Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Search of human proteins with 4505601
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4505601 p21-activated kinase 3 isoform a [Homo sapiens]
(544 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|189491753 p21-activated kinase 3 isoform a [Homo sapiens] 1087 0.0
gi|189491751 p21-activated kinase 3 isoform a [Homo sapiens] 1087 0.0
gi|4505601 p21-activated kinase 3 isoform a [Homo sapiens] 1087 0.0
gi|189491759 p21-activated kinase 3 isoform d [Homo sapiens] 1077 0.0
gi|189491757 p21-activated kinase 3 isoform c [Homo sapiens] 1075 0.0
gi|189491755 p21-activated kinase 3 isoform b [Homo sapiens] 1069 0.0
gi|42794769 p21-activated kinase 1 isoform 2 [Homo sapiens] 872 0.0
gi|190886457 p21-activated kinase 1 isoform 1 [Homo sapiens] 830 0.0
gi|32483399 p21-activated kinase 2 [Homo sapiens] 793 0.0
gi|62422561 p21-activated kinase 4 isoform 2 [Homo sapiens] 359 3e-99
gi|62422563 p21-activated kinase 4 isoform 2 [Homo sapiens] 359 3e-99
gi|62422554 p21-activated kinase 4 isoform 1 [Homo sapiens] 319 4e-87
gi|62422557 p21-activated kinase 4 isoform 1 [Homo sapiens] 319 4e-87
gi|5031975 p21-activated kinase 4 isoform 1 [Homo sapiens] 319 4e-87
gi|29826329 p21-activated kinase 7 [Homo sapiens] 316 4e-86
gi|24308191 p21-activated kinase 7 [Homo sapiens] 316 4e-86
gi|191252782 p21-activated kinase 6 [Homo sapiens] 302 5e-82
gi|191252780 p21-activated kinase 6 [Homo sapiens] 302 5e-82
gi|9910476 p21-activated kinase 6 [Homo sapiens] 302 5e-82
gi|103471999 serine/threonine kinase 3 [Homo sapiens] 244 1e-64
gi|5454096 serine/threonine kinase 4 [Homo sapiens] 244 1e-64
gi|15011880 serine/threonine protein kinase MST4 isoform 1 [Homo... 239 4e-63
gi|110349738 serine/threonine kinase 24 isoform b [Homo sapiens] 238 8e-63
gi|20070158 serine/threonine kinase 24 isoform a [Homo sapiens] 238 8e-63
gi|21361358 serine/threonine kinase 25 [Homo sapiens] 236 4e-62
gi|22035600 mitogen-activated protein kinase kinase kinase kinas... 214 2e-55
gi|41281453 serine/threonine kinase 2 [Homo sapiens] 213 5e-55
gi|15451902 mitogen-activated protein kinase kinase kinase kinas... 206 3e-53
gi|145275208 myosin IIIA [Homo sapiens] 203 3e-52
gi|45439370 TAO kinase 1 [Homo sapiens] 202 5e-52
>gi|189491753 p21-activated kinase 3 isoform a [Homo sapiens]
Length = 544
Score = 1087 bits (2811), Expect = 0.0
Identities = 544/544 (100%), Positives = 544/544 (100%)
Query: 1 MSDGLDNEEKPPAPPLRMNSNNRDSSALNHSSKPLPMAPEEKNKKARLRSIFPGGGDKTN 60
MSDGLDNEEKPPAPPLRMNSNNRDSSALNHSSKPLPMAPEEKNKKARLRSIFPGGGDKTN
Sbjct: 1 MSDGLDNEEKPPAPPLRMNSNNRDSSALNHSSKPLPMAPEEKNKKARLRSIFPGGGDKTN 60
Query: 61 KKKEKERPEISLPSDFEHTIHVGFDAVTGEFTGIPEQWARLLQTSNITKLEQKKNPQAVL 120
KKKEKERPEISLPSDFEHTIHVGFDAVTGEFTGIPEQWARLLQTSNITKLEQKKNPQAVL
Sbjct: 61 KKKEKERPEISLPSDFEHTIHVGFDAVTGEFTGIPEQWARLLQTSNITKLEQKKNPQAVL 120
Query: 121 DVLKFYDSKETVNNQKYMSFTSGDKSAHGYIAAHPSSTKTASEPPLAPPVSEEEDEEEEE 180
DVLKFYDSKETVNNQKYMSFTSGDKSAHGYIAAHPSSTKTASEPPLAPPVSEEEDEEEEE
Sbjct: 121 DVLKFYDSKETVNNQKYMSFTSGDKSAHGYIAAHPSSTKTASEPPLAPPVSEEEDEEEEE 180
Query: 181 EEDENEPPPVIAPRPEHTKSIYTRSVVESIASPAVPNKEVTPPSAENANSSTLYRNTDRQ 240
EEDENEPPPVIAPRPEHTKSIYTRSVVESIASPAVPNKEVTPPSAENANSSTLYRNTDRQ
Sbjct: 181 EEDENEPPPVIAPRPEHTKSIYTRSVVESIASPAVPNKEVTPPSAENANSSTLYRNTDRQ 240
Query: 241 RKKSKMTDEEILEKLRSIVSVGDPKKKYTRFEKIGQGASGTVYTALDIATGQEVAIKQMN 300
RKKSKMTDEEILEKLRSIVSVGDPKKKYTRFEKIGQGASGTVYTALDIATGQEVAIKQMN
Sbjct: 241 RKKSKMTDEEILEKLRSIVSVGDPKKKYTRFEKIGQGASGTVYTALDIATGQEVAIKQMN 300
Query: 301 LQQQPKKELIINEILVMRENKNPNIVNYLDSYLVGDELWVVMEYLAGGSLTDVVTETCMD 360
LQQQPKKELIINEILVMRENKNPNIVNYLDSYLVGDELWVVMEYLAGGSLTDVVTETCMD
Sbjct: 301 LQQQPKKELIINEILVMRENKNPNIVNYLDSYLVGDELWVVMEYLAGGSLTDVVTETCMD 360
Query: 361 EGQIAAVCRECLQALDFLHSNQVIHRDIKSDNILLGMDGSVKLTDFGFCAQITPEQSKRS 420
EGQIAAVCRECLQALDFLHSNQVIHRDIKSDNILLGMDGSVKLTDFGFCAQITPEQSKRS
Sbjct: 361 EGQIAAVCRECLQALDFLHSNQVIHRDIKSDNILLGMDGSVKLTDFGFCAQITPEQSKRS 420
Query: 421 TMVGTPYWMAPEVVTRKAYGPKVDIWSLGIMAIEMVEGEPPYLNENPLRALYLIATNGTP 480
TMVGTPYWMAPEVVTRKAYGPKVDIWSLGIMAIEMVEGEPPYLNENPLRALYLIATNGTP
Sbjct: 421 TMVGTPYWMAPEVVTRKAYGPKVDIWSLGIMAIEMVEGEPPYLNENPLRALYLIATNGTP 480
Query: 481 ELQNPERLSAVFRDFLNRCLEMDVDRRGSAKELLQHPFLKLAKPLSSLTPLIIAAKEAIK 540
ELQNPERLSAVFRDFLNRCLEMDVDRRGSAKELLQHPFLKLAKPLSSLTPLIIAAKEAIK
Sbjct: 481 ELQNPERLSAVFRDFLNRCLEMDVDRRGSAKELLQHPFLKLAKPLSSLTPLIIAAKEAIK 540
Query: 541 NSSR 544
NSSR
Sbjct: 541 NSSR 544
>gi|189491751 p21-activated kinase 3 isoform a [Homo sapiens]
Length = 544
Score = 1087 bits (2811), Expect = 0.0
Identities = 544/544 (100%), Positives = 544/544 (100%)
Query: 1 MSDGLDNEEKPPAPPLRMNSNNRDSSALNHSSKPLPMAPEEKNKKARLRSIFPGGGDKTN 60
MSDGLDNEEKPPAPPLRMNSNNRDSSALNHSSKPLPMAPEEKNKKARLRSIFPGGGDKTN
Sbjct: 1 MSDGLDNEEKPPAPPLRMNSNNRDSSALNHSSKPLPMAPEEKNKKARLRSIFPGGGDKTN 60
Query: 61 KKKEKERPEISLPSDFEHTIHVGFDAVTGEFTGIPEQWARLLQTSNITKLEQKKNPQAVL 120
KKKEKERPEISLPSDFEHTIHVGFDAVTGEFTGIPEQWARLLQTSNITKLEQKKNPQAVL
Sbjct: 61 KKKEKERPEISLPSDFEHTIHVGFDAVTGEFTGIPEQWARLLQTSNITKLEQKKNPQAVL 120
Query: 121 DVLKFYDSKETVNNQKYMSFTSGDKSAHGYIAAHPSSTKTASEPPLAPPVSEEEDEEEEE 180
DVLKFYDSKETVNNQKYMSFTSGDKSAHGYIAAHPSSTKTASEPPLAPPVSEEEDEEEEE
Sbjct: 121 DVLKFYDSKETVNNQKYMSFTSGDKSAHGYIAAHPSSTKTASEPPLAPPVSEEEDEEEEE 180
Query: 181 EEDENEPPPVIAPRPEHTKSIYTRSVVESIASPAVPNKEVTPPSAENANSSTLYRNTDRQ 240
EEDENEPPPVIAPRPEHTKSIYTRSVVESIASPAVPNKEVTPPSAENANSSTLYRNTDRQ
Sbjct: 181 EEDENEPPPVIAPRPEHTKSIYTRSVVESIASPAVPNKEVTPPSAENANSSTLYRNTDRQ 240
Query: 241 RKKSKMTDEEILEKLRSIVSVGDPKKKYTRFEKIGQGASGTVYTALDIATGQEVAIKQMN 300
RKKSKMTDEEILEKLRSIVSVGDPKKKYTRFEKIGQGASGTVYTALDIATGQEVAIKQMN
Sbjct: 241 RKKSKMTDEEILEKLRSIVSVGDPKKKYTRFEKIGQGASGTVYTALDIATGQEVAIKQMN 300
Query: 301 LQQQPKKELIINEILVMRENKNPNIVNYLDSYLVGDELWVVMEYLAGGSLTDVVTETCMD 360
LQQQPKKELIINEILVMRENKNPNIVNYLDSYLVGDELWVVMEYLAGGSLTDVVTETCMD
Sbjct: 301 LQQQPKKELIINEILVMRENKNPNIVNYLDSYLVGDELWVVMEYLAGGSLTDVVTETCMD 360
Query: 361 EGQIAAVCRECLQALDFLHSNQVIHRDIKSDNILLGMDGSVKLTDFGFCAQITPEQSKRS 420
EGQIAAVCRECLQALDFLHSNQVIHRDIKSDNILLGMDGSVKLTDFGFCAQITPEQSKRS
Sbjct: 361 EGQIAAVCRECLQALDFLHSNQVIHRDIKSDNILLGMDGSVKLTDFGFCAQITPEQSKRS 420
Query: 421 TMVGTPYWMAPEVVTRKAYGPKVDIWSLGIMAIEMVEGEPPYLNENPLRALYLIATNGTP 480
TMVGTPYWMAPEVVTRKAYGPKVDIWSLGIMAIEMVEGEPPYLNENPLRALYLIATNGTP
Sbjct: 421 TMVGTPYWMAPEVVTRKAYGPKVDIWSLGIMAIEMVEGEPPYLNENPLRALYLIATNGTP 480
Query: 481 ELQNPERLSAVFRDFLNRCLEMDVDRRGSAKELLQHPFLKLAKPLSSLTPLIIAAKEAIK 540
ELQNPERLSAVFRDFLNRCLEMDVDRRGSAKELLQHPFLKLAKPLSSLTPLIIAAKEAIK
Sbjct: 481 ELQNPERLSAVFRDFLNRCLEMDVDRRGSAKELLQHPFLKLAKPLSSLTPLIIAAKEAIK 540
Query: 541 NSSR 544
NSSR
Sbjct: 541 NSSR 544
>gi|4505601 p21-activated kinase 3 isoform a [Homo sapiens]
