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Search of human proteins with 4505415
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4505415 NAD(P)H menadione oxidoreductase 1, dioxin-inducible
isoform a [Homo sapiens]
(274 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4505415 NAD(P)H menadione oxidoreductase 1, dioxin-inducible ... 557 e-159
gi|70995396 NAD(P)H menadione oxidoreductase 1, dioxin-inducible... 473 e-133
gi|70995422 NAD(P)H menadione oxidoreductase 1, dioxin-inducible... 456 e-128
gi|156564357 NAD(P)H dehydrogenase, quinone 2 [Homo sapiens] 220 1e-57
gi|21361423 solute carrier family 39 (zinc transporter), member ... 30 1.7
gi|116256363 transmembrane protease, serine 13 [Homo sapiens] 30 1.7
gi|74048554 cancer susceptibility candidate 5 isoform 2 [Homo sa... 29 3.9
gi|74048514 cancer susceptibility candidate 5 isoform 1 [Homo sa... 29 3.9
gi|4557303 aldehyde dehydrogenase 3A2 isoform 2 [Homo sapiens] 28 6.6
gi|73466520 aldehyde dehydrogenase 3A2 isoform 1 [Homo sapiens] 28 6.6
gi|7662126 signal-induced proliferation-associated 1 like 1 [Hom... 28 8.6
gi|170932492 transmembrane protease, serine 5 [Homo sapiens] 28 8.6
>gi|4505415 NAD(P)H menadione oxidoreductase 1, dioxin-inducible
isoform a [Homo sapiens]
Length = 274
Score = 557 bits (1436), Expect = e-159
Identities = 274/274 (100%), Positives = 274/274 (100%)
Query: 1 MVGRRALIVLAHSERTSFNYAMKEAAAAALKKKGWEVVESDLYAMNFNPIISRKDITGKL 60
MVGRRALIVLAHSERTSFNYAMKEAAAAALKKKGWEVVESDLYAMNFNPIISRKDITGKL
Sbjct: 1 MVGRRALIVLAHSERTSFNYAMKEAAAAALKKKGWEVVESDLYAMNFNPIISRKDITGKL 60
Query: 61 KDPANFQYPAESVLAYKEGHLSPDIVAEQKKLEAADLVIFQFPLQWFGVPAILKGWFERV 120
KDPANFQYPAESVLAYKEGHLSPDIVAEQKKLEAADLVIFQFPLQWFGVPAILKGWFERV
Sbjct: 61 KDPANFQYPAESVLAYKEGHLSPDIVAEQKKLEAADLVIFQFPLQWFGVPAILKGWFERV 120
Query: 121 FIGEFAYTYAAMYDKGPFRSKKAVLSITTGGSGSMYSLQGIHGDMNVILWPIQSGILHFC 180
FIGEFAYTYAAMYDKGPFRSKKAVLSITTGGSGSMYSLQGIHGDMNVILWPIQSGILHFC
Sbjct: 121 FIGEFAYTYAAMYDKGPFRSKKAVLSITTGGSGSMYSLQGIHGDMNVILWPIQSGILHFC 180
Query: 181 GFQVLEPQLTYSIGHTPADARIQILEGWKKRLENIWDETPLYFAPSSLFDLNFQAGFLMK 240
GFQVLEPQLTYSIGHTPADARIQILEGWKKRLENIWDETPLYFAPSSLFDLNFQAGFLMK
Sbjct: 181 GFQVLEPQLTYSIGHTPADARIQILEGWKKRLENIWDETPLYFAPSSLFDLNFQAGFLMK 240
Query: 241 KEVQDEEKNKKFGLSVGHHLGKSIPTDNQIKARK 274
KEVQDEEKNKKFGLSVGHHLGKSIPTDNQIKARK
