BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|4504839 potassium inwardly-rectifying channel J3 [Homo sapiens] (501 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|4504839 potassium inwardly-rectifying channel J3 [Homo sapiens] 1006 0.0 gi|4504843 potassium inwardly-rectifying channel J6 [Homo sapiens] 452 e-127 gi|24797141 potassium inwardly-rectifying channel J5 [Homo sapiens] 450 e-126 gi|25121970 potassium inwardly-rectifying channel subfamily J9 [... 440 e-123 gi|4504835 potassium inwardly-rectifying channel J2 [Homo sapiens] 379 e-105 gi|23110982 potassium inwardly-rectifying channel, subfamily J, ... 372 e-103 gi|239758082 PREDICTED: similar to thyrotoxic periodic paralysis... 366 e-101 gi|4826798 potassium inwardly-rectifying channel J4 [Homo sapiens] 358 8e-99 gi|23110984 potassium inwardly-rectifying channel J4 [Homo sapiens] 358 8e-99 gi|239757993 PREDICTED: similar to inward rectifying K+ channel ... 354 9e-98 gi|239757991 PREDICTED: similar to inward rectifying K+ channel ... 354 9e-98 gi|239751249 PREDICTED: hypothetical protein XP_002347768 [Homo ... 354 9e-98 gi|7019439 potassium inwardly-rectifying channel J14 [Homo sapiens] 343 2e-94 gi|25777635 potassium inwardly-rectifying channel J14 [Homo sapi... 343 2e-94 gi|62388888 potassium inwardly-rectifying channel J11 [Homo sapi... 330 2e-90 gi|4826802 potassium inwardly-rectifying channel J8 [Homo sapiens] 329 3e-90 gi|24497471 potassium inwardly-rectifying channel J1 isoform b [... 311 7e-85 gi|24497467 potassium inwardly-rectifying channel J1 isoform b [... 311 7e-85 gi|4504837 potassium inwardly-rectifying channel J1 isoform a [H... 311 7e-85 gi|148539892 potassium inwardly-rectifying channel J1 isoform b ... 311 7e-85 gi|24497473 potassium inwardly-rectifying channel J1 isoform b [... 311 7e-85 gi|25121966 potassium inwardly-rectifying channel, subfamily J, ... 273 3e-73 gi|8923823 potassium inwardly-rectifying channel J16 [Homo sapiens] 268 7e-72 gi|25777630 potassium inwardly-rectifying channel J16 [Homo sapi... 268 7e-72 gi|25777628 potassium inwardly-rectifying channel J16 [Homo sapi... 268 7e-72 gi|21361127 potassium inwardly-rectifying channel J15 [Homo sapi... 253 3e-67 gi|25777640 potassium inwardly-rectifying channel J15 [Homo sapi... 253 3e-67 gi|25777638 potassium inwardly-rectifying channel J15 [Homo sapi... 253 3e-67 gi|156119627 potassium inwardly-rectifying channel J13 [Homo sap... 179 7e-45 gi|148806865 zinc finger protein 492 [Homo sapiens] 33 0.46 >gi|4504839 potassium inwardly-rectifying channel J3 [Homo sapiens] Length = 501 Score = 1006 bits (2602), Expect = 0.0 Identities = 501/501 (100%), Positives = 501/501 (100%) Query: 1 MSALRRKFGDDYQVVTTSSSGSGLQPQGPGQDPQQQLVPKKKRQRFVDKNGRCNVQHGNL 60 MSALRRKFGDDYQVVTTSSSGSGLQPQGPGQDPQQQLVPKKKRQRFVDKNGRCNVQHGNL Sbjct: 1 MSALRRKFGDDYQVVTTSSSGSGLQPQGPGQDPQQQLVPKKKRQRFVDKNGRCNVQHGNL 60 Query: 61 GSETSRYLSDLFTTLVDLKWRWNLFIFILTYTVAWLFMASMWWVIAYTRGDLNKAHVGNY 120 GSETSRYLSDLFTTLVDLKWRWNLFIFILTYTVAWLFMASMWWVIAYTRGDLNKAHVGNY Sbjct: 61 GSETSRYLSDLFTTLVDLKWRWNLFIFILTYTVAWLFMASMWWVIAYTRGDLNKAHVGNY 120 Query: 121 TPCVANVYNFPSAFLFFIETEATIGYGYRYITDKCPEGIILFLFQSILGSIVDAFLIGCM 180 TPCVANVYNFPSAFLFFIETEATIGYGYRYITDKCPEGIILFLFQSILGSIVDAFLIGCM Sbjct: 121 TPCVANVYNFPSAFLFFIETEATIGYGYRYITDKCPEGIILFLFQSILGSIVDAFLIGCM 180 Query: 181 FIKMSQPKKRAETLMFSEHAVISMRDGKLTLMFRVGNLRNSHMVSAQIRCKLLKSRQTPE 240 FIKMSQPKKRAETLMFSEHAVISMRDGKLTLMFRVGNLRNSHMVSAQIRCKLLKSRQTPE Sbjct: 181 FIKMSQPKKRAETLMFSEHAVISMRDGKLTLMFRVGNLRNSHMVSAQIRCKLLKSRQTPE 240 Query: 241 GEFLPLDQLELDVGFSTGADQLFLVSPLTICHVIDAKSPFYDLSQRSMQTEQFEIVVILE 300 GEFLPLDQLELDVGFSTGADQLFLVSPLTICHVIDAKSPFYDLSQRSMQTEQFEIVVILE Sbjct: 241 GEFLPLDQLELDVGFSTGADQLFLVSPLTICHVIDAKSPFYDLSQRSMQTEQFEIVVILE 300 Query: 301 GIVETTGMTCQARTSYTEDEVLWGHRFFPVISLEEGFFKVDYSQFHATFEVPTPPYSVKE 360 GIVETTGMTCQARTSYTEDEVLWGHRFFPVISLEEGFFKVDYSQFHATFEVPTPPYSVKE Sbjct: 301 GIVETTGMTCQARTSYTEDEVLWGHRFFPVISLEEGFFKVDYSQFHATFEVPTPPYSVKE 360 Query: 361 QEEMLLMSSPLIAPAITNSKERHNSVECLDGLDDITTKLPSKLQKITGREDFPKKLLRMS 420 QEEMLLMSSPLIAPAITNSKERHNSVECLDGLDDITTKLPSKLQKITGREDFPKKLLRMS Sbjct: 361 QEEMLLMSSPLIAPAITNSKERHNSVECLDGLDDITTKLPSKLQKITGREDFPKKLLRMS 420 Query: 421 STTSEKAYSLGDLPMKLQRISSVPGNSEEKLVSKTTKMLSDPMSQSVADLPPKLQKMAGG 480 STTSEKAYSLGDLPMKLQRISSVPGNSEEKLVSKTTKMLSDPMSQSVADLPPKLQKMAGG Sbjct: 421 STTSEKAYSLGDLPMKLQRISSVPGNSEEKLVSKTTKMLSDPMSQSVADLPPKLQKMAGG 480 Query: 481 AARMEGNLPAKLRKMNSDRFT 501 AARMEGNLPAKLRKMNSDRFT Sbjct: 481 AARMEGNLPAKLRKMNSDRFT 501 >gi|4504843 potassium inwardly-rectifying channel J6 [Homo sapiens] Length = 423 Score = 452 bits (1162), Expect = e-127 Identities = 213/348 (61%), Positives = 277/348 (79%), Gaps = 1/348 (0%) Query: 40 KKKRQRFVDKNGRCNVQHGNLGSETSRYLSDLFTTLVDLKWRWNLFIFILTYTVAWLFMA 99 K+K QR+V K+G+CNV HGN+ ET RYL+D+FTTLVDLKWR+NL IF++ YTV WLF Sbjct: 50 KRKIQRYVRKDGKCNVHHGNV-RETYRYLTDIFTTLVDLKWRFNLLIFVMVYTVTWLFFG 108 Query: 100 SMWWVIAYTRGDLNKAHVGNYTPCVANVYNFPSAFLFFIETEATIGYGYRYITDKCPEGI 159 +WW+IAY RGD++ ++TPCV N+ F SAFLF IETE TIGYGYR ITDKCPEGI Sbjct: 109 MIWWLIAYIRGDMDHIEDPSWTPCVTNLNGFVSAFLFSIETETTIGYGYRVITDKCPEGI 168 Query: 160 ILFLFQSILGSIVDAFLIGCMFIKMSQPKKRAETLMFSEHAVISMRDGKLTLMFRVGNLR 219 IL L QS+LGSIV+AF++GCMF+K+SQPKKRAETL+FS HAVISMRDGKL LMFRVG+LR Sbjct: 169 ILLLIQSVLGSIVNAFMVGCMFVKISQPKKRAETLVFSTHAVISMRDGKLCLMFRVGDLR 228 Query: 220 NSHMVSAQIRCKLLKSRQTPEGEFLPLDQLELDVGFSTGADQLFLVSPLTICHVIDAKSP 279 NSH+V A IR KL+KS+QT EGEF+PL+Q +++VG+ TG D+LFLVSPL I H I+ +SP Sbjct: 229 NSHIVEASIRAKLIKSKQTSEGEFIPLNQTDINVGYYTGDDRLFLVSPLIISHEINQQSP 288 Query: 280 FYDLSQRSMQTEQFEIVVILEGIVETTGMTCQARTSYTEDEVLWGHRFFPVISLEEGFFK 339 F+++S+ + E+ EIVVILEG+VE TGMTCQAR+SY E+LWG+RF PV++LE+GF++ Sbjct: 289 FWEISKAQLPKEELEIVVILEGMVEATGMTCQARSSYITSEILWGYRFTPVLTLEDGFYE 348 Query: 340 VDYSQFHATFEVPTPPYSVKEQEEMLLMSSPLIAPAITNSKERHNSVE 387 VDY+ FH T+E TP S KE E+ + ++ ++++ +H +E Sbjct: 349 VDYNSFHETYETSTPSLSAKELAELASRAELPLSWSVSSKLNQHAELE 396 >gi|24797141 potassium inwardly-rectifying channel J5 [Homo sapiens] Length = 419 Score = 450 bits (1158), Expect = e-126 Identities = 218/327 (66%), Positives = 268/327 (81%), Gaps = 5/327 (1%) Query: 40 KKKRQRFVDKNGRCNVQHGNLGSETSRYLSDLFTTLVDLKWRWNLFIFILTYTVAWLFMA 99 KK RQR+++K+G+CNV HGN+ ET RYLSDLFTTLVDLKWR+NL +F + YTV WLF Sbjct: 47 KKPRQRYMEKSGKCNVHHGNV-QETYRYLSDLFTTLVDLKWRFNLLVFTMVYTVTWLFFG 105 Query: 100 SMWWVIAYTRGDLNKAHVGN--YTPCVANVYNFPSAFLFFIETEATIGYGYRYITDKCPE 157 +WW+IAY RGDL+ HVG+ + PCV N+ F SAFLF IETE TIGYG+R IT+KCPE Sbjct: 106 FIWWLIAYIRGDLD--HVGDQEWIPCVENLSGFVSAFLFSIETETTIGYGFRVITEKCPE 163 Query: 158 GIILFLFQSILGSIVDAFLIGCMFIKMSQPKKRAETLMFSEHAVISMRDGKLTLMFRVGN 217 GIIL L Q+ILGSIV+AF++GCMF+K+SQPKKRAETLMFS +AVISMRD KL LMFRVG+ Sbjct: 164 GIILLLVQAILGSIVNAFMVGCMFVKISQPKKRAETLMFSNNAVISMRDEKLCLMFRVGD 223 Query: 218 LRNSHMVSAQIRCKLLKSRQTPEGEFLPLDQLELDVGFSTGADQLFLVSPLTICHVIDAK 277 LRNSH+V A IR KL+KSRQT EGEF+PL+Q +++VGF TG D+LFLVSPL I H I+ K Sbjct: 224 LRNSHIVEASIRAKLIKSRQTKEGEFIPLNQTDINVGFDTGDDRLFLVSPLIISHEINQK 283 Query: 278 SPFYDLSQRSMQTEQFEIVVILEGIVETTGMTCQARTSYTEDEVLWGHRFFPVISLEEGF 337 SPF+++SQ + E+FE+VVILEG+VE TGMTCQAR+SY + EVLWGHRF PV++LE+GF Sbjct: 284 SPFWEMSQAQLHQEEFEVVVILEGMVEATGMTCQARSSYMDTEVLWGHRFTPVLTLEKGF 343 Query: 338 FKVDYSQFHATFEVPTPPYSVKEQEEM 364 ++VDY+ FH T+E TP KE EM Sbjct: 344 YEVDYNTFHDTYETNTPSCCAKELAEM 370 >gi|25121970 potassium inwardly-rectifying channel subfamily J9 [Homo sapiens] Length = 393 Score = 440 bits (1132), Expect = e-123 Identities = 210/332 (63%), Positives = 267/332 (80%), Gaps = 2/332 (0%) Query: 33 PQQQLVPKKK-RQRFVDKNGRCNVQHGNLGSETSRYLSDLFTTLVDLKWRWNLFIFILTY 91 P Q+ P+++ RQR+V+K+GRCNVQ GN+ ET RYL+DLFTTLVDL+WR +L F+L Y Sbjct: 10 PGQEEPPRRRGRQRYVEKDGRCNVQQGNV-RETYRYLTDLFTTLVDLQWRLSLLFFVLAY 68 Query: 92 TVAWLFMASMWWVIAYTRGDLNKAHVGNYTPCVANVYNFPSAFLFFIETEATIGYGYRYI 151 + WLF ++WW+IAY RGDL +TPCV N+ F +AFLF IETE TIGYG+R I Sbjct: 69 ALTWLFFGAIWWLIAYGRGDLEHLEDTAWTPCVNNLNGFVAAFLFSIETETTIGYGHRVI 128 Query: 152 TDKCPEGIILFLFQSILGSIVDAFLIGCMFIKMSQPKKRAETLMFSEHAVISMRDGKLTL 211 TD+CPEGI+L L Q+ILGS+V+AF++GCMF+K+SQP KRA TL+FS HAV+S+RDG+L L Sbjct: 129 TDQCPEGIVLLLLQAILGSMVNAFMVGCMFVKISQPNKRAATLVFSSHAVVSLRDGRLCL 188 Query: 212 MFRVGNLRNSHMVSAQIRCKLLKSRQTPEGEFLPLDQLELDVGFSTGADQLFLVSPLTIC 271 MFRVG+LR+SH+V A IR KL++SRQT EGEF+PL Q +L VGF TG D+LFLVSPL I Sbjct: 189 MFRVGDLRSSHIVEASIRAKLIRSRQTLEGEFIPLHQTDLSVGFDTGDDRLFLVSPLVIS 248 Query: 272 HVIDAKSPFYDLSQRSMQTEQFEIVVILEGIVETTGMTCQARTSYTEDEVLWGHRFFPVI 331 H IDA SPF++ S+R+++ + FEIVVILEG+VE TGMTCQAR+SY DEVLWGHRF V+ Sbjct: 249 HEIDAASPFWEASRRALERDDFEIVVILEGMVEATGMTCQARSSYLVDEVLWGHRFTSVL 308 Query: 332 SLEEGFFKVDYSQFHATFEVPTPPYSVKEQEE 363 +LE+GF++VDY+ FH TFEVPTP S +E E Sbjct: 309 TLEDGFYEVDYASFHETFEVPTPSCSARELAE 340 >gi|4504835 potassium inwardly-rectifying channel J2 [Homo sapiens] Length = 427 Score = 379 bits (973), Expect = e-105 Identities = 182/348 (52%), Positives = 250/348 (71%), Gaps = 6/348 (1%) Query: 12 YQVVTTSSSGSGLQPQ----GPGQDPQQQLVPKKKRQRFVDKNGRCNVQHGNLGSETSRY 67 Y +V++ G L G G + ++ R RFV K+G CNVQ N+G + RY Sbjct: 9 YSIVSSEEDGMKLATMAVANGFGNGKSKVHTRQQCRSRFVKKDGHCNVQFINVGEKGQRY 68 Query: 68 LSDLFTTLVDLKWRWNLFIFILTYTVAWLFMASMWWVIAYTRGDLNKAHVGNYTPCVANV 127 L+D+FTT VD++WRW L IF L + ++WLF ++W+IA GDL+ + G CV+ V Sbjct: 69 LADIFTTCVDIRWRWMLVIFCLAFVLSWLFFGCVFWLIALLHGDLDASKEGK--ACVSEV 126 Query: 128 YNFPSAFLFFIETEATIGYGYRYITDKCPEGIILFLFQSILGSIVDAFLIGCMFIKMSQP 187 +F +AFLF IET+ TIGYG+R +TD+CP + + +FQSI+G I+DAF+IG + KM++P Sbjct: 127 NSFTAAFLFSIETQTTIGYGFRCVTDECPIAVFMVVFQSIVGCIIDAFIIGAVMAKMAKP 186 Query: 188 KKRAETLMFSEHAVISMRDGKLTLMFRVGNLRNSHMVSAQIRCKLLKSRQTPEGEFLPLD 247 KKR ETL+FS +AVI+MRDGKL LM+RVGNLR SH+V A +R +LLKSR T EGE++PLD Sbjct: 187 KKRNETLVFSHNAVIAMRDGKLCLMWRVGNLRKSHLVEAHVRAQLLKSRITSEGEYIPLD 246 Query: 248 QLELDVGFSTGADQLFLVSPLTICHVIDAKSPFYDLSQRSMQTEQFEIVVILEGIVETTG 307 Q++++VGF +G D++FLVSP+TI H ID SP YDLS++ + FEIVVILEG+VE T Sbjct: 247 QIDINVGFDSGIDRIFLVSPITIVHEIDEDSPLYDLSKQDIDNADFEIVVILEGMVEATA 306 Query: 308 MTCQARTSYTEDEVLWGHRFFPVISLEEGFFKVDYSQFHATFEVPTPP 355 MT Q R+SY +E+LWGHR+ PV+ E+ ++KVDYS+FH T+EVP P Sbjct: 307 MTTQCRSSYLANEILWGHRYEPVLFEEKHYYKVDYSRFHKTYEVPNTP 354 >gi|23110982 potassium inwardly-rectifying channel, subfamily J, member 12 [Homo sapiens] Length = 433 Score = 372 bits (955), Expect = e-103 Identities = 172/325 (52%), Positives = 241/325 (74%), Gaps = 1/325 (0%) Query: 40 KKKRQRFVDKNGRCNVQHGNLGSETSRYLSDLFTTLVDLKWRWNLFIFILTYTVAWLFMA 99 ++ R RFV KNG+CN++ N+ ++ RYL+D+FTT VD++WR+ L IF L + +WL Sbjct: 40 RRCRNRFVKKNGQCNIEFANMDEKSQRYLADMFTTCVDIRWRYMLLIFSLAFLASWLLFG 99 Query: 100 SMWWVIAYTRGDLNKAHVGNYTPCVANVYNFPSAFLFFIETEATIGYGYRYITDKCPEGI 159 ++WVIA GDL A TPCV V+ F +AFLF IET+ TIGYG R +T++CP + Sbjct: 100 IIFWVIAVAHGDLEPAEGRGRTPCVMQVHGFMAAFLFSIETQTTIGYGLRCVTEECPVAV 159 Query: 160 ILFLFQSILGSIVDAFLIGCMFIKMSQPKKRAETLMFSEHAVISMRDGKLTLMFRVGNLR 219 + + QSI+G I+D+F+IG + KM++PKKRA+TL+FS +AV+++RDGKL LM+RVGNLR Sbjct: 160 FMVVAQSIVGCIIDSFMIGAIMAKMARPKKRAQTLLFSHNAVVALRDGKLCLMWRVGNLR 219 Query: 220 NSHMVSAQIRCKLLKSRQTPEGEFLPLDQLELDVGFSTGADQLFLVSPLTICHVIDAKSP 279 SH+V A +R +L+K R T EGE++PLDQ+++DVGF G D++FLVSP+TI H ID SP Sbjct: 220 KSHIVEAHVRAQLIKPRVTEEGEYIPLDQIDIDVGFDKGLDRIFLVSPITILHEIDEASP 279 Query: 280 FYDLSQRSMQTEQFEIVVILEGIVETTGMTCQARTSYTEDEVLWGHRFFPVISLEEGFFK 339 + +S++ ++T+ FEIVVILEG+VE T MT QAR+SY +E+LWGHRF PV+ E+ +K