Guide to the Human Genome
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Search of human proteins with 4505357

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|4505357 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex,
4, 9kDa [Homo sapiens]
         (81 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|4505357 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4...   174   1e-44
gi|239753639 PREDICTED: similar to hCG2040339 [Homo sapiens]          138   1e-33
gi|239748188 PREDICTED: similar to hCG2040339 [Homo sapiens]          138   1e-33
gi|239742082 PREDICTED: hypothetical protein XP_002342432 [Homo ...   138   1e-33
gi|239755555 PREDICTED: similar to NADH dehydrogenase (ubiquinon...   120   3e-28
gi|239750055 PREDICTED: hypothetical protein XP_002347281 [Homo ...   120   3e-28
gi|239744362 PREDICTED: hypothetical protein XP_002343134 [Homo ...   120   3e-28
gi|10047138 NADH:ubiquinone oxidoreductase MLRQ subunit homolog ...   110   3e-25
gi|14165280 normal mucosa of esophagus specific 1 [Homo sapiens]       42   1e-04
gi|37694067 normal mucosa of esophagus specific 1 [Homo sapiens]       42   1e-04
gi|55741655 anoctamin 8 [Homo sapiens]                                 27   2.7  
gi|42542383 solute carrier family 28, member 1 isoform 2 [Homo s...    27   3.5  
gi|92859871 SMAD family member 6 isoform 1 [Homo sapiens]              26   7.8  

>gi|4505357 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4,
          9kDa [Homo sapiens]
          Length = 81

 Score =  174 bits (442), Expect = 1e-44
 Identities = 81/81 (100%), Positives = 81/81 (100%)

Query: 1  MLRQIIGQAKKHPSLIPLFVFIGTGATGATLYLLRLALFNPDVCWDRNNPEPWNKLGPND 60
          MLRQIIGQAKKHPSLIPLFVFIGTGATGATLYLLRLALFNPDVCWDRNNPEPWNKLGPND
Sbjct: 1  MLRQIIGQAKKHPSLIPLFVFIGTGATGATLYLLRLALFNPDVCWDRNNPEPWNKLGPND 60

Query: 61 QYKFYSVNVDYSKLKKERPDF 81
          QYKFYSVNVDYSKLKKERPDF
Sbjct: 61 QYKFYSVNVDYSKLKKERPDF 81


>gi|239753639 PREDICTED: similar to hCG2040339 [Homo sapiens]
          Length = 100

 Score =  138 bits (347), Expect = 1e-33
 Identities = 68/82 (82%), Positives = 70/82 (85%), Gaps = 1/82 (1%)

Query: 1   MLRQIIGQAKKHPSLIPLFVFIGTGATGATLYLLRLALFNPDVCWDR-NNPEPWNKLGPN 59
           +L QII Q KKHPSL+PLFVFIG G TGA LYLL LALFNPDV WDR NN EPWNKL PN
Sbjct: 19  ILCQIISQVKKHPSLMPLFVFIGVGDTGAALYLLFLALFNPDVNWDRKNNSEPWNKLDPN 78

Query: 60  DQYKFYSVNVDYSKLKKERPDF 81
           DQYKFYSVNVDYSKLKKE PDF
Sbjct: 79  DQYKFYSVNVDYSKLKKEGPDF 100


>gi|239748188 PREDICTED: similar to hCG2040339 [Homo sapiens]
          Length = 100

 Score =  138 bits (347), Expect = 1e-33
 Identities = 68/82 (82%), Positives = 70/82 (85%), Gaps = 1/82 (1%)

Query: 1   MLRQIIGQAKKHPSLIPLFVFIGTGATGATLYLLRLALFNPDVCWDR-NNPEPWNKLGPN 59
           +L QII Q KKHPSL+PLFVFIG G TGA LYLL LALFNPDV WDR NN EPWNKL PN
Sbjct: 19  ILCQIISQVKKHPSLMPLFVFIGVGDTGAALYLLFLALFNPDVNWDRKNNSEPWNKLDPN 78

Query: 60  DQYKFYSVNVDYSKLKKERPDF 81
           DQYKFYSVNVDYSKLKKE PDF
Sbjct: 79  DQYKFYSVNVDYSKLKKEGPDF 100


>gi|239742082 PREDICTED: hypothetical protein XP_002342432 [Homo
           sapiens]
          Length = 100

