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Search of human proteins with 4507807
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4507807 uncoupling protein 3 isoform UCP3L [Homo sapiens]
(312 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4507807 uncoupling protein 3 isoform UCP3L [Homo sapiens] 628 e-180
gi|13259546 uncoupling protein 3 isoform UCP3S [Homo sapiens] 555 e-158
gi|13259541 uncoupling protein 2 [Homo sapiens] 445 e-125
gi|11225256 uncoupling protein 1 [Homo sapiens] 353 1e-97
gi|4507009 solute carrier family 25, member 14 isoform UCP5L [Ho... 196 2e-50
gi|13259543 solute carrier family 25, member 14 isoform UCP5S [H... 196 2e-50
gi|58197562 solute carrier family 25, member 30 [Homo sapiens] 196 2e-50
gi|108860679 solute carrier family 25, member 27 [Homo sapiens] 181 1e-45
gi|21361114 solute carrier family 25 (mitochondrial carrier; oxo... 163 2e-40
gi|20149598 solute carrier family 25 (mitochondrial carrier; dic... 160 1e-39
gi|46409330 solute carrier family 25, member 34 [Homo sapiens] 122 3e-28
gi|46397377 chromosome 14 open reading frame 68 [Homo sapiens] 100 1e-21
gi|116235462 solute carrier family 25, member 45 isoform a [Homo... 99 4e-21
gi|156071462 solute carrier family 25, member A6 [Homo sapiens] 99 5e-21
gi|4557403 carnitine/acylcarnitine translocase [Homo sapiens] 96 3e-20
gi|21389315 solute carrier family 25 (mitochondrial carrier; cit... 95 9e-20
gi|156071459 solute carrier family 25, member 5 [Homo sapiens] 94 1e-19
gi|41462412 solute carrier family 25, member 35 [Homo sapiens] 93 3e-19
gi|55749577 solute carrier family 25 (mitochondrial carrier; ade... 91 1e-18
gi|13775208 solute carrier family 25 (mitochondrial carrier; ade... 91 1e-18
gi|186928856 solute carrier family 25, member 19 [Homo sapiens] 89 5e-18
gi|186928860 solute carrier family 25, member 19 [Homo sapiens] 89 5e-18
gi|186928858 solute carrier family 25, member 19 [Homo sapiens] 89 5e-18
gi|13375983 mitochondrial glutamate carrier 1 [Homo sapiens] 87 1e-17
gi|239755176 PREDICTED: similar to solute carrier family 25, mem... 87 2e-17
gi|239755174 PREDICTED: similar to solute carrier family 25, mem... 87 2e-17
gi|56699407 solute carrier family 25, member 25 isoform c [Homo ... 87 2e-17
gi|56699401 solute carrier family 25, member 25 isoform a [Homo ... 87 2e-17
gi|56699405 solute carrier family 25, member 25 isoform d [Homo ... 87 2e-17
gi|13899342 solute carrier [Homo sapiens] 87 2e-17
>gi|4507807 uncoupling protein 3 isoform UCP3L [Homo sapiens]
Length = 312
Score = 628 bits (1620), Expect = e-180
Identities = 312/312 (100%), Positives = 312/312 (100%)
Query: 1 MVGLKPSDVPPTMAVKFLGAGTAACFADLVTFPLDTAKVRLQIQGENQAVQTARLVQYRG 60
MVGLKPSDVPPTMAVKFLGAGTAACFADLVTFPLDTAKVRLQIQGENQAVQTARLVQYRG
Sbjct: 1 MVGLKPSDVPPTMAVKFLGAGTAACFADLVTFPLDTAKVRLQIQGENQAVQTARLVQYRG 60
Query: 61 VLGTILTMVRTEGPCSPYNGLVAGLQRQMSFASIRIGLYDSVKQVYTPKGADNSSLTTRI 120
VLGTILTMVRTEGPCSPYNGLVAGLQRQMSFASIRIGLYDSVKQVYTPKGADNSSLTTRI
Sbjct: 61 VLGTILTMVRTEGPCSPYNGLVAGLQRQMSFASIRIGLYDSVKQVYTPKGADNSSLTTRI 120
Query: 121 LAGCTTGAMAVTCAQPTDVVKVRFQASIHLGPSRSDRKYSGTMDAYRTIAREEGVRGLWK 180
LAGCTTGAMAVTCAQPTDVVKVRFQASIHLGPSRSDRKYSGTMDAYRTIAREEGVRGLWK
Sbjct: 121 LAGCTTGAMAVTCAQPTDVVKVRFQASIHLGPSRSDRKYSGTMDAYRTIAREEGVRGLWK 180
Query: 181 GTLPNIMRNAIVNCAEVVTYDILKEKLLDYHLLTDNFPCHFVSAFGAGFCATVVASPVDV 240
GTLPNIMRNAIVNCAEVVTYDILKEKLLDYHLLTDNFPCHFVSAFGAGFCATVVASPVDV
Sbjct: 181 GTLPNIMRNAIVNCAEVVTYDILKEKLLDYHLLTDNFPCHFVSAFGAGFCATVVASPVDV 240
Query: 241 VKTRYMNSPPGQYFSPLDCMIKMVAQEGPTAFYKGFTPSFLRLGSWNVVMFVTYEQLKRA 300
VKTRYMNSPPGQYFSPLDCMIKMVAQEGPTAFYKGFTPSFLRLGSWNVVMFVTYEQLKRA
Sbjct: 241 VKTRYMNSPPGQYFSPLDCMIKMVAQEGPTAFYKGFTPSFLRLGSWNVVMFVTYEQLKRA 300
Query: 301 LMKVQMLRESPF 312
LMKVQMLRESPF
Sbjct: 301 LMKVQMLRESPF 312
>gi|13259546 uncoupling protein 3 isoform UCP3S [Homo sapiens]
Length = 275
Score = 555 bits (1430), Expect = e-158
Identities = 275/275 (100%), Positives = 275/275 (100%)
Query: 1 MVGLKPSDVPPTMAVKFLGAGTAACFADLVTFPLDTAKVRLQIQGENQAVQTARLVQYRG 60
MVGLKPSDVPPTMAVKFLGAGTAACFADLVTFPLDTAKVRLQIQGENQAVQTARLVQYRG
Sbjct: 1 MVGLKPSDVPPTMAVKFLGAGTAACFADLVTFPLDTAKVRLQIQGENQAVQTARLVQYRG 60
Query: 61 VLGTILTMVRTEGPCSPYNGLVAGLQRQMSFASIRIGLYDSVKQVYTPKGADNSSLTTRI 120
VLGTILTMVRTEGPCSPYNGLVAGLQRQMSFASIRIGLYDSVKQVYTPKGADNSSLTTRI
Sbjct: 61 VLGTILTMVRTEGPCSPYNGLVAGLQRQMSFASIRIGLYDSVKQVYTPKGADNSSLTTRI 120
Query: 121 LAGCTTGAMAVTCAQPTDVVKVRFQASIHLGPSRSDRKYSGTMDAYRTIAREEGVRGLWK 180
LAGCTTGAMAVTCAQPTDVVKVRFQASIHLGPSRSDRKYSGTMDAYRTIAREEGVRGLWK
Sbjct: 121 LAGCTTGAMAVTCAQPTDVVKVRFQASIHLGPSRSDRKYSGTMDAYRTIAREEGVRGLWK 180
Query: 181 GTLPNIMRNAIVNCAEVVTYDILKEKLLDYHLLTDNFPCHFVSAFGAGFCATVVASPVDV 240
GTLPNIMRNAIVNCAEVVTYDILKEKLLDYHLLTDNFPCHFVSAFGAGFCATVVASPVDV
Sbjct: 181 GTLPNIMRNAIVNCAEVVTYDILKEKLLDYHLLTDNFPCHFVSAFGAGFCATVVASPVDV 240
Query: 241 VKTRYMNSPPGQYFSPLDCMIKMVAQEGPTAFYKG 275
VKTRYMNSPPGQYFSPLDCMIKMVAQEGPTAFYKG
Sbjct: 241 VKTRYMNSPPGQYFSPLDCMIKMVAQEGPTAFYKG 275
Score = 60.1 bits (144), Expect = 2e-09
Identities = 47/205 (22%), Positives = 77/205 (37%), Gaps = 9/205 (4%)
Query: 115 SLTTRILAGCTTGAMAVTCAQPTDVVKVRFQASIHLGPSRSDR--KYSGTMDAYRTIARE 172
++ + L T A P D KVR Q ++ R +Y G + T+ R
Sbjct: 12 TMAVKFLGAGTAACFADLVTFPLDTAKVRLQIQGENQAVQTARLVQYRGVLGTILTMVRT 71
Query: 173 EGVRGLWKGTLPNIMRNAIVNCAEVVTYDILKEKLLDYHLLTDNFPCHFVSAFGAGFCAT 232
EG + G + + R + YD +K+ + ++ G A
Sbjct: 72 EGPCSPYNGLVAGLQRQMSFASIRIGLYDSVKQVYTPKGADNSSLTTRILAGCTTGAMAV 131
Query: 233 VVASPVDVVKTRYMNS-------PPGQYFSPLDCMIKMVAQEGPTAFYKGFTPSFLRLGS 285
A P DVVK R+ S +Y +D + +EG +KG P+ +R
Sbjct: 132 TCAQPTDVVKVRFQASIHLGPSRSDRKYSGTMDAYRTIAREEGVRGLWKGTLPNIMRNAI 191
Query: 286 WNVVMFVTYEQLKRALMKVQMLRES 310
N VTY+ LK L+ +L ++
Sbjct: 192 VNCAEVVTYDILKEKLLDYHLLTDN 216
>gi|13259541 uncoupling protein 2 [Homo sapiens]
Length = 309
Score = 445 bits (1144), Expect = e-125
Identities = 226/313 (72%), Positives = 257/313 (82%), Gaps = 5/313 (1%)
Query: 1 MVGLKPSDVPPTMAVKFLGAGTAACFADLVTFPLDTAKVRLQIQGENQA-VQTARLVQYR 59
MVG K +DVPPT VKFLGAGTAAC ADL+TFPLDTAKVRLQIQGE+Q V+ QYR
Sbjct: 1 MVGFKATDVPPTATVKFLGAGTAACIADLITFPLDTAKVRLQIQGESQGPVRATASAQYR 60
Query: 60 GVLGTILTMVRTEGPCSPYNGLVAGLQRQMSFASIRIGLYDSVKQVYTPKGADNSSLTTR 119
GV+GTILTMVRTEGP S YNGLVAGLQRQMSFAS+RIGLYDSVKQ YT KG++++S+ +R
Sbjct: 61 GVMGTILTMVRTEGPRSLYNGLVAGLQRQMSFASVRIGLYDSVKQFYT-KGSEHASIGSR 119
Query: 120 ILAGCTTGAMAVTCAQPTDVVKVRFQASIHLGPSRSDRKYSGTMDAYRTIAREEGVRGLW 179
+LAG TTGA+AV AQPTDVVKVRFQA G R+Y T++AY+TIAREEG RGLW
Sbjct: 120 LLAGSTTGALAVAVAQPTDVVKVRFQAQARAG---GGRRYQSTVNAYKTIAREEGFRGLW 176
Query: 180 KGTLPNIMRNAIVNCAEVVTYDILKEKLLDYHLLTDNFPCHFVSAFGAGFCATVVASPVD 239
KGT PN+ RNAIVNCAE+VTYD++K+ LL +L+TD+ PCHF SAFGAGFC TV+ASPVD
Sbjct: 177 KGTSPNVARNAIVNCAELVTYDLIKDALLKANLMTDDLPCHFTSAFGAGFCTTVIASPVD 236
Query: 240 VVKTRYMNSPPGQYFSPLDCMIKMVAQEGPTAFYKGFTPSFLRLGSWNVVMFVTYEQLKR 299
VVKTRYMNS GQY S C + M+ +EGP AFYKGF PSFLRLGSWNVVMFVTYEQLKR
Sbjct: 237 VVKTRYMNSALGQYSSAGHCALTMLQKEGPRAFYKGFMPSFLRLGSWNVVMFVTYEQLKR 296
Query: 300 ALMKVQMLRESPF 312
ALM RE+PF
Sbjct: 297 ALMAACTSREAPF 309
>gi|11225256 uncoupling protein 1 [Homo sapiens]
Length = 307
Score = 353 bits (906), Expect = 1e-97
Identities = 178/303 (58%), Positives = 225/303 (74%), Gaps = 5/303 (1%)
Query: 1 MVGLKPSDVPPTMAVKFLGAGTAACFADLVTFPLDTAKVRLQIQGENQAVQTARLVQYRG 60
M GL SDV PT+ V+ AG AAC AD++TFPLDTAKVRLQ+QGE T+ +++Y+G
Sbjct: 1 MGGLTASDVHPTLGVQLFSAGIAACLADVITFPLDTAKVRLQVQGE---CPTSSVIRYKG 57
Query: 61 VLGTILTMVRTEGPCSPYNGLVAGLQRQMSFASIRIGLYDSVKQVYTPKGADNSSLTTRI 120
VLGTI +V+TEG Y+GL AGLQRQ+S AS+RIGLYD+V++ T SL ++I
Sbjct: 58 VLGTITAVVKTEGRMKLYSGLPAGLQRQISSASLRIGLYDTVQEFLTAGKETAPSLGSKI 117
Query: 121 LAGCTTGAMAVTCAQPTDVVKVRFQASIHLGPSRSDRKYSGTMDAYRTIAREEGVRGLWK 180
LAG TTG +AV QPT+VVKVR QA HL + +Y+GT +AYR IA EG+ GLWK
Sbjct: 118 LAGLTTGGVAVFIGQPTEVVKVRLQAQSHLHGIKP--RYTGTYNAYRIIATTEGLTGLWK 175
Query: 181 GTLPNIMRNAIVNCAEVVTYDILKEKLLDYHLLTDNFPCHFVSAFGAGFCATVVASPVDV 240
GT PN+MR+ I+NC E+VTYD++KE + ++L D+ PCH VSA AGFCAT ++SPVDV
Sbjct: 176 GTTPNLMRSVIINCTELVTYDLMKEAFVKNNILADDVPCHLVSALIAGFCATAMSSPVDV 235
Query: 241 VKTRYMNSPPGQYFSPLDCMIKMVAQEGPTAFYKGFTPSFLRLGSWNVVMFVTYEQLKRA 300
VKTR++NSPPGQY S +C +K+ EGPTAF+KG PSFLRLGSWNV+MFV +EQLKR
Sbjct: 236 VKTRFINSPPGQYKSVPNCAMKVFTNEGPTAFFKGLVPSFLRLGSWNVIMFVCFEQLKRE 295
Query: 301 LMK 303
L K
Sbjct: 296 LSK 298
Score = 59.3 bits (142), Expect = 4e-09
Identities = 45/200 (22%), Positives = 79/200 (39%), Gaps = 6/200 (3%)
Query: 115 SLTTRILAGCTTGAMAVTCAQPTDVVKVRFQASIHLGPSRSDRKYSGTMDAYRTIAREEG 174
