Guide to the Human Genome
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Search of human proteins with 4507949

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|4507949 tyrosine 3-monooxygenase/tryptophan 5-monooxygenase
activation protein, beta polypeptide [Homo sapiens]
         (246 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|4507949 tyrosine 3-monooxygenase/tryptophan 5-monooxygenase a...   484   e-137
gi|21328448 tyrosine 3-monooxygenase/tryptophan 5-monooxygenase ...   484   e-137
gi|208973244 tyrosine 3/tryptophan 5 -monooxygenase activation p...   421   e-118
gi|208973242 tyrosine 3/tryptophan 5 -monooxygenase activation p...   421   e-118
gi|208973240 tyrosine 3/tryptophan 5 -monooxygenase activation p...   421   e-118
gi|208973238 tyrosine 3/tryptophan 5 -monooxygenase activation p...   421   e-118
gi|21735625 tyrosine 3/tryptophan 5 -monooxygenase activation pr...   421   e-118
gi|4507953 tyrosine 3/tryptophan 5 -monooxygenase activation pro...   421   e-118
gi|5803227 tyrosine 3/tryptophan 5 -monooxygenase activation pro...   398   e-111
gi|21464101 tyrosine 3-monooxygenase/tryptophan 5-monooxygenase ...   360   e-100
gi|4507951 tyrosine 3-monooxygenase/tryptophan 5-monooxygenase a...   355   2e-98
gi|5454052 stratifin [Homo sapiens]                                   328   3e-90
gi|5803225 tyrosine 3/tryptophan 5 -monooxygenase activation pro...   313   9e-86
gi|50083293 coiled-coil domain containing 123 [Homo sapiens]           34   0.10 
gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens]     33   0.23 
gi|183583565 TBC1 domain family, member 3 [Homo sapiens]               33   0.30 
gi|183583567 TBC1 domain family, member 3E [Homo sapiens]              33   0.30 
gi|183583563 TBC1 domain family, member 3D [Homo sapiens]              33   0.30 
gi|226693407 TBC1 domain family, member 3H [Homo sapiens]              32   0.39 
gi|23097308 spectrin repeat containing, nuclear envelope 1 isofo...    32   0.39 
gi|149999613 TBC1 domain family, member 3B [Homo sapiens]              32   0.39 
gi|90577185 TBC1 domain family member 3C [Homo sapiens]                32   0.39 
gi|157502205 TBC1 domain family, member 3G [Homo sapiens]              32   0.39 
gi|148233596 LPS-responsive vesicle trafficking, beach and ancho...    32   0.66 
gi|207452735 epiplakin 1 [Homo sapiens]                                31   0.86 
gi|109255234 centrosomal protein 290kDa [Homo sapiens]                 31   1.1  
gi|45505178 cancer antigen 1 [Homo sapiens]                            31   1.1  
gi|46240864 sperm associated antigen 17 [Homo sapiens]                 31   1.1  
gi|4504919 keratin 8 [Homo sapiens]                                    30   1.5  
gi|4758012 clathrin heavy chain 1 [Homo sapiens]                       30   1.5  

>gi|4507949 tyrosine 3-monooxygenase/tryptophan 5-monooxygenase
           activation protein, beta polypeptide [Homo sapiens]
          Length = 246

 Score =  484 bits (1247), Expect = e-137
 Identities = 246/246 (100%), Positives = 246/246 (100%)

Query: 1   MTMDKSELVQKAKLAEQAERYDDMAAAMKAVTEQGHELSNEERNLLSVAYKNVVGARRSS 60
           MTMDKSELVQKAKLAEQAERYDDMAAAMKAVTEQGHELSNEERNLLSVAYKNVVGARRSS
Sbjct: 1   MTMDKSELVQKAKLAEQAERYDDMAAAMKAVTEQGHELSNEERNLLSVAYKNVVGARRSS 60

Query: 61  WRVISSIEQKTERNEKKQQMGKEYREKIEAELQDICNDVLELLDKYLIPNATQPESKVFY 120
           WRVISSIEQKTERNEKKQQMGKEYREKIEAELQDICNDVLELLDKYLIPNATQPESKVFY
Sbjct: 61  WRVISSIEQKTERNEKKQQMGKEYREKIEAELQDICNDVLELLDKYLIPNATQPESKVFY 120

Query: 121 LKMKGDYFRYLSEVASGDNKQTTVSNSQQAYQEAFEISKKEMQPTHPIRLGLALNFSVFY 180
           LKMKGDYFRYLSEVASGDNKQTTVSNSQQAYQEAFEISKKEMQPTHPIRLGLALNFSVFY
Sbjct: 121 LKMKGDYFRYLSEVASGDNKQTTVSNSQQAYQEAFEISKKEMQPTHPIRLGLALNFSVFY 180

Query: 181 YEILNSPEKACSLAKTAFDEAIAELDTLNEESYKDSTLIMQLLRDNLTLWTSENQGDEGD 240
           YEILNSPEKACSLAKTAFDEAIAELDTLNEESYKDSTLIMQLLRDNLTLWTSENQGDEGD
Sbjct: 181 YEILNSPEKACSLAKTAFDEAIAELDTLNEESYKDSTLIMQLLRDNLTLWTSENQGDEGD 240

Query: 241 AGEGEN 246
           AGEGEN
Sbjct: 241 AGEGEN 246


>gi|21328448 tyrosine 3-monooxygenase/tryptophan 5-monooxygenase
           activation protein, beta polypeptide [Homo sapiens]
          Length = 246

 Score =  484 bits (1247), Expect = e-137
 Identities = 246/246 (100%), Positives = 246/246 (100%)

Query: 1   MTMDKSELVQKAKLAEQAERYDDMAAAMKAVTEQGHELSNEERNLLSVAYKNVVGARRSS 60
           MTMDKSELVQKAKLAEQAERYDDMAAAMKAVTEQGHELSNEERNLLSVAYKNVVGARRSS
Sbjct: 1   MTMDKSELVQKAKLAEQAERYDDMAAAMKAVTEQGHELSNEERNLLSVAYKNVVGARRSS 60

Query: 61  WRVISSIEQKTERNEKKQQMGKEYREKIEAELQDICNDVLELLDKYLIPNATQPESKVFY 120
           WRVISSIEQKTERNEKKQQMGKEYREKIEAELQDICNDVLELLDKYLIPNATQPESKVFY
Sbjct: 61  WRVISSIEQKTERNEKKQQMGKEYREKIEAELQDICNDVLELLDKYLIPNATQPESKVFY 120

