Guide to the Human Genome
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Search of human proteins with 4504839

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|4504839 potassium inwardly-rectifying channel J3 [Homo
sapiens]
         (501 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|4504839 potassium inwardly-rectifying channel J3 [Homo sapiens]   1006   0.0  
gi|4504843 potassium inwardly-rectifying channel J6 [Homo sapiens]    452   e-127
gi|24797141 potassium inwardly-rectifying channel J5 [Homo sapiens]   450   e-126
gi|25121970 potassium inwardly-rectifying channel subfamily J9 [...   440   e-123
gi|4504835 potassium inwardly-rectifying channel J2 [Homo sapiens]    379   e-105
gi|23110982 potassium inwardly-rectifying channel, subfamily J, ...   372   e-103
gi|239758082 PREDICTED: similar to thyrotoxic periodic paralysis...   366   e-101
gi|4826798 potassium inwardly-rectifying channel J4 [Homo sapiens]    358   8e-99
gi|23110984 potassium inwardly-rectifying channel J4 [Homo sapiens]   358   8e-99
gi|239757993 PREDICTED: similar to inward rectifying K+ channel ...   354   9e-98
gi|239757991 PREDICTED: similar to inward rectifying K+ channel ...   354   9e-98
gi|239751249 PREDICTED: hypothetical protein XP_002347768 [Homo ...   354   9e-98
gi|7019439 potassium inwardly-rectifying channel J14 [Homo sapiens]   343   2e-94
gi|25777635 potassium inwardly-rectifying channel J14 [Homo sapi...   343   2e-94
gi|62388888 potassium inwardly-rectifying channel J11 [Homo sapi...   330   2e-90
gi|4826802 potassium inwardly-rectifying channel J8 [Homo sapiens]    329   3e-90
gi|24497471 potassium inwardly-rectifying channel J1 isoform b [...   311   7e-85
gi|24497467 potassium inwardly-rectifying channel J1 isoform b [...   311   7e-85
gi|4504837 potassium inwardly-rectifying channel J1 isoform a [H...   311   7e-85
gi|148539892 potassium inwardly-rectifying channel J1 isoform b ...   311   7e-85
gi|24497473 potassium inwardly-rectifying channel J1 isoform b [...   311   7e-85
gi|25121966 potassium inwardly-rectifying channel, subfamily J, ...   273   3e-73
gi|8923823 potassium inwardly-rectifying channel J16 [Homo sapiens]   268   7e-72
gi|25777630 potassium inwardly-rectifying channel J16 [Homo sapi...   268   7e-72
gi|25777628 potassium inwardly-rectifying channel J16 [Homo sapi...   268   7e-72
gi|21361127 potassium inwardly-rectifying channel J15 [Homo sapi...   253   3e-67
gi|25777640 potassium inwardly-rectifying channel J15 [Homo sapi...   253   3e-67
gi|25777638 potassium inwardly-rectifying channel J15 [Homo sapi...   253   3e-67
gi|156119627 potassium inwardly-rectifying channel J13 [Homo sap...   179   7e-45
gi|148806865 zinc finger protein 492 [Homo sapiens]                    33   0.46 

>gi|4504839 potassium inwardly-rectifying channel J3 [Homo sapiens]
          Length = 501

 Score = 1006 bits (2602), Expect = 0.0
 Identities = 501/501 (100%), Positives = 501/501 (100%)

Query: 1   MSALRRKFGDDYQVVTTSSSGSGLQPQGPGQDPQQQLVPKKKRQRFVDKNGRCNVQHGNL 60
           MSALRRKFGDDYQVVTTSSSGSGLQPQGPGQDPQQQLVPKKKRQRFVDKNGRCNVQHGNL
Sbjct: 1   MSALRRKFGDDYQVVTTSSSGSGLQPQGPGQDPQQQLVPKKKRQRFVDKNGRCNVQHGNL 60

Query: 61  GSETSRYLSDLFTTLVDLKWRWNLFIFILTYTVAWLFMASMWWVIAYTRGDLNKAHVGNY 120
           GSETSRYLSDLFTTLVDLKWRWNLFIFILTYTVAWLFMASMWWVIAYTRGDLNKAHVGNY
Sbjct: 61  GSETSRYLSDLFTTLVDLKWRWNLFIFILTYTVAWLFMASMWWVIAYTRGDLNKAHVGNY 120

Query: 121 TPCVANVYNFPSAFLFFIETEATIGYGYRYITDKCPEGIILFLFQSILGSIVDAFLIGCM 180
           TPCVANVYNFPSAFLFFIETEATIGYGYRYITDKCPEGIILFLFQSILGSIVDAFLIGCM
Sbjct: 121 TPCVANVYNFPSAFLFFIETEATIGYGYRYITDKCPEGIILFLFQSILGSIVDAFLIGCM 180

Query: 181 FIKMSQPKKRAETLMFSEHAVISMRDGKLTLMFRVGNLRNSHMVSAQIRCKLLKSRQTPE 240
           FIKMSQPKKRAETLMFSEHAVISMRDGKLTLMFRVGNLRNSHMVSAQIRCKLLKSRQTPE
Sbjct: 181 FIKMSQPKKRAETLMFSEHAVISMRDGKLTLMFRVGNLRNSHMVSAQIRCKLLKSRQTPE 240

Query: 241 GEFLPLDQLELDVGFSTGADQLFLVSPLTICHVIDAKSPFYDLSQRSMQTEQFEIVVILE 300
           GEFLPLDQLELDVGFSTGADQLFLVSPLTICHVIDAKSPFYDLSQRSMQTEQFEIVVILE
Sbjct: 241 GEFLPLDQLELDVGFSTGADQLFLVSPLTICHVIDAKSPFYDLSQRSMQTEQFEIVVILE 300

Query: 301 GIVETTGMTCQARTSYTEDEVLWGHRFFPVISLEEGFFKVDYSQFHATFEVPTPPYSVKE 360
           GIVETTGMTCQARTSYTEDEVLWGHRFFPVISLEEGFFKVDYSQFHATFEVPTPPYSVKE
Sbjct: 301 GIVETTGMTCQARTSYTEDEVLWGHRFFPVISLEEGFFKVDYSQFHATFEVPTPPYSVKE 360

Query: 361 QEEMLLMSSPLIAPAITNSKERHNSVECLDGLDDITTKLPSKLQKITGREDFPKKLLRMS 420
           QEEMLLMSSPLIAPAITNSKERHNSVECLDGLDDITTKLPSKLQKITGREDFPKKLLRMS
Sbjct: 361 QEEMLLMSSPLIAPAITNSKERHNSVECLDGLDDITTKLPSKLQKITGREDFPKKLLRMS 420

Query: 421 STTSEKAYSLGDLPMKLQRISSVPGNSEEKLVSKTTKMLSDPMSQSVADLPPKLQKMAGG 480
           STTSEKAYSLGDLPMKLQRISSVPGNSEEKLVSKTTKMLSDPMSQSVADLPPKLQKMAGG
Sbjct: 421 STTSEKAYSLGDLPMKLQRISSVPGNSEEKLVSKTTKMLSDPMSQSVADLPPKLQKMAGG 480

Query: 481 AARMEGNLPAKLRKMNSDRFT 501
           AARMEGNLPAKLRKMNSDRFT
Sbjct: 481 AARMEGNLPAKLRKMNSDRFT 501


>gi|4504843 potassium inwardly-rectifying channel J6 [Homo sapiens]
          Length = 423

 Score =  452 bits (1162), Expect = e-127
 Identities = 213/348 (61%), Positives = 277/348 (79%), Gaps = 1/348 (0%)

Query: 40  KKKRQRFVDKNGRCNVQHGNLGSETSRYLSDLFTTLVDLKWRWNLFIFILTYTVAWLFMA 99
           K+K QR+V K+G+CNV HGN+  ET RYL+D+FTTLVDLKWR+NL IF++ YTV WLF  
Sbjct: 50  KRKIQRYVRKDGKCNVHHGNV-RETYRYLTDIFTTLVDLKWRFNLLIFVMVYTVTWLFFG 108

