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Search of human proteins with 4504843
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4504843 potassium inwardly-rectifying channel J6 [Homo
sapiens]
(423 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4504843 potassium inwardly-rectifying channel J6 [Homo sapiens] 850 0.0
gi|24797141 potassium inwardly-rectifying channel J5 [Homo sapiens] 599 e-171
gi|25121970 potassium inwardly-rectifying channel subfamily J9 [... 558 e-159
gi|4504839 potassium inwardly-rectifying channel J3 [Homo sapiens] 452 e-127
gi|23110982 potassium inwardly-rectifying channel, subfamily J, ... 382 e-106
gi|4504835 potassium inwardly-rectifying channel J2 [Homo sapiens] 381 e-106
gi|4826798 potassium inwardly-rectifying channel J4 [Homo sapiens] 380 e-105
gi|23110984 potassium inwardly-rectifying channel J4 [Homo sapiens] 380 e-105
gi|239758082 PREDICTED: similar to thyrotoxic periodic paralysis... 376 e-104
gi|239757993 PREDICTED: similar to inward rectifying K+ channel ... 366 e-101
gi|239757991 PREDICTED: similar to inward rectifying K+ channel ... 366 e-101
gi|239751249 PREDICTED: hypothetical protein XP_002347768 [Homo ... 366 e-101
gi|4826802 potassium inwardly-rectifying channel J8 [Homo sapiens] 349 3e-96
gi|7019439 potassium inwardly-rectifying channel J14 [Homo sapiens] 347 9e-96
gi|25777635 potassium inwardly-rectifying channel J14 [Homo sapi... 347 9e-96
gi|62388888 potassium inwardly-rectifying channel J11 [Homo sapi... 341 8e-94
gi|24497471 potassium inwardly-rectifying channel J1 isoform b [... 316 2e-86
gi|24497467 potassium inwardly-rectifying channel J1 isoform b [... 316 2e-86
gi|4504837 potassium inwardly-rectifying channel J1 isoform a [H... 316 2e-86
gi|148539892 potassium inwardly-rectifying channel J1 isoform b ... 316 2e-86
gi|24497473 potassium inwardly-rectifying channel J1 isoform b [... 316 2e-86
gi|8923823 potassium inwardly-rectifying channel J16 [Homo sapiens] 284 1e-76
gi|25777630 potassium inwardly-rectifying channel J16 [Homo sapi... 284 1e-76
gi|25777628 potassium inwardly-rectifying channel J16 [Homo sapi... 284 1e-76
gi|25121966 potassium inwardly-rectifying channel, subfamily J, ... 269 4e-72
gi|21361127 potassium inwardly-rectifying channel J15 [Homo sapi... 252 4e-67
gi|25777640 potassium inwardly-rectifying channel J15 [Homo sapi... 252 4e-67
gi|25777638 potassium inwardly-rectifying channel J15 [Homo sapi... 252 4e-67
gi|156119627 potassium inwardly-rectifying channel J13 [Homo sap... 183 3e-46
gi|41872577 raft-linking protein [Homo sapiens] 32 1.4
>gi|4504843 potassium inwardly-rectifying channel J6 [Homo sapiens]
Length = 423
Score = 850 bits (2197), Expect = 0.0
Identities = 423/423 (100%), Positives = 423/423 (100%)
Query: 1 MAKLTESMTNVLEGDSMDQDVESPVAIHQPKLPKQARDDLPRHISRDRTKRKIQRYVRKD 60
MAKLTESMTNVLEGDSMDQDVESPVAIHQPKLPKQARDDLPRHISRDRTKRKIQRYVRKD
Sbjct: 1 MAKLTESMTNVLEGDSMDQDVESPVAIHQPKLPKQARDDLPRHISRDRTKRKIQRYVRKD 60
Query: 61 GKCNVHHGNVRETYRYLTDIFTTLVDLKWRFNLLIFVMVYTVTWLFFGMIWWLIAYIRGD 120
GKCNVHHGNVRETYRYLTDIFTTLVDLKWRFNLLIFVMVYTVTWLFFGMIWWLIAYIRGD
Sbjct: 61 GKCNVHHGNVRETYRYLTDIFTTLVDLKWRFNLLIFVMVYTVTWLFFGMIWWLIAYIRGD 120
Query: 121 MDHIEDPSWTPCVTNLNGFVSAFLFSIETETTIGYGYRVITDKCPEGIILLLIQSVLGSI 180
MDHIEDPSWTPCVTNLNGFVSAFLFSIETETTIGYGYRVITDKCPEGIILLLIQSVLGSI
Sbjct: 121 MDHIEDPSWTPCVTNLNGFVSAFLFSIETETTIGYGYRVITDKCPEGIILLLIQSVLGSI 180
Query: 181 VNAFMVGCMFVKISQPKKRAETLVFSTHAVISMRDGKLCLMFRVGDLRNSHIVEASIRAK 240
VNAFMVGCMFVKISQPKKRAETLVFSTHAVISMRDGKLCLMFRVGDLRNSHIVEASIRAK
Sbjct: 181 VNAFMVGCMFVKISQPKKRAETLVFSTHAVISMRDGKLCLMFRVGDLRNSHIVEASIRAK 240
Query: 241 LIKSKQTSEGEFIPLNQTDINVGYYTGDDRLFLVSPLIISHEINQQSPFWEISKAQLPKE 300
LIKSKQTSEGEFIPLNQTDINVGYYTGDDRLFLVSPLIISHEINQQSPFWEISKAQLPKE
Sbjct: 241 LIKSKQTSEGEFIPLNQTDINVGYYTGDDRLFLVSPLIISHEINQQSPFWEISKAQLPKE 300
Query: 301 ELEIVVILEGMVEATGMTCQARSSYITSEILWGYRFTPVLTLEDGFYEVDYNSFHETYET 360
ELEIVVILEGMVEATGMTCQARSSYITSEILWGYRFTPVLTLEDGFYEVDYNSFHETYET
Sbjct: 301 ELEIVVILEGMVEATGMTCQARSSYITSEILWGYRFTPVLTLEDGFYEVDYNSFHETYET 360
Query: 361 STPSLSAKELAELASRAELPLSWSVSSKLNQHAELETEEEEKNLEEQTERNGDVANLENE 420
STPSLSAKELAELASRAELPLSWSVSSKLNQHAELETEEEEKNLEEQTERNGDVANLENE
Sbjct: 361 STPSLSAKELAELASRAELPLSWSVSSKLNQHAELETEEEEKNLEEQTERNGDVANLENE 420
Query: 421 SKV 423
SKV
Sbjct: 421 SKV 423
>gi|24797141 potassium inwardly-rectifying channel J5 [Homo sapiens]
Length = 419
Score = 599 bits (1544), Expect = e-171
Identities = 305/421 (72%), Positives = 345/421 (81%), Gaps = 20/421 (4%)
Query: 12 LEGDS---MDQDVESPVAIHQPK-LPKQARDDLPRHISRDRT------KRKIQRYVRKDG 61
+ GDS M+QD+E V PK +PKQARD +P I+ DRT K+ QRY+ K G
Sbjct: 1 MAGDSRNAMNQDMEIGVTPWDPKKIPKQARDYVP--IATDRTRLLAEGKKPRQRYMEKSG 58
Query: 62 KCNVHHGNVRETYRYLTDIFTTLVDLKWRFNLLIFVMVYTVTWLFFGMIWWLIAYIRGDM 121
KCNVHHGNV+ETYRYL+D+FTTLVDLKWRFNLL+F MVYTVTWLFFG IWWLIAYIRGD+
Sbjct: 59 KCNVHHGNVQETYRYLSDLFTTLVDLKWRFNLLVFTMVYTVTWLFFGFIWWLIAYIRGDL 118
Query: 122 DHIEDPSWTPCVTNLNGFVSAFLFSIETETTIGYGYRVITDKCPEGIILLLIQSVLGSIV 181
DH+ D W PCV NL+GFVSAFLFSIETETTIGYG+RVIT+KCPEGIILLL+Q++LGSIV
Sbjct: 119 DHVGDQEWIPCVENLSGFVSAFLFSIETETTIGYGFRVITEKCPEGIILLLVQAILGSIV 178
Query: 182 NAFMVGCMFVKISQPKKRAETLVFSTHAVISMRDGKLCLMFRVGDLRNSHIVEASIRAKL 241
NAFMVGCMFVKISQPKKRAETL+FS +AVISMRD KLCLMFRVGDLRNSHIVEASIRAKL
Sbjct: 179 NAFMVGCMFVKISQPKKRAETLMFSNNAVISMRDEKLCLMFRVGDLRNSHIVEASIRAKL 238
Query: 242 IKSKQTSEGEFIPLNQTDINVGYYTGDDRLFLVSPLIISHEINQQSPFWEISKAQLPKEE 301
IKS+QT EGEFIPLNQTDINVG+ TGDDRLFLVSPLIISHEINQ+SPFWE+S+AQL +EE
Sbjct: 239 IKSRQTKEGEFIPLNQTDINVGFDTGDDRLFLVSPLIISHEINQKSPFWEMSQAQLHQEE 298
Query: 302 LEIVVILEGMVEATGMTCQARSSYITSEILWGYRFTPVLTLEDGFYEVDYNSFHETYETS 361
