIGGYKVRY 119

Query: 230 KEMEVLHLRNVSFEDAGEYTCLAGNSIGLSHHSAWLTVLEALEERP 275
               ++ + +V   D G YTC+  N  G  +H+  L V+E    RP
Sbjct: 120 ATWSII-MDSVVPSDKGNYTCIVENEYGSINHTYQLDVVERSPHRP 164


>gi|13186238 fibroblast growth factor receptor 1 isoform 5 precursor
           [Homo sapiens]
          Length = 302

 Score =  466 bits (1198), Expect = e-131
 Identities = 221/223 (99%), Positives = 221/223 (99%), Gaps = 2/223 (0%)

Query: 1   MWSWKCLLFWAVLVTATLCTARPSPTLPEQDALPSSEDDDDDDDSSSEEKETDNTKPN-- 58
           MWSWKCLLFWAVLVTATLCTARPSPTLPEQDALPSSEDDDDDDDSSSEEKETDNTKPN  
Sbjct: 1   MWSWKCLLFWAVLVTATLCTARPSPTLPEQDALPSSEDDDDDDDSSSEEKETDNTKPNRM 60

Query: 59  PVAPYWTSPEKMEKKLHAVPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPDHRIGGYKVR 118
           PVAPYWTSPEKMEKKLHAVPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPDHRIGGYKVR
Sbjct: 61  PVAPYWTSPEKMEKKLHAVPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPDHRIGGYKVR 120

Query: 119 YATWSIIMDSVVPSDKGNYTCIVENEYGSINHTYQLDVVERSPHRPILQAGLPANKTVAL 178
           YATWSIIMDSVVPSDKGNYTCIVENEYGSINHTYQLDVVERSPHRPILQAGLPANKTVAL
Sbjct: 121 YATWSIIMDSVVPSDKGNYTCIVENEYGSINHTYQLDVVERSPHRPILQAGLPANKTVAL 180

Query: 179 GSNVEFMCKVYSDPQPHIQWLKHIEVNGSKIGPDNLPYVQILK 221
           GSNVEFMCKVYSDPQPHIQWLKHIEVNGSKIGPDNLPYVQILK
Sbjct: 181 GSNVEFMCKVYSDPQPHIQWLKHIEVNGSKIGPDNLPYVQILK 223



 Score = 43.1 bits (100), Expect = 0.001
 Identities = 31/106 (29%), Positives = 46/106 (43%), Gaps = 18/106 (16%)

Query: 170 LPANKTVALGSNVEFMCKVYSDPQPHIQWLKHIEVNGSKIGPDNLPYVQILKTAGVNTTD 229
           +PA KTV      +F C     P P ++WLK    NG +  PD+       +  G     
Sbjct: 79  VPAAKTV------KFKCPSSGTPNPTLRWLK----NGKEFKPDH-------RIGGYKVRY 121

Query: 230 KEMEVLHLRNVSFEDAGEYTCLAGNSIGLSHHSAWLTVLEALEERP 275
               ++ + +V   D G YTC+  N  G  +H+  L V+E    RP
Sbjct: 122 ATWSII-MDSVVPSDKGNYTCIVENEYGSINHTYQLDVVERSPHRP 166


>gi|11321597 kinase insert domain receptor precursor [Homo sapiens]
          Length = 1356

 Score =  334 bits (857), Expect = 2e-91
 Identities = 239/652 (36%), Positives = 328/652 (50%), Gaps = 142/652 (21%)

Query: 133  DKGNYTCIVENEYGSINHTY--QLDVVERSPHRPILQAGLPANKTVALGSNVEFMCKVYS 190
            D+G+Y C+ ++      H    QL V+ER    P +   L  N+T ++G ++E  C    
Sbjct: 636  DQGDYVCLAQDRKTKKRHCVVRQLTVLERVA--PTITGNLE-NQTTSIGESIEVSCTASG 692

Query: 191  DPQPHIQWLKHIEVNGSKIGPDNLPYVQILKTAGVNTTDKEMEVLHLRNVSFEDAGEYTC 250
            +P P I W K  E               +++ +G+   D     L +R V  ED G YTC
Sbjct: 693  NPPPQIMWFKDNET--------------LVEDSGIVLKDGNRN-LTIRRVRKEDEGLYTC 737

Query: 251  LAGNSIGLSHHSAWLTVLEALEERPAVMTSPLYLEIIIYCTGAFLISCMVGSVIVYKMKS 310
             A + +G +   A+  ++E  +E+         LEIII   G  +I+     ++V  ++ 
Sbjct: 738  QACSVLGCAKVEAFF-IIEGAQEKTN-------LEIIIL-VGTAVIAMFFWLLLVIILR- 787

