Search of human proteins with 4507511

Search of human proteins with 4507511

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|4507511 TIMP metallopeptidase inhibitor 2 precursor [Homo
sapiens]
         (220 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|4507511 TIMP metallopeptidase inhibitor 2 precursor [Homo sap...   462   e-131
gi|4507515 tissue inhibitor of metalloproteinase 4 precursor [Ho...   227   7e-60
gi|4507513 tissue inhibitor of metalloproteinase 3 precursor [Ho...   197   8e-51
gi|4507509 tissue inhibitor of metalloproteinase 1 precursor [Ho...   159   2e-39
gi|62362414 c-abl oncogene 1, receptor tyrosine kinase isoform a...    30   1.6  
gi|62362412 c-abl oncogene 1, receptor tyrosine kinase isoform b...    30   1.6  
gi|6005772 G protein-coupled receptor 176 [Homo sapiens]               28   4.7  
gi|41349495 DNA primase polypeptide 2 [Homo sapiens]                   28   6.1  

>gi|4507511 TIMP metallopeptidase inhibitor 2 precursor [Homo
           sapiens]
          Length = 220

 Score =  462 bits (1190), Expect = e-131
 Identities = 220/220 (100%), Positives = 220/220 (100%)

Query: 1   MGAAARTLRLALGLLLLATLLRPADACSCSPVHPQQAFCNADVVIRAKAVSEKEVDSGND 60
           MGAAARTLRLALGLLLLATLLRPADACSCSPVHPQQAFCNADVVIRAKAVSEKEVDSGND
Sbjct: 1   MGAAARTLRLALGLLLLATLLRPADACSCSPVHPQQAFCNADVVIRAKAVSEKEVDSGND 60

Query: 61  IYGNPIKRIQYEIKQIKMFKGPEKDIEFIYTAPSSAVCGVSLDVGGKKEYLIAGKAEGDG 120
           IYGNPIKRIQYEIKQIKMFKGPEKDIEFIYTAPSSAVCGVSLDVGGKKEYLIAGKAEGDG
Sbjct: 61  IYGNPIKRIQYEIKQIKMFKGPEKDIEFIYTAPSSAVCGVSLDVGGKKEYLIAGKAEGDG 120

Query: 121 KMHITLCDFIVPWDTLSTTQKKSLNHRYQMGCECKITRCPMIPCYISSPDECLWMDWVTE 180
           KMHITLCDFIVPWDTLSTTQKKSLNHRYQMGCECKITRCPMIPCYISSPDECLWMDWVTE
Sbjct: 121 KMHITLCDFIVPWDTLSTTQKKSLNHRYQMGCECKITRCPMIPCYISSPDECLWMDWVTE 180

Query: 181 KNINGHQAKFFACIKRSDGSCAWYRGAAPPKQEFLDIEDP 220
           KNINGHQAKFFACIKRSDGSCAWYRGAAPPKQEFLDIEDP
Sbjct: 181 KNINGHQAKFFACIKRSDGSCAWYRGAAPPKQEFLDIEDP 220


>gi|4507515 tissue inhibitor of metalloproteinase 4 precursor [Homo
           sapiens]
          Length = 224

 Score =  227 bits (578), Expect = 7e-60
 Identities = 106/212 (50%), Positives = 148/212 (69%), Gaps = 6/212 (2%)

Query: 14  LLLLATLLRP---ADACSCSPVHPQQAFCNADVVIRAKAVSEKEVDSGNDIYGNPIKRIQ 70
           LL L  LLRP    +ACSC+P HPQQ  C++ +VIRAK  SEK V +  D   +  K ++
Sbjct: 14  LLRLLALLRPPGLGEACSCAPAHPQQHICHSALVIRAKISSEKVVPASADP-ADTEKMLR 72

Query: 71  YEIKQIKMFKGPEK--DIEFIYTAPSSAVCGVSLDVGGKKEYLIAGKAEGDGKMHITLCD 128
           YEIKQIKMFKG EK  D+++IYT   S++CGV L+   +K+YL+ G+   DGK+ I LC+
Sbjct: 73  YEIKQIKMFKGFEKVKDVQYIYTPFDSSLCGVKLEANSQKQYLLTGQVLSDGKVFIHLCN 132