Length = 544
Score = 1087 bits (2811), Expect = 0.0
Identities = 544/544 (100%), Positives = 544/544 (100%)
Query: 1 MSDGLDNEEKPPAPPLRMNSNNRDSSALNHSSKPLPMAPEEKNKKARLRSIFPGGGDKTN 60
MSDGLDNEEKPPAPPLRMNSNNRDSSALNHSSKPLPMAPEEKNKKARLRSIFPGGGDKTN
Sbjct: 1 MSDGLDNEEKPPAPPLRMNSNNRDSSALNHSSKPLPMAPEEKNKKARLRSIFPGGGDKTN 60
Query: 61 KKKEKERPEISLPSDFEHTIHVGFDAVTGEFTGIPEQWARLLQTSNITKLEQKKNPQAVL 120
KKKEKERPEISLPSDFEHTIHVGFDAVTGEFTGIPEQWARLLQTSNITKLEQKKNPQAVL
Sbjct: 61 KKKEKERPEISLPSDFEHTIHVGFDAVTGEFTGIPEQWARLLQTSNITKLEQKKNPQAVL 120
Query: 121 DVLKFYDSKETVNNQKYMSFTSGDKSAHGYIAAHPSSTKTASEPPLAPPVSEEEDEEEEE 180
DVLKFYDSKETVNNQKYMSFTSGDKSAHGYIAAHPSSTKTASEPPLAPPVSEEEDEEEEE
Sbjct: 121 DVLKFYDSKETVNNQKYMSFTSGDKSAHGYIAAHPSSTKTASEPPLAPPVSEEEDEEEEE 180
Query: 181 EEDENEPPPVIAPRPEHTKSIYTRSVVESIASPAVPNKEVTPPSAENANSSTLYRNTDRQ 240
EEDENEPPPVIAPRPEHTKSIYTRSVVESIASPAVPNKEVTPPSAENANSSTLYRNTDRQ
Sbjct: 181 EEDENEPPPVIAPRPEHTKSIYTRSVVESIASPAVPNKEVTPPSAENANSSTLYRNTDRQ 240
Query: 241 RKKSKMTDEEILEKLRSIVSVGDPKKKYTRFEKIGQGASGTVYTALDIATGQEVAIKQMN 300
RKKSKMTDEEILEKLRSIVSVGDPKKKYTRFEKIGQGASGTVYTALDIATGQEVAIKQMN
Sbjct: 241 RKKSKMTDEEILEKLRSIVSVGDPKKKYTRFEKIGQGASGTVYTALDIATGQEVAIKQMN 300
Query: 301 LQQQPKKELIINEILVMRENKNPNIVNYLDSYLVGDELWVVMEYLAGGSLTDVVTETCMD 360
LQQQPKKELIINEILVMRENKNPNIVNYLDSYLVGDELWVVMEYLAGGSLTDVVTETCMD
Sbjct: 301 LQQQPKKELIINEILVMRENKNPNIVNYLDSYLVGDELWVVMEYLAGGSLTDVVTETCMD 360
Query: 361 EGQIAAVCRECLQALDFLHSNQVIHRDIKSDNILLGMDGSVKLTDFGFCAQITPEQSKRS 420
EGQIAAVCRECLQALDFLHSNQVIHRDIKSDNILLGMDGSVKLTDFGFCAQITPEQSKRS
Sbjct: 361 EGQIAAVCRECLQALDFLHSNQVIHRDIKSDNILLGMDGSVKLTDFGFCAQITPEQSKRS 420
Query: 421 TMVGTPYWMAPEVVTRKAYGPKVDIWSLGIMAIEMVEGEPPYLNENPLRALYLIATNGTP 480
TMVGTPYWMAPEVVTRKAYGPKVDIWSLGIMAIEMVEGEPPYLNENPLRALYLIATNGTP
Sbjct: 421 TMVGTPYWMAPEVVTRKAYGPKVDIWSLGIMAIEMVEGEPPYLNENPLRALYLIATNGTP 480
Query: 481 ELQNPERLSAVFRDFLNRCLEMDVDRRGSAKELLQHPFLKLAKPLSSLTPLIIAAKEAIK 540
ELQNPERLSAVFRDFLNRCLEMDVDRRGSAKELLQHPFLKLAKPLSSLTPLIIAAKEAIK
Sbjct: 481 ELQNPERLSAVFRDFLNRCLEMDVDRRGSAKELLQHPFLKLAKPLSSLTPLIIAAKEAIK 540
Query: 541 NSSR 544
NSSR
Sbjct: 541 NSSR 544
>gi|189491759 p21-activated kinase 3 isoform d [Homo sapiens]
Length = 559
Score = 1077 bits (2785), Expect = 0.0
Identities = 544/559 (97%), Positives = 544/559 (97%), Gaps = 15/559 (2%)
Query: 1 MSDGLDNEEKPPAPPLRMNSNNRDSSALNHSSKPLPMAPEEKNKKARLRSIFPGGGDKTN 60
MSDGLDNEEKPPAPPLRMNSNNRDSSALNHSSKPLPMAPEEKNKKARLRSIFPGGGDKTN
Sbjct: 1 MSDGLDNEEKPPAPPLRMNSNNRDSSALNHSSKPLPMAPEEKNKKARLRSIFPGGGDKTN 60
Query: 61 KKKEKERPEISLPSDFEHTIHVGFDAVTGEFT---------------GIPEQWARLLQTS 105
KKKEKERPEISLPSDFEHTIHVGFDAVTGEFT GIPEQWARLLQTS
Sbjct: 61 KKKEKERPEISLPSDFEHTIHVGFDAVTGEFTPDLYGSQMCPGKLPEGIPEQWARLLQTS 120
Query: 106 NITKLEQKKNPQAVLDVLKFYDSKETVNNQKYMSFTSGDKSAHGYIAAHPSSTKTASEPP 165
NITKLEQKKNPQAVLDVLKFYDSKETVNNQKYMSFTSGDKSAHGYIAAHPSSTKTASEPP
Sbjct: 121 NITKLEQKKNPQAVLDVLKFYDSKETVNNQKYMSFTSGDKSAHGYIAAHPSSTKTASEPP 180
Query: 166 LAPPVSEEEDEEEEEEEDENEPPPVIAPRPEHTKSIYTRSVVESIASPAVPNKEVTPPSA 225
LAPPVSEEEDEEEEEEEDENEPPPVIAPRPEHTKSIYTRSVVESIASPAVPNKEVTPPSA
Sbjct: 181 LAPPVSEEEDEEEEEEEDENEPPPVIAPRPEHTKSIYTRSVVESIASPAVPNKEVTPPSA 240
Query: 226 ENANSSTLYRNTDRQRKKSKMTDEEILEKLRSIVSVGDPKKKYTRFEKIGQGASGTVYTA 285
ENANSSTLYRNTDRQRKKSKMTDEEILEKLRSIVSVGDPKKKYTRFEKIGQGASGTVYTA
Sbjct: 241 ENANSSTLYRNTDRQRKKSKMTDEEILEKLRSIVSVGDPKKKYTRFEKIGQGASGTVYTA 300
Query: 286 LDIATGQEVAIKQMNLQQQPKKELIINEILVMRENKNPNIVNYLDSYLVGDELWVVMEYL 345
LDIATGQEVAIKQMNLQQQPKKELIINEILVMRENKNPNIVNYLDSYLVGDELWVVMEYL
Sbjct: 301 LDIATGQEVAIKQMNLQQQPKKELIINEILVMRENKNPNIVNYLDSYLVGDELWVVMEYL 360
Query: 346 AGGSLTDVVTETCMDEGQIAAVCRECLQALDFLHSNQVIHRDIKSDNILLGMDGSVKLTD 405
AGGSLTDVVTETCMDEGQIAAVCRECLQALDFLHSNQVIHRDIKSDNILLGMDGSVKLTD
Sbjct: 361 AGGSLTDVVTETCMDEGQIAAVCRECLQALDFLHSNQVIHRDIKSDNILLGMDGSVKLTD 420
Query: 406 FGFCAQITPEQSKRSTMVGTPYWMAPEVVTRKAYGPKVDIWSLGIMAIEMVEGEPPYLNE 465
FGFCAQITPEQSKRSTMVGTPYWMAPEVVTRKAYGPKVDIWSLGIMAIEMVEGEPPYLNE
Sbjct: 421 FGFCAQITPEQSKRSTMVGTPYWMAPEVVTRKAYGPKVDIWSLGIMAIEMVEGEPPYLNE 480
Query: 466 NPLRALYLIATNGTPELQNPERLSAVFRDFLNRCLEMDVDRRGSAKELLQHPFLKLAKPL 525
NPLRALYLIATNGTPELQNPERLSAVFRDFLNRCLEMDVDRRGSAKELLQHPFLKLAKPL
Sbjct: 481 NPLRALYLIATNGTPELQNPERLSAVFRDFLNRCLEMDVDRRGSAKELLQHPFLKLAKPL 540
Query: 526 SSLTPLIIAAKEAIKNSSR 544
SSLTPLIIAAKEAIKNSSR
Sbjct: 541 SSLTPLIIAAKEAIKNSSR 559
>gi|189491757 p21-activated kinase 3 isoform c [Homo sapiens]
Length = 565
Score = 1075 bits (2779), Expect = 0.0
Identities = 544/565 (96%), Positives = 544/565 (96%), Gaps = 21/565 (3%)
Query: 1 MSDGLDNEEKPPAPPLRMNSNNRDSSALNHSSKPLPMAPEEKNKKARLRSIFPGGGDKTN 60
MSDGLDNEEKPPAPPLRMNSNNRDSSALNHSSKPLPMAPEEKNKKARLRSIFPGGGDKTN
Sbjct: 1 MSDGLDNEEKPPAPPLRMNSNNRDSSALNHSSKPLPMAPEEKNKKARLRSIFPGGGDKTN 60
Query: 61 KKKEKERPEISLPSDFEHTIHVGFDAVTGEFT---------------------GIPEQWA 99
KKKEKERPEISLPSDFEHTIHVGFDAVTGEFT GIPEQWA
Sbjct: 61 KKKEKERPEISLPSDFEHTIHVGFDAVTGEFTNSPFQTSRPVTVASSQSEGKMGIPEQWA 120
Query: 100 RLLQTSNITKLEQKKNPQAVLDVLKFYDSKETVNNQKYMSFTSGDKSAHGYIAAHPSSTK 159
RLLQTSNITKLEQKKNPQAVLDVLKFYDSKETVNNQKYMSFTSGDKSAHGYIAAHPSSTK
Sbjct: 121 RLLQTSNITKLEQKKNPQAVLDVLKFYDSKETVNNQKYMSFTSGDKSAHGYIAAHPSSTK 180
Query: 160 TASEPPLAPPVSEEEDEEEEEEEDENEPPPVIAPRPEHTKSIYTRSVVESIASPAVPNKE 219
TASEPPLAPPVSEEEDEEEEEEEDENEPPPVIAPRPEHTKSIYTRSVVESIASPAVPNKE
Sbjct: 181 TASEPPLAPPVSEEEDEEEEEEEDENEPPPVIAPRPEHTKSIYTRSVVESIASPAVPNKE 240
Query: 220 VTPPSAENANSSTLYRNTDRQRKKSKMTDEEILEKLRSIVSVGDPKKKYTRFEKIGQGAS 279
VTPPSAENANSSTLYRNTDRQRKKSKMTDEEILEKLRSIVSVGDPKKKYTRFEKIGQGAS
Sbjct: 241 VTPPSAENANSSTLYRNTDRQRKKSKMTDEEILEKLRSIVSVGDPKKKYTRFEKIGQGAS 300
Query: 280 GTVYTALDIATGQEVAIKQMNLQQQPKKELIINEILVMRENKNPNIVNYLDSYLVGDELW 339
GTVYTALDIATGQEVAIKQMNLQQQPKKELIINEILVMRENKNPNIVNYLDSYLVGDELW
Sbjct: 301 GTVYTALDIATGQEVAIKQMNLQQQPKKELIINEILVMRENKNPNIVNYLDSYLVGDELW 360
Query: 340 VVMEYLAGGSLTDVVTETCMDEGQIAAVCRECLQALDFLHSNQVIHRDIKSDNILLGMDG 399
VVMEYLAGGSLTDVVTETCMDEGQIAAVCRECLQALDFLHSNQVIHRDIKSDNILLGMDG
Sbjct: 361 VVMEYLAGGSLTDVVTETCMDEGQIAAVCRECLQALDFLHSNQVIHRDIKSDNILLGMDG 420
Query: 400 SVKLTDFGFCAQITPEQSKRSTMVGTPYWMAPEVVTRKAYGPKVDIWSLGIMAIEMVEGE 459
SVKLTDFGFCAQITPEQSKRSTMVGTPYWMAPEVVTRKAYGPKVDIWSLGIMAIEMVEGE
Sbjct: 421 SVKLTDFGFCAQITPEQSKRSTMVGTPYWMAPEVVTRKAYGPKVDIWSLGIMAIEMVEGE 480
Query: 460 PPYLNENPLRALYLIATNGTPELQNPERLSAVFRDFLNRCLEMDVDRRGSAKELLQHPFL 519
PPYLNENPLRALYLIATNGTPELQNPERLSAVFRDFLNRCLEMDVDRRGSAKELLQHPFL
Sbjct: 481 PPYLNENPLRALYLIATNGTPELQNPERLSAVFRDFLNRCLEMDVDRRGSAKELLQHPFL 540
Query: 520 KLAKPLSSLTPLIIAAKEAIKNSSR 544
KLAKPLSSLTPLIIAAKEAIKNSSR
Sbjct: 541 KLAKPLSSLTPLIIAAKEAIKNSSR 565
>gi|189491755 p21-activated kinase 3 isoform b [Homo sapiens]
Length = 580
Score = 1069 bits (2764), Expect = 0.0