Query: 311  GTKKSDFHSQMAVHKLAKSIPLRRQVTVSADSSASMNSGVL--LVRPSRLSSSGTPMLAG 368
                                      TV   +   + +G L  ++ P  L          
Sbjct: 788  --------------------------TVKRANGGELKTGYLSIVMDPDELP--------- 812

Query: 369  VSEY--ELPEDP-RWELPRDRLVLGKPLGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKML 425
            + E+   LP D  +WE PRDRL LGKPLG G FGQV+ A+A G+DK    R   VAVKML
Sbjct: 813  LDEHCERLPYDASKWEFPRDRLKLGKPLGRGAFGQVIEADAFGIDKTATCRT--VAVKML 870

Query: 426  KSDATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQDG-PLYVIVEYASKGNLREYLQ- 483
            K  AT  +   L+SE++++  IG H N++NLLGACT+ G PL VIVE+   GNL  YL+ 
Sbjct: 871  KEGATHSEHRALMSELKILIHIGHHLNVVNLLGACTKPGGPLMVIVEFCKFGNLSTYLRS 930

Query: 484  ------------ARRPPGLEYC---------------------------------YNPSH 498
                        AR   G +Y                                       
Sbjct: 931  KRNEFVPYKTKGARFRQGKDYVGAIPVDLKRRLDSITSSQSSASSGFVEEKSLSDVEEEE 990

Query: 499  NPEEQ----LSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLA 554
             PE+     L+ + L+  ++QVA+GME+LAS+KCIHRDLAARN+L++E NV+KI DFGLA
Sbjct: 991  APEDLYKDFLTLEHLICYSFQVAKGMEFLASRKCIHRDLAARNILLSEKNVVKICDFGLA 1050

Query: 555  RDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVP 614
            RDI+    Y +  + RLP+KWMAPE +FDR+YT QSDVWSFGVLLWEIF+LG SPYPGV 
Sbjct: 1051 RDIYKDPDYVRKGDARLPLKWMAPETIFDRVYTIQSDVWSFGVLLWEIFSLGASPYPGVK 1110

Query: 615  VEELF-KLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRIVALTSNQ 673
            ++E F + LKEG RM  P   T E+Y  M DCWH  PSQRPTF +LVE L  ++   + Q
Sbjct: 1111 IDEEFCRRLKEGTRMRAPDYTTPEMYQTMLDCWHGEPSQRPTFSELVEHLGNLLQANAQQ 1170

Query: 674  EYLD-LSMPLDQYSPSFPDTRSSTCSSGEDSVFSHEPLP------EEPCLPR 718
            +  D + +P+           S T S  EDS  S    P      EE C P+
Sbjct: 1171 DGKDYIVLPI-----------SETLSMEEDSGLSLPTSPVSCMEEEEVCDPK 1211



 Score = 45.1 bits (105), Expect = 2e-04
 Identities = 35/143 (24%), Positives = 58/143 (40%), Gaps = 8/143 (5%)

Query: 62  PYWTSPEKMEKKLHAVPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPDHRIGGYKVRYAT 121
           P+      ME  + A    + V+      G P P ++W KNG   + +H I    V    
Sbjct: 328 PFVAFGSGMESLVEAT-VGERVRIPAKYLGYPPPEIKWYKNGIPLESNHTIKAGHV---- 382

Query: 122 WSIIMDSVVPSDKGNYTCIVENEYGSINHTYQLDVVERSPHRPILQAGLPANKTVALGSN 181
             + +  V   D GNYT I+ N       ++ + +V   P +   ++ +    +   G+ 
Sbjct: 383 --LTIMEVSERDTGNYTVILTNPISKEKQSHVVSLVVYVPPQIGEKSLISPVDSYQYGTT 440

Query: 182 VEFMCKVYSDPQP-HIQWLKHIE 203
               C VY+ P P HI W   +E
Sbjct: 441 QTLTCTVYAIPPPHHIHWYWQLE 463



 Score = 37.4 bits (85), Expect = 0.050
 Identities = 36/142 (25%), Positives = 55/142 (38%), Gaps = 24/142 (16%)

Query: 123 SIIMDSVVPSDKGNYTCIVENEYGSINHTYQLDVVERSPHRPILQ--AGLPANKTVALGS 180
           ++ +D V  SD+G YTC   +   +  ++  + V E+    P +   +G+ +     +G 
Sbjct: 291 TLTIDGVTRSDQGLYTCAASSGLMTKKNSTFVRVHEK----PFVAFGSGMESLVEATVGE 346