E+VVILEGMVEATGMTCQARSSY+ +E+LWG+RFTPVLTLE GFYEVDYN+FH+TYET+
Sbjct: 299 FEVVVILEGMVEATGMTCQARSSYMDTEVLWGHRFTPVLTLEKGFYEVDYNTFHDTYETN 358
Query: 362 TPSLSAKELAELASRAEL--------PLSWSVSSKLNQHAELETEEEEKNLEEQTERNGD 413
TPS AKELAE+ L L + L+ AE E+E K L E G
Sbjct: 359 TPSCCAKELAEMKREGRLLQYLPSPPLLGGCAEAGLDAEAEQNEEDEPKGLGGSREARGS 418
Query: 414 V 414
V
Sbjct: 419 V 419
>gi|25121970 potassium inwardly-rectifying channel subfamily J9
[Homo sapiens]
Length = 393
Score = 558 bits (1439), Expect = e-159
Identities = 270/376 (71%), Positives = 320/376 (85%), Gaps = 2/376 (0%)
Query: 50 KRKIQRYVRKDGKCNVHHGNVRETYRYLTDIFTTLVDLKWRFNLLIFVMVYTVTWLFFGM 109
+R QRYV KDG+CNV GNVRETYRYLTD+FTTLVDL+WR +LL FV+ Y +TWLFFG
Sbjct: 18 RRGRQRYVEKDGRCNVQQGNVRETYRYLTDLFTTLVDLQWRLSLLFFVLAYALTWLFFGA 77
Query: 110 IWWLIAYIRGDMDHIEDPSWTPCVTNLNGFVSAFLFSIETETTIGYGYRVITDKCPEGII 169
IWWLIAY RGD++H+ED +WTPCV NLNGFV+AFLFSIETETTIGYG+RVITD+CPEGI+
Sbjct: 78 IWWLIAYGRGDLEHLEDTAWTPCVNNLNGFVAAFLFSIETETTIGYGHRVITDQCPEGIV 137
Query: 170 LLLIQSVLGSIVNAFMVGCMFVKISQPKKRAETLVFSTHAVISMRDGKLCLMFRVGDLRN 229
LLL+Q++LGS+VNAFMVGCMFVKISQP KRA TLVFS+HAV+S+RDG+LCLMFRVGDLR+
Sbjct: 138 LLLLQAILGSMVNAFMVGCMFVKISQPNKRAATLVFSSHAVVSLRDGRLCLMFRVGDLRS 197
Query: 230 SHIVEASIRAKLIKSKQTSEGEFIPLNQTDINVGYYTGDDRLFLVSPLIISHEINQQSPF 289
SHIVEASIRAKLI+S+QT EGEFIPL+QTD++VG+ TGDDRLFLVSPL+ISHEI+ SPF
Sbjct: 198 SHIVEASIRAKLIRSRQTLEGEFIPLHQTDLSVGFDTGDDRLFLVSPLVISHEIDAASPF 257
Query: 290 WEISKAQLPKEELEIVVILEGMVEATGMTCQARSSYITSEILWGYRFTPVLTLEDGFYEV 349
WE S+ L +++ EIVVILEGMVEATGMTCQARSSY+ E+LWG+RFT VLTLEDGFYEV
Sbjct: 258 WEASRRALERDDFEIVVILEGMVEATGMTCQARSSYLVDEVLWGHRFTSVLTLEDGFYEV 317
Query: 350 DYNSFHETYETSTPSLSAKELAELASRAELPLSWSVSSKLNQHAELETEEEEKNLE--EQ 407
DY SFHET+E TPS SA+ELAE A+R + L WS+ S+L++ E E E E
Sbjct: 318 DYASFHETFEVPTPSCSARELAEAAARLDAHLYWSIPSRLDEKVEEEGAGEGAGGEAGAD 377
Query: 408 TERNGDVANLENESKV 423
E+NG + E+ESKV
Sbjct: 378 KEQNGCLPPPESESKV 393
>gi|4504839 potassium inwardly-rectifying channel J3 [Homo sapiens]
Length = 501
Score = 452 bits (1162), Expect = e-127
Identities = 213/348 (61%), Positives = 277/348 (79%), Gaps = 1/348 (0%)
Query: 50 KRKIQRYVRKDGKCNVHHGNV-RETYRYLTDIFTTLVDLKWRFNLLIFVMVYTVTWLFFG 108
K+K QR+V K+G+CNV HGN+ ET RYL+D+FTTLVDLKWR+NL IF++ YTV WLF
Sbjct: 40 KKKRQRFVDKNGRCNVQHGNLGSETSRYLSDLFTTLVDLKWRWNLFIFILTYTVAWLFMA 99
Query: 109 MIWWLIAYIRGDMDHIEDPSWTPCVTNLNGFVSAFLFSIETETTIGYGYRVITDKCPEGI 168
+WW+IAY RGD++ ++TPCV N+ F SAFLF IETE TIGYGYR ITDKCPEGI
Sbjct: 100 SMWWVIAYTRGDLNKAHVGNYTPCVANVYNFPSAFLFFIETEATIGYGYRYITDKCPEGI 159
Query: 169 ILLLIQSVLGSIVNAFMVGCMFVKISQPKKRAETLVFSTHAVISMRDGKLCLMFRVGDLR 228
IL L QS+LGSIV+AF++GCMF+K+SQPKKRAETL+FS HAVISMRDGKL LMFRVG+LR
Sbjct: 160 ILFLFQSILGSIVDAFLIGCMFIKMSQPKKRAETLMFSEHAVISMRDGKLTLMFRVGNLR 219
Query: 229 NSHIVEASIRAKLIKSKQTSEGEFIPLNQTDINVGYYTGDDRLFLVSPLIISHEINQQSP 288
NSH+V A IR KL+KS+QT EGEF+PL+Q +++VG+ TG D+LFLVSPL I H I+ +SP
Sbjct: 220 NSHMVSAQIRCKLLKSRQTPEGEFLPLDQLELDVGFSTGADQLFLVSPLTICHVIDAKSP 279
Query: 289 FWEISKAQLPKEELEIVVILEGMVEATGMTCQARSSYITSEILWGYRFTPVLTLEDGFYE 348
F+++S+ + E+ EIVVILEG+VE TGMTCQAR+SY E+LWG+RF PV++LE+GF++
Sbjct: 280 FYDLSQRSMQTEQFEIVVILEGIVETTGMTCQARTSYTEDEVLWGHRFFPVISLEEGFFK 339
Query: 349 VDYNSFHETYETSTPSLSAKELAELASRAELPLSWSVSSKLNQHAELE 396
VDY+ FH T+E TP S KE E+ + ++ ++++ +H +E
Sbjct: 340 VDYSQFHATFEVPTPPYSVKEQEEMLLMSSPLIAPAITNSKERHNSVE 387
>gi|23110982 potassium inwardly-rectifying channel, subfamily J,
member 12 [Homo sapiens]
Length = 433
Score = 382 bits (980), Expect = e-106
Identities = 191/368 (51%), Positives = 276/368 (75%), Gaps = 6/368 (1%)
Query: 49 TKRKIQ-RYVRKDGKCNVHHGNVRE-TYRYLTDIFTTLVDLKWRFNLLIFVMVYTVTWLF 106
T+R+ + R+V+K+G+CN+ N+ E + RYL D+FTT VD++WR+ LLIF + + +WL
Sbjct: 38 TRRRCRNRFVKKNGQCNIEFANMDEKSQRYLADMFTTCVDIRWRYMLLIFSLAFLASWLL 97
Query: 107 FGMIWWLIAYIRGDMDHIEDPSWTPCVTNLNGFVSAFLFSIETETTIGYGYRVITDKCPE 166
FG+I+W+IA GD++ E TPCV ++GF++AFLFSIET+TTIGYG R +T++CP
Sbjct: 98 FGIIFWVIAVAHGDLEPAEGRGRTPCVMQVHGFMAAFLFSIETQTTIGYGLRCVTEECPV 157
Query: 167 GIILLLIQSVLGSIVNAFMVGCMFVKISQPKKRAETLVFSTHAVISMRDGKLCLMFRVGD 226
+ +++ QS++G I+++FM+G + K+++PKKRA+TL+FS +AV+++RDGKLCLM+RVG+
Sbjct: 158 AVFMVVAQSIVGCIIDSFMIGAIMAKMARPKKRAQTLLFSHNAVVALRDGKLCLMWRVGN 217
Query: 227 LRNSHIVEASIRAKLIKSKQTSEGEFIPLNQTDINVGYYTGDDRLFLVSPLIISHEINQQ 286
LR SHIVEA +RA+LIK + T EGE+IPL+Q DI+VG+ G DR+FLVSP+ I HEI++
Sbjct: 218 LRKSHIVEAHVRAQLIKPRVTEEGEYIPLDQIDIDVGFDKGLDRIFLVSPITILHEIDEA 277
Query: 287 SPFWEISKAQLPKEELEIVVILEGMVEATGMTCQARSSYITSEILWGYRFTPVLTLEDGF 346
SP + IS+ L ++ EIVVILEGMVEAT MT QARSSY+ +EILWG+RF PVL E
Sbjct: 278 SPLFGISRQDLETDDFEIVVILEGMVEATAMTTQARSSYLANEILWGHRFEPVLFEEKNQ 337
Query: 347 YEVDYNSFHETYET-STPSLSAKELAELASRAELPLSWSVSSKLNQHAELETEEEEKNLE 405
Y++DY+ FH+TYE STP SAK+L E ++ LP + S + N+ A L +EE++
Sbjct: 338 YKIDYSHFHKTYEVPSTPRCSAKDLVE--NKFLLPSANSFCYE-NELAFLSRDEEDEADG 394
Query: 406 EQTERNGD 413
+Q R+ D
Sbjct: 395 DQDGRSRD 402
>gi|4504835 potassium inwardly-rectifying channel J2 [Homo sapiens]
Length = 427
Score = 381 bits (979), Expect = e-106
Identities = 182/320 (56%), Positives = 252/320 (78%), Gaps = 4/320 (1%)
Query: 55 RYVRKDGKCNVHHGNVRET-YRYLTDIFTTLVDLKWRFNLLIFVMVYTVTWLFFGMIWWL 113
R+V+KDG CNV NV E RYL DIFTT VD++WR+ L+IF + + ++WLFFG ++WL
Sbjct: 46 RFVKKDGHCNVQFINVGEKGQRYLADIFTTCVDIRWRWMLVIFCLAFVLSWLFFGCVFWL 105
Query: 114 IAYIRGDMDHIEDPSWTPCVTNLNGFVSAFLFSIETETTIGYGYRVITDKCPEGIILLLI 173
IA + GD+D ++ CV+ +N F +AFLFSIET+TTIGYG+R +TD+CP + +++
Sbjct: 106 IALLHGDLDASKEGK--ACVSEVNSFTAAFLFSIETQTTIGYGFRCVTDECPIAVFMVVF 163
Query: 174 QSVLGSIVNAFMVGCMFVKISQPKKRAETLVFSTHAVISMRDGKLCLMFRVGDLRNSHIV 233
QS++G I++AF++G + K+++PKKR ETLVFS +AVI+MRDGKLCLM+RVG+LR SH+V