Sbjct: 280 LFGISRQDLETDDFEIVVILEGMVEATAMTTQARSSYLANEILWGHRFEPVLFEEKNQYK 339 Query: 340 VDYSQFHATFEVP-TPPYSVKEQEE 363 +DYS FH T+EVP TP S K+ E Sbjct: 340 IDYSHFHKTYEVPSTPRCSAKDLVE 364 >gi|239758082 PREDICTED: similar to thyrotoxic periodic paralysis susceptibility ion channel [Homo sapiens] Length = 433 Score = 366 bits (940), Expect = e-101 Identities = 171/325 (52%), Positives = 238/325 (73%), Gaps = 1/325 (0%) Query: 40 KKKRQRFVDKNGRCNVQHGNLGSETSRYLSDLFTTLVDLKWRWNLFIFILTYTVAWLFMA 99 ++ R RFV KNG+CN+ N+ ++ RYL+D+FTT VD++WR+ L IF L + +WL Sbjct: 40 RRCRNRFVKKNGQCNIAFANMDEKSQRYLADMFTTCVDIRWRYMLLIFSLAFLASWLLFG 99 Query: 100 SMWWVIAYTRGDLNKAHVGNYTPCVANVYNFPSAFLFFIETEATIGYGYRYITDKCPEGI 159 ++WVIA GDL A TPCV V+ F +AFLF IET+ TIGYG R +T++C + Sbjct: 100 VIFWVIAVAHGDLEPAEGHGRTPCVMQVHGFMAAFLFSIETQTTIGYGLRCVTEECLVAV 159 Query: 160 ILFLFQSILGSIVDAFLIGCMFIKMSQPKKRAETLMFSEHAVISMRDGKLTLMFRVGNLR 219 + + QSI+G I+D+F+IG + KM++PKKRA TL+FS +AV+++RDGKL LM+RVGNLR Sbjct: 160 FMVVAQSIVGCIIDSFMIGAIMAKMARPKKRAHTLLFSHNAVVALRDGKLCLMWRVGNLR 219 Query: 220 NSHMVSAQIRCKLLKSRQTPEGEFLPLDQLELDVGFSTGADQLFLVSPLTICHVIDAKSP 279 SH+V A +R +L+K R T EGE++PLDQ+++DVGF G D++FLVSP+TI H ID SP Sbjct: 220 KSHIVEAHVRAQLIKPRVTEEGEYIPLDQIDIDVGFDKGLDRIFLVSPITILHEIDEASP 279 Query: 280 FYDLSQRSMQTEQFEIVVILEGIVETTGMTCQARTSYTEDEVLWGHRFFPVISLEEGFFK 339 + +S++ ++T+ FEIVVILEG+VE T MT QAR+SY +E+LWGHRF PV+ E+ +K Sbjct: 280 LFGISRQDLETDDFEIVVILEGMVEATAMTTQARSSYLANEILWGHRFEPVLFEEKNQYK 339 Query: 340 VDYSQFHATFEVP-TPPYSVKEQEE 363 +DYS FH T+EVP TP S K+ E Sbjct: 340 IDYSHFHKTYEVPSTPRCSAKDLVE 364 >gi|4826798 potassium inwardly-rectifying channel J4 [Homo sapiens] Length = 445 Score = 358 bits (918), Expect = 8e-99 Identities = 177/364 (48%), Positives = 245/364 (67%), Gaps = 17/364 (4%) Query: 28 GPGQDPQQQLVPKKKRQRFVDKNGRCNVQHGNLGSETSRYLSDLFTTLVDLKWRWNLFIF 87 G ++ Q + +K+R RFV KNG+CNV NL +++ RY++D+FTT VD +WR+ L IF Sbjct: 3 GHSRNGQAHVPRRKRRNRFVKKNGQCNVYFANLSNKSQRYMADIFTTCVDTRWRYMLMIF 62 Query: 88 ILTYTVAWLFMASMWWVIAYTRGDLNK-----------AHVGNYTP-----CVANVYNFP 131 + V+WLF ++W IA+ GDL A G P C+ +V F Sbjct: 63 SAAFLVSWLFFGLLFWCIAFFHGDLEASPGVPAAGGPAAGGGGAAPVAPKPCIMHVNGFL 122 Query: 132 SAFLFFIETEATIGYGYRYITDKCPEGIILFLFQSILGSIVDAFLIGCMFIKMSQPKKRA 191 AFLF +ET+ TIGYG+R +T++CP +I + QSI+G ++D+F+IG + KM++PKKRA Sbjct: 123 GAFLFSVETQTTIGYGFRCVTEECPLAVIAVVVQSIVGCVIDSFMIGTIMAKMARPKKRA 182 Query: 192 ETLMFSEHAVISMRDGKLTLMFRVGNLRNSHMVSAQIRCKLLKSRQTPEGEFLPLDQLEL 251 +TL+FS HAVIS+RDGKL LM+RVGNLR SH+V A +R +L+K T EGE+LPLDQ +L Sbjct: 183 QTLLFSHHAVISVRDGKLCLMWRVGNLRKSHIVEAHVRAQLIKPYMTQEGEYLPLDQRDL 242 Query: 252 DVGFSTGADQLFLVSPLTICHVIDAKSPFYDLSQRSMQTEQFEIVVILEGIVETTGMTCQ 311 +VG+ G D++FLVSP+ I H ID SP Y + + +++E FEIVVILEG+VE T MT Q Sbjct: 243 NVGYDIGLDRIFLVSPIIIVHEIDEDSPLYGMGKEELESEDFEIVVILEGMVEATAMTTQ 302 Query: 312 ARTSYTEDEVLWGHRFFPVISLEEGFFKVDYSQFHATFEVP-TPPYSVKEQEEMLLMSSP 370 AR+SY E+LWGHRF PV+ E+ +KVDYS+FH T+EV TP S +E +E + P Sbjct: 303 ARSSYLASEILWGHRFEPVVFEEKSHYKVDYSRFHKTYEVAGTPCCSARELQESKITVLP 362 Query: 371 LIAP 374 P Sbjct: 363 APPP 366 >gi|23110984 potassium inwardly-rectifying channel J4 [Homo sapiens] Length = 445 Score = 358 bits (918), Expect = 8e-99 Identities = 177/364 (48%), Positives = 245/364 (67%), Gaps = 17/364 (4%) Query: 28 GPGQDPQQQLVPKKKRQRFVDKNGRCNVQHGNLGSETSRYLSDLFTTLVDLKWRWNLFIF 87 G ++ Q + +K+R RFV KNG+CNV NL +++ RY++D+FTT VD +WR+ L IF Sbjct: 3 GHSRNGQAHVPRRKRRNRFVKKNGQCNVYFANLSNKSQRYMADIFTTCVDTRWRYMLMIF 62 Query: 88 ILTYTVAWLFMASMWWVIAYTRGDLNK-----------AHVGNYTP-----CVANVYNFP 131 + V+WLF ++W IA+ GDL A G P C+ +V F Sbjct: 63 SAAFLVSWLFFGLLFWCIAFFHGDLEASPGVPAAGGPAAGGGGAAPVAPKPCIMHVNGFL 122 Query: 132 SAFLFFIETEATIGYGYRYITDKCPEGIILFLFQSILGSIVDAFLIGCMFIKMSQPKKRA 191 AFLF +ET+ TIGYG+R +T++CP +I + QSI+G ++D+F+IG + KM++PKKRA Sbjct: 123 GAFLFSVETQTTIGYGFRCVTEECPLAVIAVVVQSIVGCVIDSFMIGTIMAKMARPKKRA 182 Query: 192 ETLMFSEHAVISMRDGKLTLMFRVGNLRNSHMVSAQIRCKLLKSRQTPEGEFLPLDQLEL 251 +TL+FS HAVIS+RDGKL LM+RVGNLR SH+V A +R +L+K T EGE+LPLDQ +L Sbjct: 183 QTLLFSHHAVISVRDGKLCLMWRVGNLRKSHIVEAHVRAQLIKPYMTQEGEYLPLDQRDL 242 Query: 252 DVGFSTGADQLFLVSPLTICHVIDAKSPFYDLSQRSMQTEQFEIVVILEGIVETTGMTCQ 311 +VG+ G D++FLVSP+ I H ID SP Y + + +++E FEIVVILEG+VE T MT Q Sbjct: 243 NVGYDIGLDRIFLVSPIIIVHEIDEDSPLYGMGKEELESEDFEIVVILEGMVEATAMTTQ 302 Query: 312 ARTSYTEDEVLWGHRFFPVISLEEGFFKVDYSQFHATFEVP-TPPYSVKEQEEMLLMSSP 370 AR+SY E+LWGHRF PV+ E+ +KVDYS+FH T+EV TP S +E +E + P Sbjct: 303 ARSSYLASEILWGHRFEPVVFEEKSHYKVDYSRFHKTYEVAGTPCCSARELQESKITVLP 362 Query: 371 LIAP 374 P Sbjct: 363 APPP 366 >gi|239757993 PREDICTED: similar to inward rectifying K+ channel negative regulator Kir2.2v isoform 1 [Homo sapiens] Length = 432 Score = 354 bits (909), Expect = 9e-98 Identities = 172/355 (48%), Positives = 242/355 (68%), Gaps = 4/355 (1%) Query: 12 YQVVTTSSSGSGLQPQGPGQDPQQQLVPKKKR--QRFVDKNGRCNVQHGNLGSETSRYLS 69 Y +V++ G L V ++R RFV KNG+CN++ N+ ++ RYL+ Sbjct: 10 YSIVSSEEDGLHLVTMSGANGFGNGKVHTRRRCHNRFVKKNGQCNIEFANMDEKSQRYLA 69 Query: 70 DLFTTLVDLKWRWNLFIFILTYTVAWLFMASMWWVIAYTRGDLNKAHVGNYTPCVANVYN 129 D+FTT VD++WR+ L IF L + +WL ++WVIA GDL A TPCV V+ Sbjct: 70 DIFTTCVDIRWRYMLLIFSLAFLASWLLFGVIFWVIAVAHGDLEPAEGRGRTPCVMQVHG 129 Query: 130 FPSAFLFFIETEATIGYGYRYITDKCPEGIILFLFQSILGSIVDAFLIGCMFIKMSQPKK 189 F +AFLF I+T+ TI YG R +T++CP + + + QSI+G I+++F+IG + KM +PKK Sbjct: 130 FMAAFLFSIKTQNTISYGLRCVTEECPVAVFMVVAQSIVGCIINSFMIGAIMAKMVRPKK 189 Query: 190 RAETLMFSEHAVISMRDGKLTLMFRVGNLRNSHMVSAQIRCKLLKSRQTPEGEFLPLDQL 249 RA+TL+FS +AV+++RDGKL M+RVGNLR SH+V A +R +L+K R T EGE++PLDQ+ Sbjct: 190 RAQTLLFSHNAVVALRDGKLCFMWRVGNLRKSHIVEAHVRAQLIKPRVTKEGEYIPLDQI 249 Query: 250 ELDVGFSTGADQLFLVSPLTICHVIDAKSPFYDLSQRSMQTEQFEIVVILEGIVETTGMT 