Guide to the Human Genome
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Search of human proteins with 4506031

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|4506031 palmitoyl-protein thioesterase 1 isoform 1 precursor
[Homo sapiens]
         (306 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|4506031 palmitoyl-protein thioesterase 1 isoform 1 precursor ...   631   0.0  
gi|217272890 palmitoyl-protein thioesterase 1 isoform 2 precurso...   337   1e-92
gi|18677774 palmitoyl-protein thioesterase 2 isoform a precursor...    79   7e-15
gi|20336251 palmitoyl-protein thioesterase 2 isoform b precursor...    79   7e-15
gi|35493952 ubiquitin protein ligase E3B [Homo sapiens]                32   0.92 
gi|35493959 ubiquitin protein ligase E3B [Homo sapiens]                32   0.92 
gi|30425524 hypothetical protein LOC339669 [Homo sapiens]              30   2.0  
gi|33239440 zinc finger protein, Y-linked isoform 1 [Homo sapiens]     29   4.6  
gi|223717965 zinc finger protein, Y-linked isoform 2 [Homo sapiens]    29   4.6  
gi|5901962 MYST histone acetyltransferase 2 [Homo sapiens]             29   4.6  
gi|83715968 sarcoma antigen NY-SAR-79 [Homo sapiens]                   29   4.6  
gi|34147522 chaperone, ABC1 activity of bc1 complex like precurs...    29   4.6  
gi|55953063 SET domain containing 4 isoform c [Homo sapiens]           29   4.6  
gi|13435127 TRAF3-interacting JNK-activating modulator [Homo sap...    29   4.6  
gi|8393013 SET domain containing 4 isoform a [Homo sapiens]            29   4.6  

>gi|4506031 palmitoyl-protein thioesterase 1 isoform 1 precursor
           [Homo sapiens]
          Length = 306

 Score =  631 bits (1628), Expect = 0.0
 Identities = 306/306 (100%), Positives = 306/306 (100%)

Query: 1   MASPGCLWLLAVALLPWTCASRALQHLDPPAPLPLVIWHGMGDSCCNPLSMGAIKKMVEK 60
           MASPGCLWLLAVALLPWTCASRALQHLDPPAPLPLVIWHGMGDSCCNPLSMGAIKKMVEK
Sbjct: 1   MASPGCLWLLAVALLPWTCASRALQHLDPPAPLPLVIWHGMGDSCCNPLSMGAIKKMVEK 60

Query: 61  KIPGIYVLSLEIGKTLMEDVENSFFLNVNSQVTTVCQALAKDPKLQQGYNAMGFSQGGQF 120
           KIPGIYVLSLEIGKTLMEDVENSFFLNVNSQVTTVCQALAKDPKLQQGYNAMGFSQGGQF
Sbjct: 61  KIPGIYVLSLEIGKTLMEDVENSFFLNVNSQVTTVCQALAKDPKLQQGYNAMGFSQGGQF 120

Query: 121 LRAVAQRCPSPPMINLISVGGQHQGVFGLPRCPGESSHICDFIRKTLNAGAYSKVVQERL 180
           LRAVAQRCPSPPMINLISVGGQHQGVFGLPRCPGESSHICDFIRKTLNAGAYSKVVQERL
Sbjct: 121 LRAVAQRCPSPPMINLISVGGQHQGVFGLPRCPGESSHICDFIRKTLNAGAYSKVVQERL 180

Query: 181 VQAEYWHDPIKEDVYRNHSIFLADINQERGINESYKKNLMALKKFVMVKFLNDSIVDPVD 240
           VQAEYWHDPIKEDVYRNHSIFLADINQERGINESYKKNLMALKKFVMVKFLNDSIVDPVD
Sbjct: 181 VQAEYWHDPIKEDVYRNHSIFLADINQERGINESYKKNLMALKKFVMVKFLNDSIVDPVD 240

Query: 241 SEWFGFYRSGQAKETIPLQETSLYTQDRLGLKEMDNAGQLVFLATEGDHLQLSEEWFYAH 300
           SEWFGFYRSGQAKETIPLQETSLYTQDRLGLKEMDNAGQLVFLATEGDHLQLSEEWFYAH
Sbjct: 241 SEWFGFYRSGQAKETIPLQETSLYTQDRLGLKEMDNAGQLVFLATEGDHLQLSEEWFYAH 300