Identities = 544/580 (93%), Positives = 544/580 (93%), Gaps = 36/580 (6%)
Query: 1 MSDGLDNEEKPPAPPLRMNSNNRDSSALNHSSKPLPMAPEEKNKKARLRSIFPGGGDKTN 60
MSDGLDNEEKPPAPPLRMNSNNRDSSALNHSSKPLPMAPEEKNKKARLRSIFPGGGDKTN
Sbjct: 1 MSDGLDNEEKPPAPPLRMNSNNRDSSALNHSSKPLPMAPEEKNKKARLRSIFPGGGDKTN 60
Query: 61 KKKEKERPEISLPSDFEHTIHVGFDAVTGEFT---------------------------- 92
KKKEKERPEISLPSDFEHTIHVGFDAVTGEFT
Sbjct: 61 KKKEKERPEISLPSDFEHTIHVGFDAVTGEFTNSPFQTSRPVTVASSQSEGKMPDLYGSQ 120
Query: 93 --------GIPEQWARLLQTSNITKLEQKKNPQAVLDVLKFYDSKETVNNQKYMSFTSGD 144
GIPEQWARLLQTSNITKLEQKKNPQAVLDVLKFYDSKETVNNQKYMSFTSGD
Sbjct: 121 MCPGKLPEGIPEQWARLLQTSNITKLEQKKNPQAVLDVLKFYDSKETVNNQKYMSFTSGD 180
Query: 145 KSAHGYIAAHPSSTKTASEPPLAPPVSEEEDEEEEEEEDENEPPPVIAPRPEHTKSIYTR 204
KSAHGYIAAHPSSTKTASEPPLAPPVSEEEDEEEEEEEDENEPPPVIAPRPEHTKSIYTR
Sbjct: 181 KSAHGYIAAHPSSTKTASEPPLAPPVSEEEDEEEEEEEDENEPPPVIAPRPEHTKSIYTR 240
Query: 205 SVVESIASPAVPNKEVTPPSAENANSSTLYRNTDRQRKKSKMTDEEILEKLRSIVSVGDP 264
SVVESIASPAVPNKEVTPPSAENANSSTLYRNTDRQRKKSKMTDEEILEKLRSIVSVGDP
Sbjct: 241 SVVESIASPAVPNKEVTPPSAENANSSTLYRNTDRQRKKSKMTDEEILEKLRSIVSVGDP 300
Query: 265 KKKYTRFEKIGQGASGTVYTALDIATGQEVAIKQMNLQQQPKKELIINEILVMRENKNPN 324
KKKYTRFEKIGQGASGTVYTALDIATGQEVAIKQMNLQQQPKKELIINEILVMRENKNPN
Sbjct: 301 KKKYTRFEKIGQGASGTVYTALDIATGQEVAIKQMNLQQQPKKELIINEILVMRENKNPN 360
Query: 325 IVNYLDSYLVGDELWVVMEYLAGGSLTDVVTETCMDEGQIAAVCRECLQALDFLHSNQVI 384
IVNYLDSYLVGDELWVVMEYLAGGSLTDVVTETCMDEGQIAAVCRECLQALDFLHSNQVI
Sbjct: 361 IVNYLDSYLVGDELWVVMEYLAGGSLTDVVTETCMDEGQIAAVCRECLQALDFLHSNQVI 420
Query: 385 HRDIKSDNILLGMDGSVKLTDFGFCAQITPEQSKRSTMVGTPYWMAPEVVTRKAYGPKVD 444
HRDIKSDNILLGMDGSVKLTDFGFCAQITPEQSKRSTMVGTPYWMAPEVVTRKAYGPKVD
Sbjct: 421 HRDIKSDNILLGMDGSVKLTDFGFCAQITPEQSKRSTMVGTPYWMAPEVVTRKAYGPKVD 480
Query: 445 IWSLGIMAIEMVEGEPPYLNENPLRALYLIATNGTPELQNPERLSAVFRDFLNRCLEMDV 504
IWSLGIMAIEMVEGEPPYLNENPLRALYLIATNGTPELQNPERLSAVFRDFLNRCLEMDV
Sbjct: 481 IWSLGIMAIEMVEGEPPYLNENPLRALYLIATNGTPELQNPERLSAVFRDFLNRCLEMDV 540
Query: 505 DRRGSAKELLQHPFLKLAKPLSSLTPLIIAAKEAIKNSSR 544
DRRGSAKELLQHPFLKLAKPLSSLTPLIIAAKEAIKNSSR
Sbjct: 541 DRRGSAKELLQHPFLKLAKPLSSLTPLIIAAKEAIKNSSR 580
>gi|42794769 p21-activated kinase 1 isoform 2 [Homo sapiens]
Length = 545
Score = 872 bits (2252), Expect = 0.0
Identities = 445/552 (80%), Positives = 489/552 (88%), Gaps = 21/552 (3%)
Query: 2 SDGLDNEEKPPAPPLRMNSN-----NRDSSALNHSSKPLPMAPEEKNKKARL-RSIFPGG 55
++GLD ++KPPAPP+R S ++D+ LNH SKPLP PEEK KK R RSI PG
Sbjct: 3 NNGLDIQDKPPAPPMRNTSTMIGAGSKDAGTLNHGSKPLPPNPEEKKKKDRFYRSILPG- 61
Query: 56 GDKTNKKKEKERPEISLPSDFEHTIHVGFDAVTGEFTGIPEQWARLLQTSNITKLEQKKN 115
DKTNKKKEKERPEISLPSDFEHTIHVGFDAVTGEFTG+PEQWARLLQTSNITK EQKKN
Sbjct: 62 -DKTNKKKEKERPEISLPSDFEHTIHVGFDAVTGEFTGMPEQWARLLQTSNITKSEQKKN 120
Query: 116 PQAVLDVLKFYDSKETVNNQKYMSFTSGDKSAHGYIAAHPSSTKTASEPPLAPPVSEEED 175
PQAVLDVL+FY+SK+T N+QKYMSFT DKSA Y +++ + K SE P PPVSE+ED
Sbjct: 121 PQAVLDVLEFYNSKKTSNSQKYMSFT--DKSAEDYNSSNALNVKAVSETPAVPPVSEDED 178
Query: 176 EEEEEEEDENEPPPVIAPRPEHTKSIYTRSVVESIASPAVPNKEV-TPPSAENANSST-- 232
+++ D+ PPPVIAPRPEHTKS+YTRSV+E + P P ++V T P + N++T
Sbjct: 179 DDD----DDATPPPVIAPRPEHTKSVYTRSVIEPL--PVTPTRDVATSPISPTENNTTPP 232
Query: 233 --LYRNTDRQRKKSKMTDEEILEKLRSIVSVGDPKKKYTRFEKIGQGASGTVYTALDIAT 290
L RNT++Q+KK KM+DEEILEKLRSIVSVGDPKKKYTRFEKIGQGASGTVYTA+D+AT
Sbjct: 233 DALTRNTEKQKKKPKMSDEEILEKLRSIVSVGDPKKKYTRFEKIGQGASGTVYTAMDVAT 292
Query: 291 GQEVAIKQMNLQQQPKKELIINEILVMRENKNPNIVNYLDSYLVGDELWVVMEYLAGGSL 350
GQEVAIKQMNLQQQPKKELIINEILVMRENKNPNIVNYLDSYLVGDELWVVMEYLAGGSL
Sbjct: 293 GQEVAIKQMNLQQQPKKELIINEILVMRENKNPNIVNYLDSYLVGDELWVVMEYLAGGSL 352
Query: 351 TDVVTETCMDEGQIAAVCRECLQALDFLHSNQVIHRDIKSDNILLGMDGSVKLTDFGFCA 410
TDVVTETCMDEGQIAAVCRECLQAL+FLHSNQVIHRDIKSDNILLGMDGSVKLTDFGFCA
Sbjct: 353 TDVVTETCMDEGQIAAVCRECLQALEFLHSNQVIHRDIKSDNILLGMDGSVKLTDFGFCA 412
Query: 411 QITPEQSKRSTMVGTPYWMAPEVVTRKAYGPKVDIWSLGIMAIEMVEGEPPYLNENPLRA 470
QITPEQSKRSTMVGTPYWMAPEVVTRKAYGPKVDIWSLGIMAIEM+EGEPPYLNENPLRA
Sbjct: 413 QITPEQSKRSTMVGTPYWMAPEVVTRKAYGPKVDIWSLGIMAIEMIEGEPPYLNENPLRA 472
Query: 471 LYLIATNGTPELQNPERLSAVFRDFLNRCLEMDVDRRGSAKELLQHPFLKLAKPLSSLTP 530
LYLIATNGTPELQNPE+LSA+FRDFLNRCLEMDV++RGSAKELLQH FLK+AKPLSSLTP
Sbjct: 473 LYLIATNGTPELQNPEKLSAIFRDFLNRCLEMDVEKRGSAKELLQHQFLKIAKPLSSLTP 532
Query: 531 LIIAAKEAIKNS 542
LI AAKEA KN+
Sbjct: 533 LIAAAKEATKNN 544
>gi|190886457 p21-activated kinase 1 isoform 1 [Homo sapiens]
Length = 553
Score = 830 bits (2144), Expect = 0.0
Identities = 423/525 (80%), Positives = 465/525 (88%), Gaps = 21/525 (4%)
Query: 2 SDGLDNEEKPPAPPLRMNSN-----NRDSSALNHSSKPLPMAPEEKNKKARL-RSIFPGG 55
++GLD ++KPPAPP+R S ++D+ LNH SKPLP PEEK KK R RSI PG
Sbjct: 3 NNGLDIQDKPPAPPMRNTSTMIGAGSKDAGTLNHGSKPLPPNPEEKKKKDRFYRSILPG- 61
Query: 56 GDKTNKKKEKERPEISLPSDFEHTIHVGFDAVTGEFTGIPEQWARLLQTSNITKLEQKKN 115
DKTNKKKEKERPEISLPSDFEHTIHVGFDAVTGEFTG+PEQWARLLQTSNITK EQKKN
Sbjct: 62 -DKTNKKKEKERPEISLPSDFEHTIHVGFDAVTGEFTGMPEQWARLLQTSNITKSEQKKN 120
Query: 116 PQAVLDVLKFYDSKETVNNQKYMSFTSGDKSAHGYIAAHPSSTKTASEPPLAPPVSEEED 175
PQAVLDVL+FY+SK+T N+QKYMSFT DKSA Y +++ + K SE P PPVSE+ED
Sbjct: 121 PQAVLDVLEFYNSKKTSNSQKYMSFT--DKSAEDYNSSNALNVKAVSETPAVPPVSEDED 178
Query: 176 EEEEEEEDENEPPPVIAPRPEHTKSIYTRSVVESIASPAVPNKEV-TPPSAENANSST-- 232
+++ D+ PPPVIAPRPEHTKS+YTRSV+E + P P ++V T P + N++T
Sbjct: 179 DDD----DDATPPPVIAPRPEHTKSVYTRSVIEPL--PVTPTRDVATSPISPTENNTTPP 232
Query: 233 --LYRNTDRQRKKSKMTDEEILEKLRSIVSVGDPKKKYTRFEKIGQGASGTVYTALDIAT 290
L RNT++Q+KK KM+DEEILEKLRSIVSVGDPKKKYTRFEKIGQGASGTVYTA+D+AT
Sbjct: 233 DALTRNTEKQKKKPKMSDEEILEKLRSIVSVGDPKKKYTRFEKIGQGASGTVYTAMDVAT 292
Query: 291 GQEVAIKQMNLQQQPKKELIINEILVMRENKNPNIVNYLDSYLVGDELWVVMEYLAGGSL 350
GQEVAIKQMNLQQQPKKELIINEILVMRENKNPNIVNYLDSYLVGDELWVVMEYLAGGSL
Sbjct: 293 GQEVAIKQMNLQQQPKKELIINEILVMRENKNPNIVNYLDSYLVGDELWVVMEYLAGGSL 352
Query: 351 TDVVTETCMDEGQIAAVCRECLQALDFLHSNQVIHRDIKSDNILLGMDGSVKLTDFGFCA 410
TDVVTETCMDEGQIAAVCRECLQAL+FLHSNQVIHRDIKSDNILLGMDGSVKLTDFGFCA
Sbjct: 353 TDVVTETCMDEGQIAAVCRECLQALEFLHSNQVIHRDIKSDNILLGMDGSVKLTDFGFCA 412
Query: 411 QITPEQSKRSTMVGTPYWMAPEVVTRKAYGPKVDIWSLGIMAIEMVEGEPPYLNENPLRA 470
QITPEQSKRSTMVGTPYWMAPEVVTRKAYGPKVDIWSLGIMAIEM+EGEPPYLNENPLRA
Sbjct: 413 QITPEQSKRSTMVGTPYWMAPEVVTRKAYGPKVDIWSLGIMAIEMIEGEPPYLNENPLRA 472
Query: 471 LYLIATNGTPELQNPERLSAVFRDFLNRCLEMDVDRRGSAKELLQ 515
LYLIATNGTPELQNPE+LSA+FRDFLNRCLEMDV++RGSAKELLQ
Sbjct: 473 LYLIATNGTPELQNPEKLSAIFRDFLNRCLEMDVEKRGSAKELLQ 517
>gi|32483399 p21-activated kinase 2 [Homo sapiens]
Length = 524
Score = 793 bits (2048), Expect = 0.0
Identities = 407/547 (74%), Positives = 464/547 (84%), Gaps = 29/547 (5%)
Query: 1 MSDGLDNEEKPPAPPLRMNSN-----NRDSSALNHSSKPLPMAPEEKNKKARLRSIFPGG 55
MSD + E+KPPAPP+RM+S +D + NHS KPLP PEEK + ++ SIF G