 Score =  138 bits (347), Expect = 1e-33
 Identities = 68/82 (82%), Positives = 70/82 (85%), Gaps = 1/82 (1%)

Query: 1   MLRQIIGQAKKHPSLIPLFVFIGTGATGATLYLLRLALFNPDVCWDR-NNPEPWNKLGPN 59
           +L QII Q KKHPSL+PLFVFIG G TGA LYLL LALFNPDV WDR NN EPWNKL PN
Sbjct: 19  ILCQIISQVKKHPSLMPLFVFIGVGDTGAALYLLFLALFNPDVNWDRKNNSEPWNKLDPN 78

Query: 60  DQYKFYSVNVDYSKLKKERPDF 81
           DQYKFYSVNVDYSKLKKE PDF
Sbjct: 79  DQYKFYSVNVDYSKLKKEGPDF 100


>gi|239755555 PREDICTED: similar to NADH dehydrogenase
          (ubiquinone) 1 alpha subcomplex, 4 [Homo sapiens]
          Length = 82

 Score =  120 bits (300), Expect = 3e-28
 Identities = 58/82 (70%), Positives = 64/82 (78%), Gaps = 1/82 (1%)

Query: 1  MLRQIIGQAKKHPSLIPLFVFIGTGATGATLYLLRLALFNPDVCWDRNN-PEPWNKLGPN 59
          M  Q + Q KK+PSLI  F+FIG G+TGA  Y+L LA F+PDV W RNN PEPWNKL PN
Sbjct: 1  MPHQTLSQTKKNPSLISCFIFIGAGSTGAAWYVLCLASFSPDVSWARNNNPEPWNKLSPN 60

Query: 60 DQYKFYSVNVDYSKLKKERPDF 81
          DQYK YSVNVDYSKLKKE PDF
Sbjct: 61 DQYKSYSVNVDYSKLKKEGPDF 82


>gi|239750055 PREDICTED: hypothetical protein XP_002347281 [Homo
          sapiens]
          Length = 82

 Score =  120 bits (300), Expect = 3e-28
 Identities = 58/82 (70%), Positives = 64/82 (78%), Gaps = 1/82 (1%)

Query: 1  MLRQIIGQAKKHPSLIPLFVFIGTGATGATLYLLRLALFNPDVCWDRNN-PEPWNKLGPN 59
          M  Q + Q KK+PSLI  F+FIG G+TGA  Y+L LA F+PDV W RNN PEPWNKL PN
Sbjct: 1  MPHQTLSQTKKNPSLISCFIFIGAGSTGAAWYVLCLASFSPDVSWARNNNPEPWNKLSPN 60

Query: 60 DQYKFYSVNVDYSKLKKERPDF 81
          DQYK YSVNVDYSKLKKE PDF
Sbjct: 61 DQYKSYSVNVDYSKLKKEGPDF 82


>gi|239744362 PREDICTED: hypothetical protein XP_002343134 [Homo
          sapiens]
          Length = 82

 Score =  120 bits (300), Expect = 3e-28
 Identities = 58/82 (70%), Positives = 64/82 (78%), Gaps = 1/82 (1%)

Query: 1  MLRQIIGQAKKHPSLIPLFVFIGTGATGATLYLLRLALFNPDVCWDRNN-PEPWNKLGPN 59
          M  Q + Q KK+PSLI  F+FIG G+TGA  Y+L LA F+PDV W RNN PEPWNKL PN
Sbjct: 1  MPHQTLSQTKKNPSLISCFIFIGAGSTGAAWYVLCLASFSPDVSWARNNNPEPWNKLSPN 60

Query: 60 DQYKFYSVNVDYSKLKKERPDF 81
          DQYK YSVNVDYSKLKKE PDF
Sbjct: 61 DQYKSYSVNVDYSKLKKEGPDF 82


>gi|10047138 NADH:ubiquinone oxidoreductase MLRQ subunit homolog
          [Homo sapiens]
          Length = 87

 Score =  110 bits (274), Expect = 3e-25
 Identities = 50/75 (66%), Positives = 58/75 (77%), Gaps = 1/75 (1%)