309 ++DVGF G D FLVSP+TI H ID SP + +S++ +Q + FEIV+ILEGIVE T MT Sbjct: 250 DIDVGFDKGLDHSFLVSPITILHEIDEASPLFGISRQDLQMDDFEIVIILEGIVEATAMT 309 Query: 310 CQARTSYTEDEVLWGHRFFPVISLEEGFFKVDYSQFHATFEVP-TPPYSVKEQEE 363 QAR+SY +E+LWGHRF PV+ E+ +K+DY FH T+EVP TP S K+ E Sbjct: 310 TQARSSYLANEILWGHRFEPVL-FEKNQYKIDYLHFHKTYEVPSTPRCSAKDLVE 363 >gi|239757991 PREDICTED: similar to inward rectifying K+ channel negative regulator Kir2.2v isoform 2 [Homo sapiens] Length = 534 Score = 354 bits (909), Expect = 9e-98 Identities = 172/355 (48%), Positives = 242/355 (68%), Gaps = 4/355 (1%) Query: 12 YQVVTTSSSGSGLQPQGPGQDPQQQLVPKKKR--QRFVDKNGRCNVQHGNLGSETSRYLS 69 Y +V++ G L V ++R RFV KNG+CN++ N+ ++ RYL+ Sbjct: 112 YSIVSSEEDGLHLVTMSGANGFGNGKVHTRRRCHNRFVKKNGQCNIEFANMDEKSQRYLA 171 Query: 70 DLFTTLVDLKWRWNLFIFILTYTVAWLFMASMWWVIAYTRGDLNKAHVGNYTPCVANVYN 129 D+FTT VD++WR+ L IF L + +WL ++WVIA GDL A TPCV V+ Sbjct: 172 DIFTTCVDIRWRYMLLIFSLAFLASWLLFGVIFWVIAVAHGDLEPAEGRGRTPCVMQVHG 231 Query: 130 FPSAFLFFIETEATIGYGYRYITDKCPEGIILFLFQSILGSIVDAFLIGCMFIKMSQPKK 189 F +AFLF I+T+ TI YG R +T++CP + + + QSI+G I+++F+IG + KM +PKK Sbjct: 232 FMAAFLFSIKTQNTISYGLRCVTEECPVAVFMVVAQSIVGCIINSFMIGAIMAKMVRPKK 291 Query: 190 RAETLMFSEHAVISMRDGKLTLMFRVGNLRNSHMVSAQIRCKLLKSRQTPEGEFLPLDQL 249 RA+TL+FS +AV+++RDGKL M+RVGNLR SH+V A +R +L+K R T EGE++PLDQ+ Sbjct: 292 RAQTLLFSHNAVVALRDGKLCFMWRVGNLRKSHIVEAHVRAQLIKPRVTKEGEYIPLDQI 351 Query: 250 ELDVGFSTGADQLFLVSPLTICHVIDAKSPFYDLSQRSMQTEQFEIVVILEGIVETTGMT 309 ++DVGF G D FLVSP+TI H ID SP + +S++ +Q + FEIV+ILEGIVE T MT Sbjct: 352 DIDVGFDKGLDHSFLVSPITILHEIDEASPLFGISRQDLQMDDFEIVIILEGIVEATAMT 411 Query: 310 CQARTSYTEDEVLWGHRFFPVISLEEGFFKVDYSQFHATFEVP-TPPYSVKEQEE 363 QAR+SY +E+LWGHRF PV+ E+ +K+DY FH T+EVP TP S K+ E Sbjct: 412 TQARSSYLANEILWGHRFEPVL-FEKNQYKIDYLHFHKTYEVPSTPRCSAKDLVE 465 >gi|239751249 PREDICTED: hypothetical protein XP_002347768 [Homo sapiens] Length = 432 Score = 354 bits (909), Expect = 9e-98 Identities = 172/355 (48%), Positives = 242/355 (68%), Gaps = 4/355 (1%) Query: 12 YQVVTTSSSGSGLQPQGPGQDPQQQLVPKKKR--QRFVDKNGRCNVQHGNLGSETSRYLS 69 Y +V++ G L V ++R RFV KNG+CN++ N+ ++ RYL+ Sbjct: 10 YSIVSSEEDGLHLVTMSGANGFGNGKVHTRRRCHNRFVKKNGQCNIEFANMDEKSQRYLA 69 Query: 70 DLFTTLVDLKWRWNLFIFILTYTVAWLFMASMWWVIAYTRGDLNKAHVGNYTPCVANVYN 129 D+FTT VD++WR+ L IF L + +WL ++WVIA GDL A TPCV V+ Sbjct: 70 DIFTTCVDIRWRYMLLIFSLAFLASWLLFGVIFWVIAVAHGDLEPAEGRGRTPCVMQVHG 129 Query: 130 FPSAFLFFIETEATIGYGYRYITDKCPEGIILFLFQSILGSIVDAFLIGCMFIKMSQPKK 189 F +AFLF I+T+ TI YG R +T++CP + + + QSI+G I+++F+IG + KM +PKK Sbjct: 130 FMAAFLFSIKTQNTISYGLRCVTEECPVAVFMVVAQSIVGCIINSFMIGAIMAKMVRPKK 189 Query: 190 RAETLMFSEHAVISMRDGKLTLMFRVGNLRNSHMVSAQIRCKLLKSRQTPEGEFLPLDQL 249 RA+TL+FS +AV+++RDGKL M+RVGNLR SH+V A +R +L+K R T EGE++PLDQ+ Sbjct: 190 RAQTLLFSHNAVVALRDGKLCFMWRVGNLRKSHIVEAHVRAQLIKPRVTKEGEYIPLDQI 249 Query: 250 ELDVGFSTGADQLFLVSPLTICHVIDAKSPFYDLSQRSMQTEQFEIVVILEGIVETTGMT 309 ++DVGF G D FLVSP+TI H ID SP + +S++ +Q + FEIV+ILEGIVE T MT Sbjct: 250 DIDVGFDKGLDHSFLVSPITILHEIDEASPLFGISRQDLQMDDFEIVIILEGIVEATAMT 309 Query: 310 CQARTSYTEDEVLWGHRFFPVISLEEGFFKVDYSQFHATFEVP-TPPYSVKEQEE 363 QAR+SY +E+LWGHRF PV+ E+ +K+DY FH T+EVP TP S K+ E Sbjct: 310 TQARSSYLANEILWGHRFEPVL-FEKNQYKIDYLHFHKTYEVPSTPRCSAKDLVE 363 >gi|7019439 potassium inwardly-rectifying channel J14 [Homo sapiens] Length = 436 Score = 343 bits (880), Expect = 2e-94 Identities = 176/366 (48%), Positives = 242/366 (66%), Gaps = 8/366 (2%) Query: 3 ALRRKFG----DDYQVVTTSSSGSGLQPQGPGQDPQQQLVPKKKRQRFVDKNGRCNVQHG 58 ALRR G D + +G GL G P Q V ++ R RFV K+G CNV+ Sbjct: 6 ALRRLSGALDSGDSRAGDEEEAGPGLCRNGWAPAPVQSPVGRR-RGRFVKKDGHCNVRFV 64 Query: 59 NLGSETSRYLSDLFTTLVDLKWRWNLFIFILTYTVAWLFMASMWWVIAYTRGDLNKAHVG 118 NLG + +RYLSDLFTT VD++WRW +F ++ +WL +W+IA GDL A Sbjct: 65 NLGGQGARYLSDLFTTCVDVRWRWMCLLFSCSFLASWLLFGLAFWLIASLHGDL--AAPP 122 Query: 119 NYTPCVANVYNFPSAFLFFIETEATIGYGYRYITDKCPEGIILFLFQSILGSIVDAFLIG 178 PC ++V +F +AFLF +ET+ +IGYG R +T++CP + + Q I G ++DAF++G Sbjct: 123 PPAPCFSHVASFLAAFLFALETQTSIGYGVRSVTEECPAAVAAVVLQCIAGCVLDAFVVG 182 Query: 179 CMFIKMSQPKKRAETLMFSEHAVISMRDGKLTLMFRVGNLRNSHMVSAQIRCKLLKSRQT 238 + KM++PKKR ETL+FSE+AV+++RD +L LM+RVGNLR SH+V A +R +LL+ R T Sbjct: 183 AVMAKMAKPKKRNETLVFSENAVVALRDHRLCLMWRVGNLRRSHLVEAHVRAQLLQPRVT 242 Query: 239 PEGEFLPLDQLELDVGFSTGADQLFLVSPLTICHVIDAKSPFYDLSQRSMQTEQFEIVVI 298 PEGE++PLD ++DVGF G D++FLVSP+TI H ID+ SP Y+L + + FE+VVI Sbjct: 243 PEGEYIPLDHQDVDVGFDGGTDRIFLVSPITIVHEIDSASPLYELGRAELARADFELVVI 302 Query: 299 LEGIVETTGMTCQARTSYTEDEVLWGHRFFPVISLEEGFFKVDYSQFHATFEVP-TPPYS 357 LEG+VE T MT Q R+SY E+LWGHRF PV+ ++VDY FH T+EVP TP S Sbjct: 303 LEGMVEATAMTTQCRSSYLPGELLWGHRFEPVLFQRGSQYEVDYRHFHRTYEVPGTPVCS 362 Query: 358 VKEQEE 363 KE +E Sbjct: 363 AKELDE 368 >gi|25777635 potassium inwardly-rectifying channel J14 [Homo sapiens] Length = 436 Score = 343 bits (880), Expect = 2e-94 Identities = 176/366 (48%), Positives = 242/366 (66%), Gaps = 8/366 (2%) Query: 3 ALRRKFG----DDYQVVTTSSSGSGLQPQGPGQDPQQQLVPKKKRQRFVDKNGRCNVQHG 58 ALRR G D + +G GL G P Q V ++ R RFV K+G CNV+ Sbjct: 6 ALRRLSGALDSGDSRAGDEEEAGPGLCRNGWAPAPVQSPVGRR-RGRFVKKDGHCNVRFV 64 Query: 59 NLGSETSRYLSDLFTTLVDLKWRWNLFIFILTYTVAWLFMASMWWVIAYTRGDLNKAHVG 118 NLG + +RYLSDLFTT VD++WRW +F ++ +WL +W+IA GDL A Sbjct: 65 NLGGQGARYLSDLFTTCVDVRWRWMCLLFSCSFLASWLLFGLAFWLIASLHGDL--AAPP 122 Query: 119 NYTPCVANVYNFPSAFLFFIETEATIGYGYRYITDKCPEGIILFLFQSILGSIVDAFLIG 178 PC ++V +F +AFLF +ET+ +IGYG R +T++CP + + Q I G ++DAF++G Sbjct: 123 PPAPCFSHVASFLAAFLFALETQTSIGYGVRSVTEECPAAVAAVVLQCIAGCVLDAFVVG 182 Query: 179 CMFIKMSQPKKRAETLMFSEHAVISMRDGKLTLMFRVGNLRNSHMVSAQIRCKLLKSRQT 238 + KM++PKKR ETL+FSE+AV+++RD +L LM+RVGNLR SH+V A +R +LL+ R T Sbjct: 183 AVMAKMAKPKKRNETLVFSENAVVALRDHRLCLMWRVGNLRRSHLVEAHVRAQLLQPRVT 242 Query: 239 PEGEFLPLDQLELDVGFSTGADQLFLVSPLTICHVIDAKSPFYDLSQRSMQTEQFEIVVI 298 PEGE++PLD ++DVGF G D++FLVSP+TI H ID+ SP Y+L + + FE+VVI Sbjct: 243 PEGEYIPLDHQDVDVGFDGGTDRIFLVSPITIVHEIDSASPLYELGRAELARADFELVVI 302 Query: 299 LEGIVETTGMTCQARTSYTEDEVLWGHRFFPVISLEEGFFKVDYSQFHATFEVP-TPPYS 357 LEG+VE T MT Q R+SY E+LWGHRF PV+ ++VDY FH T+EVP TP S Sbjct: 303 LEGMVEATAMTTQCRSSYLPGELLWGHRFEPVLFQRGSQYEVDYRHFHRTYEVPGTPVCS 362 Query: 358 VKEQEE 363 KE +E Sbjct: 363 AKELDE 368 >gi|62388888 potassium inwardly-rectifying channel J11 [Homo sapiens] Length = 390 Score = 330 bits (846), Expect = 2e-90 Identities = 156/325 (48%), Positives = 230/325 (70%), Gaps = 3/325 (0%) Query: 40 KKKRQRFVDKNGRCNVQHGNLGSETSRYLSDLFTTLVDLKWRWNLFIFILTYTVAWLFMA 99 +++R RFV K G CNV H N+ E R+L D+FTTLVDLKW L IF +++ +WL A Sbjct: 29 RQRRARFVSKKGNCNVAHKNI-REQGRFLQDVFTTLVDLKWPHTLLIFTMSFLCSWLLFA 87 Query: 100 SMWWVIAYTRGDLNKAHVGNYTPCVANVYNFPSAFLFFIETEATIGYGYRYITDKCPEGI 159 WW+IA+ GDL + G PCV ++++F SAFLF IE + TIG+G R +T++CP I Sbjct: 88 MAWWLIAFAHGDLAPSE-GTAEPCVTSIHSFSSAFLFSIEVQVTIGFGGRMVTEECPLAI 146 Query: 160 ILFLFQSILGSIVDAFLIGCMFIKMSQPKKRAETLMFSEHAVISMRDGKLTLMFRVGNLR 219 ++ + Q+I+G +++A ++GC+F+K +Q +RAETL+FS+HAVI++R G+L M RVG+LR Sbjct: 147 LILIVQNIVGLMINAIMLGCIFMKTAQAHRRAETLIFSKHAVIALRHGRLCFMLRVGDLR 206 Query: 220 NSHMVSAQIRCKLLKSRQTPEGEFLPLDQLELDVGFSTGADQLFLVSPLTICHVIDAKSP 279 S ++SA I ++++ +PEGE +PL Q+++ + G + +FLV+PL I HVIDA SP Sbjct: 207 KSMIISATIHMQVVRKTTSPEGEVVPLHQVDIPMENGVGGNSIFLVAPLIIYHVIDANSP 266 Query: 280 FYDLSQRSMQTEQ-FEIVVILEGIVETTGMTCQARTSYTEDEVLWGHRFFPVISLEEGFF 338 YDL+ + Q EI+VILEG+VETTG+T QARTSY DE+LWG RF P+++ E+G + Sbjct: 267 LYDLAPSDLHHHQDLEIIVILEGVVETTGITTQARTSYLADEILWGQRFVPIVAEEDGRY 326 Query: 339 KVDYSQFHATFEVPTPPYSVKEQEE 363 VDYS+F T +VPTP + ++ +E Sbjct: 327 SVDYSKFGNTVKVPTPLCTARQLDE 351 >gi|4826802 potassium inwardly-rectifying channel J8 [Homo sapiens] Length = 424 Score = 329 bits (844), Expect = 3e-90 Identities = 162/356 (45%), Positives = 241/356 (67%), Gaps = 14/356 (3%) Query: 43 RQRFVDKNGRCNVQHGNLGSETSRYLSDLFTTLVDLKWRWNLFIFILTYTVAWLFMASMW 102 + RF+ K+G CN+ H N+ E R+L D+FTTLVDLKWR L IF +++ +WL A MW Sbjct: 33 KARFIAKSGACNLAHKNI-REQGRFLQDIFTTLVDLKWRHTLVIFTMSFLCSWLLFAIMW 91 Query: 103 WVIAYTRGDL---------NKAHVGNYTPCVANVYNFPSAFLFFIETEATIGYGYRYITD 153 W++A+ GD+ K+ + + T CV NV +F SAFLF IE + TIG+G R +T+ Sbjct: 92 WLVAFAHGDIYAYMEKSGMEKSGLES-TVCVTNVRSFTSAFLFSIEVQVTIGFGGRMMTE 150 Query: 154 KCPEGIILFLFQSILGSIVDAFLIGCMFIKMSQPKKRAETLMFSEHAVISMRDGKLTLMF 213 +CP I + + Q+I+G I++A ++GC+F+K +Q +RAETL+FS HAVI++R+GKL MF Sbjct: 151 ECPLAITVLILQNIVGLIINAVMLGCIFMKTAQAHRRAETLIFSRHAVIAVRNGKLCFMF 210 Query: 214 RVGNLRNSHMVSAQIRCKLLKSRQTPEGEFLPLDQLELDVGFSTGADQLFLVSPLTICHV 273 RVG+LR S ++SA +R +++K TPEGE +P+ QL++ V ++ +FLV+PL ICHV Sbjct: 211 RVGDLRKSMIISASVRIQVVKKTTTPEGEVVPIHQLDIPVDNPIESNNIFLVAPLIICHV 270 Query: 274 IDAKSPFYDLSQRSMQTEQFEIVVILEGIVETTGMTCQARTSYTEDEVLWGHRFFPVISL 333 ID +SP YD+S + + E++VILEG+VETTG+T QARTSY +E+ WGHRF +++ Sbjct: 271 IDKRSPLYDISATDLANQDLEVIVILEGVVETTGITTQARTSYIAEEIQWGHRFVSIVTE 330 Query: 334 EEGFFKVDYSQFHATFEVPTPPYSVKEQEE---MLLMSSPLIAPAITNSKERHNSV 386 EEG + VDYS+F T +V P S +E +E +L+ + + NS + NS+ Sbjct: 331 EEGVYSVDYSKFGNTVKVAAPRCSARELDEKPSILIQTLQKSELSHQNSLRKRNSM 386 >gi|24497471 potassium inwardly-rectifying channel J1 isoform b [Homo sapiens] Length = 372 Score = 311 bits (798), Expect = 7e-85 Identities = 151/318 (47%), Positives = 221/318 (69%), Gaps = 5/318 (1%) Query: 41 KKRQRFVDKNGRCNVQHGNLGSETSRYLS--DLFTTLVDLKWRWNLFIFILTYTVAWLFM 98 ++R R V K+GRCN++ GN+ ++ SR++ D++TT++DLKWR+ + IFI + +W F Sbjct: 18 RQRARLVSKDGRCNIEFGNVEAQ-SRFIFFVDIWTTVLDLKWRYKMTIFITAFLGSWFFF 76 Query: 99 ASMWWVIAYTRGDLNKAHVG-NYTPCVANVYNFPSAFLFFIETEATIGYGYRYITDKCPE 157 +W+ +AY DL + H N+TPCV N+ SAFLF +ET+ TIGYG+R +T++C Sbjct: 77 GLLWYAVAYIHKDLPEFHPSANHTPCVENINGLTSAFLFSLETQVTIGYGFRCVTEQCAT 136 Query: 158 GIILFLFQSILGSIVDAFLIGCMFIKMSQPKKRAETLMFSEHAVISMRDGKLTLMFRVGN 217 I L +FQSILG I+++F+ G + K+S+PKKRA+T+ FS++AVIS R GKL L+ RV N Sbjct: 137 AIFLLIFQSILGVIINSFMCGAILAKISRPKKRAKTITFSKNAVISKRGGKLCLLIRVAN 196 Query: 218 LRNSHMVSAQIRCKLLKSRQTPEGEFLPLDQLELDVGFSTGADQLFLVSPLTICHVIDAK 277 LR S ++ + I KLLK+ TPEGE + LDQ+ ++ G + LF +SPLTI HVID Sbjct: 197 LRKSLLIGSHIYGKLLKTTVTPEGETIILDQININFVVDAGNENLFFISPLTIYHVIDHN 256 Query: 278 SPFYDLSQRSMQTEQFEIVVILEGIVETTGMTCQARTSYTEDEVLWGHRFFPVIS-LEEG 336 SPF+ ++ ++ + FE+VV L+G VE+T TCQ RTSY +EVLWG+RF P++S +EG Sbjct: 257 SPFFHMAAETLLQQDFELVVFLDGTVESTSATCQVRTSYVPEEVLWGYRFAPIVSKTKEG 316 Query: 337 FFKVDYSQFHATFEVPTP 354 ++VD+ F T EV TP Sbjct: 317 KYRVDFHNFSKTVEVETP 334 >gi|24497467 potassium inwardly-rectifying channel J1 isoform b [Homo sapiens] Length = 372 Score = 311 bits (798), Expect = 7e-85 Identities = 151/318 (47%), Positives = 221/318 (69%), Gaps = 5/318 (1%) Query: 41 KKRQRFVDKNGRCNVQHGNLGSETSRYLS--DLFTTLVDLKWRWNLFIFILTYTVAWLFM 98 ++R R V K+GRCN++ GN+ ++ SR++ D++TT++DLKWR+ + IFI + +W F Sbjct: 18 RQRARLVSKDGRCNIEFGNVEAQ-SRFIFFVDIWTTVLDLKWRYKMTIFITAFLGSWFFF 76 Query: 99 ASMWWVIAYTRGDLNKAHVG-NYTPCVANVYNFPSAFLFFIETEATIGYGYRYITDKCPE 157 +W+ +AY DL + H N+TPCV N+ SAFLF +ET+ TIGYG+R +T++C Sbjct: 77 GLLWYAVAYIHKDLPEFHPSANHTPCVENINGLTSAFLFSLETQVTIGYGFRCVTEQCAT 136 Query: 158 GIILFLFQSILGSIVDAFLIGCMFIKMSQPKKRAETLMFSEHAVISMRDGKLTLMFRVGN 217 I L +FQSILG I+++F+ G + K+S+PKKRA+T+ FS++AVIS R GKL L+ RV N Sbjct: 137 AIFLLIFQSILGVIINSFMCGAILAKISRPKKRAKTITFSKNAVISKRGGKLCLLIRVAN 196 Query: 218 LRNSHMVSAQIRCKLLKSRQTPEGEFLPLDQLELDVGFSTGADQLFLVSPLTICHVIDAK 277 LR S ++ + I KLLK+ TPEGE + LDQ+ ++ G + LF +SPLTI HVID Sbjct: 197 