Sbjct: 164 QSIVGCIIDAFIIGAVMAKMAKPKKRNETLVFSHNAVIAMRDGKLCLMWRVGNLRKSHLV 223
Query: 234 EASIRAKLIKSKQTSEGEFIPLNQTDINVGYYTGDDRLFLVSPLIISHEINQQSPFWEIS 293
EA +RA+L+KS+ TSEGE+IPL+Q DINVG+ +G DR+FLVSP+ I HEI++ SP +++S
Sbjct: 224 EAHVRAQLLKSRITSEGEYIPLDQIDINVGFDSGIDRIFLVSPITIVHEIDEDSPLYDLS 283
Query: 294 KAQLPKEELEIVVILEGMVEATGMTCQARSSYITSEILWGYRFTPVLTLEDGFYEVDYNS 353
K + + EIVVILEGMVEAT MT Q RSSY+ +EILWG+R+ PVL E +Y+VDY+
Sbjct: 284 KQDIDNADFEIVVILEGMVEATAMTTQCRSSYLANEILWGHRYEPVLFEEKHYYKVDYSR 343
Query: 354 FHETYET-STPSLSAKELAE 372
FH+TYE +TP SA++LAE
Sbjct: 344 FHKTYEVPNTPLCSARDLAE 363
>gi|4826798 potassium inwardly-rectifying channel J4 [Homo sapiens]
Length = 445
Score = 380 bits (975), Expect = e-105
Identities = 193/387 (49%), Positives = 272/387 (70%), Gaps = 21/387 (5%)
Query: 48 RTKRKIQRYVRKDGKCNVHHGNV-RETYRYLTDIFTTLVDLKWRFNLLIFVMVYTVTWLF 106
R KR+ R+V+K+G+CNV+ N+ ++ RY+ DIFTT VD +WR+ L+IF + V+WLF
Sbjct: 14 RRKRR-NRFVKKNGQCNVYFANLSNKSQRYMADIFTTCVDTRWRYMLMIFSAAFLVSWLF 72
Query: 107 FGMIWWLIAYIRGDMDH----------------IEDPSWTPCVTNLNGFVSAFLFSIETE 150
FG+++W IA+ GD++ + PC+ ++NGF+ AFLFS+ET+
Sbjct: 73 FGLLFWCIAFFHGDLEASPGVPAAGGPAAGGGGAAPVAPKPCIMHVNGFLGAFLFSVETQ 132
Query: 151 TTIGYGYRVITDKCPEGIILLLIQSVLGSIVNAFMVGCMFVKISQPKKRAETLVFSTHAV 210
TTIGYG+R +T++CP +I +++QS++G ++++FM+G + K+++PKKRA+TL+FS HAV
Sbjct: 133 TTIGYGFRCVTEECPLAVIAVVVQSIVGCVIDSFMIGTIMAKMARPKKRAQTLLFSHHAV 192
Query: 211 ISMRDGKLCLMFRVGDLRNSHIVEASIRAKLIKSKQTSEGEFIPLNQTDINVGYYTGDDR 270
IS+RDGKLCLM+RVG+LR SHIVEA +RA+LIK T EGE++PL+Q D+NVGY G DR
Sbjct: 193 ISVRDGKLCLMWRVGNLRKSHIVEAHVRAQLIKPYMTQEGEYLPLDQRDLNVGYDIGLDR 252
Query: 271 LFLVSPLIISHEINQQSPFWEISKAQLPKEELEIVVILEGMVEATGMTCQARSSYITSEI 330
+FLVSP+II HEI++ SP + + K +L E+ EIVVILEGMVEAT MT QARSSY+ SEI
Sbjct: 253 IFLVSPIIIVHEIDEDSPLYGMGKEELESEDFEIVVILEGMVEATAMTTQARSSYLASEI 312
Query: 331 LWGYRFTPVLTLEDGFYEVDYNSFHETYETS-TPSLSAKELAELASRAELPLSWSVSSKL 389
LWG+RF PV+ E Y+VDY+ FH+TYE + TP SA+EL E + LP S
Sbjct: 313 LWGHRFEPVVFEEKSHYKVDYSRFHKTYEVAGTPCCSARELQE-SKITVLPAPPPPPSAF 371
Query: 390 NQHAELE-TEEEEKNLEEQTERNGDVA 415
EL +EE+ +EE+ VA
Sbjct: 372 CYENELALMSQEEEEMEEEAAAAAAVA 398
>gi|23110984 potassium inwardly-rectifying channel J4 [Homo sapiens]
Length = 445
Score = 380 bits (975), Expect = e-105
Identities = 193/387 (49%), Positives = 272/387 (70%), Gaps = 21/387 (5%)
Query: 48 RTKRKIQRYVRKDGKCNVHHGNV-RETYRYLTDIFTTLVDLKWRFNLLIFVMVYTVTWLF 106
R KR+ R+V+K+G+CNV+ N+ ++ RY+ DIFTT VD +WR+ L+IF + V+WLF
Sbjct: 14 RRKRR-NRFVKKNGQCNVYFANLSNKSQRYMADIFTTCVDTRWRYMLMIFSAAFLVSWLF 72
Query: 107 FGMIWWLIAYIRGDMDH----------------IEDPSWTPCVTNLNGFVSAFLFSIETE 150
FG+++W IA+ GD++ + PC+ ++NGF+ AFLFS+ET+
Sbjct: 73 FGLLFWCIAFFHGDLEASPGVPAAGGPAAGGGGAAPVAPKPCIMHVNGFLGAFLFSVETQ 132
Query: 151 TTIGYGYRVITDKCPEGIILLLIQSVLGSIVNAFMVGCMFVKISQPKKRAETLVFSTHAV 210
TTIGYG+R +T++CP +I +++QS++G ++++FM+G + K+++PKKRA+TL+FS HAV
Sbjct: 133 TTIGYGFRCVTEECPLAVIAVVVQSIVGCVIDSFMIGTIMAKMARPKKRAQTLLFSHHAV 192
Query: 211 ISMRDGKLCLMFRVGDLRNSHIVEASIRAKLIKSKQTSEGEFIPLNQTDINVGYYTGDDR 270
IS+RDGKLCLM+RVG+LR SHIVEA +RA+LIK T EGE++PL+Q D+NVGY G DR
Sbjct: 193 ISVRDGKLCLMWRVGNLRKSHIVEAHVRAQLIKPYMTQEGEYLPLDQRDLNVGYDIGLDR 252
Query: 271 LFLVSPLIISHEINQQSPFWEISKAQLPKEELEIVVILEGMVEATGMTCQARSSYITSEI 330
+FLVSP+II HEI++ SP + + K +L E+ EIVVILEGMVEAT MT QARSSY+ SEI
Sbjct: 253 IFLVSPIIIVHEIDEDSPLYGMGKEELESEDFEIVVILEGMVEATAMTTQARSSYLASEI 312
Query: 331 LWGYRFTPVLTLEDGFYEVDYNSFHETYETS-TPSLSAKELAELASRAELPLSWSVSSKL 389
LWG+RF PV+ E Y+VDY+ FH+TYE + TP SA+EL E + LP S
Sbjct: 313 LWGHRFEPVVFEEKSHYKVDYSRFHKTYEVAGTPCCSARELQE-SKITVLPAPPPPPSAF 371
Query: 390 NQHAELE-TEEEEKNLEEQTERNGDVA 415
EL +EE+ +EE+ VA
Sbjct: 372 CYENELALMSQEEEEMEEEAAAAAAVA 398
>gi|239758082 PREDICTED: similar to thyrotoxic periodic paralysis
susceptibility ion channel [Homo sapiens]
Length = 433
Score = 376 bits (966), Expect = e-104
Identities = 190/368 (51%), Positives = 274/368 (74%), Gaps = 6/368 (1%)
Query: 49 TKRKIQ-RYVRKDGKCNVHHGNVRE-TYRYLTDIFTTLVDLKWRFNLLIFVMVYTVTWLF 106
T+R+ + R+V+K+G+CN+ N+ E + RYL D+FTT VD++WR+ LLIF + + +WL
Sbjct: 38 TRRRCRNRFVKKNGQCNIAFANMDEKSQRYLADMFTTCVDIRWRYMLLIFSLAFLASWLL 97
Query: 107 FGMIWWLIAYIRGDMDHIEDPSWTPCVTNLNGFVSAFLFSIETETTIGYGYRVITDKCPE 166
FG+I+W+IA GD++ E TPCV ++GF++AFLFSIET+TTIGYG R +T++C
Sbjct: 98 FGVIFWVIAVAHGDLEPAEGHGRTPCVMQVHGFMAAFLFSIETQTTIGYGLRCVTEECLV 157
Query: 167 GIILLLIQSVLGSIVNAFMVGCMFVKISQPKKRAETLVFSTHAVISMRDGKLCLMFRVGD 226
+ +++ QS++G I+++FM+G + K+++PKKRA TL+FS +AV+++RDGKLCLM+RVG+
Sbjct: 158 AVFMVVAQSIVGCIIDSFMIGAIMAKMARPKKRAHTLLFSHNAVVALRDGKLCLMWRVGN 217
Query: 227 LRNSHIVEASIRAKLIKSKQTSEGEFIPLNQTDINVGYYTGDDRLFLVSPLIISHEINQQ 286
LR SHIVEA +RA+LIK + T EGE+IPL+Q DI+VG+ G DR+FLVSP+ I HEI++
Sbjct: 218 LRKSHIVEAHVRAQLIKPRVTEEGEYIPLDQIDIDVGFDKGLDRIFLVSPITILHEIDEA 277
Query: 287 SPFWEISKAQLPKEELEIVVILEGMVEATGMTCQARSSYITSEILWGYRFTPVLTLEDGF 346
SP + IS+ L ++ EIVVILEGMVEAT MT QARSSY+ +EILWG+RF PVL E
Sbjct: 278 SPLFGISRQDLETDDFEIVVILEGMVEATAMTTQARSSYLANEILWGHRFEPVLFEEKNQ 337
Query: 347 YEVDYNSFHETYET-STPSLSAKELAELASRAELPLSWSVSSKLNQHAELETEEEEKNLE 405
Y++DY+ FH+TYE STP SAK+L E ++ LP + S + N+ A L +EE++
Sbjct: 338 YKIDYSHFHKTYEVPSTPRCSAKDLVE--NKFLLPSANSFCYE-NELAFLSRDEEDEADG 394
Query: 406 EQTERNGD 413
+Q R+ D
Sbjct: 395 DQDGRSRD 402
>gi|239757993 PREDICTED: similar to inward rectifying K+ channel
negative regulator Kir2.2v isoform 1 [Homo sapiens]
Length = 432
Score = 366 bits (940), Expect = e-101
Identities = 185/364 (50%), Positives = 265/364 (72%), Gaps = 6/364 (1%)
Query: 50 KRKIQRYVRKDGKCNVHHGNVRE-TYRYLTDIFTTLVDLKWRFNLLIFVMVYTVTWLFFG 108
+R R+V+K+G+CN+ N+ E + RYL DIFTT VD++WR+ LLIF + + +WL FG
Sbjct: 40 RRCHNRFVKKNGQCNIEFANMDEKSQRYLADIFTTCVDIRWRYMLLIFSLAFLASWLLFG 99
