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Search of human proteins with 45267837
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|45267837 rabphilin 3A homolog isoform 2 [Homo sapiens]
(690 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|45267837 rabphilin 3A homolog isoform 2 [Homo sapiens] 1430 0.0
gi|219804203 rabphilin 3A homolog isoform 1 [Homo sapiens] 1422 0.0
gi|6005997 double C2-like domains, beta [Homo sapiens] 490 e-138
gi|47078261 double C2-like domains, alpha [Homo sapiens] 421 e-117
gi|239744413 PREDICTED: hypothetical protein LOC390213 [Homo sap... 322 7e-88
gi|5902064 rabphilin 3A-like (without C2 domains) [Homo sapiens] 216 6e-56
gi|169202933 PREDICTED: similar to hCG21066 [Homo sapiens] 197 4e-50
gi|169203543 PREDICTED: similar to hCG21066 [Homo sapiens] 197 4e-50
gi|193804862 synaptotagmin-like 4 [Homo sapiens] 173 5e-43
gi|193804860 synaptotagmin-like 4 [Homo sapiens] 173 5e-43
gi|38570146 synaptotagmin VII [Homo sapiens] 172 9e-43
gi|211059429 synaptotagmin II [Homo sapiens] 169 1e-41
gi|31543670 synaptotagmin II [Homo sapiens] 169 1e-41
gi|209447073 synaptotagmin I [Homo sapiens] 167 2e-41
gi|5032139 synaptotagmin I [Homo sapiens] 167 2e-41
gi|209447070 synaptotagmin I [Homo sapiens] 167 2e-41
gi|45504376 synaptotagmin VI [Homo sapiens] 167 4e-41
gi|238550198 synaptotagmin III [Homo sapiens] 165 1e-40
gi|238550196 synaptotagmin III [Homo sapiens] 165 1e-40
gi|14150054 synaptotagmin III [Homo sapiens] 165 1e-40
gi|39752671 synaptotagmin X [Homo sapiens] 159 6e-39
gi|92859638 synaptotagmin V [Homo sapiens] 155 2e-37
gi|24308219 synaptotagmin IV [Homo sapiens] 148 1e-35
gi|28376627 synaptotagmin IX [Homo sapiens] 144 2e-34
gi|216548478 synaptotagmin XI [Homo sapiens] 138 2e-32
gi|40068038 B/K protein [Homo sapiens] 116 8e-26
gi|244790020 synaptotagmin-like 2 isoform i [Homo sapiens] 114 2e-25
gi|244790013 synaptotagmin-like 2 isoform g [Homo sapiens] 114 2e-25
gi|15011900 synaptotagmin-like 2 isoform b [Homo sapiens] 107 3e-23
gi|15011902 synaptotagmin-like 2 isoform a [Homo sapiens] 107 3e-23
>gi|45267837 rabphilin 3A homolog isoform 2 [Homo sapiens]
Length = 690
Score = 1430 bits (3701), Expect = 0.0
Identities = 690/690 (100%), Positives = 690/690 (100%)
Query: 1 MTDTVFSNSSNRWMYPSDRPLQSKLQAGWSVHPGGQPDRQRKQEELTDEEKEIINRVIAR 60
MTDTVFSNSSNRWMYPSDRPLQSKLQAGWSVHPGGQPDRQRKQEELTDEEKEIINRVIAR
Sbjct: 1 MTDTVFSNSSNRWMYPSDRPLQSKLQAGWSVHPGGQPDRQRKQEELTDEEKEIINRVIAR 60
Query: 61 AEKMEEMEQERIGRLVDRLENMRKNVAGDGVNRCILCGEQLGMLGSACVVCEDCKKNVCT 120
AEKMEEMEQERIGRLVDRLENMRKNVAGDGVNRCILCGEQLGMLGSACVVCEDCKKNVCT
Sbjct: 61 AEKMEEMEQERIGRLVDRLENMRKNVAGDGVNRCILCGEQLGMLGSACVVCEDCKKNVCT 120
Query: 121 KCGVETNNRLHSVWLCKICIEQREVWKRSGAWFFKGFPKQVLPQPMPIKKTKPQQPVSEP 180
KCGVETNNRLHSVWLCKICIEQREVWKRSGAWFFKGFPKQVLPQPMPIKKTKPQQPVSEP
Sbjct: 121 KCGVETNNRLHSVWLCKICIEQREVWKRSGAWFFKGFPKQVLPQPMPIKKTKPQQPVSEP 180
Query: 181 AAPEQPAPEPKHPARAPARGDSEDRRGPGQKTGPDPASAPGRGNYGPPVRRASEARMSSS 240
AAPEQPAPEPKHPARAPARGDSEDRRGPGQKTGPDPASAPGRGNYGPPVRRASEARMSSS
Sbjct: 181 AAPEQPAPEPKHPARAPARGDSEDRRGPGQKTGPDPASAPGRGNYGPPVRRASEARMSSS 240
Query: 241 SRDSESWDHSGGAGDSSRSPAGLRRANSVQASRPAPGSVQSPAPPQPGQPGTPGGSRPGP 300
SRDSESWDHSGGAGDSSRSPAGLRRANSVQASRPAPGSVQSPAPPQPGQPGTPGGSRPGP
Sbjct: 241 SRDSESWDHSGGAGDSSRSPAGLRRANSVQASRPAPGSVQSPAPPQPGQPGTPGGSRPGP 300
Query: 301 GPAGRFPDQKPEVAPSDPGTTAPPREERTGGVGGYPAVGAREDRMSHPSGPYSQASAAAP 360
GPAGRFPDQKPEVAPSDPGTTAPPREERTGGVGGYPAVGAREDRMSHPSGPYSQASAAAP
Sbjct: 301 GPAGRFPDQKPEVAPSDPGTTAPPREERTGGVGGYPAVGAREDRMSHPSGPYSQASAAAP 360
Query: 361 QPAAARQPPPPEEEEEEANSYDSDEATTLGALEFSLLYDQDNSSLQCTIIKAKGLKPMDS 420
QPAAARQPPPPEEEEEEANSYDSDEATTLGALEFSLLYDQDNSSLQCTIIKAKGLKPMDS
Sbjct: 361 QPAAARQPPPPEEEEEEANSYDSDEATTLGALEFSLLYDQDNSSLQCTIIKAKGLKPMDS 420
Query: 421 NGLADPYVKLHLLPGASKSNKLRTKTLRNTRNPIWNETLVYHGITDEDMQRKTLRISVCD 480
NGLADPYVKLHLLPGASKSNKLRTKTLRNTRNPIWNETLVYHGITDEDMQRKTLRISVCD
Sbjct: 421 NGLADPYVKLHLLPGASKSNKLRTKTLRNTRNPIWNETLVYHGITDEDMQRKTLRISVCD 480
Query: 481 EDKFGHNEFIGETRFSLKKLKPNQRKNFNICLERVIPMKRAGTTGSARGMALYEEEQVER 540
EDKFGHNEFIGETRFSLKKLKPNQRKNFNICLERVIPMKRAGTTGSARGMALYEEEQVER
Sbjct: 481 EDKFGHNEFIGETRFSLKKLKPNQRKNFNICLERVIPMKRAGTTGSARGMALYEEEQVER 540
Query: 541 VGDIEERGKILVSLMYSTQQGGLIVGIIRCVHLAAMDANGYSDPFVKLWLKPDMGKKAKH 600
VGDIEERGKILVSLMYSTQQGGLIVGIIRCVHLAAMDANGYSDPFVKLWLKPDMGKKAKH
Sbjct: 541 VGDIEERGKILVSLMYSTQQGGLIVGIIRCVHLAAMDANGYSDPFVKLWLKPDMGKKAKH 600
Query: 601 KTQIKKKTLNPEFNEEFFYDIKHSDLAKKSLDISVWDYDIGKSNDYIGGCQLGISAKGER 660
KTQIKKKTLNPEFNEEFFYDIKHSDLAKKSLDISVWDYDIGKSNDYIGGCQLGISAKGER
Sbjct: 601 KTQIKKKTLNPEFNEEFFYDIKHSDLAKKSLDISVWDYDIGKSNDYIGGCQLGISAKGER 660
Query: 661 LKHWYECLKNKDKKIERWHQLQNENHVSSD 690
LKHWYECLKNKDKKIERWHQLQNENHVSSD
Sbjct: 661 LKHWYECLKNKDKKIERWHQLQNENHVSSD 690
>gi|219804203 rabphilin 3A homolog isoform 1 [Homo sapiens]
Length = 694
Score = 1422 bits (3682), Expect = 0.0
Identities = 689/694 (99%), Positives = 690/694 (99%), Gaps = 4/694 (0%)
Query: 1 MTDTVFSNSSNRWMYPSDRPLQS----KLQAGWSVHPGGQPDRQRKQEELTDEEKEIINR 56
MTDTVFSNSSNRWMYPSDRPLQS +LQAGWSVHPGGQPDRQRKQEELTDEEKEIINR
Sbjct: 1 MTDTVFSNSSNRWMYPSDRPLQSNDKEQLQAGWSVHPGGQPDRQRKQEELTDEEKEIINR 60
Query: 57 VIARAEKMEEMEQERIGRLVDRLENMRKNVAGDGVNRCILCGEQLGMLGSACVVCEDCKK 116
VIARAEKMEEMEQERIGRLVDRLENMRKNVAGDGVNRCILCGEQLGMLGSACVVCEDCKK
Sbjct: 61 VIARAEKMEEMEQERIGRLVDRLENMRKNVAGDGVNRCILCGEQLGMLGSACVVCEDCKK 120
Query: 117 NVCTKCGVETNNRLHSVWLCKICIEQREVWKRSGAWFFKGFPKQVLPQPMPIKKTKPQQP 176
NVCTKCGVETNNRLHSVWLCKICIEQREVWKRSGAWFFKGFPKQVLPQPMPIKKTKPQQP
Sbjct: 121 NVCTKCGVETNNRLHSVWLCKICIEQREVWKRSGAWFFKGFPKQVLPQPMPIKKTKPQQP 180
Query: 177 VSEPAAPEQPAPEPKHPARAPARGDSEDRRGPGQKTGPDPASAPGRGNYGPPVRRASEAR 236
VSEPAAPEQPAPEPKHPARAPARGDSEDRRGPGQKTGPDPASAPGRGNYGPPVRRASEAR
Sbjct: 181 VSEPAAPEQPAPEPKHPARAPARGDSEDRRGPGQKTGPDPASAPGRGNYGPPVRRASEAR 240
Query: 237 MSSSSRDSESWDHSGGAGDSSRSPAGLRRANSVQASRPAPGSVQSPAPPQPGQPGTPGGS 296
MSSSSRDSESWDHSGGAGDSSRSPAGLRRANSVQASRPAPGSVQSPAPPQPGQPGTPGGS
Sbjct: 241 MSSSSRDSESWDHSGGAGDSSRSPAGLRRANSVQASRPAPGSVQSPAPPQPGQPGTPGGS 300
Query: 297 RPGPGPAGRFPDQKPEVAPSDPGTTAPPREERTGGVGGYPAVGAREDRMSHPSGPYSQAS 356
RPGPGPAGRFPDQKPEVAPSDPGTTAPPREERTGGVGGYPAVGAREDRMSHPSGPYSQAS
Sbjct: 301 RPGPGPAGRFPDQKPEVAPSDPGTTAPPREERTGGVGGYPAVGAREDRMSHPSGPYSQAS 360
Query: 357 AAAPQPAAARQPPPPEEEEEEANSYDSDEATTLGALEFSLLYDQDNSSLQCTIIKAKGLK 416
AAAPQPAAARQPPPPEEEEEEANSYDSDEATTLGALEFSLLYDQDNSSLQCTIIKAKGLK
Sbjct: 361 AAAPQPAAARQPPPPEEEEEEANSYDSDEATTLGALEFSLLYDQDNSSLQCTIIKAKGLK 420
Query: 417 PMDSNGLADPYVKLHLLPGASKSNKLRTKTLRNTRNPIWNETLVYHGITDEDMQRKTLRI 476
PMDSNGLADPYVKLHLLPGASKSNKLRTKTLRNTRNPIWNETLVYHGITDEDMQRKTLRI
Sbjct: 421 PMDSNGLADPYVKLHLLPGASKSNKLRTKTLRNTRNPIWNETLVYHGITDEDMQRKTLRI 480
Query: 477 SVCDEDKFGHNEFIGETRFSLKKLKPNQRKNFNICLERVIPMKRAGTTGSARGMALYEEE 536
SVCDEDKFGHNEFIGETRFSLKKLKPNQRKNFNICLERVIPMKRAGTTGSARGMALYEEE
Sbjct: 481 SVCDEDKFGHNEFIGETRFSLKKLKPNQRKNFNICLERVIPMKRAGTTGSARGMALYEEE 540
Query: 537 QVERVGDIEERGKILVSLMYSTQQGGLIVGIIRCVHLAAMDANGYSDPFVKLWLKPDMGK 596
QVERVGDIEERGKILVSLMYSTQQGGLIVGIIRCVHLAAMDANGYSDPFVKLWLKPDMGK
Sbjct: 541 QVERVGDIEERGKILVSLMYSTQQGGLIVGIIRCVHLAAMDANGYSDPFVKLWLKPDMGK 600
Query: 597 KAKHKTQIKKKTLNPEFNEEFFYDIKHSDLAKKSLDISVWDYDIGKSNDYIGGCQLGISA 656
KAKHKTQIKKKTLNPEFNEEFFYDIKHSDLAKKSLDISVWDYDIGKSNDYIGGCQLGISA
Sbjct: 601 KAKHKTQIKKKTLNPEFNEEFFYDIKHSDLAKKSLDISVWDYDIGKSNDYIGGCQLGISA 660
Query: 657 KGERLKHWYECLKNKDKKIERWHQLQNENHVSSD 690
KGERLKHWYECLKNKDKKIERWHQLQNENHVSSD
Sbjct: 661 KGERLKHWYECLKNKDKKIERWHQLQNENHVSSD 694