LRKSLLIGSHIYGKLLKTTVTPEGETIILDQININFVVDAGNENLFFISPLTIYHVIDHN 256 Query: 278 SPFYDLSQRSMQTEQFEIVVILEGIVETTGMTCQARTSYTEDEVLWGHRFFPVIS-LEEG 336 SPF+ ++ ++ + FE+VV L+G VE+T TCQ RTSY +EVLWG+RF P++S +EG Sbjct: 257 SPFFHMAAETLLQQDFELVVFLDGTVESTSATCQVRTSYVPEEVLWGYRFAPIVSKTKEG 316 Query: 337 FFKVDYSQFHATFEVPTP 354 ++VD+ F T EV TP Sbjct: 317 KYRVDFHNFSKTVEVETP 334 >gi|4504837 potassium inwardly-rectifying channel J1 isoform a [Homo sapiens] Length = 391 Score = 311 bits (798), Expect = 7e-85 Identities = 151/318 (47%), Positives = 221/318 (69%), Gaps = 5/318 (1%) Query: 41 KKRQRFVDKNGRCNVQHGNLGSETSRYLS--DLFTTLVDLKWRWNLFIFILTYTVAWLFM 98 ++R R V K+GRCN++ GN+ ++ SR++ D++TT++DLKWR+ + IFI + +W F Sbjct: 37 RQRARLVSKDGRCNIEFGNVEAQ-SRFIFFVDIWTTVLDLKWRYKMTIFITAFLGSWFFF 95 Query: 99 ASMWWVIAYTRGDLNKAHVG-NYTPCVANVYNFPSAFLFFIETEATIGYGYRYITDKCPE 157 +W+ +AY DL + H N+TPCV N+ SAFLF +ET+ TIGYG+R +T++C Sbjct: 96 GLLWYAVAYIHKDLPEFHPSANHTPCVENINGLTSAFLFSLETQVTIGYGFRCVTEQCAT 155 Query: 158 GIILFLFQSILGSIVDAFLIGCMFIKMSQPKKRAETLMFSEHAVISMRDGKLTLMFRVGN 217 I L +FQSILG I+++F+ G + K+S+PKKRA+T+ FS++AVIS R GKL L+ RV N Sbjct: 156 AIFLLIFQSILGVIINSFMCGAILAKISRPKKRAKTITFSKNAVISKRGGKLCLLIRVAN 215 Query: 218 LRNSHMVSAQIRCKLLKSRQTPEGEFLPLDQLELDVGFSTGADQLFLVSPLTICHVIDAK 277 LR S ++ + I KLLK+ TPEGE + LDQ+ ++ G + LF +SPLTI HVID Sbjct: 216 LRKSLLIGSHIYGKLLKTTVTPEGETIILDQININFVVDAGNENLFFISPLTIYHVIDHN 275 Query: 278 SPFYDLSQRSMQTEQFEIVVILEGIVETTGMTCQARTSYTEDEVLWGHRFFPVIS-LEEG 336 SPF+ ++ ++ + FE+VV L+G VE+T TCQ RTSY +EVLWG+RF P++S +EG Sbjct: 276 SPFFHMAAETLLQQDFELVVFLDGTVESTSATCQVRTSYVPEEVLWGYRFAPIVSKTKEG 335 Query: 337 FFKVDYSQFHATFEVPTP 354 ++VD+ F T EV TP Sbjct: 336 KYRVDFHNFSKTVEVETP 353 >gi|148539892 potassium inwardly-rectifying channel J1 isoform b [Homo sapiens] Length = 372 Score = 311 bits (798), Expect = 7e-85 Identities = 151/318 (47%), Positives = 221/318 (69%), Gaps = 5/318 (1%) Query: 41 KKRQRFVDKNGRCNVQHGNLGSETSRYLS--DLFTTLVDLKWRWNLFIFILTYTVAWLFM 98 ++R R V K+GRCN++ GN+ ++ SR++ D++TT++DLKWR+ + IFI + +W F Sbjct: 18 RQRARLVSKDGRCNIEFGNVEAQ-SRFIFFVDIWTTVLDLKWRYKMTIFITAFLGSWFFF 76 Query: 99 ASMWWVIAYTRGDLNKAHVG-NYTPCVANVYNFPSAFLFFIETEATIGYGYRYITDKCPE 157 +W+ +AY DL + H N+TPCV N+ SAFLF +ET+ TIGYG+R +T++C Sbjct: 77 GLLWYAVAYIHKDLPEFHPSANHTPCVENINGLTSAFLFSLETQVTIGYGFRCVTEQCAT 136 Query: 158 GIILFLFQSILGSIVDAFLIGCMFIKMSQPKKRAETLMFSEHAVISMRDGKLTLMFRVGN 217 I L +FQSILG I+++F+ G + K+S+PKKRA+T+ FS++AVIS R GKL L+ RV N Sbjct: 137 AIFLLIFQSILGVIINSFMCGAILAKISRPKKRAKTITFSKNAVISKRGGKLCLLIRVAN 196 Query: 218 LRNSHMVSAQIRCKLLKSRQTPEGEFLPLDQLELDVGFSTGADQLFLVSPLTICHVIDAK 277 LR S ++ + I KLLK+ TPEGE + LDQ+ ++ G + LF +SPLTI HVID Sbjct: 197 LRKSLLIGSHIYGKLLKTTVTPEGETIILDQININFVVDAGNENLFFISPLTIYHVIDHN 256 Query: 278 SPFYDLSQRSMQTEQFEIVVILEGIVETTGMTCQARTSYTEDEVLWGHRFFPVIS-LEEG 336 SPF+ ++ ++ + FE+VV L+G VE+T TCQ RTSY +EVLWG+RF P++S +EG Sbjct: 257 SPFFHMAAETLLQQDFELVVFLDGTVESTSATCQVRTSYVPEEVLWGYRFAPIVSKTKEG 316 Query: 337 FFKVDYSQFHATFEVPTP 354 ++VD+ F T EV TP Sbjct: 317 KYRVDFHNFSKTVEVETP 334 >gi|24497473 potassium inwardly-rectifying channel J1 isoform b [Homo sapiens] Length = 372 Score = 311 bits (798), Expect = 7e-85 Identities = 151/318 (47%), Positives = 221/318 (69%), Gaps = 5/318 (1%) Query: 41 KKRQRFVDKNGRCNVQHGNLGSETSRYLS--DLFTTLVDLKWRWNLFIFILTYTVAWLFM 98 ++R R V K+GRCN++ GN+ ++ SR++ D++TT++DLKWR+ + IFI + +W F Sbjct: 18 RQRARLVSKDGRCNIEFGNVEAQ-SRFIFFVDIWTTVLDLKWRYKMTIFITAFLGSWFFF 76 Query: 99 ASMWWVIAYTRGDLNKAHVG-NYTPCVANVYNFPSAFLFFIETEATIGYGYRYITDKCPE 157 +W+ +AY DL + H N+TPCV N+ SAFLF +ET+ TIGYG+R +T++C Sbjct: 77 GLLWYAVAYIHKDLPEFHPSANHTPCVENINGLTSAFLFSLETQVTIGYGFRCVTEQCAT 136 Query: 158 GIILFLFQSILGSIVDAFLIGCMFIKMSQPKKRAETLMFSEHAVISMRDGKLTLMFRVGN 217 I L +FQSILG I+++F+ G + K+S+PKKRA+T+ FS++AVIS R GKL L+ RV N Sbjct: 137 AIFLLIFQSILGVIINSFMCGAILAKISRPKKRAKTITFSKNAVISKRGGKLCLLIRVAN 196 Query: 218 LRNSHMVSAQIRCKLLKSRQTPEGEFLPLDQLELDVGFSTGADQLFLVSPLTICHVIDAK 277 LR S ++ + I KLLK+ TPEGE + LDQ+ ++ G + LF +SPLTI HVID Sbjct: 197 LRKSLLIGSHIYGKLLKTTVTPEGETIILDQININFVVDAGNENLFFISPLTIYHVIDHN 256 Query: 278 SPFYDLSQRSMQTEQFEIVVILEGIVETTGMTCQARTSYTEDEVLWGHRFFPVIS-LEEG 336 SPF+ ++ ++ + FE+VV L+G VE+T TCQ RTSY +EVLWG+RF P++S +EG Sbjct: 257 SPFFHMAAETLLQQDFELVVFLDGTVESTSATCQVRTSYVPEEVLWGYRFAPIVSKTKEG 316 Query: 337 FFKVDYSQFHATFEVPTP 354 ++VD+ F T EV TP Sbjct: 317 KYRVDFHNFSKTVEVETP 334 >gi|25121966 potassium inwardly-rectifying channel, subfamily J, member 10 [Homo sapiens] Length = 379 Score = 273 bits (697), Expect = 3e-73 Identities = 134/318 (42%), Positives = 203/318 (63%), Gaps = 3/318 (0%) Query: 39 PKKKRQRFVDKNGRCNVQHGNLGSETSRYLSDLFTTLVDLKWRWNLFIFILTYTVAWLFM 98 P +R+R + K+GR NV+ ++ + YL DL+TT +D++WR+ L +F T+ W Sbjct: 23 PGIRRRRVLTKDGRSNVRMEHIADKRFLYLKDLWTTFIDMQWRYKLLLFSATFAGTWFLF 82 Query: 99 ASMWWVIAYTRGDLNKAHV-GNYTPCVANVYNFPSAFLFFIETEATIGYGYRYITDKCPE 157 +W+++A GDL + N+TPCV V+ AFLF +E++ TIGYG+RYI+++CP Sbjct: 83 GVVWYLVAVAHGDLLELDPPANHTPCVVQVHTLTGAFLFSLESQTTIGYGFRYISEECPL 142 Query: 158 GIILFLFQSILGSIVDAFLIGCMFIKMSQPKKRAETLMFSEHAVISMRDGKLTLMFRVGN 217 I+L + Q +L +I++ F+ G K+++PKKRAET+ FS+HAV++ +GK LM RV N Sbjct: 143 AIVLLIAQLVLTTILEIFITGTFLAKIARPKKRAETIRFSQHAVVASHNGKPCLMIRVAN 202 Query: 218 LRNSHMVSAQIRCKLLKSRQTPEGEFLPLDQLELDVGFSTGADQLFLVSPLTICHVIDAK 277 +R S ++ Q+ KLL++ QT EGE + L+Q+ + T +D FL+ PLT HV+D Sbjct: 203 MRKSLLIGCQVTGKLLQTHQTKEGENIRLNQVNVTFQVDTASDSPFLILPLTFYHVVDET 262 Query: 278 SPFYDLSQRSMQTEQFEIVVILEGIVETTGMTCQARTSYTEDEVLWGHRFFPVISLE-EG 336 SP DL RS + + FE+V+IL G VE+T TCQ RTSY +E+LWG+ F P ISL G Sbjct: 263 SPLKDLPLRSGEGD-FELVLILSGTVESTSATCQVRTSYLPEEILWGYEFTPAISLSASG 321 Query: 337 FFKVDYSQFHATFEVPTP 354 + D+S F +V +P Sbjct: 322 KYIADFSLFDQVVKVASP 