Query: 109 MIWWLIAYIRGDMDHIEDPSWTPCVTNLNGFVSAFLFSIETETTIGYGYRVITDKCPEGI 168
+I+W+IA GD++ E TPCV ++GF++AFLFSI+T+ TI YG R +T++CP +
Sbjct: 100 VIFWVIAVAHGDLEPAEGRGRTPCVMQVHGFMAAFLFSIKTQNTISYGLRCVTEECPVAV 159
Query: 169 ILLLIQSVLGSIVNAFMVGCMFVKISQPKKRAETLVFSTHAVISMRDGKLCLMFRVGDLR 228
+++ QS++G I+N+FM+G + K+ +PKKRA+TL+FS +AV+++RDGKLC M+RVG+LR
Sbjct: 160 FMVVAQSIVGCIINSFMIGAIMAKMVRPKKRAQTLLFSHNAVVALRDGKLCFMWRVGNLR 219
Query: 229 NSHIVEASIRAKLIKSKQTSEGEFIPLNQTDINVGYYTGDDRLFLVSPLIISHEINQQSP 288
SHIVEA +RA+LIK + T EGE+IPL+Q DI+VG+ G D FLVSP+ I HEI++ SP
Sbjct: 220 KSHIVEAHVRAQLIKPRVTKEGEYIPLDQIDIDVGFDKGLDHSFLVSPITILHEIDEASP 279
Query: 289 FWEISKAQLPKEELEIVVILEGMVEATGMTCQARSSYITSEILWGYRFTPVLTLEDGFYE 348
+ IS+ L ++ EIV+ILEG+VEAT MT QARSSY+ +EILWG+RF PVL E Y+
Sbjct: 280 LFGISRQDLQMDDFEIVIILEGIVEATAMTTQARSSYLANEILWGHRFEPVL-FEKNQYK 338
Query: 349 VDYNSFHETYET-STPSLSAKELAELASRAELPLSWSVSSKLNQHAELETEEEEKNLEEQ 407
+DY FH+TYE STP SAK+L E ++ LP + S K N+ A L +EE++ +Q
Sbjct: 339 IDYLHFHKTYEVPSTPRCSAKDLVE--NKFLLPRANSFCYK-NELAFLSRDEEDEADGDQ 395
Query: 408 TERN 411
R+
Sbjct: 396 DGRS 399
>gi|239757991 PREDICTED: similar to inward rectifying K+ channel
negative regulator Kir2.2v isoform 2 [Homo sapiens]
Length = 534
Score = 366 bits (940), Expect = e-101
Identities = 185/364 (50%), Positives = 265/364 (72%), Gaps = 6/364 (1%)
Query: 50 KRKIQRYVRKDGKCNVHHGNVRE-TYRYLTDIFTTLVDLKWRFNLLIFVMVYTVTWLFFG 108
+R R+V+K+G+CN+ N+ E + RYL DIFTT VD++WR+ LLIF + + +WL FG
Sbjct: 142 RRCHNRFVKKNGQCNIEFANMDEKSQRYLADIFTTCVDIRWRYMLLIFSLAFLASWLLFG 201
Query: 109 MIWWLIAYIRGDMDHIEDPSWTPCVTNLNGFVSAFLFSIETETTIGYGYRVITDKCPEGI 168
+I+W+IA GD++ E TPCV ++GF++AFLFSI+T+ TI YG R +T++CP +
Sbjct: 202 VIFWVIAVAHGDLEPAEGRGRTPCVMQVHGFMAAFLFSIKTQNTISYGLRCVTEECPVAV 261
Query: 169 ILLLIQSVLGSIVNAFMVGCMFVKISQPKKRAETLVFSTHAVISMRDGKLCLMFRVGDLR 228
+++ QS++G I+N+FM+G + K+ +PKKRA+TL+FS +AV+++RDGKLC M+RVG+LR
Sbjct: 262 FMVVAQSIVGCIINSFMIGAIMAKMVRPKKRAQTLLFSHNAVVALRDGKLCFMWRVGNLR 321
Query: 229 NSHIVEASIRAKLIKSKQTSEGEFIPLNQTDINVGYYTGDDRLFLVSPLIISHEINQQSP 288
SHIVEA +RA+LIK + T EGE+IPL+Q DI+VG+ G D FLVSP+ I HEI++ SP
Sbjct: 322 KSHIVEAHVRAQLIKPRVTKEGEYIPLDQIDIDVGFDKGLDHSFLVSPITILHEIDEASP 381
Query: 289 FWEISKAQLPKEELEIVVILEGMVEATGMTCQARSSYITSEILWGYRFTPVLTLEDGFYE 348
+ IS+ L ++ EIV+ILEG+VEAT MT QARSSY+ +EILWG+RF PVL E Y+
Sbjct: 382 LFGISRQDLQMDDFEIVIILEGIVEATAMTTQARSSYLANEILWGHRFEPVL-FEKNQYK 440
Query: 349 VDYNSFHETYET-STPSLSAKELAELASRAELPLSWSVSSKLNQHAELETEEEEKNLEEQ 407
+DY FH+TYE STP SAK+L E ++ LP + S K N+ A L +EE++ +Q
Sbjct: 441 IDYLHFHKTYEVPSTPRCSAKDLVE--NKFLLPRANSFCYK-NELAFLSRDEEDEADGDQ 497
Query: 408 TERN 411
R+
Sbjct: 498 DGRS 501
>gi|239751249 PREDICTED: hypothetical protein XP_002347768 [Homo
sapiens]
Length = 432
Score = 366 bits (940), Expect = e-101
Identities = 185/364 (50%), Positives = 265/364 (72%), Gaps = 6/364 (1%)
Query: 50 KRKIQRYVRKDGKCNVHHGNVRE-TYRYLTDIFTTLVDLKWRFNLLIFVMVYTVTWLFFG 108
+R R+V+K+G+CN+ N+ E + RYL DIFTT VD++WR+ LLIF + + +WL FG
Sbjct: 40 RRCHNRFVKKNGQCNIEFANMDEKSQRYLADIFTTCVDIRWRYMLLIFSLAFLASWLLFG 99
Query: 109 MIWWLIAYIRGDMDHIEDPSWTPCVTNLNGFVSAFLFSIETETTIGYGYRVITDKCPEGI 168
+I+W+IA GD++ E TPCV ++GF++AFLFSI+T+ TI YG R +T++CP +
Sbjct: 100 VIFWVIAVAHGDLEPAEGRGRTPCVMQVHGFMAAFLFSIKTQNTISYGLRCVTEECPVAV 159
Query: 169 ILLLIQSVLGSIVNAFMVGCMFVKISQPKKRAETLVFSTHAVISMRDGKLCLMFRVGDLR 228
+++ QS++G I+N+FM+G + K+ +PKKRA+TL+FS +AV+++RDGKLC M+RVG+LR
Sbjct: 160 FMVVAQSIVGCIINSFMIGAIMAKMVRPKKRAQTLLFSHNAVVALRDGKLCFMWRVGNLR 219
Query: 229 NSHIVEASIRAKLIKSKQTSEGEFIPLNQTDINVGYYTGDDRLFLVSPLIISHEINQQSP 288
SHIVEA +RA+LIK + T EGE+IPL+Q DI+VG+ G D FLVSP+ I HEI++ SP
Sbjct: 220 KSHIVEAHVRAQLIKPRVTKEGEYIPLDQIDIDVGFDKGLDHSFLVSPITILHEIDEASP 279
Query: 289 FWEISKAQLPKEELEIVVILEGMVEATGMTCQARSSYITSEILWGYRFTPVLTLEDGFYE 348
+ IS+ L ++ EIV+ILEG+VEAT MT QARSSY+ +EILWG+RF PVL E Y+
Sbjct: 280 LFGISRQDLQMDDFEIVIILEGIVEATAMTTQARSSYLANEILWGHRFEPVL-FEKNQYK 338
Query: 349 VDYNSFHETYET-STPSLSAKELAELASRAELPLSWSVSSKLNQHAELETEEEEKNLEEQ 407
+DY FH+TYE STP SAK+L E ++ LP + S K N+ A L +EE++ +Q
Sbjct: 339 IDYLHFHKTYEVPSTPRCSAKDLVE--NKFLLPRANSFCYK-NELAFLSRDEEDEADGDQ 395
Query: 408 TERN 411
R+
Sbjct: 396 DGRS 399
>gi|4826802 potassium inwardly-rectifying channel J8 [Homo sapiens]
Length = 424
Score = 349 bits (895), Expect = 3e-96
Identities = 171/352 (48%), Positives = 244/352 (69%), Gaps = 10/352 (2%)
Query: 32 LPKQARDDLPRHISRDRTKRKIQRYVRKDGKCNVHHGNVRETYRYLTDIFTTLVDLKWRF 91
L + A ++L + RDR + R++ K G CN+ H N+RE R+L DIFTTLVDLKWR
Sbjct: 14 LARIAAENLRKPRIRDRLPKA--RFIAKSGACNLAHKNIREQGRFLQDIFTTLVDLKWRH 71
Query: 92 NLLIFVMVYTVTWLFFGMIWWLIAYIRGDMDHIEDPSW--------TPCVTNLNGFVSAF 143
L+IF M + +WL F ++WWL+A+ GD+ + S T CVTN+ F SAF
Sbjct: 72 TLVIFTMSFLCSWLLFAIMWWLVAFAHGDIYAYMEKSGMEKSGLESTVCVTNVRSFTSAF 131
Query: 144 LFSIETETTIGYGYRVITDKCPEGIILLLIQSVLGSIVNAFMVGCMFVKISQPKKRAETL 203
LFSIE + TIG+G R++T++CP I +L++Q+++G I+NA M+GC+F+K +Q +RAETL
Sbjct: 132 LFSIEVQVTIGFGGRMMTEECPLAITVLILQNIVGLIINAVMLGCIFMKTAQAHRRAETL 191
Query: 204 VFSTHAVISMRDGKLCLMFRVGDLRNSHIVEASIRAKLIKSKQTSEGEFIPLNQTDINVG 263
+FS HAVI++R+GKLC MFRVGDLR S I+ AS+R +++K T EGE +P++Q DI V
Sbjct: 192 IFSRHAVIAVRNGKLCFMFRVGDLRKSMIISASVRIQVVKKTTTPEGEVVPIHQLDIPVD 251
Query: 264 YYTGDDRLFLVSPLIISHEINQQSPFWEISKAQLPKEELEIVVILEGMVEATGMTCQARS 323
+ +FLV+PLII H I+++SP ++IS L ++LE++VILEG+VE TG+T QAR+
Sbjct: 252 NPIESNNIFLVAPLIICHVIDKRSPLYDISATDLANQDLEVIVILEGVVETTGITTQART 311
Query: 324 SYITSEILWGYRFTPVLTLEDGFYEVDYNSFHETYETSTPSLSAKELAELAS 375
SYI EI WG+RF ++T E+G Y VDY+ F T + + P SA+EL E S
Sbjct: 312 SYIAEEIQWGHRFVSIVTEEEGVYSVDYSKFGNTVKVAAPRCSARELDEKPS 363
>gi|7019439 potassium inwardly-rectifying channel J14 [Homo sapiens]