Query: 181 NVEFMCKVYSDPQPHIQWLKHIEVNGSKIGPDNLPYVQILKTAGVNTTDKEMEVLHLRNV 240
            V    K    P P I+W K    NG  +                N T K   VL +  V
Sbjct: 347 RVRIPAKYLGYPPPEIKWYK----NGIPLES--------------NHTIKAGHVLTIMEV 388

Query: 241 SFEDAGEYTCLAGNSIGLSHHS 262
           S  D G YT +  N I     S
Sbjct: 389 SERDTGNYTVILTNPISKEKQS 410



 Score = 32.7 bits (73), Expect = 1.2
 Identities = 15/59 (25%), Positives = 29/59 (49%), Gaps = 3/59 (5%)

Query: 81  KTVKFKCPSSGTPNPTLRWLKNGKEFKPDHRIGGYKVRYATWSIIMDSVVPSDKGNYTC 139
           ++++  C +SG P P + W K+ +    D    G  ++    ++ +  V   D+G YTC
Sbjct: 682 ESIEVSCTASGNPPPQIMWFKDNETLVED---SGIVLKDGNRNLTIRRVRKEDEGLYTC 737



 Score = 31.2 bits (69), Expect = 3.6
 Identities = 18/59 (30%), Positives = 29/59 (49%), Gaps = 2/59 (3%)

Query: 213 NLPYVQILKTAGVNTTDKEMEVLHLRNVSFEDAGEYTCLAGNSIGLSHHSA--WLTVLE 269
           NL  +  L     + +  ++ ++ L+N S +D G+Y CLA +      H     LTVLE
Sbjct: 605 NLDTLWKLNATMFSNSTNDILIMELKNASLQDQGDYVCLAQDRKTKKRHCVVRQLTVLE 663


>gi|10862701 ret proto-oncogene isoform c [Homo sapiens]
          Length = 1072

 Score =  328 bits (840), Expect = 1e-89
 Identities = 181/396 (45%), Positives = 248/396 (62%), Gaps = 30/396 (7%)

Query: 293  AFLISCMVGSVIVYKMKSGTKKSDFHS-QMAVHKLAKSIPLRRQVTVSADSSASMNSGVL 351
            +F++S ++ +  ++       K    S +M   + A++ P      VS  SS +      
Sbjct: 645  SFIVSVLLSAFCIHCYHKFAHKPPISSAEMTFRRPAQAFP------VSYSSSGAR----- 693

Query: 352  LVRPSRLSSSGTPMLAGVSEYELPEDPRWELPRDRLVLGKPLGEGCFGQVVLAEAIGLDK 411
              RPS  S         V  +++ EDP+WE PR  LVLGK LGEG FG+VV A A  L K
Sbjct: 694  --RPSLDSMENQ---VSVDAFKILEDPKWEFPRKNLVLGKTLGEGEFGKVVKATAFHL-K 747

Query: 412  DKPNRVTKVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVE 471
             +    T VAVKMLK +A+  +L DL+SE  ++K +  H ++I L GAC+QDGPL +IVE
Sbjct: 748  GRAGYTT-VAVKMLKENASPSELRDLLSEFNVLKQVN-HPHVIKLYGACSQDGPLLLIVE 805

Query: 472  YASKGNLREYLQARRPPGLEYCYNPS--------HNPEEQLSSKDLVSCAYQVARGMEYL 523
            YA  G+LR +L+  R  G  Y  +          H  E  L+  DL+S A+Q+++GM+YL
Sbjct: 806  YAKYGSLRGFLRESRKVGPGYLGSGGSRNSSSLDHPDERALTMGDLISFAWQISQGMQYL 865

Query: 524  ASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHHIDYYKKTTNGRLPVKWMAPEALFD 583
            A  K +HRDLAARN+LV E   MKI+DFGL+RD++  D Y K + GR+PVKWMA E+LFD
Sbjct: 866  AEMKLVHRDLAARNILVAEGRKMKISDFGLSRDVYEEDSYVKRSQGRIPVKWMAIESLFD 925

Query: 584  RIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVEELFKLLKEGHRMDKPSNCTNELYMMMR 643
             IYT QSDVWSFGVLLWEI TLGG+PYPG+P E LF LLK GHRM++P NC+ E+Y +M 
Sbjct: 926  HIYTTQSDVWSFGVLLWEIVTLGGNPYPGIPPERLFNLLKTGHRMERPDNCSEEMYRLML 985

Query: 644  DCWHAVPSQRPTFKQLVEDLDRIVALTSNQEYLDLS 679
             CW   P +RP F  + +DL+++  +   ++YLDL+
Sbjct: 986  QCWKQEPDKRPVFADISKDLEKM--MVKRRDYLDLA 1019