Sbjct: 241 KEVQDEEKNKKFGLSVGHHLGKSIPTDNQIKARK 274
>gi|70995396 NAD(P)H menadione oxidoreductase 1, dioxin-inducible
isoform b [Homo sapiens]
Length = 240
Score = 473 bits (1216), Expect = e-133
Identities = 240/274 (87%), Positives = 240/274 (87%), Gaps = 34/274 (12%)
Query: 1 MVGRRALIVLAHSERTSFNYAMKEAAAAALKKKGWEVVESDLYAMNFNPIISRKDITGKL 60
MVGRRALIVLAHSERTSFNYAMKEAAAAALKKKGWEVVESDLYAMNFNPIISRKDITGKL
Sbjct: 1 MVGRRALIVLAHSERTSFNYAMKEAAAAALKKKGWEVVESDLYAMNFNPIISRKDITGKL 60
Query: 61 KDPANFQYPAESVLAYKEGHLSPDIVAEQKKLEAADLVIFQFPLQWFGVPAILKGWFERV 120
KDPANFQYPAESVLAYKEGHLSPDIVAEQKKLEAADLVIFQFPLQWFGVPAILKGWFERV
Sbjct: 61 KDPANFQYPAESVLAYKEGHLSPDIVAEQKKLEAADLVIFQFPLQWFGVPAILKGWFERV 120
Query: 121 FIGEFAYTYAAMYDKGPFRSKKAVLSITTGGSGSMYSLQGIHGDMNVILWPIQSGILHFC 180
FIGEFAYTYAAMYDKGPFR SGILHFC
Sbjct: 121 FIGEFAYTYAAMYDKGPFR----------------------------------SGILHFC 146
Query: 181 GFQVLEPQLTYSIGHTPADARIQILEGWKKRLENIWDETPLYFAPSSLFDLNFQAGFLMK 240
GFQVLEPQLTYSIGHTPADARIQILEGWKKRLENIWDETPLYFAPSSLFDLNFQAGFLMK
Sbjct: 147 GFQVLEPQLTYSIGHTPADARIQILEGWKKRLENIWDETPLYFAPSSLFDLNFQAGFLMK 206
Query: 241 KEVQDEEKNKKFGLSVGHHLGKSIPTDNQIKARK 274
KEVQDEEKNKKFGLSVGHHLGKSIPTDNQIKARK
Sbjct: 207 KEVQDEEKNKKFGLSVGHHLGKSIPTDNQIKARK 240
>gi|70995422 NAD(P)H menadione oxidoreductase 1, dioxin-inducible
isoform c [Homo sapiens]
Length = 236
Score = 456 bits (1172), Expect = e-128
Identities = 236/274 (86%), Positives = 236/274 (86%), Gaps = 38/274 (13%)
Query: 1 MVGRRALIVLAHSERTSFNYAMKEAAAAALKKKGWEVVESDLYAMNFNPIISRKDITGKL 60
MVGRRALIVLAHSERTSFNYAMKEAAAAALKKKGWEVVESDLYAMNFNPIISRKDITGKL
Sbjct: 1 MVGRRALIVLAHSERTSFNYAMKEAAAAALKKKGWEVVESDLYAMNFNPIISRKDITGKL 60
Query: 61 KDPANFQYPAESVLAYKEGHLSPDIVAEQKKLEAADLVIFQFPLQWFGVPAILKGWFERV 120
KDPANFQYPAESVLAYKEGHLSPDIVAEQKKLEAADLVIFQ
Sbjct: 61 KDPANFQYPAESVLAYKEGHLSPDIVAEQKKLEAADLVIFQ------------------- 101
Query: 121 FIGEFAYTYAAMYDKGPFRSKKAVLSITTGGSGSMYSLQGIHGDMNVILWPIQSGILHFC 180
SKKAVLSITTGGSGSMYSLQGIHGDMNVILWPIQSGILHFC
Sbjct: 102 -------------------SKKAVLSITTGGSGSMYSLQGIHGDMNVILWPIQSGILHFC 142
Query: 181 GFQVLEPQLTYSIGHTPADARIQILEGWKKRLENIWDETPLYFAPSSLFDLNFQAGFLMK 240
GFQVLEPQLTYSIGHTPADARIQILEGWKKRLENIWDETPLYFAPSSLFDLNFQAGFLMK
Sbjct: 143 GFQVLEPQLTYSIGHTPADARIQILEGWKKRLENIWDETPLYFAPSSLFDLNFQAGFLMK 202
Query: 241 KEVQDEEKNKKFGLSVGHHLGKSIPTDNQIKARK 274