Length = 436
Score = 347 bits (891), Expect = 9e-96
Identities = 175/369 (47%), Positives = 252/369 (68%), Gaps = 9/369 (2%)
Query: 51 RKIQRYVRKDGKCNVHHGNVR-ETYRYLTDIFTTLVDLKWRFNLLIFVMVYTVTWLFFGM 109
R+ R+V+KDG CNV N+ + RYL+D+FTT VD++WR+ L+F + +WL FG+
Sbjct: 47 RRRGRFVKKDGHCNVRFVNLGGQGARYLSDLFTTCVDVRWRWMCLLFSCSFLASWLLFGL 106
Query: 110 IWWLIAYIRGDMDHIEDPSWTPCVTNLNGFVSAFLFSIETETTIGYGYRVITDKCPEGII 169
+WLIA + GD+ P+ PC +++ F++AFLF++ET+T+IGYG R +T++CP +
Sbjct: 107 AFWLIASLHGDLAAPPPPA--PCFSHVASFLAAFLFALETQTSIGYGVRSVTEECPAAVA 164
Query: 170 LLLIQSVLGSIVNAFMVGCMFVKISQPKKRAETLVFSTHAVISMRDGKLCLMFRVGDLRN 229
+++Q + G +++AF+VG + K+++PKKR ETLVFS +AV+++RD +LCLM+RVG+LR
Sbjct: 165 AVVLQCIAGCVLDAFVVGAVMAKMAKPKKRNETLVFSENAVVALRDHRLCLMWRVGNLRR 224
Query: 230 SHIVEASIRAKLIKSKQTSEGEFIPLNQTDINVGYYTGDDRLFLVSPLIISHEINQQSPF 289
SH+VEA +RA+L++ + T EGE+IPL+ D++VG+ G DR+FLVSP+ I HEI+ SP
Sbjct: 225 SHLVEAHVRAQLLQPRVTPEGEYIPLDHQDVDVGFDGGTDRIFLVSPITIVHEIDSASPL 284
Query: 290 WEISKAQLPKEELEIVVILEGMVEATGMTCQARSSYITSEILWGYRFTPVLTLEDGFYEV 349
+E+ +A+L + + E+VVILEGMVEAT MT Q RSSY+ E+LWG+RF PVL YEV
Sbjct: 285 YELGRAELARADFELVVILEGMVEATAMTTQCRSSYLPGELLWGHRFEPVLFQRGSQYEV 344
Query: 350 DYNSFHETYET-STPSLSAKELAELASRAELPLSWSVSSKL-----NQHAELETEEEEKN 403
DY FH TYE TP SAKEL E A +A L S L L +EE
Sbjct: 345 DYRHFHRTYEVPGTPVCSAKELDERAEQASHSLKSSFPGSLTAFCYENELALSCCQEEDE 404
Query: 404 LEEQTERNG 412
+E E NG
Sbjct: 405 DDETEEGNG 413
>gi|25777635 potassium inwardly-rectifying channel J14 [Homo
sapiens]
Length = 436
Score = 347 bits (891), Expect = 9e-96
Identities = 175/369 (47%), Positives = 252/369 (68%), Gaps = 9/369 (2%)
Query: 51 RKIQRYVRKDGKCNVHHGNVR-ETYRYLTDIFTTLVDLKWRFNLLIFVMVYTVTWLFFGM 109
R+ R+V+KDG CNV N+ + RYL+D+FTT VD++WR+ L+F + +WL FG+
Sbjct: 47 RRRGRFVKKDGHCNVRFVNLGGQGARYLSDLFTTCVDVRWRWMCLLFSCSFLASWLLFGL 106
Query: 110 IWWLIAYIRGDMDHIEDPSWTPCVTNLNGFVSAFLFSIETETTIGYGYRVITDKCPEGII 169
+WLIA + GD+ P+ PC +++ F++AFLF++ET+T+IGYG R +T++CP +
Sbjct: 107 AFWLIASLHGDLAAPPPPA--PCFSHVASFLAAFLFALETQTSIGYGVRSVTEECPAAVA 164
Query: 170 LLLIQSVLGSIVNAFMVGCMFVKISQPKKRAETLVFSTHAVISMRDGKLCLMFRVGDLRN 229
+++Q + G +++AF+VG + K+++PKKR ETLVFS +AV+++RD +LCLM+RVG+LR
Sbjct: 165 AVVLQCIAGCVLDAFVVGAVMAKMAKPKKRNETLVFSENAVVALRDHRLCLMWRVGNLRR 224
Query: 230 SHIVEASIRAKLIKSKQTSEGEFIPLNQTDINVGYYTGDDRLFLVSPLIISHEINQQSPF 289
SH+VEA +RA+L++ + T EGE+IPL+ D++VG+ G DR+FLVSP+ I HEI+ SP
Sbjct: 225 SHLVEAHVRAQLLQPRVTPEGEYIPLDHQDVDVGFDGGTDRIFLVSPITIVHEIDSASPL 284
Query: 290 WEISKAQLPKEELEIVVILEGMVEATGMTCQARSSYITSEILWGYRFTPVLTLEDGFYEV 349
+E+ +A+L + + E+VVILEGMVEAT MT Q RSSY+ E+LWG+RF PVL YEV
Sbjct: 285 YELGRAELARADFELVVILEGMVEATAMTTQCRSSYLPGELLWGHRFEPVLFQRGSQYEV 344
Query: 350 DYNSFHETYET-STPSLSAKELAELASRAELPLSWSVSSKL-----NQHAELETEEEEKN 403
DY FH TYE TP SAKEL E A +A L S L L +EE
Sbjct: 345 DYRHFHRTYEVPGTPVCSAKELDERAEQASHSLKSSFPGSLTAFCYENELALSCCQEEDE 404
Query: 404 LEEQTERNG 412
+E E NG
Sbjct: 405 DDETEEGNG 413
>gi|62388888 potassium inwardly-rectifying channel J11 [Homo
sapiens]
Length = 390
Score = 341 bits (874), Expect = 8e-94
Identities = 162/328 (49%), Positives = 234/328 (71%), Gaps = 2/328 (0%)
Query: 46 RDRTKRKIQRYVRKDGKCNVHHGNVRETYRYLTDIFTTLVDLKWRFNLLIFVMVYTVTWL 105
R R +++ R+V K G CNV H N+RE R+L D+FTTLVDLKW LLIF M + +WL
Sbjct: 25 RYRARQRRARFVSKKGNCNVAHKNIREQGRFLQDVFTTLVDLKWPHTLLIFTMSFLCSWL 84
Query: 106 FFGMIWWLIAYIRGDMDHIEDPSWTPCVTNLNGFVSAFLFSIETETTIGYGYRVITDKCP 165
F M WWLIA+ GD+ E + PCVT+++ F SAFLFSIE + TIG+G R++T++CP
Sbjct: 85 LFAMAWWLIAFAHGDLAPSEGTA-EPCVTSIHSFSSAFLFSIEVQVTIGFGGRMVTEECP 143
Query: 166 EGIILLLIQSVLGSIVNAFMVGCMFVKISQPKKRAETLVFSTHAVISMRDGKLCLMFRVG 225
I++L++Q+++G ++NA M+GC+F+K +Q +RAETL+FS HAVI++R G+LC M RVG
Sbjct: 144 LAILILIVQNIVGLMINAIMLGCIFMKTAQAHRRAETLIFSKHAVIALRHGRLCFMLRVG 203
Query: 226 DLRNSHIVEASIRAKLIKSKQTSEGEFIPLNQTDINVGYYTGDDRLFLVSPLIISHEINQ 285
DLR S I+ A+I ++++ + EGE +PL+Q DI + G + +FLV+PLII H I+
Sbjct: 204 DLRKSMIISATIHMQVVRKTTSPEGEVVPLHQVDIPMENGVGGNSIFLVAPLIIYHVIDA 263
Query: 286 QSPFWEISKAQL-PKEELEIVVILEGMVEATGMTCQARSSYITSEILWGYRFTPVLTLED 344
SP ++++ + L ++LEI+VILEG+VE TG+T QAR+SY+ EILWG RF P++ ED
Sbjct: 264 NSPLYDLAPSDLHHHQDLEIIVILEGVVETTGITTQARTSYLADEILWGQRFVPIVAEED 323
Query: 345 GFYEVDYNSFHETYETSTPSLSAKELAE 372
G Y VDY+ F T + TP +A++L E
Sbjct: 324 GRYSVDYSKFGNTVKVPTPLCTARQLDE 351
>gi|24497471 potassium inwardly-rectifying channel J1 isoform b
[Homo sapiens]
Length = 372
Score = 316 bits (810), Expect = 2e-86
Identities = 150/317 (47%), Positives = 219/317 (69%), Gaps = 4/317 (1%)
Query: 51 RKIQRYVRKDGKCNVHHGNVRETYRYL--TDIFTTLVDLKWRFNLLIFVMVYTVTWLFFG 108
R+ R V KDG+CN+ GNV R++ DI+TT++DLKWR+ + IF+ + +W FFG
Sbjct: 18 RQRARLVSKDGRCNIEFGNVEAQSRFIFFVDIWTTVLDLKWRYKMTIFITAFLGSWFFFG 77
Query: 109 MIWWLIAYIRGDMDHIE-DPSWTPCVTNLNGFVSAFLFSIETETTIGYGYRVITDKCPEG 167
++W+ +AYI D+ + TPCV N+NG SAFLFS+ET+ TIGYG+R +T++C
Sbjct: 78 LLWYAVAYIHKDLPEFHPSANHTPCVENINGLTSAFLFSLETQVTIGYGFRCVTEQCATA 137
Query: 168 IILLLIQSVLGSIVNAFMVGCMFVKISQPKKRAETLVFSTHAVISMRDGKLCLMFRVGDL 227
I LL+ QS+LG I+N+FM G + KIS+PKKRA+T+ FS +AVIS R GKLCL+ RV +L
Sbjct: 138 IFLLIFQSILGVIINSFMCGAILAKISRPKKRAKTITFSKNAVISKRGGKLCLLIRVANL 197
Query: 228 RNSHIVEASIRAKLIKSKQTSEGEFIPLNQTDINVGYYTGDDRLFLVSPLIISHEINQQS 287
R S ++ + I KL+K+ T EGE I L+Q +IN G++ LF +SPL I H I+ S
Sbjct: 198 RKSLLIGSHIYGKLLKTTVTPEGETIILDQININFVVDAGNENLFFISPLTIYHVIDHNS 257
Query: 288 PFWEISKAQLPKEELEIVVILEGMVEATGMTCQARSSYITSEILWGYRFTPVLT-LEDGF 346
PF+ ++ L +++ E+VV L+G VE+T TCQ R+SY+ E+LWGYRF P+++ ++G
Sbjct: 258 PFFHMAAETLLQQDFELVVFLDGTVESTSATCQVRTSYVPEEVLWGYRFAPIVSKTKEGK 317
Query: 347 YEVDYNSFHETYETSTP 363
Y VD+++F +T E TP
Sbjct: 318 YRVDFHNFSKTVEVETP 334
>gi|24497467 potassium inwardly-rectifying channel J1 isoform b
