BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|4557555 endoglin isoform 2 precursor [Homo sapiens] (625 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|4557555 endoglin isoform 2 precursor [Homo sapiens] 1252 0.0 gi|168693647 endoglin isoform 1 precursor [Homo sapiens] 1236 0.0 gi|56682966 transforming growth factor, beta receptor III [Homo ... 56 1e-07 gi|226371775 sex hormone-binding globulin isoform 2 precursor [H... 33 0.79 gi|7382460 sex hormone-binding globulin isoform 1 precursor [Hom... 33 0.79 gi|148746189 multiple PDZ domain protein [Homo sapiens] 32 1.3 gi|239748362 PREDICTED: hypothetical protein XP_002346639 [Homo ... 31 3.9 gi|27734871 regulatory factor X, 6 [Homo sapiens] 30 5.1 gi|197245373 proline rich 22 isoform 1 [Homo sapiens] 30 6.7 gi|23503299 proline rich 22 isoform 2 [Homo sapiens] 30 6.7 gi|239749012 PREDICTED: hypothetical protein XP_002346880 [Homo ... 30 6.7 gi|239750729 PREDICTED: hypothetical protein XP_002347517 [Homo ... 30 8.7 gi|7662346 ADNP homeobox 2 [Homo sapiens] 30 8.7 >gi|4557555 endoglin isoform 2 precursor [Homo sapiens] Length = 625 Score = 1252 bits (3240), Expect = 0.0 Identities = 625/625 (100%), Positives = 625/625 (100%) Query: 1 MDRGTLPLAVALLLASCSLSPTSLAETVHCDLQPVGPERGEVTYTTSQVSKGCVAQAPNA 60 MDRGTLPLAVALLLASCSLSPTSLAETVHCDLQPVGPERGEVTYTTSQVSKGCVAQAPNA Sbjct: 1 MDRGTLPLAVALLLASCSLSPTSLAETVHCDLQPVGPERGEVTYTTSQVSKGCVAQAPNA 60 Query: 61 ILEVHVLFLEFPTGPSQLELTLQASKQNGTWPREVLLVLSVNSSVFLHLQALGIPLHLAY 120 ILEVHVLFLEFPTGPSQLELTLQASKQNGTWPREVLLVLSVNSSVFLHLQALGIPLHLAY Sbjct: 61 ILEVHVLFLEFPTGPSQLELTLQASKQNGTWPREVLLVLSVNSSVFLHLQALGIPLHLAY 120 Query: 121 NSSLVTFQEPPGVNTTELPSFPKTQILEWAAERGPITSAAELNDPQSILLRLGQAQGSLS 180 NSSLVTFQEPPGVNTTELPSFPKTQILEWAAERGPITSAAELNDPQSILLRLGQAQGSLS Sbjct: 121 NSSLVTFQEPPGVNTTELPSFPKTQILEWAAERGPITSAAELNDPQSILLRLGQAQGSLS 180 Query: 181 FCMLEASQDMGRTLEWRPRTPALVRGCHLEGVAGHKEAHILRVLPGHSAGPRTVTVKVEL 240 FCMLEASQDMGRTLEWRPRTPALVRGCHLEGVAGHKEAHILRVLPGHSAGPRTVTVKVEL Sbjct: 181 FCMLEASQDMGRTLEWRPRTPALVRGCHLEGVAGHKEAHILRVLPGHSAGPRTVTVKVEL 240 Query: 241 SCAPGDLDAVLILQGPPYVSWLIDANHNMQIWTTGEYSFKIFPEKNIRGFKLPDTPQGLL 300 SCAPGDLDAVLILQGPPYVSWLIDANHNMQIWTTGEYSFKIFPEKNIRGFKLPDTPQGLL