+L ++ + +A P D KVR Q P+ S +Y G + + + EG
Sbjct: 12 TLGVQLFSAGIAACLADVITFPLDTAKVRLQVQGEC-PTSSVIRYKGVLGTITAVVKTEG 70
Query: 175 VRGLWKGTLPNIMRNAIVNCAEVVTYDILKEKLLDYHLLTDNFPCHFVSAFGAGFCATVV 234
L+ G + R + YD ++E L + ++ G A +
Sbjct: 71 RMKLYSGLPAGLQRQISSASLRIGLYDTVQEFLTAGKETAPSLGSKILAGLTTGGVAVFI 130
Query: 235 ASPVDVVKTR-----YMNSPPGQYFSPLDCMIKMVAQEGPTAFYKGFTPSFLRLGSWNVV 289
P +VVK R +++ +Y + + EG T +KG TP+ +R N
Sbjct: 131 GQPTEVVKVRLQAQSHLHGIKPRYTGTYNAYRIIATTEGLTGLWKGTTPNLMRSVIINCT 190
Query: 290 MFVTYEQLKRALMKVQMLRE 309
VTY+ +K A +K +L +
Sbjct: 191 ELVTYDLMKEAFVKNNILAD 210
>gi|4507009 solute carrier family 25, member 14 isoform UCP5L [Homo
sapiens]
Length = 325
Score = 196 bits (499), Expect = 2e-50
Identities = 108/289 (37%), Positives = 170/289 (58%), Gaps = 16/289 (5%)
Query: 17 FLGAGTAACFADLVTFPLDTAKVRLQIQGENQAVQTARLVQYRGVLGTILTMVRTEGPCS 76
F+ G A+ A+ TFP+D K RLQ+QG++ + ++YRG+ + + + EG +
Sbjct: 44 FVYGGLASIVAEFGTFPVDLTKTRLQVQGQSIDARFKE-IKYRGMFHALFRICKEEGVLA 102
Query: 77 PYNGLVAGLQRQMSFASIRIGLYDSVKQVYTPKGADNSSLTTRILAGCTTGAMAVTCAQP 136
Y+G+ L RQ S+ +I+IG+Y S+K+++ + ++ +L ++ G +G ++ T A P
Sbjct: 103 LYSGIAPALLRQASYGTIKIGIYQSLKRLFVER-LEDETLLINMICGVVSGVISSTIANP 161
Query: 137 TDVVKVRFQASIHLGPSRSDRKYSGTM-DAYRTIAREEGVRGLWKGTLPNIMRNAIVNCA 195
TDV+K+R QA L + G+M ++ I ++EG RGLW+G +P R AIV
Sbjct: 162 TDVLKIRMQAQGSL--------FQGSMIGSFIDIYQQEGTRGLWRGVVPTAQRAAIVVGV 213
Query: 196 EVVTYDILKEKLLDYHLLTDNFPCHFVSAFGAGFCATVVASPVDVVKTRYMNSPP----- 250
E+ YDI K+ L+ ++ D HFVS+F G + ++PVDVV+TR MN
Sbjct: 214 ELPVYDITKKHLILSGMMGDTILTHFVSSFTCGLAGALASNPVDVVRTRMMNQRAIVGHV 273
Query: 251 GQYFSPLDCMIKMVAQEGPTAFYKGFTPSFLRLGSWNVVMFVTYEQLKR 299
Y +D ++KM EG A YKGF P++LRLG WN++ F+TYEQLKR
Sbjct: 274 DLYKGTVDGILKMWKHEGFFALYKGFWPNWLRLGPWNIIFFITYEQLKR 322
Score = 63.2 bits (152), Expect = 3e-10
Identities = 47/197 (23%), Positives = 83/197 (42%), Gaps = 19/197 (9%)
Query: 12 TMAVKFLGAGTAACFADLVTFPLDTAKVRLQIQGENQAVQTARLVQYRGVLGTILTMVRT 71
T+ + + + + + P D K+R+Q QG + ++G+ + + +
Sbjct: 140 TLLINMICGVVSGVISSTIANPTDVLKIRMQAQGS---------LFQGSMIGSFIDIYQQ 190
Query: 72 EGPCSPYNGLVAGLQRQMSFASIRIGLYDSVKQVYTPKGADNSSLTTRILAGCTTGAMAV 131
EG + G+V QR + + +YD K+ G ++ T ++ T G
Sbjct: 191 EGTRGLWRGVVPTAQRAAIVVGVELPVYDITKKHLILSGMMGDTILTHFVSSFTCGLAGA 250
Query: 132 TCAQPTDVVKVRF--QASI--HLGPSRSDRKYSGTMDAYRTIAREEGVRGLWKGTLPNIM 187
+ P DVV+ R Q +I H+ Y GT+D + + EG L+KG PN +
Sbjct: 251 LASNPVDVVRTRMMNQRAIVGHVD------LYKGTVDGILKMWKHEGFFALYKGFWPNWL 304
Query: 188 RNAIVNCAEVVTYDILK 204
R N +TY+ LK
Sbjct: 305 RLGPWNIIFFITYEQLK 321
Score = 37.7 bits (86), Expect = 0.013
Identities = 25/91 (27%), Positives = 39/91 (42%), Gaps = 12/91 (13%)
Query: 225 FGAGFCATVVAS----PVDVVKTRYMNSPPG--------QYFSPLDCMIKMVAQEGPTAF 272
F G A++VA PVD+ KTR +Y + ++ +EG A
Sbjct: 44 FVYGGLASIVAEFGTFPVDLTKTRLQVQGQSIDARFKEIKYRGMFHALFRICKEEGVLAL 103
Query: 273 YKGFTPSFLRLGSWNVVMFVTYEQLKRALMK 303
Y G P+ LR S+ + Y+ LKR ++
Sbjct: 104 YSGIAPALLRQASYGTIKIGIYQSLKRLFVE 134
>gi|13259543 solute carrier family 25, member 14 isoform UCP5S [Homo
sapiens]
Length = 322
Score = 196 bits (499), Expect = 2e-50
Identities = 108/289 (37%), Positives = 170/289 (58%), Gaps = 16/289 (5%)
Query: 17 FLGAGTAACFADLVTFPLDTAKVRLQIQGENQAVQTARLVQYRGVLGTILTMVRTEGPCS 76
F+ G A+ A+ TFP+D K RLQ+QG++ + ++YRG+ + + + EG +
Sbjct: 41 FVYGGLASIVAEFGTFPVDLTKTRLQVQGQSIDARFKE-IKYRGMFHALFRICKEEGVLA 99
Query: 77 PYNGLVAGLQRQMSFASIRIGLYDSVKQVYTPKGADNSSLTTRILAGCTTGAMAVTCAQP 136
Y+G+ L RQ S+ +I+IG+Y S+K+++ + ++ +L ++ G +G ++ T A P
Sbjct: 100 LYSGIAPALLRQASYGTIKIGIYQSLKRLFVER-LEDETLLINMICGVVSGVISSTIANP 158
Query: 137 TDVVKVRFQASIHLGPSRSDRKYSGTM-DAYRTIAREEGVRGLWKGTLPNIMRNAIVNCA 195
TDV+K+R QA L + G+M ++ I ++EG RGLW+G +P R AIV
Sbjct: 159 TDVLKIRMQAQGSL--------FQGSMIGSFIDIYQQEGTRGLWRGVVPTAQRAAIVVGV 210
Query: 196 EVVTYDILKEKLLDYHLLTDNFPCHFVSAFGAGFCATVVASPVDVVKTRYMNSPP----- 250
E+ YDI K+ L+ ++ D HFVS+F G + ++PVDVV+TR MN
Sbjct: 211 ELPVYDITKKHLILSGMMGDTILTHFVSSFTCGLAGALASNPVDVVRTRMMNQRAIVGHV 270
Query: 251 GQYFSPLDCMIKMVAQEGPTAFYKGFTPSFLRLGSWNVVMFVTYEQLKR 299
Y +D ++KM EG A YKGF P++LRLG WN++ F+TYEQLKR
Sbjct: 271 DLYKGTVDGILKMWKHEGFFALYKGFWPNWLRLGPWNIIFFITYEQLKR 319
Score = 63.2 bits (152), Expect = 3e-10
Identities = 47/197 (23%), Positives = 83/197 (42%), Gaps = 19/197 (9%)
Query: 12 TMAVKFLGAGTAACFADLVTFPLDTAKVRLQIQGENQAVQTARLVQYRGVLGTILTMVRT 71
T+ + + + + + P D K+R+Q QG + ++G+ + + +
Sbjct: 137 TLLINMICGVVSGVISSTIANPTDVLKIRMQAQGS---------LFQGSMIGSFIDIYQQ 187
Query: 72 EGPCSPYNGLVAGLQRQMSFASIRIGLYDSVKQVYTPKGADNSSLTTRILAGCTTGAMAV 131
EG + G+V QR + + +YD K+ G ++ T ++ T G
Sbjct: 188 EGTRGLWRGVVPTAQRAAIVVGVELPVYDITKKHLILSGMMGDTILTHFVSSFTCGLAGA 247
Query: 132 TCAQPTDVVKVRF--QASI--HLGPSRSDRKYSGTMDAYRTIAREEGVRGLWKGTLPNIM 187
+ P DVV+ R Q +I H+ Y GT+D + + EG L+KG PN +
Sbjct: 248 LASNPVDVVRTRMMNQRAIVGHVD------LYKGTVDGILKMWKHEGFFALYKGFWPNWL 301
Query: 188 RNAIVNCAEVVTYDILK 204
R N +TY+ LK
Sbjct: 302 RLGPWNIIFFITYEQLK 318
Score = 37.7 bits (86), Expect = 0.013
Identities = 25/91 (27%), Positives = 39/91 (42%), Gaps = 12/91 (13%)
Query: 225 FGAGFCATVVAS----PVDVVKTRYMNSPPG--------QYFSPLDCMIKMVAQEGPTAF 272
F G A++VA PVD+ KTR +Y + ++ +EG A
Sbjct: 41 FVYGGLASIVAEFGTFPVDLTKTRLQVQGQSIDARFKEIKYRGMFHALFRICKEEGVLAL 100
Query: 273 YKGFTPSFLRLGSWNVVMFVTYEQLKRALMK 303
Y G P+ LR S+ + Y+ LKR ++
Sbjct: 101 YSGIAPALLRQASYGTIKIGIYQSLKRLFVE 131
>gi|58197562 solute carrier family 25, member 30 [Homo sapiens]
Length = 291
Score = 196 bits (498), Expect = 2e-50
Identities = 110/289 (38%), Positives = 166/289 (57%), Gaps = 15/289 (5%)
Query: 17 FLGAGTAACFADLVTFPLDTAKVRLQIQGENQAVQTARLVQYRGVLGTILTMVRTEGPCS 76
F+ G A+ A+ TFP+D K RLQIQG+ + ++YRG+L ++ + R EG +
Sbjct: 9 FVYGGLASITAECGTFPIDLTKTRLQIQGQTNDAKFKE-IRYRGMLHALVRIGREEGLKA 67
Query: 77 PYNGLVAGLQRQMSFASIRIGLYDSVKQVYTPKGADNSSLTTRILAGCTTGAMAVTCAQP 136
Y+G+ + RQ S+ +I+IG Y S+K+++ + D + L ++ G +G ++ T A P
Sbjct: 68 LYSGIAPAMLRQASYGTIKIGTYQSLKRLFIERPEDET-LPINVICGILSGVISSTIANP 126
Query: 137 TDVVKVRFQASIHLGPSRSDRKYSGTMDAYRTIAREEGVRGLWKGTLPNIMRNAIVNCAE 196
TDV+K+R QA +S+ G + + I ++EG RGLWKG R AIV E
Sbjct: 127 TDVLKIRMQA-------QSNTIQGGMIGNFMNIYQQEGTRGLWKGVSLTAQRAAIVVGVE 179
Query: 197 VVTYDILKEKLLDYHLLTDNFPCHFVSAFGAGFCATVVASPVDVVKTRYMNSPP------ 250
+ YDI K+ L+ L+ D HF+S+F G + ++PVDVV+TR MN
Sbjct: 180 LPVYDITKKHLILSGLMGDTVYTHFLSSFTCGLAGALASNPVDVVRTRMMNQRVLRDGRC 239
Query: 251 GQYFSPLDCMIKMVAQEGPTAFYKGFTPSFLRLGSWNVVMFVTYEQLKR 299
Y LDC+++ EG A YKGF P++LRLG WN++ FVTYEQLK+
Sbjct: 240 SGYTGTLDCLLQTWKNEGFFALYKGFWPNWLRLGPWNIIFFVTYEQLKK 288
Score = 39.3 bits (90), Expect = 0.005
Identities = 25/91 (27%), Positives = 39/91 (42%), Gaps = 8/91 (8%)
Query: 221 FVSAFGAGFCATVVASPVDVVKTRYMNSPPG--------QYFSPLDCMIKMVAQEGPTAF 272
FV A A P+D+ KTR +Y L ++++ +EG A
Sbjct: 9 FVYGGLASITAECGTFPIDLTKTRLQIQGQTNDAKFKEIRYRGMLHALVRIGREEGLKAL 68
Query: 273 YKGFTPSFLRLGSWNVVMFVTYEQLKRALMK 303
Y G P+ LR S+ + TY+ LKR ++
Sbjct: 69 YSGIAPAMLRQASYGTIKIGTYQSLKRLFIE 99
>gi|108860679 solute carrier family 25, member 27 [Homo sapiens]
Length = 323
Score = 181 bits (458), Expect = 1e-45
Identities = 108/310 (34%), Positives = 165/310 (53%), Gaps = 17/310 (5%)
Query: 14 AVKFLGAGTAACFADLVTFPLDTAKVRLQIQGENQAVQTA----RLVQYRGVLGTILTMV 69
A KFL +G AA A+L TFPLD K RLQ+QGE + YRG++ T L ++
Sbjct: 20 ASKFLLSGCAATVAELATFPLDLTKTRLQMQGEAALARLGDGARESAPYRGMVRTALGII 79
Query: 70 RTEGPCSPYNGLVAGLQRQMSFASIRIGLYDSVKQVYTPKGADNS-SLTTRILAGCTTGA 128
EG + G+ + R + ++ R+ Y+ +++V K D L ++ G G
Sbjct: 80 EEEGFLKLWQGVTPAIYRHVVYSGGRMVTYEHLREVVFGKSEDEHYPLWKSVIGGMMAGV 139
Query: 129 MAVTCAQPTDVVKVRFQASIHLGPSRSDRKYSGTMDAYRTIAREEGVRGLWKGTLPNIMR 188
+ A PTD+VKV+ Q ++ G A+ I E G+RGLW G +PNI R
Sbjct: 140 IGQFLANPTDLVKVQMQMEGKRKLEGKPLRFRGVHHAFAKILAEGGIRGLWAGWVPNIQR 199
Query: 189 NAIVNCAEVVTYDILKEKLLDYHLLTDNFPCHFVSAFGAGFCATVVASPVDVVKTRYMNS 248
A+VN ++ TYD +K L+ L DN H +S+ +G A+++ +P DV+K+R MN
Sbjct: 200 AALVNMGDLTTYDTVKHYLVLNTPLEDNIMTHGLSSLCSGLVASILGTPADVIKSRIMNQ 259
Query: 249 PPGQ------YFSPLDCMIKMVAQEGPTAFYKGFTPSFLRLGSWNVVMFVTYEQLKRALM 302
P + Y S DC+I+ V EG + YKGF PS+LR+ W++V ++TYE+++
Sbjct: 260 PRDKQGRGLLYKSSTDCLIQAVQGEGFMSLYKGFLPSWLRMTPWSMVFWLTYEKIR---- 315
Query: 303 KVQMLRESPF 312
+M SPF
Sbjct: 316 --EMSGVSPF 323
>gi|21361114 solute carrier family 25 (mitochondrial carrier;
oxoglutarate carrier), member 11 [Homo sapiens]
Length = 314
Score = 163 bits (413), Expect = 2e-40
Identities = 100/304 (32%), Positives = 152/304 (50%), Gaps = 12/304 (3%)
Query: 5 KPSDVPPTMAVKFLGAGTAACFADLVTFPLDTAKVRLQIQGENQAVQTARLVQYRGVLGT 64