>gi|6005997 double C2-like domains, beta [Homo sapiens]
Length = 412
Score = 490 bits (1262), Expect = e-138
Identities = 246/386 (63%), Positives = 290/386 (75%), Gaps = 25/386 (6%)
Query: 302 PAGRFPDQKPEVA-PSDPGTTAPPREERTGGVGGYPAVGAREDR--MSHPSGPYSQASAA 358
P G PD P A P D AP R G P+ GARED + G Y +
Sbjct: 41 PRGLPPDAGPRAAAPPD----APARPAVAGAGRRSPSDGAREDDEDVDQLFGAYGSSPGP 96
Query: 359 APQPAAARQPPPPEEEEEEANSYDSDEATTLGALEFSLLYDQDNSSLQCTIIKAKGLKPM 418
+P P+ AR P P E+E +A+ Y+SD+ T LG L+FSLLYDQ+N++L CTI KAKGLKPM
Sbjct: 97 SPGPSPARPPAKPPEDEPDADGYESDDCTALGTLDFSLLYDQENNALHCTITKAKGLKPM 156
Query: 419 DSNGLADPYVKLHLLPGASKSNKLRTKTLRNTRNPIWNETLVYHGITDEDMQRKTLRISV 478
D NGLADPYVKLHLLPGASK+NKLRTKTLRNT NP WNETL Y+GITDEDM RKTLRISV
Sbjct: 157 DHNGLADPYVKLHLLPGASKANKLRTKTLRNTLNPTWNETLTYYGITDEDMIRKTLRISV 216
Query: 479 CDEDKFGHNEFIGETRFSLKKLKPNQRKNFNICLERVIPMKRAGTTGSARGMALYEEEQV 538
CDEDKF HNEFIGETR LKKLKPN K FNICLE+ +P+ + E++
Sbjct: 217 CDEDKFRHNEFIGETRVPLKKLKPNHTKTFNICLEKQLPVDKT------------EDK-- 262
Query: 539 ERVGDIEERGKILVSLMYSTQQGGLIVGIIRCVHLAAMDANGYSDPFVKLWLKPDMGKKA 598
+EERG+IL+SL YS+Q+ GL+VGI+RC HLAAMDANGYSDP+VK +L+PD+ KK+
Sbjct: 263 ----SLEERGRILISLKYSSQKQGLLVGIVRCAHLAAMDANGYSDPYVKTYLRPDVDKKS 318
Query: 599 KHKTQIKKKTLNPEFNEEFFYDIKHSDLAKKSLDISVWDYDIGKSNDYIGGCQLGISAKG 658
KHKT +KKKTLNPEFNEEF Y+IKH DLAKKSL+++VWDYDIGKSND+IGG LGI AKG
Sbjct: 319 KHKTAVKKKTLNPEFNEEFCYEIKHGDLAKKSLEVTVWDYDIGKSNDFIGGVVLGIHAKG 378
Query: 659 ERLKHWYECLKNKDKKIERWHQLQNE 684
ERLKHW++CLKNKDK+IERWH L +E
Sbjct: 379 ERLKHWFDCLKNKDKRIERWHTLTSE 404
>gi|47078261 double C2-like domains, alpha [Homo sapiens]
Length = 400
Score = 421 bits (1081), Expect = e-117
Identities = 203/327 (62%), Positives = 256/327 (78%), Gaps = 4/327 (1%)
Query: 362 PAAARQPPPPEEEEEEANSYDSDEATTLGALEFSLLYDQDNSSLQCTIIKAKGLKPMDSN 421
P AA E+ E +SYDSD+AT LG LEF LLYD+ + +L C+I++AKGLKPMD N
Sbjct: 63 PPAALLGATTPEDGAEVDSYDSDDATALGTLEFDLLYDRASCTLHCSILRAKGLKPMDFN 122
Query: 422 GLADPYVKLHLLPGASKSNKLRTKTLRNTRNPIWNETLVYHGITDEDMQRKTLRISVCDE 481
GLADPYVKLHLLPGA K+NKL+TKT RNT NP+WNE L Y GITD+D+ K LRI+VCDE
Sbjct: 123 GLADPYVKLHLLPGACKANKLKTKTQRNTLNPVWNEDLTYSGITDDDITHKVLRIAVCDE 182
Query: 482 DKFGHNEFIGETRFSLKKLKPNQRKNFNICLERVIPMKRAGTTGSA-RGMALY--EEEQV 538
DK HNEFIGE R L++LKP+Q+K+FNICLER +P+ + +A RG++ Y E EQ
Sbjct: 183 DKLSHNEFIGEIRVPLRRLKPSQKKHFNICLERQVPLASPSSMSAALRGISCYLKELEQA 242
Query: 539 ER-VGDIEERGKILVSLMYSTQQGGLIVGIIRCVHLAAMDANGYSDPFVKLWLKPDMGKK 597
E+ G +EERG+IL+SL YS+++ GL+VGI+RC HLAAMD NGYSDP+VK +L+PD+ KK
Sbjct: 243 EQGQGLLEERGRILLSLSYSSRRRGLLVGILRCAHLAAMDVNGYSDPYVKTYLRPDVDKK 302
Query: 598 AKHKTQIKKKTLNPEFNEEFFYDIKHSDLAKKSLDISVWDYDIGKSNDYIGGCQLGISAK 657
+KHKT +KKKTLNPEFNEEFFY+I+ S LA K+L+++VWDYDIGKSND+IGG LG A+
Sbjct: 303 SKHKTCVKKKTLNPEFNEEFFYEIELSTLATKTLEVTVWDYDIGKSNDFIGGVSLGPGAR 362
Query: 658 GERLKHWYECLKNKDKKIERWHQLQNE 684
GE KHW +CL+ D +ERWH L +E
Sbjct: 363 GEARKHWSDCLQQPDAALERWHTLTSE 389
>gi|239744413 PREDICTED: hypothetical protein LOC390213 [Homo
sapiens]
Length = 431
Score = 322 bits (825), Expect = 7e-88
Identities = 187/432 (43%), Positives = 253/432 (58%), Gaps = 41/432 (9%)
Query: 269 VQASRPAPGSVQSPAPPQPGQPGTPGGSRPGPGPAGRFPDQKPEVAPSDPGTTAPPREER 328
V++ +P + P P G+ G R Q+ PG P R
Sbjct: 31 VRSRQPQSSGISLSLRPPPPVWVPMAGTAAAGGQPPRVSMQEHMAIDVSPGPIRPIRLIS 90
Query: 329 TGGVGGYPAVGAREDRMSHPSGPYSQASAAAPQPAAARQPPPPEEEEEEANSYDSDEATT 388
YP + HP P + +AA+ +A + P PE E DSD++T
Sbjct: 91 HYFPHFYPFA----EPALHP--PNLRPAAASAVRSAPQLQPDPEPEG------DSDDSTA 138
Query: 389 LGALEFSLLYDQDNSSLQCTIIKAKGLKPMDSNGLADPYVKLHLLPGASKSNKLRTKTLR 448
LG LEF+LL++ DNS+L CT +AKGLKP+ S G AD YVK +LLPGASK+++LRT T+R
Sbjct: 139 LGTLEFTLLFEADNSALHCTAHRAKGLKPLAS-GSADAYVKANLLPGASKASQLRTHTVR 197
Query: 449 NTRNPIWNETLVYHGITDEDMQRKTLRI------SVCDEDKFGHNEF----IGETRFSLK 498
TR P+W ETL YHG T +D + KTLR +VC ++ +GE R L+
Sbjct: 198 GTRVPVWEETLTYHGFTRQDAECKTLRSDLGGHQAVCVRGPMVQRQWQAPSLGELRVPLR 257
Query: 499 KLKPNQRKNFNICLERVIPMKRAGTTGSARGMALYEEEQVERVGDIEERGKILVSLMYST 558
KL PN+ ++F+ICLE+ E+VE EE G +L+SL YS+
Sbjct: 258 KLVPNRARSFDICLEK------------------RRLEEVETEVAWEECGHVLLSLCYSS 299
Query: 559 QQGGLIVGIIRCVHLAAMDANGYSDPFVKLWLKPDMGKKAKHKTQIKKKTLNPEFNEEFF 618
QQGGL+VG++RC HLA MDANGYSDPFV+L+L P+ GKK+K KT + +KTLNPEFNEEFF
Sbjct: 300 QQGGLLVGVLRCAHLAPMDANGYSDPFVRLFLHPNAGKKSKFKTSVHRKTLNPEFNEEFF 359
Query: 619 YDIKHSDLAKKSLDISVWDYDIGKSNDYIGGCQLGISAKGERLKHWYECLKNKDKKIERW 678
Y +LA+K+L +SVWDYD+G ++D+IGG QLG A GERL+HW ECL + D +++ W
Sbjct: 360 YSGPREELAQKTLLVSVWDYDLGTADDFIGGVQLGSHASGERLRHWLECLGHSDHRLKLW 419
Query: 679 HQLQNENHVSSD 690
H L ++ SD
Sbjct: 420 HPLDSKPVQLSD 431
>gi|5902064 rabphilin 3A-like (without C2 domains) [Homo sapiens]
Length = 315
Score = 216 bits (550), Expect = 6e-56
Identities = 131/336 (38%), Positives = 184/336 (54%), Gaps = 40/336 (11%)
Query: 1 MTDTVFSNSSNRWMYPSDRPL--QSKLQAGWSVHPGGQPDRQRKQEELTDEEKEIINRVI 58
M DT+F + +++W+ P+DR L ++KLQ GWSVH Q ++QR+++ L+ E E I +VI
Sbjct: 1 MADTIFGSGNDQWVCPNDRQLALRAKLQTGWSVHTY-QTEKQRRKQHLSPAEVEAILQVI 59
Query: 59 ARAEKMEEMEQERIGRLVDRLENMRKNVAGDGVNRCILCGEQLGMLGSACVVCEDCKKNV 118
RAE+++ +EQ+RIGRLV+RLE MR+NV G+G+++C+LCGE LG LGS+ V C+DC+K V
Sbjct: 60 QRAERLDVLEQQRIGRLVERLETMRRNVMGNGLSQCLLCGEVLGFLGSSSVFCKDCRKKV 119
Query: 119 CTKCGVETN-NRLHSVWLCKICIEQREVWKRSGAWFFKGFPKQVLPQPMPIKKTKPQ-QP 176
CTKCG+E + + +WLCKIC EQREVWKRSGAWF+KG PK +LP P + P +P
Sbjct: 120 CTKCGIEASPGQKRPLWLCKICSEQREVWKRSGAWFYKGLPKYILPLKTPGRADDPHFRP 179
Query: 177 VSEPAAPEQPAPEPKHPARAPARG-----DSEDRRGPGQKTGPDPASAPGRGNYGPPVRR 231
+ A +P ARG DS+ + D + G VR
Sbjct: 180 LPTEPAEREPRSSETSRIYTWARGRVVSSDSDSDSDLSSSSLEDRLPSTG-------VR- 231
Query: 232 ASEARMSSSSRDSESWDHSGGAGDSSR-----SPAGLRRANSVQAS-RPAPGSVQSPAPP 285
+ + W SGG+ ++ R P L S AS GS P P
Sbjct: 232 --------DRKGDKPWKESGGSVEAPRMGFTHPPGHLSGCQSSLASGETGTGSADPPGGP 283
Query: 286 QPG-QPGTPGGSRPGPGPAGRFPDQKPEVAPSDPGT 320
+PG P PG PA + AP+ P +
Sbjct: 284 RPGLTRRAPVKDTPGRAPAA-------DAAPAGPSS 312
>gi|169202933 PREDICTED: similar to hCG21066 [Homo sapiens]
Length = 451
Score = 197 bits (500), Expect = 4e-50
Identities = 95/165 (57%), Positives = 122/165 (73%), Gaps = 5/165 (3%)
Query: 526 SARGMALYEEEQVERVGDIEERGKILVSLMYSTQQGGLIVGIIRCVHLAAMDANGYSDPF 585
SAR M E+VE EE G +L+SL YS+QQGGL+VG++RC HLA MDANGYSDPF
Sbjct: 292 SARSM-----EEVETEVAWEECGHVLLSLCYSSQQGGLLVGVLRCAHLAPMDANGYSDPF 346
Query: 586 VKLWLKPDMGKKAKHKTQIKKKTLNPEFNEEFFYDIKHSDLAKKSLDISVWDYDIGKSND 645
V+L+L P+ GKK+K KT + +KTLNPEFNEEFFY +LA+K+L +SVWDYD+G ++D
Sbjct: 347 VRLFLHPNAGKKSKFKTSVHRKTLNPEFNEEFFYSGPREELAQKTLLVSVWDYDLGTADD 406
Query: 646 YIGGCQLGISAKGERLKHWYECLKNKDKKIERWHQLQNENHVSSD 690
+IGG QLG A GERL+HW ECL + D ++E WH L ++ SD
Sbjct: 407 FIGGVQLGSHASGERLRHWLECLGHSDHRLELWHPLDSKPVQLSD 451
Score = 154 bits (390), Expect = 2e-37
Identities = 91/198 (45%), Positives = 125/198 (63%), Gaps = 19/198 (9%)
Query: 347 HPSGPYSQASAAAPQPAAARQPPPPEEEEEEANSYDSDEATTLGALEFSLLYDQDNSSLQ 406
HP P + +AA+ +A + P PE E DSD++T LG LEF+LL++ DNS+L
Sbjct: 51 HP--PNLRPAAASAVRSAPQLQPDPEPEG------DSDDSTALGTLEFTLLFEADNSALH 102
Query: 407 CTIIKAKGLKPMDSNGLADPYVKLHLLPGASKSNKLRTKTLRNTRNPIWNETLVYHGITD 466
CT +AKGLKP+ S G AD YVK +LLPGASK+++LRT T+R TR P+W ETL YHG T
Sbjct: 103 CTAHRAKGLKPLAS-GSADAYVKANLLPGASKASQLRTHTVRGTRVPVWEETLTYHGFTR 161
Query: 467 EDMQRKTLRI------SVCDEDKFGHNEF----IGETRFSLKKLKPNQRKNFNICLERVI 516
+D + KTLR +VC ++ +GE R L+KL PN+ ++F+ICLE+
Sbjct: 162 QDAECKTLRSDLGGHQAVCVRGPMVQRQWQAPSLGELRVPLRKLVPNRARSFDICLEKRR 221
Query: 517 PMKRAGTTGSARGMALYE 534
