Guide to the Human Genome
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Search of human proteins with 4507513

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|4507513 tissue inhibitor of metalloproteinase 3 precursor
[Homo sapiens]
         (211 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|4507513 tissue inhibitor of metalloproteinase 3 precursor [Ho...   463   e-131
gi|4507515 tissue inhibitor of metalloproteinase 4 precursor [Ho...   206   2e-53
gi|4507511 TIMP metallopeptidase inhibitor 2 precursor [Homo sap...   197   7e-51
gi|4507509 tissue inhibitor of metalloproteinase 1 precursor [Ho...   149   2e-36
gi|254028267 myosin 1H [Homo sapiens]                                  37   0.009
gi|209571555 von Willebrand factor D and EGF domains [Homo sapiens]    31   0.67 
gi|103472033 fucosyltransferase 6 [Homo sapiens]                       29   2.6  
gi|4503815 fucosyltransferase 6 [Homo sapiens]                         29   2.6  
gi|55741659 zinc finger protein 14-like [Homo sapiens]                 29   2.6  
gi|225703106 tudor domain containing 3 isoform 1 [Homo sapiens]        28   5.7  
gi|143770880 laminin, beta 4 [Homo sapiens]                            27   9.7  

>gi|4507513 tissue inhibitor of metalloproteinase 3 precursor [Homo
           sapiens]
          Length = 211

 Score =  463 bits (1191), Expect = e-131
 Identities = 211/211 (100%), Positives = 211/211 (100%)

Query: 1   MTPWLGLIVLLGSWSLGDWGAEACTCSPSHPQDAFCNSDIVIRAKVVGKKLVKEGPFGTL 60
           MTPWLGLIVLLGSWSLGDWGAEACTCSPSHPQDAFCNSDIVIRAKVVGKKLVKEGPFGTL
Sbjct: 1   MTPWLGLIVLLGSWSLGDWGAEACTCSPSHPQDAFCNSDIVIRAKVVGKKLVKEGPFGTL 60

Query: 61  VYTIKQMKMYRGFTKMPHVQYIHTEASESLCGLKLEVNKYQYLLTGRVYDGKMYTGLCNF 120
           VYTIKQMKMYRGFTKMPHVQYIHTEASESLCGLKLEVNKYQYLLTGRVYDGKMYTGLCNF
Sbjct: 61  VYTIKQMKMYRGFTKMPHVQYIHTEASESLCGLKLEVNKYQYLLTGRVYDGKMYTGLCNF 120

Query: 121 VERWDQLTLSQRKGLNYRYHLGCNCKIKSCYYLPCFVTSKNECLWTDMLSNFGYPGYQSK 180
           VERWDQLTLSQRKGLNYRYHLGCNCKIKSCYYLPCFVTSKNECLWTDMLSNFGYPGYQSK
Sbjct: 121 VERWDQLTLSQRKGLNYRYHLGCNCKIKSCYYLPCFVTSKNECLWTDMLSNFGYPGYQSK 180

Query: 181 HYACIRQKGGYCSWYRGWAPPDKSIINATDP 211
           HYACIRQKGGYCSWYRGWAPPDKSIINATDP
Sbjct: 181 HYACIRQKGGYCSWYRGWAPPDKSIINATDP 211


>gi|4507515 tissue inhibitor of metalloproteinase 4 precursor [Homo
           sapiens]
          Length = 224

 Score =  206 bits (523), Expect = 2e-53
 Identities = 103/214 (48%), Positives = 139/214 (64%), Gaps = 11/214 (5%)

Query: 5   LGLIVLLGSWSLGDWGAEACTCSPSHPQDAFCNSDIVIRAKVVGKKLVKEG--PFGT--- 59
           L L+ LL    LG    EAC+C+P+HPQ   C+S +VIRAK+  +K+V     P  T   
Sbjct: 15  LRLLALLRPPGLG----EACSCAPAHPQQHICHSALVIRAKISSEKVVPASADPADTEKM 70

Query: 60  LVYTIKQMKMYRGFTKMPHVQYIHTEASESLCGLKLEVNKY-QYLLTGRVY-DGKMYTGL 117
           L Y IKQ+KM++GF K+  VQYI+T    SLCG+KLE N   QYLLTG+V  DGK++  L
Sbjct: 71  LRYEIKQIKMFKGFEKVKDVQYIYTPFDSSLCGVKLEANSQKQYLLTGQVLSDGKVFIHL 130

Query: 118 CNFVERWDQLTLSQRKGLNYRYHLGCNCKIKSCYYLPCFVTSKNECLWTDMLSNFGYPGY 177
           CN++E W+ L+L QR+ LN+ YHL C C+I +CY +PC +++ NECLWTD L      GY
Sbjct: 131 CNYIEPWEDLSLVQRESLNHHYHLNCGCQITTCYTVPCTISAPNECLWTDWLLERKLYGY 190