Query: 121 LKMKGDYFRYLSEVASGDNKQTTVSNSQQAYQEAFEISKKEMQPTHPIRLGLALNFSVFY 180
           LKMKGDYFRYLSEVASGDNKQTTVSNSQQAYQEAFEISKKEMQPTHPIRLGLALNFSVFY
Sbjct: 121 LKMKGDYFRYLSEVASGDNKQTTVSNSQQAYQEAFEISKKEMQPTHPIRLGLALNFSVFY 180

Query: 181 YEILNSPEKACSLAKTAFDEAIAELDTLNEESYKDSTLIMQLLRDNLTLWTSENQGDEGD 240
           YEILNSPEKACSLAKTAFDEAIAELDTLNEESYKDSTLIMQLLRDNLTLWTSENQGDEGD
Sbjct: 181 YEILNSPEKACSLAKTAFDEAIAELDTLNEESYKDSTLIMQLLRDNLTLWTSENQGDEGD 240

Query: 241 AGEGEN 246
           AGEGEN
Sbjct: 241 AGEGEN 246


>gi|208973244 tyrosine 3/tryptophan 5 -monooxygenase activation
           protein, zeta polypeptide [Homo sapiens]
          Length = 245

 Score =  421 bits (1083), Expect = e-118
 Identities = 212/242 (87%), Positives = 228/242 (94%)

Query: 3   MDKSELVQKAKLAEQAERYDDMAAAMKAVTEQGHELSNEERNLLSVAYKNVVGARRSSWR 62
           MDK+ELVQKAKLAEQAERYDDMAA MK+VTEQG ELSNEERNLLSVAYKNVVGARRSSWR
Sbjct: 1   MDKNELVQKAKLAEQAERYDDMAACMKSVTEQGAELSNEERNLLSVAYKNVVGARRSSWR 60

Query: 63  VISSIEQKTERNEKKQQMGKEYREKIEAELQDICNDVLELLDKYLIPNATQPESKVFYLK 122
           V+SSIEQKTE  EKKQQM +EYREKIE EL+DICNDVL LL+K+LIPNA+Q ESKVFYLK
Sbjct: 61  VVSSIEQKTEGAEKKQQMAREYREKIETELRDICNDVLSLLEKFLIPNASQAESKVFYLK 120

Query: 123 MKGDYFRYLSEVASGDNKQTTVSNSQQAYQEAFEISKKEMQPTHPIRLGLALNFSVFYYE 182
           MKGDY+RYL+EVA+GD+K+  V  SQQAYQEAFEISKKEMQPTHPIRLGLALNFSVFYYE
Sbjct: 121 MKGDYYRYLAEVAAGDDKKGIVDQSQQAYQEAFEISKKEMQPTHPIRLGLALNFSVFYYE 180

Query: 183 ILNSPEKACSLAKTAFDEAIAELDTLNEESYKDSTLIMQLLRDNLTLWTSENQGDEGDAG 242
           ILNSPEKACSLAKTAFDEAIAELDTL+EESYKDSTLIMQLLRDNLTLWTS+ QGDE +AG
Sbjct: 181 ILNSPEKACSLAKTAFDEAIAELDTLSEESYKDSTLIMQLLRDNLTLWTSDTQGDEAEAG 240

Query: 243 EG 244
           EG
Sbjct: 241 EG 242


>gi|208973242 tyrosine 3/tryptophan 5 -monooxygenase activation
           protein, zeta polypeptide [Homo sapiens]
          Length = 245

 Score =  421 bits (1083), Expect = e-118
 Identities = 212/242 (87%), Positives = 228/242 (94%)

Query: 3   MDKSELVQKAKLAEQAERYDDMAAAMKAVTEQGHELSNEERNLLSVAYKNVVGARRSSWR 62
           MDK+ELVQKAKLAEQAERYDDMAA MK+VTEQG ELSNEERNLLSVAYKNVVGARRSSWR
Sbjct: 1   MDKNELVQKAKLAEQAERYDDMAACMKSVTEQGAELSNEERNLLSVAYKNVVGARRSSWR 60

Query: 63  VISSIEQKTERNEKKQQMGKEYREKIEAELQDICNDVLELLDKYLIPNATQPESKVFYLK 122
           V+SSIEQKTE  EKKQQM +EYREKIE EL+DICNDVL LL+K+LIPNA+Q ESKVFYLK
Sbjct: 61  VVSSIEQKTEGAEKKQQMAREYREKIETELRDICNDVLSLLEKFLIPNASQAESKVFYLK 120

Query: 123 MKGDYFRYLSEVASGDNKQTTVSNSQQAYQEAFEISKKEMQPTHPIRLGLALNFSVFYYE 182
           MKGDY+RYL+EVA+GD+K+  V  SQQAYQEAFEISKKEMQPTHPIRLGLALNFSVFYYE
Sbjct: 121 MKGDYYRYLAEVAAGDDKKGIVDQSQQAYQEAFEISKKEMQPTHPIRLGLALNFSVFYYE 180

Query: 183 ILNSPEKACSLAKTAFDEAIAELDTLNEESYKDSTLIMQLLRDNLTLWTSENQGDEGDAG 242
           ILNSPEKACSLAKTAFDEAIAELDTL+EESYKDSTLIMQLLRDNLTLWTS+ QGDE +AG
Sbjct: 181 ILNSPEKACSLAKTAFDEAIAELDTLSEESYKDSTLIMQLLRDNLTLWTSDTQGDEAEAG 240

Query: 243 EG 244
           EG
Sbjct: 241 EG 242


>gi|208973240 tyrosine 3/tryptophan 5 -monooxygenase activation
           protein, zeta polypeptide [Homo sapiens]
          Length = 245

 Score =  421 bits (1083), Expect = e-118
 Identities = 212/242 (87%), Positives = 228/242 (94%)

Query: 3   MDKSELVQKAKLAEQAERYDDMAAAMKAVTEQGHELSNEERNLLSVAYKNVVGARRSSWR 62
           MDK+ELVQKAKLAEQAERYDDMAA MK+VTEQG ELSNEERNLLSVAYKNVVGARRSSWR
Sbjct: 1   MDKNELVQKAKLAEQAERYDDMAACMKSVTEQGAELSNEERNLLSVAYKNVVGARRSSWR 60

Query: 63  VISSIEQKTERNEKKQQMGKEYREKIEAELQDICNDVLELLDKYLIPNATQPESKVFYLK 122
           V+SSIEQKTE  EKKQQM +EYREKIE EL+DICNDVL LL+K+LIPNA+Q ESKVFYLK
Sbjct: 61  VVSSIEQKTEGAEKKQQMAREYREKIETELRDICNDVLSLLEKFLIPNASQAESKVFYLK 120