339 >gi|8923823 potassium inwardly-rectifying channel J16 [Homo sapiens] Length = 418 Score = 268 bits (686), Expect = 7e-72 Identities = 144/385 (37%), Positives = 230/385 (59%), Gaps = 22/385 (5%) Query: 8 FGDDYQVVTTSSSGSGLQPQGPGQDPQQQLVPKKK-RQRFVDKNGRCNVQHGNLGSETSR 66 +G Y ++ + + PG P+ + K++ R+R + K+G CNV ++ E Sbjct: 4 YGSSYHIINADA-------KYPGYPPEHIIAEKRRARRRLLHKDGSCNVYFKHIFGEWGS 56 Query: 67 YLSDLFTTLVDLKWRWNLFIFILTYTVAWLFMASMWWVIAYTRGDLNKAHVGNYTPCVAN 126 Y+ D+FTTLVD KWR IF L+Y ++WL S++W+IA+ GDL + + TPCV N Sbjct: 57 YVVDIFTTLVDTKWRHMFVIFSLSYILSWLIFGSVFWLIAFHHGDL--LNDPDITPCVDN 114 Query: 127 VYNFPSAFLFFIETEATIGYGYRYITDKCPEGIILFLFQSILGSIVDAFLIGCMFIKMSQ 186 V++F AFLF +ET+ TIGYGYR +T++C +++ + QSIL I++ F+IG KM+ Sbjct: 115 VHSFTGAFLFSLETQTTIGYGYRCVTEECSVAVLMVILQSILSCIINTFIIGAALAKMAT 174 Query: 187 PKKRAETLMFSEHAVISMRDGKLTLMFRVGNLRNSHMVSAQIRCKLLKSRQTPEGEF-LP 245 +KRA+T+ FS A+I MRDGKL LM+R+G+ R +H+V +R +LL+ + EG + Sbjct: 175 ARKRAQTIRFSYFALIGMRDGKLCLMWRIGDFRPNHVVEGTVRAQLLRYTEDSEGRMTMA 234 Query: 246 LDQLELDVGFSTGADQLFLVSPLTICHVIDAKSPFYDLSQRSMQTEQFEIVVILEGIVET 305 L+L DQ+ LV+P+TI H ID +SP Y L ++++ + FEI+V ++ Sbjct: 235 FKDLKL------VNDQIILVTPVTIVHEIDHESPLYALDRKAVAKDNFEILVTFIYTGDS 288 Query: 306 TGMTCQARTSYTEDEVLWGHRFFPVISLEEGFFKVDYSQFHATFEVPTPPYSV-----KE 360 TG + Q+R+SY E+LWGHRF V+ ++ ++KV+ QF + EV P S K+ Sbjct: 289 TGTSHQSRSSYVPREILWGHRFNDVLEVKRKYYKVNCLQFEGSVEVYAPFCSAKQLDWKD 348 Query: 361 QEEMLLMSSPLIAPAITNSKERHNS 385 Q+ + + P+ +++K R S Sbjct: 349 QQLHIEKAPPVRESCTSDTKARRRS 373 >gi|25777630 potassium inwardly-rectifying channel J16 [Homo sapiens] Length = 418 Score = 268 bits (686), Expect = 7e-72 Identities = 144/385 (37%), Positives = 230/385 (59%), Gaps = 22/385 (5%) Query: 8 FGDDYQVVTTSSSGSGLQPQGPGQDPQQQLVPKKK-RQRFVDKNGRCNVQHGNLGSETSR 66 +G Y ++ + + PG P+ + K++ R+R + K+G CNV ++ E Sbjct: 4 YGSSYHIINADA-------KYPGYPPEHIIAEKRRARRRLLHKDGSCNVYFKHIFGEWGS 56 Query: 67 YLSDLFTTLVDLKWRWNLFIFILTYTVAWLFMASMWWVIAYTRGDLNKAHVGNYTPCVAN 126 Y+ D+FTTLVD KWR IF L+Y ++WL S++W+IA+ GDL + + TPCV N Sbjct: 57 YVVDIFTTLVDTKWRHMFVIFSLSYILSWLIFGSVFWLIAFHHGDL--LNDPDITPCVDN 114 Query: 127 VYNFPSAFLFFIETEATIGYGYRYITDKCPEGIILFLFQSILGSIVDAFLIGCMFIKMSQ 186 V++F AFLF +ET+ TIGYGYR +T++C +++ + QSIL I++ F+IG KM+ Sbjct: 115 VHSFTGAFLFSLETQTTIGYGYRCVTEECSVAVLMVILQSILSCIINTFIIGAALAKMAT 174 Query: 187 PKKRAETLMFSEHAVISMRDGKLTLMFRVGNLRNSHMVSAQIRCKLLKSRQTPEGEF-LP 245 +KRA+T+ FS A+I MRDGKL LM+R+G+ R +H+V +R +LL+ + EG + Sbjct: 175 ARKRAQTIRFSYFALIGMRDGKLCLMWRIGDFRPNHVVEGTVRAQLLRYTEDSEGRMTMA 234 Query: 246 LDQLELDVGFSTGADQLFLVSPLTICHVIDAKSPFYDLSQRSMQTEQFEIVVILEGIVET 305 L+L DQ+ LV+P+TI H ID +SP Y L ++++ + FEI+V ++ Sbjct: 235 FKDLKL------VNDQIILVTPVTIVHEIDHESPLYALDRKAVAKDNFEILVTFIYTGDS 288 Query: 306 TGMTCQARTSYTEDEVLWGHRFFPVISLEEGFFKVDYSQFHATFEVPTPPYSV-----KE 360 TG + Q+R+SY E+LWGHRF V+ ++ ++KV+ QF + EV P S K+ Sbjct: 289 TGTSHQSRSSYVPREILWGHRFNDVLEVKRKYYKVNCLQFEGSVEVYAPFCSAKQLDWKD 348 Query: 361 QEEMLLMSSPLIAPAITNSKERHNS 385 Q+ + + P+ +++K R S Sbjct: 349 QQLHIEKAPPVRESCTSDTKARRRS 373 >gi|25777628 potassium inwardly-rectifying channel J16 [Homo sapiens] Length = 418 Score = 268 bits (686), Expect = 7e-72 Identities = 144/385 (37%), Positives = 230/385 (59%), Gaps = 22/385 (5%) Query: 8 FGDDYQVVTTSSSGSGLQPQGPGQDPQQQLVPKKK-RQRFVDKNGRCNVQHGNLGSETSR 66 +G Y ++ + + PG P+ + K++ R+R + K+G CNV ++ E Sbjct: 4 YGSSYHIINADA-------KYPGYPPEHIIAEKRRARRRLLHKDGSCNVYFKHIFGEWGS 56 Query: 67 YLSDLFTTLVDLKWRWNLFIFILTYTVAWLFMASMWWVIAYTRGDLNKAHVGNYTPCVAN 126 Y+ D+FTTLVD KWR IF L+Y ++WL S++W+IA+ GDL + + TPCV N Sbjct: 57 YVVDIFTTLVDTKWRHMFVIFSLSYILSWLIFGSVFWLIAFHHGDL--LNDPDITPCVDN 114 Query: 127 VYNFPSAFLFFIETEATIGYGYRYITDKCPEGIILFLFQSILGSIVDAFLIGCMFIKMSQ 186 V++F AFLF +ET+ TIGYGYR +T++C +++ + QSIL I++ F+IG KM+ Sbjct: 115 VHSFTGAFLFSLETQTTIGYGYRCVTEECSVAVLMVILQSILSCIINTFIIGAALAKMAT 174 Query: 187 PKKRAETLMFSEHAVISMRDGKLTLMFRVGNLRNSHMVSAQIRCKLLKSRQTPEGEF-LP 245 +KRA+T+ FS A+I MRDGKL LM+R+G+ R +H+V +R +LL+ + EG + Sbjct: 175 ARKRAQTIRFSYFALIGMRDGKLCLMWRIGDFRPNHVVEGTVRAQLLRYTEDSEGRMTMA 234 Query: 246 LDQLELDVGFSTGADQLFLVSPLTICHVIDAKSPFYDLSQRSMQTEQFEIVVILEGIVET 305 L+L DQ+ LV+P+TI H ID +SP Y L ++++ + FEI+V ++ Sbjct: 235 FKDLKL------VNDQIILVTPVTIVHEIDHESPLYALDRKAVAKDNFEILVTFIYTGDS 288 Query: 306 TGMTCQARTSYTEDEVLWGHRFFPVISLEEGFFKVDYSQFHATFEVPTPPYSV-----KE 360 TG + Q+R+SY E+LWGHRF V+ ++ ++KV+ QF + EV P S K+ Sbjct: 289 TGTSHQSRSSYVPREILWGHRFNDVLEVKRKYYKVNCLQFEGSVEVYAPFCSAKQLDWKD 348 Query: 361 QEEMLLMSSPLIAPAITNSKERHNS 385 Q+ + + P+ +++K R S Sbjct: 349 QQLHIEKAPPVRESCTSDTKARRRS 373 >gi|21361127 potassium inwardly-rectifying channel J15 [Homo sapiens] Length = 375 Score = 253 bits (646), Expect = 3e-67 Identities = 123/329 (37%), Positives = 201/329 (61%), Gaps = 2/329 (0%) Query: 40 KKKRQRFVDKNGRCNVQHGNLGSETSRYLSDLFTTLVDLKWRWNLFIFILTYTVAWLFMA 99 K R R + K+G NV+ + YL DL+TT++D+KWR+ L +F T+ + W Sbjct: 23 KANRPRVMSKSGHSNVRIDKVDGIYLLYLQDLWTTVIDMKWRYKLTLFAATFVMTWFLFG 82 Query: 100 SMWWVIAYTRGDLNKAH-VGNYTPCVANVYNFPSAFLFFIETEATIGYGYRYITDKCPEG 158 +++ IA+ GDL + N+TPC+ V + AFLF +E++ TIGYG R IT++CP Sbjct: 83 VIYYAIAFIHGDLEPGEPISNHTPCIMKVDSLTGAFLFSLESQTTIGYGVRSITEECPHA 142 Query: 159 IILFLFQSILGSIVDAFLIGCMFIKMSQPKKRAETLMFSEHAVISMRDGKLTLMFRVGNL 218 I L + Q ++ ++++ F+ G K+++PKKRAET+ FS AVI+ ++GKL L+ +V N+ Sbjct: 143 IFLLVAQLVITTLIEIFITGTFLAKIARPKKRAETIKFSHCAVITKQNGKLCLVIQVANM 202 Query: 219 RNSHMVSAQIRCKLLKSRQTPEGEFLPLDQLELDVGFSTGADQLFLVSPLTICHVIDAKS 278 R S ++ Q+ KLL++ T EGE + L+Q + + ++ FL+ P+T HV+D S Sbjct: 203 RKSLLIQCQLSGKLLQTHVTKEGERILLNQATVKFHVDSSSESPFLILPMTFYHVLDETS 262 Query: 279 PFYDLSQRSMQTEQFEIVVILEGIVETTGMTCQARTSYTEDEVLWGHRFFPVISL-EEGF 337 P DL+ ++++ ++FE+VV+L