Query: 301 IIPFLG 306
           IIPFLG
Sbjct: 301 IIPFLG 306


>gi|217272890 palmitoyl-protein thioesterase 1 isoform 2 precursor
           [Homo sapiens]
          Length = 203

 Score =  337 bits (863), Expect = 1e-92
 Identities = 168/185 (90%), Positives = 171/185 (92%), Gaps = 3/185 (1%)

Query: 122 RAVAQRCPSPPMINLISVGGQHQGVFGLPRCPGESSHICDFIRKTLNAGAYSKVVQERLV 181
           RA+    P  P+  +I  G    GVFGLPRCPGESSHICDFIRKTLNAGAYSKVVQERLV
Sbjct: 22  RALQHLDPPAPLPLVIWHG---MGVFGLPRCPGESSHICDFIRKTLNAGAYSKVVQERLV 78

Query: 182 QAEYWHDPIKEDVYRNHSIFLADINQERGINESYKKNLMALKKFVMVKFLNDSIVDPVDS 241
           QAEYWHDPIKEDVYRNHSIFLADINQERGINESYKKNLMALKKFVMVKFLNDSIVDPVDS
Sbjct: 79  QAEYWHDPIKEDVYRNHSIFLADINQERGINESYKKNLMALKKFVMVKFLNDSIVDPVDS 138

Query: 242 EWFGFYRSGQAKETIPLQETSLYTQDRLGLKEMDNAGQLVFLATEGDHLQLSEEWFYAHI 301
           EWFGFYRSGQAKETIPLQETSLYTQDRLGLKEMDNAGQLVFLATEGDHLQLSEEWFYAHI
Sbjct: 139 EWFGFYRSGQAKETIPLQETSLYTQDRLGLKEMDNAGQLVFLATEGDHLQLSEEWFYAHI 198

Query: 302 IPFLG 306
           IPFLG
Sbjct: 199 IPFLG 203



 Score = 97.4 bits (241), Expect = 1e-20
 Identities = 48/77 (62%), Positives = 54/77 (70%), Gaps = 15/77 (19%)

Query: 1  MASPGCLWLLAVALLPWTCASRALQHLDPPAPLPLVIWHGMG---------------DSC 45
          MASPGCLWLLAVALLPWTCASRALQHLDPPAPLPLVIWHGMG               D  
Sbjct: 1  MASPGCLWLLAVALLPWTCASRALQHLDPPAPLPLVIWHGMGVFGLPRCPGESSHICDFI 60

Query: 46 CNPLSMGAIKKMVEKKI 62
             L+ GA  K+V++++
Sbjct: 61 RKTLNAGAYSKVVQERL 77


>gi|18677774 palmitoyl-protein thioesterase 2 isoform a precursor
           [Homo sapiens]
          Length = 302

 Score = 78.6 bits (192), Expect = 7e-15
 Identities = 81/292 (27%), Positives = 131/292 (44%), Gaps = 41/292 (14%)

Query: 4   PGCLWLLAVALLPWTCASRALQHLDPPAP-----LPLVIWHGMGDSCCNPLSMGAIKKMV 58
           P    LL +  LP       L  L  PAP      P+++ HG+ DS     S   + + +
Sbjct: 10  PAAWVLLLLPFLP-------LLLLAAPAPHRASYKPVIVVHGLFDSS---YSFRHLLEYI 59

Query: 59  EKKIPGIYVLSLEI--GKTLMEDVENSFFLNVNSQVTTVCQALAKDPKLQQGYNAMGFSQ 116
            +  PG  V  L++  G+  +  +    +  V      V   +AK P   QG + + +SQ
Sbjct: 60  NETHPGTVVTVLDLFDGRESLRPL----WEQVQGFREAVVPIMAKAP---QGVHLICYSQ 112

Query: 117 GGQFLRAVAQRCPSPPMINLISVGGQHQGVFGLPRCPGESSHIC----DFIRKTLNAGAY 172
           GG   RA+        + + IS+     G +G      ++ ++       +R  L    Y
Sbjct: 113 GGLVCRALLSVMDDHNVDSFISLSSPQMGQYG------DTDYLKWLFPTSMRSNLYRICY 166