Sbjct: 241 SCAPGDLDAVLILQGPPYVSWLIDANHNMQIWTTGEYSFKIFPEKNIRGFKLPDTPQGLL 300 Query: 301 GEARMLNASIVASFVELPLASIVSLHASSCGGRLQTSPAPIQTTPPKDTCSPELLMSLIQ 360 GEARMLNASIVASFVELPLASIVSLHASSCGGRLQTSPAPIQTTPPKDTCSPELLMSLIQ Sbjct: 301 GEARMLNASIVASFVELPLASIVSLHASSCGGRLQTSPAPIQTTPPKDTCSPELLMSLIQ 360 Query: 361 TKCADDAMTLVLKKELVAHLKCTITGLTFWDPSCEAEDRGDKFVLRSAYSSCGMQVSASM 420 TKCADDAMTLVLKKELVAHLKCTITGLTFWDPSCEAEDRGDKFVLRSAYSSCGMQVSASM Sbjct: 361 TKCADDAMTLVLKKELVAHLKCTITGLTFWDPSCEAEDRGDKFVLRSAYSSCGMQVSASM 420 Query: 421 ISNEAVVNILSSSSPQRKKVHCLNMDSLSFQLGLYLSPHFLQASNTIEPGQQSFVQVRVS 480 ISNEAVVNILSSSSPQRKKVHCLNMDSLSFQLGLYLSPHFLQASNTIEPGQQSFVQVRVS Sbjct: 421 ISNEAVVNILSSSSPQRKKVHCLNMDSLSFQLGLYLSPHFLQASNTIEPGQQSFVQVRVS 480 Query: 481 PSVSEFLLQLDSCHLDLGPEGGTVELIQGRAAKGNCVSLLSPSPEGDPRFSFLLHFYTVP 540 PSVSEFLLQLDSCHLDLGPEGGTVELIQGRAAKGNCVSLLSPSPEGDPRFSFLLHFYTVP Sbjct: 481 PSVSEFLLQLDSCHLDLGPEGGTVELIQGRAAKGNCVSLLSPSPEGDPRFSFLLHFYTVP 540 Query: 541 IPKTGTLSCTVALRPKTGSQDQEVHRTVFMRLNIISPDLSGCTSKGLVLPAVLGITFGAF 600 IPKTGTLSCTVALRPKTGSQDQEVHRTVFMRLNIISPDLSGCTSKGLVLPAVLGITFGAF Sbjct: 541 IPKTGTLSCTVALRPKTGSQDQEVHRTVFMRLNIISPDLSGCTSKGLVLPAVLGITFGAF 600 Query: 601 LIGALLTAALWYIYSHTREYPRPPQ 625 LIGALLTAALWYIYSHTREYPRPPQ Sbjct: 601 LIGALLTAALWYIYSHTREYPRPPQ 625 >gi|168693647 endoglin isoform 1 precursor [Homo sapiens] Length = 658 Score = 1236 bits (3197), Expect = 0.0 Identities = 618/618 (100%), Positives = 618/618 (100%) Query: 1 MDRGTLPLAVALLLASCSLSPTSLAETVHCDLQPVGPERGEVTYTTSQVSKGCVAQAPNA 60 MDRGTLPLAVALLLASCSLSPTSLAETVHCDLQPVGPERGEVTYTTSQVSKGCVAQAPNA Sbjct: 1 MDRGTLPLAVALLLASCSLSPTSLAETVHCDLQPVGPERGEVTYTTSQVSKGCVAQAPNA 60 Query: 61 ILEVHVLFLEFPTGPSQLELTLQASKQNGTWPREVLLVLSVNSSVFLHLQALGIPLHLAY 120 ILEVHVLFLEFPTGPSQLELTLQASKQNGTWPREVLLVLSVNSSVFLHLQALGIPLHLAY Sbjct: 61 ILEVHVLFLEFPTGPSQLELTLQASKQNGTWPREVLLVLSVNSSVFLHLQALGIPLHLAY 120 Query: 121 NSSLVTFQEPPGVNTTELPSFPKTQILEWAAERGPITSAAELNDPQSILLRLGQAQGSLS 180 NSSLVTFQEPPGVNTTELPSFPKTQILEWAAERGPITSAAELNDPQSILLRLGQAQGSLS Sbjct: 121 NSSLVTFQEPPGVNTTELPSFPKTQILEWAAERGPITSAAELNDPQSILLRLGQAQGSLS 180 Query: 181 FCMLEASQDMGRTLEWRPRTPALVRGCHLEGVAGHKEAHILRVLPGHSAGPRTVTVKVEL 240 FCMLEASQDMGRTLEWRPRTPALVRGCHLEGVAGHKEAHILRVLPGHSAGPRTVTVKVEL