KP P + VKFL G A A + PLD K R+Q+ GE A+ +Y+
Sbjct: 15 KPRTSPKS--VKFLFGGLAGMGATVFVQPLDLVKNRMQLSGEG-----AKTREYKTSFHA 67
Query: 65 ILTMVRTEGPCSPYNGLVAGLQRQMSFASIRIGLYDSVKQVYTPKGADNSSLTTRILAGC 124
+ ++++ EG Y GL AGL RQ ++ + R+G+Y + + T + + G
Sbjct: 68 LTSILKAEGLRGIYTGLSAGLLRQATYTTTRLGIYTVLFERLTGADGTPPGFLLKAVIGM 127
Query: 125 TTGAMAVTCAQPTDVVKVRFQASIHLGPSRSDRKYSGTMDAYRTIAREEGVRGLWKGTLP 184
T GA P +V +R A L P+ R Y +A I REEGV LW+G +P
Sbjct: 128 TAGATGAFVGTPAEVALIRMTADGRL-PADQRRGYKNVFNALIRITREEGVLTLWRGCIP 186
Query: 185 NIMRNAIVNCAEVVTYDILKEKLLDYHLLTDNFPCHFVSAFGAGFCATVVASPVDVVKTR 244
+ R +VN A++ +Y K+ LLD +DN CHF ++ +G T + PVD+ KTR
Sbjct: 187 TMARAVVVNAAQLASYSQSKQFLLDSGYFSDNILCHFCASMISGLVTTAASMPVDIAKTR 246
Query: 245 YMN----SPPGQYFSPLDCMIKMVAQEGPTAFYKGFTPSFLRLGSWNVVMFVTYEQLKRA 300
N +Y + LD + K+V EG + +KGFTP + RLG V+ F+ EQ+ +A
Sbjct: 247 IQNMRMIDGKPEYKNGLDVLFKVVRYEGFFSLWKGFTPYYARLGPHTVLTFIFLEQMNKA 306
Query: 301 LMKV 304
++
Sbjct: 307 YKRL 310
>gi|20149598 solute carrier family 25 (mitochondrial carrier;
dicarboxylate transporter), member 10 [Homo sapiens]
Length = 287
Score = 160 bits (405), Expect = 1e-39
Identities = 102/279 (36%), Positives = 145/279 (51%), Gaps = 13/279 (4%)
Query: 21 GTAACFADLVTFPLDTAKVRLQIQGENQAVQTARLVQYRGVLGTILTMVRTEGPCSPYNG 80
G A+C A T PLD KV LQ Q E + T G L +VRT+G + Y+G
Sbjct: 14 GLASCGAACCTHPLDLLKVHLQTQQEVKLRMT----------GMALRVVRTDGILALYSG 63
Query: 81 LVAGLQRQMSFASIRIGLYDSVKQVYTPKGADNSSLTTRILAGCTTGAMAVTCAQPTDVV 140
L A L RQM+++ R +Y++V+ ++L G +G P D+V
Sbjct: 64 LSASLCRQMTYSLTRFAIYETVRDRVAKGSQGPLPFHEKVLLGSVSGLAGGFVGTPADLV 123
Query: 141 KVRFQASIHLGPSRSDRKYSGTMDAYRTIAREEGVRGLWKGTLPNIMRNAIVNCAEVVTY 200
VR Q + L P R Y+ +D +AREEG+R L+ G R A+V ++ Y
Sbjct: 124 NVRMQNDVKL-PQGQRRNYAHALDGLYRVAREEGLRRLFSGATMASSRGALVTVGQLSCY 182
Query: 201 DILKEKLLDYHLLTDNFPCHFVSAFGAGFCATVVASPVDVVKTRYMNSPPGQYFSPLDCM 260
D K+ +L L+DN HFV++F AG CAT + P+DV+KTR MNS G+Y C
Sbjct: 183 DQAKQLVLSTGYLSDNIFTHFVASFIAGGCATFLCQPLDVLKTRLMNS-KGEYQGVFHCA 241
Query: 261 IKMVAQEGPTAFYKGFTPSFLRLGSWNVVMFVTYEQLKR 299
++ A+ GP AFYKG P+ +RL V+ FV EQL++
Sbjct: 242 VE-TAKLGPLAFYKGLVPAGIRLIPHTVLTFVFLEQLRK 279
Score = 47.4 bits (111), Expect = 2e-05
Identities = 46/196 (23%), Positives = 80/196 (40%), Gaps = 28/196 (14%)
Query: 130 AVTCAQPTDVVKVRFQASIHLGPSRSDRKYSGTMDAYRTIAREEGVRGLWKGTLPNIMRN 189
A C P D++KV Q ++ + K T A R + R +G+ L+ G ++ R
Sbjct: 20 AACCTHPLDLLKVHLQ-------TQQEVKLRMTGMALRVV-RTDGILALYSGLSASLCRQ 71
Query: 190 AIVNCAEVVTYDILKEKL-------LDYHLLTDNFPCHFVSAFGAGFCATVVASPVDVVK 242
+ Y+ +++++ L +H + VS GF V +P D+V
Sbjct: 72 MTYSLTRFAIYETVRDRVAKGSQGPLPFH---EKVLLGSVSGLAGGF----VGTPADLVN 124
Query: 243 TRYMNS---PPGQ---YFSPLDCMIKMVAQEGPTAFYKGFTPSFLRLGSWNVVMFVTYEQ 296
R N P GQ Y LD + ++ +EG + G T + R V Y+Q
Sbjct: 125 VRMQNDVKLPQGQRRNYAHALDGLYRVAREEGLRRLFSGATMASSRGALVTVGQLSCYDQ 184
Query: 297 LKRALMKVQMLRESPF 312
K+ ++ L ++ F
Sbjct: 185 AKQLVLSTGYLSDNIF 200
>gi|46409330 solute carrier family 25, member 34 [Homo sapiens]
Length = 304
Score = 122 bits (307), Expect = 3e-28
Identities = 90/308 (29%), Positives = 145/308 (47%), Gaps = 22/308 (7%)
Query: 9 VPPTMAVKFLGAGTAACFADLVTFPLDTAKVRLQIQGENQAVQTARLVQYRGVLGTILTM 68
VPP AV + +A C A + T PL+ K RLQ+QGE QA T Y G + ++ +
Sbjct: 4 VPP--AVDLVLGASACCLACVFTNPLEVVKTRLQLQGELQARGTYPR-PYHGFIASVAAV 60
Query: 69 VRTEGPCSPYNGLVAGLQRQMSFASIRIGLYDSVKQVYTPKGADNSSLTTRILAGCTTGA 128
R +G GL AGL Q +R Y Q + + ++AG GA
Sbjct: 61 ARADGLWGLQKGLAAGLLYQGLMNGVRFYCYSLACQAGLTQQPGGT-----VVAGAVAGA 115
Query: 129 MAVTCAQPTDVVKVRFQA----SIHLGPSRSDRKYSGTMDAYRTIAREEGVRGLWKGTLP 184
+ P ++K + QA ++ +G + + G ++ TI R++G+ GLW+G
Sbjct: 116 LGAFVGSPAYLIKTQLQAQTVAAVAVGHQHNHQTVLGALE---TIWRQQGLLGLWQGVGG 172
Query: 185 NIMRNAIVNCAEVVTYDILKEKLLDYHLLT-DNFPCHFVSAFGAGFCATVVASPVDVVKT 243
+ R + + A++ T+ K + L D++ + VV +P DVV T
Sbjct: 173 AVPRVMVGSAAQLATFASAKAWVQKQQWLPEDSWLVALAGGMISSIAVVVVMTPFDVVST 232
Query: 244 RYMNSPP-----GQYFSPL-DCMIKMVAQEGPTAFYKGFTPSFLRLGSWNVVMFVTYEQL 297
R N P GQ + L DCM+K+ QEGP A YKG P++LRLG ++ + +++L
Sbjct: 233 RLYNQPVDTAGRGQLYGGLTDCMVKIWRQEGPLALYKGLGPAYLRLGPHTILSMLFWDEL 292
Query: 298 KRALMKVQ 305
++ + Q
Sbjct: 293 RKLAGRAQ 300
>gi|46397377 chromosome 14 open reading frame 68 [Homo sapiens]
Length = 308
Score = 100 bits (250), Expect = 1e-21
Identities = 85/298 (28%), Positives = 126/298 (42%), Gaps = 40/298 (13%)
Query: 30 VTFPLDTAKVRLQIQGENQAVQTARLVQYRGVLGTILTMVRTEGPCSPYNGL-----VAG 84
V +PLDT KVR+Q + + Y G+ + E Y GL
Sbjct: 16 VGYPLDTVKVRIQTEPK-----------YTGIWHCVRDTYHRERVWGFYRGLSLPVCTVS 64
Query: 85 LQRQMSFASIRIGLYDSVKQVYTPKGADNSSLTTRILAGCTTGAMAVTCAQPTDVVKVRF 144
L +SF + R L + Y A + L+GC +G + V PT+V KVR
Sbjct: 65 LVSSVSFGTYRHCLAHICRLRYGNPDAKPTKADIT-LSGCASGLVRVFLTSPTEVAKVRL 123
Query: 145 QASIH---------------------LGPSRSDRKYSGTMDAYRTIAREEGVRGLWKGTL 183
Q + P+ + KY G + T+AREEG+ GL+KG+
Sbjct: 124 QTQTQAQKQQRRLSASGPLAVPPMCPVPPACPEPKYRGPLHCLATVAREEGLCGLYKGSS 183
Query: 184 PNIMRNAIVNCAEVVTYDILKEKLLDYHLLTDNFPCHFVSAFGAGFCATVVASPVDVVKT 243
++R+ ++Y +L E L + P V+ AG A VA+P+DV+K+
Sbjct: 184 ALVLRDGHSFATYFLSYAVLCEWLSPAGHSRPDVPGVLVAGGCAGVLAWAVATPMDVIKS 243
Query: 244 RYMNSPPGQ--YFSPLDCMIKMVAQEGPTAFYKGFTPSFLRLGSWNVVMFVTYEQLKR 299
R GQ Y L CM+ V +EGP +KG + R N+V+FV YE + R
Sbjct: 244 RLQADGQGQRRYRGLLHCMVTSVREEGPRVLFKGLVLNCCRAFPVNMVVFVAYEAVLR 301
Score = 74.3 bits (181), Expect = 1e-13
Identities = 67/215 (31%), Positives = 91/215 (42%), Gaps = 28/215 (13%)
Query: 8 DVPPTMAVKFLGAGTAACFADLVTFPLDTAKVRLQIQGENQAVQTARL------------ 55
D PT A L + +T P + AKVRLQ Q + Q Q RL
Sbjct: 90 DAKPTKADITLSGCASGLVRVFLTSPTEVAKVRLQTQTQAQK-QQRRLSASGPLAVPPMC 148
Query: 56 --------VQYRGVLGTILTMVRTEGPCSPYNGLVAGLQRQ-MSFASIRIGLYDSVKQVY 106
+YRG L + T+ R EG C Y G A + R SFA+ + Y + +
Sbjct: 149 PVPPACPEPKYRGPLHCLATVAREEGLCGLYKGSSALVLRDGHSFATYFLS-YAVLCEWL 207
Query: 107 TPKGADNSSLTTRILAGCTTGAMAVTCAQPTDVVKVRFQASIHLGPSRSDRKYSGTMDAY 166
+P G + ++AG G +A A P DV+K R QA + R+Y G +
Sbjct: 208 SPAGHSRPDVPGVLVAGGCAGVLAWAVATPMDVIKSRLQAD-----GQGQRRYRGLLHCM 262
Query: 167 RTIAREEGVRGLWKGTLPNIMRNAIVNCAEVVTYD 201
T REEG R L+KG + N R VN V Y+
Sbjct: 263 VTSVREEGPRVLFKGLVLNCCRAFPVNMVVFVAYE 297
Score = 42.0 bits (97), Expect = 7e-04
Identities = 48/209 (22%), Positives = 70/209 (33%), Gaps = 41/209 (19%)
Query: 121 LAGCTTGAMAVTCAQPTDVVKVRFQASIHLGPSRSDRKYSGTMDAYRTIAREEGVRGLWK 180
+AG G V P D VKVR Q ++ KY+G R E V G ++
Sbjct: 4 VAGAIGGVCGVAVGYPLDTVKVRIQ---------TEPKYTGIWHCVRDTYHRERVWGFYR 54
Query: 181 GTLPNIMRNAIVNCAEVVTY-DILKEKLLDYHLLTDNFPCH---FVSAFGAGFCATVVAS 236
G + ++V+ TY L + D P +S +G + S
Sbjct: 55 GLSLPVCTVSLVSSVSFGTYRHCLAHICRLRYGNPDAKPTKADITLSGCASGLVRVFLTS 114
Query: 237 PVDVVKTRYMNS----------------------------PPGQYFSPLDCMIKMVAQEG 268
P +V K R P +Y PL C+ + +EG
Sbjct: 115 PTEVAKVRLQTQTQAQKQQRRLSASGPLAVPPMCPVPPACPEPKYRGPLHCLATVAREEG 174
Query: 269 PTAFYKGFTPSFLRLGSWNVVMFVTYEQL 297
YKG + LR G F++Y L
Sbjct: 175 LCGLYKGSSALVLRDGHSFATYFLSYAVL 203
Score = 32.3 bits (72), Expect = 0.55
Identities = 21/74 (28%), Positives = 30/74 (40%), Gaps = 2/74 (2%)
Query: 221 FVSAFGAGFCATVVASPVDVVKTRYMNSPPGQYFSPLDCMIKMVAQEGPTAFYKGFTPSF 280
FV+ G C V P+D VK R P +Y C+ +E FY+G +
Sbjct: 3 FVAGAIGGVCGVAVGYPLDTVKVRIQTEP--KYTGIWHCVRDTYHRERVWGFYRGLSLPV 60
Query: 281 LRLGSWNVVMFVTY 294
+ + V F TY
Sbjct: 61 CTVSLVSSVSFGTY 74
>gi|116235462 solute carrier family 25, member 45 isoform a [Homo
sapiens]
Length = 288
Score = 99.4 bits (246), Expect = 4e-21
Identities = 80/293 (27%), Positives = 125/293 (42%), Gaps = 21/293 (7%)
Query: 16 KFLGAGTAACFADLVTFPLDTAKVRLQIQGENQAVQTARLVQYRGVLGTILTMVRTEGPC 75
+F+ + ++ P DT KVRLQ Q YRG++ ++ + R E
Sbjct: 5 EFVAGWISGALGLVLGHPFDTVKVRLQTQ-----------TTYRGIVDCMVKIYRHESLL 53
Query: 76 SPYNGLVAGLQRQMSFASIRIGLYDSVKQVYTP-----KGADNSSLTTRILAGCTTGAMA 130
+ G+ + S+ G+Y + V T + A S LAGCT G +
Sbjct: 54 GFFKGMSFPIASIAVVNSVLFGVYSNTLLVLTATSHQERRAQPPSYMHIFLAGCTGGFLQ 113
Query: 131 VTCAQPTDVVKVRFQASIH--LGPSRSDRKYSGTMDAYRTIAREEGVRGLWKGTLPNIMR 188
C P D++KVR Q P +Y G + +I REEG RGL++G +R
Sbjct: 114 AYCLAPFDLIKVRLQNQTEPRAQPGSPPPRYQGPVHCAASIFREEGPRGLFRGAWALTLR 173
Query: 189 NAIVNCAEVVTYDILKEKLLDYHLLTDNFPCHFVSAFGAGFCATVVASPVDVVKTRYMNS 248
+ +TY+ L + + F AG + V A+P+D++K+R
Sbjct: 174 DTPTVGIYFITYEGLCRQYTPEGQNPSSATVLVAGGF-AGIASWVAATPLDMIKSRMQMD 232
Query: 249 PPGQ--YFSPLDCMIKMVAQEGPTAFYKGFTPSFLRLGSWNVVMFVTYEQLKR 299
+ Y LDCM+ + QEG F++G T + R N V F++YE L R
Sbjct: 233 GLRRRVYQGMLDCMVSSIRQEGLGVFFRGVTINSARAFPVNAVTFLSYEYLLR 285
Score = 72.4 bits (176), Expect = 5e-13