[Homo sapiens]
Length = 372
Score = 316 bits (810), Expect = 2e-86
Identities = 150/317 (47%), Positives = 219/317 (69%), Gaps = 4/317 (1%)
Query: 51 RKIQRYVRKDGKCNVHHGNVRETYRYL--TDIFTTLVDLKWRFNLLIFVMVYTVTWLFFG 108
R+ R V KDG+CN+ GNV R++ DI+TT++DLKWR+ + IF+ + +W FFG
Sbjct: 18 RQRARLVSKDGRCNIEFGNVEAQSRFIFFVDIWTTVLDLKWRYKMTIFITAFLGSWFFFG 77
Query: 109 MIWWLIAYIRGDMDHIE-DPSWTPCVTNLNGFVSAFLFSIETETTIGYGYRVITDKCPEG 167
++W+ +AYI D+ + TPCV N+NG SAFLFS+ET+ TIGYG+R +T++C
Sbjct: 78 LLWYAVAYIHKDLPEFHPSANHTPCVENINGLTSAFLFSLETQVTIGYGFRCVTEQCATA 137
Query: 168 IILLLIQSVLGSIVNAFMVGCMFVKISQPKKRAETLVFSTHAVISMRDGKLCLMFRVGDL 227
I LL+ QS+LG I+N+FM G + KIS+PKKRA+T+ FS +AVIS R GKLCL+ RV +L
Sbjct: 138 IFLLIFQSILGVIINSFMCGAILAKISRPKKRAKTITFSKNAVISKRGGKLCLLIRVANL 197
Query: 228 RNSHIVEASIRAKLIKSKQTSEGEFIPLNQTDINVGYYTGDDRLFLVSPLIISHEINQQS 287
R S ++ + I KL+K+ T EGE I L+Q +IN G++ LF +SPL I H I+ S
Sbjct: 198 RKSLLIGSHIYGKLLKTTVTPEGETIILDQININFVVDAGNENLFFISPLTIYHVIDHNS 257
Query: 288 PFWEISKAQLPKEELEIVVILEGMVEATGMTCQARSSYITSEILWGYRFTPVLT-LEDGF 346
PF+ ++ L +++ E+VV L+G VE+T TCQ R+SY+ E+LWGYRF P+++ ++G
Sbjct: 258 PFFHMAAETLLQQDFELVVFLDGTVESTSATCQVRTSYVPEEVLWGYRFAPIVSKTKEGK 317
Query: 347 YEVDYNSFHETYETSTP 363
Y VD+++F +T E TP
Sbjct: 318 YRVDFHNFSKTVEVETP 334
>gi|4504837 potassium inwardly-rectifying channel J1 isoform a [Homo
sapiens]
Length = 391
Score = 316 bits (810), Expect = 2e-86
Identities = 150/317 (47%), Positives = 219/317 (69%), Gaps = 4/317 (1%)
Query: 51 RKIQRYVRKDGKCNVHHGNVRETYRYL--TDIFTTLVDLKWRFNLLIFVMVYTVTWLFFG 108
R+ R V KDG+CN+ GNV R++ DI+TT++DLKWR+ + IF+ + +W FFG
Sbjct: 37 RQRARLVSKDGRCNIEFGNVEAQSRFIFFVDIWTTVLDLKWRYKMTIFITAFLGSWFFFG 96
Query: 109 MIWWLIAYIRGDMDHIE-DPSWTPCVTNLNGFVSAFLFSIETETTIGYGYRVITDKCPEG 167
++W+ +AYI D+ + TPCV N+NG SAFLFS+ET+ TIGYG+R +T++C
Sbjct: 97 LLWYAVAYIHKDLPEFHPSANHTPCVENINGLTSAFLFSLETQVTIGYGFRCVTEQCATA 156
Query: 168 IILLLIQSVLGSIVNAFMVGCMFVKISQPKKRAETLVFSTHAVISMRDGKLCLMFRVGDL 227
I LL+ QS+LG I+N+FM G + KIS+PKKRA+T+ FS +AVIS R GKLCL+ RV +L
Sbjct: 157 IFLLIFQSILGVIINSFMCGAILAKISRPKKRAKTITFSKNAVISKRGGKLCLLIRVANL 216
Query: 228 RNSHIVEASIRAKLIKSKQTSEGEFIPLNQTDINVGYYTGDDRLFLVSPLIISHEINQQS 287
R S ++ + I KL+K+ T EGE I L+Q +IN G++ LF +SPL I H I+ S
Sbjct: 217 RKSLLIGSHIYGKLLKTTVTPEGETIILDQININFVVDAGNENLFFISPLTIYHVIDHNS 276
Query: 288 PFWEISKAQLPKEELEIVVILEGMVEATGMTCQARSSYITSEILWGYRFTPVLT-LEDGF 346
PF+ ++ L +++ E+VV L+G VE+T TCQ R+SY+ E+LWGYRF P+++ ++G
Sbjct: 277 PFFHMAAETLLQQDFELVVFLDGTVESTSATCQVRTSYVPEEVLWGYRFAPIVSKTKEGK 336
Query: 347 YEVDYNSFHETYETSTP 363
Y VD+++F +T E TP
Sbjct: 337 YRVDFHNFSKTVEVETP 353
>gi|148539892 potassium inwardly-rectifying channel J1 isoform b
[Homo sapiens]
Length = 372
Score = 316 bits (810), Expect = 2e-86
Identities = 150/317 (47%), Positives = 219/317 (69%), Gaps = 4/317 (1%)
Query: 51 RKIQRYVRKDGKCNVHHGNVRETYRYL--TDIFTTLVDLKWRFNLLIFVMVYTVTWLFFG 108
R+ R V KDG+CN+ GNV R++ DI+TT++DLKWR+ + IF+ + +W FFG
Sbjct: 18 RQRARLVSKDGRCNIEFGNVEAQSRFIFFVDIWTTVLDLKWRYKMTIFITAFLGSWFFFG 77
Query: 109 MIWWLIAYIRGDMDHIE-DPSWTPCVTNLNGFVSAFLFSIETETTIGYGYRVITDKCPEG 167
++W+ +AYI D+ + TPCV N+NG SAFLFS+ET+ TIGYG+R +T++C
Sbjct: 78 LLWYAVAYIHKDLPEFHPSANHTPCVENINGLTSAFLFSLETQVTIGYGFRCVTEQCATA 137
Query: 168 IILLLIQSVLGSIVNAFMVGCMFVKISQPKKRAETLVFSTHAVISMRDGKLCLMFRVGDL 227
I LL+ QS+LG I+N+FM G + KIS+PKKRA+T+ FS +AVIS R GKLCL+ RV +L
Sbjct: 138 IFLLIFQSILGVIINSFMCGAILAKISRPKKRAKTITFSKNAVISKRGGKLCLLIRVANL 197
Query: 228 RNSHIVEASIRAKLIKSKQTSEGEFIPLNQTDINVGYYTGDDRLFLVSPLIISHEINQQS 287
R S ++ + I KL+K+ T EGE I L+Q +IN G++ LF +SPL I H I+ S
Sbjct: 198 RKSLLIGSHIYGKLLKTTVTPEGETIILDQININFVVDAGNENLFFISPLTIYHVIDHNS 257
Query: 288 PFWEISKAQLPKEELEIVVILEGMVEATGMTCQARSSYITSEILWGYRFTPVLT-LEDGF 346
PF+ ++ L +++ E+VV L+G VE+T TCQ R+SY+ E+LWGYRF P+++ ++G
Sbjct: 258 PFFHMAAETLLQQDFELVVFLDGTVESTSATCQVRTSYVPEEVLWGYRFAPIVSKTKEGK 317
Query: 347 YEVDYNSFHETYETSTP 363
Y VD+++F +T E TP
Sbjct: 318 YRVDFHNFSKTVEVETP 334
>gi|24497473 potassium inwardly-rectifying channel J1 isoform b
[Homo sapiens]
Length = 372
Score = 316 bits (810), Expect = 2e-86
Identities = 150/317 (47%), Positives = 219/317 (69%), Gaps = 4/317 (1%)
Query: 51 RKIQRYVRKDGKCNVHHGNVRETYRYL--TDIFTTLVDLKWRFNLLIFVMVYTVTWLFFG 108
R+ R V KDG+CN+ GNV R++ DI+TT++DLKWR+ + IF+ + +W FFG
Sbjct: 18 RQRARLVSKDGRCNIEFGNVEAQSRFIFFVDIWTTVLDLKWRYKMTIFITAFLGSWFFFG 77
Query: 109 MIWWLIAYIRGDMDHIE-DPSWTPCVTNLNGFVSAFLFSIETETTIGYGYRVITDKCPEG 167
++W+ +AYI D+ + TPCV N+NG SAFLFS+ET+ TIGYG+R +T++C
Sbjct: 78 LLWYAVAYIHKDLPEFHPSANHTPCVENINGLTSAFLFSLETQVTIGYGFRCVTEQCATA 137
Query: 168 IILLLIQSVLGSIVNAFMVGCMFVKISQPKKRAETLVFSTHAVISMRDGKLCLMFRVGDL 227
I LL+ QS+LG I+N+FM G + KIS+PKKRA+T+ FS +AVIS R GKLCL+ RV +L
Sbjct: 138 IFLLIFQSILGVIINSFMCGAILAKISRPKKRAKTITFSKNAVISKRGGKLCLLIRVANL 197
Query: 228 RNSHIVEASIRAKLIKSKQTSEGEFIPLNQTDINVGYYTGDDRLFLVSPLIISHEINQQS 287
R S ++ + I KL+K+ T EGE I L+Q +IN G++ LF +SPL I H I+ S
Sbjct: 198 RKSLLIGSHIYGKLLKTTVTPEGETIILDQININFVVDAGNENLFFISPLTIYHVIDHNS 257
Query: 288 PFWEISKAQLPKEELEIVVILEGMVEATGMTCQARSSYITSEILWGYRFTPVLT-LEDGF 346
PF+ ++ L +++ E+VV L+G VE+T TCQ R+SY+ E+LWGYRF P+++ ++G
Sbjct: 258 PFFHMAAETLLQQDFELVVFLDGTVESTSATCQVRTSYVPEEVLWGYRFAPIVSKTKEGK 317
Query: 347 YEVDYNSFHETYETSTP 363
Y VD+++F +T E TP
Sbjct: 318 YRVDFHNFSKTVEVETP 334
>gi|8923823 potassium inwardly-rectifying channel J16 [Homo sapiens]
Length = 418
Score = 284 bits (726), Expect = 1e-76
Identities = 140/331 (42%), Positives = 221/331 (66%), Gaps = 9/331 (2%)
Query: 41 PRHISRDRTKRKIQRYVRKDGKCNVHHGNV-RETYRYLTDIFTTLVDLKWRFNLLIFVMV 99
P HI ++ +R +R + KDG CNV+ ++ E Y+ DIFTTLVD KWR +IF +
Sbjct: 22 PEHIIAEK-RRARRRLLHKDGSCNVYFKHIFGEWGSYVVDIFTTLVDTKWRHMFVIFSLS 80