Sbjct: 181 FCMLEASQDMGRTLEWRPRTPALVRGCHLEGVAGHKEAHILRVLPGHSAGPRTVTVKVEL 240 Query: 241 SCAPGDLDAVLILQGPPYVSWLIDANHNMQIWTTGEYSFKIFPEKNIRGFKLPDTPQGLL 300 SCAPGDLDAVLILQGPPYVSWLIDANHNMQIWTTGEYSFKIFPEKNIRGFKLPDTPQGLL Sbjct: 241 SCAPGDLDAVLILQGPPYVSWLIDANHNMQIWTTGEYSFKIFPEKNIRGFKLPDTPQGLL 300 Query: 301 GEARMLNASIVASFVELPLASIVSLHASSCGGRLQTSPAPIQTTPPKDTCSPELLMSLIQ 360 GEARMLNASIVASFVELPLASIVSLHASSCGGRLQTSPAPIQTTPPKDTCSPELLMSLIQ Sbjct: 301 GEARMLNASIVASFVELPLASIVSLHASSCGGRLQTSPAPIQTTPPKDTCSPELLMSLIQ 360 Query: 361 TKCADDAMTLVLKKELVAHLKCTITGLTFWDPSCEAEDRGDKFVLRSAYSSCGMQVSASM 420 TKCADDAMTLVLKKELVAHLKCTITGLTFWDPSCEAEDRGDKFVLRSAYSSCGMQVSASM Sbjct: 361 TKCADDAMTLVLKKELVAHLKCTITGLTFWDPSCEAEDRGDKFVLRSAYSSCGMQVSASM 420 Query: 421 ISNEAVVNILSSSSPQRKKVHCLNMDSLSFQLGLYLSPHFLQASNTIEPGQQSFVQVRVS 480 ISNEAVVNILSSSSPQRKKVHCLNMDSLSFQLGLYLSPHFLQASNTIEPGQQSFVQVRVS Sbjct: 421 ISNEAVVNILSSSSPQRKKVHCLNMDSLSFQLGLYLSPHFLQASNTIEPGQQSFVQVRVS 480 Query: 481 PSVSEFLLQLDSCHLDLGPEGGTVELIQGRAAKGNCVSLLSPSPEGDPRFSFLLHFYTVP 540 PSVSEFLLQLDSCHLDLGPEGGTVELIQGRAAKGNCVSLLSPSPEGDPRFSFLLHFYTVP Sbjct: 481 PSVSEFLLQLDSCHLDLGPEGGTVELIQGRAAKGNCVSLLSPSPEGDPRFSFLLHFYTVP 540 Query: 541 IPKTGTLSCTVALRPKTGSQDQEVHRTVFMRLNIISPDLSGCTSKGLVLPAVLGITFGAF 600 IPKTGTLSCTVALRPKTGSQDQEVHRTVFMRLNIISPDLSGCTSKGLVLPAVLGITFGAF Sbjct: 541 IPKTGTLSCTVALRPKTGSQDQEVHRTVFMRLNIISPDLSGCTSKGLVLPAVLGITFGAF 600 Query: 601 LIGALLTAALWYIYSHTR 618 LIGALLTAALWYIYSHTR Sbjct: 601 LIGALLTAALWYIYSHTR 618 >gi|56682966 transforming growth factor, beta receptor III [Homo sapiens] Length = 851 Score = 55.8 bits (133), Expect = 1e-07 Identities = 89/372 (23%), Positives = 150/372 (40%), Gaps = 37/372 (9%) Query: 8 LAVALLLASCSLSPTSLAETVHCDLQPVGPERG-EVTYTTSQVSKGCVAQAPNAI-LEVH 65 +A+ L++SC L+ C+L PV + + V GC ++ + EVH Sbjct: 7 IAIFALMSSC-LATAGPEPGALCELSPVSASHPVQALMESFTVLSGCASRGTTGLPQEVH 65 Query: 66 VLFLEFP-TGPSQL--ELTLQASKQNGTWPREVLLVLSVNSS--VFLHLQ----ALGIP- 115 VL L GP QL E+TL + + +V +NS + HL+ A G+ Sbjct: 66 VLNLRTAGQGPGQLQREVTLHLNPISSVHIHHKSVVFLLNSPHPLVWHLKTERLATGVSR 125 Query: 116 LHLAYNSSLVTFQEPPGVNT--TELPSFP--KTQILEWAA-ERGPITSAAELNDPQSILL 170 L L S+V F T TE +FP +L WA E G +TS EL ++I + Sbjct: 126 