Sbjct: 1 MSDNGELEDKPPAPPVRMSSTIFSTGGKDPLSANHSLKPLPSVPEEKKPRHKIISIF-SG 59
Query: 56 GDKTNKKKEKERPEISLPSDFEHTIHVGFDAVTGEFTGIPEQWARLLQTSNITKLEQKKN 115
+K +KKKEKERPEIS PSDFEHTIHVGFDAVTGEFTG+PEQWARLLQTSNITKLEQKKN
Sbjct: 60 TEKGSKKKEKERPEISPPSDFEHTIHVGFDAVTGEFTGMPEQWARLLQTSNITKLEQKKN 119
Query: 116 PQAVLDVLKFYDSKETVNNQKYMSFTSGDKSAHGYIAAHPSSTKTASEPPLAPPVSEEED 175
PQAVLDVLKFYDS QKY+SFT +K G+ + P+ +E P V+EEED
Sbjct: 120 PQAVLDVLKFYDSNTV--KQKYLSFTPPEKD--GFPSGTPALNAKGTEAPAV--VTEEED 173
Query: 176 EEEEEEEDENEPPPVIAPRPEHTKSIYTRSVVESIASPAVPNKEVTPPSAENANSSTLYR 235
++EE PPVIAPRP+HTKSIYTRSV++ + +P +++ +
Sbjct: 174 DDEETA------PPVIAPRPDHTKSIYTRSVIDPVPAPV-----------GDSHVDGAAK 216
Query: 236 NTDRQRKKSKMTDEEILEKLRSIVSVGDPKKKYTRFEKIGQGASGTVYTALDIATGQEVA 295
+ D+Q+KK+KMTDEEI+EKLR+IVS+GDPKKKYTR+EKIGQGASGTV+TA D+A GQEVA
Sbjct: 217 SLDKQKKKTKMTDEEIMEKLRTIVSIGDPKKKYTRYEKIGQGASGTVFTATDVALGQEVA 276
Query: 296 IKQMNLQQQPKKELIINEILVMRENKNPNIVNYLDSYLVGDELWVVMEYLAGGSLTDVVT 355
IKQ+NLQ+QPKKELIINEILVM+E KNPNIVN+LDSYLVGDEL+VVMEYLAGGSLTDVVT
Sbjct: 277 IKQINLQKQPKKELIINEILVMKELKNPNIVNFLDSYLVGDELFVVMEYLAGGSLTDVVT 336
Query: 356 ETCMDEGQIAAVCRECLQALDFLHSNQVIHRDIKSDNILLGMDGSVKLTDFGFCAQITPE 415
ETCMDE QIAAVCRECLQAL+FLH+NQVIHRDIKSDN+LLGM+GSVKLTDFGFCAQITPE
Sbjct: 337 ETCMDEAQIAAVCRECLQALEFLHANQVIHRDIKSDNVLLGMEGSVKLTDFGFCAQITPE 396
Query: 416 QSKRSTMVGTPYWMAPEVVTRKAYGPKVDIWSLGIMAIEMVEGEPPYLNENPLRALYLIA 475
QSKRSTMVGTPYWMAPEVVTRKAYGPKVDIWSLGIMAIEMVEGEPPYLNENPLRALYLIA
Sbjct: 397 QSKRSTMVGTPYWMAPEVVTRKAYGPKVDIWSLGIMAIEMVEGEPPYLNENPLRALYLIA 456
Query: 476 TNGTPELQNPERLSAVFRDFLNRCLEMDVDRRGSAKELLQHPFLKLAKPLSSLTPLIIAA 535
TNGTPELQNPE+LS +FRDFLNRCLEMDV++RGSAKELLQHPFLKLAKPLSSLTPLI+AA
Sbjct: 457 TNGTPELQNPEKLSPIFRDFLNRCLEMDVEKRGSAKELLQHPFLKLAKPLSSLTPLIMAA 516
Query: 536 KEAIKNS 542
KEA+K++
Sbjct: 517 KEAMKSN 523
>gi|62422561 p21-activated kinase 4 isoform 2 [Homo sapiens]
Length = 438
Score = 359 bits (922), Expect = 3e-99
Identities = 199/470 (42%), Positives = 280/470 (59%), Gaps = 41/470 (8%)
Query: 63 KEKERPEISLPSDFEHTIHVGFDAVTGEFTGIPEQWARLLQTSNITKLEQKKNPQAVLDV 122
K K+R EIS PS+FEH +H GFD +FTG+P QW L++ E + P+ ++D
Sbjct: 4 KRKKRVEISAPSNFEHRVHTGFDQHEQKFTGLPRQWQSLIE-------ESARRPKPLVDP 56
Query: 123 LKFYDSKETVNNQKYMSFTSGDKSAHGYIAAHPSSTKTASEPPLAPPVSEEEDEEEEEEE 182
+ + SA G A P S+ ++S PP +
Sbjct: 57 ACITSIQPGAPKGEPHDVAPNGPSAGGL--AIPQSSSSSSRPPTRARGAPSPGVLGPHAS 114
Query: 183 DENEPPPVIAPRPEHTKSIYTRSVVESIASPAVPNKEVTPPSAENANSSTLYRNTDRQRK 242
+ PP P A+PAVP PP + QR+
Sbjct: 115 EPQLAPPACTP-----------------AAPAVPG----PPGPRSP-----------QRE 142
Query: 243 KSKMTDEEILEKLRSIVSVGDPKKKYTRFEKIGQGASGTVYTALDIATGQEVAIKQMNLQ 302
+++ E+ L+ +V GDP+ F KIG+G++G V A ++G+ VA+K+M+L+
Sbjct: 143 PQRVSHEQFRAALQLVVDPGDPRSYLDNFIKIGEGSTGIVCIATVRSSGKLVAVKKMDLR 202
Query: 303 QQPKKELIINEILVMRENKNPNIVNYLDSYLVGDELWVVMEYLAGGSLTDVVTETCMDEG 362
+Q ++EL+ NE+++MR+ ++ N+V +SYLVGDELWVVME+L GG+LTD+VT T M+E
Sbjct: 203 KQQRRELLFNEVVIMRDYQHENVVEMYNSYLVGDELWVVMEFLEGGALTDIVTHTRMNEE 262
Query: 363 QIAAVCRECLQALDFLHSNQVIHRDIKSDNILLGMDGSVKLTDFGFCAQITPEQSKRSTM 422
QIAAVC LQAL LH+ VIHRDIKSD+ILL DG VKL+DFGFCAQ++ E +R ++
Sbjct: 263 QIAAVCLAVLQALSVLHAQGVIHRDIKSDSILLTHDGRVKLSDFGFCAQVSKEVPRRKSL 322
Query: 423 VGTPYWMAPEVVTRKAYGPKVDIWSLGIMAIEMVEGEPPYLNENPLRALYLIATNGTPEL 482
VGTPYWMAPE+++R YGP+VDIWSLGIM IEMV+GEPPY NE PL+A+ +I N P L
Sbjct: 323 VGTPYWMAPELISRLPYGPEVDIWSLGIMVIEMVDGEPPYFNEPPLKAMKMIRDNLPPRL 382
Query: 483 QNPERLSAVFRDFLNRCLEMDVDRRGSAKELLQHPFLKLAKPLSSLTPLI 532
+N ++S + FL+R L D +R +A ELL+HPFL A P +S+ PL+
Sbjct: 383 KNLHKVSPSLKGFLDRLLVRDPAQRATAAELLKHPFLAKAGPPASIVPLM 432
>gi|62422563 p21-activated kinase 4 isoform 2 [Homo sapiens]
Length = 438
Score = 359 bits (922), Expect = 3e-99
Identities = 199/470 (42%), Positives = 280/470 (59%), Gaps = 41/470 (8%)
Query: 63 KEKERPEISLPSDFEHTIHVGFDAVTGEFTGIPEQWARLLQTSNITKLEQKKNPQAVLDV 122
K K+R EIS PS+FEH +H GFD +FTG+P QW L++ E + P+ ++D
Sbjct: 4 KRKKRVEISAPSNFEHRVHTGFDQHEQKFTGLPRQWQSLIE-------ESARRPKPLVDP 56
Query: 123 LKFYDSKETVNNQKYMSFTSGDKSAHGYIAAHPSSTKTASEPPLAPPVSEEEDEEEEEEE 182
+ + SA G A P S+ ++S PP +
Sbjct: 57 ACITSIQPGAPKGEPHDVAPNGPSAGGL--AIPQSSSSSSRPPTRARGAPSPGVLGPHAS 114
Query: 183 DENEPPPVIAPRPEHTKSIYTRSVVESIASPAVPNKEVTPPSAENANSSTLYRNTDRQRK 242
+ PP P A+PAVP PP + QR+
Sbjct: 115 EPQLAPPACTP-----------------AAPAVPG----PPGPRSP-----------QRE 142
Query: 243 KSKMTDEEILEKLRSIVSVGDPKKKYTRFEKIGQGASGTVYTALDIATGQEVAIKQMNLQ 302
+++ E+ L+ +V GDP+ F KIG+G++G V A ++G+ VA+K+M+L+
Sbjct: 143 PQRVSHEQFRAALQLVVDPGDPRSYLDNFIKIGEGSTGIVCIATVRSSGKLVAVKKMDLR 202
Query: 303 QQPKKELIINEILVMRENKNPNIVNYLDSYLVGDELWVVMEYLAGGSLTDVVTETCMDEG 362
+Q ++EL+ NE+++MR+ ++ N+V +SYLVGDELWVVME+L GG+LTD+VT T M+E
Sbjct: 203 KQQRRELLFNEVVIMRDYQHENVVEMYNSYLVGDELWVVMEFLEGGALTDIVTHTRMNEE 262
Query: 363 QIAAVCRECLQALDFLHSNQVIHRDIKSDNILLGMDGSVKLTDFGFCAQITPEQSKRSTM 422
QIAAVC LQAL LH+ VIHRDIKSD+ILL DG VKL+DFGFCAQ++ E +R ++
Sbjct: 263 QIAAVCLAVLQALSVLHAQGVIHRDIKSDSILLTHDGRVKLSDFGFCAQVSKEVPRRKSL 322
Query: 423 VGTPYWMAPEVVTRKAYGPKVDIWSLGIMAIEMVEGEPPYLNENPLRALYLIATNGTPEL 482
VGTPYWMAPE+++R YGP+VDIWSLGIM IEMV+GEPPY NE PL+A+ +I N P L
Sbjct: 323 VGTPYWMAPELISRLPYGPEVDIWSLGIMVIEMVDGEPPYFNEPPLKAMKMIRDNLPPRL 382
Query: 483 QNPERLSAVFRDFLNRCLEMDVDRRGSAKELLQHPFLKLAKPLSSLTPLI 532
+N ++S + FL+R L D +R +A ELL+HPFL A P +S+ PL+
Sbjct: 383 KNLHKVSPSLKGFLDRLLVRDPAQRATAAELLKHPFLAKAGPPASIVPLM 432
>gi|62422554 p21-activated kinase 4 isoform 1 [Homo sapiens]
Length = 591
Score = 319 bits (818), Expect = 4e-87
Identities = 171/380 (45%), Positives = 239/380 (62%), Gaps = 32/380 (8%)
Query: 153 AHPSSTKTASEPPLAPPVSEEEDEEEEEEEDENEPPPVIAPRPEHTKSIYTRSVVESIAS 212
A P S+ ++S PP + + PP P A+
Sbjct: 238 AIPQSSSSSSRPPTRARGAPSPGVLGPHASEPQLAPPACTP-----------------AA 280
Query: 213 PAVPNKEVTPPSAENANSSTLYRNTDRQRKKSKMTDEEILEKLRSIVSVGDPKKKYTRFE 272
PAVP PP + QR+ +++ E+ L+ +V GDP+ F
Sbjct: 281 PAVPG----PPGPRSP-----------QREPQRVSHEQFRAALQLVVDPGDPRSYLDNFI 325
Query: 273 KIGQGASGTVYTALDIATGQEVAIKQMNLQQQPKKELIINEILVMRENKNPNIVNYLDSY 332
KIG+G++G V A ++G+ VA+K+M+L++Q ++EL+ NE+++MR+ ++ N+V +SY
Sbjct: 326 KIGEGSTGIVCIATVRSSGKLVAVKKMDLRKQQRRELLFNEVVIMRDYQHENVVEMYNSY 385
Query: 333 LVGDELWVVMEYLAGGSLTDVVTETCMDEGQIAAVCRECLQALDFLHSNQVIHRDIKSDN 392
LVGDELWVVME+L GG+LTD+VT T M+E QIAAVC LQAL LH+ VIHRDIKSD+
Sbjct: 386 LVGDELWVVMEFLEGGALTDIVTHTRMNEEQIAAVCLAVLQALSVLHAQGVIHRDIKSDS 445
Query: 393 ILLGMDGSVKLTDFGFCAQITPEQSKRSTMVGTPYWMAPEVVTRKAYGPKVDIWSLGIMA 452
ILL DG VKL+DFGFCAQ++ E +R ++VGTPYWMAPE+++R YGP+VDIWSLGIM
Sbjct: 446 ILLTHDGRVKLSDFGFCAQVSKEVPRRKSLVGTPYWMAPELISRLPYGPEVDIWSLGIMV 505
Query: 453 IEMVEGEPPYLNENPLRALYLIATNGTPELQNPERLSAVFRDFLNRCLEMDVDRRGSAKE 512
IEMV+GEPPY NE PL+A+ +I N P L+N ++S + FL+R L D +R +A E