Query: 100 YTVTWLFFGMIWWLIAYIRGDMDHIEDPSWTPCVTNLNGFVSAFLFSIETETTIGYGYRV 159
Y ++WL FG ++WLIA+ GD+ + DP TPCV N++ F AFLFS+ET+TTIGYGYR
Sbjct: 81 YILSWLIFGSVFWLIAFHHGDL--LNDPDITPCVDNVHSFTGAFLFSLETQTTIGYGYRC 138
Query: 160 ITDKCPEGIILLLIQSVLGSIVNAFMVGCMFVKISQPKKRAETLVFSTHAVISMRDGKLC 219
+T++C ++++++QS+L I+N F++G K++ +KRA+T+ FS A+I MRDGKLC
Sbjct: 139 VTEECSVAVLMVILQSILSCIINTFIIGAALAKMATARKRAQTIRFSYFALIGMRDGKLC 198
Query: 220 LMFRVGDLRNSHIVEASIRAKLIKSKQTSEGEFIPLNQTDINVGYYTGDDRLFLVSPLII 279
LM+R+GD R +H+VE ++RA+L++ + SEG + + D+ + +D++ LV+P+ I
Sbjct: 199 LMWRIGDFRPNHVVEGTVRAQLLRYTEDSEGR-MTMAFKDLKL----VNDQIILVTPVTI 253
Query: 280 SHEINQQSPFWEISKAQLPKEELEIVVILEGMVEATGMTCQARSSYITSEILWGYRFTPV 339
HEI+ +SP + + + + K+ EI+V ++TG + Q+RSSY+ EILWG+RF V
Sbjct: 254 VHEIDHESPLYALDRKAVAKDNFEILVTFIYTGDSTGTSHQSRSSYVPREILWGHRFNDV 313
Query: 340 LTLEDGFYEVDYNSFHETYETSTPSLSAKEL 370
L ++ +Y+V+ F + E P SAK+L
Sbjct: 314 LEVKRKYYKVNCLQFEGSVEVYAPFCSAKQL 344
>gi|25777630 potassium inwardly-rectifying channel J16 [Homo
sapiens]
Length = 418
Score = 284 bits (726), Expect = 1e-76
Identities = 140/331 (42%), Positives = 221/331 (66%), Gaps = 9/331 (2%)
Query: 41 PRHISRDRTKRKIQRYVRKDGKCNVHHGNV-RETYRYLTDIFTTLVDLKWRFNLLIFVMV 99
P HI ++ +R +R + KDG CNV+ ++ E Y+ DIFTTLVD KWR +IF +
Sbjct: 22 PEHIIAEK-RRARRRLLHKDGSCNVYFKHIFGEWGSYVVDIFTTLVDTKWRHMFVIFSLS 80
Query: 100 YTVTWLFFGMIWWLIAYIRGDMDHIEDPSWTPCVTNLNGFVSAFLFSIETETTIGYGYRV 159
Y ++WL FG ++WLIA+ GD+ + DP TPCV N++ F AFLFS+ET+TTIGYGYR
Sbjct: 81 YILSWLIFGSVFWLIAFHHGDL--LNDPDITPCVDNVHSFTGAFLFSLETQTTIGYGYRC 138
Query: 160 ITDKCPEGIILLLIQSVLGSIVNAFMVGCMFVKISQPKKRAETLVFSTHAVISMRDGKLC 219
+T++C ++++++QS+L I+N F++G K++ +KRA+T+ FS A+I MRDGKLC
Sbjct: 139 VTEECSVAVLMVILQSILSCIINTFIIGAALAKMATARKRAQTIRFSYFALIGMRDGKLC 198
Query: 220 LMFRVGDLRNSHIVEASIRAKLIKSKQTSEGEFIPLNQTDINVGYYTGDDRLFLVSPLII 279
LM+R+GD R +H+VE ++RA+L++ + SEG + + D+ + +D++ LV+P+ I
Sbjct: 199 LMWRIGDFRPNHVVEGTVRAQLLRYTEDSEGR-MTMAFKDLKL----VNDQIILVTPVTI 253
Query: 280 SHEINQQSPFWEISKAQLPKEELEIVVILEGMVEATGMTCQARSSYITSEILWGYRFTPV 339
HEI+ +SP + + + + K+ EI+V ++TG + Q+RSSY+ EILWG+RF V
Sbjct: 254 VHEIDHESPLYALDRKAVAKDNFEILVTFIYTGDSTGTSHQSRSSYVPREILWGHRFNDV 313
Query: 340 LTLEDGFYEVDYNSFHETYETSTPSLSAKEL 370
L ++ +Y+V+ F + E P SAK+L
Sbjct: 314 LEVKRKYYKVNCLQFEGSVEVYAPFCSAKQL 344
>gi|25777628 potassium inwardly-rectifying channel J16 [Homo
sapiens]
Length = 418
Score = 284 bits (726), Expect = 1e-76
Identities = 140/331 (42%), Positives = 221/331 (66%), Gaps = 9/331 (2%)
Query: 41 PRHISRDRTKRKIQRYVRKDGKCNVHHGNV-RETYRYLTDIFTTLVDLKWRFNLLIFVMV 99
P HI ++ +R +R + KDG CNV+ ++ E Y+ DIFTTLVD KWR +IF +
Sbjct: 22 PEHIIAEK-RRARRRLLHKDGSCNVYFKHIFGEWGSYVVDIFTTLVDTKWRHMFVIFSLS 80
Query: 100 YTVTWLFFGMIWWLIAYIRGDMDHIEDPSWTPCVTNLNGFVSAFLFSIETETTIGYGYRV 159
Y ++WL FG ++WLIA+ GD+ + DP TPCV N++ F AFLFS+ET+TTIGYGYR
Sbjct: 81 YILSWLIFGSVFWLIAFHHGDL--LNDPDITPCVDNVHSFTGAFLFSLETQTTIGYGYRC 138
Query: 160 ITDKCPEGIILLLIQSVLGSIVNAFMVGCMFVKISQPKKRAETLVFSTHAVISMRDGKLC 219
+T++C ++++++QS+L I+N F++G K++ +KRA+T+ FS A+I MRDGKLC
Sbjct: 139 VTEECSVAVLMVILQSILSCIINTFIIGAALAKMATARKRAQTIRFSYFALIGMRDGKLC 198
Query: 220 LMFRVGDLRNSHIVEASIRAKLIKSKQTSEGEFIPLNQTDINVGYYTGDDRLFLVSPLII 279
LM+R+GD R +H+VE ++RA+L++ + SEG + + D+ + +D++ LV+P+ I
Sbjct: 199 LMWRIGDFRPNHVVEGTVRAQLLRYTEDSEGR-MTMAFKDLKL----VNDQIILVTPVTI 253
Query: 280 SHEINQQSPFWEISKAQLPKEELEIVVILEGMVEATGMTCQARSSYITSEILWGYRFTPV 339
HEI+ +SP + + + + K+ EI+V ++TG + Q+RSSY+ EILWG+RF V
Sbjct: 254 VHEIDHESPLYALDRKAVAKDNFEILVTFIYTGDSTGTSHQSRSSYVPREILWGHRFNDV 313
Query: 340 LTLEDGFYEVDYNSFHETYETSTPSLSAKEL 370
L ++ +Y+V+ F + E P SAK+L
Sbjct: 314 LEVKRKYYKVNCLQFEGSVEVYAPFCSAKQL 344
>gi|25121966 potassium inwardly-rectifying channel, subfamily J,
member 10 [Homo sapiens]
Length = 379
Score = 269 bits (687), Expect = 4e-72
Identities = 136/346 (39%), Positives = 214/346 (61%), Gaps = 8/346 (2%)
Query: 54 QRYVRKDGKCNVHHGNVRET-YRYLTDIFTTLVDLKWRFNLLIFVMVYTVTWLFFGMIWW 112
+R + KDG+ NV ++ + + YL D++TT +D++WR+ LL+F + TW FG++W+
Sbjct: 28 RRVLTKDGRSNVRMEHIADKRFLYLKDLWTTFIDMQWRYKLLLFSATFAGTWFLFGVVWY 87
Query: 113 LIAYIRGDMDHIEDPS-WTPCVTNLNGFVSAFLFSIETETTIGYGYRVITDKCPEGIILL 171
L+A GD+ ++ P+ TPCV ++ AFLFS+E++TTIGYG+R I+++CP I+LL
Sbjct: 88 LVAVAHGDLLELDPPANHTPCVVQVHTLTGAFLFSLESQTTIGYGFRYISEECPLAIVLL 147
Query: 172 LIQSVLGSIVNAFMVGCMFVKISQPKKRAETLVFSTHAVISMRDGKLCLMFRVGDLRNSH 231
+ Q VL +I+ F+ G KI++PKKRAET+ FS HAV++ +GK CLM RV ++R S
Sbjct: 148 IAQLVLTTILEIFITGTFLAKIARPKKRAETIRFSQHAVVASHNGKPCLMIRVANMRKSL 207
Query: 232 IVEASIRAKLIKSKQTSEGEFIPLNQTDINVGYYTGDDRLFLVSPLIISHEINQQSPFWE 291
++ + KL+++ QT EGE I LNQ ++ T D FL+ PL H +++ SP +
Sbjct: 208 LIGCQVTGKLLQTHQTKEGENIRLNQVNVTFQVDTASDSPFLILPLTFYHVVDETSPLKD 267
Query: 292 ISKAQLPKEELEIVVILEGMVEATGMTCQARSSYITSEILWGYRFTPVLTLE-DGFYEVD 350
+ + + + E+V+IL G VE+T TCQ R+SY+ EILWGY FTP ++L G Y D
Sbjct: 268 L-PLRSGEGDFELVLILSGTVESTSATCQVRTSYLPEEILWGYEFTPAISLSASGKYIAD 326
Query: 351 YNSFHETYETSTPSLSAKELAELASRAELPLSWSVSSKLNQHAELE 396
++ F + + ++PS L + R P + L + AE E
Sbjct: 327 FSLFDQVVKVASPS----GLRDSTVRYGDPEKLKLEESLREQAEKE 368
>gi|21361127 potassium inwardly-rectifying channel J15 [Homo
sapiens]
Length = 375
Score = 252 bits (644), Expect = 4e-67
Identities = 125/320 (39%), Positives = 200/320 (62%), Gaps = 3/320 (0%)
Query: 40 LPRHISRDRTKRKIQRYVRKDGKCNVHHGNVRETYR-YLTDIFTTLVDLKWRFNLLIFVM 98
L +H + K R + K G NV V Y YL D++TT++D+KWR+ L +F
Sbjct: 13 LVKHTAGAGLKANRPRVMSKSGHSNVRIDKVDGIYLLYLQDLWTTVIDMKWRYKLTLFAA 72
Query: 99 VYTVTWLFFGMIWWLIAYIRGDMDHIEDPS-WTPCVTNLNGFVSAFLFSIETETTIGYGY 157
+ +TW FG+I++ IA+I GD++ E S TPC+ ++ AFLFS+E++TTIGYG
Sbjct: 73 TFVMTWFLFGVIYYAIAFIHGDLEPGEPISNHTPCIMKVDSLTGAFLFSLESQTTIGYGV 132