>gi|10862703 ret proto-oncogene isoform a [Homo sapiens]
          Length = 1114

 Score =  328 bits (840), Expect = 1e-89
 Identities = 181/396 (45%), Positives = 248/396 (62%), Gaps = 30/396 (7%)

Query: 293  AFLISCMVGSVIVYKMKSGTKKSDFHS-QMAVHKLAKSIPLRRQVTVSADSSASMNSGVL 351
            +F++S ++ +  ++       K    S +M   + A++ P      VS  SS +      
Sbjct: 645  SFIVSVLLSAFCIHCYHKFAHKPPISSAEMTFRRPAQAFP------VSYSSSGAR----- 693

Query: 352  LVRPSRLSSSGTPMLAGVSEYELPEDPRWELPRDRLVLGKPLGEGCFGQVVLAEAIGLDK 411
              RPS  S         V  +++ EDP+WE PR  LVLGK LGEG FG+VV A A  L K
Sbjct: 694  --RPSLDSMENQ---VSVDAFKILEDPKWEFPRKNLVLGKTLGEGEFGKVVKATAFHL-K 747

Query: 412  DKPNRVTKVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVE 471
             +    T VAVKMLK +A+  +L DL+SE  ++K +  H ++I L GAC+QDGPL +IVE
Sbjct: 748  GRAGYTT-VAVKMLKENASPSELRDLLSEFNVLKQVN-HPHVIKLYGACSQDGPLLLIVE 805

Query: 472  YASKGNLREYLQARRPPGLEYCYNPS--------HNPEEQLSSKDLVSCAYQVARGMEYL 523
            YA  G+LR +L+  R  G  Y  +          H  E  L+  DL+S A+Q+++GM+YL
Sbjct: 806  YAKYGSLRGFLRESRKVGPGYLGSGGSRNSSSLDHPDERALTMGDLISFAWQISQGMQYL 865

Query: 524  ASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHHIDYYKKTTNGRLPVKWMAPEALFD 583
            A  K +HRDLAARN+LV E   MKI+DFGL+RD++  D Y K + GR+PVKWMA E+LFD
Sbjct: 866  AEMKLVHRDLAARNILVAEGRKMKISDFGLSRDVYEEDSYVKRSQGRIPVKWMAIESLFD 925

Query: 584  RIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVEELFKLLKEGHRMDKPSNCTNELYMMMR 643
             IYT QSDVWSFGVLLWEI TLGG+PYPG+P E LF LLK GHRM++P NC+ E+Y +M 
Sbjct: 926  HIYTTQSDVWSFGVLLWEIVTLGGNPYPGIPPERLFNLLKTGHRMERPDNCSEEMYRLML 985

Query: 644  DCWHAVPSQRPTFKQLVEDLDRIVALTSNQEYLDLS 679
             CW   P +RP F  + +DL+++  +   ++YLDL+
Sbjct: 986  QCWKQEPDKRPVFADISKDLEKM--MVKRRDYLDLA 1019


>gi|156104876 fms-related tyrosine kinase 1 isoform 1 precursor [Homo
            sapiens]
          Length = 1338

 Score =  321 bits (822), Expect = 2e-87
 Identities = 219/613 (35%), Positives = 307/613 (50%), Gaps = 118/613 (19%)

Query: 121  TWSIIMDSVVPSDKGNYTCIVENEYGSINHTYQLDVVERSPHRPILQAGLPANKTVALGS 180
            T ++ + +V   D G Y C   N Y       + ++  R    P L   L ++ TVA+ S
Sbjct: 618  TLNLTIMNVSLQDSGTYACRARNVYTGEEILQKKEITIRDQEAPYLLRNL-SDHTVAISS 676

Query: 181  NVEFMCKVYSDPQPHIQWLKHIEVNGSKIGPDNLPYVQILKTAGVNTTDKEMEVLHLRNV 240
            +    C     P+P I W K    N  KI  +      I+   G +T       L +  V
Sbjct: 677  STTLDCHANGVPEPQITWFK----NNHKIQQEP----GIILGPGSST-------LFIERV 721

Query: 241  SFEDAGEYTCLAGNSIGLSHHSAWLTVLEALEERPAVMTSPLYLEIIIYCTGAFLISCMV 300
            + ED G Y C A N  G    SA+LTV    ++    +     + +   C  A L   ++
Sbjct: 722  TEEDEGVYHCKATNQKGSVESSAYLTVQGTSDKSNLEL-----ITLTCTCVAATLFWLLL 776