KR + +A GM+LYE
Sbjct: 222 LAKRPKSLDTACGMSLYE 239
Score = 78.2 bits (191), Expect = 2e-14
Identities = 46/130 (35%), Positives = 66/130 (50%), Gaps = 5/130 (3%)
Query: 366 RQPPPPEEEEEEANSYDSDEATTL----GALEFSLLYDQDNSSLQCTIIKAKGLKPMDSN 421
R P P+ + A S + E G + SL Y L +++ L PMD+N
Sbjct: 281 RVPSAPDPKHNSARSMEEVETEVAWEECGHVLLSLCYSSQQGGLLVGVLRCAHLAPMDAN 340
Query: 422 GLADPYVKLHLLPGASKSNKLRTKTLRNTRNPIWNETLVYHGITDEDMQRKTLRISVCDE 481
G +DP+V+L L P A K +K +T R T NP +NE Y G E++ +KTL +SV D
Sbjct: 341 GYSDPFVRLFLHPNAGKKSKFKTSVHRKTLNPEFNEEFFYSG-PREELAQKTLLVSVWDY 399
Query: 482 DKFGHNEFIG 491
D ++FIG
Sbjct: 400 DLGTADDFIG 409
>gi|169203543 PREDICTED: similar to hCG21066 [Homo sapiens]
Length = 451
Score = 197 bits (500), Expect = 4e-50
Identities = 95/165 (57%), Positives = 122/165 (73%), Gaps = 5/165 (3%)
Query: 526 SARGMALYEEEQVERVGDIEERGKILVSLMYSTQQGGLIVGIIRCVHLAAMDANGYSDPF 585
SAR M E+VE EE G +L+SL YS+QQGGL+VG++RC HLA MDANGYSDPF
Sbjct: 292 SARSM-----EEVETEVAWEECGHVLLSLCYSSQQGGLLVGVLRCAHLAPMDANGYSDPF 346
Query: 586 VKLWLKPDMGKKAKHKTQIKKKTLNPEFNEEFFYDIKHSDLAKKSLDISVWDYDIGKSND 645
V+L+L P+ GKK+K KT + +KTLNPEFNEEFFY +LA+K+L +SVWDYD+G ++D
Sbjct: 347 VRLFLHPNAGKKSKFKTSVHRKTLNPEFNEEFFYSGPREELAQKTLLVSVWDYDLGTADD 406
Query: 646 YIGGCQLGISAKGERLKHWYECLKNKDKKIERWHQLQNENHVSSD 690
+IGG QLG A GERL+HW ECL + D ++E WH L ++ SD
Sbjct: 407 FIGGVQLGSHASGERLRHWLECLGHSDHRLELWHPLDSKPVQLSD 451
Score = 154 bits (390), Expect = 2e-37
Identities = 91/198 (45%), Positives = 125/198 (63%), Gaps = 19/198 (9%)
Query: 347 HPSGPYSQASAAAPQPAAARQPPPPEEEEEEANSYDSDEATTLGALEFSLLYDQDNSSLQ 406
HP P + +AA+ +A + P PE E DSD++T LG LEF+LL++ DNS+L
Sbjct: 51 HP--PNLRPAAASAVRSAPQLQPDPEPEG------DSDDSTALGTLEFTLLFEADNSALH 102
Query: 407 CTIIKAKGLKPMDSNGLADPYVKLHLLPGASKSNKLRTKTLRNTRNPIWNETLVYHGITD 466
CT +AKGLKP+ S G AD YVK +LLPGASK+++LRT T+R TR P+W ETL YHG T
Sbjct: 103 CTAHRAKGLKPLAS-GSADAYVKANLLPGASKASQLRTHTVRGTRVPVWEETLTYHGFTR 161
Query: 467 EDMQRKTLRI------SVCDEDKFGHNEF----IGETRFSLKKLKPNQRKNFNICLERVI 516
+D + KTLR +VC ++ +GE R L+KL PN+ ++F+ICLE+
Sbjct: 162 QDAECKTLRSDLGGHQAVCVRGPMVQRQWQAPSLGELRVPLRKLVPNRARSFDICLEKRR 221
Query: 517 PMKRAGTTGSARGMALYE 534
KR + +A GM+LYE
Sbjct: 222 LAKRPKSLDTACGMSLYE 239
Score = 78.2 bits (191), Expect = 2e-14
Identities = 46/130 (35%), Positives = 66/130 (50%), Gaps = 5/130 (3%)
Query: 366 RQPPPPEEEEEEANSYDSDEATTL----GALEFSLLYDQDNSSLQCTIIKAKGLKPMDSN 421
R P P+ + A S + E G + SL Y L +++ L PMD+N
Sbjct: 281 RVPSAPDPKHNSARSMEEVETEVAWEECGHVLLSLCYSSQQGGLLVGVLRCAHLAPMDAN 340
Query: 422 GLADPYVKLHLLPGASKSNKLRTKTLRNTRNPIWNETLVYHGITDEDMQRKTLRISVCDE 481
G +DP+V+L L P A K +K +T R T NP +NE Y G E++ +KTL +SV D
Sbjct: 341 GYSDPFVRLFLHPNAGKKSKFKTSVHRKTLNPEFNEEFFYSG-PREELAQKTLLVSVWDY 399
Query: 482 DKFGHNEFIG 491
D ++FIG
Sbjct: 400 DLGTADDFIG 409
>gi|193804862 synaptotagmin-like 4 [Homo sapiens]
Length = 671
Score = 173 bits (438), Expect = 5e-43
Identities = 170/668 (25%), Positives = 275/668 (41%), Gaps = 116/668 (17%)
Query: 46 LTDEEKEIINRVIARAEKMEEMEQERIGRLVDRLENMRKNVAGDGVNR-----CILCGEQ 100
L++EEK++I V+ R E++ + +++RI RL + L +++ A G C C E
Sbjct: 10 LSEEEKDLILSVLQRDEEVRKADEKRIRRLKNELLEIKRKGAKRGSQHYSDRTCARCQES 69
Query: 101 LGMLGSACVVCEDCKKNVCTKCGVETNNRLHSVWLCKICIEQREVWKRSGAWFFKGFPKQ 160
LG L C C VC C ++ +N W CK+C ++ E+ K +G WF+
Sbjct: 70 LGRLSPKTNTCRGCNHLVCRDCRIQESN---GTWRCKVCAKEIELKKATGDWFY------ 120
Query: 161 VLPQPMPIKKTKPQQPVSEPAAPEQPAPEPKHPARAPARGDSE-DRRGPGQKTGPDPASA 219
Q + + + + +PA + ++ PG+K +
Sbjct: 121 --DQKVNRFAYRTGSEIIRMSLRHKPAVSKRETVGQSLLHQTQMGDIWPGRKIIQERQKE 178
Query: 220 PGRGNYGPPVRRASEARMSSSSRDSESWDHSGGAGDSSRSPAGLRRANSVQASRPAPGSV 279
P P ++ S+ +SES D DS+ R +S+ S P
Sbjct: 179 PSVLFEVPKLKSGK----SALEAESESLDSFTADSDST------SRRDSLDKSGLFPEWK 228
Query: 280 QSPAPPQPGQPGT-PGGSRPGPGPAGRFPDQKPEVAPSDPGTTAPPREERTGGVGGYPAV 338
+ AP + T PGG F D+ + + P E +
Sbjct: 229 KMSAPKSQVEKETQPGGQNV------VFVDEGEMIFKKNTRKILRPSEYTKS------VI 276
Query: 339 GAREDRMSHPSGPYSQASAAAPQPAAARQPPPPEEEEEE---------------ANSYDS 383
R + + H SG S + P EEEEEE ++
Sbjct: 277 DLRPEDVVHESGSLGDRSKSVP----GLNVDMEEEEEEEDIDHLVKLHRQKLARSSMQSG 332
Query: 384 DEATTLGA-------------------LEFSLLYDQDNSSLQCTIIKAKGLKPMD-SNGL 423
+T+G+ + FSL Y+Q SL + + L D +
Sbjct: 333 SSMSTIGSMMSIYSEAGDFGNIFVTGRIAFSLKYEQQTQSLVVHVKECHQLAYADEAKKR 392
Query: 424 ADPYVKLHLLPGASKSNKLRTKTLRNTRNPIWNETLVYHGITDEDMQRKTLRISVCDEDK 483
++PYVK +LLP S+ K +T R+T NP+++ETL Y I + + ++TL+ SV +
Sbjct: 393 SNPYVKTYLLPDKSRQGKRKTSIKRDTINPLYDETLRYE-IPESLLAQRTLQFSVWHHGR 451
Query: 484 FGHNEFIGETRFSLKKLKPNQRKNFNICLERVIPMKRAGTTGSARGMALYEEEQVERVGD 543
FG N F+GE + K +++ L+ +P+ + S G+
Sbjct: 452 FGRNTFLGEAEIQMDSWKLDKK------LDHCLPLHGKISAESPTGLP------------ 493
Query: 544 IEERGKILVSLMY----STQQGG------------LIVGIIRCVHLAAMDANGYSDPFVK 587
+G+++VSL Y T GG L V I +L A A G SD FVK
Sbjct: 494 -SHKGELVVSLKYIPASKTPVGGDRKKSKGGEGGELQVWIKEAKNLTAAKAGGTSDSFVK 552
Query: 588 LWLKPDMGKKAKHKTQIKKKTLNPEFNEEFFYD-IKHSDLAKKSLDISVWDYDIGKSNDY 646
+L P K +K KT + KKTLNP +N F Y+ ++ DL L+++VWD + SND+
Sbjct: 553 GYLLPMRNKASKRKTPVMKKTLNPHYNHTFVYNGVRLEDLQHMCLELTVWDREPLASNDF 612
Query: 647 IGGCQLGI 654
+GG +LG+
Sbjct: 613 LGGVRLGV 620
>gi|193804860 synaptotagmin-like 4 [Homo sapiens]
Length = 671
Score = 173 bits (438), Expect = 5e-43
Identities = 170/668 (25%), Positives = 275/668 (41%), Gaps = 116/668 (17%)
Query: 46 LTDEEKEIINRVIARAEKMEEMEQERIGRLVDRLENMRKNVAGDGVNR-----CILCGEQ 100
L++EEK++I V+ R E++ + +++RI RL + L +++ A G C C E
Sbjct: 10 LSEEEKDLILSVLQRDEEVRKADEKRIRRLKNELLEIKRKGAKRGSQHYSDRTCARCQES 69
Query: 101 LGMLGSACVVCEDCKKNVCTKCGVETNNRLHSVWLCKICIEQREVWKRSGAWFFKGFPKQ 160
LG L C C VC C ++ +N W CK+C ++ E+ K +G WF+
Sbjct: 70 LGRLSPKTNTCRGCNHLVCRDCRIQESN---GTWRCKVCAKEIELKKATGDWFY------ 120
Query: 161 VLPQPMPIKKTKPQQPVSEPAAPEQPAPEPKHPARAPARGDSE-DRRGPGQKTGPDPASA 219
Q + + + + +PA + ++ PG+K +
Sbjct: 121 --DQKVNRFAYRTGSEIIRMSLRHKPAVSKRETVGQSLLHQTQMGDIWPGRKIIQERQKE 178
Query: 220 PGRGNYGPPVRRASEARMSSSSRDSESWDHSGGAGDSSRSPAGLRRANSVQASRPAPGSV 279
P P ++ S+ +SES D DS+ R +S+ S P
Sbjct: 179 PSVLFEVPKLKSGK----SALEAESESLDSFTADSDST------SRRDSLDKSGLFPEWK 228
Query: 280 QSPAPPQPGQPGT-PGGSRPGPGPAGRFPDQKPEVAPSDPGTTAPPREERTGGVGGYPAV 338
+ AP + T PGG F D+ + + P E +
Sbjct: 229 KMSAPKSQVEKETQPGGQNV------VFVDEGEMIFKKNTRKILRPSEYTKS------VI 276
Query: 339 GAREDRMSHPSGPYSQASAAAPQPAAARQPPPPEEEEEE---------------ANSYDS 383
R + + H SG S + P EEEEEE ++
Sbjct: 277 DLRPEDVVHESGSLGDRSKSVP----GLNVDMEEEEEEEDIDHLVKLHRQKLARSSMQSG 332
Query: 384 DEATTLGA-------------------LEFSLLYDQDNSSLQCTIIKAKGLKPMD-SNGL 423
+T+G+ + FSL Y+Q SL + + L D +
Sbjct: 333 SSMSTIGSMMSIYSEAGDFGNIFVTGRIAFSLKYEQQTQSLVVHVKECHQLAYADEAKKR 392
Query: 424 ADPYVKLHLLPGASKSNKLRTKTLRNTRNPIWNETLVYHGITDEDMQRKTLRISVCDEDK 483
++PYVK +LLP S+ K +T R+T NP+++ETL Y I + + ++TL+ SV +
Sbjct: 393 SNPYVKTYLLPDKSRQGKRKTSIKRDTINPLYDETLRYE-IPESLLAQRTLQFSVWHHGR 451
Query: 484 FGHNEFIGETRFSLKKLKPNQRKNFNICLERVIPMKRAGTTGSARGMALYEEEQVERVGD 543
FG N F+GE + K +++ L+ +P+ + S G+
Sbjct: 452 FGRNTFLGEAEIQMDSWKLDKK------LDHCLPLHGKISAESPTGLP------------ 493
Query: 544 IEERGKILVSLMY----STQQGG------------LIVGIIRCVHLAAMDANGYSDPFVK 587
+G+++VSL Y T GG L V I +L A A G SD FVK
Sbjct: 494 -SHKGELVVSLKYIPASKTPVGGDRKKSKGGEGGELQVWIKEAKNLTAAKAGGTSDSFVK 552
Query: 588 LWLKPDMGKKAKHKTQIKKKTLNPEFNEEFFYD-IKHSDLAKKSLDISVWDYDIGKSNDY 646
+L P K +K KT + KKTLNP +N F Y+ ++ DL L+++VWD + SND+
Sbjct: 553 GYLLPMRNKASKRKTPVMKKTLNPHYNHTFVYNGVRLEDLQHMCLELTVWDREPLASNDF 612
Query: 647 IGGCQLGI 654