Identities = 58/194 (29%), Positives = 86/194 (44%), Gaps = 6/194 (3%)
Query: 10 PPTMAVKFLGAGTAACFADLVTFPLDTAKVRLQIQGENQAVQTARLVQYRGVLGTILTMV 69
PP+ FL T P D KVRLQ Q E +A + +Y+G + ++
Sbjct: 96 PPSYMHIFLAGCTGGFLQAYCLAPFDLIKVRLQNQTEPRAQPGSPPPRYQGPVHCAASIF 155
Query: 70 RTEGPCSPYNGLVAGLQRQMSFASIRIGLYDSVKQVYTPKGADNSSLTTRILAGCTTGAM 129
R EGP + G A R I Y+ + + YTP+G + SS T ++AG G
Sbjct: 156 REEGPRGLFRGAWALTLRDTPTVGIYFITYEGLCRQYTPEGQNPSSATV-LVAGGFAGIA 214
Query: 130 AVTCAQPTDVVKVRFQASIHLGPSRSDRKYSGTMDAYRTIAREEGVRGLWKGTLPNIMRN 189
+ A P D++K R Q G R R Y G +D + R+EG+ ++G N R
Sbjct: 215 SWVAATPLDMIKSRMQMD---GLRR--RVYQGMLDCMVSSIRQEGLGVFFRGVTINSARA 269
Query: 190 AIVNCAEVVTYDIL 203
VN ++Y+ L
Sbjct: 270 FPVNAVTFLSYEYL 283
Score = 31.6 bits (70), Expect = 0.95
Identities = 19/68 (27%), Positives = 32/68 (47%), Gaps = 7/68 (10%)
Query: 6 PSDVPPTMAVKFLGAGTAACFADLVTFPLDTAKVRLQIQGENQAVQTARLVQYRGVLGTI 65
P P+ A + G A + + PLD K R+Q+ G + V Y+G+L +
Sbjct: 194 PEGQNPSSATVLVAGGFAGIASWVAATPLDMIKSRMQMDGLRRRV-------YQGMLDCM 246
Query: 66 LTMVRTEG 73
++ +R EG
Sbjct: 247 VSSIRQEG 254
>gi|156071462 solute carrier family 25, member A6 [Homo sapiens]
Length = 298
Score = 99.0 bits (245), Expect = 5e-21
Identities = 80/303 (26%), Positives = 134/303 (44%), Gaps = 24/303 (7%)
Query: 12 TMAVKFLGAGTAACFADLVTFPLDTAKVRLQIQGENQAVQTARLVQYRGVLGTILTMVRT 71
+ A FL G AA + P++ K+ LQ+Q ++ + + QY+G++ I+ + +
Sbjct: 7 SFAKDFLAGGIAAAISKTAVAPIERVKLLLQVQHASKQIAADK--QYKGIVDCIVRIPKE 64
Query: 72 EGPCSPYNGLVAGLQRQMSFASIRIGLYDSVKQVYTPKGADNSSLTTRILAGC-----TT 126
+G S + G +A + R ++ D KQ++ G D + R AG
Sbjct: 65 QGVLSFWRGNLANVIRYFPTQALNFAFKDKYKQIFLG-GVDKHTQFWRYFAGNLASGGAA 123
Query: 127 GAMAVTCAQPTDVVKVRFQASIHLGPSRSDRKYSGTMDAYRTIAREEGVRGLWKGTLPNI 186
GA ++ P D + R A + G S ++R++ G D I + +G+RGL++G ++
Sbjct: 124 GATSLCFVYPLDFARTRLAADV--GKSGTEREFRGLGDCLVKITKSDGIRGLYQGFSVSV 181
Query: 187 MRNAIVNCAEVVTYDILKEKLLD---YHLLTDNFPCHFVSAFGAGFCATVVASPVDVVKT 243
I A YD K L D H++ V+A A VV+ P D V+
Sbjct: 182 QGIIIYRAAYFGVYDTAKGMLPDPKNTHIVVSWMIAQTVTA-----VAGVVSYPFDTVRR 236
Query: 244 RYM-----NSPPGQYFSPLDCMIKMVAQEGPTAFYKGFTPSFLRLGSWNVVMFVTYEQLK 298
R M Y +DC K+ EG AF+KG + LR G + V Y++LK
Sbjct: 237 RMMMQSGRKGADIMYTGTVDCWRKIFRDEGGKAFFKGAWSNVLR-GMGGAFVLVLYDELK 295
Query: 299 RAL 301
+ +
Sbjct: 296 KVI 298
Score = 38.5 bits (88), Expect = 0.008
Identities = 26/103 (25%), Positives = 48/103 (46%), Gaps = 5/103 (4%)
Query: 3 GLKPSDVPPTMAVKFLGAGTAACFADLVTFPLDTAKVRLQIQGENQAVQTARLVQYRGVL 62
G+ P + V ++ A T A +V++P DT + R+ +Q + + Y G +
Sbjct: 200 GMLPDPKNTHIVVSWMIAQTVTAVAGVVSYPFDTVRRRMMMQSGRKGAD----IMYTGTV 255
Query: 63 GTILTMVRTEGPCSPYNGLVAGLQRQMSFASIRIGLYDSVKQV 105
+ R EG + + G + + R M A + + LYD +K+V
Sbjct: 256 DCWRKIFRDEGGKAFFKGAWSNVLRGMGGAFVLV-LYDELKKV 297
>gi|4557403 carnitine/acylcarnitine translocase [Homo sapiens]
Length = 301
Score = 96.3 bits (238), Expect = 3e-20
Identities = 82/297 (27%), Positives = 124/297 (41%), Gaps = 18/297 (6%)
Query: 5 KPSDVPPTMAVKFLGAGTAACFADLVTFPLDTAKVRLQIQGENQAVQTARLVQYRGVLGT 64
+P + P L G V PLDT KVRLQ Q + Q Y G
Sbjct: 4 QPKPISPLK--NLLAGGFGGVCLVFVGHPLDTVKVRLQTQPPSLPGQPP---MYSGTFDC 58
Query: 65 ILTMVRTEGPCSPYNGLVA---GLQRQMSFASIRIGLYDSVKQVYTPKGADNSSLTTRIL 121
+ EG Y G+ A G+ + GL ++Q + D S
Sbjct: 59 FRKTLFREGITGLYRGMAAPIIGVTPMFAVCFFGFGLGKKLQQKHPE---DVLSYPQLFA 115
Query: 122 AGCTTGAMAVTCAQPTDVVKVRFQASIHLGPSRSDRKYSGTMDAYRTIAREEGVRGLWKG 181
AG +G P + +K Q G S KY+GT+D + + +E G+RG++KG
Sbjct: 116 AGMLSGVFTTGIMTPGERIKCLLQIQASSGES----KYTGTLDCAKKLYQEFGIRGIYKG 171
Query: 182 TLPNIMRNAIVNCAEVVTYDILKEKLLDYHLLTDNF--PCHFVSAFGAGFCATVVASPVD 239
T+ +MR+ + +TY+ LK P V+ AG VA P D
Sbjct: 172 TVLTLMRDVPASGMYFMTYEWLKNIFTPEGKRVSELSAPRILVAGGIAGIFNWAVAIPPD 231
Query: 240 VVKTRYMNSPPGQYFSPL-DCMIKMVAQEGPTAFYKGFTPSFLRLGSWNVVMFVTYE 295
V+K+R+ +PPG+Y + D + +++ EG T+ YKGF +R N F+ +E
Sbjct: 232 VLKSRFQTAPPGKYPNGFRDVLRELIRDEGVTSLYKGFNAVMIRAFPANAACFLGFE 288
Score = 58.9 bits (141), Expect = 6e-09
Identities = 49/182 (26%), Positives = 78/182 (42%), Gaps = 4/182 (2%)
Query: 120 ILAGCTTGAMAVTCAQPTDVVKVRFQASIHLGPSRSDRKYSGTMDAYRTIAREEGVRGLW 179
+LAG G V P D VKVR Q P + YSGT D +R EG+ GL+
Sbjct: 14 LLAGGFGGVCLVFVGHPLDTVKVRLQTQPPSLPGQPPM-YSGTFDCFRKTLFREGITGLY 72
Query: 180 KGTLPNIMRNAIVNCAEVVTYDILKEKLLDYHLLTDNFPCHFVSAFGAGFCATVVASPVD 239
+G I+ + + + K+ + ++P F + +G T + +P +
Sbjct: 73 RGMAAPIIGVTPMFAVCFFGFGLGKKLQQKHPEDVLSYPQLFAAGMLSGVFTTGIMTPGE 132
Query: 240 VVKTRYM---NSPPGQYFSPLDCMIKMVAQEGPTAFYKGFTPSFLRLGSWNVVMFVTYEQ 296
+K +S +Y LDC K+ + G YKG + +R + + F+TYE
Sbjct: 133 RIKCLLQIQASSGESKYTGTLDCAKKLYQEFGIRGIYKGTVLTLMRDVPASGMYFMTYEW 192
Query: 297 LK 298
LK
Sbjct: 193 LK 194
Score = 55.1 bits (131), Expect = 8e-08
Identities = 53/189 (28%), Positives = 81/189 (42%), Gaps = 16/189 (8%)
Query: 17 FLGAGTAACFADLVTFPLDTAKVRLQIQGENQAVQTARLVQYRGVLGTILTMVRTEGPCS 76
F + F + P + K LQIQ + + Y G L + + G
Sbjct: 114 FAAGMLSGVFTTGIMTPGERIKCLLQIQASSGESK------YTGTLDCAKKLYQEFGIRG 167
Query: 77 PYNGLVAGLQRQMSFASIRIGLYDSVKQVYTPKGADNSSLTT-RIL-AGCTTGAMAVTCA 134
Y G V L R + + + Y+ +K ++TP+G S L+ RIL AG G A
Sbjct: 168 IYKGTVLTLMRDVPASGMYFMTYEWLKNIFTPEGKRVSELSAPRILVAGGIAGIFNWAVA 227
Query: 135 QPTDVVKVRFQASIHLGPSRSDRKY-SGTMDAYRTIAREEGVRGLWKGTLPNIMRNAIVN 193
P DV+K RFQ + KY +G D R + R+EGV L+KG ++R N
Sbjct: 228 IPPDVLKSRFQTA-------PPGKYPNGFRDVLRELIRDEGVTSLYKGFNAVMIRAFPAN 280
Query: 194 CAEVVTYDI 202
A + +++
Sbjct: 281 AACFLGFEV 289
Score = 38.9 bits (89), Expect = 0.006
Identities = 23/82 (28%), Positives = 31/82 (37%), Gaps = 6/82 (7%)
Query: 228 GFCATVVASPVDVVKTRYMNSPPG------QYFSPLDCMIKMVAQEGPTAFYKGFTPSFL 281
G C V P+D VK R PP Y DC K + +EG T Y+G +
Sbjct: 21 GVCLVFVGHPLDTVKVRLQTQPPSLPGQPPMYSGTFDCFRKTLFREGITGLYRGMAAPII 80
Query: 282 RLGSWNVVMFVTYEQLKRALMK 303
+ V F + K+ K
Sbjct: 81 GVTPMFAVCFFGFGLGKKLQQK 102
>gi|21389315 solute carrier family 25 (mitochondrial carrier;
citrate transporter), member 1 precursor [Homo sapiens]
Length = 311
Score = 94.7 bits (234), Expect = 9e-20
Identities = 76/292 (26%), Positives = 133/292 (45%), Gaps = 19/292 (6%)
Query: 18 LGAGTAACFADLVTFPLDTAKVRLQIQGENQAVQTARLVQYRGVLGTILTMVRTEGPCSP 77
L G A +TFP + K +LQ+ + + +YRG+ + VR+ G
Sbjct: 30 LAGGLAGGIEICITFPTEYVKTQLQLD------ERSHPPRYRGIGDCVRQTVRSHGVLGL 83
Query: 78 YNGLVAGLQRQMSFASIRIGLYDSVKQVYTPKGADNSSLTTRILAGCTTG-AMAVTCAQP 136
Y GL + L + A++R G+++ + + T +L G G A AV P
Sbjct: 84 YRGLSSLLYGSIPKAAVRFGMFEFLSN-HMRDAQGRLDSTRGLLCGLGAGVAEAVVVVCP 142
Query: 137 TDVVKVRFQASIHLGPSRSDRKYSGTMDAYRTIAREEGVRGLWKGTLPNIMRNAIVNCAE 196
+ +KV+F IH + + KY G R I RE+G++G ++G +++ +
Sbjct: 143 METIKVKF---IH-DQTSPNPKYRGFFHGVREIVREQGLKGTYQGLTATVLKQG---SNQ 195
Query: 197 VVTYDILKEKLLDYHLLTDNFPCH--FVSAFGA--GFCATVVASPVDVVKTRYMNSPPGQ 252
+ + ++ Y N P + FGA G + +P+DV+KTR +
Sbjct: 196 AIRFFVMTSLRNWYRGDNPNKPMNPLITGVFGAIAGAASVFGNTPLDVIKTRMQGLEAHK 255
Query: 253 YFSPLDCMIKMVAQEGPTAFYKGFTPSFLRLGSWNVVMFVTYEQLKRALMKV 304
Y + DC ++++ +EG AFYKG P R+ ++FV Y+++ + L KV
Sbjct: 256 YRNTWDCGLQILKKEGLKAFYKGTVPRLGRVCLDVAIVFVIYDEVVKLLNKV 307
Score = 57.0 bits (136), Expect = 2e-08
Identities = 49/184 (26%), Positives = 82/184 (44%), Gaps = 11/184 (5%)
Query: 120 ILAGCTTGAMAVTCAQPTDVVKVRFQASIHLGPSRSDRKYSGTMDAYRTIAREEGVRGLW 179
ILAG G + + PT+ VK + Q P R Y G D R R GV GL+
Sbjct: 29 ILAGGLAGGIEICITFPTEYVKTQLQLDERSHPPR----YRGIGDCVRQTVRSHGVLGLY 84
Query: 180 KGTLPNIMRNAIVNCA-EVVTYDILKEKLLDYHLLTDNFPCHFVSAFGAGFC-ATVVASP 237
+G L +++ +I A ++ L + D D+ + GAG A VV P
Sbjct: 85 RG-LSSLLYGSIPKAAVRFGMFEFLSNHMRDAQGRLDS-TRGLLCGLGAGVAEAVVVVCP 142
Query: 238 VDVVKTRYMN---SPPGQYFSPLDCMIKMVAQEGPTAFYKGFTPSFLRLGSWNVVMFVTY 294
++ +K ++++ SP +Y + ++V ++G Y+G T + L+ GS + F
Sbjct: 143 METIKVKFIHDQTSPNPKYRGFFHGVREIVREQGLKGTYQGLTATVLKQGSNQAIRFFVM 202
Query: 295 EQLK 298
L+
Sbjct: 203 TSLR 206
>gi|156071459 solute carrier family 25, member 5 [Homo sapiens]
Length = 298
Score = 94.4 bits (233), Expect = 1e-19
Identities = 75/307 (24%), Positives = 133/307 (43%), Gaps = 26/307 (8%)
Query: 7 SDVPPTMAVKFLGAGTAACFADLVTFPLDTAKVRLQIQGENQAVQTARLVQYRGVLGTIL 66
+D + A FL G AA + P++ K+ LQ+Q ++ + + QY+G++ ++
Sbjct: 2 TDAAVSFAKDFLAGGVAAAISKTAVAPIERVKLLLQVQHASKQITADK--QYKGIIDCVV 59
Query: 67 TMVRTEGPCSPYNGLVAGLQRQMSFASIRIGLYDSVKQVYTPKGADNSS-----LTTRIL 121
+ + +G S + G +A + R ++ D KQ++ G D + +
Sbjct: 60 RIPKEQGVLSFWRGNLANVIRYFPTQALNFAFKDKYKQIFL-GGVDKRTQFWLYFAGNLA 118
Query: 122 AGCTTGAMAVTCAQPTDVVKVRFQASIHLGPSRSDRKYSGTMDAYRTIAREEGVRGLWKG 181
+G GA ++ P D + R A + G + ++R++ G D I + +G++GL++G
Sbjct: 119 SGGAAGATSLCFVYPLDFARTRLAADV--GKAGAEREFRGLGDCLVKIYKSDGIKGLYQG 176
