Guide to the Human Genome
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Search of human proteins with 4557367

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|4557367 bleomycin hydrolase [Homo sapiens]
         (455 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|4557367 bleomycin hydrolase [Homo sapiens]                         946   0.0  
gi|4503151 cathepsin K preproprotein [Homo sapiens]                    33   0.53 
gi|6042196 cathepsin F [Homo sapiens]                                  32   1.2  
gi|123173752 synaptotagmin XIV-like [Homo sapiens]                     31   2.7  
gi|27894376 cell adhesion molecule with homology to L1CAM precur...    30   3.5  
gi|22202619 cathepsin L1 preproprotein [Homo sapiens]                  30   5.9  
gi|4503155 cathepsin L1 preproprotein [Homo sapiens]                   30   5.9  
gi|23110962 cathepsin S preproprotein [Homo sapiens]                   30   5.9  
gi|169207319 PREDICTED: hypothetical protein [Homo sapiens]            29   7.7  
gi|169207756 PREDICTED: hypothetical protein [Homo sapiens]            29   7.7  
gi|169207046 PREDICTED: hypothetical protein [Homo sapiens]            29   7.7  

>gi|4557367 bleomycin hydrolase [Homo sapiens]
          Length = 455

 Score =  946 bits (2445), Expect = 0.0
 Identities = 455/455 (100%), Positives = 455/455 (100%)

Query: 1   MSSSGLNSEKVAALIQKLNSDPQFVLAQNVGTTHDLLDICLKRATVQRAQHVFQHAVPQE 60
           MSSSGLNSEKVAALIQKLNSDPQFVLAQNVGTTHDLLDICLKRATVQRAQHVFQHAVPQE
Sbjct: 1   MSSSGLNSEKVAALIQKLNSDPQFVLAQNVGTTHDLLDICLKRATVQRAQHVFQHAVPQE 60

Query: 61  GKPITNQKSSGRCWIFSCLNVMRLPFMKKLNIEEFEFSQSYLFFWDKVERCYFFLSAFVD 120
           GKPITNQKSSGRCWIFSCLNVMRLPFMKKLNIEEFEFSQSYLFFWDKVERCYFFLSAFVD
Sbjct: 61  GKPITNQKSSGRCWIFSCLNVMRLPFMKKLNIEEFEFSQSYLFFWDKVERCYFFLSAFVD 120

Query: 121 TAQRKEPEDGRLVQFLLMNPANDGGQWDMLVNIVEKYGVIPKKCFPESYTTEATRRMNDI 180
           TAQRKEPEDGRLVQFLLMNPANDGGQWDMLVNIVEKYGVIPKKCFPESYTTEATRRMNDI
Sbjct: 121 TAQRKEPEDGRLVQFLLMNPANDGGQWDMLVNIVEKYGVIPKKCFPESYTTEATRRMNDI 180

Query: 181 LNHKMREFCIRLRNLVHSGATKGEISATQDVMMEEIFRVVCICLGNPPETFTWEYRDKDK 240
           LNHKMREFCIRLRNLVHSGATKGEISATQDVMMEEIFRVVCICLGNPPETFTWEYRDKDK
Sbjct: 181 LNHKMREFCIRLRNLVHSGATKGEISATQDVMMEEIFRVVCICLGNPPETFTWEYRDKDK 240

Query: 241 NYQKIGPITPLEFYREHVKPLFNMEDKICLVNDPRPQHKYNKLYTVEYLSNMVGGRKTLY 300
           NYQKIGPITPLEFYREHVKPLFNMEDKICLVNDPRPQHKYNKLYTVEYLSNMVGGRKTLY
Sbjct: 241 NYQKIGPITPLEFYREHVKPLFNMEDKICLVNDPRPQHKYNKLYTVEYLSNMVGGRKTLY 300

Query: 301 NNQPIDFLKKMVAASIKDGEAVWFGCDVGKHFNSKLGLSDMNLYDHELVFGVSLKNMNKA 360
           NNQPIDFLKKMVAASIKDGEAVWFGCDVGKHFNSKLGLSDMNLYDHELVFGVSLKNMNKA
Sbjct: 301 NNQPIDFLKKMVAASIKDGEAVWFGCDVGKHFNSKLGLSDMNLYDHELVFGVSLKNMNKA 360

Query: 361 ERLTFGESLMTHAMTFTAVSEKDDQDGAFTKWRVENSWGEDHGHKGYLCMTDEWFSEYVY 420
           ERLTFGESLMTHAMTFTAVSEKDDQDGAFTKWRVENSWGEDHGHKGYLCMTDEWFSEYVY
Sbjct: 361 ERLTFGESLMTHAMTFTAVSEKDDQDGAFTKWRVENSWGEDHGHKGYLCMTDEWFSEYVY 420