KEVQDEEKNKKFGLSVGHHLGKSIPTDNQIKARK
Sbjct: 203 KEVQDEEKNKKFGLSVGHHLGKSIPTDNQIKARK 236
>gi|156564357 NAD(P)H dehydrogenase, quinone 2 [Homo sapiens]
Length = 231
Score = 220 bits (560), Expect = 1e-57
Identities = 107/221 (48%), Positives = 140/221 (63%)
Query: 1 MVGRRALIVLAHSERTSFNYAMKEAAAAALKKKGWEVVESDLYAMNFNPIISRKDITGKL 60
M G++ LIV AH E SFN ++K A L ++G V SDLYAMN P + KDITG L
Sbjct: 1 MAGKKVLIVYAHQEPKSFNGSLKNVAVDELSRQGCTVTVSDLYAMNLEPRATDKDITGTL 60
Query: 61 KDPANFQYPAESVLAYKEGHLSPDIVAEQKKLEAADLVIFQFPLQWFGVPAILKGWFERV 120
+P F Y E+ AYK+ L+ DI EQKK+ ADLVIFQFPL WF VPAILKGW +RV
Sbjct: 61 SNPEVFNYGVETHEAYKQRSLASDITDEQKKVREADLVIFQFPLYWFSVPAILKGWMDRV 120
Query: 121 FIGEFAYTYAAMYDKGPFRSKKAVLSITTGGSGSMYSLQGIHGDMNVILWPIQSGILHFC 180
FA+ YD G + K A+LS+TTGG+ MY+ G++GD LWP+Q G LHFC
Sbjct: 121 LCQGFAFDIPGFYDSGLLQGKLALLSVTTGGTAEMYTKTGVNGDSRYFLWPLQHGTLHFC 180
Query: 181 GFQVLEPQLTYSIGHTPADARIQILEGWKKRLENIWDETPL 221
GF+VL PQ++++ + R ++ W +RL+ IW E P+
Sbjct: 181 GFKVLAPQISFAPEIASEEERKGMVAAWSQRLQTIWKEEPI 221
>gi|21361423 solute carrier family 39 (zinc transporter), member 1
[Homo sapiens]
Length = 324
Score = 30.4 bits (67), Expect = 1.7
Identities = 22/81 (27%), Positives = 33/81 (40%), Gaps = 3/81 (3%)
Query: 81 LSPDIVAEQKKLEAADLVIFQFPLQWFGVPAILKGWFERVFIGEFAYTYAAMYDKGPFRS 140
L PD +A + AA V QFPLQ F + G+F + + + Y P
Sbjct: 88 LLPDYLAAIDEALAALHVTLQFPLQEF---ILAMGFFLVLVMEQITLAYKEQSGPSPLEE 144
Query: 141 KKAVLSITTGGSGSMYSLQGI 161
+A+L GG + G+
Sbjct: 145 TRALLGTVNGGPQHWHDGPGV 165
>gi|116256363 transmembrane protease, serine 13 [Homo sapiens]
Length = 567
Score = 30.4 bits (67), Expect = 1.7
Identities = 15/44 (34%), Positives = 21/44 (47%), Gaps = 4/44 (9%)
Query: 170 WPIQS----GILHFCGFQVLEPQLTYSIGHTPADARIQILEGWK 209
WP Q G H CG +++ Q + H R ++LEGWK
Sbjct: 337 WPWQVSLHFGTTHICGGTLIDAQWVLTAAHCFFVTREKVLEGWK 380
>gi|74048554 cancer susceptibility candidate 5 isoform 2 [Homo
sapiens]
Length = 2316
Score = 29.3 bits (64), Expect = 3.9
Identities = 12/22 (54%), Positives = 15/22 (68%)
Query: 247 EKNKKFGLSVGHHLGKSIPTDN 268
E+N KFG+ G +LG S P DN
Sbjct: 1184 EENPKFGIGKGKNLGVSFPKDN 1205
>gi|74048514 cancer susceptibility candidate 5 isoform 1 [Homo
sapiens]
Length = 2342
Score = 29.3 bits (64), Expect = 3.9
Identities = 12/22 (54%), Positives = 15/22 (68%)
Query: 247 EKNKKFGLSVGHHLGKSIPTDN 268
E+N KFG+ G +LG S P DN