Query: 182 TLPNIMRNAIVNCAEVVTYDILKEKLLDYHLLTDNFPCHFVSAFGAGFCATVVAS----P 237
++ I A YD K +L D H V ++ T VA P
Sbjct: 177 FNVSVQGIIIYRAAYFGIYDTAK------GMLPDPKNTHIVISWMIAQTVTAVAGLTSYP 230
Query: 238 VDVVKTRYM-----NSPPGQYFSPLDCMIKMVAQEGPTAFYKGFTPSFLRLGSWNVVMFV 292
D V+ R M Y LDC K+ EG AF+KG + LR G + V
Sbjct: 231 FDTVRRRMMMQSGRKGTDIMYTGTLDCWRKIARDEGGKAFFKGAWSNVLR-GMGGAFVLV 289
Query: 293 TYEQLKR 299
Y+++K+
Sbjct: 290 LYDEIKK 296
Score = 58.9 bits (141), Expect = 6e-09
Identities = 49/196 (25%), Positives = 77/196 (39%), Gaps = 9/196 (4%)
Query: 115 SLTTRILAGCTTGAMAVTCAQPTDVVKVRFQASIHLGPSRSDRKYSGTMDAYRTIAREEG 174
S LAG A++ T P + VK+ Q +D++Y G +D I +E+G
Sbjct: 7 SFAKDFLAGGVAAAISKTAVAPIERVKLLLQVQHASKQITADKQYKGIIDCVVRIPKEQG 66
Query: 175 VRGLWKGTLPNIMRNAIVNCAEVVTYDILKEKLLDYHLLTDNFPCHF----VSAFGAGFC 230
V W+G L N++R D K+ L F +F S AG
Sbjct: 67 VLSFWRGNLANVIRYFPTQALNFAFKDKYKQIFLGGVDKRTQFWLYFAGNLASGGAAGAT 126
Query: 231 ATVVASPVDVVKTRYM----NSPPGQYFSPL-DCMIKMVAQEGPTAFYKGFTPSFLRLGS 285
+ P+D +TR + + F L DC++K+ +G Y+GF S +
Sbjct: 127 SLCFVYPLDFARTRLAADVGKAGAEREFRGLGDCLVKIYKSDGIKGLYQGFNVSVQGIII 186
Query: 286 WNVVMFVTYEQLKRAL 301
+ F Y+ K L
Sbjct: 187 YRAAYFGIYDTAKGML 202
Score = 38.5 bits (88), Expect = 0.008
Identities = 25/102 (24%), Positives = 46/102 (45%), Gaps = 5/102 (4%)
Query: 3 GLKPSDVPPTMAVKFLGAGTAACFADLVTFPLDTAKVRLQIQGENQAVQTARLVQYRGVL 62
G+ P + + ++ A T A L ++P DT + R+ +Q + + Y G L
Sbjct: 200 GMLPDPKNTHIVISWMIAQTVTAVAGLTSYPFDTVRRRMMMQSGRKGTD----IMYTGTL 255
Query: 63 GTILTMVRTEGPCSPYNGLVAGLQRQMSFASIRIGLYDSVKQ 104
+ R EG + + G + + R M A + + LYD +K+
Sbjct: 256 DCWRKIARDEGGKAFFKGAWSNVLRGMGGAFVLV-LYDEIKK 296
>gi|41462412 solute carrier family 25, member 35 [Homo sapiens]
Length = 295
Score = 93.2 bits (230), Expect = 3e-19
Identities = 69/241 (28%), Positives = 111/241 (46%), Gaps = 14/241 (5%)
Query: 17 FLGAGTAACFADLVTFPLDTAKVRLQIQGENQAVQTARLVQYRGVLGTILTMVRTEGPCS 76
FL +G AAC A + T PL+ K R+Q+QGE QA T + YR V +T+ + +G +
Sbjct: 3 FLMSGLAACGACVFTNPLEVVKTRMQLQGELQAPGTYQR-HYRNVFHAFITIGKVDGLAA 61
Query: 77 PYNGLVAGLQRQMSFASIRIGLY---DSVKQVYTPKGADNSSLTTRILAGCTTGAMAVTC 133
GL L Q IR+G Y ++ ++T +G + + + AG G M
Sbjct: 62 LQKGLAPALLYQFLMNGIRLGTYGLAEAGGYLHTAEGTHSPARSA--AAGAMAGVMGAYL 119
Query: 134 AQPTDVVKVRFQA----SIHLGPSRSDRKYSGTMDAYRTIAREEGVRGLWKGTLPNIMRN 189
P +VK QA I +G K+ G A I ++ G+ GLW+G L + R
Sbjct: 120 GSPIYMVKTHLQAQAASEIAVG---HQYKHQGMFQALTEIGQKHGLVGLWRGALGGLPRV 176
Query: 190 AIVNCAEVVTYDILKEKLLDYHLL-TDNFPCHFVSAFGAGFCATVVASPVDVVKTRYMNS 248
+ + ++ T+ K+ L + + ++ V+A +G + +P DV TR N
Sbjct: 177 IVGSSTQLCTFSSTKDLLSQWEIFPPQSWKLALVAAMMSGIAVVLAMAPFDVACTRLYNQ 236
Query: 249 P 249
P
Sbjct: 237 P 237
>gi|55749577 solute carrier family 25 (mitochondrial carrier;
adenine nucleotide translocator), member 4 [Homo
sapiens]
Length = 298
Score = 91.3 bits (225), Expect = 1e-18
Identities = 75/296 (25%), Positives = 127/296 (42%), Gaps = 24/296 (8%)
Query: 17 FLGAGTAACFADLVTFPLDTAKVRLQIQGENQAVQTARLVQYRGVLGTILTMVRTEGPCS 76
FL G AA + P++ K+ LQ+Q ++ + + QY+G++ ++ + + +G S
Sbjct: 12 FLAGGVAAAVSKTAVAPIERVKLLLQVQHASKQISAEK--QYKGIIDCVVRIPKEQGFLS 69
Query: 77 PYNGLVAGLQRQMSFASIRIGLYDSVKQVYTPKGADNSSLTTRILA-----GCTTGAMAV 131
+ G +A + R ++ D KQ++ G D R A G GA ++
Sbjct: 70 FWRGNLANVIRYFPTQALNFAFKDKYKQLFL-GGVDRHKQFWRYFAGNLASGGAAGATSL 128
Query: 132 TCAQPTDVVKVRFQASIHLGPSRSDRKYSGTMDAYRTIAREEGVRGLWKGTLPNIMRNAI 191
P D + R A + G + R++ G D I + +G+RGL++G ++ I
Sbjct: 129 CFVYPLDFARTRLAADV--GKGAAQREFHGLGDCIIKIFKSDGLRGLYQGFNVSVQGIII 186
Query: 192 VNCAEVVTYDILKEKLLD---YHLLTDNFPCHFVSAFGAGFCATVVASPVDVVKTRYM-- 246
A YD K L D H+ V+A A +V+ P D V+ R M
Sbjct: 187 YRAAYFGVYDTAKGMLPDPKNVHIFVSWMIAQSVTA-----VAGLVSYPFDTVRRRMMMQ 241
Query: 247 ---NSPPGQYFSPLDCMIKMVAQEGPTAFYKGFTPSFLRLGSWNVVMFVTYEQLKR 299
Y +DC K+ EG AF+KG + LR G + V Y+++K+
Sbjct: 242 SGRKGADIMYTGTVDCWRKIAKDEGAKAFFKGAWSNVLR-GMGGAFVLVLYDEIKK 296
Score = 57.8 bits (138), Expect = 1e-08
Identities = 46/190 (24%), Positives = 75/190 (39%), Gaps = 9/190 (4%)
Query: 121 LAGCTTGAMAVTCAQPTDVVKVRFQASIHLGPSRSDRKYSGTMDAYRTIAREEGVRGLWK 180
LAG A++ T P + VK+ Q ++++Y G +D I +E+G W+
Sbjct: 13 LAGGVAAAVSKTAVAPIERVKLLLQVQHASKQISAEKQYKGIIDCVVRIPKEQGFLSFWR 72
Query: 181 GTLPNIMRNAIVNCAEVVTYDILKEKLL---DYH-LLTDNFPCHFVSAFGAGFCATVVAS 236
G L N++R D K+ L D H F + S AG +
Sbjct: 73 GNLANVIRYFPTQALNFAFKDKYKQLFLGGVDRHKQFWRYFAGNLASGGAAGATSLCFVY 132
Query: 237 PVDVVKTRY-----MNSPPGQYFSPLDCMIKMVAQEGPTAFYKGFTPSFLRLGSWNVVMF 291
P+D +TR + ++ DC+IK+ +G Y+GF S + + F
Sbjct: 133 PLDFARTRLAADVGKGAAQREFHGLGDCIIKIFKSDGLRGLYQGFNVSVQGIIIYRAAYF 192
Query: 292 VTYEQLKRAL 301
Y+ K L
Sbjct: 193 GVYDTAKGML 202
Score = 35.8 bits (81), Expect = 0.050
Identities = 24/102 (23%), Positives = 47/102 (46%), Gaps = 5/102 (4%)
Query: 3 GLKPSDVPPTMAVKFLGAGTAACFADLVTFPLDTAKVRLQIQGENQAVQTARLVQYRGVL 62
G+ P + V ++ A + A LV++P DT + R+ +Q + + Y G +
Sbjct: 200 GMLPDPKNVHIFVSWMIAQSVTAVAGLVSYPFDTVRRRMMMQSGRKGAD----IMYTGTV 255
Query: 63 GTILTMVRTEGPCSPYNGLVAGLQRQMSFASIRIGLYDSVKQ 104
+ + EG + + G + + R M A + + LYD +K+
Sbjct: 256 DCWRKIAKDEGAKAFFKGAWSNVLRGMGGAFVLV-LYDEIKK 296
>gi|13775208 solute carrier family 25 (mitochondrial carrier;
adenine nucleotide translocator), member 31 [Homo
sapiens]
Length = 315
Score = 91.3 bits (225), Expect = 1e-18
Identities = 71/289 (24%), Positives = 131/289 (45%), Gaps = 16/289 (5%)
Query: 18 LGAGTAACFADLVTFPLDTAKVRLQIQGENQAVQTARLVQYRGVLGTILTMVRTEGPCSP 77
L G AA + P++ K+ LQ+Q ++ + +Y+G++ ++ + R +G S
Sbjct: 25 LAGGVAAAVSKTAVAPIERVKLLLQVQASSKQISPE--ARYKGMVDCLVRIPREQGFFSF 82
Query: 78 YNGLVAGLQRQMSFASIRIGLYDSVKQVYTPKGADNSSLTTR-----ILAGCTTGAMAVT 132
+ G +A + R ++ D KQ++ G + R + +G GA ++
Sbjct: 83 WRGNLANVIRYFPTQALNFAFKDKYKQLFM-SGVNKEKQFWRWFLANLASGGAAGATSLC 141
Query: 133 CAQPTDVVKVRFQASIHLGPSRSDRKYSGTMDAYRTIAREEGVRGLWKGTLPNIMRNAIV 192
P D + R I GP +R++ G D IA+ +G+ GL++G ++ +
Sbjct: 142 VVYPLDFARTRLGVDIGKGPE--ERQFKGLGDCIMKIAKSDGIAGLYQGFGVSVQGIIVY 199
Query: 193 NCAEVVTYDILKEKLLDYHLLTDNFPCHFVSAFGAGFCATVVASPVDVVKTRYM---NSP 249
+ YD +K LL T F F A C+ +++ P D V+ R M
Sbjct: 200 RASYFGAYDTVKG-LLPKPKKTP-FLVSFFIAQVVTTCSGILSYPFDTVRRRMMMQSGEA 257
Query: 250 PGQYFSPLDCMIKMVAQEGPTAFYKGFTPSFLRLGSWNVVMFVTYEQLK 298
QY LDC +K+ EG ++F++G + LR G+ ++ V Y+++K
Sbjct: 258 KRQYKGTLDCFVKIYQHEGISSFFRGAFSNVLR-GTGGALVLVLYDKIK 305
Score = 63.2 bits (152), Expect = 3e-10
Identities = 53/210 (25%), Positives = 84/210 (40%), Gaps = 12/210 (5%)
Query: 112 DNSSLTTRILAGCTTGAMAVTCAQPTDVVKVRFQASIHLGPSRSDRKYSGTMDAYRTIAR 171
D SS +LAG A++ T P + VK+ Q + +Y G +D I R
Sbjct: 16 DASSFGKDLLAGGVAAAVSKTAVAPIERVKLLLQVQASSKQISPEARYKGMVDCLVRIPR 75
Query: 172 EEGVRGLWKGTLPNIMRNAIVNCAEVVTYDILKEKLLD----YHLLTDNFPCHFVSAFGA 227
E+G W+G L N++R D K+ + F + S A
Sbjct: 76 EQGFFSFWRGNLANVIRYFPTQALNFAFKDKYKQLFMSGVNKEKQFWRWFLANLASGGAA 135
Query: 228 GFCATVVASPVDVVKTR----YMNSPPGQYFSPL-DCMIKMVAQEGPTAFYKGFTPSFLR 282
G + V P+D +TR P + F L DC++K+ +G Y+GF S
Sbjct: 136 GATSLCVVYPLDFARTRLGVDIGKGPEERQFKGLGDCIMKIAKSDGIAGLYQGFGVSVQG 195
Query: 283 LGSWNVVMFVTYEQLKRALMKVQMLRESPF 312
+ + F Y+ +K L K +++PF
Sbjct: 196 IIVYRASYFGAYDTVKGLLPKP---KKTPF 222
Score = 61.2 bits (147), Expect = 1e-09
Identities = 47/186 (25%), Positives = 85/186 (45%), Gaps = 13/186 (6%)
Query: 21 GTAACFADLVTFPLDTAKVRLQIQ-GENQAVQTARLVQYRGVLGTILTMVRTEGPCSPYN 79
G A + V +PLD A+ RL + G+ + Q++G+ I+ + +++G Y
Sbjct: 133 GAAGATSLCVVYPLDFARTRLGVDIGKGPEER-----QFKGLGDCIMKIAKSDGIAGLYQ 187
Query: 80 GLVAGLQRQMSFASIRIGLYDSVKQVYTPKGADNSSLTTRILAGCTTGAMAVTCAQPTDV 139
G +Q + + + G YD+VK + PK L + +A T + + P D
Sbjct: 188 GFGVSVQGIIVYRASYFGAYDTVKGLL-PKPKKTPFLVSFFIAQVVTTCSGIL-SYPFDT 245
Query: 140 VKVRFQASIHLGPSRSDRKYSGTMDAYRTIAREEGVRGLWKGTLPNIMRNAIVNCAEVVT 199
V+ R + + R+Y GT+D + I + EG+ ++G N++R +V
Sbjct: 246 VRRRMM----MQSGEAKRQYKGTLDCFVKIYQHEGISSFFRGAFSNVLRGT-GGALVLVL 300
Query: 200 YDILKE 205
YD +KE
Sbjct: 301 YDKIKE 306
Score = 37.7 bits (86), Expect = 0.013
Identities = 27/105 (25%), Positives = 48/105 (45%), Gaps = 9/105 (8%)
Query: 3 GLKPSDVPPTMAVKFLGAGTAACFADLVTFPLDTAKVRLQIQ-GENQAVQTARLVQYRGV 61
GL P V F A + ++++P DT + R+ +Q GE + QY+G
Sbjct: 212 GLLPKPKKTPFLVSFFIAQVVTTCSGILSYPFDTVRRRMMMQSGEAKR-------QYKGT 264
Query: 62 LGTILTMVRTEGPCSPYNGLVAGLQRQMSFASIRIGLYDSVKQVY 106
L + + + EG S + G + + R A + + LYD +K+ +
Sbjct: 265 LDCFVKIYQHEGISSFFRGAFSNVLRGTGGALVLV-LYDKIKEFF 308
>gi|186928856 solute carrier family 25, member 19 [Homo sapiens]
Length = 320
Score = 89.0 bits (219), Expect = 5e-18
Identities = 63/196 (32%), Positives = 94/196 (47%), Gaps = 8/196 (4%)