LFLVSEGSVVQFSSANFSLTAETEERNFPHGNEHLLNWARKEYGAVTSFTELKIARNIYI 185 Query: 171 RLGQAQGSLSFCMLEAS-QDMGRTLEWRPRTPALVRGCHLEGVAGHKEAHILRVLPGHSA 229 ++G+ Q C + + + E+ P GC + ++E HI+ ++ +S Sbjct: 186 KVGEDQVFPPKCNIGKNFLSLNYLAEYLQ--PKAAEGCVMSSQPQNEEVHIIELITPNSN 243 Query: 230 GPRTVTVKVELSCAPGDLD------AVLILQGPPYVSWLI---DANHNMQIWTTGEYSFK 280 V + + P D +LIL+ V+W+I D +++I F Sbjct: 244 PYSAFQVDITIDIRPSQEDLEVVKNLILILKCKKSVNWVIKSFDVKGSLKIIAPNSIGFG 303 Query: 281 IFPEKNIRGFK-----LPDTPQGLLGEARMLNASIVASFVELPLASIVSLHASSCGGRLQ 335 E+++ K +P T L+ A S + S+ P+A+ H + Sbjct: 304 KESERSMTMTKSIRDDIPSTQGNLVKWALDNGYSPITSYTMAPVAN--RFHLRLENNAEE 361 Query: 336 TSPAPIQTTPPK 347 + T PP+ Sbjct: 362 MGDEEVHTIPPE 373 Score = 51.2 bits (121), Expect = 3e-06 Identities = 28/47 (59%), Positives = 31/47 (65%), Gaps = 4/47 (8%) Query: 573 NIISPDLSGCTSKGLVLPAVLGITFGAFLIGALLTAALWYIYSHTRE 619 N ISP + GL V+GI F AF+IGALLT ALWYIYSHT E Sbjct: 772 NPISPPIF----HGLDTLTVMGIAFAAFVIGALLTGALWYIYSHTGE 814 Score = 35.8 bits (81), Expect = 0.12 Identities = 19/77 (24%), Positives = 35/77 (45%) Query: 359 IQTKCADDAMTLVLKKELVAHLKCTITGLTFWDPSCEAEDRGDKFVLRSAYSSCGMQVSA 418 + KC ++ M + ++K+ + +T DP+C+A+ G FVL S + CG + Sbjct: 452 LSVKCDNEKMIVAVEKDSFQASGYSGMDVTLLDPTCKAKMNGTHFVLESPLNGCGTRPRW 511 Query: 419 SMISNEAVVNILSSSSP 435 S + N + P Sbjct: 512 SALDGVVYYNSIVIQVP 528 >gi|226371775 sex hormone-binding globulin isoform 2 precursor [Homo sapiens] Length = 384 Score = 33.1 bits (74), Expect = 0.79 Identities = 36/121 (29%), Positives = 46/121 (38%), Gaps = 23/121 (19%) Query: 65 HVLFLEFPTGPSQLELTLQASKQNGTWPREVLLVLSVNSSVFLHLQ-ALGIPLHLAYNSS 123 H+L L P PS L L LQ K +VLS S L L LG+PL L + S Sbjct: 246 HLLALGTPENPSWLSLHLQDQK----------VVLSSGSGPGLDLPLVLGLPLQLKLSMS 295 Query: 124 LVTFQEPPGVNTTELPSFPKTQILE-WAAERGPITSAAELNDPQSILLRLGQAQGSLSFC 182 V + + LP +L WA +G + A L S SFC Sbjct: 296 RVVLSQGSKMKALALPPLGLAPLLNLWAKPQGRLFLGA-----------LPGEDSSTSFC 344 Query: 183 M 183 + Sbjct: 345 L 345 >gi|7382460 sex hormone-binding globulin isoform 1 precursor [Homo sapiens] Length = 402 Score = 33.1 bits (74), Expect = 0.79 Identities = 36/121 (29%), Positives = 46/121 (38%), Gaps = 23/121 (19%) Query: 65 HVLFLEFPTGPSQLELTLQASKQNGTWPREVLLVLSVNSSVFLHLQ-ALGIPLHLAYNSS 