+GG +LG+
Sbjct: 613 LGGVRLGV 620
>gi|38570146 synaptotagmin VII [Homo sapiens]
Length = 403
Score = 172 bits (436), Expect = 9e-43
Identities = 109/312 (34%), Positives = 160/312 (51%), Gaps = 29/312 (9%)
Query: 371 PEEEEEEANSYDSDEATTLGALEFSLLYDQDNSSLQCTIIKAKGLKPMDSNGLADPYVKL 430
P EE+EA+ S E LG ++FS+ Y+ S+L I+KA+ L D +G +DP+VK+
Sbjct: 120 PGSEEDEAHEGCSRE--NLGRIQFSVGYNFQESTLTVKIMKAQELPAKDFSGTSDPFVKI 177
Query: 431 HLLPGASKSNKLRTKTLRNTRNPIWNETLVYHGITDEDMQRKTLRISVCDEDKFGHNEFI 490
+LLP K +KL TK R NP WNET ++ G E + ++ L + V D D+F N+ I
Sbjct: 178 YLLP--DKKHKLETKVKRKNLNPHWNETFLFEGFPYEKVVQRILYLQVLDYDRFSRNDPI 235
Query: 491 GETRFSLKKLKPNQRKNFNICLERVIPMKRAGTTGSARGMALYEEEQVERVGDIEERGKI 550
GE L K+ Q + F L+ + GS RG++
Sbjct: 236 GEVSIPLNKVDLTQMQTFWKDLKPC-------SDGSG------------------SRGEL 270
Query: 551 LVSLMYSTQQGGLIVGIIRCVHLAAMDANGYSDPFVKLWLKPDMGKKAKHKTQIKKKTLN 610
L+SL Y+ +IV II+ +L AMD G SDP+VK+WL + K KT K+ LN
Sbjct: 271 LLSLCYNPSANSIIVNIIKARNLKAMDIGGTSDPYVKVWLMYKDKRVEKKKTVTMKRNLN 330
Query: 611 PEFNEEFFYDIKHSDLAKKSLDISVWDYDIGKSNDYIGGCQLGISAKGERLKHWYECLKN 670
P FNE F +DI L + ++ I+V D D ND IG L + +KHW + +
Sbjct: 331 PIFNESFAFDIPTEKLRETTIIITVMDKDKLSRNDVIGKIYLSWKSGPGEVKHWKDMIAR 390
Query: 671 KDKKIERWHQLQ 682
+ + +WHQL+
Sbjct: 391 PRQPVAQWHQLK 402
>gi|211059429 synaptotagmin II [Homo sapiens]
Length = 419
Score = 169 bits (427), Expect = 1e-41
Identities = 107/315 (33%), Positives = 160/315 (50%), Gaps = 27/315 (8%)
Query: 375 EEEANSYDSDEATTLGALEFSLLYDQDNSSLQCTIIKAKGLKPMDSNGLADPYVKLHLLP 434
E E + E LG L+FSL YD + L +++A L +D G +DPYVK+ LLP
Sbjct: 126 EGEGEGEEEKEPENLGKLQFSLDYDFQANQLTVGVLQAAELPALDMGGTSDPYVKVFLLP 185
Query: 435 GASKSNKLRTKTLRNTRNPIWNETLVYHGITDEDMQRKTLRISVCDEDKFGHNEFIGETR 494
K K TK R T NP +NET + + +++ KTL +++ D D+F ++ IGE +
Sbjct: 186 --DKKKKYETKVHRKTLNPAFNETFTFK-VPYQELGGKTLVMAIYDFDRFSKHDIIGEVK 242
Query: 495 FSLKKLKPNQRKNFNICLERVIPMKRAGTTGSARGMALYEEEQVERVGDIEERGKILVSL 554
+ + Q P++ R + E+E+ E++GDI SL
Sbjct: 243 VPMNTVDLGQ------------PIEEW------RDLQGGEKEEPEKLGDI------CTSL 278
Query: 555 MYSTQQGGLIVGIIRCVHLAAMDANGYSDPFVKLWLKPDMGKKAKHKTQIKKKTLNPEFN 614
Y G L V I+ +L MD G SDP+VK+ L + + K KT +KKKTLNP FN
Sbjct: 279 RYVPTAGKLTVCILEAKNLKKMDVGGLSDPYVKIHLMQNGKRLKKKKTTVKKKTLNPYFN 338
Query: 615 EEFFYDIKHSDLAKKSLDISVWDYDIGKSNDYIGGCQLGISAKGERLKHWYECLKNKDKK 674
E F ++I + K + ++V DYD N+ IG +G +A G L+HW + L N +
Sbjct: 339 ESFSFEIPFEQIQKVQVVVTVLDYDKLGKNEAIGKIFVGSNATGTELRHWSDMLANPRRP 398
Query: 675 IERWHQLQNENHVSS 689
I +WH L+ E V +
Sbjct: 399 IAQWHSLKPEEEVDA 413
Score = 79.7 bits (195), Expect = 8e-15
Identities = 45/122 (36%), Positives = 66/122 (54%), Gaps = 1/122 (0%)
Query: 371 PEEEEEEANSYDSDEATTLGALEFSLLYDQDNSSLQCTIIKAKGLKPMDSNGLADPYVKL 430
P EE + + +E LG + SL Y L I++AK LK MD GL+DPYVK+
Sbjct: 253 PIEEWRDLQGGEKEEPEKLGDICTSLRYVPTAGKLTVCILEAKNLKKMDVGGLSDPYVKI 312
Query: 431 HLLPGASKSNKLRTKTLRNTRNPIWNETLVYHGITDEDMQRKTLRISVCDEDKFGHNEFI 490
HL+ + K +T + T NP +NE+ + I E +Q+ + ++V D DK G NE I
Sbjct: 313 HLMQNGKRLKKKKTTVKKKTLNPYFNESFSFE-IPFEQIQKVQVVVTVLDYDKLGKNEAI 371
Query: 491 GE 492
G+
Sbjct: 372 GK 373
>gi|31543670 synaptotagmin II [Homo sapiens]
Length = 419
Score = 169 bits (427), Expect = 1e-41
Identities = 107/315 (33%), Positives = 160/315 (50%), Gaps = 27/315 (8%)
Query: 375 EEEANSYDSDEATTLGALEFSLLYDQDNSSLQCTIIKAKGLKPMDSNGLADPYVKLHLLP 434
E E + E LG L+FSL YD + L +++A L +D G +DPYVK+ LLP
Sbjct: 126 EGEGEGEEEKEPENLGKLQFSLDYDFQANQLTVGVLQAAELPALDMGGTSDPYVKVFLLP 185
Query: 435 GASKSNKLRTKTLRNTRNPIWNETLVYHGITDEDMQRKTLRISVCDEDKFGHNEFIGETR 494
K K TK R T NP +NET + + +++ KTL +++ D D+F ++ IGE +
Sbjct: 186 --DKKKKYETKVHRKTLNPAFNETFTFK-VPYQELGGKTLVMAIYDFDRFSKHDIIGEVK 242
Query: 495 FSLKKLKPNQRKNFNICLERVIPMKRAGTTGSARGMALYEEEQVERVGDIEERGKILVSL 554
+ + Q P++ R + E+E+ E++GDI SL
Sbjct: 243 VPMNTVDLGQ------------PIEEW------RDLQGGEKEEPEKLGDI------CTSL 278
Query: 555 MYSTQQGGLIVGIIRCVHLAAMDANGYSDPFVKLWLKPDMGKKAKHKTQIKKKTLNPEFN 614
Y G L V I+ +L MD G SDP+VK+ L + + K KT +KKKTLNP FN
Sbjct: 279 RYVPTAGKLTVCILEAKNLKKMDVGGLSDPYVKIHLMQNGKRLKKKKTTVKKKTLNPYFN 338
Query: 615 EEFFYDIKHSDLAKKSLDISVWDYDIGKSNDYIGGCQLGISAKGERLKHWYECLKNKDKK 674
E F ++I + K + ++V DYD N+ IG +G +A G L+HW + L N +
Sbjct: 339 ESFSFEIPFEQIQKVQVVVTVLDYDKLGKNEAIGKIFVGSNATGTELRHWSDMLANPRRP 398
Query: 675 IERWHQLQNENHVSS 689
I +WH L+ E V +
Sbjct: 399 IAQWHSLKPEEEVDA 413
Score = 79.7 bits (195), Expect = 8e-15
Identities = 45/122 (36%), Positives = 66/122 (54%), Gaps = 1/122 (0%)
Query: 371 PEEEEEEANSYDSDEATTLGALEFSLLYDQDNSSLQCTIIKAKGLKPMDSNGLADPYVKL 430
P EE + + +E LG + SL Y L I++AK LK MD GL+DPYVK+
Sbjct: 253 PIEEWRDLQGGEKEEPEKLGDICTSLRYVPTAGKLTVCILEAKNLKKMDVGGLSDPYVKI 312
Query: 431 HLLPGASKSNKLRTKTLRNTRNPIWNETLVYHGITDEDMQRKTLRISVCDEDKFGHNEFI 490
HL+ + K +T + T NP +NE+ + I E +Q+ + ++V D DK G NE I
Sbjct: 313 HLMQNGKRLKKKKTTVKKKTLNPYFNESFSFE-IPFEQIQKVQVVVTVLDYDKLGKNEAI 371
Query: 491 GE 492
G+
Sbjct: 372 GK 373
>gi|209447073 synaptotagmin I [Homo sapiens]
Length = 422
Score = 167 bits (424), Expect = 2e-41
Identities = 111/320 (34%), Positives = 159/320 (49%), Gaps = 38/320 (11%)
Query: 373 EEEEEANSYDSDEATTLGALEFSLLYDQDNSSLQCTIIKAKGLKPMDSNGLADPYVKLHL 432
EE+EE E LG L++SL YD N+ L II+A L +D G +DPYVK+ L
Sbjct: 132 EEKEEPK-----EEEKLGKLQYSLDYDFQNNQLLVGIIQAAELPALDMGGTSDPYVKVFL 186
Query: 433 LPGASKSNKLRTKTLRNTRNPIWNETLVYHGITDEDMQRKTLRISVCDEDKFGHNEFIGE 492
LP K K TK R T NP++NE + + ++ KTL ++V D D+F ++ IGE
Sbjct: 187 LP--DKKKKFETKVHRKTLNPVFNEQFTFK-VPYSELGGKTLVMAVYDFDRFSKHDIIGE 243
Query: 493 TRFSLKKLKPNQRKNFNICLERVIPMKRAG---TTGSARGMALYEEEQVERVGDIEERGK 549
+ +PM T R + E+E+ E++GDI
Sbjct: 244 FK---------------------VPMNTVDFGHVTEEWRDLQSAEKEEQEKLGDI----- 277
Query: 550 ILVSLMYSTQQGGLIVGIIRCVHLAAMDANGYSDPFVKLWLKPDMGKKAKHKTQIKKKTL 609
SL Y G L V I+ +L MD G SDP+VK+ L + + K KT IKK TL
Sbjct: 278 -CFSLRYVPTAGKLTVVILEAKNLKKMDVGGLSDPYVKIHLMQNGKRLKKKKTTIKKNTL 336
Query: 610 NPEFNEEFFYDIKHSDLAKKSLDISVWDYDIGKSNDYIGGCQLGISAKGERLKHWYECLK 669
NP +NE F +++ + K + ++V DYD ND IG +G ++ G L+HW + L
Sbjct: 337 NPYYNESFSFEVPFEQIQKVQVVVTVLDYDKIGKNDAIGKVFVGYNSTGAELRHWSDMLA 396
Query: 670 NKDKKIERWHQLQNENHVSS 689
N + I +WH LQ E V +
Sbjct: 397 NPRRPIAQWHTLQVEEEVDA 416
Score = 95.5 bits (236), Expect = 1e-19
Identities = 50/117 (42%), Positives = 76/117 (64%), Gaps = 2/117 (1%)
Query: 532 LYEEEQVERVGDIEERGKILVSLMYSTQQGGLIVGIIRCVHLAAMDANGYSDPFVKLWLK 591
L + E+ E + E+ GK+ SL Y Q L+VGII+ L A+D G SDP+VK++L
Sbjct: 128 LTDGEEKEEPKEEEKLGKLQYSLDYDFQNNQLLVGIIQAAELPALDMGGTSDPYVKVFLL 187
Query: 592 PDMGKKAKHKTQIKKKTLNPEFNEEFFYDIKHSDLAKKSLDISVWDYDIGKSNDYIG 648
PD KK K +T++ +KTLNP FNE+F + + +S+L K+L ++V+D+D +D IG
Sbjct: 188 PD--KKKKFETKVHRKTLNPVFNEQFTFKVPYSELGGKTLVMAVYDFDRFSKHDIIG 242
>gi|5032139 synaptotagmin I [Homo sapiens]
Length = 422
Score = 167 bits (424), Expect = 2e-41
Identities = 111/320 (34%), Positives = 159/320 (49%), Gaps = 38/320 (11%)
Query: 373 EEEEEANSYDSDEATTLGALEFSLLYDQDNSSLQCTIIKAKGLKPMDSNGLADPYVKLHL 432
EE+EE E LG L++SL YD N+ L II+A L +D G +DPYVK+ L
Sbjct: 132 EEKEEPK-----EEEKLGKLQYSLDYDFQNNQLLVGIIQAAELPALDMGGTSDPYVKVFL 186
Query: 433 LPGASKSNKLRTKTLRNTRNPIWNETLVYHGITDEDMQRKTLRISVCDEDKFGHNEFIGE 492
LP K K TK R T NP++NE + + ++ KTL ++V D D+F ++ IGE
Sbjct: 187 LP--DKKKKFETKVHRKTLNPVFNEQFTFK-VPYSELGGKTLVMAVYDFDRFSKHDIIGE 243
Query: 493 TRFSLKKLKPNQRKNFNICLERVIPMKRAG---TTGSARGMALYEEEQVERVGDIEERGK 549
+ +PM T R + E+E+ E++GDI
Sbjct: 244 FK---------------------VPMNTVDFGHVTEEWRDLQSAEKEEQEKLGDI----- 277