Query: 123 MKGDYFRYLSEVASGDNKQTTVSNSQQAYQEAFEISKKEMQPTHPIRLGLALNFSVFYYE 182
           MKGDY+RYL+EVA+GD+K+  V  SQQAYQEAFEISKKEMQPTHPIRLGLALNFSVFYYE
Sbjct: 121 MKGDYYRYLAEVAAGDDKKGIVDQSQQAYQEAFEISKKEMQPTHPIRLGLALNFSVFYYE 180

Query: 183 ILNSPEKACSLAKTAFDEAIAELDTLNEESYKDSTLIMQLLRDNLTLWTSENQGDEGDAG 242
           ILNSPEKACSLAKTAFDEAIAELDTL+EESYKDSTLIMQLLRDNLTLWTS+ QGDE +AG
Sbjct: 181 ILNSPEKACSLAKTAFDEAIAELDTLSEESYKDSTLIMQLLRDNLTLWTSDTQGDEAEAG 240

Query: 243 EG 244
           EG
Sbjct: 241 EG 242


>gi|208973238 tyrosine 3/tryptophan 5 -monooxygenase activation
           protein, zeta polypeptide [Homo sapiens]
          Length = 245

 Score =  421 bits (1083), Expect = e-118
 Identities = 212/242 (87%), Positives = 228/242 (94%)

Query: 3   MDKSELVQKAKLAEQAERYDDMAAAMKAVTEQGHELSNEERNLLSVAYKNVVGARRSSWR 62
           MDK+ELVQKAKLAEQAERYDDMAA MK+VTEQG ELSNEERNLLSVAYKNVVGARRSSWR
Sbjct: 1   MDKNELVQKAKLAEQAERYDDMAACMKSVTEQGAELSNEERNLLSVAYKNVVGARRSSWR 60

Query: 63  VISSIEQKTERNEKKQQMGKEYREKIEAELQDICNDVLELLDKYLIPNATQPESKVFYLK 122
           V+SSIEQKTE  EKKQQM +EYREKIE EL+DICNDVL LL+K+LIPNA+Q ESKVFYLK
Sbjct: 61  VVSSIEQKTEGAEKKQQMAREYREKIETELRDICNDVLSLLEKFLIPNASQAESKVFYLK 120

Query: 123 MKGDYFRYLSEVASGDNKQTTVSNSQQAYQEAFEISKKEMQPTHPIRLGLALNFSVFYYE 182
           MKGDY+RYL+EVA+GD+K+  V  SQQAYQEAFEISKKEMQPTHPIRLGLALNFSVFYYE
Sbjct: 121 MKGDYYRYLAEVAAGDDKKGIVDQSQQAYQEAFEISKKEMQPTHPIRLGLALNFSVFYYE 180

Query: 183 ILNSPEKACSLAKTAFDEAIAELDTLNEESYKDSTLIMQLLRDNLTLWTSENQGDEGDAG 242
           ILNSPEKACSLAKTAFDEAIAELDTL+EESYKDSTLIMQLLRDNLTLWTS+ QGDE +AG
Sbjct: 181 ILNSPEKACSLAKTAFDEAIAELDTLSEESYKDSTLIMQLLRDNLTLWTSDTQGDEAEAG 240

Query: 243 EG 244
           EG
Sbjct: 241 EG 242


>gi|21735625 tyrosine 3/tryptophan 5 -monooxygenase activation
           protein, zeta polypeptide [Homo sapiens]
          Length = 245

 Score =  421 bits (1083), Expect = e-118
 Identities = 212/242 (87%), Positives = 228/242 (94%)

Query: 3   MDKSELVQKAKLAEQAERYDDMAAAMKAVTEQGHELSNEERNLLSVAYKNVVGARRSSWR 62
           MDK+ELVQKAKLAEQAERYDDMAA MK+VTEQG ELSNEERNLLSVAYKNVVGARRSSWR
Sbjct: 1   MDKNELVQKAKLAEQAERYDDMAACMKSVTEQGAELSNEERNLLSVAYKNVVGARRSSWR 60

Query: 63  VISSIEQKTERNEKKQQMGKEYREKIEAELQDICNDVLELLDKYLIPNATQPESKVFYLK 122
           V+SSIEQKTE  EKKQQM +EYREKIE EL+DICNDVL LL+K+LIPNA+Q ESKVFYLK
Sbjct: 61  VVSSIEQKTEGAEKKQQMAREYREKIETELRDICNDVLSLLEKFLIPNASQAESKVFYLK 120

Query: 123 MKGDYFRYLSEVASGDNKQTTVSNSQQAYQEAFEISKKEMQPTHPIRLGLALNFSVFYYE 182
           MKGDY+RYL+EVA+GD+K+  V  SQQAYQEAFEISKKEMQPTHPIRLGLALNFSVFYYE
Sbjct: 121 MKGDYYRYLAEVAAGDDKKGIVDQSQQAYQEAFEISKKEMQPTHPIRLGLALNFSVFYYE 180

Query: 183 ILNSPEKACSLAKTAFDEAIAELDTLNEESYKDSTLIMQLLRDNLTLWTSENQGDEGDAG 242
           ILNSPEKACSLAKTAFDEAIAELDTL+EESYKDSTLIMQLLRDNLTLWTS+ QGDE +AG
Sbjct: 181 ILNSPEKACSLAKTAFDEAIAELDTLSEESYKDSTLIMQLLRDNLTLWTSDTQGDEAEAG 240

Query: 243 EG 244
           EG
Sbjct: 241 EG 242


>gi|4507953 tyrosine 3/tryptophan 5 -monooxygenase activation
           protein, zeta polypeptide [Homo sapiens]
          Length = 245

 Score =  421 bits (1083), Expect = e-118
 Identities = 212/242 (87%), Positives = 228/242 (94%)

Query: 3   MDKSELVQKAKLAEQAERYDDMAAAMKAVTEQGHELSNEERNLLSVAYKNVVGARRSSWR 62
           MDK+ELVQKAKLAEQAERYDDMAA MK+VTEQG ELSNEERNLLSVAYKNVVGARRSSWR
Sbjct: 1   MDKNELVQKAKLAEQAERYDDMAACMKSVTEQGAELSNEERNLLSVAYKNVVGARRSSWR 60

Query: 63  VISSIEQKTERNEKKQQMGKEYREKIEAELQDICNDVLELLDKYLIPNATQPESKVFYLK 122
           V+SSIEQKTE  EKKQQM +EYREKIE EL+DICNDVL LL+K+LIPNA+Q ESKVFYLK
Sbjct: 61  VVSSIEQKTEGAEKKQQMAREYREKIETELRDICNDVLSLLEKFLIPNASQAESKVFYLK 120