123 H+L L P PS L L LQ K +VLS S L L LG+PL L + S Sbjct: 264 HLLALGTPENPSWLSLHLQDQK----------VVLSSGSGPGLDLPLVLGLPLQLKLSMS 313 Query: 124 LVTFQEPPGVNTTELPSFPKTQILE-WAAERGPITSAAELNDPQSILLRLGQAQGSLSFC 182 V + + LP +L WA +G + A L S SFC Sbjct: 314 RVVLSQGSKMKALALPPLGLAPLLNLWAKPQGRLFLGA-----------LPGEDSSTSFC 362 Query: 183 M 183 + Sbjct: 363 L 363 >gi|148746189 multiple PDZ domain protein [Homo sapiens] Length = 2041 Score = 32.3 bits (72), Expect = 1.3 Identities = 21/45 (46%), Positives = 28/45 (62%), Gaps = 7/45 (15%) Query: 320 ASIVSLHASSCGGRLQTSPAPIQTTPPKD----TCSP--ELLMSL 358 ASI+SLH SSCG L + + ++PPKD +C P +L MSL Sbjct: 857 ASILSLHGSSCGDGLNYG-SSLPSSPPKDVIENSCDPVLDLHMSL 900 >gi|239748362 PREDICTED: hypothetical protein XP_002346639 [Homo sapiens] Length = 165 Score = 30.8 bits (68), Expect = 3.9 Identities = 17/35 (48%), Positives = 21/35 (60%), Gaps = 4/35 (11%) Query: 224 LPGHSAGPRTVTVKVELSCAPGDLDAVLILQGPPY 258 L G AGPRT T L GD+DA L++QGP + Sbjct: 122 LHGPGAGPRTPTCHKLL----GDMDAALLVQGPHF 152 >gi|27734871 regulatory factor X, 6 [Homo sapiens] Length = 928 Score = 30.4 bits (67), Expect = 5.1 Identities = 33/112 (29%), Positives = 49/112 (43%), Gaps = 17/112 (15%) Query: 266 NHNMQIWTTGEYSF-KIFPEKNIRGFKL-PDTPQGLLGE----------ARMLN--ASIV 311 +HNMQ TG ++F + +G L P++P G G M+N S++ Sbjct: 766 SHNMQFLNTGSFNFLSNTGAASCQGATLPPNSPNGYYGSNINYPESHRLGSMVNQHVSVI 825 Query: 312 ASFVELPLASIV--SLHASSCGGRLQTSPAPIQTTPPKDTCSPELLMSLIQT 361 +S LP S + L+ GR QTS T+ P C +L S +QT Sbjct: 826 SSIRSLPPYSDIHDPLNILDDSGRKQTSSFYTDTSSPV-ACRTPVLASSLQT 876 >gi|197245373 proline rich 22 isoform 1 [Homo sapiens] Length = 422 Score = 30.0 bits (66), Expect = 6.7 Identities = 17/47 (36%), Positives = 24/47 (51%), Gaps = 12/47 (25%) Query: 312 ASFVELPLASIVSLHASSCGGRLQTSPAPIQTTPPKDTCSPELLMSL 358 A+FVELPL L+ PAP+ PPK+ P +L++L Sbjct: 166 AAFVELPLPP------------LEEGPAPLPPPPPKENKPPPVLITL 200 >gi|23503299 proline rich 22 isoform 2 [Homo sapiens] Length = 420 Score = 30.0 bits (66), Expect = 6.7 Identities = 17/47 (36%), Positives = 24/47 (51%), Gaps = 12/47 (25%) Query: 312 ASFVELPLASIVSLHASSCGGRLQTSPAPIQTTPPKDTCSPELLMSL 358 A+FVELPL L+ PAP+ PPK+ P +L++L Sbjct: 164 