Query: 550 ILVSLMYSTQQGGLIVGIIRCVHLAAMDANGYSDPFVKLWLKPDMGKKAKHKTQIKKKTL 609
SL Y G L V I+ +L MD G SDP+VK+ L + + K KT IKK TL
Sbjct: 278 -CFSLRYVPTAGKLTVVILEAKNLKKMDVGGLSDPYVKIHLMQNGKRLKKKKTTIKKNTL 336
Query: 610 NPEFNEEFFYDIKHSDLAKKSLDISVWDYDIGKSNDYIGGCQLGISAKGERLKHWYECLK 669
NP +NE F +++ + K + ++V DYD ND IG +G ++ G L+HW + L
Sbjct: 337 NPYYNESFSFEVPFEQIQKVQVVVTVLDYDKIGKNDAIGKVFVGYNSTGAELRHWSDMLA 396
Query: 670 NKDKKIERWHQLQNENHVSS 689
N + I +WH LQ E V +
Sbjct: 397 NPRRPIAQWHTLQVEEEVDA 416
Score = 95.5 bits (236), Expect = 1e-19
Identities = 50/117 (42%), Positives = 76/117 (64%), Gaps = 2/117 (1%)
Query: 532 LYEEEQVERVGDIEERGKILVSLMYSTQQGGLIVGIIRCVHLAAMDANGYSDPFVKLWLK 591
L + E+ E + E+ GK+ SL Y Q L+VGII+ L A+D G SDP+VK++L
Sbjct: 128 LTDGEEKEEPKEEEKLGKLQYSLDYDFQNNQLLVGIIQAAELPALDMGGTSDPYVKVFLL 187
Query: 592 PDMGKKAKHKTQIKKKTLNPEFNEEFFYDIKHSDLAKKSLDISVWDYDIGKSNDYIG 648
PD KK K +T++ +KTLNP FNE+F + + +S+L K+L ++V+D+D +D IG
Sbjct: 188 PD--KKKKFETKVHRKTLNPVFNEQFTFKVPYSELGGKTLVMAVYDFDRFSKHDIIG 242
>gi|209447070 synaptotagmin I [Homo sapiens]
Length = 422
Score = 167 bits (424), Expect = 2e-41
Identities = 111/320 (34%), Positives = 159/320 (49%), Gaps = 38/320 (11%)
Query: 373 EEEEEANSYDSDEATTLGALEFSLLYDQDNSSLQCTIIKAKGLKPMDSNGLADPYVKLHL 432
EE+EE E LG L++SL YD N+ L II+A L +D G +DPYVK+ L
Sbjct: 132 EEKEEPK-----EEEKLGKLQYSLDYDFQNNQLLVGIIQAAELPALDMGGTSDPYVKVFL 186
Query: 433 LPGASKSNKLRTKTLRNTRNPIWNETLVYHGITDEDMQRKTLRISVCDEDKFGHNEFIGE 492
LP K K TK R T NP++NE + + ++ KTL ++V D D+F ++ IGE
Sbjct: 187 LP--DKKKKFETKVHRKTLNPVFNEQFTFK-VPYSELGGKTLVMAVYDFDRFSKHDIIGE 243
Query: 493 TRFSLKKLKPNQRKNFNICLERVIPMKRAG---TTGSARGMALYEEEQVERVGDIEERGK 549
+ +PM T R + E+E+ E++GDI
Sbjct: 244 FK---------------------VPMNTVDFGHVTEEWRDLQSAEKEEQEKLGDI----- 277
Query: 550 ILVSLMYSTQQGGLIVGIIRCVHLAAMDANGYSDPFVKLWLKPDMGKKAKHKTQIKKKTL 609
SL Y G L V I+ +L MD G SDP+VK+ L + + K KT IKK TL
Sbjct: 278 -CFSLRYVPTAGKLTVVILEAKNLKKMDVGGLSDPYVKIHLMQNGKRLKKKKTTIKKNTL 336
Query: 610 NPEFNEEFFYDIKHSDLAKKSLDISVWDYDIGKSNDYIGGCQLGISAKGERLKHWYECLK 669
NP +NE F +++ + K + ++V DYD ND IG +G ++ G L+HW + L
Sbjct: 337 NPYYNESFSFEVPFEQIQKVQVVVTVLDYDKIGKNDAIGKVFVGYNSTGAELRHWSDMLA 396
Query: 670 NKDKKIERWHQLQNENHVSS 689
N + I +WH LQ E V +
Sbjct: 397 NPRRPIAQWHTLQVEEEVDA 416
Score = 95.5 bits (236), Expect = 1e-19
Identities = 50/117 (42%), Positives = 76/117 (64%), Gaps = 2/117 (1%)
Query: 532 LYEEEQVERVGDIEERGKILVSLMYSTQQGGLIVGIIRCVHLAAMDANGYSDPFVKLWLK 591
L + E+ E + E+ GK+ SL Y Q L+VGII+ L A+D G SDP+VK++L
Sbjct: 128 LTDGEEKEEPKEEEKLGKLQYSLDYDFQNNQLLVGIIQAAELPALDMGGTSDPYVKVFLL 187
Query: 592 PDMGKKAKHKTQIKKKTLNPEFNEEFFYDIKHSDLAKKSLDISVWDYDIGKSNDYIG 648
PD KK K +T++ +KTLNP FNE+F + + +S+L K+L ++V+D+D +D IG
Sbjct: 188 PD--KKKKFETKVHRKTLNPVFNEQFTFKVPYSELGGKTLVMAVYDFDRFSKHDIIG 242
>gi|45504376 synaptotagmin VI [Homo sapiens]
Length = 425
Score = 167 bits (422), Expect = 4e-41
Identities = 112/326 (34%), Positives = 172/326 (52%), Gaps = 28/326 (8%)
Query: 358 AAPQPAAARQPPPPEEEEEEANSYDS-DEAT-TLGALEFSLLYDQDNSSLQCTIIKAKGL 415
AA QP + + P +++ + D+ EAT + G + FSL YD + +L I+KA L
Sbjct: 112 AAEQPTSIGRIKPELYKQKSVDGEDAKSEATKSCGKINFSLRYDYETETLIVRILKAFDL 171
Query: 416 KPMDSNGLADPYVKLHLLPGASKSNKLRTKTLRNTRNPIWNETLVYHGITDEDMQRKTLR 475
D G +DPYVK++LLP + KL+T+ R T NP ++E + + E++ + L
Sbjct: 172 PAKDFCGSSDPYVKIYLLP--DRKCKLQTRVHRKTLNPTFDENF-HFPVPYEELADRKLH 228
Query: 476 ISVCDEDKFGHNEFIGETRFSLKKLKPNQRKNFNICLERVIPMKRAGTTGSARGMALYEE 535
+SV D D+F ++ IGE + L+ + + +R +++++
Sbjct: 229 LSVFDFDRFSRHDMIGE-----------------VILDNLFE-----ASDLSRETSIWKD 266
Query: 536 EQVERVGDIEERGKILVSLMYSTQQGGLIVGIIRCVHLAAMDANGYSDPFVKLWLKPDMG 595
Q ++ G+I+ SL Y G L + +I+C +L AMD GYSDP+VK+ L D
Sbjct: 267 IQYATSESVD-LGEIMFSLCYLPTAGRLTLTVIKCRNLKAMDITGYSDPYVKVSLLCDGR 325
Query: 596 KKAKHKTQIKKKTLNPEFNEEFFYDIKHSDLAKKSLDISVWDYDIGKSNDYIGGCQLGIS 655
+ K KT IKK TLNP +NE +DI ++ + SL ISV DYD N+ IG C++GI+
Sbjct: 326 RLKKKKTTIKKNTLNPVYNEAIIFDIPPENMDQVSLLISVMDYDRVGHNEIIGVCRVGIT 385
Query: 656 AKGERLKHWYECLKNKDKKIERWHQL 681
A+G HW E L K I WH L
Sbjct: 386 AEGLGRDHWNEMLAYPRKPIAHWHSL 411
>gi|238550198 synaptotagmin III [Homo sapiens]
Length = 590
Score = 165 bits (418), Expect = 1e-40
Identities = 152/510 (29%), Positives = 212/510 (41%), Gaps = 74/510 (14%)
Query: 190 PKHPARAPARGDSEDRRGPGQKTGPD-PASAPGRGNYGPPVRRASEARMSSSSRDSESWD 248
P H A A + PG G D P + + P A+ A S+ S
Sbjct: 130 PHHHAHAAHHPPFAELLEPGSLGGSDTPEPSYLDMDSYPEAAAAAVAAGVKPSQTSPELP 189
Query: 249 HSGGAGDS----SRSPAGLRRANSVQASRPAPGSVQSPAPPQPGQPGTPGGSRPGPGPAG 304
GGAG S GL A S Q + + PA P+P T S+P P
Sbjct: 190 SEGGAGSGLLLLPPSGGGLPSAQSHQQVTSLAPTTRYPALPRPLTQQTLT-SQPDPSS-- 246
Query: 305 RFPDQKPEVAPSDPGTTAPPREERTGGVGGYPAVGAREDRMSHPSGPYSQASAAAPQPAA 364
+++P P P EE+ +G + + +GP + S P
Sbjct: 247 ---EERPPALP----LPLPGGEEKA------KLIGQIKPELYQGTGPGGRRSGGGPGSGE 293
Query: 365 ARQPPPPEEEEEEANSYDSDEATTLGALEFSLLYDQDNSSLQCTIIKAKGLKPMDSNGLA 424
A P G + F+L Y + L I++A L DSNG +
Sbjct: 294 AGTGAP------------------CGRISFALRYLYGSDQLVVRILQALDLPAKDSNGFS 335
Query: 425 DPYVKLHLLPGASKSNKLRTKTLRNTRNPIWNETLVYHGITDEDMQRKTLRISVCDEDKF 484
DPYVK++LLP K K +TK R T NP++NET + E QRK L SV D D+F
Sbjct: 336 DPYVKIYLLPDRKK--KFQTKVHRKTLNPVFNETFQFSVPLAELAQRK-LHFSVYDFDRF 392
Query: 485 GHNEFIGET----RFSLKKLKPNQRKNFNICLERVIPMKRAGTTGSARGMALYEEEQVER 540
++ IG+ L + P++ P+ R + VE
Sbjct: 393 SRHDLIGQVVLDNLLELAEQPPDR------------PLWR---------------DIVEG 425
Query: 541 VGDIEERGKILVSLMYSTQQGGLIVGIIRCVHLAAMDANGYSDPFVKLWLKPDMGKKAKH 600
+ + G++ SL Y G L V II+ +L AMD G+SDP+VK L + + K
Sbjct: 426 GSEKADLGELNFSLCYLPTAGRLTVTIIKASNLKAMDLTGFSDPYVKASLISEGRRLKKR 485
Query: 601 KTQIKKKTLNPEFNEEFFYDIKHSDLAKKSLDISVWDYDIGKSNDYIGGCQLGISAKGER 660
KT IKK TLNP +NE +D+ + L I+V DYD N+ IG C++G A
Sbjct: 486 KTSIKKNTLNPTYNEALVFDVAPESVENVGLSIAVVDYDCIGHNEVIGVCRVGPDAADPH 545
Query: 661 -LKHWYECLKNKDKKIERWHQLQNENHVSS 689
+HW E L N K +E WHQL E V+S
Sbjct: 546 GREHWAEMLANPRKPVEHWHQLVEEKTVTS 575
>gi|238550196 synaptotagmin III [Homo sapiens]
Length = 590
Score = 165 bits (418), Expect = 1e-40
Identities = 152/510 (29%), Positives = 212/510 (41%), Gaps = 74/510 (14%)
Query: 190 PKHPARAPARGDSEDRRGPGQKTGPD-PASAPGRGNYGPPVRRASEARMSSSSRDSESWD 248
P H A A + PG G D P + + P A+ A S+ S
Sbjct: 130 PHHHAHAAHHPPFAELLEPGSLGGSDTPEPSYLDMDSYPEAAAAAVAAGVKPSQTSPELP 189
Query: 249 HSGGAGDS----SRSPAGLRRANSVQASRPAPGSVQSPAPPQPGQPGTPGGSRPGPGPAG 304
GGAG S GL A S Q + + PA P+P T S+P P
Sbjct: 190 SEGGAGSGLLLLPPSGGGLPSAQSHQQVTSLAPTTRYPALPRPLTQQTLT-SQPDPSS-- 246
Query: 305 RFPDQKPEVAPSDPGTTAPPREERTGGVGGYPAVGAREDRMSHPSGPYSQASAAAPQPAA 364
+++P P P EE+ +G + + +GP + S P
Sbjct: 247 ---EERPPALP----LPLPGGEEKA------KLIGQIKPELYQGTGPGGRRSGGGPGSGE 293
Query: 365 ARQPPPPEEEEEEANSYDSDEATTLGALEFSLLYDQDNSSLQCTIIKAKGLKPMDSNGLA 424
A P G + F+L Y + L I++A L DSNG +
Sbjct: 294 AGTGAP------------------CGRISFALRYLYGSDQLVVRILQALDLPAKDSNGFS 335
Query: 425 DPYVKLHLLPGASKSNKLRTKTLRNTRNPIWNETLVYHGITDEDMQRKTLRISVCDEDKF 484
DPYVK++LLP K K +TK R T NP++NET + E QRK L SV D D+F
Sbjct: 336 DPYVKIYLLPDRKK--KFQTKVHRKTLNPVFNETFQFSVPLAELAQRK-LHFSVYDFDRF 392
Query: 485 GHNEFIGET----RFSLKKLKPNQRKNFNICLERVIPMKRAGTTGSARGMALYEEEQVER 540
++ IG+ L + P++ P+ R + VE
Sbjct: 393 SRHDLIGQVVLDNLLELAEQPPDR------------PLWR---------------DIVEG 425
Query: 541 VGDIEERGKILVSLMYSTQQGGLIVGIIRCVHLAAMDANGYSDPFVKLWLKPDMGKKAKH 600
+ + G++ SL Y G L V II+ +L AMD G+SDP+VK L + + K
Sbjct: 426 GSEKADLGELNFSLCYLPTAGRLTVTIIKASNLKAMDLTGFSDPYVKASLISEGRRLKKR 485