Query: 100 SMWWVIAYTRGDLNKAHVGNYTPCVANVYNFPSAFLFFIETEATIGYGYRYITDKCPEGI 159
            +WW+IAY RGD++     ++TPCV N+  F SAFLF IETE TIGYGYR ITDKCPEGI
Sbjct: 109 MIWWLIAYIRGDMDHIEDPSWTPCVTNLNGFVSAFLFSIETETTIGYGYRVITDKCPEGI 168

Query: 160 ILFLFQSILGSIVDAFLIGCMFIKMSQPKKRAETLMFSEHAVISMRDGKLTLMFRVGNLR 219
           IL L QS+LGSIV+AF++GCMF+K+SQPKKRAETL+FS HAVISMRDGKL LMFRVG+LR
Sbjct: 169 ILLLIQSVLGSIVNAFMVGCMFVKISQPKKRAETLVFSTHAVISMRDGKLCLMFRVGDLR 228

Query: 220 NSHMVSAQIRCKLLKSRQTPEGEFLPLDQLELDVGFSTGADQLFLVSPLTICHVIDAKSP 279
           NSH+V A IR KL+KS+QT EGEF+PL+Q +++VG+ TG D+LFLVSPL I H I+ +SP
Sbjct: 229 NSHIVEASIRAKLIKSKQTSEGEFIPLNQTDINVGYYTGDDRLFLVSPLIISHEINQQSP 288

Query: 280 FYDLSQRSMQTEQFEIVVILEGIVETTGMTCQARTSYTEDEVLWGHRFFPVISLEEGFFK 339
           F+++S+  +  E+ EIVVILEG+VE TGMTCQAR+SY   E+LWG+RF PV++LE+GF++
Sbjct: 289 FWEISKAQLPKEELEIVVILEGMVEATGMTCQARSSYITSEILWGYRFTPVLTLEDGFYE 348

Query: 340 VDYSQFHATFEVPTPPYSVKEQEEMLLMSSPLIAPAITNSKERHNSVE 387
           VDY+ FH T+E  TP  S KE  E+   +   ++ ++++   +H  +E
Sbjct: 349 VDYNSFHETYETSTPSLSAKELAELASRAELPLSWSVSSKLNQHAELE 396


>gi|24797141 potassium inwardly-rectifying channel J5 [Homo sapiens]
          Length = 419

 Score =  450 bits (1158), Expect = e-126
 Identities = 218/327 (66%), Positives = 268/327 (81%), Gaps = 5/327 (1%)

Query: 40  KKKRQRFVDKNGRCNVQHGNLGSETSRYLSDLFTTLVDLKWRWNLFIFILTYTVAWLFMA 99
           KK RQR+++K+G+CNV HGN+  ET RYLSDLFTTLVDLKWR+NL +F + YTV WLF  
Sbjct: 47  KKPRQRYMEKSGKCNVHHGNV-QETYRYLSDLFTTLVDLKWRFNLLVFTMVYTVTWLFFG 105

Query: 100 SMWWVIAYTRGDLNKAHVGN--YTPCVANVYNFPSAFLFFIETEATIGYGYRYITDKCPE 157
            +WW+IAY RGDL+  HVG+  + PCV N+  F SAFLF IETE TIGYG+R IT+KCPE
Sbjct: 106 FIWWLIAYIRGDLD--HVGDQEWIPCVENLSGFVSAFLFSIETETTIGYGFRVITEKCPE 163

Query: 158 GIILFLFQSILGSIVDAFLIGCMFIKMSQPKKRAETLMFSEHAVISMRDGKLTLMFRVGN 217
           GIIL L Q+ILGSIV+AF++GCMF+K+SQPKKRAETLMFS +AVISMRD KL LMFRVG+
Sbjct: 164 GIILLLVQAILGSIVNAFMVGCMFVKISQPKKRAETLMFSNNAVISMRDEKLCLMFRVGD 223

Query: 218 LRNSHMVSAQIRCKLLKSRQTPEGEFLPLDQLELDVGFSTGADQLFLVSPLTICHVIDAK 277
           LRNSH+V A IR KL+KSRQT EGEF+PL+Q +++VGF TG D+LFLVSPL I H I+ K
Sbjct: 224 LRNSHIVEASIRAKLIKSRQTKEGEFIPLNQTDINVGFDTGDDRLFLVSPLIISHEINQK 283

Query: 278 SPFYDLSQRSMQTEQFEIVVILEGIVETTGMTCQARTSYTEDEVLWGHRFFPVISLEEGF 337
           SPF+++SQ  +  E+FE+VVILEG+VE TGMTCQAR+SY + EVLWGHRF PV++LE+GF
Sbjct: 284 SPFWEMSQAQLHQEEFEVVVILEGMVEATGMTCQARSSYMDTEVLWGHRFTPVLTLEKGF 343

Query: 338 FKVDYSQFHATFEVPTPPYSVKEQEEM 364
           ++VDY+ FH T+E  TP    KE  EM
Sbjct: 344 YEVDYNTFHDTYETNTPSCCAKELAEM 370


>gi|25121970 potassium inwardly-rectifying channel subfamily J9
           [Homo sapiens]
          Length = 393

 Score =  440 bits (1132), Expect = e-123
 Identities = 210/332 (63%), Positives = 267/332 (80%), Gaps = 2/332 (0%)

Query: 33  PQQQLVPKKK-RQRFVDKNGRCNVQHGNLGSETSRYLSDLFTTLVDLKWRWNLFIFILTY 91
           P Q+  P+++ RQR+V+K+GRCNVQ GN+  ET RYL+DLFTTLVDL+WR +L  F+L Y
Sbjct: 10  PGQEEPPRRRGRQRYVEKDGRCNVQQGNV-RETYRYLTDLFTTLVDLQWRLSLLFFVLAY 68

Query: 92  TVAWLFMASMWWVIAYTRGDLNKAHVGNYTPCVANVYNFPSAFLFFIETEATIGYGYRYI 151
            + WLF  ++WW+IAY RGDL       +TPCV N+  F +AFLF IETE TIGYG+R I
Sbjct: 69  ALTWLFFGAIWWLIAYGRGDLEHLEDTAWTPCVNNLNGFVAAFLFSIETETTIGYGHRVI 128

Query: 152 TDKCPEGIILFLFQSILGSIVDAFLIGCMFIKMSQPKKRAETLMFSEHAVISMRDGKLTL 211
           TD+CPEGI+L L Q+ILGS+V+AF++GCMF+K+SQP KRA TL+FS HAV+S+RDG+L L
Sbjct: 129 TDQCPEGIVLLLLQAILGSMVNAFMVGCMFVKISQPNKRAATLVFSSHAVVSLRDGRLCL 188

Query: 212 MFRVGNLRNSHMVSAQIRCKLLKSRQTPEGEFLPLDQLELDVGFSTGADQLFLVSPLTIC 271
           MFRVG+LR+SH+V A IR KL++SRQT EGEF+PL Q +L VGF TG D+LFLVSPL I 
Sbjct: 189 MFRVGDLRSSHIVEASIRAKLIRSRQTLEGEFIPLHQTDLSVGFDTGDDRLFLVSPLVIS 248

Query: 272 HVIDAKSPFYDLSQRSMQTEQFEIVVILEGIVETTGMTCQARTSYTEDEVLWGHRFFPVI 331
           H IDA SPF++ S+R+++ + FEIVVILEG+VE TGMTCQAR+SY  DEVLWGHRF  V+
Sbjct: 249 HEIDAASPFWEASRRALERDDFEIVVILEGMVEATGMTCQARSSYLVDEVLWGHRFTSVL 308