Query: 178 QSKHYACIRQKGGYCSWYRGWAPPDKSIINATDP 211
           Q++HY C++   G CSWYRG  P  K  ++   P
Sbjct: 191 QAQHYVCMKHVDGTCSWYRGHLPLRKEFVDIVQP 224


>gi|4507511 TIMP metallopeptidase inhibitor 2 precursor [Homo
           sapiens]
          Length = 220

 Score =  197 bits (500), Expect = 7e-51
 Identities = 90/199 (45%), Positives = 134/199 (67%), Gaps = 10/199 (5%)

Query: 21  AEACTCSPSHPQDAFCNSDIVIRAKVVGKKLVKEG------PFGTLVYTIKQMKMYRGFT 74
           A+AC+CSP HPQ AFCN+D+VIRAK V +K V  G      P   + Y IKQ+KM++G  
Sbjct: 24  ADACSCSPVHPQQAFCNADVVIRAKAVSEKEVDSGNDIYGNPIKRIQYEIKQIKMFKGPE 83

Query: 75  KMPHVQYIHTEASESLCGLKLEVN-KYQYLLTGRVY-DGKMYTGLCNFVERWDQLTLSQR 132
           K   +++I+T  S ++CG+ L+V  K +YL+ G+   DGKM+  LC+F+  WD L+ +Q+
Sbjct: 84  K--DIEFIYTAPSSAVCGVSLDVGGKKEYLIAGKAEGDGKMHITLCDFIVPWDTLSTTQK 141

Query: 133 KGLNYRYHLGCNCKIKSCYYLPCFVTSKNECLWTDMLSNFGYPGYQSKHYACIRQKGGYC 192
           K LN+RY +GC CKI  C  +PC+++S +ECLW D ++     G+Q+K +ACI++  G C
Sbjct: 142 KSLNHRYQMGCECKITRCPMIPCYISSPDECLWMDWVTEKNINGHQAKFFACIKRSDGSC 201

Query: 193 SWYRGWAPPDKSIINATDP 211
           +WYRG APP +  ++  DP
Sbjct: 202 AWYRGAAPPKQEFLDIEDP 220


>gi|4507509 tissue inhibitor of metalloproteinase 1 precursor [Homo
           sapiens]
          Length = 207

 Score =  149 bits (375), Expect = 2e-36
 Identities = 76/195 (38%), Positives = 114/195 (58%), Gaps = 11/195 (5%)

Query: 6   GLIVLLGSWSLGDWGAEACTCSPSHPQDAFCNSDIVIRAKVVGKKLVKEGPFGTLVYTIK 65
           G+++LL  W +    + ACTC P HPQ AFCNSD+VIRAK VG   V +       Y IK
Sbjct: 10  GILLLL--WLIAP--SRACTCVPPHPQTAFCNSDLVIRAKFVGTPEVNQTTLYQR-YEIK 64

Query: 66  QMKMYRGFTKM---PHVQYIHTEASESLCGL--KLEVNKYQYLLTGRVYDGKMYTGLCNF 120
             KMY+GF  +     +++++T A ES+CG   +      ++L+ G++ DG ++   C+F
Sbjct: 65  MTKMYKGFQALGDAADIRFVYTPAMESVCGYFHRSHNRSEEFLIAGKLQDGLLHITTCSF 124

Query: 121 VERWDQLTLSQRKGLNYRYHLGCN-CKIKSCYYLPCFVTSKNECLWTDMLSNFGYPGYQS 179
           V  W+ L+L+QR+G    Y +GC  C +  C  +PC + S   CLWTD L      G+QS
Sbjct: 125 VAPWNSLSLAQRRGFTKTYTVGCEECTVFPCLSIPCKLQSGTHCLWTDQLLQGSEKGFQS 184

Query: 180 KHYACIRQKGGYCSW 194
           +H AC+ ++ G C+W
Sbjct: 185 RHLACLPREPGLCTW 199


>gi|254028267 myosin 1H [Homo sapiens]
          Length = 1022

 Score = 37.4 bits (85), Expect = 0.009
 Identities = 24/70 (34%), Positives = 36/70 (51%), Gaps = 7/70 (10%)

Query: 47  VGKKLVKEGPFGTL-VYTIKQMKMYRG---FTKMPHVQYIHTEASESLCGLKLEVNKYQY 102
           +G  LV   P+  L +YT+ QM++Y+G   F   PHV  I   A   +C    E+N +  
Sbjct: 45  IGTLLVSVNPYQELGIYTVSQMELYQGVNFFELPPHVYAIADNAYRMMCA---ELNNHFI 101

Query: 103 LLTGRVYDGK 112
           L++G    GK
Sbjct: 102 LISGESGAGK 111


>gi|209571555 von Willebrand factor D and EGF domains [Homo sapiens]
          Length = 1590