AAFVELPLPP------------LEEGPAPLPPPPPKENKPPPVLITL 198 >gi|239749012 PREDICTED: hypothetical protein XP_002346880 [Homo sapiens] Length = 414 Score = 30.0 bits (66), Expect = 6.7 Identities = 12/46 (26%), Positives = 28/46 (60%) Query: 421 ISNEAVVNILSSSSPQRKKVHCLNMDSLSFQLGLYLSPHFLQASNT 466 + +++++++ + P+R KV CLN + + LYL + L+ S++ Sbjct: 152 LRHQSLIDLRNHFCPRRSKVECLNFERTIIRPTLYLQVYVLKKSSS 197 >gi|239750729 PREDICTED: hypothetical protein XP_002347517 [Homo sapiens] Length = 263 Score = 29.6 bits (65), Expect = 8.7 Identities = 27/103 (26%), Positives = 40/103 (38%), Gaps = 9/103 (8%) Query: 285 KNIRGFKLPDTPQGLLGEARMLNASIVASFVELPLASIVSLHASSCGGRLQTSPAPIQTT 344 +N+ P + Q G+ ++ + + P V+ H Q P Sbjct: 134 QNVTARNFPPS-QDASGDLYTTSSQLTLPATQCPDGKSVTCHVKHYTNPSQDVTVPCPVP 192 Query: 345 PPKDTCSPELLMSLIQTKCADDAMTLVLKKELVAHLKCTITGL 387 PP C P L SL + D L+L E A+L CT+TGL Sbjct: 193 PPPPCCHPRL--SLHRPALED----LLLSSE--ANLTCTLTGL 227 >gi|7662346 ADNP homeobox 2 [Homo sapiens] Length = 1131 Score = 29.6 bits (65), Expect = 8.7 Identities = 26/100 (26%), Positives = 41/100 (41%), Gaps = 23/100 (23%) Query: 45 TTSQVSKGCVAQAPNAILEVHVLFLEFPTGPSQLELTLQASKQNGTWPREVLLVLSVNSS 104 T +Q + G + +P A + H+ + P Q LTLQ P+ V L Sbjct: 310 TVAQGAPGSLTHSPPAAGQSHMTLVSSPLPVGQNSLTLQPPA-----PQPVFL------- 357 Query: 105 VFLHLQALGIPLHLAYNSSLVTFQEPPG-----VNTTELP 139 + G+PLH + N ++ +P G V T+ LP Sbjct: 358 ------SHGVPLHQSVNPPVLPLSQPVGPVNKSVGTSVLP 391 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.319 0.134 0.404 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 26,268,139 Number of Sequences: 37866 Number of extensions: 1231515 Number of successful extensions: 2740 Number of sequences better than 10.0: 13 Number of HSP's better than 10.0 without gapping: 4 Number of HSP's successfully gapped in prelim test: 9 Number of HSP's that attempted gapping in prelim test: 2731 Number of HSP's gapped (non-prelim): 17 length of query: 625 length of database: 18,247,518 effective HSP length: 108 effective length of query: 517 effective length of database: 14,157,990 effective search space: 7319680830 effective search space used: 7319680830 T: 11 A: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.