Sbjct: 1210 EENPKFGIGKGKNLGVSFPKDN 1231
>gi|4557303 aldehyde dehydrogenase 3A2 isoform 2 [Homo sapiens]
Length = 485
Score = 28.5 bits (62), Expect = 6.6
Identities = 20/68 (29%), Positives = 29/68 (42%), Gaps = 1/68 (1%)
Query: 166 NVILWPIQSGILHFCGFQVLE-PQLTYSIGHTPADARIQILEGWKKRLENIWDETPLYFA 224
N I+W I+ + F G + E P I + +LEG K DE Y A
Sbjct: 255 NQIVWKIKETVKEFYGENIKESPDYERIINLRHFKRILSLLEGQKIAFGGETDEATRYIA 314
Query: 225 PSSLFDLN 232
P+ L D++
Sbjct: 315 PTVLTDVD 322
>gi|73466520 aldehyde dehydrogenase 3A2 isoform 1 [Homo sapiens]
Length = 508
Score = 28.5 bits (62), Expect = 6.6
Identities = 20/68 (29%), Positives = 29/68 (42%), Gaps = 1/68 (1%)
Query: 166 NVILWPIQSGILHFCGFQVLE-PQLTYSIGHTPADARIQILEGWKKRLENIWDETPLYFA 224
N I+W I+ + F G + E P I + +LEG K DE Y A
Sbjct: 255 NQIVWKIKETVKEFYGENIKESPDYERIINLRHFKRILSLLEGQKIAFGGETDEATRYIA 314
Query: 225 PSSLFDLN 232
P+ L D++
Sbjct: 315 PTVLTDVD 322
>gi|7662126 signal-induced proliferation-associated 1 like 1 [Homo
sapiens]
Length = 1804
Score = 28.1 bits (61), Expect = 8.6
Identities = 14/33 (42%), Positives = 20/33 (60%)
Query: 134 DKGPFRSKKAVLSITTGGSGSMYSLQGIHGDMN 166
D+GP +K + IT GG GS +SL I G ++
Sbjct: 235 DRGPTPTKLSDFLITGGGKGSGFSLDVIDGPIS 267
>gi|170932492 transmembrane protease, serine 5 [Homo sapiens]
Length = 457
Score = 28.1 bits (61), Expect = 8.6
Identities = 14/44 (31%), Positives = 19/44 (43%), Gaps = 4/44 (9%)
Query: 170 WPIQS----GILHFCGFQVLEPQLTYSIGHTPADARIQILEGWK 209
WP Q+ G H CG VL P+ + H R+ L W+
Sbjct: 229 WPWQASVALGFRHTCGGSVLAPRWVVTAAHCMHSFRLARLSSWR 272
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.320 0.137 0.414
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 10,121,849
Number of Sequences: 37866
Number of extensions: 436251
Number of successful extensions: 798
Number of sequences better than 10.0: 12
Number of HSP's better than 10.0 without gapping: 8
Number of HSP's successfully gapped in prelim test: 4
Number of HSP's that attempted gapping in prelim test: 788
Number of HSP's gapped (non-prelim): 14
length of query: 274
length of database: 18,247,518
effective HSP length: 101
effective length of query: 173
effective length of database: 14,423,052
effective search space: 2495187996
effective search space used: 2495187996
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.