Query: 8  QAKKHPSLIPLFVFIGTGATGATLYLLRLALFNPDVCWDR-NNPEPWNKLGPNDQYKFYS 66
          Q K+HP +IP+   I  G   A LYLLRLAL +PDVCWDR NNPEPWN+L PNDQYKF +
Sbjct: 13 QIKRHPGIIPMIGLICLGMGSAALYLLRLALRSPDVCWDRKNNPEPWNRLSPNDQYKFLA 72

Query: 67 VNVDYSKLKKERPDF 81
          V+ DY KLKK+RPDF
Sbjct: 73 VSTDYKKLKKDRPDF 87


>gi|14165280 normal mucosa of esophagus specific 1 [Homo sapiens]
          Length = 83

 Score = 42.0 bits (97), Expect = 1e-04
 Identities = 23/67 (34%), Positives = 36/67 (53%), Gaps = 2/67 (2%)

Query: 11 KHPSLIPLFVFIGTGATGATLYLLRLALFNPDVCWDRN-NPEPWNKLGPNDQYKFYSVNV 69
          K   LIPL VF+   A GA+ + +  +L+  DV  DR  NPEPW  + P    K  ++N 
Sbjct: 9  KRKELIPLVVFMTVAAGGASSFAV-YSLWKTDVILDRKKNPEPWETVDPTVPQKLITINQ 67

Query: 70 DYSKLKK 76
           +  +++
Sbjct: 68 QWKPIEE 74


>gi|37694067 normal mucosa of esophagus specific 1 [Homo sapiens]
          Length = 83

 Score = 42.0 bits (97), Expect = 1e-04
 Identities = 23/67 (34%), Positives = 36/67 (53%), Gaps = 2/67 (2%)

Query: 11 KHPSLIPLFVFIGTGATGATLYLLRLALFNPDVCWDRN-NPEPWNKLGPNDQYKFYSVNV 69
          K   LIPL VF+   A GA+ + +  +L+  DV  DR  NPEPW  + P    K  ++N 
Sbjct: 9  KRKELIPLVVFMTVAAGGASSFAV-YSLWKTDVILDRKKNPEPWETVDPTVPQKLITINQ 67

Query: 70 DYSKLKK 76
           +  +++
Sbjct: 68 QWKPIEE 74


>gi|55741655 anoctamin 8 [Homo sapiens]
          Length = 1232

 Score = 27.3 bits (59), Expect = 2.7
 Identities = 17/64 (26%), Positives = 28/64 (43%), Gaps = 2/64 (3%)

Query: 18  LFVFIGTGATGATLYLLRLALFNPDVCWDRNNPEPWNKLGPNDQYKFYSVNVDYSKLKKE 77
           L+ F     T   +  +  ALFN  V W     E W + G    YK+ +++     +++ 
Sbjct: 269 LYTFTEADQTSRDVSCVVFALFN--VIWSTLFLEEWKRRGAELAYKWGTLDSPGEAVEEP 326

Query: 78  RPDF 81
           RP F
Sbjct: 327 RPQF 330


>gi|42542383 solute carrier family 28, member 1 isoform 2 [Homo
           sapiens]
          Length = 175

 Score = 26.9 bits (58), Expect = 3.5
 Identities = 8/15 (53%), Positives = 11/15 (73%)

Query: 45  WDRNNPEPWNKLGPN 59
           W + +P PW+K GPN
Sbjct: 151 WFKRDPRPWSKEGPN 165


>gi|92859871 SMAD family member 6 isoform 1 [Homo sapiens]
          Length = 496

 Score = 25.8 bits (55), Expect = 7.8
 Identities = 8/21 (38%), Positives = 14/21 (66%)

Query: 43  VCWDRNNPEPWNKLGPNDQYK 63
           +C   + P P+++L P D+YK
Sbjct: 269 LCGPESPPPPYSRLSPRDEYK 289


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.322    0.142    0.458 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 3,366,263
Number of Sequences: 37866
Number of extensions: 137001
Number of successful extensions: 242
Number of sequences better than 10.0: 13
Number of HSP's better than 10.0 without gapping: 12
Number of HSP's successfully gapped in prelim test: 1
Number of HSP's that attempted gapping in prelim test: 221
Number of HSP's gapped (non-prelim): 13
length of query: 81
length of database: 18,247,518
effective HSP length: 53
effective length of query: 28
effective length of database: 16,240,620
effective search space: 454737360
effective search space used: 454737360
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 55 (25.8 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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