Query: 108 PKGADNSSLTTRILAGCTTGAMAVTCAQPTDVVKVRFQASIHLGPSRSD--RKYSGTMDA 165
P G +N+ + AG +G + P DV+K+RFQ H SRSD KY G + A
Sbjct: 8 PDGRNNTKFQVAV-AGSVSGLVTRALISPFDVIKIRFQLQ-HERLSRSDPSAKYHGILQA 65
Query: 166 YRTIAREEGVRGLWKGTLPNIMRNAIVNCAEVVTYDILKEKLLDYHLLTD--NFPCHFVS 223
R I +EEG WKG +P + + + +++++L E L+ + D F HFV
Sbjct: 66 SRQILQEEGPTAFWKGHVPAQILSIGYGAVQFLSFEMLTE-LVHRGSVYDAREFSVHFVC 124
Query: 224 AFGAGFCATVVASPVDVVKTRYM-NSPPGQYFSPLDCMIKMVAQEGPTAFYKGFTPSFLR 282
A AT+ PVDV++TR+ P Y + + M EGP FYKG P+ +
Sbjct: 125 GGLAACMATLTVHPVDVLRTRFAAQGEPKVYNTLRHAVGTMYRSEGPQVFYKGLAPTLIA 184
Query: 283 LGSWNVVMFVTYEQLK 298
+ + + F Y LK
Sbjct: 185 IFPYAGLQFSCYSSLK 200
Score = 82.0 bits (201), Expect = 6e-16
Identities = 56/185 (30%), Positives = 86/185 (46%), Gaps = 16/185 (8%)
Query: 14 AVKFLGAGTAACFADLVTFPLDTAKVRLQIQGENQAVQTARLVQYRGVLGTILTMVRTEG 73
+V F+ G AAC A L P+D + R QGE + T R + TM R+EG
Sbjct: 119 SVHFVCGGLAACMATLTVHPVDVLRTRFAAQGEPKVYNTLR--------HAVGTMYRSEG 170
Query: 74 PCSPYNGLVAGLQRQMSFASIRIGLYDSVKQVY----TPKGADNSSLTTRILAGCTTGAM 129
P Y GL L +A ++ Y S+K +Y +G N +L +L G G +
Sbjct: 171 PQVFYKGLAPTLIAIFPYAGLQFSCYSSLKHLYKWAIPAEGKKNENL-QNLLCGSGAGVI 229
Query: 130 AVTCAQPTDVVKVRFQAS--IHLGPSRSD-RKYSGTMDAYRTIAREEGVRGLWKGTLPNI 186
+ T P D+ K R Q H + R+Y G MD + + ++EG G +KG P++
Sbjct: 230 SKTLTYPLDLFKKRLQVGGFEHARAAFGQVRRYKGLMDCAKQVLQKEGALGFFKGLSPSL 289
Query: 187 MRNAI 191
++ A+
Sbjct: 290 LKAAL 294
Score = 72.4 bits (176), Expect = 5e-13
Identities = 65/283 (22%), Positives = 116/283 (40%), Gaps = 33/283 (11%)
Query: 33 PLDTAKVRLQIQGENQAVQTARLVQYRGVLGTILTMVRTEGPCSPYNGLVAGLQRQMSFA 92
P D K+R Q+Q E + ++ +Y G+L +++ EGP + + G V + +
Sbjct: 35 PFDVIKIRFQLQHERLS-RSDPSAKYHGILQASRQILQEEGPTAFWKGHVPAQILSIGYG 93
Query: 93 SIRIGLYDSVKQ-VYTPKGADNSSLTTRILAGCTTGAMAVTCAQPTDVVKVRFQASIHLG 151
+++ ++ + + V+ D + + G MA P DV++ RF A
Sbjct: 94 AVQFLSFEMLTELVHRGSVYDAREFSVHFVCGGLAACMATLTVHPVDVLRTRFAAQ---- 149
Query: 152 PSRSDRKYSGTMDAYRTIAREEGVRGLWKGTLPNIMRNAIVNCAEVVTYDILKEKLLDYH 211
+ Y+ A T+ R EG + +KG P ++ + Y LK H
Sbjct: 150 --GEPKVYNTLRHAVGTMYRSEGPQVFYKGLAPTLIAIFPYAGLQFSCYSSLK------H 201
Query: 212 LLTDNFPC---------HFVSAFGAGFCATVVASPVDVVKTR-------YMNSPPGQ--- 252
L P + + GAG + + P+D+ K R + + GQ
Sbjct: 202 LYKWAIPAEGKKNENLQNLLCGSGAGVISKTLTYPLDLFKKRLQVGGFEHARAAFGQVRR 261
Query: 253 YFSPLDCMIKMVAQEGPTAFYKGFTPSFLRLGSWNVVMFVTYE 295
Y +DC +++ +EG F+KG +PS L+ MF +YE
Sbjct: 262 YKGLMDCAKQVLQKEGALGFFKGLSPSLLKAALSTGFMFFSYE 304
>gi|186928860 solute carrier family 25, member 19 [Homo sapiens]
Length = 320
Score = 89.0 bits (219), Expect = 5e-18
Identities = 63/196 (32%), Positives = 94/196 (47%), Gaps = 8/196 (4%)
Query: 108 PKGADNSSLTTRILAGCTTGAMAVTCAQPTDVVKVRFQASIHLGPSRSD--RKYSGTMDA 165
P G +N+ + AG +G + P DV+K+RFQ H SRSD KY G + A
Sbjct: 8 PDGRNNTKFQVAV-AGSVSGLVTRALISPFDVIKIRFQLQ-HERLSRSDPSAKYHGILQA 65
Query: 166 YRTIAREEGVRGLWKGTLPNIMRNAIVNCAEVVTYDILKEKLLDYHLLTD--NFPCHFVS 223
R I +EEG WKG +P + + + +++++L E L+ + D F HFV
Sbjct: 66 SRQILQEEGPTAFWKGHVPAQILSIGYGAVQFLSFEMLTE-LVHRGSVYDAREFSVHFVC 124
Query: 224 AFGAGFCATVVASPVDVVKTRYM-NSPPGQYFSPLDCMIKMVAQEGPTAFYKGFTPSFLR 282
A AT+ PVDV++TR+ P Y + + M EGP FYKG P+ +
Sbjct: 125 GGLAACMATLTVHPVDVLRTRFAAQGEPKVYNTLRHAVGTMYRSEGPQVFYKGLAPTLIA 184
Query: 283 LGSWNVVMFVTYEQLK 298
+ + + F Y LK
Sbjct: 185 IFPYAGLQFSCYSSLK 200
Score = 82.0 bits (201), Expect = 6e-16
Identities = 56/185 (30%), Positives = 86/185 (46%), Gaps = 16/185 (8%)
Query: 14 AVKFLGAGTAACFADLVTFPLDTAKVRLQIQGENQAVQTARLVQYRGVLGTILTMVRTEG 73
+V F+ G AAC A L P+D + R QGE + T R + TM R+EG
Sbjct: 119 SVHFVCGGLAACMATLTVHPVDVLRTRFAAQGEPKVYNTLR--------HAVGTMYRSEG 170
Query: 74 PCSPYNGLVAGLQRQMSFASIRIGLYDSVKQVY----TPKGADNSSLTTRILAGCTTGAM 129
P Y GL L +A ++ Y S+K +Y +G N +L +L G G +
Sbjct: 171 PQVFYKGLAPTLIAIFPYAGLQFSCYSSLKHLYKWAIPAEGKKNENL-QNLLCGSGAGVI 229
Query: 130 AVTCAQPTDVVKVRFQAS--IHLGPSRSD-RKYSGTMDAYRTIAREEGVRGLWKGTLPNI 186
+ T P D+ K R Q H + R+Y G MD + + ++EG G +KG P++
Sbjct: 230 SKTLTYPLDLFKKRLQVGGFEHARAAFGQVRRYKGLMDCAKQVLQKEGALGFFKGLSPSL 289
Query: 187 MRNAI 191
++ A+
Sbjct: 290 LKAAL 294
Score = 72.4 bits (176), Expect = 5e-13
Identities = 65/283 (22%), Positives = 116/283 (40%), Gaps = 33/283 (11%)
Query: 33 PLDTAKVRLQIQGENQAVQTARLVQYRGVLGTILTMVRTEGPCSPYNGLVAGLQRQMSFA 92
P D K+R Q+Q E + ++ +Y G+L +++ EGP + + G V + +
Sbjct: 35 PFDVIKIRFQLQHERLS-RSDPSAKYHGILQASRQILQEEGPTAFWKGHVPAQILSIGYG 93
Query: 93 SIRIGLYDSVKQ-VYTPKGADNSSLTTRILAGCTTGAMAVTCAQPTDVVKVRFQASIHLG 151
+++ ++ + + V+ D + + G MA P DV++ RF A
Sbjct: 94 AVQFLSFEMLTELVHRGSVYDAREFSVHFVCGGLAACMATLTVHPVDVLRTRFAAQ---- 149
Query: 152 PSRSDRKYSGTMDAYRTIAREEGVRGLWKGTLPNIMRNAIVNCAEVVTYDILKEKLLDYH 211
+ Y+ A T+ R EG + +KG P ++ + Y LK H
Sbjct: 150 --GEPKVYNTLRHAVGTMYRSEGPQVFYKGLAPTLIAIFPYAGLQFSCYSSLK------H 201
Query: 212 LLTDNFPC---------HFVSAFGAGFCATVVASPVDVVKTR-------YMNSPPGQ--- 252
L P + + GAG + + P+D+ K R + + GQ
Sbjct: 202 LYKWAIPAEGKKNENLQNLLCGSGAGVISKTLTYPLDLFKKRLQVGGFEHARAAFGQVRR 261
Query: 253 YFSPLDCMIKMVAQEGPTAFYKGFTPSFLRLGSWNVVMFVTYE 295
Y +DC +++ +EG F+KG +PS L+ MF +YE
Sbjct: 262 YKGLMDCAKQVLQKEGALGFFKGLSPSLLKAALSTGFMFFSYE 304
>gi|186928858 solute carrier family 25, member 19 [Homo sapiens]
Length = 320
Score = 89.0 bits (219), Expect = 5e-18
Identities = 63/196 (32%), Positives = 94/196 (47%), Gaps = 8/196 (4%)
Query: 108 PKGADNSSLTTRILAGCTTGAMAVTCAQPTDVVKVRFQASIHLGPSRSD--RKYSGTMDA 165
P G +N+ + AG +G + P DV+K+RFQ H SRSD KY G + A
Sbjct: 8 PDGRNNTKFQVAV-AGSVSGLVTRALISPFDVIKIRFQLQ-HERLSRSDPSAKYHGILQA 65
Query: 166 YRTIAREEGVRGLWKGTLPNIMRNAIVNCAEVVTYDILKEKLLDYHLLTD--NFPCHFVS 223
R I +EEG WKG +P + + + +++++L E L+ + D F HFV
Sbjct: 66 SRQILQEEGPTAFWKGHVPAQILSIGYGAVQFLSFEMLTE-LVHRGSVYDAREFSVHFVC 124
Query: 224 AFGAGFCATVVASPVDVVKTRYM-NSPPGQYFSPLDCMIKMVAQEGPTAFYKGFTPSFLR 282
A AT+ PVDV++TR+ P Y + + M EGP FYKG P+ +
Sbjct: 125 GGLAACMATLTVHPVDVLRTRFAAQGEPKVYNTLRHAVGTMYRSEGPQVFYKGLAPTLIA 184
Query: 283 LGSWNVVMFVTYEQLK 298
+ + + F Y LK
Sbjct: 185 IFPYAGLQFSCYSSLK 200
Score = 82.0 bits (201), Expect = 6e-16
Identities = 56/185 (30%), Positives = 86/185 (46%), Gaps = 16/185 (8%)
Query: 14 AVKFLGAGTAACFADLVTFPLDTAKVRLQIQGENQAVQTARLVQYRGVLGTILTMVRTEG 73
+V F+ G AAC A L P+D + R QGE + T R + TM R+EG
Sbjct: 119 SVHFVCGGLAACMATLTVHPVDVLRTRFAAQGEPKVYNTLR--------HAVGTMYRSEG 170
Query: 74 PCSPYNGLVAGLQRQMSFASIRIGLYDSVKQVY----TPKGADNSSLTTRILAGCTTGAM 129
P Y GL L +A ++ Y S+K +Y +G N +L +L G G +
Sbjct: 171 PQVFYKGLAPTLIAIFPYAGLQFSCYSSLKHLYKWAIPAEGKKNENL-QNLLCGSGAGVI 229
Query: 130 AVTCAQPTDVVKVRFQAS--IHLGPSRSD-RKYSGTMDAYRTIAREEGVRGLWKGTLPNI 186
+ T P D+ K R Q H + R+Y G MD + + ++EG G +KG P++
Sbjct: 230 SKTLTYPLDLFKKRLQVGGFEHARAAFGQVRRYKGLMDCAKQVLQKEGALGFFKGLSPSL 289
Query: 187 MRNAI 191
++ A+
Sbjct: 290 LKAAL 294
Score = 72.4 bits (176), Expect = 5e-13
Identities = 65/283 (22%), Positives = 116/283 (40%), Gaps = 33/283 (11%)
Query: 33 PLDTAKVRLQIQGENQAVQTARLVQYRGVLGTILTMVRTEGPCSPYNGLVAGLQRQMSFA 92
P D K+R Q+Q E + ++ +Y G+L +++ EGP + + G V + +
Sbjct: 35 PFDVIKIRFQLQHERLS-RSDPSAKYHGILQASRQILQEEGPTAFWKGHVPAQILSIGYG 93
Query: 93 SIRIGLYDSVKQ-VYTPKGADNSSLTTRILAGCTTGAMAVTCAQPTDVVKVRFQASIHLG 151
+++ ++ + + V+ D + + G MA P DV++ RF A
Sbjct: 94 AVQFLSFEMLTELVHRGSVYDAREFSVHFVCGGLAACMATLTVHPVDVLRTRFAAQ---- 149
Query: 152 PSRSDRKYSGTMDAYRTIAREEGVRGLWKGTLPNIMRNAIVNCAEVVTYDILKEKLLDYH 211
+ Y+ A T+ R EG + +KG P ++ + Y LK H
Sbjct: 150 --GEPKVYNTLRHAVGTMYRSEGPQVFYKGLAPTLIAIFPYAGLQFSCYSSLK------H 201
Query: 212 LLTDNFPC---------HFVSAFGAGFCATVVASPVDVVKTR-------YMNSPPGQ--- 252
L P + + GAG + + P+D+ K R + + GQ
Sbjct: 202 LYKWAIPAEGKKNENLQNLLCGSGAGVISKTLTYPLDLFKKRLQVGGFEHARAAFGQVRR 261
Query: 253 YFSPLDCMIKMVAQEGPTAFYKGFTPSFLRLGSWNVVMFVTYE 295
Y +DC +++ +EG F+KG +PS L+ MF +YE
Sbjct: 262 YKGLMDCAKQVLQKEGALGFFKGLSPSLLKAALSTGFMFFSYE 304
>gi|13375983 mitochondrial glutamate carrier 1 [Homo sapiens]
Length = 323
Score = 87.4 bits (215), Expect = 1e-17
Identities = 74/294 (25%), Positives = 114/294 (38%), Gaps = 33/294 (11%)
Query: 7 SDVPPTMAVKFLGAGTAACFADLVTFPLDTAKVRLQIQGENQAVQTARLVQYRGVLGTIL 66
+D ++ K + G A FP+D AK RLQ Q Q V Y + ++
Sbjct: 2 ADKQISLPAKLINGGIAGLIGVTCVFPIDLAKTRLQNQQNGQRV-------YTSMSDCLI 54
Query: 67 TMVRTEGPCSPYNGLVAGLQRQMSFASIRIGLYDSVKQVYTPKGADNSSLTTRILAGCTT 126
VR+EG Y G L +I++ D + + K +L +LAGC
Sbjct: 55 KTVRSEGYFGMYRGAAVNLTLVTPEKAIKLAANDFFRHQLS-KDGQKLTLLKEMLAGCGA 113
Query: 127 GAMAVTCAQPTDVVKVRFQASIHLGPSRSDRKYSGTMDAY-------------------- 166
G V P +++K++ Q + + R G + A
Sbjct: 114 GTCQVIVTTPMEMLKIQLQDAGRIAAQRKILAAQGQLSAQGGAQPSVEAPAAPRPTATQL 173