Query: 301  GSVIVYKMKSGTK--KSDFHSQMAVHKLAKSIPLRRQVTVSADSSASMNSGVLLVRPSRL 358
             ++ + KMK  +   K+D+   +++      +PL  Q                       
Sbjct: 777  -TLFIRKMKRSSSEIKTDY---LSIIMDPDEVPLDEQCE--------------------- 811

Query: 359  SSSGTPMLAGVSEYELPEDP-RWELPRDRLVLGKPLGEGCFGQVVLAEAIGLDKDKPNRV 417
                           LP D  +WE  R+RL LGK LG G FG+VV A A G+ K    R 
Sbjct: 812  --------------RLPYDASKWEFARERLKLGKSLGRGAFGKVVQASAFGIKKSPTCRT 857

Query: 418  TKVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKNIINLLGACT-QDGPLYVIVEYASKG 476
              VAVKMLK  AT  +   L++E++++  IG H N++NLLGACT Q GPL VIVEY   G
Sbjct: 858  --VAVKMLKEGATASEYKALMTELKILTHIGHHLNVVNLLGACTKQGGPLMVIVEYCKYG 915

Query: 477  NLREYLQARRP--------------------PGLEYCYNPSHNP---------------- 500
            NL  YL+++R                     PGLE    P  +                 
Sbjct: 916  NLSNYLKSKRDLFFLNKDAALHMEPKKEKMEPGLEQGKKPRLDSVTSSESFASSGFQEDK 975

Query: 501  ---------------EEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNV 545
                           +E ++ +DL+S ++QVARGME+L+S+KCIHRDLAARN+L++E+NV
Sbjct: 976  SLSDVEEEEDSDGFYKEPITMEDLISYSFQVARGMEFLSSRKCIHRDLAARNILLSENNV 1035

Query: 546  MKIADFGLARDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTL 605
            +KI DFGLARDI+    Y +  + RLP+KWMAPE++FD+IY+ +SDVWS+GVLLWEIF+L
Sbjct: 1036 VKICDFGLARDIYKNPDYVRKGDTRLPLKWMAPESIFDKIYSTKSDVWSYGVLLWEIFSL 1095

Query: 606  GGSPYPGVPVEELF-KLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQLVEDLD 664
            GGSPYPGV ++E F   L+EG RM  P   T E+Y +M DCWH  P +RP F +LVE L 
Sbjct: 1096 GGSPYPGVQMDEDFCSRLREGMRMRAPEYSTPEIYQIMLDCWHRDPKERPRFAELVEKLG 1155

Query: 665  RIVALTSNQEYLD 677
             ++     Q+  D
Sbjct: 1156 DLLQANVQQDGKD 1168



 Score = 47.4 bits (111), Expect = 5e-05
 Identities = 35/143 (24%), Positives = 59/143 (41%), Gaps = 14/143 (9%)

Query: 65  TSPEKMEKKLHAVPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPDHRIGGYKVRYAT--W 122
           T   + ++ L  V   ++ +        P+P + WLK+G              RY T  +
Sbjct: 335 TVKHRKQQVLETVAGKRSYRLSMKVKAFPSPEVVWLKDGLPATEK------SARYLTRGY 388

Query: 123 SIIMDSVVPSDKGNYTCIVE----NEYGSINHTYQLDVVERSPHRPILQAGLPANKTVAL 178
           S+I+  V   D GNYT ++     N + ++  T  ++V  +   + +  +  P      L
Sbjct: 389 SLIIKDVTEEDAGNYTILLSIKQSNVFKNLTATLIVNVKPQIYEKAV--SSFPDPALYPL 446

Query: 179 GSNVEFMCKVYSDPQPHIQWLKH 201
           GS     C  Y  PQP I+W  H
Sbjct: 447 GSRQILTCTAYGIPQPTIKWFWH 469



 Score = 40.8 bits (94), Expect = 0.005
 Identities = 20/82 (24%), Positives = 38/82 (46%), Gaps = 3/82 (3%)

Query: 75  HAVPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPDHRIGGYKVRYATWSIIMDSVVPSDK 134
           H V  + +    C ++G P P + W KN  + + +    G  +   + ++ ++ V   D+
Sbjct: 670 HTVAISSSTTLDCHANGVPEPQITWFKNNHKIQQE---PGIILGPGSSTLFIERVTEEDE 726

Query: 135 GNYTCIVENEYGSINHTYQLDV 156
           G Y C   N+ GS+  +  L V
Sbjct: 727 GVYHCKATNQKGSVESSAYLTV 748



 Score = 35.0 bits (79), Expect = 0.25
 Identities = 38/134 (28%), Positives = 59/134 (44%), Gaps = 29/134 (21%)