Query: 601 KTQIKKKTLNPEFNEEFFYDIKHSDLAKKSLDISVWDYDIGKSNDYIGGCQLGISAKGER 660
KT IKK TLNP +NE +D+ + L I+V DYD N+ IG C++G A
Sbjct: 486 KTSIKKNTLNPTYNEALVFDVAPESVENVGLSIAVVDYDCIGHNEVIGVCRVGPDAADPH 545
Query: 661 -LKHWYECLKNKDKKIERWHQLQNENHVSS 689
+HW E L N K +E WHQL E V+S
Sbjct: 546 GREHWAEMLANPRKPVEHWHQLVEEKTVTS 575
>gi|14150054 synaptotagmin III [Homo sapiens]
Length = 590
Score = 165 bits (418), Expect = 1e-40
Identities = 152/510 (29%), Positives = 212/510 (41%), Gaps = 74/510 (14%)
Query: 190 PKHPARAPARGDSEDRRGPGQKTGPD-PASAPGRGNYGPPVRRASEARMSSSSRDSESWD 248
P H A A + PG G D P + + P A+ A S+ S
Sbjct: 130 PHHHAHAAHHPPFAELLEPGSLGGSDTPEPSYLDMDSYPEAAAAAVAAGVKPSQTSPELP 189
Query: 249 HSGGAGDS----SRSPAGLRRANSVQASRPAPGSVQSPAPPQPGQPGTPGGSRPGPGPAG 304
GGAG S GL A S Q + + PA P+P T S+P P
Sbjct: 190 SEGGAGSGLLLLPPSGGGLPSAQSHQQVTSLAPTTRYPALPRPLTQQTLT-SQPDPSS-- 246
Query: 305 RFPDQKPEVAPSDPGTTAPPREERTGGVGGYPAVGAREDRMSHPSGPYSQASAAAPQPAA 364
+++P P P EE+ +G + + +GP + S P
Sbjct: 247 ---EERPPALP----LPLPGGEEKA------KLIGQIKPELYQGTGPGGRRSGGGPGSGE 293
Query: 365 ARQPPPPEEEEEEANSYDSDEATTLGALEFSLLYDQDNSSLQCTIIKAKGLKPMDSNGLA 424
A P G + F+L Y + L I++A L DSNG +
Sbjct: 294 AGTGAP------------------CGRISFALRYLYGSDQLVVRILQALDLPAKDSNGFS 335
Query: 425 DPYVKLHLLPGASKSNKLRTKTLRNTRNPIWNETLVYHGITDEDMQRKTLRISVCDEDKF 484
DPYVK++LLP K K +TK R T NP++NET + E QRK L SV D D+F
Sbjct: 336 DPYVKIYLLPDRKK--KFQTKVHRKTLNPVFNETFQFSVPLAELAQRK-LHFSVYDFDRF 392
Query: 485 GHNEFIGET----RFSLKKLKPNQRKNFNICLERVIPMKRAGTTGSARGMALYEEEQVER 540
++ IG+ L + P++ P+ R + VE
Sbjct: 393 SRHDLIGQVVLDNLLELAEQPPDR------------PLWR---------------DIVEG 425
Query: 541 VGDIEERGKILVSLMYSTQQGGLIVGIIRCVHLAAMDANGYSDPFVKLWLKPDMGKKAKH 600
+ + G++ SL Y G L V II+ +L AMD G+SDP+VK L + + K
Sbjct: 426 GSEKADLGELNFSLCYLPTAGRLTVTIIKASNLKAMDLTGFSDPYVKASLISEGRRLKKR 485
Query: 601 KTQIKKKTLNPEFNEEFFYDIKHSDLAKKSLDISVWDYDIGKSNDYIGGCQLGISAKGER 660
KT IKK TLNP +NE +D+ + L I+V DYD N+ IG C++G A
Sbjct: 486 KTSIKKNTLNPTYNEALVFDVAPESVENVGLSIAVVDYDCIGHNEVIGVCRVGPDAADPH 545
Query: 661 -LKHWYECLKNKDKKIERWHQLQNENHVSS 689
+HW E L N K +E WHQL E V+S
Sbjct: 546 GREHWAEMLANPRKPVEHWHQLVEEKTVTS 575
>gi|39752671 synaptotagmin X [Homo sapiens]
Length = 523
Score = 159 bits (403), Expect = 6e-39
Identities = 106/315 (33%), Positives = 153/315 (48%), Gaps = 26/315 (8%)
Query: 367 QPPPPEEEEEEANSYDSDEATTLGALEFSLLYDQDNSSLQCTIIKAKGLKPMDSNGLADP 426
+P +++ ++ +++ G L F+L YD +N L IIKA L D G +DP
Sbjct: 210 KPELYKQKSVDSEGNQNEDVKICGKLNFTLQYDYENELLVVKIIKALDLPAKDFTGTSDP 269
Query: 427 YVKLHLLPGASKSNKLRTKTLRNTRNPIWNETLVYHGITDEDMQRKTLRISVCDEDKFGH 486
YVK++LLP K K +T+ R T NP+++ET + D+ RK L SV D D+F
Sbjct: 270 YVKMYLLPDRKK--KFQTRVHRKTLNPLFDETFQFPVAYDQLSNRK-LHFSVYDFDRFSR 326
Query: 487 NEFIGETRFSLKKLKPNQRKNFNICLERVIPMKRAGTTGSARGMALYEEEQVERVGDIEE 546
++ IGE L V + R T A E +
Sbjct: 327 HDMIGEVILDN--------------LFEVSDLSREATVWKDIHCATTESIDL-------- 364
Query: 547 RGKILVSLMYSTQQGGLIVGIIRCVHLAAMDANGYSDPFVKLWLKPDMGKKAKHKTQIKK 606
G+I+ SL Y G + + +I+C +L AMD G SDP+VK+ L + + K KT KK
Sbjct: 365 -GEIMFSLCYLPTAGRMTLTVIKCRNLKAMDITGSSDPYVKVSLMCEGRRLKKRKTTTKK 423
Query: 607 KTLNPEFNEEFFYDIKHSDLAKKSLDISVWDYDIGKSNDYIGGCQLGISAKGERLKHWYE 666
TLNP +NE +DI ++ + SL I+V DYD N+ IG C+ G+ A+G HW E
Sbjct: 424 NTLNPVYNEAIIFDIPPENVDQVSLSIAVMDYDRVGHNEVIGVCRTGLDAEGLGRDHWNE 483
Query: 667 CLKNKDKKIERWHQL 681
L K I WH L
Sbjct: 484 MLAYHRKPITHWHPL 498
Score = 84.7 bits (208), Expect = 3e-16
Identities = 49/139 (35%), Positives = 82/139 (58%), Gaps = 9/139 (6%)
Query: 517 PMKRAGTTGSARGMA---LYEEEQVERVG----DIEERGKILVSLMYSTQQGGLIVGIIR 569
P+ + G T ++ G LY+++ V+ G D++ GK+ +L Y + L+V II+
Sbjct: 195 PVLQRGETTTSIGRIKPELYKQKSVDSEGNQNEDVKICGKLNFTLQYDYENELLVVKIIK 254
Query: 570 CVHLAAMDANGYSDPFVKLWLKPDMGKKAKHKTQIKKKTLNPEFNEEFFYDIKHSDLAKK 629
+ L A D G SDP+VK++L PD +K K +T++ +KTLNP F+E F + + + L+ +
Sbjct: 255 ALDLPAKDFTGTSDPYVKMYLLPD--RKKKFQTRVHRKTLNPLFDETFQFPVAYDQLSNR 312
Query: 630 SLDISVWDYDIGKSNDYIG 648
L SV+D+D +D IG
Sbjct: 313 KLHFSVYDFDRFSRHDMIG 331
>gi|92859638 synaptotagmin V [Homo sapiens]
Length = 386
Score = 155 bits (391), Expect = 2e-37
Identities = 105/321 (32%), Positives = 156/321 (48%), Gaps = 30/321 (9%)
Query: 370 PPEEEEEEANSYDSDEATT---LGALEFSLLYDQDNSSLQCTIIKAKGLKPMDSNGLADP 426
P EE E A S + LG L++SL YD + L I++A GL +D G +DP
Sbjct: 87 PEVEELEPAPSGPGQQVADKHELGRLQYSLDYDFQSGQLLVGILQAMGLAALDLGGSSDP 146
Query: 427 YVKLHLLPGASKSNKLRTKTLRNTRNPIWNETLVYHGITDEDMQRKTLRISVCDEDKFGH 486
YV+++LLP K + TK R T NP + ET + + ++ + L ++V D D+F
Sbjct: 147 YVRVYLLP--DKRRRYETKVHRQTLNPHFGETFAFK-VPYVELGGRVLVMAVYDFDRFSR 203
Query: 487 NEFIGETRFSLKKLKPNQRKNFNICLERVIPMKRAGTTGSARGMALYEEEQVERVGDIEE 546
N+ IGE R +PM + R + + E Q + E+
Sbjct: 204 NDAIGEVR---------------------VPMS---SVDLGRPVQAWRELQAAPREEQEK 239
Query: 547 RGKILVSLMYSTQQGGLIVGIIRCVHLAAMDANGYSDPFVKLWLKPDMGKKAKHKTQIKK 606
G I SL Y G L V ++ +L MD G SDP+VK+ L K K KT IKK
Sbjct: 240 LGDICFSLRYVPTAGKLTVIVLEAKNLKKMDVGGLSDPYVKVHLLQGGKKVRKKKTTIKK 299
Query: 607 KTLNPEFNEEFFYDIKHSDLAKKSLDISVWDYDIGKSNDYIGGCQLGISAKGERLKHWYE 666
TLNP +NE F +++ + K ++++V DYD N+ IG +G +A G L+HW +
Sbjct: 300 NTLNPYYNEAFSFEVPCDQVQKVQVELTVLDYDKLGKNEAIGRVAVGAAAGGAGLRHWAD 359
Query: 667 CLKNKDKKIERWHQLQNENHV 687
L N + I +WH L+ + V
Sbjct: 360 MLANPRRPIAQWHSLRPPDRV 380
>gi|24308219 synaptotagmin IV [Homo sapiens]
Length = 425
Score = 148 bits (374), Expect = 1e-35
Identities = 95/313 (30%), Positives = 154/313 (49%), Gaps = 28/313 (8%)
Query: 371 PEEEEEEANSYDSDEATTLGALEFSLLYDQDNSSLQCTIIKAKGLKPMDSNGL-ADPYVK 429
PE + + ++ LG L FSL Y+ + + I +A+GL MD + +DPY+K
Sbjct: 136 PESLKSSTSLTSEEKQEKLGTLFFSLEYNFERKAFVVNIKEARGLPAMDEQSMTSDPYIK 195
Query: 430 LHLLPGASKSNKLRTKTLRNTRNPIWNETLVYHGITDEDMQRKTLRISVCDEDKFGHNEF 489
+ +LP K +K++T+ LR T +P ++ET ++GI +Q L ++ D+F ++
Sbjct: 196 MTILP--EKKHKVKTRVLRKTLDPAFDETFTFYGIPYTQIQELALHFTILSFDRFSRDDI 253
Query: 490 IGETRFSLKKLKPNQRKNFNICLERVIPMKRAGTTGSARGMALYEEEQVER-VGDIEERG 548
IGE L ++ ++ G L E ++R V RG
Sbjct: 254 IGEVLIPLSGIELSE------------------------GKMLMNREIIKRNVRKSSGRG 289
Query: 549 KILVSLMYSTQQGGLIVGIIRCVHLAAMDANGYSDPFVKLWLKPDMGKKAKHKTQIKKKT 608
++L+SL Y + L V +++ HL D +G SDP+VK+ L + +K KT +KK T
Sbjct: 290 ELLISLCYQSTTNTLTVVVLKARHLPKSDVSGLSDPYVKVNLYHAKKRISKKKTHVKKCT 349
Query: 609 LNPEFNEEFFYDIKHSDLAKKSLDISVWDYDIGKSNDYIGGCQLGISAKGERLKHWYECL 668
N FNE F +DI L S++ V D + G N+ IG LG +A+G +HW E
Sbjct: 350 PNAVFNELFVFDIPCEGLEDISVEFLVLDSERGSRNEVIGQLVLGAAAEGTGGEHWKEIC 409
Query: 669 KNKDKKIERWHQL 681
++I +WH L
Sbjct: 410 DYPRRQIAKWHVL 422
>gi|28376627 synaptotagmin IX [Homo sapiens]
Length = 491
Score = 144 bits (364), Expect = 2e-34
Identities = 100/308 (32%), Positives = 152/308 (49%), Gaps = 33/308 (10%)
Query: 380 SYDSDE-----ATTLGALEFSLLYDQDNSSLQCTIIKAKGLKPMDSNGLADPYVKLHLLP 434
S D+D+ + G L F L YD D L I KA L D +G +DPYVK++LLP
Sbjct: 207 SLDNDDGRRSNSKACGKLNFILKYDCDLEQLIVKIHKAVNLPAKDFSGTSDPYVKIYLLP 266
Query: 435 GASKSNKLRTKTLRNTRNPIWNETLVYHGITDEDMQRKTLRISVCDEDKFGHNEFIGETR 494
+ K +TK R T NP+++E ++ + D++ + L SV D D+F ++ IG+
Sbjct: 267 --DRKTKHQTKVHRKTLNPVFDEVFLFP-VPYNDLEARKLHFSVYDFDRFSRHDLIGQ-- 321
Query: 495 FSLKKLKPNQRKNFNICLERVIPMKRAGTTGSARGMALYEEEQVERV-GDIEERGKILVS 553
+ ++ + + R L+++ +E V D + G+++ S
Sbjct: 322 ---------------VVVDHFLDL-----ADFPRECILWKD--IEYVTNDNVDLGELMFS 359
Query: 554 LMYSTQQGGLIVGIIRCVHLAAMDANGYSDPFVKLWLKPDMGKKAKHKTQIKKKTLNPEF 613
L Y G L + II+ +L AMD G SDP+VK+ L D + K KT K+ TLNP +
Sbjct: 360 LCYLPTAGRLTITIIKARNLKAMDITGASDPYVKVSLMCDGRRLKKRKTSTKRNTLNPVY 419