Query: 167 -RTIAREEGVRGLWKGTLPNIMRNAIVNCAEVVTYDILKEKLLDYHLLTDNFPCHFVSAF 225
R + R G+ GL+KG ++R+ + + L + F F++
Sbjct: 174 TRDLLRSRGIAGLYKGLGATLLRDVPFSVVYFPLFANLNQLGRPASEEKSPFYVSFLAGC 233
Query: 226 GAGFCATVVASPVDVVKTRYMNSPPG----QYFSPLDCMIKMVAQEGPTAFYKG 275
AG A V +P DVVKTR + G Y LDC K++ EGP+AF KG
Sbjct: 234 VAGSAAAVAVNPCDVVKTRLQSLQRGVNEDTYSGILDCARKILRHEGPSAFLKG 287
Score = 69.3 bits (168), Expect = 4e-12
Identities = 61/212 (28%), Positives = 92/212 (43%), Gaps = 28/212 (13%)
Query: 19 GAGTAACFADLVTFPLDTAKVRLQIQGENQAVQTARLVQYRGVLG--------------- 63
G G C +VT P++ K++LQ G A + +++ +G L
Sbjct: 110 GCGAGTCQV-IVTTPMEMLKIQLQDAGRIAAQR--KILAAQGQLSAQGGAQPSVEAPAAP 166
Query: 64 ----TILT--MVRTEGPCSPYNGLVAGLQRQMSFASIRIGLYDSVKQVYTPKGADNSSLT 117
T LT ++R+ G Y GL A L R + F+ + L+ ++ Q+ P + S
Sbjct: 167 RPTATQLTRDLLRSRGIAGLYKGLGATLLRDVPFSVVYFPLFANLNQLGRPASEEKSPFY 226
Query: 118 TRILAGCTTGAMAVTCAQPTDVVKVRFQASIHLGPSRSDRKYSGTMDAYRTIAREEGVRG 177
LAGC G+ A P DVVK R Q+ L ++ YSG +D R I R EG
Sbjct: 227 VSFLAGCVAGSAAAVAVNPCDVVKTRLQS---LQRGVNEDTYSGILDCARKILRHEGPSA 283
Query: 178 LWKGTLPNIMRNA-IVNCAEVVTYDILKEKLL 208
KG + A + A+VV + + E LL
Sbjct: 284 FLKGAYCRALVIAPLFGIAQVVYFLGIAESLL 315
>gi|239755176 PREDICTED: similar to solute carrier family 25, member
25 isoform 2 [Homo sapiens]
Length = 469
Score = 87.0 bits (214), Expect = 2e-17
Identities = 75/292 (25%), Positives = 129/292 (44%), Gaps = 26/292 (8%)
Query: 18 LGAGTAACFADLVTFPLDTAKVRLQIQGENQAVQTARLVQYRGVLGTILTMVRTEGPCSP 77
+ G A + T PLD KV +Q+ G++G M+R G S
Sbjct: 191 VAGGGAGAVSRTCTAPLDRLKVLMQVHASRS--------NNMGIVGGFTQMIREGGARSL 242
Query: 78 YNGLVAGLQRQMSFASIRIGLYDSVKQVYTPKGADNSSLTT--RILAGCTTGAMAVTCAQ 135
+ G + + ++I+ Y+ +K++ G+D +L R++AG GA+A +
Sbjct: 243 WRGNGINVLKIAPESAIKFMAYEQIKRLV---GSDQETLRIHERLVAGSLAGAIAQSSIY 299
Query: 136 PTDVVKVRFQASIHLGPSRSDRKYSGTMDAYRTIAREEGVRGLWKGTLPNIMRNAIVNCA 195
P +V+K R R +YSG +D R I EGV +KG +PN++
Sbjct: 300 PMEVLKTRMAL-------RKTGQYSGMLDCARRILAREGVAAFYKGYVPNMLGIIPYAGI 352
Query: 196 EVVTYDILKEKLLDYHLLTDNFPCHFVS-AFG--AGFCATVVASPVDVVKTRYMN--SPP 250
++ Y+ LK L ++ + P FV A G + C + + P+ +V+TR S
Sbjct: 353 DLAVYETLKNAWLQHYAVNSADPGVFVLLACGTMSSTCGQLASYPLALVRTRMQAQASIE 412
Query: 251 GQYFSPLDCMIKMVAQ-EGPTAFYKGFTPSFLRLGSWNVVMFVTYEQLKRAL 301
G + + K + + EG Y+G P+F+++ + +V YE LK L
Sbjct: 413 GAPEVTMSSLFKHILRTEGAFGLYRGLAPNFMKVIPAVSISYVVYENLKITL 464
Score = 86.3 bits (212), Expect = 3e-17
Identities = 57/184 (30%), Positives = 93/184 (50%), Gaps = 7/184 (3%)
Query: 120 ILAGCTTGAMAVTCAQPTDVVKVRFQASIHLGPSRSDRKYSGTMDAYRTIAREEGVRGLW 179
++AG GA++ TC P D +KV Q +H S + G + + + RE G R LW
Sbjct: 190 LVAGGGAGAVSRTCTAPLDRLKVLMQ--VHASRSNN----MGIVGGFTQMIREGGARSLW 243
Query: 180 KGTLPNIMRNAIVNCAEVVTYDILKEKLLDYHLLTDNFPCHFVSAFGAGFCATVVASPVD 239
+G N+++ A + + + Y+ +K +L+ T V+ AG A P++
Sbjct: 244 RGNGINVLKIAPESAIKFMAYEQIK-RLVGSDQETLRIHERLVAGSLAGAIAQSSIYPME 302
Query: 240 VVKTRYMNSPPGQYFSPLDCMIKMVAQEGPTAFYKGFTPSFLRLGSWNVVMFVTYEQLKR 299
V+KTR GQY LDC +++A+EG AFYKG+ P+ L + + + YE LK
Sbjct: 303 VLKTRMALRKTGQYSGMLDCARRILAREGVAAFYKGYVPNMLGIIPYAGIDLAVYETLKN 362
Query: 300 ALMK 303
A ++
Sbjct: 363 AWLQ 366
Score = 57.4 bits (137), Expect = 2e-08
Identities = 50/196 (25%), Positives = 84/196 (42%), Gaps = 24/196 (12%)
Query: 16 KFLGAGTAACFADLVTFPLDTAKVRLQIQGENQAVQTARLVQYRGVLGTILTMVRTEGPC 75
+ + A A +P++ K R+ ++ + QY G+L ++ EG
Sbjct: 283 RLVAGSLAGAIAQSSIYPMEVLKTRMALR---------KTGQYSGMLDCARRILAREGVA 333
Query: 76 SPYNGLVAGLQRQMSFASIRIGLYDSVKQVYTPKGADNSS-LTTRILAGCTTGAMAVTCA 134
+ Y G V + + +A I + +Y+++K + A NS+ +L C G M+ TC
Sbjct: 334 AFYKGYVPNMLGIIPYAGIDLAVYETLKNAWLQHYAVNSADPGVFVLLAC--GTMSSTCG 391
Query: 135 Q----PTDVVKVRF--QASIHLGPSRSDRKYSGTMDAYRTIAREEGVRGLWKGTLPNIMR 188
Q P +V+ R QASI P + ++ I R EG GL++G PN M+
Sbjct: 392 QLASYPLALVRTRMQAQASIEGAPEVT------MSSLFKHILRTEGAFGLYRGLAPNFMK 445
Query: 189 NAIVNCAEVVTYDILK 204
V Y+ LK
Sbjct: 446 VIPAVSISYVVYENLK 461
>gi|239755174 PREDICTED: similar to solute carrier family 25, member
25 isoform 1 [Homo sapiens]
Length = 503
Score = 87.0 bits (214), Expect = 2e-17
Identities = 75/292 (25%), Positives = 129/292 (44%), Gaps = 26/292 (8%)
Query: 18 LGAGTAACFADLVTFPLDTAKVRLQIQGENQAVQTARLVQYRGVLGTILTMVRTEGPCSP 77
+ G A + T PLD KV +Q+ G++G M+R G S
Sbjct: 225 VAGGGAGAVSRTCTAPLDRLKVLMQVHASRS--------NNMGIVGGFTQMIREGGARSL 276
Query: 78 YNGLVAGLQRQMSFASIRIGLYDSVKQVYTPKGADNSSLTT--RILAGCTTGAMAVTCAQ 135
+ G + + ++I+ Y+ +K++ G+D +L R++AG GA+A +
Sbjct: 277 WRGNGINVLKIAPESAIKFMAYEQIKRLV---GSDQETLRIHERLVAGSLAGAIAQSSIY 333
Query: 136 PTDVVKVRFQASIHLGPSRSDRKYSGTMDAYRTIAREEGVRGLWKGTLPNIMRNAIVNCA 195
P +V+K R R +YSG +D R I EGV +KG +PN++
Sbjct: 334 PMEVLKTRMAL-------RKTGQYSGMLDCARRILAREGVAAFYKGYVPNMLGIIPYAGI 386
Query: 196 EVVTYDILKEKLLDYHLLTDNFPCHFVS-AFG--AGFCATVVASPVDVVKTRYMN--SPP 250
++ Y+ LK L ++ + P FV A G + C + + P+ +V+TR S
Sbjct: 387 DLAVYETLKNAWLQHYAVNSADPGVFVLLACGTMSSTCGQLASYPLALVRTRMQAQASIE 446
Query: 251 GQYFSPLDCMIKMVAQ-EGPTAFYKGFTPSFLRLGSWNVVMFVTYEQLKRAL 301
G + + K + + EG Y+G P+F+++ + +V YE LK L
Sbjct: 447 GAPEVTMSSLFKHILRTEGAFGLYRGLAPNFMKVIPAVSISYVVYENLKITL 498
Score = 86.3 bits (212), Expect = 3e-17
Identities = 57/184 (30%), Positives = 93/184 (50%), Gaps = 7/184 (3%)
Query: 120 ILAGCTTGAMAVTCAQPTDVVKVRFQASIHLGPSRSDRKYSGTMDAYRTIAREEGVRGLW 179
++AG GA++ TC P D +KV Q +H S + G + + + RE G R LW
Sbjct: 224 LVAGGGAGAVSRTCTAPLDRLKVLMQ--VHASRSNN----MGIVGGFTQMIREGGARSLW 277
Query: 180 KGTLPNIMRNAIVNCAEVVTYDILKEKLLDYHLLTDNFPCHFVSAFGAGFCATVVASPVD 239
+G N+++ A + + + Y+ +K +L+ T V+ AG A P++
Sbjct: 278 RGNGINVLKIAPESAIKFMAYEQIK-RLVGSDQETLRIHERLVAGSLAGAIAQSSIYPME 336
Query: 240 VVKTRYMNSPPGQYFSPLDCMIKMVAQEGPTAFYKGFTPSFLRLGSWNVVMFVTYEQLKR 299
V+KTR GQY LDC +++A+EG AFYKG+ P+ L + + + YE LK
Sbjct: 337 VLKTRMALRKTGQYSGMLDCARRILAREGVAAFYKGYVPNMLGIIPYAGIDLAVYETLKN 396
Query: 300 ALMK 303
A ++
Sbjct: 397 AWLQ 400
Score = 57.4 bits (137), Expect = 2e-08
Identities = 50/196 (25%), Positives = 84/196 (42%), Gaps = 24/196 (12%)
Query: 16 KFLGAGTAACFADLVTFPLDTAKVRLQIQGENQAVQTARLVQYRGVLGTILTMVRTEGPC 75
+ + A A +P++ K R+ ++ + QY G+L ++ EG
Sbjct: 317 RLVAGSLAGAIAQSSIYPMEVLKTRMALR---------KTGQYSGMLDCARRILAREGVA 367
Query: 76 SPYNGLVAGLQRQMSFASIRIGLYDSVKQVYTPKGADNSS-LTTRILAGCTTGAMAVTCA 134
+ Y G V + + +A I + +Y+++K + A NS+ +L C G M+ TC
Sbjct: 368 AFYKGYVPNMLGIIPYAGIDLAVYETLKNAWLQHYAVNSADPGVFVLLAC--GTMSSTCG 425
Query: 135 Q----PTDVVKVRF--QASIHLGPSRSDRKYSGTMDAYRTIAREEGVRGLWKGTLPNIMR 188
Q P +V+ R QASI P + ++ I R EG GL++G PN M+
Sbjct: 426 QLASYPLALVRTRMQAQASIEGAPEVT------MSSLFKHILRTEGAFGLYRGLAPNFMK 479
Query: 189 NAIVNCAEVVTYDILK 204
V Y+ LK
Sbjct: 480 VIPAVSISYVVYENLK 495
>gi|56699407 solute carrier family 25, member 25 isoform c [Homo
sapiens]
Length = 489
Score = 87.0 bits (214), Expect = 2e-17
Identities = 75/292 (25%), Positives = 129/292 (44%), Gaps = 26/292 (8%)
Query: 18 LGAGTAACFADLVTFPLDTAKVRLQIQGENQAVQTARLVQYRGVLGTILTMVRTEGPCSP 77
+ G A + T PLD KV +Q+ G++G M+R G S
Sbjct: 211 VAGGGAGAVSRTCTAPLDRLKVLMQVHASRS--------NNMGIVGGFTQMIREGGARSL 262
Query: 78 YNGLVAGLQRQMSFASIRIGLYDSVKQVYTPKGADNSSLTT--RILAGCTTGAMAVTCAQ 135
+ G + + ++I+ Y+ +K++ G+D +L R++AG GA+A +
Sbjct: 263 WRGNGINVLKIAPESAIKFMAYEQIKRLV---GSDQETLRIHERLVAGSLAGAIAQSSIY 319
Query: 136 PTDVVKVRFQASIHLGPSRSDRKYSGTMDAYRTIAREEGVRGLWKGTLPNIMRNAIVNCA 195
P +V+K R R +YSG +D R I EGV +KG +PN++
Sbjct: 320 PMEVLKTRMAL-------RKTGQYSGMLDCARRILAREGVAAFYKGYVPNMLGIIPYAGI 372
Query: 196 EVVTYDILKEKLLDYHLLTDNFPCHFVS-AFG--AGFCATVVASPVDVVKTRYMN--SPP 250
++ Y+ LK L ++ + P FV A G + C + + P+ +V+TR S
Sbjct: 373 DLAVYETLKNAWLQHYAVNSADPGVFVLLACGTMSSTCGQLASYPLALVRTRMQAQASIE 432
Query: 251 GQYFSPLDCMIKMVAQ-EGPTAFYKGFTPSFLRLGSWNVVMFVTYEQLKRAL 301
G + + K + + EG Y+G P+F+++ + +V YE LK L
Sbjct: 433 GAPEVTMSSLFKHILRTEGAFGLYRGLAPNFMKVIPAVSISYVVYENLKITL 484
Score = 86.3 bits (212), Expect = 3e-17
Identities = 57/184 (30%), Positives = 93/184 (50%), Gaps = 7/184 (3%)
Query: 120 ILAGCTTGAMAVTCAQPTDVVKVRFQASIHLGPSRSDRKYSGTMDAYRTIAREEGVRGLW 179
++AG GA++ TC P D +KV Q +H S + G + + + RE G R LW
Sbjct: 210 LVAGGGAGAVSRTCTAPLDRLKVLMQ--VHASRSNN----MGIVGGFTQMIREGGARSLW 263
Query: 180 KGTLPNIMRNAIVNCAEVVTYDILKEKLLDYHLLTDNFPCHFVSAFGAGFCATVVASPVD 239
+G N+++ A + + + Y+ +K +L+ T V+ AG A P++
Sbjct: 264 RGNGINVLKIAPESAIKFMAYEQIK-RLVGSDQETLRIHERLVAGSLAGAIAQSSIYPME 322
Query: 240 VVKTRYMNSPPGQYFSPLDCMIKMVAQEGPTAFYKGFTPSFLRLGSWNVVMFVTYEQLKR 299
V+KTR GQY LDC +++A+EG AFYKG+ P+ L + + + YE LK
Sbjct: 323 VLKTRMALRKTGQYSGMLDCARRILAREGVAAFYKGYVPNMLGIIPYAGIDLAVYETLKN 382