Query: 173 SKVVQERLVQAEYWHDPIKEDVYRNHSIFLADINQERGINES--YKKNLMALKKFVMVKF 230
           S   QE  +   YWHDP  +D+Y N S FLA IN ER    +  ++KN + +   V++  
Sbjct: 167 SPWGQEFSI-CNYWHDPHHDDLYLNASSFLALINGERDHPNATVWRKNFLRVGHLVLIGG 225

Query: 231 LNDSIVDPVDSEWFGFYRSGQAKETI-PLQETSLYTQDRLGLKEMDNAGQLV 281
            +D ++ P  S +FGFY    A ET+  ++E  +Y +D  GLK +   G +V
Sbjct: 226 PDDGVITPWQSSFFGFY---DANETVLEMEEQLVYLRDSFGLKTLLARGAIV 274


>gi|20336251 palmitoyl-protein thioesterase 2 isoform b precursor
           [Homo sapiens]
          Length = 308

 Score = 78.6 bits (192), Expect = 7e-15
 Identities = 81/292 (27%), Positives = 131/292 (44%), Gaps = 41/292 (14%)

Query: 4   PGCLWLLAVALLPWTCASRALQHLDPPAP-----LPLVIWHGMGDSCCNPLSMGAIKKMV 58
           P    LL +  LP       L  L  PAP      P+++ HG+ DS     S   + + +
Sbjct: 16  PAAWVLLLLPFLP-------LLLLAAPAPHRASYKPVIVVHGLFDSS---YSFRHLLEYI 65

Query: 59  EKKIPGIYVLSLEI--GKTLMEDVENSFFLNVNSQVTTVCQALAKDPKLQQGYNAMGFSQ 116
            +  PG  V  L++  G+  +  +    +  V      V   +AK P   QG + + +SQ
Sbjct: 66  NETHPGTVVTVLDLFDGRESLRPL----WEQVQGFREAVVPIMAKAP---QGVHLICYSQ 118

Query: 117 GGQFLRAVAQRCPSPPMINLISVGGQHQGVFGLPRCPGESSHIC----DFIRKTLNAGAY 172
           GG   RA+        + + IS+     G +G      ++ ++       +R  L    Y
Sbjct: 119 GGLVCRALLSVMDDHNVDSFISLSSPQMGQYG------DTDYLKWLFPTSMRSNLYRICY 172

Query: 173 SKVVQERLVQAEYWHDPIKEDVYRNHSIFLADINQERGINES--YKKNLMALKKFVMVKF 230
           S   QE  +   YWHDP  +D+Y N S FLA IN ER    +  ++KN + +   V++  
Sbjct: 173 SPWGQEFSI-CNYWHDPHHDDLYLNASSFLALINGERDHPNATVWRKNFLRVGHLVLIGG 231

Query: 231 LNDSIVDPVDSEWFGFYRSGQAKETI-PLQETSLYTQDRLGLKEMDNAGQLV 281
            +D ++ P  S +FGFY    A ET+  ++E  +Y +D  GLK +   G +V
Sbjct: 232 PDDGVITPWQSSFFGFY---DANETVLEMEEQLVYLRDSFGLKTLLARGAIV 280


>gi|35493952 ubiquitin protein ligase E3B [Homo sapiens]
          Length = 1068

 Score = 31.6 bits (70), Expect = 0.92
 Identities = 24/123 (19%), Positives = 55/123 (44%), Gaps = 10/123 (8%)

Query: 108 GYNAMGFSQGG---QFLRAVAQRCPSPPMINLISVGGQHQGVFGLPRCPGESSHI--CDF 162
           G +  G  Q G   +FL  + +R    P +NL       + ++  P      +++   +F
Sbjct: 719 GVDEAGIDQDGVFKEFLEEIIKRV-FDPALNLFKTTSGDERLYPSPTSYIHENYLQLFEF 777

Query: 163 IRKTLNAGAYSKVVQERLVQAEYWHDPIKEDVYRNHSIFLADINQERGINESYKKNLMAL 222
           + K L    Y  +V    V   +    + + +  +HS+F + +++   ++  + KNL ++
Sbjct: 778 VGKMLGKAVYEGIV----VDVPFASFFLSQLLGHHHSVFYSSVDELPSLDSEFYKNLTSI 833