Query: 614 NEEFFYDIKHSDLAKKSLDISVWDYDIGKSNDYIGGCQLGISAKGERLKHWYECLKNKDK 673
NE +D+ ++ + L I+V DYD N+ IG CQ+G A+ HW E L K
Sbjct: 420 NEAIVFDVPPENIDQIHLSIAVMDYDRVGHNEIIGVCQVGNEAERLGRDHWSEMLSYPRK 479
Query: 674 KIERWHQL 681
I WH L
Sbjct: 480 PIAHWHSL 487
>gi|216548478 synaptotagmin XI [Homo sapiens]
Length = 431
Score = 138 bits (347), Expect = 2e-32
Identities = 98/311 (31%), Positives = 152/311 (48%), Gaps = 28/311 (9%)
Query: 374 EEEEANSYDSDEATTLGALEFSLLYDQDNSSLQCTIIKAKGLKPMDSNGL-ADPYVKLHL 432
E + + +E LG+L FS+ Y+ +L TI +A GL MD +DPY+K+ +
Sbjct: 143 ESKTTSPSSPEEDVMLGSLTFSVDYNFPKKALVVTIQEAHGLPVMDDQTQGSDPYIKMTI 202
Query: 433 LPGASKSNKLRTKTLRNTRNPIWNETLVYHGITDEDMQRKTLRISVCDEDKFGHNEFIGE 492
LP K ++++T+ LR T +P+++ET ++GI +Q L V D+F ++ IGE
Sbjct: 203 LP--DKRHRVKTRVLRKTLDPVFDETFTFYGIPYSQLQDLVLHFLVLSFDRFSRDDVIGE 260
Query: 493 TRFSLKKLKPNQRKNFNICLERVIPMKRAGTTGSARGMALYEEEQVERVGDIEERGKILV 552
L + P+ K + L R I +KR + RG++ V
Sbjct: 261 VMVPLAGVDPSTGK---VQLTRDI-IKR-------------------NIQKCISRGELQV 297
Query: 553 SLMYSTQQGGLIVGIIRCVHLAAMDANGYS-DPFVKLWLKPDMGKKAKHKTQIKKKTLNP 611
SL Y + V +++ HL MD G S +P+VK+ + + AK KT +KK TLNP
Sbjct: 298 SLSYQPVAQRMTVVVLKARHLPKMDITGLSGNPYVKVNVYYGRKRIAKKKTHVKKCTLNP 357
Query: 612 EFNEEFFYDIKHSDLAKKSLDISVWDYDIGKSNDYIGGCQLGI-SAKGERLKHWYECLKN 670
FNE F YDI L S++ V D+D N+ +G LG S +HW E ++
Sbjct: 358 IFNESFIYDIPTDLLPDISIEFLVIDFDRTTKNEVVGRLILGAHSVTASGAEHWREVCES 417
Query: 671 KDKKIERWHQL 681
K + +WH L
Sbjct: 418 PRKPVAKWHSL 428
>gi|40068038 B/K protein [Homo sapiens]
Length = 474
Score = 116 bits (290), Expect = 8e-26
Identities = 94/323 (29%), Positives = 145/323 (44%), Gaps = 44/323 (13%)
Query: 377 EANSYDSDEATT--------LGALEFSLLYDQDNSSLQCTIIKAKGLKPMDSN------- 421
++NS D D T LG L FS YD ++ L +I+A+ L P S+
Sbjct: 165 DSNSDDVDSLTDEEILSKYQLGMLHFSTQYDLLHNHLTVRVIEARDLPPPISHDGSRQDM 224
Query: 422 GLADPYVKLHLLPGASKSNKLRTKTLRNTRNPIWNETLVYHGITDEDMQRKTLRISVCDE 481
++PYVK+ LLP + N +T R T+ P++ E + I + QR+TL ++V D
Sbjct: 225 AHSNPYVKICLLP--DQKNSKQTGVKRKTQKPVFEERYTFE-IPFLEAQRRTLLLTVVDF 281
Query: 482 DKFGHNEFIGETRFSLKKLKPNQRKNFNICLERVIPMKRAGTTGSARGMALYEEEQVERV 541
DKF + IG+ L ++ G AL Q E
Sbjct: 282 DKFSRHCVIGKVSVPLCEVDL--------------------VKGGHWWKALIPSSQNE-- 319
Query: 542 GDIEERGKILVSLMYSTQQGGLIVGIIRCVHLAAMDANGYSDPFVKLWLKPDMGKKAKHK 601
E G++L+SL Y G L V +IR L D + SDPFVK+ L + K
Sbjct: 320 ---VELGELLLSLNYLPSAGRLNVDVIRAKQLLQTDVSQGSDPFVKIQLVHGLKLVKTKK 376
Query: 602 TQIKKKTLNPEFNEEFFYDIKHSDLAKKSLDISVWDYDIGKSNDYIGGCQLGISAKG-ER 660
T + T++P +NE F + + +L SL +V+ +++ SND+IG +G + G
Sbjct: 377 TSFLRGTIDPFYNESFSFKVPQEELENASLVFTVFGHNMKSSNDFIGRIVIGQYSSGPSE 436
Query: 661 LKHWYECLKNKDKKIERWHQLQN 683
HW L +E+WH L++
Sbjct: 437 TNHWRRMLNTHRTAVEQWHSLRS 459
Score = 46.6 bits (109), Expect = 8e-05
Identities = 31/115 (26%), Positives = 61/115 (53%), Gaps = 12/115 (10%)
Query: 581 YSDPFVKLWLKPDMGKKAKHKTQIKKKTLNPEFNEEFFYDIKHSDLAKKSLDISVWDYDI 640
+S+P+VK+ L PD +K +T +K+KT P F E + ++I + +++L ++V D+D
Sbjct: 226 HSNPYVKICLLPD--QKNSKQTGVKRKTQKPVFEERYTFEIPFLEAQRRTLLLTVVDFDK 283
Query: 641 GKSNDYIGG-----CQLGISAKGERLKHWYECL-KNKDKKIERWHQLQNENHVSS 689
+ IG C++ + G HW++ L + ++E L + N++ S
Sbjct: 284 FSRHCVIGKVSVPLCEVDLVKGG----HWWKALIPSSQNEVELGELLLSLNYLPS 334
>gi|244790020 synaptotagmin-like 2 isoform i [Homo sapiens]
Length = 935
Score = 114 bits (286), Expect = 2e-25
Identities = 120/521 (23%), Positives = 213/521 (40%), Gaps = 78/521 (14%)
Query: 179 EPAAPEQPAPEPKH-----PARAPARGDSEDRRGPGQKTGPDPASAPGRGNYGPPVRRAS 233
E P PA E H P++ P G S DR+ G + P P + R++
Sbjct: 455 ESVLPRSPADELSHCVEPEPSQVPG-GSSRDRQ-QGSEEEPSPVLKT--------LERSA 504
Query: 234 EARMSSSSRDSESWDHSGGAGDSSRSPAGLRRANSVQASRPAPGSVQSPAPPQPGQPGTP 293
+M S S + S D S A ++ +R A V S P QP P +
Sbjct: 505 ARKMPSKSLEDISSDSSNQAKVDNQPEELVRSAEDV-----------STVPTQPDNPFS- 552
Query: 294 GGSRPGPGPAGRFPDQKPEVAPSDPGTTAPPREERTGGVGGYPAVGAREDRMSHPSGPYS 353
PD+ ++ S P ++R + + S PS +
Sbjct: 553 ------------HPDKLKRMSKSVPAFLQDESDDRETDTASESSYQLSRHKKS-PSSLTN 599
Query: 354 QASAAAPQPAAARQPPPPEEEEEEANSYDSDEATTLGALEFSLLYDQDNSSLQCTIIKAK 413
+S++ ++ S D G ++F++ Y + L + + K
Sbjct: 600 LSSSSGMTSLSS-----VSGSVMSVYSGDFGNLEVKGNIQFAIEYVESLKELHVFVAQCK 654
Query: 414 GLKPMD-SNGLADPYVKLHLLPGASKSNKLRTKTLRNTRNPIWNETLVYHGITDEDMQRK 472
L D +DPYVK +LLP K K +T ++ T NP++NE L Y I + ++ +
Sbjct: 655 DLAAADVKKQRSDPYVKAYLLPDKGKMGKKKTLVVKKTLNPVYNEILRYK-IEKQILKTQ 713
Query: 473 TLRISVCDEDKFGHNEFIGETRFSLKKLKPNQRKNFNICLERVIPMKRAGTTGSARGMAL 532
L +S+ D F N F+GE L+ + ++N + R P+KR +AL
Sbjct: 714 KLNLSIWHRDTFKRNSFLGEVELDLETWDWDNKQNKQL---RWYPLKR-----KTAPVAL 765
Query: 533 YEEEQVERVGDIEERGKILVSLMYSTQ---------QGGLIVGIIRCVHLAAMDANGYSD 583
+ E RG++ ++L Y + G + + + C+ L + + +
Sbjct: 766 ----------EAENRGEMKLALQYVPEPVPGKKLPTTGEVHIWVKECLDLPLL-RGSHLN 814
Query: 584 PFVKLWLKPDMGKKAKHKTQIKKKTLNPEFNEEFFYD-IKHSDLAKKSLDISVWDYDIGK 642
FVK + PD +K++ KT+ KT NP FN YD + DL + ++++VWD+
Sbjct: 815 SFVKCTILPDTSRKSRQKTRAVGKTTNPIFNHTMVYDGFRPEDLMEACVELTVWDH-YKL 873
Query: 643 SNDYIGGCQLGISAKGERLKHWYECLKNKDKKIERWHQLQN 683
+N ++GG ++G G+ + + + +++ W ++ N
Sbjct: 874 TNQFLGGLRIGFGT-GKSYGTEVDWMDSTSEEVALWEKMVN 913
Score = 83.6 bits (205), Expect = 6e-16
Identities = 52/144 (36%), Positives = 75/144 (52%), Gaps = 10/144 (6%)
Query: 542 GDIEERGKILVSLMYSTQQGGLIVGIIRCVHLAAMDANGY-SDPFVKLWLKPDMGKKAKH 600
G++E +G I ++ Y L V + +C LAA D SDP+VK +L PD GK K
Sbjct: 625 GNLEVKGNIQFAIEYVESLKELHVFVAQCKDLAAADVKKQRSDPYVKAYLLPDKGKMGKK 684
Query: 601 KTQIKKKTLNPEFNEEFFYDIKHSDLAKKSLDISVWDYDIGKSNDYIGGCQLGISAKGER 660
KT + KKTLNP +NE Y I+ L + L++S+W D K N ++G +L
Sbjct: 685 KTLVVKKTLNPVYNEILRYKIEKQILKTQKLNLSIWHRDTFKRNSFLGEVELD------- 737
Query: 661 LKHWYECLKNKDKKIERWHQLQNE 684
L+ W NK K RW+ L+ +
Sbjct: 738 LETW--DWDNKQNKQLRWYPLKRK 759
Score = 31.6 bits (70), Expect = 2.6
Identities = 15/45 (33%), Positives = 29/45 (64%), Gaps = 2/45 (4%)
Query: 46 LTDEEKEIINRVIARAEKMEEMEQERIGRLVDRL--ENMRKNVAG 88
LT+EE+E I +V+ R ++ E+ER+ L +++ + KN++G
Sbjct: 7 LTEEEQEAIMKVLQRDAALKRAEEERVRHLPEKIKDDQQLKNMSG 51
>gi|244790013 synaptotagmin-like 2 isoform g [Homo sapiens]
Length = 934
Score = 114 bits (286), Expect = 2e-25
Identities = 120/521 (23%), Positives = 213/521 (40%), Gaps = 78/521 (14%)
Query: 179 EPAAPEQPAPEPKH-----PARAPARGDSEDRRGPGQKTGPDPASAPGRGNYGPPVRRAS 233
E P PA E H P++ P G S DR+ G + P P + R++
Sbjct: 454 ESVLPRSPADELSHCVEPEPSQVPG-GSSRDRQ-QGSEEEPSPVLKT--------LERSA 503
Query: 234 EARMSSSSRDSESWDHSGGAGDSSRSPAGLRRANSVQASRPAPGSVQSPAPPQPGQPGTP 293
+M S S + S D S A ++ +R A V S P QP P +
Sbjct: 504 ARKMPSKSLEDISSDSSNQAKVDNQPEELVRSAEDV-----------STVPTQPDNPFS- 551
Query: 294 GGSRPGPGPAGRFPDQKPEVAPSDPGTTAPPREERTGGVGGYPAVGAREDRMSHPSGPYS 353
PD+ ++ S P ++R + + S PS +
Sbjct: 552 ------------HPDKLKRMSKSVPAFLQDESDDRETDTASESSYQLSRHKKS-PSSLTN 598
Query: 354 QASAAAPQPAAARQPPPPEEEEEEANSYDSDEATTLGALEFSLLYDQDNSSLQCTIIKAK 413
+S++ ++ S D G ++F++ Y + L + + K
Sbjct: 599 LSSSSGMTSLSS-----VSGSVMSVYSGDFGNLEVKGNIQFAIEYVESLKELHVFVAQCK 653
Query: 414 GLKPMD-SNGLADPYVKLHLLPGASKSNKLRTKTLRNTRNPIWNETLVYHGITDEDMQRK 472
L D +DPYVK +LLP K K +T ++ T NP++NE L Y I + ++ +
Sbjct: 654 DLAAADVKKQRSDPYVKAYLLPDKGKMGKKKTLVVKKTLNPVYNEILRYK-IEKQILKTQ 712
Query: 473 TLRISVCDEDKFGHNEFIGETRFSLKKLKPNQRKNFNICLERVIPMKRAGTTGSARGMAL 532
L +S+ D F N F+GE L+ + ++N + R P+KR +AL
Sbjct: 713 KLNLSIWHRDTFKRNSFLGEVELDLETWDWDNKQNKQL---RWYPLKR-----KTAPVAL 764
Query: 533 YEEEQVERVGDIEERGKILVSLMYSTQ---------QGGLIVGIIRCVHLAAMDANGYSD 583