Query: 300 ALMK 303
A ++
Sbjct: 383 AWLQ 386
Score = 57.4 bits (137), Expect = 2e-08
Identities = 50/196 (25%), Positives = 84/196 (42%), Gaps = 24/196 (12%)
Query: 16 KFLGAGTAACFADLVTFPLDTAKVRLQIQGENQAVQTARLVQYRGVLGTILTMVRTEGPC 75
+ + A A +P++ K R+ ++ + QY G+L ++ EG
Sbjct: 303 RLVAGSLAGAIAQSSIYPMEVLKTRMALR---------KTGQYSGMLDCARRILAREGVA 353
Query: 76 SPYNGLVAGLQRQMSFASIRIGLYDSVKQVYTPKGADNSS-LTTRILAGCTTGAMAVTCA 134
+ Y G V + + +A I + +Y+++K + A NS+ +L C G M+ TC
Sbjct: 354 AFYKGYVPNMLGIIPYAGIDLAVYETLKNAWLQHYAVNSADPGVFVLLAC--GTMSSTCG 411
Query: 135 Q----PTDVVKVRF--QASIHLGPSRSDRKYSGTMDAYRTIAREEGVRGLWKGTLPNIMR 188
Q P +V+ R QASI P + ++ I R EG GL++G PN M+
Sbjct: 412 QLASYPLALVRTRMQAQASIEGAPEVT------MSSLFKHILRTEGAFGLYRGLAPNFMK 465
Query: 189 NAIVNCAEVVTYDILK 204
V Y+ LK
Sbjct: 466 VIPAVSISYVVYENLK 481
>gi|56699401 solute carrier family 25, member 25 isoform a [Homo
sapiens]
Length = 469
Score = 87.0 bits (214), Expect = 2e-17
Identities = 75/292 (25%), Positives = 129/292 (44%), Gaps = 26/292 (8%)
Query: 18 LGAGTAACFADLVTFPLDTAKVRLQIQGENQAVQTARLVQYRGVLGTILTMVRTEGPCSP 77
+ G A + T PLD KV +Q+ G++G M+R G S
Sbjct: 191 VAGGGAGAVSRTCTAPLDRLKVLMQVHASRS--------NNMGIVGGFTQMIREGGARSL 242
Query: 78 YNGLVAGLQRQMSFASIRIGLYDSVKQVYTPKGADNSSLTT--RILAGCTTGAMAVTCAQ 135
+ G + + ++I+ Y+ +K++ G+D +L R++AG GA+A +
Sbjct: 243 WRGNGINVLKIAPESAIKFMAYEQIKRLV---GSDQETLRIHERLVAGSLAGAIAQSSIY 299
Query: 136 PTDVVKVRFQASIHLGPSRSDRKYSGTMDAYRTIAREEGVRGLWKGTLPNIMRNAIVNCA 195
P +V+K R R +YSG +D R I EGV +KG +PN++
Sbjct: 300 PMEVLKTRMAL-------RKTGQYSGMLDCARRILAREGVAAFYKGYVPNMLGIIPYAGI 352
Query: 196 EVVTYDILKEKLLDYHLLTDNFPCHFVS-AFG--AGFCATVVASPVDVVKTRYMN--SPP 250
++ Y+ LK L ++ + P FV A G + C + + P+ +V+TR S
Sbjct: 353 DLAVYETLKNAWLQHYAVNSADPGVFVLLACGTMSSTCGQLASYPLALVRTRMQAQASIE 412
Query: 251 GQYFSPLDCMIKMVAQ-EGPTAFYKGFTPSFLRLGSWNVVMFVTYEQLKRAL 301
G + + K + + EG Y+G P+F+++ + +V YE LK L
Sbjct: 413 GAPEVTMSSLFKHILRTEGAFGLYRGLAPNFMKVIPAVSISYVVYENLKITL 464
Score = 86.3 bits (212), Expect = 3e-17
Identities = 57/184 (30%), Positives = 93/184 (50%), Gaps = 7/184 (3%)
Query: 120 ILAGCTTGAMAVTCAQPTDVVKVRFQASIHLGPSRSDRKYSGTMDAYRTIAREEGVRGLW 179
++AG GA++ TC P D +KV Q +H S + G + + + RE G R LW
Sbjct: 190 LVAGGGAGAVSRTCTAPLDRLKVLMQ--VHASRSNN----MGIVGGFTQMIREGGARSLW 243
Query: 180 KGTLPNIMRNAIVNCAEVVTYDILKEKLLDYHLLTDNFPCHFVSAFGAGFCATVVASPVD 239
+G N+++ A + + + Y+ +K +L+ T V+ AG A P++
Sbjct: 244 RGNGINVLKIAPESAIKFMAYEQIK-RLVGSDQETLRIHERLVAGSLAGAIAQSSIYPME 302
Query: 240 VVKTRYMNSPPGQYFSPLDCMIKMVAQEGPTAFYKGFTPSFLRLGSWNVVMFVTYEQLKR 299
V+KTR GQY LDC +++A+EG AFYKG+ P+ L + + + YE LK
Sbjct: 303 VLKTRMALRKTGQYSGMLDCARRILAREGVAAFYKGYVPNMLGIIPYAGIDLAVYETLKN 362
Query: 300 ALMK 303
A ++
Sbjct: 363 AWLQ 366
Score = 57.4 bits (137), Expect = 2e-08
Identities = 50/196 (25%), Positives = 84/196 (42%), Gaps = 24/196 (12%)
Query: 16 KFLGAGTAACFADLVTFPLDTAKVRLQIQGENQAVQTARLVQYRGVLGTILTMVRTEGPC 75
+ + A A +P++ K R+ ++ + QY G+L ++ EG
Sbjct: 283 RLVAGSLAGAIAQSSIYPMEVLKTRMALR---------KTGQYSGMLDCARRILAREGVA 333
Query: 76 SPYNGLVAGLQRQMSFASIRIGLYDSVKQVYTPKGADNSS-LTTRILAGCTTGAMAVTCA 134
+ Y G V + + +A I + +Y+++K + A NS+ +L C G M+ TC
Sbjct: 334 AFYKGYVPNMLGIIPYAGIDLAVYETLKNAWLQHYAVNSADPGVFVLLAC--GTMSSTCG 391
Query: 135 Q----PTDVVKVRF--QASIHLGPSRSDRKYSGTMDAYRTIAREEGVRGLWKGTLPNIMR 188
Q P +V+ R QASI P + ++ I R EG GL++G PN M+
Sbjct: 392 QLASYPLALVRTRMQAQASIEGAPEVT------MSSLFKHILRTEGAFGLYRGLAPNFMK 445
Query: 189 NAIVNCAEVVTYDILK 204
V Y+ LK
Sbjct: 446 VIPAVSISYVVYENLK 461
>gi|56699405 solute carrier family 25, member 25 isoform d [Homo
sapiens]
Length = 366
Score = 87.0 bits (214), Expect = 2e-17
Identities = 75/292 (25%), Positives = 129/292 (44%), Gaps = 26/292 (8%)
Query: 18 LGAGTAACFADLVTFPLDTAKVRLQIQGENQAVQTARLVQYRGVLGTILTMVRTEGPCSP 77
+ G A + T PLD KV +Q+ G++G M+R G S
Sbjct: 88 VAGGGAGAVSRTCTAPLDRLKVLMQVHASRS--------NNMGIVGGFTQMIREGGARSL 139
Query: 78 YNGLVAGLQRQMSFASIRIGLYDSVKQVYTPKGADNSSLTT--RILAGCTTGAMAVTCAQ 135
+ G + + ++I+ Y+ +K++ G+D +L R++AG GA+A +
Sbjct: 140 WRGNGINVLKIAPESAIKFMAYEQIKRLV---GSDQETLRIHERLVAGSLAGAIAQSSIY 196
Query: 136 PTDVVKVRFQASIHLGPSRSDRKYSGTMDAYRTIAREEGVRGLWKGTLPNIMRNAIVNCA 195
P +V+K R R +YSG +D R I EGV +KG +PN++
Sbjct: 197 PMEVLKTRMAL-------RKTGQYSGMLDCARRILAREGVAAFYKGYVPNMLGIIPYAGI 249
Query: 196 EVVTYDILKEKLLDYHLLTDNFPCHFVS-AFG--AGFCATVVASPVDVVKTRYMN--SPP 250
++ Y+ LK L ++ + P FV A G + C + + P+ +V+TR S
Sbjct: 250 DLAVYETLKNAWLQHYAVNSADPGVFVLLACGTMSSTCGQLASYPLALVRTRMQAQASIE 309
Query: 251 GQYFSPLDCMIKMVAQ-EGPTAFYKGFTPSFLRLGSWNVVMFVTYEQLKRAL 301
G + + K + + EG Y+G P+F+++ + +V YE LK L
Sbjct: 310 GAPEVTMSSLFKHILRTEGAFGLYRGLAPNFMKVIPAVSISYVVYENLKITL 361
Score = 86.3 bits (212), Expect = 3e-17
Identities = 57/184 (30%), Positives = 93/184 (50%), Gaps = 7/184 (3%)
Query: 120 ILAGCTTGAMAVTCAQPTDVVKVRFQASIHLGPSRSDRKYSGTMDAYRTIAREEGVRGLW 179
++AG GA++ TC P D +KV Q +H S + G + + + RE G R LW
Sbjct: 87 LVAGGGAGAVSRTCTAPLDRLKVLMQ--VHASRSNN----MGIVGGFTQMIREGGARSLW 140
Query: 180 KGTLPNIMRNAIVNCAEVVTYDILKEKLLDYHLLTDNFPCHFVSAFGAGFCATVVASPVD 239
+G N+++ A + + + Y+ +K +L+ T V+ AG A P++
Sbjct: 141 RGNGINVLKIAPESAIKFMAYEQIK-RLVGSDQETLRIHERLVAGSLAGAIAQSSIYPME 199
Query: 240 VVKTRYMNSPPGQYFSPLDCMIKMVAQEGPTAFYKGFTPSFLRLGSWNVVMFVTYEQLKR 299
V+KTR GQY LDC +++A+EG AFYKG+ P+ L + + + YE LK
Sbjct: 200 VLKTRMALRKTGQYSGMLDCARRILAREGVAAFYKGYVPNMLGIIPYAGIDLAVYETLKN 259
Query: 300 ALMK 303
A ++
Sbjct: 260 AWLQ 263
Score = 57.4 bits (137), Expect = 2e-08
Identities = 50/196 (25%), Positives = 84/196 (42%), Gaps = 24/196 (12%)
Query: 16 KFLGAGTAACFADLVTFPLDTAKVRLQIQGENQAVQTARLVQYRGVLGTILTMVRTEGPC 75
+ + A A +P++ K R+ ++ + QY G+L ++ EG
Sbjct: 180 RLVAGSLAGAIAQSSIYPMEVLKTRMALR---------KTGQYSGMLDCARRILAREGVA 230
Query: 76 SPYNGLVAGLQRQMSFASIRIGLYDSVKQVYTPKGADNSS-LTTRILAGCTTGAMAVTCA 134
+ Y G V + + +A I + +Y+++K + A NS+ +L C G M+ TC
Sbjct: 231 AFYKGYVPNMLGIIPYAGIDLAVYETLKNAWLQHYAVNSADPGVFVLLAC--GTMSSTCG 288
Query: 135 Q----PTDVVKVRF--QASIHLGPSRSDRKYSGTMDAYRTIAREEGVRGLWKGTLPNIMR 188
Q P +V+ R QASI P + ++ I R EG GL++G PN M+
Sbjct: 289 QLASYPLALVRTRMQAQASIEGAPEVT------MSSLFKHILRTEGAFGLYRGLAPNFMK 342
Query: 189 NAIVNCAEVVTYDILK 204
V Y+ LK
Sbjct: 343 VIPAVSISYVVYENLK 358
>gi|13899342 solute carrier [Homo sapiens]
Length = 315
Score = 87.0 bits (214), Expect = 2e-17
Identities = 73/287 (25%), Positives = 118/287 (41%), Gaps = 33/287 (11%)
Query: 12 TMAVKFLGAGTAACFADLVTFPLDTAKVRLQIQGENQAVQTARLVQYRGVLGTILTMVRT 71
++ K + G A FP+D AK RLQ Q Y+G++ ++ R
Sbjct: 7 SITAKLINGGVAGLVGVTCVFPIDLAKTRLQNQHGK--------AMYKGMIDCLMKTARA 58
Query: 72 EGPCSPYNGLVAGLQRQMSFASIRIGLYDSVKQVYTPKGADNSSLTTRILAGCTTGAMAV 131
EG Y G L +I++ D +++ G + L +LAGC G V
Sbjct: 59 EGFFGMYRGAAVNLTLVTPEKAIKLAANDFFRRLLMEDGMQRN-LKMEMLAGCGAGMCQV 117
Query: 132 TCAQPTDVVKVRFQASIHL-------------------GPSRSDRKYSGTMDAYRTIARE 172
P +++K++ Q + L G + + R+ S T+ A+ + R
Sbjct: 118 VVTCPMEMLKIQLQDAGRLAVHHQGSASAPSTSRSYTTGSASTHRRPSATLIAWELL-RT 176
Query: 173 EGVRGLWKGTLPNIMRNAIVNCAEVVTYDILKEKLLDYHLLTDNFPCHFVSAFGAGFCAT 232
+G+ GL++G ++R+ + + L + +F FVS AG A
Sbjct: 177 QGLAGLYRGLGATLLRDIPFSIIYFPLFANLNNLGFNELAGKASFAHSFVSGCVAGSIAA 236
Query: 233 VVASPVDVVKTRYMNSPPG----QYFSPLDCMIKMVAQEGPTAFYKG 275
V +P+DV+KTR G Y DC K+ QEGP+AF KG
Sbjct: 237 VAVTPLDVLKTRIQTLKKGLGEDMYSGITDCARKLWIQEGPSAFMKG 283
Score = 35.0 bits (79), Expect = 0.086
Identities = 21/83 (25%), Positives = 33/83 (39%), Gaps = 1/83 (1%)
Query: 227 AGFCATVVASPVDVVKTRYMNSP-PGQYFSPLDCMIKMVAQEGPTAFYKGFTPSFLRLGS 285
AG P+D+ KTR N Y +DC++K EG Y+G + +
Sbjct: 18 AGLVGVTCVFPIDLAKTRLQNQHGKAMYKGMIDCLMKTARAEGFFGMYRGAAVNLTLVTP 77
Query: 286 WNVVMFVTYEQLKRALMKVQMLR 308
+ + +R LM+ M R
Sbjct: 78 EKAIKLAANDFFRRLLMEDGMQR 100
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.323 0.136 0.410
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 11,265,189
Number of Sequences: 37866
Number of extensions: 453937
Number of successful extensions: 1372
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 67
Number of HSP's successfully gapped in prelim test: 8
Number of HSP's that attempted gapping in prelim test: 750
Number of HSP's gapped (non-prelim): 222
length of query: 312
length of database: 18,247,518
effective HSP length: 102
effective length of query: 210
effective length of database: 14,385,186
effective search space: 3020889060
effective search space used: 3020889060
T: 11
A: 40
X1: 16 ( 7.5 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (22.0 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.