Sbjct: 506 IEMVDGEPPYFNEPPLKAMKMIRDNLPPRLKNLHKVSPSLKGFLDRLLVRDPAQRATAAE 565
Query: 513 LLQHPFLKLAKPLSSLTPLI 532
LL+HPFL A P +S+ PL+
Sbjct: 566 LLKHPFLAKAGPPASIVPLM 585
Score = 54.7 bits (130), Expect = 2e-07
Identities = 23/43 (53%), Positives = 30/43 (69%)
Query: 63 KEKERPEISLPSDFEHTIHVGFDAVTGEFTGIPEQWARLLQTS 105
K K+R EIS PS+FEH +H GFD +FTG+P QW L++ S
Sbjct: 4 KRKKRVEISAPSNFEHRVHTGFDQHEQKFTGLPRQWQSLIEES 46
>gi|62422557 p21-activated kinase 4 isoform 1 [Homo sapiens]
Length = 591
Score = 319 bits (818), Expect = 4e-87
Identities = 171/380 (45%), Positives = 239/380 (62%), Gaps = 32/380 (8%)
Query: 153 AHPSSTKTASEPPLAPPVSEEEDEEEEEEEDENEPPPVIAPRPEHTKSIYTRSVVESIAS 212
A P S+ ++S PP + + PP P A+
Sbjct: 238 AIPQSSSSSSRPPTRARGAPSPGVLGPHASEPQLAPPACTP-----------------AA 280
Query: 213 PAVPNKEVTPPSAENANSSTLYRNTDRQRKKSKMTDEEILEKLRSIVSVGDPKKKYTRFE 272
PAVP PP + QR+ +++ E+ L+ +V GDP+ F
Sbjct: 281 PAVPG----PPGPRSP-----------QREPQRVSHEQFRAALQLVVDPGDPRSYLDNFI 325
Query: 273 KIGQGASGTVYTALDIATGQEVAIKQMNLQQQPKKELIINEILVMRENKNPNIVNYLDSY 332
KIG+G++G V A ++G+ VA+K+M+L++Q ++EL+ NE+++MR+ ++ N+V +SY
Sbjct: 326 KIGEGSTGIVCIATVRSSGKLVAVKKMDLRKQQRRELLFNEVVIMRDYQHENVVEMYNSY 385
Query: 333 LVGDELWVVMEYLAGGSLTDVVTETCMDEGQIAAVCRECLQALDFLHSNQVIHRDIKSDN 392
LVGDELWVVME+L GG+LTD+VT T M+E QIAAVC LQAL LH+ VIHRDIKSD+
Sbjct: 386 LVGDELWVVMEFLEGGALTDIVTHTRMNEEQIAAVCLAVLQALSVLHAQGVIHRDIKSDS 445
Query: 393 ILLGMDGSVKLTDFGFCAQITPEQSKRSTMVGTPYWMAPEVVTRKAYGPKVDIWSLGIMA 452
ILL DG VKL+DFGFCAQ++ E +R ++VGTPYWMAPE+++R YGP+VDIWSLGIM
Sbjct: 446 ILLTHDGRVKLSDFGFCAQVSKEVPRRKSLVGTPYWMAPELISRLPYGPEVDIWSLGIMV 505
Query: 453 IEMVEGEPPYLNENPLRALYLIATNGTPELQNPERLSAVFRDFLNRCLEMDVDRRGSAKE 512
IEMV+GEPPY NE PL+A+ +I N P L+N ++S + FL+R L D +R +A E
Sbjct: 506 IEMVDGEPPYFNEPPLKAMKMIRDNLPPRLKNLHKVSPSLKGFLDRLLVRDPAQRATAAE 565
Query: 513 LLQHPFLKLAKPLSSLTPLI 532
LL+HPFL A P +S+ PL+
Sbjct: 566 LLKHPFLAKAGPPASIVPLM 585
Score = 54.7 bits (130), Expect = 2e-07
Identities = 23/43 (53%), Positives = 30/43 (69%)
Query: 63 KEKERPEISLPSDFEHTIHVGFDAVTGEFTGIPEQWARLLQTS 105
K K+R EIS PS+FEH +H GFD +FTG+P QW L++ S
Sbjct: 4 KRKKRVEISAPSNFEHRVHTGFDQHEQKFTGLPRQWQSLIEES 46
>gi|5031975 p21-activated kinase 4 isoform 1 [Homo sapiens]
Length = 591
Score = 319 bits (818), Expect = 4e-87
Identities = 171/380 (45%), Positives = 239/380 (62%), Gaps = 32/380 (8%)
Query: 153 AHPSSTKTASEPPLAPPVSEEEDEEEEEEEDENEPPPVIAPRPEHTKSIYTRSVVESIAS 212
A P S+ ++S PP + + PP P A+
Sbjct: 238 AIPQSSSSSSRPPTRARGAPSPGVLGPHASEPQLAPPACTP-----------------AA 280
Query: 213 PAVPNKEVTPPSAENANSSTLYRNTDRQRKKSKMTDEEILEKLRSIVSVGDPKKKYTRFE 272
PAVP PP + QR+ +++ E+ L+ +V GDP+ F
Sbjct: 281 PAVPG----PPGPRSP-----------QREPQRVSHEQFRAALQLVVDPGDPRSYLDNFI 325
Query: 273 KIGQGASGTVYTALDIATGQEVAIKQMNLQQQPKKELIINEILVMRENKNPNIVNYLDSY 332
KIG+G++G V A ++G+ VA+K+M+L++Q ++EL+ NE+++MR+ ++ N+V +SY
Sbjct: 326 KIGEGSTGIVCIATVRSSGKLVAVKKMDLRKQQRRELLFNEVVIMRDYQHENVVEMYNSY 385
Query: 333 LVGDELWVVMEYLAGGSLTDVVTETCMDEGQIAAVCRECLQALDFLHSNQVIHRDIKSDN 392
LVGDELWVVME+L GG+LTD+VT T M+E QIAAVC LQAL LH+ VIHRDIKSD+
Sbjct: 386 LVGDELWVVMEFLEGGALTDIVTHTRMNEEQIAAVCLAVLQALSVLHAQGVIHRDIKSDS 445
Query: 393 ILLGMDGSVKLTDFGFCAQITPEQSKRSTMVGTPYWMAPEVVTRKAYGPKVDIWSLGIMA 452
ILL DG VKL+DFGFCAQ++ E +R ++VGTPYWMAPE+++R YGP+VDIWSLGIM
Sbjct: 446 ILLTHDGRVKLSDFGFCAQVSKEVPRRKSLVGTPYWMAPELISRLPYGPEVDIWSLGIMV 505
Query: 453 IEMVEGEPPYLNENPLRALYLIATNGTPELQNPERLSAVFRDFLNRCLEMDVDRRGSAKE 512
IEMV+GEPPY NE PL+A+ +I N P L+N ++S + FL+R L D +R +A E
Sbjct: 506 IEMVDGEPPYFNEPPLKAMKMIRDNLPPRLKNLHKVSPSLKGFLDRLLVRDPAQRATAAE 565
Query: 513 LLQHPFLKLAKPLSSLTPLI 532
LL+HPFL A P +S+ PL+
Sbjct: 566 LLKHPFLAKAGPPASIVPLM 585
Score = 54.7 bits (130), Expect = 2e-07
Identities = 23/43 (53%), Positives = 30/43 (69%)
Query: 63 KEKERPEISLPSDFEHTIHVGFDAVTGEFTGIPEQWARLLQTS 105
K K+R EIS PS+FEH +H GFD +FTG+P QW L++ S
Sbjct: 4 KRKKRVEISAPSNFEHRVHTGFDQHEQKFTGLPRQWQSLIEES 46
>gi|29826329 p21-activated kinase 7 [Homo sapiens]
Length = 719
Score = 316 bits (809), Expect = 4e-86
Identities = 152/292 (52%), Positives = 218/292 (74%)
Query: 241 RKKSKMTDEEILEKLRSIVSVGDPKKKYTRFEKIGQGASGTVYTALDIATGQEVAIKQMN 300
++ S+++ E+ L+ +VS GDP++ F KIG+G++G V A + TG++VA+K+M+
Sbjct: 422 QQPSRVSHEQFRAALQLVVSPGDPREYLANFIKIGEGSTGIVCIATEKHTGKQVAVKKMD 481
Query: 301 LQQQPKKELIINEILVMRENKNPNIVNYLDSYLVGDELWVVMEYLAGGSLTDVVTETCMD 360
L++Q ++EL+ NE+++MR+ + N+V+ SYLVGDELWVVME+L GG+LTD+VT T M+
Sbjct: 482 LRKQQRRELLFNEVVIMRDYHHDNVVDMYSSYLVGDELWVVMEFLEGGALTDIVTHTRMN 541
Query: 361 EGQIAAVCRECLQALDFLHSNQVIHRDIKSDNILLGMDGSVKLTDFGFCAQITPEQSKRS 420
E QIA VC L+AL +LH+ VIHRDIKSD+ILL DG +KL+DFGFCAQ++ E KR
Sbjct: 542 EEQIATVCLSVLRALSYLHNQGVIHRDIKSDSILLTSDGRIKLSDFGFCAQVSKEVPKRK 601
Query: 421 TMVGTPYWMAPEVVTRKAYGPKVDIWSLGIMAIEMVEGEPPYLNENPLRALYLIATNGTP 480
++VGTPYWMAPEV++R YG +VDIWSLGIM IEM++GEPPY NE PL+A+ I + P
Sbjct: 602 SLVGTPYWMAPEVISRLPYGTEVDIWSLGIMVIEMIDGEPPYFNEPPLQAMRRIRDSLPP 661
Query: 481 ELQNPERLSAVFRDFLNRCLEMDVDRRGSAKELLQHPFLKLAKPLSSLTPLI 532
+++ ++S+V R FL+ L + +R +A+ELL HPFLKLA P S + PL+
Sbjct: 662 RVKDLHKVSSVLRGFLDLMLVREPSQRATAQELLGHPFLKLAGPPSCIVPLM 713
Score = 52.4 bits (124), Expect = 1e-06
Identities = 25/48 (52%), Positives = 34/48 (70%), Gaps = 1/48 (2%)
Query: 63 KEKERPEISLPSDFEHTIHVGFDAVTGEFTGIPEQWARLL-QTSNITK 109
K+K++ EIS PS+FEH +H GFD +FTG+P+QW LL T+N K
Sbjct: 4 KKKKKIEISGPSNFEHRVHTGFDPQEQKFTGLPQQWHSLLADTANRPK 51
>gi|24308191 p21-activated kinase 7 [Homo sapiens]
Length = 719
Score = 316 bits (809), Expect = 4e-86
Identities = 152/292 (52%), Positives = 218/292 (74%)
Query: 241 RKKSKMTDEEILEKLRSIVSVGDPKKKYTRFEKIGQGASGTVYTALDIATGQEVAIKQMN 300
++ S+++ E+ L+ +VS GDP++ F KIG+G++G V A + TG++VA+K+M+
Sbjct: 422 QQPSRVSHEQFRAALQLVVSPGDPREYLANFIKIGEGSTGIVCIATEKHTGKQVAVKKMD 481
Query: 301 LQQQPKKELIINEILVMRENKNPNIVNYLDSYLVGDELWVVMEYLAGGSLTDVVTETCMD 360
L++Q ++EL+ NE+++MR+ + N+V+ SYLVGDELWVVME+L GG+LTD+VT T M+
Sbjct: 482 LRKQQRRELLFNEVVIMRDYHHDNVVDMYSSYLVGDELWVVMEFLEGGALTDIVTHTRMN 541
Query: 361 EGQIAAVCRECLQALDFLHSNQVIHRDIKSDNILLGMDGSVKLTDFGFCAQITPEQSKRS 420
E QIA VC L+AL +LH+ VIHRDIKSD+ILL DG +KL+DFGFCAQ++ E KR
Sbjct: 542 EEQIATVCLSVLRALSYLHNQGVIHRDIKSDSILLTSDGRIKLSDFGFCAQVSKEVPKRK 601
Query: 421 TMVGTPYWMAPEVVTRKAYGPKVDIWSLGIMAIEMVEGEPPYLNENPLRALYLIATNGTP 480
++VGTPYWMAPEV++R YG +VDIWSLGIM IEM++GEPPY NE PL+A+ I + P
Sbjct: 602 SLVGTPYWMAPEVISRLPYGTEVDIWSLGIMVIEMIDGEPPYFNEPPLQAMRRIRDSLPP 661
Query: 481 ELQNPERLSAVFRDFLNRCLEMDVDRRGSAKELLQHPFLKLAKPLSSLTPLI 532
+++ ++S+V R FL+ L + +R +A+ELL HPFLKLA P S + PL+
Sbjct: 662 RVKDLHKVSSVLRGFLDLMLVREPSQRATAQELLGHPFLKLAGPPSCIVPLM 713
Score = 52.4 bits (124), Expect = 1e-06
Identities = 25/48 (52%), Positives = 34/48 (70%), Gaps = 1/48 (2%)