 Score = 31.2 bits (69), Expect = 0.67
 Identities = 23/85 (27%), Positives = 38/85 (44%), Gaps = 6/85 (7%)

Query: 73  FTKMPHVQYIHTEASESLCGLKLEVNKYQYLLTGRVYDGKMYTG---LCNFVERWDQ--- 126
           F + PHVQ +  E+ E   G KL+         G+ Y  ++ +    +C+     DQ   
Sbjct: 272 FLENPHVQSVAIESQEFFAGFKLQPELSTISEDGKEYYLRIESTVPIICSEFSELDQECK 331

Query: 127 LTLSQRKGLNYRYHLGCNCKIKSCY 151
           ++L  +     R HLG N  + SC+
Sbjct: 332 ISLKLKTIGQGREHLGLNLALSSCH 356


>gi|103472033 fucosyltransferase 6 [Homo sapiens]
          Length = 359

 Score = 29.3 bits (64), Expect = 2.6
 Identities = 18/72 (25%), Positives = 29/72 (40%), Gaps = 7/72 (9%)

Query: 11  LGSWSLGDWGAEACTCSPSHPQDAFCNSDIVIRAKVVGKKLVKEGPFGTLVYTIKQMKMY 70
           L +W++ +WG  +          A    D+  R+        K  P GT++ T+ + K Y
Sbjct: 191 LVAWAVSNWGPNSARVRYYQSLQAHLKVDVYGRSH-------KPLPQGTMMETLSRYKFY 243

Query: 71  RGFTKMPHVQYI 82
             F    H  YI
Sbjct: 244 LAFENSLHPDYI 255


>gi|4503815 fucosyltransferase 6 [Homo sapiens]
          Length = 359

 Score = 29.3 bits (64), Expect = 2.6
 Identities = 18/72 (25%), Positives = 29/72 (40%), Gaps = 7/72 (9%)

Query: 11  LGSWSLGDWGAEACTCSPSHPQDAFCNSDIVIRAKVVGKKLVKEGPFGTLVYTIKQMKMY 70
           L +W++ +WG  +          A    D+  R+        K  P GT++ T+ + K Y
Sbjct: 191 LVAWAVSNWGPNSARVRYYQSLQAHLKVDVYGRSH-------KPLPQGTMMETLSRYKFY 243

Query: 71  RGFTKMPHVQYI 82
             F    H  YI
Sbjct: 244 LAFENSLHPDYI 255


>gi|55741659 zinc finger protein 14-like [Homo sapiens]
          Length = 533

 Score = 29.3 bits (64), Expect = 2.6
 Identities = 14/52 (26%), Positives = 27/52 (51%)

Query: 32  QDAFCNSDIVIRAKVVGKKLVKEGPFGTLVYTIKQMKMYRGFTKMPHVQYIH 83
           Q +   +D   ++K+ G+K  +EG FG +  T ++M  Y+    +   Q +H
Sbjct: 115 QGSIFRNDWECKSKIEGEKEQQEGYFGQVKITSEKMTTYKRHNFLTEYQIVH 166


>gi|225703106 tudor domain containing 3 isoform 1 [Homo sapiens]
          Length = 744

 Score = 28.1 bits (61), Expect = 5.7
 Identities = 18/52 (34%), Positives = 25/52 (48%), Gaps = 9/52 (17%)

Query: 6  GLIVLLGSWSLGDWGAEACTCSPSHPQDAFCNSDIVIRA-----KVVGKKLV 52
          G  +    W L D G EACT SP    D    +DI++ A     + +GKK +
Sbjct: 6  GAALSQAGWYLSDEGIEACTSSP----DKVNVNDIILIALNTDLRTIGKKFL 53


>gi|143770880 laminin, beta 4 [Homo sapiens]
          Length = 1761

 Score = 27.3 bits (59), Expect = 9.7
 Identities = 10/26 (38%), Positives = 13/26 (50%)

Query: 12  GSWSLGDWGAEACTCSPSHPQDAFCN 37
           GS+ LG  G   C C P   +D  C+
Sbjct: 805 GSYDLGHHGCHPCHCHPQGSKDTVCD 830


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.323    0.139    0.476 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 8,775,986
Number of Sequences: 37866
Number of extensions: 369672
Number of successful extensions: 776
Number of sequences better than 10.0: 11
Number of HSP's better than 10.0 without gapping: 7
Number of HSP's successfully gapped in prelim test: 4
Number of HSP's that attempted gapping in prelim test: 759
Number of HSP's gapped (non-prelim): 12
length of query: 211
length of database: 18,247,518
effective HSP length: 98
effective length of query: 113
effective length of database: 14,536,650
effective search space: 1642641450
effective search space used: 1642641450
T: 11
A: 40
X1: 16 ( 7.5 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 59 (27.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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