Query: 129 FIVPWDTLSTTQKKSLNHRYQMGCECKITRCPMIPCYISSPDECLWMDWVTEKNINGHQA 188
           +I PW+ LS  Q++SLNH Y + C C+IT C  +PC IS+P+ECLW DW+ E+ + G+QA
Sbjct: 133 YIEPWEDLSLVQRESLNHHYHLNCGCQITTCYTVPCTISAPNECLWTDWLLERKLYGYQA 192

Query: 189 KFFACIKRSDGSCAWYRGAAPPKQEFLDIEDP 220
           + + C+K  DG+C+WYRG  P ++EF+DI  P
Sbjct: 193 QHYVCMKHVDGTCSWYRGHLPLRKEFVDIVQP 224


>gi|4507513 tissue inhibitor of metalloproteinase 3 precursor [Homo
           sapiens]
          Length = 211

 Score =  197 bits (500), Expect = 8e-51
 Identities = 90/199 (45%), Positives = 134/199 (67%), Gaps = 10/199 (5%)

Query: 24  ADACSCSPVHPQQAFCNADVVIRAKAVSEKEVDSGNDIYGNPIKRIQYEIKQIKMFKGPE 83
           A+AC+CSP HPQ AFCN+D+VIRAK V +K V  G      P   + Y IKQ+KM++G  
Sbjct: 21  AEACTCSPSHPQDAFCNSDIVIRAKVVGKKLVKEG------PFGTLVYTIKQMKMYRGFT 74

Query: 84  K--DIEFIYTAPSSAVCGVSLDVGGKKEYLIAGKAEGDGKMHITLCDFIVPWDTLSTTQK 141
           K   +++I+T  S ++CG+ L+V  K +YL+ G+   DGKM+  LC+F+  WD L+ +Q+
Sbjct: 75  KMPHVQYIHTEASESLCGLKLEVN-KYQYLLTGRVY-DGKMYTGLCNFVERWDQLTLSQR 132

Query: 142 KSLNHRYQMGCECKITRCPMIPCYISSPDECLWMDWVTEKNINGHQAKFFACIKRSDGSC 201
           K LN+RY +GC CKI  C  +PC+++S +ECLW D ++     G+Q+K +ACI++  G C
Sbjct: 133 KGLNYRYHLGCNCKIKSCYYLPCFVTSKNECLWTDMLSNFGYPGYQSKHYACIRQKGGYC 192

Query: 202 AWYRGAAPPKQEFLDIEDP 220
           +WYRG APP +  ++  DP
Sbjct: 193 SWYRGWAPPDKSIINATDP 211


>gi|4507509 tissue inhibitor of metalloproteinase 1 precursor [Homo
           sapiens]
          Length = 207

 Score =  159 bits (402), Expect = 2e-39
 Identities = 85/201 (42%), Positives = 115/201 (57%), Gaps = 15/201 (7%)

Query: 10  LALGLLLLATLLRPADACSCSPVHPQQAFCNADVVIRAKAVSEKEVDSGNDIYGNPIKRI 69
           LA G+LLL  L+ P+ AC+C P HPQ AFCN+D+VIRAK V   EV+    +Y       
Sbjct: 7   LASGILLLLWLIAPSRACTCVPPHPQTAFCNSDLVIRAKFVGTPEVNQ-TTLYQ------ 59

Query: 70  QYEIKQIKMFK-----GPEKDIEFIYTAPSSAVCG-VSLDVGGKKEYLIAGKAEGDGKMH 123
           +YEIK  KM+K     G   DI F+YT    +VCG         +E+LIAGK + DG +H
Sbjct: 60  RYEIKMTKMYKGFQALGDAADIRFVYTPAMESVCGYFHRSHNRSEEFLIAGKLQ-DGLLH 118