Query: 63 KEKERPEISLPSDFEHTIHVGFDAVTGEFTGIPEQWARLL-QTSNITK 109
K+K++ EIS PS+FEH +H GFD +FTG+P+QW LL T+N K
Sbjct: 4 KKKKKIEISGPSNFEHRVHTGFDPQEQKFTGLPQQWHSLLADTANRPK 51
>gi|191252782 p21-activated kinase 6 [Homo sapiens]
Length = 681
Score = 302 bits (774), Expect = 5e-82
Identities = 165/400 (41%), Positives = 243/400 (60%), Gaps = 20/400 (5%)
Query: 153 AHPSSTKTASEPPLAPPVSEEEDEEEE--------EEEDENEPPPVIAPRPEHTKSIYTR 204
A PSS+K P P S +++ + ++P +P S +
Sbjct: 272 APPSSSKPGPPPQSKPNSSFRPPQKDNPPSLVAKAQSLPSDQPVGTFSPLTTSDTSSPQK 331
Query: 205 SVVESIASPAVPNKEVTPPSAEN----ANSSTLYRNTDRQRKKSKM--------TDEEIL 252
S+ + A+ +P + S ++S LY D K + T E+
Sbjct: 332 SLRTAPATGQLPGRSSPAGSPRTWHAQISTSNLYLPQDPTVAKGALAGEDTGVVTHEQFK 391
Query: 253 EKLRSIVSVGDPKKKYTRFEKIGQGASGTVYTALDIATGQEVAIKQMNLQQQPKKELIIN 312
LR +V GDP+ + KIG+G++G V A + +G++VA+K M+L++Q ++EL+ N
Sbjct: 392 AALRMVVDQGDPRLLLDSYVKIGEGSTGIVCLAREKHSGRQVAVKMMDLRKQQRRELLFN 451
Query: 313 EILVMRENKNPNIVNYLDSYLVGDELWVVMEYLAGGSLTDVVTETCMDEGQIAAVCRECL 372
E+++MR+ ++ N+V SYLVG+ELWV+ME+L GG+LTD+V++ ++E QIA VC L
Sbjct: 452 EVVIMRDYQHFNVVEMYKSYLVGEELWVLMEFLQGGALTDIVSQVRLNEEQIATVCEAVL 511
Query: 373 QALDFLHSNQVIHRDIKSDNILLGMDGSVKLTDFGFCAQITPEQSKRSTMVGTPYWMAPE 432
QAL +LH+ VIHRDIKSD+ILL +DG VKL+DFGFCAQI+ + KR ++VGTPYWMAPE
Sbjct: 512 QALAYLHAQGVIHRDIKSDSILLTLDGRVKLSDFGFCAQISKDVPKRKSLVGTPYWMAPE 571
Query: 433 VVTRKAYGPKVDIWSLGIMAIEMVEGEPPYLNENPLRALYLIATNGTPELQNPERLSAVF 492
V++R Y +VDIWSLGIM IEMV+GEPPY +++P++A+ + + P+L+N ++S V
Sbjct: 572 VISRSLYATEVDIWSLGIMVIEMVDGEPPYFSDSPVQAMKRLRDSPPPKLKNSHKVSPVL 631
Query: 493 RDFLNRCLEMDVDRRGSAKELLQHPFLKLAKPLSSLTPLI 532
RDFL R L D R +A+ELL HPFL L PLI
Sbjct: 632 RDFLERMLVRDPQERATAQELLDHPFLLQTGLPECLVPLI 671
Score = 57.8 bits (138), Expect = 3e-08
Identities = 22/44 (50%), Positives = 31/44 (70%)
Query: 61 KKKEKERPEISLPSDFEHTIHVGFDAVTGEFTGIPEQWARLLQT 104
+KK+K+RPEIS P +F+H +H FD G+F G+P QW +L T
Sbjct: 3 RKKKKKRPEISAPQNFQHRVHTSFDPKEGKFVGLPPQWQNILDT 46
>gi|191252780 p21-activated kinase 6 [Homo sapiens]
Length = 681
Score = 302 bits (774), Expect = 5e-82
Identities = 165/400 (41%), Positives = 243/400 (60%), Gaps = 20/400 (5%)
Query: 153 AHPSSTKTASEPPLAPPVSEEEDEEEE--------EEEDENEPPPVIAPRPEHTKSIYTR 204
A PSS+K P P S +++ + ++P +P S +
Sbjct: 272 APPSSSKPGPPPQSKPNSSFRPPQKDNPPSLVAKAQSLPSDQPVGTFSPLTTSDTSSPQK 331
Query: 205 SVVESIASPAVPNKEVTPPSAEN----ANSSTLYRNTDRQRKKSKM--------TDEEIL 252
S+ + A+ +P + S ++S LY D K + T E+
Sbjct: 332 SLRTAPATGQLPGRSSPAGSPRTWHAQISTSNLYLPQDPTVAKGALAGEDTGVVTHEQFK 391
Query: 253 EKLRSIVSVGDPKKKYTRFEKIGQGASGTVYTALDIATGQEVAIKQMNLQQQPKKELIIN 312
LR +V GDP+ + KIG+G++G V A + +G++VA+K M+L++Q ++EL+ N
Sbjct: 392 AALRMVVDQGDPRLLLDSYVKIGEGSTGIVCLAREKHSGRQVAVKMMDLRKQQRRELLFN 451
Query: 313 EILVMRENKNPNIVNYLDSYLVGDELWVVMEYLAGGSLTDVVTETCMDEGQIAAVCRECL 372
E+++MR+ ++ N+V SYLVG+ELWV+ME+L GG+LTD+V++ ++E QIA VC L
Sbjct: 452 EVVIMRDYQHFNVVEMYKSYLVGEELWVLMEFLQGGALTDIVSQVRLNEEQIATVCEAVL 511
Query: 373 QALDFLHSNQVIHRDIKSDNILLGMDGSVKLTDFGFCAQITPEQSKRSTMVGTPYWMAPE 432
QAL +LH+ VIHRDIKSD+ILL +DG VKL+DFGFCAQI+ + KR ++VGTPYWMAPE
Sbjct: 512 QALAYLHAQGVIHRDIKSDSILLTLDGRVKLSDFGFCAQISKDVPKRKSLVGTPYWMAPE 571
Query: 433 VVTRKAYGPKVDIWSLGIMAIEMVEGEPPYLNENPLRALYLIATNGTPELQNPERLSAVF 492
V++R Y +VDIWSLGIM IEMV+GEPPY +++P++A+ + + P+L+N ++S V
Sbjct: 572 VISRSLYATEVDIWSLGIMVIEMVDGEPPYFSDSPVQAMKRLRDSPPPKLKNSHKVSPVL 631
Query: 493 RDFLNRCLEMDVDRRGSAKELLQHPFLKLAKPLSSLTPLI 532
RDFL R L D R +A+ELL HPFL L PLI
Sbjct: 632 RDFLERMLVRDPQERATAQELLDHPFLLQTGLPECLVPLI 671
Score = 57.8 bits (138), Expect = 3e-08
Identities = 22/44 (50%), Positives = 31/44 (70%)
Query: 61 KKKEKERPEISLPSDFEHTIHVGFDAVTGEFTGIPEQWARLLQT 104
+KK+K+RPEIS P +F+H +H FD G+F G+P QW +L T
Sbjct: 3 RKKKKKRPEISAPQNFQHRVHTSFDPKEGKFVGLPPQWQNILDT 46
>gi|9910476 p21-activated kinase 6 [Homo sapiens]
Length = 681
Score = 302 bits (774), Expect = 5e-82
Identities = 165/400 (41%), Positives = 243/400 (60%), Gaps = 20/400 (5%)
Query: 153 AHPSSTKTASEPPLAPPVSEEEDEEEE--------EEEDENEPPPVIAPRPEHTKSIYTR 204
A PSS+K P P S +++ + ++P +P S +
Sbjct: 272 APPSSSKPGPPPQSKPNSSFRPPQKDNPPSLVAKAQSLPSDQPVGTFSPLTTSDTSSPQK 331
Query: 205 SVVESIASPAVPNKEVTPPSAEN----ANSSTLYRNTDRQRKKSKM--------TDEEIL 252
S+ + A+ +P + S ++S LY D K + T E+
Sbjct: 332 SLRTAPATGQLPGRSSPAGSPRTWHAQISTSNLYLPQDPTVAKGALAGEDTGVVTHEQFK 391
Query: 253 EKLRSIVSVGDPKKKYTRFEKIGQGASGTVYTALDIATGQEVAIKQMNLQQQPKKELIIN 312
LR +V GDP+ + KIG+G++G V A + +G++VA+K M+L++Q ++EL+ N
Sbjct: 392 AALRMVVDQGDPRLLLDSYVKIGEGSTGIVCLAREKHSGRQVAVKMMDLRKQQRRELLFN 451
Query: 313 EILVMRENKNPNIVNYLDSYLVGDELWVVMEYLAGGSLTDVVTETCMDEGQIAAVCRECL 372
E+++MR+ ++ N+V SYLVG+ELWV+ME+L GG+LTD+V++ ++E QIA VC L
Sbjct: 452 EVVIMRDYQHFNVVEMYKSYLVGEELWVLMEFLQGGALTDIVSQVRLNEEQIATVCEAVL 511
Query: 373 QALDFLHSNQVIHRDIKSDNILLGMDGSVKLTDFGFCAQITPEQSKRSTMVGTPYWMAPE 432
QAL +LH+ VIHRDIKSD+ILL +DG VKL+DFGFCAQI+ + KR ++VGTPYWMAPE
Sbjct: 512 QALAYLHAQGVIHRDIKSDSILLTLDGRVKLSDFGFCAQISKDVPKRKSLVGTPYWMAPE 571
Query: 433 VVTRKAYGPKVDIWSLGIMAIEMVEGEPPYLNENPLRALYLIATNGTPELQNPERLSAVF 492
V++R Y +VDIWSLGIM IEMV+GEPPY +++P++A+ + + P+L+N ++S V
Sbjct: 572 VISRSLYATEVDIWSLGIMVIEMVDGEPPYFSDSPVQAMKRLRDSPPPKLKNSHKVSPVL 631
Query: 493 RDFLNRCLEMDVDRRGSAKELLQHPFLKLAKPLSSLTPLI 532
RDFL R L D R +A+ELL HPFL L PLI
Sbjct: 632 RDFLERMLVRDPQERATAQELLDHPFLLQTGLPECLVPLI 671
Score = 57.8 bits (138), Expect = 3e-08
Identities = 22/44 (50%), Positives = 31/44 (70%)
Query: 61 KKKEKERPEISLPSDFEHTIHVGFDAVTGEFTGIPEQWARLLQT 104
+KK+K+RPEIS P +F+H +H FD G+F G+P QW +L T
Sbjct: 3 RKKKKKRPEISAPQNFQHRVHTSFDPKEGKFVGLPPQWQNILDT 46
>gi|103471999 serine/threonine kinase 3 [Homo sapiens]
Length = 491
Score = 244 bits (623), Expect = 1e-64
Identities = 123/288 (42%), Positives = 185/288 (64%), Gaps = 4/288 (1%)
Query: 252 LEKLRSIVSVGDPKKKYTRFEKIGQGASGTVYTALDIATGQEVAIKQMNLQQQPKKELII 311
L+KL P++ + EK+G+G+ G+V+ A+ +GQ VAIKQ+ ++ ++ II
Sbjct: 11 LKKLSEDSLTKQPEEVFDVLEKLGEGSYGSVFKAIHKESGQVVAIKQVPVESDLQE--II 68
Query: 312 NEILVMRENKNPNIVNYLDSYLVGDELWVVMEYLAGGSLTDVVT--ETCMDEGQIAAVCR 369
EI +M++ +P +V Y SY +LW+VMEY GS++D++ + E +IA + +
Sbjct: 69 KEISIMQQCDSPYVVKYYGSYFKNTDLWIVMEYCGAGSVSDIIRLRNKTLIEDEIATILK 128
Query: 370 ECLQALDFLHSNQVIHRDIKSDNILLGMDGSVKLTDFGFCAQITPEQSKRSTMVGTPYWM 429
L+ L++LH + IHRDIK+ NILL +G KL DFG Q+T +KR+T++GTP+WM
Sbjct: 129 STLKGLEYLHFMRKIHRDIKAGNILLNTEGHAKLADFGVAGQLTDTMAKRNTVIGTPFWM 188
Query: 430 APEVVTRKAYGPKVDIWSLGIMAIEMVEGEPPYLNENPLRALYLIATNGTPELQNPERLS 489
APEV+ Y DIWSLGI +IEM EG+PPY + +P+RA+++I TN P + PE S
Sbjct: 189 APEVIQEIGYNCVADIWSLGITSIEMAEGKPPYADIHPMRAIFMIPTNPPPTFRKPELWS 248
Query: 490 AVFRDFLNRCLEMDVDRRGSAKELLQHPFLKLAKPLSSLTPLIIAAKE 537
F DF+ +CL + ++R +A +LLQHPF+K AKP+S L LI A E