Query: 158 RVITDKCPEGIILLLIQSVLGSIVNAFMVGCMFVKISQPKKRAETLVFSTHAVISMRDGK 217
R IT++CP I LL+ Q V+ +++ F+ G KI++PKKRAET+ FS AVI+ ++GK
Sbjct: 133 RSITEECPHAIFLLVAQLVITTLIEIFITGTFLAKIARPKKRAETIKFSHCAVITKQNGK 192
Query: 218 LCLMFRVGDLRNSHIVEASIRAKLIKSKQTSEGEFIPLNQTDINVGYYTGDDRLFLVSPL 277
LCL+ +V ++R S +++ + KL+++ T EGE I LNQ + + + FL+ P+
Sbjct: 193 LCLVIQVANMRKSLLIQCQLSGKLLQTHVTKEGERILLNQATVKFHVDSSSESPFLILPM 252
Query: 278 IISHEINQQSPFWEISKAQLPKEELEIVVILEGMVEATGMTCQARSSYITSEILWGYRFT 337
H +++ SP +++ L ++E E+VV+L VE+T CQ+R+SYI EI WG+ F
Sbjct: 253 TFYHVLDETSPLRDLTPQNLKEKEFELVVLLNATVESTSAVCQSRTSYIPEEIYWGFEFV 312
Query: 338 PVLTL-EDGFYEVDYNSFHE 356
PV++L ++G Y D++ F +
Sbjct: 313 PVVSLSKNGKYVADFSQFEQ 332
>gi|25777640 potassium inwardly-rectifying channel J15 [Homo
sapiens]
Length = 375
Score = 252 bits (644), Expect = 4e-67
Identities = 125/320 (39%), Positives = 200/320 (62%), Gaps = 3/320 (0%)
Query: 40 LPRHISRDRTKRKIQRYVRKDGKCNVHHGNVRETYR-YLTDIFTTLVDLKWRFNLLIFVM 98
L +H + K R + K G NV V Y YL D++TT++D+KWR+ L +F
Sbjct: 13 LVKHTAGAGLKANRPRVMSKSGHSNVRIDKVDGIYLLYLQDLWTTVIDMKWRYKLTLFAA 72
Query: 99 VYTVTWLFFGMIWWLIAYIRGDMDHIEDPS-WTPCVTNLNGFVSAFLFSIETETTIGYGY 157
+ +TW FG+I++ IA+I GD++ E S TPC+ ++ AFLFS+E++TTIGYG
Sbjct: 73 TFVMTWFLFGVIYYAIAFIHGDLEPGEPISNHTPCIMKVDSLTGAFLFSLESQTTIGYGV 132
Query: 158 RVITDKCPEGIILLLIQSVLGSIVNAFMVGCMFVKISQPKKRAETLVFSTHAVISMRDGK 217
R IT++CP I LL+ Q V+ +++ F+ G KI++PKKRAET+ FS AVI+ ++GK
Sbjct: 133 RSITEECPHAIFLLVAQLVITTLIEIFITGTFLAKIARPKKRAETIKFSHCAVITKQNGK 192
Query: 218 LCLMFRVGDLRNSHIVEASIRAKLIKSKQTSEGEFIPLNQTDINVGYYTGDDRLFLVSPL 277
LCL+ +V ++R S +++ + KL+++ T EGE I LNQ + + + FL+ P+
Sbjct: 193 LCLVIQVANMRKSLLIQCQLSGKLLQTHVTKEGERILLNQATVKFHVDSSSESPFLILPM 252
Query: 278 IISHEINQQSPFWEISKAQLPKEELEIVVILEGMVEATGMTCQARSSYITSEILWGYRFT 337
H +++ SP +++ L ++E E+VV+L VE+T CQ+R+SYI EI WG+ F
Sbjct: 253 TFYHVLDETSPLRDLTPQNLKEKEFELVVLLNATVESTSAVCQSRTSYIPEEIYWGFEFV 312
Query: 338 PVLTL-EDGFYEVDYNSFHE 356
PV++L ++G Y D++ F +
Sbjct: 313 PVVSLSKNGKYVADFSQFEQ 332
>gi|25777638 potassium inwardly-rectifying channel J15 [Homo
sapiens]
Length = 375
Score = 252 bits (644), Expect = 4e-67
Identities = 125/320 (39%), Positives = 200/320 (62%), Gaps = 3/320 (0%)
Query: 40 LPRHISRDRTKRKIQRYVRKDGKCNVHHGNVRETYR-YLTDIFTTLVDLKWRFNLLIFVM 98
L +H + K R + K G NV V Y YL D++TT++D+KWR+ L +F
Sbjct: 13 LVKHTAGAGLKANRPRVMSKSGHSNVRIDKVDGIYLLYLQDLWTTVIDMKWRYKLTLFAA 72
Query: 99 VYTVTWLFFGMIWWLIAYIRGDMDHIEDPS-WTPCVTNLNGFVSAFLFSIETETTIGYGY 157
+ +TW FG+I++ IA+I GD++ E S TPC+ ++ AFLFS+E++TTIGYG
Sbjct: 73 TFVMTWFLFGVIYYAIAFIHGDLEPGEPISNHTPCIMKVDSLTGAFLFSLESQTTIGYGV 132
Query: 158 RVITDKCPEGIILLLIQSVLGSIVNAFMVGCMFVKISQPKKRAETLVFSTHAVISMRDGK 217
R IT++CP I LL+ Q V+ +++ F+ G KI++PKKRAET+ FS AVI+ ++GK
Sbjct: 133 RSITEECPHAIFLLVAQLVITTLIEIFITGTFLAKIARPKKRAETIKFSHCAVITKQNGK 192
Query: 218 LCLMFRVGDLRNSHIVEASIRAKLIKSKQTSEGEFIPLNQTDINVGYYTGDDRLFLVSPL 277
LCL+ +V ++R S +++ + KL+++ T EGE I LNQ + + + FL+ P+
Sbjct: 193 LCLVIQVANMRKSLLIQCQLSGKLLQTHVTKEGERILLNQATVKFHVDSSSESPFLILPM 252
Query: 278 IISHEINQQSPFWEISKAQLPKEELEIVVILEGMVEATGMTCQARSSYITSEILWGYRFT 337
H +++ SP +++ L ++E E+VV+L VE+T CQ+R+SYI EI WG+ F
Sbjct: 253 TFYHVLDETSPLRDLTPQNLKEKEFELVVLLNATVESTSAVCQSRTSYIPEEIYWGFEFV 312
Query: 338 PVLTL-EDGFYEVDYNSFHE 356
PV++L ++G Y D++ F +
Sbjct: 313 PVVSLSKNGKYVADFSQFEQ 332
>gi|156119627 potassium inwardly-rectifying channel J13 [Homo
sapiens]
Length = 360
Score = 183 bits (464), Expect = 3e-46
Identities = 108/321 (33%), Positives = 174/321 (54%), Gaps = 9/321 (2%)
Query: 51 RKIQRYVRKDGKCNVHHGNVRETYRYLTDIFTTLVDLKWRFNLLIFVMVYTVTWLFFGMI 110
++ +R V KDG + + YL D + L+D++WR+ +L+F + V WL F ++
Sbjct: 15 QRYRRMVTKDGHSTLQMDGAQRGLAYLRDAWGILMDMRWRWMMLVFSASFVVHWLVFAVL 74
Query: 111 WWLIAYIRGDM--DHIEDP-SWTPCVTNLNGFVSAFLFSIETETTIGYGYRVITDKCPEG 167
W+++A + GD+ DH P + T CV + F +AF FS+ET+ TIGYG + CP
Sbjct: 75 WYVLAEMNGDLELDHDAPPENHTICVKYITSFTAAFSFSLETQLTIGYGTMFPSGDCPSA 134
Query: 168 IILLLIQSVLGSIVNAFMVGCMFVKISQPKKRAETLVFSTHAVISMRDGKLCLMFRVGDL 227
I LL IQ +LG ++ AF+ G KI++PK RA ++ F+ AV++ DGK L+F+V +
Sbjct: 135 IALLAIQMLLGLMLEAFITGAFVAKIARPKNRAFSIRFTDTAVVAHMDGKPNLIFQVANT 194
Query: 228 RNSHIVEASIRAKLIKSKQTSEGEFIPLNQTDINVGYYTGDDRLFLVSPLIISHEINQQS 287
R S + + A L + ++ + + D ++ + D+ F + PL H I S
Sbjct: 195 RPSPLTSVRVSAVLYQERENGK---LYQTSVDFHLDGISSDECPFFIFPLTYYHSITPSS 251
Query: 288 PFWEISKAQLPKEELEIVVILEGMVEATGMTCQARSSYITSEILWGYRFTPVLTL-EDGF 346
P + + + P E+VV L M E TG CQ R+SY+ SEI+ + F +LT G
Sbjct: 252 PLATLLQHENP-SHFELVVFLSAMQEGTGEICQRRTSYLPSEIMLHHCFASLLTRGSKGE 310
Query: 347 YEVDYNSFHETY-ETSTPSLS 366
Y++ +F +T E TP +S
Sbjct: 311 YQIKMENFDKTVPEFPTPLVS 331
>gi|41872577 raft-linking protein [Homo sapiens]
Length = 578
Score = 31.6 bits (70), Expect = 1.4
Identities = 13/29 (44%), Positives = 20/29 (68%)
Query: 388 KLNQHAELETEEEEKNLEEQTERNGDVAN 416
KL+ + + EE EKNLE+Q+ + GD+ N
Sbjct: 465 KLSARDKQQAEENEKNLEDQSSKAGDMGN 493
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.135 0.398
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 14,702,159
Number of Sequences: 37866
Number of extensions: 608731
Number of successful extensions: 2875
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 30
Number of HSP's successfully gapped in prelim test: 10
Number of HSP's that attempted gapping in prelim test: 2763
Number of HSP's gapped (non-prelim): 50
length of query: 423
length of database: 18,247,518
effective HSP length: 105
effective length of query: 318
effective length of database: 14,271,588
effective search space: 4538364984
effective search space used: 4538364984
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.