Query: 124 IIMDSVVPSDKGNYTCIVEN--EYGSIN---HTY-QLDVVERSPHRPILQAGLPANKTVA 177
           + +D +   DKG YTC V +   + S+N   H Y +  +  +   + +L+       TVA
Sbjct: 296 LTIDKMQNKDKGLYTCRVRSGPSFKSVNTSVHIYDKAFITVKHRKQQVLE-------TVA 348

Query: 178 LGSNVEFMCKVYSDPQPHIQWLKHIEVNGSKIGPDNLPYVQILKTAGVNTTDKEMEVLHL 237
              +     KV + P P + WLK           D LP  +  K+A   T       L +
Sbjct: 349 GKRSYRLSMKVKAFPSPEVVWLK-----------DGLPATE--KSARYLTRGYS---LII 392

Query: 238 RNVSFEDAGEYTCL 251
           ++V+ EDAG YT L
Sbjct: 393 KDVTEEDAGNYTIL 406


>gi|148005039 v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene
           homolog isoform 2 precursor [Homo sapiens]
          Length = 972

 Score =  269 bits (688), Expect = 6e-72
 Identities = 212/688 (30%), Positives = 321/688 (46%), Gaps = 156/688 (22%)

Query: 123 SIIMDSVVPSDKGNYTCIVENEYGSINHTYQLDVVERSPHRPILQAGLPANKTVAL--GS 180
           ++ + S   +D G + C   N +GS N T  L+VV++      +      N TV +  G 
Sbjct: 274 TLTISSARVNDSGVFMCYANNTFGSANVTTTLEVVDKG----FINIFPMINTTVFVNDGE 329

Query: 181 NVEFMCKVYSDPQP-HIQWLKHIEVNGSKIGPDNLPYVQILKTAGVNTTDKEMEVLHLRN 239
           NV+ + +  + P+P H QW+        K   ++ P       +   +  + +  LHL  
Sbjct: 330 NVDLIVEYEAFPKPEHQQWIYMNRTFTDKW--EDYP------KSENESNIRYVSELHLTR 381

Query: 240 VSFEDAGEYTCLAGNSIGLSHHSAWLTVLEALEERPAVMTSPLYLEIIIYCTGAFLISCM 299
           +   + G YT L  N    S  +A +     +  +P ++T    +  ++ C  A      
Sbjct: 382 LKGTEGGTYTFLVSN----SDVNAAIAFNVYVNTKPEILTYDRLVNGMLQCVAAGFPE-- 435

Query: 300 VGSVIVYKMKSGTKKSDFHSQMA--VHKLAKSIPLRRQVTV--SADSSASMNSGVL---- 351
               I +    GT++    S +   V  L  S P   ++ V  S DSSA  ++G +    
Sbjct: 436 --PTIDWYFCPGTEQRCSASVLPVDVQTLNSSGPPFGKLVVQSSIDSSAFKHNGTVECKA 493

Query: 352 -----------------LVRPSRLSSSGTPMLAG-------------VSEYELPEDPRWE 381
                             + P  L    TP+L G             +  Y+  + P +E
Sbjct: 494 YNDVGKTSAYFNFAFKEQIHPHTLF---TPLLIGFVIVAGMMCIIVMILTYKYLQKPMYE 550

Query: 382 ---------------------LPRD--------RLVLGKPLGEGCFGQVVLAEAIGLDKD 412
                                LP D        RL  GK LG G FG+VV A A GL K 
Sbjct: 551 VQWKVVEEINGNNYVYIDPTQLPYDHKWEFPRNRLSFGKTLGAGAFGKVVEATAYGLIKS 610

Query: 413 KPNRVTKVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEY 472
             +    VAVKMLK  A   +   L+SE++++  +G H NI+NLLGACT  GP  VI EY
Sbjct: 611 --DAAMTVAVKMLKPSAHLTEREALMSELKVLSYLGNHMNIVNLLGACTIGGPTLVITEY 668

Query: 473 ASKGNLREYLQARR--------------------------------------PPGLEYC- 493
              G+L  +L+ +R                                       PG+ Y  
Sbjct: 669 CCYGDLLNFLRRKRDSFICSKQEDHAEAALYKNLLHSKESSCSDSTNEYMDMKPGVSYVV 728

Query: 494 -------------------YNPSHNPEEQLS--SKDLVSCAYQVARGMEYLASKKCIHRD 532
                                P+   +++L+   +DL+S +YQVA+GM +LASK CIHRD
Sbjct: 729 PTKADKRRSVRIGSYIERDVTPAIMEDDELALDLEDLLSFSYQVAKGMAFLASKNCIHRD 788