Query: 421 EVVVDRKHVPEEVLAVLEQEPIILPAWDPMGALAE 455
           EVVVDRKHVPEEVLAVLEQEPIILPAWDPMGALAE
Sbjct: 421 EVVVDRKHVPEEVLAVLEQEPIILPAWDPMGALAE 455


>gi|4503151 cathepsin K preproprotein [Homo sapiens]
          Length = 329

 Score = 33.1 bits (74), Expect = 0.53
 Identities = 11/19 (57%), Positives = 16/19 (84%)

Query: 392 WRVENSWGEDHGHKGYLCM 410
           W ++NSWGE+ G+KGY+ M
Sbjct: 292 WIIKNSWGENWGNKGYILM 310


>gi|6042196 cathepsin F [Homo sapiens]
          Length = 484

 Score = 32.0 bits (71), Expect = 1.2
 Identities = 14/39 (35%), Positives = 19/39 (48%), Gaps = 4/39 (10%)

Query: 369 LMTHAMTFTAVSEKDDQDGAFTKWRVENSWGEDHGHKGY 407
           L+ HA+       + D       W ++NSWG D G KGY
Sbjct: 428 LIDHAVLLVGYGNRSD----VPFWAIKNSWGTDWGEKGY 462


>gi|123173752 synaptotagmin XIV-like [Homo sapiens]
          Length = 645

 Score = 30.8 bits (68), Expect = 2.7
 Identities = 19/48 (39%), Positives = 25/48 (52%), Gaps = 1/48 (2%)

Query: 355 KNMNKAERLTFGESLMTHAMTFTAVSEKDDQDGAFTKWRVEN-SWGED 401
           K     ++  F  SL+TH    T VS  +D DGA  +   EN S+GED
Sbjct: 217 KQTGLEQKPKFSRSLLTHGEDGTEVSACEDLDGASQRRYSENLSYGED 264


>gi|27894376 cell adhesion molecule with homology to L1CAM precursor
           [Homo sapiens]
          Length = 1224

 Score = 30.4 bits (67), Expect = 3.5
 Identities = 39/182 (21%), Positives = 73/182 (40%), Gaps = 40/182 (21%)

Query: 214 EEIFRVVCICLGNPPETFTWEYRDKDKNYQKIGPITPLEFYREHVKPLFNMEDKICLVND 273
           +E F++ C   GNP  TF+W    KD N        P  F    + P  N      + N+
Sbjct: 50  DEYFQIECEAKGNPEPTFSW---TKDGN--------PFYFTDHRIIP-SNNSGTFRIPNE 97

Query: 274 PRPQHKYNKLYTVEYLSNMVGGRKTLYNNQPIDFL---------KKMVAASIKDGEAVWF 324
               H   K     + SN +G    +  ++ I+F+         +K+    +++G+ +  
Sbjct: 98  GHISHFQGKYRC--FASNKLG----IAMSEEIEFIVPSVPKFPKEKIDPLEVEEGDPIVL 151

Query: 325 GCDVGKHFNSKLGLSDMNLYDHELVFGVSLKNMNKAERLTFGESLMTHAMTFTAVSEKDD 384
            C      N   GL  +++Y       + L+++ + ER+   +      + F  V EKD 
Sbjct: 152 PC------NPPKGLPPLHIY----WMNIELEHIEQDERVYMSQK---GDLYFANVEEKDS 198

Query: 385 QD 386
           ++
Sbjct: 199 RN 200


>gi|22202619 cathepsin L1 preproprotein [Homo sapiens]
          Length = 333

 Score = 29.6 bits (65), Expect = 5.9
 Identities = 11/22 (50%), Positives = 15/22 (68%)

Query: 392 WRVENSWGEDHGHKGYLCMTDE 413
           W V+NSWGE+ G  GY+ M  +
Sbjct: 296 WLVKNSWGEEWGMGGYVKMAKD 317


>gi|4503155 cathepsin L1 preproprotein [Homo sapiens]
          Length = 333

 Score = 29.6 bits (65), Expect = 5.9
 Identities = 11/22 (50%), Positives = 15/22 (68%)