Query: 123 MKGDYFRYLSEVASGDNKQTTVSNSQQAYQEAFEISKKEMQPTHPIRLGLALNFSVFYYE 182
           MKGDY+RYL+EVA+GD+K+  V  SQQAYQEAFEISKKEMQPTHPIRLGLALNFSVFYYE
Sbjct: 121 MKGDYYRYLAEVAAGDDKKGIVDQSQQAYQEAFEISKKEMQPTHPIRLGLALNFSVFYYE 180

Query: 183 ILNSPEKACSLAKTAFDEAIAELDTLNEESYKDSTLIMQLLRDNLTLWTSENQGDEGDAG 242
           ILNSPEKACSLAKTAFDEAIAELDTL+EESYKDSTLIMQLLRDNLTLWTS+ QGDE +AG
Sbjct: 181 ILNSPEKACSLAKTAFDEAIAELDTLSEESYKDSTLIMQLLRDNLTLWTSDTQGDEAEAG 240

Query: 243 EG 244
           EG
Sbjct: 241 EG 242


>gi|5803227 tyrosine 3/tryptophan 5 -monooxygenase activation
           protein, theta polypeptide [Homo sapiens]
          Length = 245

 Score =  398 bits (1023), Expect = e-111
 Identities = 198/242 (81%), Positives = 222/242 (91%)

Query: 3   MDKSELVQKAKLAEQAERYDDMAAAMKAVTEQGHELSNEERNLLSVAYKNVVGARRSSWR 62
           M+K+EL+QKAKLAEQAERYDDMA  MKAVTEQG ELSNEERNLLSVAYKNVVG RRS+WR
Sbjct: 1   MEKTELIQKAKLAEQAERYDDMATCMKAVTEQGAELSNEERNLLSVAYKNVVGGRRSAWR 60

Query: 63  VISSIEQKTERNEKKQQMGKEYREKIEAELQDICNDVLELLDKYLIPNATQPESKVFYLK 122
           VISSIEQKT+ ++KK Q+ K+YREK+E+EL+ IC  VLELLDKYLI NAT PESKVFYLK
Sbjct: 61  VISSIEQKTDTSDKKLQLIKDYREKVESELRSICTTVLELLDKYLIANATNPESKVFYLK 120

Query: 123 MKGDYFRYLSEVASGDNKQTTVSNSQQAYQEAFEISKKEMQPTHPIRLGLALNFSVFYYE 182
           MKGDYFRYL+EVA GD+++ T+ NSQ AYQEAF+ISKKEMQPTHPIRLGLALNFSVFYYE
Sbjct: 121 MKGDYFRYLAEVACGDDRKQTIDNSQGAYQEAFDISKKEMQPTHPIRLGLALNFSVFYYE 180

Query: 183 ILNSPEKACSLAKTAFDEAIAELDTLNEESYKDSTLIMQLLRDNLTLWTSENQGDEGDAG 242
           ILN+PE AC+LAKTAFDEAIAELDTLNE+SYKDSTLIMQLLRDNLTLWTS++ G+E DA 
Sbjct: 181 ILNNPELACTLAKTAFDEAIAELDTLNEDSYKDSTLIMQLLRDNLTLWTSDSAGEECDAA 240

Query: 243 EG 244
           EG
Sbjct: 241 EG 242


>gi|21464101 tyrosine 3-monooxygenase/tryptophan 5-monooxygenase
           activation protein, gamma polypeptide [Homo sapiens]
          Length = 247

 Score =  360 bits (923), Expect = e-100
 Identities = 187/248 (75%), Positives = 212/248 (85%), Gaps = 6/248 (2%)

Query: 3   MDKSELVQKAKLAEQAERYDDMAAAMKAVTEQGHELSNEERNLLSVAYKNVVGARRSSWR 62
           +D+ +LVQKA+LAEQAERYDDMAAAMK VTE    LSNEERNLLSVAYKNVVGARRSSWR
Sbjct: 2   VDREQLVQKARLAEQAERYDDMAAAMKNVTELNEPLSNEERNLLSVAYKNVVGARRSSWR 61

Query: 63  VISSIEQKT--ERNEKKQQMGKEYREKIEAELQDICNDVLELLDKYLIPNA--TQPESKV 118
           VISSIEQKT  + NEKK +M + YREKIE EL+ +C DVL LLD YLI N   TQ ESKV
Sbjct: 62  VISSIEQKTSADGNEKKIEMVRAYREKIEKELEAVCQDVLSLLDNYLIKNCSETQYESKV 121

Query: 119 FYLKMKGDYFRYLSEVASGDNKQTTVSNSQQAYQEAFEISKKEMQPTHPIRLGLALNFSV 178
           FYLKMKGDY+RYL+EVA+G+ + T V +S++AY EA EISK+ MQPTHPIRLGLALN+SV
Sbjct: 122 FYLKMKGDYYRYLAEVATGEKRATVVESSEKAYSEAHEISKEHMQPTHPIRLGLALNYSV 181

Query: 179 FYYEILNSPEKACSLAKTAFDEAIAELDTLNEESYKDSTLIMQLLRDNLTLWTSENQGDE 238
           FYYEI N+PE+AC LAKTAFD+AIAELDTLNE+SYKDSTLIMQLLRDNLTLWTS+ Q D+
Sbjct: 182 FYYEIQNAPEQACHLAKTAFDDAIAELDTLNEDSYKDSTLIMQLLRDNLTLWTSDQQDDD 241

Query: 239 GDAGEGEN 246
           G  GEG N
Sbjct: 242 G--GEGNN 247


>gi|4507951 tyrosine 3-monooxygenase/tryptophan 5-monooxygenase
           activation protein, eta polypeptide [Homo sapiens]
          Length = 246

 Score =  355 bits (912), Expect = 2e-98
 Identities = 185/245 (75%), Positives = 211/245 (86%), Gaps = 6/245 (2%)

Query: 4   DKSELVQKAKLAEQAERYDDMAAAMKAVTEQGHELSNEERNLLSVAYKNVVGARRSSWRV 63
           D+ +L+Q+A+LAEQAERYDDMA+AMKAVTE    LSNE+RNLLSVAYKNVVGARRSSWRV
Sbjct: 3   DREQLLQRARLAEQAERYDDMASAMKAVTELNEPLSNEDRNLLSVAYKNVVGARRSSWRV 62