Query: 533 LAARNVLVTEDNVMKIADFGLARDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDV 592
           LAARN+L+T   + KI DFGLARDI +   Y    N RLPVKWMAPE++F+ +YT +SDV
Sbjct: 789 LAARNILLTHGRITKICDFGLARDIKNDSNYVVKGNARLPVKWMAPESIFNCVYTFESDV 848

Query: 593 WSFGVLLWEIFTLGGSPYPGVPVE-ELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAVPS 651
           WS+G+ LWE+F+LG SPYPG+PV+ + +K++KEG RM  P +   E+Y +M+ CW A P 
Sbjct: 849 WSYGIFLWELFSLGSSPYPGMPVDSKFYKMIKEGFRMLSPEHAPAEMYDIMKTCWDADPL 908

Query: 652 QRPTFKQLVEDLDRIVALTSNQEYLDLS 679
           +RPTFKQ+V+ +++ ++ ++N  Y +L+
Sbjct: 909 KRPTFKQIVQLIEKQISESTNHIYSNLA 936


>gi|4557695 v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene
           homolog isoform 1 precursor [Homo sapiens]
          Length = 976

 Score =  268 bits (684), Expect = 2e-71
 Identities = 150/370 (40%), Positives = 209/370 (56%), Gaps = 67/370 (18%)

Query: 373 ELPEDPRWELPRDRLVLGKPLGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEK 432
           +LP D +WE PR+RL  GK LG G FG+VV A A GL K   +    VAVKMLK  A   
Sbjct: 575 QLPYDHKWEFPRNRLSFGKTLGAGAFGKVVEATAYGLIKS--DAAMTVAVKMLKPSAHLT 632

Query: 433 DLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIV---------------------- 470
           +   L+SE++++  +G H NI+NLLGACT  GP  VI                       
Sbjct: 633 EREALMSELKVLSYLGNHMNIVNLLGACTIGGPTLVITEYCCYGDLLNFLRRKRDSFICS 692

Query: 471 ------------------EYASKGNLREYLQARRPPGLEYCYNPS--------------- 497
                             E +   +  EY+  +  PG+ Y                    
Sbjct: 693 KQEDHAEAALYKNLLHSKESSCSDSTNEYMDMK--PGVSYVVPTKADKRRSVRIGSYIER 750

Query: 498 -------HNPEEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIAD 550
                   + E  L  +DL+S +YQVA+GM +LASK CIHRDLAARN+L+T   + KI D
Sbjct: 751 DVTPAIMEDDELALDLEDLLSFSYQVAKGMAFLASKNCIHRDLAARNILLTHGRITKICD 810

Query: 551 FGLARDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPY 610
           FGLARDI +   Y    N RLPVKWMAPE++F+ +YT +SDVWS+G+ LWE+F+LG SPY
Sbjct: 811 FGLARDIKNDSNYVVKGNARLPVKWMAPESIFNCVYTFESDVWSYGIFLWELFSLGSSPY 870

Query: 611 PGVPVE-ELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRIVAL 669
           PG+PV+ + +K++KEG RM  P +   E+Y +M+ CW A P +RPTFKQ+V+ +++ ++ 
Sbjct: 871 PGMPVDSKFYKMIKEGFRMLSPEHAPAEMYDIMKTCWDADPLKRPTFKQIVQLIEKQISE 930

Query: 670 TSNQEYLDLS 679
           ++N  Y +L+
Sbjct: 931 STNHIYSNLA 940



 Score = 37.0 bits (84), Expect = 0.065
 Identities = 39/174 (22%), Positives = 73/174 (41%), Gaps = 19/174 (10%)

Query: 123 SIIMDSVVPSDKGNYTCIVENEYGSINHTYQLDVVERSPHRPILQAGLPANKTVAL--GS 180
           ++ + S   +D G + C   N +GS N T  L+VV++      +      N TV +  G 
Sbjct: 274 TLTISSARVNDSGVFMCYANNTFGSANVTTTLEVVDKG----FINIFPMINTTVFVNDGE 329

Query: 181 NVEFMCKVYSDPQP-HIQWLKHIEVNGSKIGPDNLPYVQILKTAGVNTTDKEMEVLHLRN 239
           NV+ + +  + P+P H QW+        K   ++ P       +   +  + +  LHL  
Sbjct: 330 NVDLIVEYEAFPKPEHQQWIYMNRTFTDKW--EDYP------KSENESNIRYVSELHLTR 381

Query: 240 VSFEDAGEYTCLAGNSIGLSHHSAWLTVLEALEERPAVMTSPLYLEIIIYCTGA 293
           +   + G YT L  N    S  +A +     +  +P ++T    +  ++ C  A
Sbjct: 382 LKGTEGGTYTFLVSN----SDVNAAIAFNVYVNTKPEILTYDRLVNGMLQCVAA 431