Query: 392 WRVENSWGEDHGHKGYLCMTDE 413
           W V+NSWGE+ G  GY+ M  +
Sbjct: 296 WLVKNSWGEEWGMGGYVKMAKD 317


>gi|23110962 cathepsin S preproprotein [Homo sapiens]
          Length = 331

 Score = 29.6 bits (65), Expect = 5.9
 Identities = 10/19 (52%), Positives = 14/19 (73%)

Query: 392 WRVENSWGEDHGHKGYLCM 410
           W V+NSWG + G +GY+ M
Sbjct: 294 WLVKNSWGHNFGEEGYIRM 312


>gi|169207319 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 828

 Score = 29.3 bits (64), Expect = 7.7
 Identities = 29/131 (22%), Positives = 63/131 (48%), Gaps = 9/131 (6%)

Query: 147 WDMLVNIVEKYGVI--PKKCFPESYTTEATRRMNDILNHKMREFCIRLRNLVHS-GATKG 203
           W+  V+ ++K   I   K CF     T+   +++DI N +  EF  +++ LV +  A + 
Sbjct: 300 WEQEVSELKKDLAILEAKLCF----FTDNKEKLDDISNDEKNEFLNKIKQLVETLHAARM 355

Query: 204 EISATQDVMMEEIFRVVCICLGNPPETFTWEYRDKDKNYQKIGPITPLEFYREHVK-PLF 262
           E    ++  M+ + R   I L    + F  + +  D+N +++  I+  E++    +  + 
Sbjct: 356 EYKDLRE-KMKTLARQYKIVLSEEEKAFLQKQKIHDENQKQLTFISQKEYFLSQKRVDIK 414

Query: 263 NMEDKICLVND 273
           NME+ +  + +
Sbjct: 415 NMEEGLITLQE 425


>gi|169207756 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 828

 Score = 29.3 bits (64), Expect = 7.7
 Identities = 29/131 (22%), Positives = 63/131 (48%), Gaps = 9/131 (6%)

Query: 147 WDMLVNIVEKYGVI--PKKCFPESYTTEATRRMNDILNHKMREFCIRLRNLVHS-GATKG 203
           W+  V+ ++K   I   K CF     T+   +++DI N +  EF  +++ LV +  A + 
Sbjct: 300 WEQEVSELKKDLAILEAKLCF----FTDNKEKLDDISNDEKNEFLNKIKQLVETLHAARM 355

Query: 204 EISATQDVMMEEIFRVVCICLGNPPETFTWEYRDKDKNYQKIGPITPLEFYREHVK-PLF 262
           E    ++  M+ + R   I L    + F  + +  D+N +++  I+  E++    +  + 
Sbjct: 356 EYKDLRE-KMKTLARQYKIVLSEEEKAFLQKQKIHDENQKQLTFISQKEYFLSQKRVDIK 414

Query: 263 NMEDKICLVND 273
           NME+ +  + +
Sbjct: 415 NMEEGLITLQE 425


>gi|169207046 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 828

 Score = 29.3 bits (64), Expect = 7.7
 Identities = 29/131 (22%), Positives = 63/131 (48%), Gaps = 9/131 (6%)

Query: 147 WDMLVNIVEKYGVI--PKKCFPESYTTEATRRMNDILNHKMREFCIRLRNLVHS-GATKG 203
           W+  V+ ++K   I   K CF     T+   +++DI N +  EF  +++ LV +  A + 
Sbjct: 300 WEQEVSELKKDLAILEAKLCF----FTDNKEKLDDISNDEKNEFLNKIKQLVETLHAARM 355

Query: 204 EISATQDVMMEEIFRVVCICLGNPPETFTWEYRDKDKNYQKIGPITPLEFYREHVK-PLF 262
           E    ++  M+ + R   I L    + F  + +  D+N +++  I+  E++    +  + 
Sbjct: 356 EYKDLRE-KMKTLARQYKIVLSEEEKAFLQKQKIHDENQKQLTFISQKEYFLSQKRVDIK 414

Query: 263 NMEDKICLVND 273
           NME+ +  + +
Sbjct: 415 NMEEGLITLQE 425


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.321    0.136    0.423 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 17,454,848
Number of Sequences: 37866
Number of extensions: 768133
Number of successful extensions: 1471
Number of sequences better than 10.0: 11
Number of HSP's better than 10.0 without gapping: 6
Number of HSP's successfully gapped in prelim test: 5
Number of HSP's that attempted gapping in prelim test: 1460
Number of HSP's gapped (non-prelim): 16
length of query: 455
length of database: 18,247,518
effective HSP length: 106
effective length of query: 349
effective length of database: 14,233,722
effective search space: 4967568978
effective search space used: 4967568978
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 64 (29.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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