Sbjct: 249 DDFTDFVKKCLVKNPEQRATATQLLQHPFIKNAKPVSILRDLITEAME 296
>gi|5454096 serine/threonine kinase 4 [Homo sapiens]
Length = 487
Score = 244 bits (623), Expect = 1e-64
Identities = 126/299 (42%), Positives = 189/299 (63%), Gaps = 12/299 (4%)
Query: 241 RKKSKMTDEEILEKLRSIVSVGDPKKKYTRFEKIGQGASGTVYTALDIATGQEVAIKQMN 300
R++ K DE+ L K P++ + EK+G+G+ G+VY A+ TGQ VAIKQ+
Sbjct: 11 RRQLKKLDEDSLTK--------QPEEVFDVLEKLGEGSYGSVYKAIHKETGQIVAIKQVP 62
Query: 301 LQQQPKKELIINEILVMRENKNPNIVNYLDSYLVGDELWVVMEYLAGGSLTDVVT--ETC 358
++ ++ II EI +M++ +P++V Y SY +LW+VMEY GS++D++
Sbjct: 63 VESDLQE--IIKEISIMQQCDSPHVVKYYGSYFKNTDLWIVMEYCGAGSVSDIIRLRNKT 120
Query: 359 MDEGQIAAVCRECLQALDFLHSNQVIHRDIKSDNILLGMDGSVKLTDFGFCAQITPEQSK 418
+ E +IA + + L+ L++LH + IHRDIK+ NILL +G KL DFG Q+T +K
Sbjct: 121 LTEDEIATILQSTLKGLEYLHFMRKIHRDIKAGNILLNTEGHAKLADFGVAGQLTDTMAK 180
Query: 419 RSTMVGTPYWMAPEVVTRKAYGPKVDIWSLGIMAIEMVEGEPPYLNENPLRALYLIATNG 478
R+T++GTP+WMAPEV+ Y DIWSLGI AIEM EG+PPY + +P+RA+++I TN
Sbjct: 181 RNTVIGTPFWMAPEVIQEIGYNCVADIWSLGITAIEMAEGKPPYADIHPMRAIFMIPTNP 240
Query: 479 TPELQNPERLSAVFRDFLNRCLEMDVDRRGSAKELLQHPFLKLAKPLSSLTPLIIAAKE 537
P + PE S F DF+ +CL ++R +A +LLQHPF++ AK +S L LI A +
Sbjct: 241 PPTFRKPELWSDNFTDFVKQCLVKSPEQRATATQLLQHPFVRSAKGVSILRDLINEAMD 299
Score = 29.6 bits (65), Expect = 7.4
Identities = 19/115 (16%), Positives = 45/115 (39%), Gaps = 3/115 (2%)
Query: 173 EEDEEEEEEEDENEPPPVIAPRPEHTKSIYTRSVVESIASPAVPNKEVTPPSAENANSST 232
++D+EE EEDE + ++ + ++ S + A+ + + + P +
Sbjct: 313 DQDDEENSEEDEMDSGTMVRAVGDEMGTVRVASTMTDGANTMIEHDDTLP---SQLGTMV 369
Query: 233 LYRNTDRQRKKSKMTDEEILEKLRSIVSVGDPKKKYTRFEKIGQGASGTVYTALD 287
+ + + K DE + S + + K+K + G+ G + + D
Sbjct: 370 INAEDEEEEGTMKRRDETMQPAKPSFLEYFEQKEKENQINSFGKSVPGPLKNSSD 424
>gi|15011880 serine/threonine protein kinase MST4 isoform 1 [Homo
sapiens]
Length = 416
Score = 239 bits (611), Expect = 4e-63
Identities = 126/275 (45%), Positives = 179/275 (65%), Gaps = 4/275 (1%)
Query: 260 SVGDPKKKYTRFEKIGQGASGTVYTALDIATGQEVAIKQMNLQQ-QPKKELIINEILVMR 318
++ DP++ +T+ E+IG+G+ G V+ +D T Q VAIK ++L++ + + E I EI V+
Sbjct: 16 NIADPEELFTKLERIGKGSFGEVFKGIDNRTQQVVAIKIIDLEEAEDEIEDIQQEITVLS 75
Query: 319 ENKNPNIVNYLDSYLVGDELWVVMEYLAGGSLTDVVTETCMDEGQIAAVCRECLQALDFL 378
+ + + Y SYL G +LW++MEYL GGS D++ DE QIA + +E L+ LD+L
Sbjct: 76 QCDSSYVTKYYGSYLKGSKLWIIMEYLGGGSALDLLRAGPFDEFQIATMLKEILKGLDYL 135
Query: 379 HSNQVIHRDIKSDNILLGMDGSVKLTDFGFCAQITPEQSKRSTMVGTPYWMAPEVVTRKA 438
HS + IHRDIK+ N+LL G VKL DFG Q+T Q KR+T VGTP+WMAPEV+ + A
Sbjct: 136 HSEKKIHRDIKAANVLLSEQGDVKLADFGVAGQLTDTQIKRNTFVGTPFWMAPEVIQQSA 195
Query: 439 YGPKVDIWSLGIMAIEMVEGEPPYLNENPLRALYLIATNGTPELQNPERLSAVFRDFLNR 498
Y K DIWSLGI AIE+ +GEPP + +P+R L+LI N P L + F++F++
Sbjct: 196 YDSKADIWSLGITAIELAKGEPPNSDMHPMRVLFLIPKNNPPTLVGD--FTKSFKEFIDA 253
Query: 499 CLEMDVDRRGSAKELLQHPFL-KLAKPLSSLTPLI 532
CL D R +AKELL+H F+ K +K S LT LI
Sbjct: 254 CLNKDPSFRPTAKELLKHKFIVKNSKKTSYLTELI 288
>gi|110349738 serine/threonine kinase 24 isoform b [Homo sapiens]
Length = 431
Score = 238 bits (608), Expect = 8e-63
Identities = 126/272 (46%), Positives = 176/272 (64%), Gaps = 4/272 (1%)
Query: 263 DPKKKYTRFEKIGQGASGTVYTALDIATGQEVAIKQMNLQQ-QPKKELIINEILVMRENK 321
DP++ +T+ EKIG+G+ G V+ +D T + VAIK ++L++ + + E I EI V+ +
Sbjct: 19 DPEELFTKLEKIGKGSFGEVFKGIDNRTQKVVAIKIIDLEEAEDEIEDIQQEITVLSQCD 78
Query: 322 NPNIVNYLDSYLVGDELWVVMEYLAGGSLTDVVTETCMDEGQIAAVCRECLQALDFLHSN 381
+P + Y SYL +LW++MEYL GGS D++ +DE QIA + RE L+ LD+LHS
Sbjct: 79 SPYVTKYYGSYLKDTKLWIIMEYLGGGSALDLLEPGPLDETQIATILREILKGLDYLHSE 138
Query: 382 QVIHRDIKSDNILLGMDGSVKLTDFGFCAQITPEQSKRSTMVGTPYWMAPEVVTRKAYGP 441
+ IHRDIK+ N+LL G VKL DFG Q+T Q KR+T VGTP+WMAPEV+ + AY
Sbjct: 139 KKIHRDIKAANVLLSEHGEVKLADFGVAGQLTDTQIKRNTFVGTPFWMAPEVIKQSAYDS 198
Query: 442 KVDIWSLGIMAIEMVEGEPPYLNENPLRALYLIATNGTPELQNPERLSAVFRDFLNRCLE 501
K DIWSLGI AIE+ GEPP+ +P++ L+LI N P L+ S ++F+ CL
Sbjct: 199 KADIWSLGITAIELARGEPPHSELHPMKVLFLIPKNNPPTLEG--NYSKPLKEFVEACLN 256
Query: 502 MDVDRRGSAKELLQHPF-LKLAKPLSSLTPLI 532
+ R +AKELL+H F L+ AK S LT LI
Sbjct: 257 KEPSFRPTAKELLKHKFILRNAKKTSYLTELI 288
>gi|20070158 serine/threonine kinase 24 isoform a [Homo sapiens]
Length = 443
Score = 238 bits (608), Expect = 8e-63
Identities = 126/272 (46%), Positives = 176/272 (64%), Gaps = 4/272 (1%)
Query: 263 DPKKKYTRFEKIGQGASGTVYTALDIATGQEVAIKQMNLQQ-QPKKELIINEILVMRENK 321
DP++ +T+ EKIG+G+ G V+ +D T + VAIK ++L++ + + E I EI V+ +
Sbjct: 31 DPEELFTKLEKIGKGSFGEVFKGIDNRTQKVVAIKIIDLEEAEDEIEDIQQEITVLSQCD 90
Query: 322 NPNIVNYLDSYLVGDELWVVMEYLAGGSLTDVVTETCMDEGQIAAVCRECLQALDFLHSN 381
+P + Y SYL +LW++MEYL GGS D++ +DE QIA + RE L+ LD+LHS
Sbjct: 91 SPYVTKYYGSYLKDTKLWIIMEYLGGGSALDLLEPGPLDETQIATILREILKGLDYLHSE 150
Query: 382 QVIHRDIKSDNILLGMDGSVKLTDFGFCAQITPEQSKRSTMVGTPYWMAPEVVTRKAYGP 441
+ IHRDIK+ N+LL G VKL DFG Q+T Q KR+T VGTP+WMAPEV+ + AY
Sbjct: 151 KKIHRDIKAANVLLSEHGEVKLADFGVAGQLTDTQIKRNTFVGTPFWMAPEVIKQSAYDS 210
Query: 442 KVDIWSLGIMAIEMVEGEPPYLNENPLRALYLIATNGTPELQNPERLSAVFRDFLNRCLE 501
K DIWSLGI AIE+ GEPP+ +P++ L+LI N P L+ S ++F+ CL
Sbjct: 211 KADIWSLGITAIELARGEPPHSELHPMKVLFLIPKNNPPTLEG--NYSKPLKEFVEACLN 268
Query: 502 MDVDRRGSAKELLQHPF-LKLAKPLSSLTPLI 532
+ R +AKELL+H F L+ AK S LT LI
Sbjct: 269 KEPSFRPTAKELLKHKFILRNAKKTSYLTELI 300
>gi|21361358 serine/threonine kinase 25 [Homo sapiens]
Length = 426
Score = 236 bits (602), Expect = 4e-62
Identities = 125/272 (45%), Positives = 176/272 (64%), Gaps = 4/272 (1%)
Query: 263 DPKKKYTRFEKIGQGASGTVYTALDIATGQEVAIKQMNLQQ-QPKKELIINEILVMRENK 321
DP++ +T+ ++IG+G+ G VY +D T + VAIK ++L++ + + E I EI V+ +
Sbjct: 15 DPEELFTKLDRIGKGSFGEVYKGIDNHTKEVVAIKIIDLEEAEDEIEDIQQEITVLSQCD 74
Query: 322 NPNIVNYLDSYLVGDELWVVMEYLAGGSLTDVVTETCMDEGQIAAVCRECLQALDFLHSN 381
+P I Y SYL +LW++MEYL GGS D++ ++E IA + RE L+ LD+LHS
Sbjct: 75 SPYITRYFGSYLKSTKLWIIMEYLGGGSALDLLKPGPLEETYIATILREILKGLDYLHSE 134
Query: 382 QVIHRDIKSDNILLGMDGSVKLTDFGFCAQITPEQSKRSTMVGTPYWMAPEVVTRKAYGP 441
+ IHRDIK+ N+LL G VKL DFG Q+T Q KR+T VGTP+WMAPEV+ + AY
Sbjct: 135 RKIHRDIKAANVLLSEQGDVKLADFGVAGQLTDTQIKRNTFVGTPFWMAPEVIKQSAYDF 194
Query: 442 KVDIWSLGIMAIEMVEGEPPYLNENPLRALYLIATNGTPELQNPERLSAVFRDFLNRCLE 501
K DIWSLGI AIE+ +GEPP + +P+R L+LI N P L+ S F++F+ CL
Sbjct: 195 KADIWSLGITAIELAKGEPPNSDLHPMRVLFLIPKNSPPTLEGQH--SKPFKEFVEACLN 252
Query: 502 MDVDRRGSAKELLQHPFL-KLAKPLSSLTPLI 532
D R +AKELL+H F+ + K S LT LI
Sbjct: 253 KDPRFRPTAKELLKHKFITRYTKKTSFLTELI 284
>gi|22035600 mitogen-activated protein kinase kinase kinase kinase 2
[Homo sapiens]
Length = 820
Score = 214 bits (545), Expect = 2e-55
Identities = 118/285 (41%), Positives = 171/285 (60%), Gaps = 6/285 (2%)
Query: 259 VSVGDPKKKYTRFEKIGQGASGTVYTALDIATGQEVAIKQMNLQQQPKKELIINEILVMR 318
VS+ DP+ ++ +++G G G VY A D T + A+K + L + EI ++R