Query: 332 SLEEGFFKVDYSQFHATFEVPTPPYSVKEQEE 363
           +LE+GF++VDY+ FH TFEVPTP  S +E  E
Sbjct: 309 TLEDGFYEVDYASFHETFEVPTPSCSARELAE 340


>gi|4504835 potassium inwardly-rectifying channel J2 [Homo sapiens]
          Length = 427

 Score =  379 bits (973), Expect = e-105
 Identities = 182/348 (52%), Positives = 250/348 (71%), Gaps = 6/348 (1%)

Query: 12  YQVVTTSSSGSGLQPQ----GPGQDPQQQLVPKKKRQRFVDKNGRCNVQHGNLGSETSRY 67
           Y +V++   G  L       G G    +    ++ R RFV K+G CNVQ  N+G +  RY
Sbjct: 9   YSIVSSEEDGMKLATMAVANGFGNGKSKVHTRQQCRSRFVKKDGHCNVQFINVGEKGQRY 68

Query: 68  LSDLFTTLVDLKWRWNLFIFILTYTVAWLFMASMWWVIAYTRGDLNKAHVGNYTPCVANV 127
           L+D+FTT VD++WRW L IF L + ++WLF   ++W+IA   GDL+ +  G    CV+ V
Sbjct: 69  LADIFTTCVDIRWRWMLVIFCLAFVLSWLFFGCVFWLIALLHGDLDASKEGK--ACVSEV 126

Query: 128 YNFPSAFLFFIETEATIGYGYRYITDKCPEGIILFLFQSILGSIVDAFLIGCMFIKMSQP 187
            +F +AFLF IET+ TIGYG+R +TD+CP  + + +FQSI+G I+DAF+IG +  KM++P
Sbjct: 127 NSFTAAFLFSIETQTTIGYGFRCVTDECPIAVFMVVFQSIVGCIIDAFIIGAVMAKMAKP 186

Query: 188 KKRAETLMFSEHAVISMRDGKLTLMFRVGNLRNSHMVSAQIRCKLLKSRQTPEGEFLPLD 247
           KKR ETL+FS +AVI+MRDGKL LM+RVGNLR SH+V A +R +LLKSR T EGE++PLD
Sbjct: 187 KKRNETLVFSHNAVIAMRDGKLCLMWRVGNLRKSHLVEAHVRAQLLKSRITSEGEYIPLD 246

Query: 248 QLELDVGFSTGADQLFLVSPLTICHVIDAKSPFYDLSQRSMQTEQFEIVVILEGIVETTG 307
           Q++++VGF +G D++FLVSP+TI H ID  SP YDLS++ +    FEIVVILEG+VE T 
Sbjct: 247 QIDINVGFDSGIDRIFLVSPITIVHEIDEDSPLYDLSKQDIDNADFEIVVILEGMVEATA 306

Query: 308 MTCQARTSYTEDEVLWGHRFFPVISLEEGFFKVDYSQFHATFEVPTPP 355
           MT Q R+SY  +E+LWGHR+ PV+  E+ ++KVDYS+FH T+EVP  P
Sbjct: 307 MTTQCRSSYLANEILWGHRYEPVLFEEKHYYKVDYSRFHKTYEVPNTP 354


>gi|23110982 potassium inwardly-rectifying channel, subfamily J,
           member 12 [Homo sapiens]
          Length = 433

 Score =  372 bits (955), Expect = e-103
 Identities = 172/325 (52%), Positives = 241/325 (74%), Gaps = 1/325 (0%)

Query: 40  KKKRQRFVDKNGRCNVQHGNLGSETSRYLSDLFTTLVDLKWRWNLFIFILTYTVAWLFMA 99
           ++ R RFV KNG+CN++  N+  ++ RYL+D+FTT VD++WR+ L IF L +  +WL   
Sbjct: 40  RRCRNRFVKKNGQCNIEFANMDEKSQRYLADMFTTCVDIRWRYMLLIFSLAFLASWLLFG 99

Query: 100 SMWWVIAYTRGDLNKAHVGNYTPCVANVYNFPSAFLFFIETEATIGYGYRYITDKCPEGI 159
            ++WVIA   GDL  A     TPCV  V+ F +AFLF IET+ TIGYG R +T++CP  +
Sbjct: 100 IIFWVIAVAHGDLEPAEGRGRTPCVMQVHGFMAAFLFSIETQTTIGYGLRCVTEECPVAV 159

Query: 160 ILFLFQSILGSIVDAFLIGCMFIKMSQPKKRAETLMFSEHAVISMRDGKLTLMFRVGNLR 219
            + + QSI+G I+D+F+IG +  KM++PKKRA+TL+FS +AV+++RDGKL LM+RVGNLR
Sbjct: 160 FMVVAQSIVGCIIDSFMIGAIMAKMARPKKRAQTLLFSHNAVVALRDGKLCLMWRVGNLR 219

Query: 220 NSHMVSAQIRCKLLKSRQTPEGEFLPLDQLELDVGFSTGADQLFLVSPLTICHVIDAKSP 279
            SH+V A +R +L+K R T EGE++PLDQ+++DVGF  G D++FLVSP+TI H ID  SP
Sbjct: 220 KSHIVEAHVRAQLIKPRVTEEGEYIPLDQIDIDVGFDKGLDRIFLVSPITILHEIDEASP 279

Query: 280 FYDLSQRSMQTEQFEIVVILEGIVETTGMTCQARTSYTEDEVLWGHRFFPVISLEEGFFK 339
            + +S++ ++T+ FEIVVILEG+VE T MT QAR+SY  +E+LWGHRF PV+  E+  +K
Sbjct: 280 LFGISRQDLETDDFEIVVILEGMVEATAMTTQARSSYLANEILWGHRFEPVLFEEKNQYK 339

Query: 340 VDYSQFHATFEVP-TPPYSVKEQEE 363
           +DYS FH T+EVP TP  S K+  E
Sbjct: 340 IDYSHFHKTYEVPSTPRCSAKDLVE 364


>gi|239758082 PREDICTED: similar to thyrotoxic periodic paralysis
           susceptibility ion channel [Homo sapiens]
          Length = 433

 Score =  366 bits (940), Expect = e-101
 Identities = 171/325 (52%), Positives = 238/325 (73%), Gaps = 1/325 (0%)

Query: 40  KKKRQRFVDKNGRCNVQHGNLGSETSRYLSDLFTTLVDLKWRWNLFIFILTYTVAWLFMA 99
           ++ R RFV KNG+CN+   N+  ++ RYL+D+FTT VD++WR+ L IF L +  +WL   
Sbjct: 40  RRCRNRFVKKNGQCNIAFANMDEKSQRYLADMFTTCVDIRWRYMLLIFSLAFLASWLLFG 99

Query: 100 SMWWVIAYTRGDLNKAHVGNYTPCVANVYNFPSAFLFFIETEATIGYGYRYITDKCPEGI 159
            ++WVIA   GDL  A     TPCV  V+ F +AFLF IET+ TIGYG R +T++C   +
Sbjct: 100 VIFWVIAVAHGDLEPAEGHGRTPCVMQVHGFMAAFLFSIETQTTIGYGLRCVTEECLVAV 159

Query: 160 ILFLFQSILGSIVDAFLIGCMFIKMSQPKKRAETLMFSEHAVISMRDGKLTLMFRVGNLR 219
            + + QSI+G I+D+F+IG +  KM++PKKRA TL+FS +AV+++RDGKL LM+RVGNLR
Sbjct: 160 FMVVAQSIVGCIIDSFMIGAIMAKMARPKKRAHTLLFSHNAVVALRDGKLCLMWRVGNLR 219

Query: 220 NSHMVSAQIRCKLLKSRQTPEGEFLPLDQLELDVGFSTGADQLFLVSPLTICHVIDAKSP 279
            SH+V A +R +L+K R T EGE++PLDQ+++DVGF  G D++FLVSP+TI H ID  SP
Sbjct: 220 KSHIVEAHVRAQLIKPRVTEEGEYIPLDQIDIDVGFDKGLDRIFLVSPITILHEIDEASP 279