+ E RG++ ++L Y + G + + + C+ L + + +
Sbjct: 765 ----------EAENRGEMKLALQYVPEPVPGKKLPTTGEVHIWVKECLDLPLL-RGSHLN 813
Query: 584 PFVKLWLKPDMGKKAKHKTQIKKKTLNPEFNEEFFYD-IKHSDLAKKSLDISVWDYDIGK 642
FVK + PD +K++ KT+ KT NP FN YD + DL + ++++VWD+
Sbjct: 814 SFVKCTILPDTSRKSRQKTRAVGKTTNPIFNHTMVYDGFRPEDLMEACVELTVWDH-YKL 872
Query: 643 SNDYIGGCQLGISAKGERLKHWYECLKNKDKKIERWHQLQN 683
+N ++GG ++G G+ + + + +++ W ++ N
Sbjct: 873 TNQFLGGLRIGFGT-GKSYGTEVDWMDSTSEEVALWEKMVN 912
Score = 83.6 bits (205), Expect = 6e-16
Identities = 52/144 (36%), Positives = 75/144 (52%), Gaps = 10/144 (6%)
Query: 542 GDIEERGKILVSLMYSTQQGGLIVGIIRCVHLAAMDANGY-SDPFVKLWLKPDMGKKAKH 600
G++E +G I ++ Y L V + +C LAA D SDP+VK +L PD GK K
Sbjct: 624 GNLEVKGNIQFAIEYVESLKELHVFVAQCKDLAAADVKKQRSDPYVKAYLLPDKGKMGKK 683
Query: 601 KTQIKKKTLNPEFNEEFFYDIKHSDLAKKSLDISVWDYDIGKSNDYIGGCQLGISAKGER 660
KT + KKTLNP +NE Y I+ L + L++S+W D K N ++G +L
Sbjct: 684 KTLVVKKTLNPVYNEILRYKIEKQILKTQKLNLSIWHRDTFKRNSFLGEVELD------- 736
Query: 661 LKHWYECLKNKDKKIERWHQLQNE 684
L+ W NK K RW+ L+ +
Sbjct: 737 LETW--DWDNKQNKQLRWYPLKRK 758
Score = 32.3 bits (72), Expect = 1.5
Identities = 57/266 (21%), Positives = 100/266 (37%), Gaps = 40/266 (15%)
Query: 46 LTDEEKEIINRVIARAEKMEEMEQERIGRLVDRL--ENMRKNVAGDGVNRCILCGEQLGM 103
LT+EE+E I +V+ R ++ E+ER+ L +++ + KN++G + +
Sbjct: 7 LTEEEQEAIMKVLQRDAALKRAEEERVRHLPEKIKDDQQLKNMSGQWFYEAKAKRHRDKI 66
Query: 104 LGSACVVCEDCKKNVCTKCGVETNNRLHSVWLCKICIEQREVWKRSGA---WFFKGFPKQ 160
G+ + KK +I EQ + + +GA W
Sbjct: 67 HGADIIRASMRKKRP------------------QIAAEQSKD-RENGAKESWVNNVNKDA 107
Query: 161 VLPQPMPIKKTKPQQPVSEPAAPEQPAPEPKHPARAPARGDSEDRRGPGQKTGPDPASAP 220
LP + +P+ E AAP P+ +PA + E+ R P P+ P
Sbjct: 108 FLPPELAGVVEEPE----EDAAPASPSSSVVNPASSVIDMSQENTRKP--NVSPEKRKNP 161
Query: 221 GRGNYGPPVRRASEARMSSSSRDSESWDHSGGAGDSSRSPAGLRRANSVQASRPAPGSVQ 280
+ P E S +++ +S + G +S+ + S + S A S+Q
Sbjct: 162 FNSSKLP------EGHSSQQTKNEQSKNGRTGLFQTSKED---ELSESKEKSTVADTSIQ 212
Query: 281 SPAPPQPGQPGTPGGSR-PGPGPAGR 305
+ PG GS+ P P R
Sbjct: 213 KLEKSKQTLPGLSNGSQIKAPIPKAR 238
>gi|15011900 synaptotagmin-like 2 isoform b [Homo sapiens]
Length = 376
Score = 107 bits (268), Expect = 3e-23
Identities = 78/305 (25%), Positives = 145/305 (47%), Gaps = 33/305 (10%)
Query: 390 GALEFSLLYDQDNSSLQCTIIKAKGLKPMD-SNGLADPYVKLHLLPGASKSNKLRTKTLR 448
G ++F++ Y + L + + K L D +DPYVK +LLP K K +T ++
Sbjct: 72 GNIQFAIEYVESLKELHVFVAQCKDLAAADVKKQRSDPYVKAYLLPDKGKMGKKKTLVVK 131
Query: 449 NTRNPIWNETLVYHGITDEDMQRKTLRISVCDEDKFGHNEFIGETRFSLKKLKPNQRKNF 508
T NP++NE L Y I + ++ + L +S+ D F N F+GE L+ + ++N
Sbjct: 132 KTLNPVYNEILRYK-IEKQILKTQKLNLSIWHRDTFKRNSFLGEVELDLETWDWDNKQNK 190
Query: 509 NICLERVIPMKRAGTTGSARGMALYEEEQVERVGDIEERGKILVSLMYSTQ--------- 559
+ R P+KR +AL + E RG++ ++L Y +
Sbjct: 191 QL---RWYPLKR-----KTAPVAL----------EAENRGEMKLALQYVPEPVPGKKLPT 232
Query: 560 QGGLIVGIIRCVHLAAMDANGYSDPFVKLWLKPDMGKKAKHKTQIKKKTLNPEFNEEFFY 619
G + + + C+ L + + + FVK + PD +K++ KT+ KT NP FN Y
Sbjct: 233 TGEVHIWVKECLDLPLL-RGSHLNSFVKCTILPDTSRKSRQKTRAVGKTTNPIFNHTMVY 291
Query: 620 D-IKHSDLAKKSLDISVWDYDIGKSNDYIGGCQLGISAKGERLKHWYECLKNKDKKIERW 678
D + DL + ++++VWD+ +N ++GG ++G G+ + + + +++ W
Sbjct: 292 DGFRPEDLMEACVELTVWDH-YKLTNQFLGGLRIGFGT-GKSYGTEVDWMDSTSEEVALW 349
Query: 679 HQLQN 683
++ N
Sbjct: 350 EKMVN 354
Score = 83.6 bits (205), Expect = 6e-16
Identities = 52/144 (36%), Positives = 75/144 (52%), Gaps = 10/144 (6%)
Query: 542 GDIEERGKILVSLMYSTQQGGLIVGIIRCVHLAAMDANGY-SDPFVKLWLKPDMGKKAKH 600
G++E +G I ++ Y L V + +C LAA D SDP+VK +L PD GK K
Sbjct: 66 GNLEVKGNIQFAIEYVESLKELHVFVAQCKDLAAADVKKQRSDPYVKAYLLPDKGKMGKK 125
Query: 601 KTQIKKKTLNPEFNEEFFYDIKHSDLAKKSLDISVWDYDIGKSNDYIGGCQLGISAKGER 660
KT + KKTLNP +NE Y I+ L + L++S+W D K N ++G +L
Sbjct: 126 KTLVVKKTLNPVYNEILRYKIEKQILKTQKLNLSIWHRDTFKRNSFLGEVELD------- 178
Query: 661 LKHWYECLKNKDKKIERWHQLQNE 684
L+ W NK K RW+ L+ +
Sbjct: 179 LETW--DWDNKQNKQLRWYPLKRK 200
>gi|15011902 synaptotagmin-like 2 isoform a [Homo sapiens]
Length = 910
Score = 107 bits (268), Expect = 3e-23
Identities = 78/305 (25%), Positives = 145/305 (47%), Gaps = 33/305 (10%)
Query: 390 GALEFSLLYDQDNSSLQCTIIKAKGLKPMD-SNGLADPYVKLHLLPGASKSNKLRTKTLR 448
G ++F++ Y + L + + K L D +DPYVK +LLP K K +T ++
Sbjct: 606 GNIQFAIEYVESLKELHVFVAQCKDLAAADVKKQRSDPYVKAYLLPDKGKMGKKKTLVVK 665
Query: 449 NTRNPIWNETLVYHGITDEDMQRKTLRISVCDEDKFGHNEFIGETRFSLKKLKPNQRKNF 508
T NP++NE L Y I + ++ + L +S+ D F N F+GE L+ + ++N
Sbjct: 666 KTLNPVYNEILRYK-IEKQILKTQKLNLSIWHRDTFKRNSFLGEVELDLETWDWDNKQNK 724
Query: 509 NICLERVIPMKRAGTTGSARGMALYEEEQVERVGDIEERGKILVSLMYSTQ--------- 559
+ R P+KR +AL + E RG++ ++L Y +
Sbjct: 725 QL---RWYPLKR-----KTAPVAL----------EAENRGEMKLALQYVPEPVPGKKLPT 766
Query: 560 QGGLIVGIIRCVHLAAMDANGYSDPFVKLWLKPDMGKKAKHKTQIKKKTLNPEFNEEFFY 619
G + + + C+ L + + + FVK + PD +K++ KT+ KT NP FN Y
Sbjct: 767 TGEVHIWVKECLDLPLL-RGSHLNSFVKCTILPDTSRKSRQKTRAVGKTTNPIFNHTMVY 825
Query: 620 D-IKHSDLAKKSLDISVWDYDIGKSNDYIGGCQLGISAKGERLKHWYECLKNKDKKIERW 678
D + DL + ++++VWD+ +N ++GG ++G G+ + + + +++ W
Sbjct: 826 DGFRPEDLMEACVELTVWDH-YKLTNQFLGGLRIGFGT-GKSYGTEVDWMDSTSEEVALW 883
Query: 679 HQLQN 683
++ N
Sbjct: 884 EKMVN 888
Score = 83.6 bits (205), Expect = 6e-16
Identities = 52/144 (36%), Positives = 75/144 (52%), Gaps = 10/144 (6%)
Query: 542 GDIEERGKILVSLMYSTQQGGLIVGIIRCVHLAAMDANGY-SDPFVKLWLKPDMGKKAKH 600
G++E +G I ++ Y L V + +C LAA D SDP+VK +L PD GK K
Sbjct: 600 GNLEVKGNIQFAIEYVESLKELHVFVAQCKDLAAADVKKQRSDPYVKAYLLPDKGKMGKK 659
Query: 601 KTQIKKKTLNPEFNEEFFYDIKHSDLAKKSLDISVWDYDIGKSNDYIGGCQLGISAKGER 660
KT + KKTLNP +NE Y I+ L + L++S+W D K N ++G +L
Sbjct: 660 KTLVVKKTLNPVYNEILRYKIEKQILKTQKLNLSIWHRDTFKRNSFLGEVELD------- 712
Query: 661 LKHWYECLKNKDKKIERWHQLQNE 684
L+ W NK K RW+ L+ +
Sbjct: 713 LETW--DWDNKQNKQLRWYPLKRK 734
Score = 32.3 bits (72), Expect = 1.5
Identities = 57/266 (21%), Positives = 100/266 (37%), Gaps = 40/266 (15%)
Query: 46 LTDEEKEIINRVIARAEKMEEMEQERIGRLVDRL--ENMRKNVAGDGVNRCILCGEQLGM 103
LT+EE+E I +V+ R ++ E+ER+ L +++ + KN++G + +
Sbjct: 7 LTEEEQEAIMKVLQRDAALKRAEEERVRHLPEKIKDDQQLKNMSGQWFYEAKAKRHRDKI 66
Query: 104 LGSACVVCEDCKKNVCTKCGVETNNRLHSVWLCKICIEQREVWKRSGA---WFFKGFPKQ 160
G+ + KK +I EQ + + +GA W
Sbjct: 67 HGADIIRASMRKKRP------------------QIAAEQSKD-RENGAKESWVNNVNKDA 107
Query: 161 VLPQPMPIKKTKPQQPVSEPAAPEQPAPEPKHPARAPARGDSEDRRGPGQKTGPDPASAP 220
LP + +P+ E AAP P+ +PA + E+ R P P+ P
Sbjct: 108 FLPPELAGVVEEPE----EDAAPASPSSSVVNPASSVIDMSQENTRKP--NVSPEKRKNP 161
Query: 221 GRGNYGPPVRRASEARMSSSSRDSESWDHSGGAGDSSRSPAGLRRANSVQASRPAPGSVQ 280
+ P E S +++ +S + G +S+ + S + S A S+Q
Sbjct: 162 FNSSKLP------EGHSSQQTKNEQSKNGRTGLFQTSKED---ELSESKEKSTVADTSIQ 212
Query: 281 SPAPPQPGQPGTPGGSR-PGPGPAGR 305
+ PG GS+ P P R
Sbjct: 213 KLEKSKQTLPGLSNGSQIKAPIPKAR 238
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.313 0.132 0.402
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 34,398,052
Number of Sequences: 37866
Number of extensions: 2217944
Number of successful extensions: 31580
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 477
Number of HSP's successfully gapped in prelim test: 2234
Number of HSP's that attempted gapping in prelim test: 15512
Number of HSP's gapped (non-prelim): 11045
length of query: 690
length of database: 18,247,518
effective HSP length: 109
effective length of query: 581
effective length of database: 14,120,124
effective search space: 8203792044
effective search space used: 8203792044
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.