Query: 124 ITLCDFIVPWDTLSTTQKKSLNHRYQMGC-ECKITRCPMIPCYISSPDECLWMDWVTEKN 182
           IT C F+ PW++LS  Q++     Y +GC EC +  C  IPC + S   CLW D + + +
Sbjct: 119 ITTCSFVAPWNSLSLAQRRGFTKTYTVGCEECTVFPCLSIPCKLQSGTHCLWTDQLLQGS 178

Query: 183 INGHQAKFFACIKRSDGSCAW 203
             G Q++  AC+ R  G C W
Sbjct: 179 EKGFQSRHLACLPREPGLCTW 199


>gi|62362414 c-abl oncogene 1, receptor tyrosine kinase isoform a
           [Homo sapiens]
          Length = 1130

 Score = 30.0 bits (66), Expect = 1.6
 Identities = 16/38 (42%), Positives = 23/38 (60%), Gaps = 1/38 (2%)

Query: 108 KEYLIAGKAEGDGKMHITLCDFIVPWD-TLSTTQKKSL 144
           KE L+AG +E D  + + L DF+   D TLS T+ + L
Sbjct: 51  KENLLAGPSENDPNLFVALYDFVASGDNTLSITKGEKL 88


>gi|62362412 c-abl oncogene 1, receptor tyrosine kinase isoform b
           [Homo sapiens]
          Length = 1149

 Score = 30.0 bits (66), Expect = 1.6
 Identities = 16/38 (42%), Positives = 23/38 (60%), Gaps = 1/38 (2%)

Query: 108 KEYLIAGKAEGDGKMHITLCDFIVPWD-TLSTTQKKSL 144
           KE L+AG +E D  + + L DF+   D TLS T+ + L
Sbjct: 70  KENLLAGPSENDPNLFVALYDFVASGDNTLSITKGEKL 107


>gi|6005772 G protein-coupled receptor 176 [Homo sapiens]
          Length = 515

 Score = 28.5 bits (62), Expect = 4.7
 Identities = 17/57 (29%), Positives = 26/57 (45%), Gaps = 6/57 (10%)

Query: 126 LCDFIVPWDTLSTTQKKSLNHRY--QMGCE--CKITRCPMIPCYISSPDECLWMDWV 178
           L +F+V W T  TT  KS+ +R+   + C   C    C      +S+   C W  W+
Sbjct: 57  LGNFMVLWSTCRTTVFKSVTNRFIKNLACSGICASLVCVPFDIILSTSPHCCW--WI 111


>gi|41349495 DNA primase polypeptide 2 [Homo sapiens]
          Length = 509

 Score = 28.1 bits (61), Expect = 6.1
 Identities = 25/91 (27%), Positives = 38/91 (41%), Gaps = 16/91 (17%)

Query: 20  LLRPADACSCSPVHPQQAFCNADVVIRAKAVSEKEVDSGNDIYGNPIKRIQYEIKQIKMF 79
           ++   D C  S  HP Q FC           S++ ++ G DI   P   IQ E  Q K  
Sbjct: 430 MIHNVDDCGFSLNHPNQFFCE----------SQRILNGGKDIKKEP---IQPETPQPKPS 476

Query: 80  KGPEKDIEFIYTAPSSAVCGVSLDVGGKKEY 110
               KD     +A +S    + +D+ G ++Y
Sbjct: 477 VQKTKDAS---SALASLNSSLEMDMEGLEDY 504


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.321    0.137    0.438 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 8,973,148
Number of Sequences: 37866
Number of extensions: 384105
Number of successful extensions: 770
Number of sequences better than 10.0: 8
Number of HSP's better than 10.0 without gapping: 4
Number of HSP's successfully gapped in prelim test: 4
Number of HSP's that attempted gapping in prelim test: 758
Number of HSP's gapped (non-prelim): 9
length of query: 220
length of database: 18,247,518
effective HSP length: 98
effective length of query: 122
effective length of database: 14,536,650
effective search space: 1773471300
effective search space used: 1773471300
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 60 (27.7 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.