Query: 280 FYDLSQRSMQTEQFEIVVILEGIVETTGMTCQARTSYTEDEVLWGHRFFPVISLEEGFFK 339
            + +S++ ++T+ FEIVVILEG+VE T MT QAR+SY  +E+LWGHRF PV+  E+  +K
Sbjct: 280 LFGISRQDLETDDFEIVVILEGMVEATAMTTQARSSYLANEILWGHRFEPVLFEEKNQYK 339

Query: 340 VDYSQFHATFEVP-TPPYSVKEQEE 363
           +DYS FH T+EVP TP  S K+  E
Sbjct: 340 IDYSHFHKTYEVPSTPRCSAKDLVE 364


>gi|4826798 potassium inwardly-rectifying channel J4 [Homo sapiens]
          Length = 445

 Score =  358 bits (918), Expect = 8e-99
 Identities = 177/364 (48%), Positives = 245/364 (67%), Gaps = 17/364 (4%)

Query: 28  GPGQDPQQQLVPKKKRQRFVDKNGRCNVQHGNLGSETSRYLSDLFTTLVDLKWRWNLFIF 87
           G  ++ Q  +  +K+R RFV KNG+CNV   NL +++ RY++D+FTT VD +WR+ L IF
Sbjct: 3   GHSRNGQAHVPRRKRRNRFVKKNGQCNVYFANLSNKSQRYMADIFTTCVDTRWRYMLMIF 62

Query: 88  ILTYTVAWLFMASMWWVIAYTRGDLNK-----------AHVGNYTP-----CVANVYNFP 131
              + V+WLF   ++W IA+  GDL             A  G   P     C+ +V  F 
Sbjct: 63  SAAFLVSWLFFGLLFWCIAFFHGDLEASPGVPAAGGPAAGGGGAAPVAPKPCIMHVNGFL 122

Query: 132 SAFLFFIETEATIGYGYRYITDKCPEGIILFLFQSILGSIVDAFLIGCMFIKMSQPKKRA 191
            AFLF +ET+ TIGYG+R +T++CP  +I  + QSI+G ++D+F+IG +  KM++PKKRA
Sbjct: 123 GAFLFSVETQTTIGYGFRCVTEECPLAVIAVVVQSIVGCVIDSFMIGTIMAKMARPKKRA 182

Query: 192 ETLMFSEHAVISMRDGKLTLMFRVGNLRNSHMVSAQIRCKLLKSRQTPEGEFLPLDQLEL 251
           +TL+FS HAVIS+RDGKL LM+RVGNLR SH+V A +R +L+K   T EGE+LPLDQ +L
Sbjct: 183 QTLLFSHHAVISVRDGKLCLMWRVGNLRKSHIVEAHVRAQLIKPYMTQEGEYLPLDQRDL 242

Query: 252 DVGFSTGADQLFLVSPLTICHVIDAKSPFYDLSQRSMQTEQFEIVVILEGIVETTGMTCQ 311
           +VG+  G D++FLVSP+ I H ID  SP Y + +  +++E FEIVVILEG+VE T MT Q
Sbjct: 243 NVGYDIGLDRIFLVSPIIIVHEIDEDSPLYGMGKEELESEDFEIVVILEGMVEATAMTTQ 302

Query: 312 ARTSYTEDEVLWGHRFFPVISLEEGFFKVDYSQFHATFEVP-TPPYSVKEQEEMLLMSSP 370
           AR+SY   E+LWGHRF PV+  E+  +KVDYS+FH T+EV  TP  S +E +E  +   P
Sbjct: 303 ARSSYLASEILWGHRFEPVVFEEKSHYKVDYSRFHKTYEVAGTPCCSARELQESKITVLP 362

Query: 371 LIAP 374
              P
Sbjct: 363 APPP 366


>gi|23110984 potassium inwardly-rectifying channel J4 [Homo sapiens]
          Length = 445

 Score =  358 bits (918), Expect = 8e-99
 Identities = 177/364 (48%), Positives = 245/364 (67%), Gaps = 17/364 (4%)

Query: 28  GPGQDPQQQLVPKKKRQRFVDKNGRCNVQHGNLGSETSRYLSDLFTTLVDLKWRWNLFIF 87
           G  ++ Q  +  +K+R RFV KNG+CNV   NL +++ RY++D+FTT VD +WR+ L IF
Sbjct: 3   GHSRNGQAHVPRRKRRNRFVKKNGQCNVYFANLSNKSQRYMADIFTTCVDTRWRYMLMIF 62

Query: 88  ILTYTVAWLFMASMWWVIAYTRGDLNK-----------AHVGNYTP-----CVANVYNFP 131
              + V+WLF   ++W IA+  GDL             A  G   P     C+ +V  F 
Sbjct: 63  SAAFLVSWLFFGLLFWCIAFFHGDLEASPGVPAAGGPAAGGGGAAPVAPKPCIMHVNGFL 122

Query: 132 SAFLFFIETEATIGYGYRYITDKCPEGIILFLFQSILGSIVDAFLIGCMFIKMSQPKKRA 191
            AFLF +ET+ TIGYG+R +T++CP  +I  + QSI+G ++D+F+IG +  KM++PKKRA
Sbjct: 123 GAFLFSVETQTTIGYGFRCVTEECPLAVIAVVVQSIVGCVIDSFMIGTIMAKMARPKKRA 182

Query: 192 ETLMFSEHAVISMRDGKLTLMFRVGNLRNSHMVSAQIRCKLLKSRQTPEGEFLPLDQLEL 251
           +TL+FS HAVIS+RDGKL LM+RVGNLR SH+V A +R +L+K   T EGE+LPLDQ +L
Sbjct: 183 QTLLFSHHAVISVRDGKLCLMWRVGNLRKSHIVEAHVRAQLIKPYMTQEGEYLPLDQRDL 242

Query: 252 DVGFSTGADQLFLVSPLTICHVIDAKSPFYDLSQRSMQTEQFEIVVILEGIVETTGMTCQ 311
           +VG+  G D++FLVSP+ I H ID  SP Y + +  +++E FEIVVILEG+VE T MT Q
Sbjct: 243 NVGYDIGLDRIFLVSPIIIVHEIDEDSPLYGMGKEELESEDFEIVVILEGMVEATAMTTQ 302

Query: 312 ARTSYTEDEVLWGHRFFPVISLEEGFFKVDYSQFHATFEVP-TPPYSVKEQEEMLLMSSP 370
           AR+SY   E+LWGHRF PV+  E+  +KVDYS+FH T+EV  TP  S +E +E  +   P
Sbjct: 303 ARSSYLASEILWGHRFEPVVFEEKSHYKVDYSRFHKTYEVAGTPCCSARELQESKITVLP 362

Query: 371 LIAP 374
              P
Sbjct: 363 APPP 366


>gi|239757993 PREDICTED: similar to inward rectifying K+ channel
           negative regulator Kir2.2v isoform 1 [Homo sapiens]
          Length = 432

 Score =  354 bits (909), Expect = 9e-98
 Identities = 172/355 (48%), Positives = 242/355 (68%), Gaps = 4/355 (1%)

Query: 12  YQVVTTSSSGSGLQPQGPGQDPQQQLVPKKKR--QRFVDKNGRCNVQHGNLGSETSRYLS 69
           Y +V++   G  L             V  ++R   RFV KNG+CN++  N+  ++ RYL+
Sbjct: 10  YSIVSSEEDGLHLVTMSGANGFGNGKVHTRRRCHNRFVKKNGQCNIEFANMDEKSQRYLA 69

Query: 70  DLFTTLVDLKWRWNLFIFILTYTVAWLFMASMWWVIAYTRGDLNKAHVGNYTPCVANVYN 129
           D+FTT VD++WR+ L IF L +  +WL    ++WVIA   GDL  A     TPCV  V+ 
Sbjct: 70  DIFTTCVDIRWRYMLLIFSLAFLASWLLFGVIFWVIAVAHGDLEPAEGRGRTPCVMQVHG 129