Sbjct: 7 VSLQDPRDRFELLQRVGAGTYGDVYKARDTVTSELAAVKIVKLDPGDDISSLQQEITILR 66
Query: 319 ENKNPNIVNYLDSYLVGDELWVVMEYLAGGSLTDVVTETC-MDEGQIAAVCRECLQALDF 377
E ++PN+V Y+ SYL D LW+ ME+ GGSL ++ T ++E QIA VCRE L+ L
Sbjct: 67 ECRHPNVVAYIGSYLRNDRLWICMEFCGGGSLQEIYHATGPLEERQIAYVCREALKGLHH 126
Query: 378 LHSNQVIHRDIKSDNILLGMDGSVKLTDFGFCAQITPEQSKRSTMVGTPYWMAPEV--VT 435
LHS IHRDIK N+LL + G VKL DFG ++T +KR + +GTPYWMAPEV V
Sbjct: 127 LHSQGKIHRDIKGANLLLTLQGDVKLADFGVSGELTASVAKRRSFIGTPYWMAPEVAAVE 186
Query: 436 RK-AYGPKVDIWSLGIMAIEMVEGEPPYLNENPLRALYLIATNG--TPELQNPERLSAVF 492
RK Y D+W+LGI AIE+ E +PP + +P+RAL L++ + P+L++ R + F
Sbjct: 187 RKGGYNELCDVWALGITAIELGELQPPLFHLHPMRALMLMSKSSFQPPKLRDKTRWTQNF 246
Query: 493 RDFLNRCLEMDVDRRGSAKELLQHPFLKLAKPLSSLTPLIIAAKE 537
FL L + +R +A++LLQHPF P + LT L+ A +
Sbjct: 247 HHFLKLALTKNPKKRPTAEKLLQHPFTTQQLPRALLTQLLDKASD 291
>gi|41281453 serine/threonine kinase 2 [Homo sapiens]
Length = 1235
Score = 213 bits (541), Expect = 5e-55
Identities = 117/297 (39%), Positives = 176/297 (59%), Gaps = 9/297 (3%)
Query: 241 RKKSKMTDEEILEKLRSIVSVGDPKKKYTRFEKIGQGASGTVYTALDIATGQEVAIKQMN 300
RK K+ E+ ++ + +P+ + ++G GA G VY A + T A K ++
Sbjct: 7 RKIFKLGSEKKKKQYEHVKRDLNPEDFWEIIGELGDGAFGKVYKAQNKETSVLAAAKVID 66
Query: 301 LQQQPKKELIINEILVMRENKNPNIVNYLDSYLVGDELWVVMEYLAGGSLTDVVTET--C 358
+ + + E + EI ++ +PNIV LD++ + LW+++E+ AGG++ V+ E
Sbjct: 67 TKSEEELEDYMVEIDILASCDHPNIVKLLDAFYYENNLWILIEFCAGGAVDAVMLELERP 126
Query: 359 MDEGQIAAVCRECLQALDFLHSNQVIHRDIKSDNILLGMDGSVKLTDFGFCAQITPEQSK 418
+ E QI VC++ L AL++LH N++IHRD+K+ NIL +DG +KL DFG A+ T +
Sbjct: 127 LTESQIQVVCKQTLDALNYLHDNKIIHRDLKAGNILFTLDGDIKLADFGVSAKNTRTIQR 186
Query: 419 RSTMVGTPYWMAPEVV-----TRKAYGPKVDIWSLGIMAIEMVEGEPPYLNENPLRALYL 473
R + +GTPYWMAPEVV + Y K D+WSLGI IEM E EPP+ NP+R L
Sbjct: 187 RDSFIGTPYWMAPEVVMCETSKDRPYDYKADVWSLGITLIEMAEIEPPHHELNPMRVLLK 246
Query: 474 IATNGTPELQNPERLSAVFRDFLNRCLEMDVDRRGSAKELLQHPFLKL--AKPLSSL 528
IA + P L P R S+ F+DFL +CLE +VD R + +LLQHPF+ + KP+ L
Sbjct: 247 IAKSEPPTLAQPSRWSSNFKDFLKKCLEKNVDARWTTSQLLQHPFVTVDSNKPIREL 303
Score = 29.6 bits (65), Expect = 7.4
Identities = 26/111 (23%), Positives = 46/111 (41%), Gaps = 13/111 (11%)
Query: 167 APPVSEEEDEEEEEEEDENEPP------------PVIAPRPEHTKSIYTRSVVESIASPA 214
A V+++ DE+ E+ N+ P++ P TK + + +VE
Sbjct: 554 AADVAQKVDEDSAEDTQSNDGKEVVEVGQKLINKPMVGPEAGGTKEVPIKEIVEMNEIEE 613
Query: 215 VPNKEVTPPSAENANSSTLYRNTDRQRKKSKMTDEEILEKLRSIVSVGDPK 265
NKE S+EN T + ++ + E +E +RS+V+ D K
Sbjct: 614 GKNKEQAINSSENIMDINEEPGTTEGEEITESSSTEEME-VRSVVADTDQK 663
>gi|15451902 mitogen-activated protein kinase kinase kinase kinase 3
[Homo sapiens]
Length = 894
Score = 206 bits (525), Expect = 3e-53
Identities = 115/263 (43%), Positives = 166/263 (63%), Gaps = 6/263 (2%)
Query: 263 DPKKKYTRFEKIGQGASGTVYTALDIATGQEVAIKQMNLQQQPKKELIINEILVMRENKN 322
+P++ + ++IG G G VY A ++ TG+ AIK + L+ ++ EI++M++ K+
Sbjct: 11 NPQEDFELIQRIGSGTYGDVYKARNVNTGELAAIKVIKLEPGEDFAVVQQEIIMMKDCKH 70
Query: 323 PNIVNYLDSYLVGDELWVVMEYLAGGSLTDVVTETC-MDEGQIAAVCRECLQALDFLHSN 381
PNIV Y SYL D+LW+ ME+ GGSL D+ T + E QIA V RE LQ L +LHS
Sbjct: 71 PNIVAYFGSYLRRDKLWICMEFCGGGSLQDIYHVTGPLSELQIAYVSRETLQGLYYLHSK 130
Query: 382 QVIHRDIKSDNILLGMDGSVKLTDFGFCAQITPEQSKRSTMVGTPYWMAPEV--VTRK-A 438
+HRDIK NILL +G VKL DFG AQIT +KR + +GTPYWMAPEV V RK
Sbjct: 131 GKMHRDIKGANILLTDNGHVKLADFGVSAQITATIAKRKSFIGTPYWMAPEVAAVERKGG 190
Query: 439 YGPKVDIWSLGIMAIEMVEGEPPYLNENPLRALYLIATNG--TPELQNPERLSAVFRDFL 496
Y D+W++GI AIE+ E +PP + +P+RAL+L+ + P+L++ + S F F+
Sbjct: 191 YNQLCDLWAVGITAIELAELQPPMFDLHPMRALFLMTKSNFQPPKLKDKMKWSNSFHHFV 250
Query: 497 NRCLEMDVDRRGSAKELLQHPFL 519
L + +R +A++LLQHPF+
Sbjct: 251 KMALTKNPKKRPTAEKLLQHPFV 273
>gi|145275208 myosin IIIA [Homo sapiens]
Length = 1616
Score = 203 bits (517), Expect = 3e-52
Identities = 109/272 (40%), Positives = 161/272 (59%), Gaps = 15/272 (5%)
Query: 263 DPKKKYTRFEKIGQGASGTVYTALDIATGQEVAIKQMNLQQQPKKELIINEILVMRENKN 322
DP + E IG+G G V+ L+ GQ+ A+K ++ +E+ ++ + +
Sbjct: 16 DPSDTWEITETIGKGTYGKVFKVLNKKNGQKAAVKILDPIHDIDEEIEAEYNILKALSDH 75
Query: 323 PNIVNYLDSYLV-----GDELWVVMEYLAGGSLTDVVTETC-----MDEGQIAAVCRECL 372
PN+V + Y GD+LW+V+E +GGS+TD+V M E IA + E L
Sbjct: 76 PNVVRFYGIYFKKDKVNGDKLWLVLELCSGGSVTDLVKGFLKRGERMSEPLIAYILHEAL 135
Query: 373 QALDFLHSNQVIHRDIKSDNILLGMDGSVKLTDFGFCAQITPEQSKRSTMVGTPYWMAPE 432
L LH+N+ IHRD+K +NILL +G VKL DFG AQ+T + +R+T VGTP+WMAPE
Sbjct: 136 MGLQHLHNNKTIHRDVKGNNILLTTEGGVKLVDFGVSAQLTSTRHRRNTSVGTPFWMAPE 195
Query: 433 VVTRK-----AYGPKVDIWSLGIMAIEMVEGEPPYLNENPLRALYLIATNGTPELQNPER 487
V+ + Y + D WSLGI AIE+ +G+PP + +P+RAL+ I N P+L+ PE
Sbjct: 196 VIACEQQLDTTYDARCDTWSLGITAIELGDGDPPLADLHPMRALFKIPRNPPPKLRQPEL 255
Query: 488 LSAVFRDFLNRCLEMDVDRRGSAKELLQHPFL 519
SA F DF+++CL D ++R + ELLQH F+
Sbjct: 256 WSAEFNDFISKCLTKDYEKRPTVSELLQHKFI 287
>gi|45439370 TAO kinase 1 [Homo sapiens]
Length = 1001
Score = 202 bits (515), Expect = 5e-52
Identities = 122/286 (42%), Positives = 170/286 (59%), Gaps = 14/286 (4%)
Query: 263 DPKKKYTRFEKIGQGASGTVYTALDIATGQEVAIKQMNL---QQQPKKELIINEILVMRE 319
DP+K +T +IG G+ G VY A D+ T + VAIK+M+ Q K + II E+ ++
Sbjct: 23 DPEKLFTDLREIGHGSFGAVYFARDVRTNEVVAIKKMSYSGKQSTEKWQDIIKEVKFLQR 82
Query: 320 NKNPNIVNYLDSYLVGDELWVVMEYLAGGSLTDV--VTETCMDEGQIAAVCRECLQALDF 377
K+PN + Y YL W+VMEY G S +D+ V + + E +IAA+ LQ L +
Sbjct: 83 IKHPNSIEYKGCYLREHTAWLVMEYCLG-SASDLLEVHKKPLQEVEIAAITHGALQGLAY 141
Query: 378 LHSNQVIHRDIKSDNILLGMDGSVKLTDFGFCAQITPEQSKRSTMVGTPYWMAPEVV--- 434
LHS+ +IHRDIK+ NILL G VKL DFG + +P S VGTPYWMAPEV+
Sbjct: 142 LHSHTMIHRDIKAGNILLTEPGQVKLADFGSASMASPANS----FVGTPYWMAPEVILAM 197
Query: 435 TRKAYGPKVDIWSLGIMAIEMVEGEPPYLNENPLRALYLIATNGTPELQNPERLSAVFRD 494
Y KVD+WSLGI IE+ E +PP N N + ALY IA N +P LQ+ E S FR+
Sbjct: 198 DEGQYDGKVDVWSLGITCIELAERKPPLFNMNAMSALYHIAQNESPTLQSNE-WSDYFRN 256
Query: 495 FLNRCLEMDVDRRGSAKELLQHPFLKLAKPLSSLTPLIIAAKEAIK 540
F++ CL+ R +++ELL+H F+ +P + L LI K+A++
Sbjct: 257 FVDSCLQKIPQDRPTSEELLKHIFVLRERPETVLIDLIQRTKDAVR 302
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.311 0.130 0.368
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 23,331,976
Number of Sequences: 37866
Number of extensions: 1199506
Number of successful extensions: 18775
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 982
Number of HSP's successfully gapped in prelim test: 292
Number of HSP's that attempted gapping in prelim test: 10787
Number of HSP's gapped (non-prelim): 4345
length of query: 544
length of database: 18,247,518
effective HSP length: 107
effective length of query: 437
effective length of database: 14,195,856
effective search space: 6203589072
effective search space used: 6203589072
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.