Query: 223 KKF 225
           K++
Sbjct: 834 KRY 836


>gi|35493959 ubiquitin protein ligase E3B [Homo sapiens]
          Length = 1068

 Score = 31.6 bits (70), Expect = 0.92
 Identities = 24/123 (19%), Positives = 55/123 (44%), Gaps = 10/123 (8%)

Query: 108 GYNAMGFSQGG---QFLRAVAQRCPSPPMINLISVGGQHQGVFGLPRCPGESSHI--CDF 162
           G +  G  Q G   +FL  + +R    P +NL       + ++  P      +++   +F
Sbjct: 719 GVDEAGIDQDGVFKEFLEEIIKRV-FDPALNLFKTTSGDERLYPSPTSYIHENYLQLFEF 777

Query: 163 IRKTLNAGAYSKVVQERLVQAEYWHDPIKEDVYRNHSIFLADINQERGINESYKKNLMAL 222
           + K L    Y  +V    V   +    + + +  +HS+F + +++   ++  + KNL ++
Sbjct: 778 VGKMLGKAVYEGIV----VDVPFASFFLSQLLGHHHSVFYSSVDELPSLDSEFYKNLTSI 833

Query: 223 KKF 225
           K++
Sbjct: 834 KRY 836


>gi|30425524 hypothetical protein LOC339669 [Homo sapiens]
          Length = 195

 Score = 30.4 bits (67), Expect = 2.0
 Identities = 16/55 (29%), Positives = 30/55 (54%), Gaps = 1/55 (1%)

Query: 165 KTLNAGAYSKVVQERLVQ-AEYWHDPIKEDVYRNHSIFLADINQERGINESYKKN 218
           K+L   +Y+  V E+ V+  E+WH    +D+ R H     ++N ++ + E Y +N
Sbjct: 133 KSLMKASYTPEVIEKSVRDLEHWHGRKTDDLGRWHQKNAMNLNLQKALEEKYGEN 187


>gi|33239440 zinc finger protein, Y-linked isoform 1 [Homo sapiens]
          Length = 801

 Score = 29.3 bits (64), Expect = 4.6
 Identities = 18/60 (30%), Positives = 29/60 (48%), Gaps = 8/60 (13%)

Query: 155 ESSHICDFIRKTLNAGAYSKVVQERLVQAEYWHDPIKEDVYRNHSIFLADINQERGINES 214
           ES H+CD        G    +V + +V+AE   DP+  D+  +  + +AD   E  I+ S
Sbjct: 139 ESMHVCDI-------GHVEHMVHDSVVEAEIITDPLTSDIV-SEEVLVADCAPEAVIDAS 190


>gi|223717965 zinc finger protein, Y-linked isoform 2 [Homo sapiens]
          Length = 724

 Score = 29.3 bits (64), Expect = 4.6
 Identities = 18/60 (30%), Positives = 29/60 (48%), Gaps = 8/60 (13%)

Query: 155 ESSHICDFIRKTLNAGAYSKVVQERLVQAEYWHDPIKEDVYRNHSIFLADINQERGINES 214
           ES H+CD        G    +V + +V+AE   DP+  D+  +  + +AD   E  I+ S
Sbjct: 113 ESMHVCDI-------GHVEHMVHDSVVEAEIITDPLTSDIV-SEEVLVADCAPEAVIDAS 164


>gi|5901962 MYST histone acetyltransferase 2 [Homo sapiens]
          Length = 611

 Score = 29.3 bits (64), Expect = 4.6
 Identities = 30/150 (20%), Positives = 64/150 (42%), Gaps = 14/150 (9%)

Query: 127 RCPSPPMINLISVGGQHQGVFGLPRCPGESSHICDFIRKTLNAGAYSKVVQERLVQAEYW 186
           +CP+P   +L  + G+H+  F +  CP   +   D  +  + A +  K ++ER++   + 
Sbjct: 184 KCPTPGCNSLGHLTGKHERHFSISGCPLYHNLSADECK--VRAQSRDKQIEERML--SHR 239

Query: 187 HDPIKEDVYRNHSIFLADINQERGINESYKKNLMALKKFVMVKFL---------NDSIVD 237
            D       R+ +     +  +  + E  KK    L K    K++          + +++
Sbjct: 240 QDDNNRHATRHQAPTERQLRYKEKVAELRKKRNSGLSKEQKEKYMEHRQTYGNTREPLLE 299