Query: 64  ISSIEQKT--ERNEKKQQMGKEYREKIEAELQDICNDVLELLDKYLIPNAT--QPESKVF 119
           ISSIEQKT  + NEKK +  K YREKIE EL+ +CNDVL LLDK+LI N    Q ESKVF
Sbjct: 63  ISSIEQKTMADGNEKKLEKVKAYREKIEKELETVCNDVLSLLDKFLIKNCNDFQYESKVF 122

Query: 120 YLKMKGDYFRYLSEVASGDNKQTTVSNSQQAYQEAFEISKKEMQPTHPIRLGLALNFSVF 179
           YLKMKGDY+RYL+EVASG+ K + V  S+ AY+EAFEISK++MQPTHPIRLGLALNFSVF
Sbjct: 123 YLKMKGDYYRYLAEVASGEKKNSVVEASEAAYKEAFEISKEQMQPTHPIRLGLALNFSVF 182

Query: 180 YYEILNSPEKACSLAKTAFDEAIAELDTLNEESYKDSTLIMQLLRDNLTLWTSENQGDEG 239
           YYEI N+PE+AC LAK AFD+AIAELDTLNE+SYKDSTLIMQLLRDNLTLWTS+ Q +E 
Sbjct: 183 YYEIQNAPEQACLLAKQAFDDAIAELDTLNEDSYKDSTLIMQLLRDNLTLWTSDQQDEE- 241

Query: 240 DAGEG 244
            AGEG
Sbjct: 242 -AGEG 245


>gi|5454052 stratifin [Homo sapiens]
          Length = 248

 Score =  328 bits (840), Expect = 3e-90
 Identities = 164/239 (68%), Positives = 203/239 (84%), Gaps = 2/239 (0%)

Query: 3   MDKSELVQKAKLAEQAERYDDMAAAMKAVTEQGHELSNEERNLLSVAYKNVVGARRSSWR 62
           M+++ L+QKAKLAEQAERY+DMAA MK   E+G ELS EERNLLSVAYKNVVG +R++WR
Sbjct: 1   MERASLIQKAKLAEQAERYEDMAAFMKGAVEKGEELSCEERNLLSVAYKNVVGGQRAAWR 60

Query: 63  VISSIEQKT--ERNEKKQQMGKEYREKIEAELQDICNDVLELLDKYLIPNATQPESKVFY 120
           V+SSIEQK+  E +E+K    +EYREK+E ELQ +C+ VL LLD +LI  A   ES+VFY
Sbjct: 61  VLSSIEQKSNEEGSEEKGPEVREYREKVETELQGVCDTVLGLLDSHLIKEAGDAESRVFY 120

Query: 121 LKMKGDYFRYLSEVASGDNKQTTVSNSQQAYQEAFEISKKEMQPTHPIRLGLALNFSVFY 180
           LKMKGDY+RYL+EVA+GD+K+  + +++ AYQEA +ISKKEM PT+PIRLGLALNFSVF+
Sbjct: 121 LKMKGDYYRYLAEVATGDDKKRIIDSARSAYQEAMDISKKEMPPTNPIRLGLALNFSVFH 180

Query: 181 YEILNSPEKACSLAKTAFDEAIAELDTLNEESYKDSTLIMQLLRDNLTLWTSENQGDEG 239
           YEI NSPE+A SLAKT FDEA+A+L TL+E+SYKDSTLIMQLLRDNLTLWT++N G+EG
Sbjct: 181 YEIANSPEEAISLAKTTFDEAMADLHTLSEDSYKDSTLIMQLLRDNLTLWTADNAGEEG 239


>gi|5803225 tyrosine 3/tryptophan 5 -monooxygenase activation
           protein, epsilon polypeptide [Homo sapiens]
          Length = 255

 Score =  313 bits (802), Expect = 9e-86
 Identities = 162/245 (66%), Positives = 196/245 (80%), Gaps = 6/245 (2%)

Query: 4   DKSELVQKAKLAEQAERYDDMAAAMKAVTEQGHELSNEERNLLSVAYKNVVGARRSSWRV 63
           D+ +LV +AKLAEQAERYD+M  +MK V     EL+ EERNLLSVAYKNV+GARR+SWR+
Sbjct: 3   DREDLVYQAKLAEQAERYDEMVESMKKVAGMDVELTVEERNLLSVAYKNVIGARRASWRI 62

Query: 64  ISSIEQKTERN--EKKQQMGKEYREKIEAELQDICNDVLELLDKYLIPNATQPESKVFYL 121
           ISSIEQK E    E K +M +EYR+ +E EL+ IC D+L++LDK+LIP A   ESKVFY 
Sbjct: 63  ISSIEQKEENKGGEDKLKMIREYRQMVETELKLICCDILDVLDKHLIPAANTGESKVFYY 122

Query: 122 KMKGDYFRYLSEVASGDNKQTTVSNSQQAYQEAFEISKKEMQPTHPIRLGLALNFSVFYY 181
           KMKGDY RYL+E A+G++++    NS  AY+ A +I+  E+ PTHPIRLGLALNFSVFYY
Sbjct: 123 KMKGDYHRYLAEFATGNDRKEAAENSLVAYKAASDIAMTELPPTHPIRLGLALNFSVFYY 182

Query: 182 EILNSPEKACSLAKTAFDEAIAELDTLNEESYKDSTLIMQLLRDNLTLWTSENQGDEGDA 241
           EILNSP++AC LAK AFD+AIAELDTL+EESYKDSTLIMQLLRDNLTLWTS+ QGD    
Sbjct: 183 EILNSPDRACRLAKAAFDDAIAELDTLSEESYKDSTLIMQLLRDNLTLWTSDMQGD---- 238

Query: 242 GEGEN 246
           GE +N
Sbjct: 239 GEEQN 243


>gi|50083293 coiled-coil domain containing 123 [Homo sapiens]
          Length = 783

 Score = 34.3 bits (77), Expect = 0.10
 Identities = 44/231 (19%), Positives = 93/231 (40%), Gaps = 18/231 (7%)

Query: 3   MDKSELVQKAKLAEQAERYDDMAAAMKAVTEQGHELSNEERNLLSVAYKNVVGARRSSWR 62
           + K E  ++A++ E  E+   + A  K++  + + L+ E+   L    +      R S +
Sbjct: 524 LQKEEEKERAEMEELMEKLTVLQAQKKSLLLEKNSLT-EQNKALEAELERAQKINRKSQK 582

Query: 63  VISSIEQKTERNEKKQQMGKEYREKIEAELQDICN--DVLELLDKYLIPNATQPESKVFY 120
            I  ++++ E+    +    +Y   +    ++I    D L  L K L        +KV  
Sbjct: 583 KIEVLKKQVEKAMGNEMSAHQYLANLVGLAENITQERDSLMCLAKCLESEKDGVLNKVIK 642