Query: 130 FPSAFLFFIETEATIGYGYRYITDKCPEGIILFLFQSILGSIVDAFLIGCMFIKMSQPKK 189
           F +AFLF I+T+ TI YG R +T++CP  + + + QSI+G I+++F+IG +  KM +PKK
Sbjct: 130 FMAAFLFSIKTQNTISYGLRCVTEECPVAVFMVVAQSIVGCIINSFMIGAIMAKMVRPKK 189

Query: 190 RAETLMFSEHAVISMRDGKLTLMFRVGNLRNSHMVSAQIRCKLLKSRQTPEGEFLPLDQL 249
           RA+TL+FS +AV+++RDGKL  M+RVGNLR SH+V A +R +L+K R T EGE++PLDQ+
Sbjct: 190 RAQTLLFSHNAVVALRDGKLCFMWRVGNLRKSHIVEAHVRAQLIKPRVTKEGEYIPLDQI 249

Query: 250 ELDVGFSTGADQLFLVSPLTICHVIDAKSPFYDLSQRSMQTEQFEIVVILEGIVETTGMT 309
           ++DVGF  G D  FLVSP+TI H ID  SP + +S++ +Q + FEIV+ILEGIVE T MT
Sbjct: 250 DIDVGFDKGLDHSFLVSPITILHEIDEASPLFGISRQDLQMDDFEIVIILEGIVEATAMT 309

Query: 310 CQARTSYTEDEVLWGHRFFPVISLEEGFFKVDYSQFHATFEVP-TPPYSVKEQEE 363
            QAR+SY  +E+LWGHRF PV+  E+  +K+DY  FH T+EVP TP  S K+  E
Sbjct: 310 TQARSSYLANEILWGHRFEPVL-FEKNQYKIDYLHFHKTYEVPSTPRCSAKDLVE 363


>gi|239757991 PREDICTED: similar to inward rectifying K+ channel
           negative regulator Kir2.2v isoform 2 [Homo sapiens]
          Length = 534

 Score =  354 bits (909), Expect = 9e-98
 Identities = 172/355 (48%), Positives = 242/355 (68%), Gaps = 4/355 (1%)

Query: 12  YQVVTTSSSGSGLQPQGPGQDPQQQLVPKKKR--QRFVDKNGRCNVQHGNLGSETSRYLS 69
           Y +V++   G  L             V  ++R   RFV KNG+CN++  N+  ++ RYL+
Sbjct: 112 YSIVSSEEDGLHLVTMSGANGFGNGKVHTRRRCHNRFVKKNGQCNIEFANMDEKSQRYLA 171

Query: 70  DLFTTLVDLKWRWNLFIFILTYTVAWLFMASMWWVIAYTRGDLNKAHVGNYTPCVANVYN 129
           D+FTT VD++WR+ L IF L +  +WL    ++WVIA   GDL  A     TPCV  V+ 
Sbjct: 172 DIFTTCVDIRWRYMLLIFSLAFLASWLLFGVIFWVIAVAHGDLEPAEGRGRTPCVMQVHG 231

Query: 130 FPSAFLFFIETEATIGYGYRYITDKCPEGIILFLFQSILGSIVDAFLIGCMFIKMSQPKK 189
           F +AFLF I+T+ TI YG R +T++CP  + + + QSI+G I+++F+IG +  KM +PKK
Sbjct: 232 FMAAFLFSIKTQNTISYGLRCVTEECPVAVFMVVAQSIVGCIINSFMIGAIMAKMVRPKK 291

Query: 190 RAETLMFSEHAVISMRDGKLTLMFRVGNLRNSHMVSAQIRCKLLKSRQTPEGEFLPLDQL 249
           RA+TL+FS +AV+++RDGKL  M+RVGNLR SH+V A +R +L+K R T EGE++PLDQ+
Sbjct: 292 RAQTLLFSHNAVVALRDGKLCFMWRVGNLRKSHIVEAHVRAQLIKPRVTKEGEYIPLDQI 351

Query: 250 ELDVGFSTGADQLFLVSPLTICHVIDAKSPFYDLSQRSMQTEQFEIVVILEGIVETTGMT 309
           ++DVGF  G D  FLVSP+TI H ID  SP + +S++ +Q + FEIV+ILEGIVE T MT
Sbjct: 352 DIDVGFDKGLDHSFLVSPITILHEIDEASPLFGISRQDLQMDDFEIVIILEGIVEATAMT 411

Query: 310 CQARTSYTEDEVLWGHRFFPVISLEEGFFKVDYSQFHATFEVP-TPPYSVKEQEE 363
            QAR+SY  +E+LWGHRF PV+  E+  +K+DY  FH T+EVP TP  S K+  E
Sbjct: 412 TQARSSYLANEILWGHRFEPVL-FEKNQYKIDYLHFHKTYEVPSTPRCSAKDLVE 465


>gi|239751249 PREDICTED: hypothetical protein XP_002347768 [Homo
           sapiens]
          Length = 432

 Score =  354 bits (909), Expect = 9e-98
 Identities = 172/355 (48%), Positives = 242/355 (68%), Gaps = 4/355 (1%)

Query: 12  YQVVTTSSSGSGLQPQGPGQDPQQQLVPKKKR--QRFVDKNGRCNVQHGNLGSETSRYLS 69
           Y +V++   G  L             V  ++R   RFV KNG+CN++  N+  ++ RYL+
Sbjct: 10  YSIVSSEEDGLHLVTMSGANGFGNGKVHTRRRCHNRFVKKNGQCNIEFANMDEKSQRYLA 69

Query: 70  DLFTTLVDLKWRWNLFIFILTYTVAWLFMASMWWVIAYTRGDLNKAHVGNYTPCVANVYN 129
           D+FTT VD++WR+ L IF L +  +WL    ++WVIA   GDL  A     TPCV  V+ 
Sbjct: 70  DIFTTCVDIRWRYMLLIFSLAFLASWLLFGVIFWVIAVAHGDLEPAEGRGRTPCVMQVHG 129

Query: 130 FPSAFLFFIETEATIGYGYRYITDKCPEGIILFLFQSILGSIVDAFLIGCMFIKMSQPKK 189
           F +AFLF I+T+ TI YG R +T++CP  + + + QSI+G I+++F+IG +  KM +PKK
Sbjct: 130 FMAAFLFSIKTQNTISYGLRCVTEECPVAVFMVVAQSIVGCIINSFMIGAIMAKMVRPKK 189

Query: 190 RAETLMFSEHAVISMRDGKLTLMFRVGNLRNSHMVSAQIRCKLLKSRQTPEGEFLPLDQL 249
           RA+TL+FS +AV+++RDGKL  M+RVGNLR SH+V A +R +L+K R T EGE++PLDQ+
Sbjct: 190 RAQTLLFSHNAVVALRDGKLCFMWRVGNLRKSHIVEAHVRAQLIKPRVTKEGEYIPLDQI 249

Query: 250 ELDVGFSTGADQLFLVSPLTICHVIDAKSPFYDLSQRSMQTEQFEIVVILEGIVETTGMT 309
           ++DVGF  G D  FLVSP+TI H ID  SP + +S++ +Q + FEIV+ILEGIVE T MT
Sbjct: 250 DIDVGFDKGLDHSFLVSPITILHEIDEASPLFGISRQDLQMDDFEIVIILEGIVEATAMT 309

Query: 310 CQARTSYTEDEVLWGHRFFPVISLEEGFFKVDYSQFHATFEVP-TPPYSVKEQEE 363
            QAR+SY  +E+LWGHRF PV+  E+  +K+DY  FH T+EVP TP  S K+  E
Sbjct: 310 TQARSSYLANEILWGHRFEPVL-FEKNQYKIDYLHFHKTYEVPSTPRCSAKDLVE 363