>gi|4885631 tyrosine kinase with immunoglobulin-like and EGF-like
            domains 1 [Homo sapiens]
          Length = 1138

 Score =  250 bits (638), Expect = 4e-66
 Identities = 137/288 (47%), Positives = 185/288 (64%), Gaps = 10/288 (3%)

Query: 393  LGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKN 452
            +GEG FGQV+ A  I  D  K N     A+KMLK  A+E D  D   E+E++  +G H N
Sbjct: 845  IGEGNFGQVIRA-MIKKDGLKMN----AAIKMLKEYASENDHRDFAGELEVLCKLGHHPN 899

Query: 453  IINLLGACTQDGPLYVIVEYASKGNLREYLQARRPPGLEYCYNPSHNPEEQLSSKDLVSC 512
            IINLLGAC   G LY+ +EYA  GNL ++L+  R    +  +   H     LSS+ L+  
Sbjct: 900  IINLLGACKNRGYLYIAIEYAPYGNLLDFLRKSRVLETDPAFAREHGTASTLSSRQLLRF 959

Query: 513  AYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHHIDYYKKTTNGRLP 572
            A   A GM+YL+ K+ IHRDLAARNVLV E+   KIADFGL+R     + Y K T GRLP
Sbjct: 960  ASDAANGMQYLSEKQFIHRDLAARNVLVGENLASKIADFGLSRG---EEVYVKKTMGRLP 1016

Query: 573  VKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVEELFKLLKEGHRMDKPS 632
            V+WMA E+L   +YT +SDVWSFGVLLWEI +LGG+PY G+   EL++ L +G+RM++P 
Sbjct: 1017 VRWMAIESLNYSVYTTKSDVWSFGVLLWEIVSLGGTPYCGMTCAELYEKLPQGYRMEQPR 1076

Query: 633  NCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRIVALTSNQEYLDLSM 680
            NC +E+Y +MR CW   P +RP F Q+   L R+  L + + Y+++S+
Sbjct: 1077 NCDDEVYELMRQCWRDRPYERPPFAQIALQLGRM--LEARKAYVNMSL 1122


>gi|88758596 TEK tyrosine kinase, endothelial precursor [Homo sapiens]
          Length = 1124

 Score =  244 bits (622), Expect = 3e-64
 Identities = 128/275 (46%), Positives = 180/275 (65%), Gaps = 8/275 (2%)

Query: 393  LGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKN 452
            +GEG FGQV+ A        K       A+K +K  A++ D  D   E+E++  +G H N
Sbjct: 830  IGEGNFGQVLKARI-----KKDGLRMDAAIKRMKEYASKDDHRDFAGELEVLCKLGHHPN 884

Query: 453  IINLLGACTQDGPLYVIVEYASKGNLREYLQARRPPGLEYCYNPSHNPEEQLSSKDLVSC 512
            IINLLGAC   G LY+ +EYA  GNL ++L+  R    +  +  +++    LSS+ L+  
Sbjct: 885  IINLLGACEHRGYLYLAIEYAPHGNLLDFLRKSRVLETDPAFAIANSTASTLSSQQLLHF 944

Query: 513  AYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHHIDYYKKTTNGRLP 572
            A  VARGM+YL+ K+ IHRDLAARN+LV E+ V KIADFGL+R     + Y K T GRLP
Sbjct: 945  AADVARGMDYLSQKQFIHRDLAARNILVGENYVAKIADFGLSRGQ---EVYVKKTMGRLP 1001

Query: 573  VKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVEELFKLLKEGHRMDKPS 632
            V+WMA E+L   +YT  SDVWS+GVLLWEI +LGG+PY G+   EL++ L +G+R++KP 
Sbjct: 1002 VRWMAIESLNYSVYTTNSDVWSYGVLLWEIVSLGGTPYCGMTCAELYEKLPQGYRLEKPL 1061

Query: 633  NCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRIV 667
            NC +E+Y +MR CW   P +RP+F Q++  L+R++
Sbjct: 1062 NCDDEVYDLMRQCWREKPYERPSFAQILVSLNRML 1096


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.317    0.133    0.407 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 31,329,737
Number of Sequences: 37866
Number of extensions: 1578775
Number of successful extensions: 14214
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 702
Number of HSP's successfully gapped in prelim test: 410
Number of HSP's that attempted gapping in prelim test: 7813
Number of HSP's gapped (non-prelim): 3346
length of query: 731
length of database: 18,247,518
effective HSP length: 110
effective length of query: 621
effective length of database: 14,082,258
effective search space: 8745082218
effective search space used: 8745082218
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 66 (30.0 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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