Query: 121 LKMKGDYFRYLSEVASGDNKQTTVSN---SQQAYQEAFEISKKEMQPTHPIRLGLALNFS 177
             ++      L E   G  KQ  +     S +  ++  + + K  Q    +R        
Sbjct: 643 SNIR---LGKLEEKVKGYKKQAALKLGDISHRLLEQQEDFAGKTAQYRQEMR-------- 691

Query: 178 VFYYEILNSPEKACSLAKTAFDEAIAELDTLNEESYKDSTLIMQLLRDNLT 228
              +++L   ++    A     E   EL+ + E +++++  I +LL+D LT
Sbjct: 692 -HLHQVLKDKQEVLDQALQQNREMEGELEVIWESTFRENRRIRELLQDTLT 741


>gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens]
          Length = 1960

 Score = 33.1 bits (74), Expect = 0.23
 Identities = 21/93 (22%), Positives = 43/93 (46%), Gaps = 11/93 (11%)

Query: 10   QKAKLAEQAERYDDMAAAMKAVTEQGHELSNEERNLLSVAYKNVVGARRSSWRVISSIEQ 69
            Q  KLA++ +  +D  A       +  E S           K++   +     +I+ +E+
Sbjct: 986  QNCKLAKEKKLLEDRIAEFTTNLTEEEEKS-----------KSLAKLKNKHEAMITDLEE 1034

Query: 70   KTERNEKKQQMGKEYREKIEAELQDICNDVLEL 102
            +  R EK++Q  ++ R K+E +  D+ + + EL
Sbjct: 1035 RLRREEKQRQELEKTRRKLEGDSTDLSDQIAEL 1067



 Score = 27.7 bits (60), Expect = 9.5
 Identities = 27/99 (27%), Positives = 45/99 (45%), Gaps = 17/99 (17%)

Query: 1    MTMDKSELVQKAKLAEQAE-RYDDMAAAMKAVTE---QGHELSNEERNLLSVAYKNVVGA 56
            M     EL  + +  E A+ R +    AMKA  E   QG +  +EE+       K +V  
Sbjct: 1537 MKTQLEELEDELQATEDAKLRLEVNLQAMKAQFERDLQGRDEQSEEKK------KQLV-- 1588

Query: 57   RRSSWRVISSIEQKTERNEKKQQMGKEYREKIEAELQDI 95
                 R +  +E + E   K++ M    R+K+E +L+D+
Sbjct: 1589 -----RQVREMEAELEDERKQRSMAVAARKKLEMDLKDL 1622


>gi|183583565 TBC1 domain family, member 3 [Homo sapiens]
          Length = 549

 Score = 32.7 bits (73), Expect = 0.30
 Identities = 21/72 (29%), Positives = 35/72 (48%), Gaps = 1/72 (1%)

Query: 37  ELSNEERNLLSVAYKNV-VGARRSSWRVISSIEQKTERNEKKQQMGKEYREKIEAELQDI 95
           E     R L+  AYK + +  R   W V+ +IE+   +N  + Q+ KE  ++    +Q I
Sbjct: 86  EKYKSSRKLIDRAYKGMPMNIRGPMWSVLLNIEEMKLKNPGRYQIMKEKGKRSSEHIQRI 145

Query: 96  CNDVLELLDKYL 107
             DV   L K++
Sbjct: 146 DRDVSGTLRKHI 157


>gi|183583567 TBC1 domain family, member 3E [Homo sapiens]
          Length = 549

 Score = 32.7 bits (73), Expect = 0.30
 Identities = 21/72 (29%), Positives = 35/72 (48%), Gaps = 1/72 (1%)

Query: 37  ELSNEERNLLSVAYKNV-VGARRSSWRVISSIEQKTERNEKKQQMGKEYREKIEAELQDI 95
           E     R L+  AYK + +  R   W V+ +IE+   +N  + Q+ KE  ++    +Q I
Sbjct: 86  EKYKSSRKLIDRAYKGMPMNIRGPMWSVLLNIEEMKLKNPGRYQIMKEKGKRSSEHIQRI 145

Query: 96  CNDVLELLDKYL 107
             DV   L K++
Sbjct: 146 DRDVSGTLRKHI 157


>gi|183583563 TBC1 domain family, member 3D [Homo sapiens]
          Length = 549

 Score = 32.7 bits (73), Expect = 0.30
 Identities = 21/72 (29%), Positives = 35/72 (48%), Gaps = 1/72 (1%)

Query: 37  ELSNEERNLLSVAYKNV-VGARRSSWRVISSIEQKTERNEKKQQMGKEYREKIEAELQDI 95
           E     R L+  AYK + +  R   W V+ +IE+   +N  + Q+ KE  ++    +Q I
Sbjct: 86  EKYKSSRKLIDRAYKGMPMNIRGPMWSVLLNIEEMKLKNPGRYQIMKEKGKRSSEHIQRI 145

Query: 96  CNDVLELLDKYL 107
             DV   L K++
Sbjct: 146 DRDVSGTLRKHI 157


>gi|226693407 TBC1 domain family, member 3H [Homo sapiens]
          Length = 549

 Score = 32.3 bits (72), Expect = 0.39
 Identities = 20/72 (27%), Positives = 35/72 (48%), Gaps = 1/72 (1%)

Query: 37  ELSNEERNLLSVAYKNV-VGARRSSWRVISSIEQKTERNEKKQQMGKEYREKIEAELQDI 95
           E     R L+  AYK + +  R   W V+ +IE+   +N  + Q+ KE  ++    +Q I
Sbjct: 86  EKYKSSRKLIDRAYKGMPMNIRGPMWSVLLNIEEMKLKNPGRYQIMKEKGKRSSEHIQRI 145

Query: 96  CNDVLELLDKYL 107
             D+   L K++
Sbjct: 146 DRDISGTLRKHM 157


>gi|23097308 spectrin repeat containing, nuclear envelope 1 isoform 2
            [Homo sapiens]
          Length = 8749

 Score = 32.3 bits (72), Expect = 0.39
 Identities = 42/193 (21%), Positives = 73/193 (37%), Gaps = 17/193 (8%)

Query: 33   EQGHEL--SNEERNLLSVAYKNVVGARRSSWRVISSIEQKTERNE--KKQQMGKEYREKI 88
            E+GH L  S  E+   +V Y     A R    +   +EQ  E     +K+ M  E    +
Sbjct: 3743 EKGHSLLKSAREKGERAVKYLEEGEAERLRKEIHDHMEQLKELTSTVRKEHMTLEKGLHL 3802