VE+T CQ+RTSY +E+ WG F PV+SL + G Sbjct: 263 PLRDLTPQNLKEKEFELVVLLNATVESTSAVCQSRTSYIPEEIYWGFEFVPVVSLSKNGK 322 Query: 338 FKVDYSQFHATFEVPTPPYSVKEQEEMLL 366 + D+SQF + P + + E+ L Sbjct: 323 YVADFSQFEQIRKSPDCTFYCADSEKQQL 351 >gi|25777640 potassium inwardly-rectifying channel J15 [Homo sapiens] Length = 375 Score = 253 bits (646), Expect = 3e-67 Identities = 123/329 (37%), Positives = 201/329 (61%), Gaps = 2/329 (0%) Query: 40 KKKRQRFVDKNGRCNVQHGNLGSETSRYLSDLFTTLVDLKWRWNLFIFILTYTVAWLFMA 99 K R R + K+G NV+ + YL DL+TT++D+KWR+ L +F T+ + W Sbjct: 23 KANRPRVMSKSGHSNVRIDKVDGIYLLYLQDLWTTVIDMKWRYKLTLFAATFVMTWFLFG 82 Query: 100 SMWWVIAYTRGDLNKAH-VGNYTPCVANVYNFPSAFLFFIETEATIGYGYRYITDKCPEG 158 +++ IA+ GDL + N+TPC+ V + AFLF +E++ TIGYG R IT++CP Sbjct: 83 VIYYAIAFIHGDLEPGEPISNHTPCIMKVDSLTGAFLFSLESQTTIGYGVRSITEECPHA 142 Query: 159 IILFLFQSILGSIVDAFLIGCMFIKMSQPKKRAETLMFSEHAVISMRDGKLTLMFRVGNL 218 I L + Q ++ ++++ F+ G K+++PKKRAET+ FS AVI+ ++GKL L+ +V N+ Sbjct: 143 IFLLVAQLVITTLIEIFITGTFLAKIARPKKRAETIKFSHCAVITKQNGKLCLVIQVANM 202 Query: 219 RNSHMVSAQIRCKLLKSRQTPEGEFLPLDQLELDVGFSTGADQLFLVSPLTICHVIDAKS 278 R S ++ Q+ KLL++ T EGE + L+Q + + ++ FL+ P+T HV+D S Sbjct: 203 RKSLLIQCQLSGKLLQTHVTKEGERILLNQATVKFHVDSSSESPFLILPMTFYHVLDETS 262 Query: 279 PFYDLSQRSMQTEQFEIVVILEGIVETTGMTCQARTSYTEDEVLWGHRFFPVISL-EEGF 337 P DL+ ++++ ++FE+VV+L VE+T CQ+RTSY +E+ WG F PV+SL + G Sbjct: 263 PLRDLTPQNLKEKEFELVVLLNATVESTSAVCQSRTSYIPEEIYWGFEFVPVVSLSKNGK 322 Query: 338 FKVDYSQFHATFEVPTPPYSVKEQEEMLL 366 + D+SQF + P + + E+ L Sbjct: 323 YVADFSQFEQIRKSPDCTFYCADSEKQQL 351 >gi|25777638 potassium inwardly-rectifying channel J15 [Homo sapiens] Length = 375 Score = 253 bits (646), Expect = 3e-67 Identities = 123/329 (37%), Positives = 201/329 (61%), Gaps = 2/329 (0%) Query: 40 KKKRQRFVDKNGRCNVQHGNLGSETSRYLSDLFTTLVDLKWRWNLFIFILTYTVAWLFMA 99 K R R + K+G NV+ + YL DL+TT++D+KWR+ L +F T+ + W Sbjct: 23 KANRPRVMSKSGHSNVRIDKVDGIYLLYLQDLWTTVIDMKWRYKLTLFAATFVMTWFLFG 82 Query: 100 SMWWVIAYTRGDLNKAH-VGNYTPCVANVYNFPSAFLFFIETEATIGYGYRYITDKCPEG 158 +++ IA+ GDL + N+TPC+ V + AFLF +E++ TIGYG R IT++CP Sbjct: 83 VIYYAIAFIHGDLEPGEPISNHTPCIMKVDSLTGAFLFSLESQTTIGYGVRSITEECPHA 142 Query: 159 IILFLFQSILGSIVDAFLIGCMFIKMSQPKKRAETLMFSEHAVISMRDGKLTLMFRVGNL 218 I L + Q ++ ++++ F+ G K+++PKKRAET+ FS AVI+ ++GKL L+ +V N+ Sbjct: 143 IFLLVAQLVITTLIEIFITGTFLAKIARPKKRAETIKFSHCAVITKQNGKLCLVIQVANM 202 Query: 219 RNSHMVSAQIRCKLLKSRQTPEGEFLPLDQLELDVGFSTGADQLFLVSPLTICHVIDAKS 278 R S ++ Q+ KLL++ T EGE + L+Q + + ++ FL+ P+T HV+D S Sbjct: 203 RKSLLIQCQLSGKLLQTHVTKEGERILLNQATVKFHVDSSSESPFLILPMTFYHVLDETS 262 Query: 279 PFYDLSQRSMQTEQFEIVVILEGIVETTGMTCQARTSYTEDEVLWGHRFFPVISL-EEGF 337 P DL+ ++++ ++FE+VV+L VE+T CQ+RTSY +E+ WG F PV+SL + G Sbjct: 263 PLRDLTPQNLKEKEFELVVLLNATVESTSAVCQSRTSYIPEEIYWGFEFVPVVSLSKNGK 322 Query: 338 FKVDYSQFHATFEVPTPPYSVKEQEEMLL 366 + D+SQF + P + + E+ L Sbjct: 323 YVADFSQFEQIRKSPDCTFYCADSEKQQL 351 >gi|156119627 potassium inwardly-rectifying channel J13 [Homo sapiens] Length = 360 Score = 179 bits (453), Expect = 7e-45 Identities = 105/319 (32%), Positives = 168/319 (52%), Gaps = 10/319 (3%) Query: 41 KKRQRFVDKNGRCNVQHGNLGSETSRYLSDLFTTLVDLKWRWNLFIFILTYTVAWLFMAS 100 ++ +R V K+G +Q YL D + L+D++WRW + +F ++ V WL A Sbjct: 15 QRYRRMVTKDGHSTLQMDG-AQRGLAYLRDAWGILMDMRWRWMMLVFSASFVVHWLVFAV 73 Query: 101 MWWVIAYTRGDLNKAHVG---NYTPCVANVYNFPSAFLFFIETEATIGYGYRYITDKCPE 157 +W+V+A GDL H N+T CV + +F +AF F +ET+ TIGYG + + CP Sbjct: 74 LWYVLAEMNGDLELDHDAPPENHTICVKYITSFTAAFSFSLETQLTIGYGTMFPSGDCPS 133 Query: 158 GIILFLFQSILGSIVDAFLIGCMFIKMSQPKKRAETLMFSEHAVISMRDGKLTLMFRVGN 217 I L Q +LG +++AF+ G K+++PK RA ++ F++ AV++ DGK L+F+V N Sbjct: 134 AIALLAIQMLLGLMLEAFITGAFVAKIARPKNRAFSIRFTDTAVVAHMDGKPNLIFQVAN 193 Query: 218 LRNSHMVSAQIRCKLLKSRQTPEGEFLPLDQLELDVGFSTGADQLFLVSPLTICHVIDAK 277 R S + S ++ L + R+ + L ++ + + + F + PLT H I Sbjct: 194 TRPSPLTSVRVSAVLYQERENGK---LYQTSVDFHLDGISSDECPFFIFPLTYYHSITPS 250 Query: 278 SPFYDLSQRSMQTEQFEIVVILEGIVETTGMTCQARTSYTEDEVLWGHRFFPVISL-EEG 336 SP L Q FE+VV L + E TG CQ RTSY E++ H F +++ +G Sbjct: 251 SPLATLLQHE-NPSHFELVVFLSAMQEGTGEICQRRTSYLPSEIMLHHCFASLLTRGSKG 309 Query: 337 FFKVDYSQFHATF-EVPTP 354 +++ F T E PTP Sbjct: 310 EYQIKMENFDKTVPEFPTP 328 >gi|148806865 zinc finger protein 492 [Homo sapiens] Length = 531 Score = 33.5 bits (75), Expect = 0.46 Identities = 35/175 (20%), Positives = 63/175 (36%), Gaps = 9/175 (5%) Query: 311 QARTSYTEDEVLWGHRFFPVISLEEGFFKVDYSQFHATFEVPTPPYSVKEQEEMLLMSSP 370 Q+ T T + G +F+ + F + + H PY +E + +SS Sbjct: 348 QSSTLTTHKRIHAGEKFYKCEVCSKAFSRFSHLTTHKRIHTGEKPYKCEECGKAFNLSSQ 407 Query: 371 LIAPAITNSKER-HNSVECLDGLDDITTKLPSKL----QKITGREDFPKKLLRMSSTTSE 425 L I ++ E+ + EC + +T K+ +K E+ K + S T+ Sbjct: 408 LTTHKIIHTGEKPYKCEECGKAFNQSSTLSKHKVIHTGEKPYKYEECGKAFNQSSHLTTH 467 Query: 426 KAYSLGDLPMKLQRISSVPGNS----EEKLVSKTTKMLSDPMSQSVADLPPKLQK 476 K G+ P K + NS K++ K+ + D K+ K Sbjct: 468 KMIHTGEKPYKCEECGKAFNNSSILNRHKMIHTGEKLYKPESCNNACDNIAKISK 522 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.320 0.135 0.400 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 18,582,333 Number of Sequences: 37866 Number of extensions: 810029 Number of successful extensions: 2231 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 39 Number of HSP's successfully gapped in prelim test: 15 Number of HSP's that attempted gapping in prelim test: 2133 Number of HSP's gapped (non-prelim): 68 length of query: 501 length of database: 18,247,518 effective HSP length: 106 effective length of query: 395 effective length of database: 14,233,722 effective search space: 5622320190 effective search space used: 5622320190 T: 11 A: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.