Query: 238 PVDSEW-FGFYRSGQAKETIPLQETSLYTQ 266
            + SE+    +R  QA+ +  L++  L  Q
Sbjct: 300 NLTSEYDLDLFRRAQARASEDLEKLRLQGQ 329


>gi|83715968 sarcoma antigen NY-SAR-79 [Homo sapiens]
          Length = 1079

 Score = 29.3 bits (64), Expect = 4.6
 Identities = 21/50 (42%), Positives = 28/50 (56%), Gaps = 2/50 (4%)

Query: 253 KETIPLQETSLYTQDRLGLKEMDNAGQLVFLATEGDHLQLSE-EWFYAHI 301
           KET+   + S Y+  +  + EM+   QL  LA E  H QLSE E +YA I
Sbjct: 123 KETLKALQVSKYSLQKK-VSEMEQKVQLHLLAKEDYHKQLSEIEKYYATI 171


>gi|34147522 chaperone, ABC1 activity of bc1 complex like precursor
           [Homo sapiens]
          Length = 647

 Score = 29.3 bits (64), Expect = 4.6
 Identities = 27/104 (25%), Positives = 48/104 (46%), Gaps = 6/104 (5%)

Query: 167 LNAGAYSKVVQERLVQAEYWHDPIKEDVYRNHSIFLADINQERGINESYKKNLMALKKFV 226
           L  GA ++V ++ L       DP  +      S FL++ N ER +    K    ALK   
Sbjct: 224 LGFGALAEVAKKSLRS----EDPSGKKAVLGSSPFLSEANAERIVRTLCKVRGAALKLGQ 279

Query: 227 MVKFLNDSIVDPVDSEWFGFYRSGQAKETIPLQETSLYTQDRLG 270
           M+   +D+ ++P  ++   F R  Q+ + +PL++      + LG
Sbjct: 280 MLSIQDDAFINPHLAKI--FERVRQSADFMPLKQMMKTLNNDLG 321


>gi|55953063 SET domain containing 4 isoform c [Homo sapiens]
          Length = 307

 Score = 29.3 bits (64), Expect = 4.6
 Identities = 12/37 (32%), Positives = 22/37 (59%)

Query: 202 LADINQERGINESYKKNLMALKKFVMVKFLNDSIVDP 238
           L   ++ RG+NES+K   + L+K++  +   DS + P
Sbjct: 16  LCGSSESRGVNESHKSEFIELRKWLKARKFQDSNLAP 52


>gi|13435127 TRAF3-interacting JNK-activating modulator [Homo
           sapiens]
          Length = 531

 Score = 29.3 bits (64), Expect = 4.6
 Identities = 14/55 (25%), Positives = 28/55 (50%)

Query: 211 INESYKKNLMALKKFVMVKFLNDSIVDPVDSEWFGFYRSGQAKETIPLQETSLYT 265
           + E+ ++ L+  +K V+++ L  +++   DS W G     + K  +   E  LYT
Sbjct: 181 LKEALQRELVLKQKMVILQDLLSTLIQASDSSWKGQLNEDKLKGKLRSLENQLYT 235


>gi|8393013 SET domain containing 4 isoform a [Homo sapiens]
          Length = 440

 Score = 29.3 bits (64), Expect = 4.6
 Identities = 12/37 (32%), Positives = 22/37 (59%)

Query: 202 LADINQERGINESYKKNLMALKKFVMVKFLNDSIVDP 238
           L   ++ RG+NES+K   + L+K++  +   DS + P
Sbjct: 16  LCGSSESRGVNESHKSEFIELRKWLKARKFQDSNLAP 52


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.321    0.137    0.429 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 11,770,208
Number of Sequences: 37866
Number of extensions: 507281
Number of successful extensions: 1167
Number of sequences better than 10.0: 15
Number of HSP's better than 10.0 without gapping: 8
Number of HSP's successfully gapped in prelim test: 7
Number of HSP's that attempted gapping in prelim test: 1154
Number of HSP's gapped (non-prelim): 18
length of query: 306
length of database: 18,247,518
effective HSP length: 102
effective length of query: 204
effective length of database: 14,385,186
effective search space: 2934577944
effective search space used: 2934577944
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 62 (28.5 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
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