>gi|7019439 potassium inwardly-rectifying channel J14 [Homo sapiens]
          Length = 436

 Score =  343 bits (880), Expect = 2e-94
 Identities = 176/366 (48%), Positives = 242/366 (66%), Gaps = 8/366 (2%)

Query: 3   ALRRKFG----DDYQVVTTSSSGSGLQPQGPGQDPQQQLVPKKKRQRFVDKNGRCNVQHG 58
           ALRR  G     D +      +G GL   G    P Q  V ++ R RFV K+G CNV+  
Sbjct: 6   ALRRLSGALDSGDSRAGDEEEAGPGLCRNGWAPAPVQSPVGRR-RGRFVKKDGHCNVRFV 64

Query: 59  NLGSETSRYLSDLFTTLVDLKWRWNLFIFILTYTVAWLFMASMWWVIAYTRGDLNKAHVG 118
           NLG + +RYLSDLFTT VD++WRW   +F  ++  +WL     +W+IA   GDL  A   
Sbjct: 65  NLGGQGARYLSDLFTTCVDVRWRWMCLLFSCSFLASWLLFGLAFWLIASLHGDL--AAPP 122

Query: 119 NYTPCVANVYNFPSAFLFFIETEATIGYGYRYITDKCPEGIILFLFQSILGSIVDAFLIG 178
              PC ++V +F +AFLF +ET+ +IGYG R +T++CP  +   + Q I G ++DAF++G
Sbjct: 123 PPAPCFSHVASFLAAFLFALETQTSIGYGVRSVTEECPAAVAAVVLQCIAGCVLDAFVVG 182

Query: 179 CMFIKMSQPKKRAETLMFSEHAVISMRDGKLTLMFRVGNLRNSHMVSAQIRCKLLKSRQT 238
            +  KM++PKKR ETL+FSE+AV+++RD +L LM+RVGNLR SH+V A +R +LL+ R T
Sbjct: 183 AVMAKMAKPKKRNETLVFSENAVVALRDHRLCLMWRVGNLRRSHLVEAHVRAQLLQPRVT 242

Query: 239 PEGEFLPLDQLELDVGFSTGADQLFLVSPLTICHVIDAKSPFYDLSQRSMQTEQFEIVVI 298
           PEGE++PLD  ++DVGF  G D++FLVSP+TI H ID+ SP Y+L +  +    FE+VVI
Sbjct: 243 PEGEYIPLDHQDVDVGFDGGTDRIFLVSPITIVHEIDSASPLYELGRAELARADFELVVI 302

Query: 299 LEGIVETTGMTCQARTSYTEDEVLWGHRFFPVISLEEGFFKVDYSQFHATFEVP-TPPYS 357
           LEG+VE T MT Q R+SY   E+LWGHRF PV+      ++VDY  FH T+EVP TP  S
Sbjct: 303 LEGMVEATAMTTQCRSSYLPGELLWGHRFEPVLFQRGSQYEVDYRHFHRTYEVPGTPVCS 362

Query: 358 VKEQEE 363
            KE +E
Sbjct: 363 AKELDE 368


>gi|25777635 potassium inwardly-rectifying channel J14 [Homo
           sapiens]
          Length = 436

 Score =  343 bits (880), Expect = 2e-94
 Identities = 176/366 (48%), Positives = 242/366 (66%), Gaps = 8/366 (2%)

Query: 3   ALRRKFG----DDYQVVTTSSSGSGLQPQGPGQDPQQQLVPKKKRQRFVDKNGRCNVQHG 58
           ALRR  G     D +      +G GL   G    P Q  V ++ R RFV K+G CNV+  
Sbjct: 6   ALRRLSGALDSGDSRAGDEEEAGPGLCRNGWAPAPVQSPVGRR-RGRFVKKDGHCNVRFV 64

Query: 59  NLGSETSRYLSDLFTTLVDLKWRWNLFIFILTYTVAWLFMASMWWVIAYTRGDLNKAHVG 118
           NLG + +RYLSDLFTT VD++WRW   +F  ++  +WL     +W+IA   GDL  A   
Sbjct: 65  NLGGQGARYLSDLFTTCVDVRWRWMCLLFSCSFLASWLLFGLAFWLIASLHGDL--AAPP 122

Query: 119 NYTPCVANVYNFPSAFLFFIETEATIGYGYRYITDKCPEGIILFLFQSILGSIVDAFLIG 178
              PC ++V +F +AFLF +ET+ +IGYG R +T++CP  +   + Q I G ++DAF++G
Sbjct: 123 PPAPCFSHVASFLAAFLFALETQTSIGYGVRSVTEECPAAVAAVVLQCIAGCVLDAFVVG 182

Query: 179 CMFIKMSQPKKRAETLMFSEHAVISMRDGKLTLMFRVGNLRNSHMVSAQIRCKLLKSRQT 238
            +  KM++PKKR ETL+FSE+AV+++RD +L LM+RVGNLR SH+V A +R +LL+ R T
Sbjct: 183 AVMAKMAKPKKRNETLVFSENAVVALRDHRLCLMWRVGNLRRSHLVEAHVRAQLLQPRVT 242

Query: 239 PEGEFLPLDQLELDVGFSTGADQLFLVSPLTICHVIDAKSPFYDLSQRSMQTEQFEIVVI 298
           PEGE++PLD  ++DVGF  G D++FLVSP+TI H ID+ SP Y+L +  +    FE+VVI
Sbjct: 243 PEGEYIPLDHQDVDVGFDGGTDRIFLVSPITIVHEIDSASPLYELGRAELARADFELVVI 302

Query: 299 LEGIVETTGMTCQARTSYTEDEVLWGHRFFPVISLEEGFFKVDYSQFHATFEVP-TPPYS 357
           LEG+VE T MT Q R+SY   E+LWGHRF PV+      ++VDY  FH T+EVP TP  S
Sbjct: 303 LEGMVEATAMTTQCRSSYLPGELLWGHRFEPVLFQRGSQYEVDYRHFHRTYEVPGTPVCS 362

Query: 358 VKEQEE 363
            KE +E
Sbjct: 363 AKELDE 368


>gi|62388888 potassium inwardly-rectifying channel J11 [Homo
           sapiens]
          Length = 390

 Score =  330 bits (846), Expect = 2e-90
 Identities = 156/325 (48%), Positives = 230/325 (70%), Gaps = 3/325 (0%)

Query: 40  KKKRQRFVDKNGRCNVQHGNLGSETSRYLSDLFTTLVDLKWRWNLFIFILTYTVAWLFMA 99
           +++R RFV K G CNV H N+  E  R+L D+FTTLVDLKW   L IF +++  +WL  A
Sbjct: 29  RQRRARFVSKKGNCNVAHKNI-REQGRFLQDVFTTLVDLKWPHTLLIFTMSFLCSWLLFA 87

Query: 100 SMWWVIAYTRGDLNKAHVGNYTPCVANVYNFPSAFLFFIETEATIGYGYRYITDKCPEGI 159
             WW+IA+  GDL  +  G   PCV ++++F SAFLF IE + TIG+G R +T++CP  I
Sbjct: 88  MAWWLIAFAHGDLAPSE-GTAEPCVTSIHSFSSAFLFSIEVQVTIGFGGRMVTEECPLAI 146

Query: 160 ILFLFQSILGSIVDAFLIGCMFIKMSQPKKRAETLMFSEHAVISMRDGKLTLMFRVGNLR 219
           ++ + Q+I+G +++A ++GC+F+K +Q  +RAETL+FS+HAVI++R G+L  M RVG+LR
Sbjct: 147 LILIVQNIVGLMINAIMLGCIFMKTAQAHRRAETLIFSKHAVIALRHGRLCFMLRVGDLR 206