Query: 89   EAELQDICNDVLELLDKYLIPNATQPESKVFYLKMKGDYFRYLSEVASGDNKQTTVSNSQ 148
              E  D C  + + + +Y        E K+   + K    +Y S        Q TV + +
Sbjct: 3803 AKEFSDKCKALTQWIAEYQEILHVPEEPKMELYEKKAQLSKYKS-------LQQTVLSHE 3855

Query: 149  QAYQEAFEISKKEMQPTHPIRLGLALNFSVFYYEILNSPEKACSLAKTAFDEAIAELDTL 208
             + +   E  +  ++    + L   ++      ++ +  +  CS+ K   +E     D L
Sbjct: 3856 PSVKSVREKGEALLELVQDVTLKDKID------QLQSDYQDLCSIGKAMMEEIAGFEDRL 3909

Query: 209  NEESYKDSTLIMQ 221
            N    K  TLI Q
Sbjct: 3910 NNLQMKGDTLIGQ 3922


>gi|149999613 TBC1 domain family, member 3B [Homo sapiens]
          Length = 549

 Score = 32.3 bits (72), Expect = 0.39
 Identities = 20/72 (27%), Positives = 35/72 (48%), Gaps = 1/72 (1%)

Query: 37  ELSNEERNLLSVAYKNV-VGARRSSWRVISSIEQKTERNEKKQQMGKEYREKIEAELQDI 95
           E     R L+  AYK + +  R   W V+ +IE+   +N  + Q+ KE  ++    +Q I
Sbjct: 86  EKYKSSRKLIDRAYKGMPMNIRGPMWSVLLNIEEMKLKNPGRYQIMKEKGKRSSEHIQRI 145

Query: 96  CNDVLELLDKYL 107
             D+   L K++
Sbjct: 146 DRDISGTLRKHM 157


>gi|90577185 TBC1 domain family member 3C [Homo sapiens]
          Length = 549

 Score = 32.3 bits (72), Expect = 0.39
 Identities = 20/72 (27%), Positives = 35/72 (48%), Gaps = 1/72 (1%)

Query: 37  ELSNEERNLLSVAYKNV-VGARRSSWRVISSIEQKTERNEKKQQMGKEYREKIEAELQDI 95
           E     R L+  AYK + +  R   W V+ +IE+   +N  + Q+ KE  ++    +Q I
Sbjct: 86  EKYKSSRKLIDRAYKGMPMNIRGPMWSVLLNIEEMKLKNPGRYQIMKEKGKRSSEHIQRI 145

Query: 96  CNDVLELLDKYL 107
             D+   L K++
Sbjct: 146 DRDISGTLRKHM 157


>gi|157502205 TBC1 domain family, member 3G [Homo sapiens]
          Length = 549

 Score = 32.3 bits (72), Expect = 0.39
 Identities = 20/72 (27%), Positives = 35/72 (48%), Gaps = 1/72 (1%)

Query: 37  ELSNEERNLLSVAYKNV-VGARRSSWRVISSIEQKTERNEKKQQMGKEYREKIEAELQDI 95
           E     R L+  AYK + +  R   W V+ +IE+   +N  + Q+ KE  ++    +Q I
Sbjct: 86  EKYKSSRKLIDRAYKGMPMNIRGPMWSVLLNIEEMKLKNPGRYQIMKEKGKRSSEHIQRI 145

Query: 96  CNDVLELLDKYL 107
             D+   L K++
Sbjct: 146 DRDISGTLRKHM 157


>gi|148233596 LPS-responsive vesicle trafficking, beach and anchor
           containing [Homo sapiens]
          Length = 2863

 Score = 31.6 bits (70), Expect = 0.66
 Identities = 23/78 (29%), Positives = 43/78 (55%), Gaps = 13/78 (16%)

Query: 61  WRVISSIEQKTERNEK--------KQQMGKEYREKIEAELQDICNDVLELLDKYLIPNAT 112
           W + ++I +K+ RN +        ++ +GK   EK++  + D+  D+L +L  Y   N T
Sbjct: 111 WSMFTAILKKSIRNLQVCTEVGLVEKVLGKI--EKVDNMIADLLVDMLGVLASY---NLT 165

Query: 113 QPESKVFYLKMKGDYFRY 130
             E K+F+ K++GD  R+
Sbjct: 166 VRELKLFFSKLQGDKGRW 183


>gi|207452735 epiplakin 1 [Homo sapiens]
          Length = 5090

 Score = 31.2 bits (69), Expect = 0.86
 Identities = 29/108 (26%), Positives = 48/108 (44%), Gaps = 13/108 (12%)

Query: 7    ELVQKAKLAEQAERYDDMAAAM----KAVTEQGHELSNEERNLLSVAYKNVV-----GAR 57
            E V   +L E+    +D    +    KA  +  H + +E R  L      +      G +
Sbjct: 2061 EKVSYRELQERCRPQEDTGWVLFPVNKAARDSEH-IDDETRRALEAEQVEITVGRFRGQK 2119

Query: 58   RSSWRVISSIEQKTERNEKKQQMGKEYREKIEAELQDICNDVLELLDK 105
             + W +++S E  TE  EKK Q+ + YR      LQ +   +LEL++K
Sbjct: 2120 PTLWALLNS-EYVTE--EKKLQLVRMYRTHTRRALQTVAQLILELIEK 2164


>gi|109255234 centrosomal protein 290kDa [Homo sapiens]
          Length = 2479

 Score = 30.8 bits (68), Expect = 1.1
 Identities = 48/261 (18%), Positives = 94/261 (36%), Gaps = 53/261 (20%)

Query: 13  KLAEQAERYDDMAAAMKAVTEQGHELSNE---------------ERNLLSVAYKNVVGAR 57
           KL E  E    +   MK + +   E+  +               ER + ++  KN  G  
Sbjct: 636 KLKELVEENKQLEEGMKEILQAIKEMQKDPDVKGGETSLIIPSLERLVNAIESKNAEGIF 695

Query: 58  RSSWRVISSIEQKTERNEKKQQMGKEYREKIEAELQDICNDVLEL--LDKYL-------- 107
            +S  + + ++Q T RNE+ +Q  +E R++     Q +    L++  L+K          
Sbjct: 696 DASLHLKAQVDQLTGRNEELRQELRESRKEAINYSQQLAKANLKIDHLEKETSLLRQSEG 755