Query: 220 NSHMVSAQIRCKLLKSRQTPEGEFLPLDQLELDVGFSTGADQLFLVSPLTICHVIDAKSP 279
            S ++SA I  ++++   +PEGE +PL Q+++ +    G + +FLV+PL I HVIDA SP
Sbjct: 207 KSMIISATIHMQVVRKTTSPEGEVVPLHQVDIPMENGVGGNSIFLVAPLIIYHVIDANSP 266

Query: 280 FYDLSQRSMQTEQ-FEIVVILEGIVETTGMTCQARTSYTEDEVLWGHRFFPVISLEEGFF 338
            YDL+   +   Q  EI+VILEG+VETTG+T QARTSY  DE+LWG RF P+++ E+G +
Sbjct: 267 LYDLAPSDLHHHQDLEIIVILEGVVETTGITTQARTSYLADEILWGQRFVPIVAEEDGRY 326

Query: 339 KVDYSQFHATFEVPTPPYSVKEQEE 363
            VDYS+F  T +VPTP  + ++ +E
Sbjct: 327 SVDYSKFGNTVKVPTPLCTARQLDE 351


>gi|4826802 potassium inwardly-rectifying channel J8 [Homo sapiens]
          Length = 424

 Score =  329 bits (844), Expect = 3e-90
 Identities = 162/356 (45%), Positives = 241/356 (67%), Gaps = 14/356 (3%)

Query: 43  RQRFVDKNGRCNVQHGNLGSETSRYLSDLFTTLVDLKWRWNLFIFILTYTVAWLFMASMW 102
           + RF+ K+G CN+ H N+  E  R+L D+FTTLVDLKWR  L IF +++  +WL  A MW
Sbjct: 33  KARFIAKSGACNLAHKNI-REQGRFLQDIFTTLVDLKWRHTLVIFTMSFLCSWLLFAIMW 91

Query: 103 WVIAYTRGDL---------NKAHVGNYTPCVANVYNFPSAFLFFIETEATIGYGYRYITD 153
           W++A+  GD+          K+ + + T CV NV +F SAFLF IE + TIG+G R +T+
Sbjct: 92  WLVAFAHGDIYAYMEKSGMEKSGLES-TVCVTNVRSFTSAFLFSIEVQVTIGFGGRMMTE 150

Query: 154 KCPEGIILFLFQSILGSIVDAFLIGCMFIKMSQPKKRAETLMFSEHAVISMRDGKLTLMF 213
           +CP  I + + Q+I+G I++A ++GC+F+K +Q  +RAETL+FS HAVI++R+GKL  MF
Sbjct: 151 ECPLAITVLILQNIVGLIINAVMLGCIFMKTAQAHRRAETLIFSRHAVIAVRNGKLCFMF 210

Query: 214 RVGNLRNSHMVSAQIRCKLLKSRQTPEGEFLPLDQLELDVGFSTGADQLFLVSPLTICHV 273
           RVG+LR S ++SA +R +++K   TPEGE +P+ QL++ V     ++ +FLV+PL ICHV
Sbjct: 211 RVGDLRKSMIISASVRIQVVKKTTTPEGEVVPIHQLDIPVDNPIESNNIFLVAPLIICHV 270

Query: 274 IDAKSPFYDLSQRSMQTEQFEIVVILEGIVETTGMTCQARTSYTEDEVLWGHRFFPVISL 333
           ID +SP YD+S   +  +  E++VILEG+VETTG+T QARTSY  +E+ WGHRF  +++ 
Sbjct: 271 IDKRSPLYDISATDLANQDLEVIVILEGVVETTGITTQARTSYIAEEIQWGHRFVSIVTE 330

Query: 334 EEGFFKVDYSQFHATFEVPTPPYSVKEQEE---MLLMSSPLIAPAITNSKERHNSV 386
           EEG + VDYS+F  T +V  P  S +E +E   +L+ +      +  NS  + NS+
Sbjct: 331 EEGVYSVDYSKFGNTVKVAAPRCSARELDEKPSILIQTLQKSELSHQNSLRKRNSM 386


>gi|24497471 potassium inwardly-rectifying channel J1 isoform b
           [Homo sapiens]
          Length = 372

 Score =  311 bits (798), Expect = 7e-85
 Identities = 151/318 (47%), Positives = 221/318 (69%), Gaps = 5/318 (1%)

Query: 41  KKRQRFVDKNGRCNVQHGNLGSETSRYLS--DLFTTLVDLKWRWNLFIFILTYTVAWLFM 98
           ++R R V K+GRCN++ GN+ ++ SR++   D++TT++DLKWR+ + IFI  +  +W F 
Sbjct: 18  RQRARLVSKDGRCNIEFGNVEAQ-SRFIFFVDIWTTVLDLKWRYKMTIFITAFLGSWFFF 76

Query: 99  ASMWWVIAYTRGDLNKAHVG-NYTPCVANVYNFPSAFLFFIETEATIGYGYRYITDKCPE 157
             +W+ +AY   DL + H   N+TPCV N+    SAFLF +ET+ TIGYG+R +T++C  
Sbjct: 77  GLLWYAVAYIHKDLPEFHPSANHTPCVENINGLTSAFLFSLETQVTIGYGFRCVTEQCAT 136

Query: 158 GIILFLFQSILGSIVDAFLIGCMFIKMSQPKKRAETLMFSEHAVISMRDGKLTLMFRVGN 217
            I L +FQSILG I+++F+ G +  K+S+PKKRA+T+ FS++AVIS R GKL L+ RV N
Sbjct: 137 AIFLLIFQSILGVIINSFMCGAILAKISRPKKRAKTITFSKNAVISKRGGKLCLLIRVAN 196

Query: 218 LRNSHMVSAQIRCKLLKSRQTPEGEFLPLDQLELDVGFSTGADQLFLVSPLTICHVIDAK 277
           LR S ++ + I  KLLK+  TPEGE + LDQ+ ++     G + LF +SPLTI HVID  
Sbjct: 197 LRKSLLIGSHIYGKLLKTTVTPEGETIILDQININFVVDAGNENLFFISPLTIYHVIDHN 256

Query: 278 SPFYDLSQRSMQTEQFEIVVILEGIVETTGMTCQARTSYTEDEVLWGHRFFPVIS-LEEG 336
           SPF+ ++  ++  + FE+VV L+G VE+T  TCQ RTSY  +EVLWG+RF P++S  +EG
Sbjct: 257 SPFFHMAAETLLQQDFELVVFLDGTVESTSATCQVRTSYVPEEVLWGYRFAPIVSKTKEG 316

Query: 337 FFKVDYSQFHATFEVPTP 354
            ++VD+  F  T EV TP
Sbjct: 317 KYRVDFHNFSKTVEVETP 334


>gi|24497467 potassium inwardly-rectifying channel J1 isoform b
           [Homo sapiens]
          Length = 372

 Score =  311 bits (798), Expect = 7e-85
 Identities = 151/318 (47%), Positives = 221/318 (69%), Gaps = 5/318 (1%)

Query: 41  KKRQRFVDKNGRCNVQHGNLGSETSRYLS--DLFTTLVDLKWRWNLFIFILTYTVAWLFM 98
           ++R R V K+GRCN++ GN+ ++ SR++   D++TT++DLKWR+ + IFI  +  +W F 
Sbjct: 18  RQRARLVSKDGRCNIEFGNVEAQ-SRFIFFVDIWTTVLDLKWRYKMTIFITAFLGSWFFF 76

Query: 99  ASMWWVIAYTRGDLNKAHVG-NYTPCVANVYNFPSAFLFFIETEATIGYGYRYITDKCPE 157
             +W+ +AY   DL + H   N+TPCV N+    SAFLF +ET+ TIGYG+R +T++C  
Sbjct: 77  GLLWYAVAYIHKDLPEFHPSANHTPCVENINGLTSAFLFSLETQVTIGYGFRCVTEQCAT 136