Query: 108 ---------IPNATQPESKVFYLKMKGDYFRYLSEVASGDNKQTTVSNSQQAYQEAFEIS 158
                    +P+   P S              L E+ + + K   + +S + Y   F + 
Sbjct: 756 SNVVFKGIDLPDGIAPSSASIINSQNEYLIHLLQELENKEKKLKNLEDSLEDYNRKFAVI 815

Query: 159 KKEMQPTHPIRLGLALNFSVFYYEILNSPEKACSLAKTAFDEA-----IAELDTLNEESY 213
           + +               S+ Y E L+  E   + +KT  +E        + D +  + Y
Sbjct: 816 RHQQ--------------SLLYKEYLSEKETWKTESKTIKEEKRKLEDQVQQDAIKVKEY 861

Query: 214 KDSTLIMQLLRDNLTLWTSEN 234
            +    +Q+  D +    +EN
Sbjct: 862 NNLLNALQMDSDEMKKILAEN 882


>gi|45505178 cancer antigen 1 [Homo sapiens]
          Length = 641

 Score = 30.8 bits (68), Expect = 1.1
 Identities = 33/187 (17%), Positives = 78/187 (41%), Gaps = 8/187 (4%)

Query: 36  HELSNEERNLLSVAYKNVVGARRSSWRVISSIEQKTERNEKKQQMGKEYREKIEAELQDI 95
           ++L      L+   YK ++  +  + + + ++E+     +K  Q  +  +E ++ + + I
Sbjct: 219 NKLKENVEELIEDKYK-IILEKNDTKKTLQNLEEVLANTQKHLQESRNDKEMLQLQFKKI 277

Query: 96  CNDVLELLDKYLIPNATQPESKVFYLKMKGDYFRYLSEVASGDNKQTTVSNSQQAYQEAF 155
             + + L ++Y+     + +S   YL+M     +   EV   +  Q      ++A   A 
Sbjct: 278 KANYVCLQERYMTEMQQKNKSVSQYLEMDKTLSKKEEEV---ERLQQLKKELEKATASAL 334

Query: 156 EISKKEMQPTHPIRLGLALNFSVFYYEILNSPEKACSLAKTAFDEAIAELDTLNEESYKD 215
           ++ K+E +      L L   F     E L   +K     K+  ++ + ++  L   S  +
Sbjct: 335 DLLKREKEAQEQEFLSLQEEFQKLEKENLEERQK----LKSRLEKLLTQVRNLQFMSENE 390

Query: 216 STLIMQL 222
            T  ++L
Sbjct: 391 RTKNIKL 397


>gi|46240864 sperm associated antigen 17 [Homo sapiens]
          Length = 2223

 Score = 30.8 bits (68), Expect = 1.1
 Identities = 26/118 (22%), Positives = 53/118 (44%), Gaps = 12/118 (10%)

Query: 3    MDKSELVQKAKLAEQAERYDDMAAAMKAVTEQGHELSNEERNLLSVAYKNVVGARRSSWR 62
            + K+E+  + K  E+ +    +  ++KA  E+ H L+ EER L         G      +
Sbjct: 912  ISKTEISDQEKEKEKEKIPFILEGSLKAWKEEQHRLAEEER-LREEKKAEKKGKEAGKKK 970

Query: 63   VISSIEQKTERNEKKQQMGKEYREKIEAELQDICNDVLELLDKYLIPNATQPESKVFY 120
               + E++  R+ KK+   KE  ++ + ++Q++  +           +  QPE K+ Y
Sbjct: 971  GKDNAEKEDSRSLKKKSPYKEKSKEEQVKIQEVTEE-----------SPHQPEPKITY 1017


>gi|4504919 keratin 8 [Homo sapiens]
          Length = 483

 Score = 30.4 bits (67), Expect = 1.5
 Identities = 41/164 (25%), Positives = 71/164 (43%), Gaps = 7/164 (4%)

Query: 1   MTMDKSE-LVQKAKLAEQAERYDDMAAAMKAVTEQGHELSNEERNLLSVAYKNVVGARRS 59
           ++MD S  L   + +AE   +Y+D+A   +A  E  +++  EE  L S+A K+    RR+
Sbjct: 246 LSMDNSRSLDMDSIIAEVKAQYEDIANRSRAEAESMYQIKYEE--LQSLAGKHGDDLRRT 303

Query: 60  SWRVISSIEQKTERNEKKQQMGKEYREKIEAELQDICNDVLELLDKYLIPNATQPESKVF 119
               IS + +   R + + +  K  R  +EA + D      EL  K    NA   E +  
Sbjct: 304 KTE-ISEMNRNISRLQAEIEGLKGQRASLEAAIAD-AEQRGELAIK--DANAKLSELEAA 359

Query: 120 YLKMKGDYFRYLSEVASGDNKQTTVSNSQQAYQEAFEISKKEMQ 163
             + K D  R L E     N +  +      Y++  E  +  ++
Sbjct: 360 LQRAKQDMARQLREYQELMNVKLALDIEIATYRKLLEGEESRLE 403


>gi|4758012 clathrin heavy chain 1 [Homo sapiens]
          Length = 1675

 Score = 30.4 bits (67), Expect = 1.5
 Identities = 27/124 (21%), Positives = 56/124 (45%), Gaps = 13/124 (10%)

Query: 94   DICNDVLELLDKYLIPNATQPESK-----VFYLKMKGDYFRYLSEVASGDNKQ----TTV 144
            D+ N+++ELL+K ++ N+   E +     +    +K D  R +  +   DN        +
Sbjct: 999  DLPNELIELLEKIVLDNSVFSEHRNLQNLLILTAIKADRTRVMEYINRLDNYDAPDIANI 1058

Query: 145  SNSQQAYQEAFEISKKEMQPTHPIRLGLA----LNFSVFYYEILNSPEKACSLAKTAFDE 200
            + S + ++EAF I +K    T  +++ +     L+ +  + E  N P     LAK    +
Sbjct: 1059 AISNELFEEAFAIFRKFDVNTSAVQVLIEHIGNLDRAYEFAERCNEPAVWSQLAKAQLQK 1118

Query: 201  AIAE 204
             + +
Sbjct: 1119 GMVK 1122


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.309    0.126    0.339 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 8,205,247
Number of Sequences: 37866
Number of extensions: 322924
Number of successful extensions: 1404
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 22
Number of HSP's successfully gapped in prelim test: 71
Number of HSP's that attempted gapping in prelim test: 1347
Number of HSP's gapped (non-prelim): 122
length of query: 246
length of database: 18,247,518
effective HSP length: 100
effective length of query: 146
effective length of database: 14,460,918
effective search space: 2111294028
effective search space used: 2111294028
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 60 (27.7 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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