Query: 158 GIILFLFQSILGSIVDAFLIGCMFIKMSQPKKRAETLMFSEHAVISMRDGKLTLMFRVGN 217
            I L +FQSILG I+++F+ G +  K+S+PKKRA+T+ FS++AVIS R GKL L+ RV N
Sbjct: 137 AIFLLIFQSILGVIINSFMCGAILAKISRPKKRAKTITFSKNAVISKRGGKLCLLIRVAN 196

Query: 218 LRNSHMVSAQIRCKLLKSRQTPEGEFLPLDQLELDVGFSTGADQLFLVSPLTICHVIDAK 277
           LR S ++ + I  KLLK+  TPEGE + LDQ+ ++     G + LF +SPLTI HVID  
Sbjct: 197 LRKSLLIGSHIYGKLLKTTVTPEGETIILDQININFVVDAGNENLFFISPLTIYHVIDHN 256

Query: 278 SPFYDLSQRSMQTEQFEIVVILEGIVETTGMTCQARTSYTEDEVLWGHRFFPVIS-LEEG 336
           SPF+ ++  ++  + FE+VV L+G VE+T  TCQ RTSY  +EVLWG+RF P++S  +EG
Sbjct: 257 SPFFHMAAETLLQQDFELVVFLDGTVESTSATCQVRTSYVPEEVLWGYRFAPIVSKTKEG 316

Query: 337 FFKVDYSQFHATFEVPTP 354
            ++VD+  F  T EV TP
Sbjct: 317 KYRVDFHNFSKTVEVETP 334


>gi|4504837 potassium inwardly-rectifying channel J1 isoform a [Homo
           sapiens]
          Length = 391

 Score =  311 bits (798), Expect = 7e-85
 Identities = 151/318 (47%), Positives = 221/318 (69%), Gaps = 5/318 (1%)

Query: 41  KKRQRFVDKNGRCNVQHGNLGSETSRYLS--DLFTTLVDLKWRWNLFIFILTYTVAWLFM 98
           ++R R V K+GRCN++ GN+ ++ SR++   D++TT++DLKWR+ + IFI  +  +W F 
Sbjct: 37  RQRARLVSKDGRCNIEFGNVEAQ-SRFIFFVDIWTTVLDLKWRYKMTIFITAFLGSWFFF 95

Query: 99  ASMWWVIAYTRGDLNKAHVG-NYTPCVANVYNFPSAFLFFIETEATIGYGYRYITDKCPE 157
             +W+ +AY   DL + H   N+TPCV N+    SAFLF +ET+ TIGYG+R +T++C  
Sbjct: 96  GLLWYAVAYIHKDLPEFHPSANHTPCVENINGLTSAFLFSLETQVTIGYGFRCVTEQCAT 155

Query: 158 GIILFLFQSILGSIVDAFLIGCMFIKMSQPKKRAETLMFSEHAVISMRDGKLTLMFRVGN 217
            I L +FQSILG I+++F+ G +  K+S+PKKRA+T+ FS++AVIS R GKL L+ RV N
Sbjct: 156 AIFLLIFQSILGVIINSFMCGAILAKISRPKKRAKTITFSKNAVISKRGGKLCLLIRVAN 215

Query: 218 LRNSHMVSAQIRCKLLKSRQTPEGEFLPLDQLELDVGFSTGADQLFLVSPLTICHVIDAK 277
           LR S ++ + I  KLLK+  TPEGE + LDQ+ ++     G + LF +SPLTI HVID  
Sbjct: 216 LRKSLLIGSHIYGKLLKTTVTPEGETIILDQININFVVDAGNENLFFISPLTIYHVIDHN 275

Query: 278 SPFYDLSQRSMQTEQFEIVVILEGIVETTGMTCQARTSYTEDEVLWGHRFFPVIS-LEEG 336
           SPF+ ++  ++  + FE+VV L+G VE+T  TCQ RTSY  +EVLWG+RF P++S  +EG
Sbjct: 276 SPFFHMAAETLLQQDFELVVFLDGTVESTSATCQVRTSYVPEEVLWGYRFAPIVSKTKEG 335

Query: 337 FFKVDYSQFHATFEVPTP 354
            ++VD+  F  T EV TP
Sbjct: 336 KYRVDFHNFSKTVEVETP 353


>gi|148539892 potassium inwardly-rectifying channel J1 isoform b
           [Homo sapiens]
          Length = 372

 Score =  311 bits (798), Expect = 7e-85
 Identities = 151/318 (47%), Positives = 221/318 (69%), Gaps = 5/318 (1%)

Query: 41  KKRQRFVDKNGRCNVQHGNLGSETSRYLS--DLFTTLVDLKWRWNLFIFILTYTVAWLFM 98
           ++R R V K+GRCN++ GN+ ++ SR++   D++TT++DLKWR+ + IFI  +  +W F 
Sbjct: 18  RQRARLVSKDGRCNIEFGNVEAQ-SRFIFFVDIWTTVLDLKWRYKMTIFITAFLGSWFFF 76

Query: 99  ASMWWVIAYTRGDLNKAHVG-NYTPCVANVYNFPSAFLFFIETEATIGYGYRYITDKCPE 157
             +W+ +AY   DL + H   N+TPCV N+    SAFLF +ET+ TIGYG+R +T++C  
Sbjct: 77  GLLWYAVAYIHKDLPEFHPSANHTPCVENINGLTSAFLFSLETQVTIGYGFRCVTEQCAT 136

Query: 158 GIILFLFQSILGSIVDAFLIGCMFIKMSQPKKRAETLMFSEHAVISMRDGKLTLMFRVGN 217
            I L +FQSILG I+++F+ G +  K+S+PKKRA+T+ FS++AVIS R GKL L+ RV N
Sbjct: 137 AIFLLIFQSILGVIINSFMCGAILAKISRPKKRAKTITFSKNAVISKRGGKLCLLIRVAN 196

Query: 218 LRNSHMVSAQIRCKLLKSRQTPEGEFLPLDQLELDVGFSTGADQLFLVSPLTICHVIDAK 277
           LR S ++ + I  KLLK+  TPEGE + LDQ+ ++     G + LF +SPLTI HVID  
Sbjct: 197 LRKSLLIGSHIYGKLLKTTVTPEGETIILDQININFVVDAGNENLFFISPLTIYHVIDHN 256

Query: 278 SPFYDLSQRSMQTEQFEIVVILEGIVETTGMTCQARTSYTEDEVLWGHRFFPVIS-LEEG 336
           SPF+ ++  ++  + FE+VV L+G VE+T  TCQ RTSY  +EVLWG+RF P++S  +EG
Sbjct: 257 SPFFHMAAETLLQQDFELVVFLDGTVESTSATCQVRTSYVPEEVLWGYRFAPIVSKTKEG 316

Query: 337 FFKVDYSQFHATFEVPTP 354
            ++VD+  F  T EV TP
Sbjct: 317 KYRVDFHNFSKTVEVETP 334


>gi|24497473 potassium inwardly-rectifying channel J1 isoform b
           [Homo sapiens]
          Length = 372

 Score =  311 bits (798), Expect = 7e-85
 Identities = 151/318 (47%), Positives = 221/318 (69%), Gaps = 5/318 (1%)

Query: 41  KKRQRFVDKNGRCNVQHGNLGSETSRYLS--DLFTTLVDLKWRWNLFIFILTYTVAWLFM 98
           ++R R V K+GRCN++ GN+ ++ SR++   D++TT++DLKWR+ + IFI  +  +W F 
Sbjct: 18  RQRARLVSKDGRCNIEFGNVEAQ-SRFIFFVDIWTTVLDLKWRYKMTIFITAFLGSWFFF 76

Query: 99  ASMWWVIAYTRGDLNKAHVG-NYTPCVANVYNFPSAFLFFIETEATIGYGYRYITDKCPE 157
             +W+ +AY   DL + H   N+TPCV N+    SAFLF +ET+ TIGYG+R +T++C  
Sbjct: 77  GLLWYAVAYIHKDLPEFHPSANHTPCVENINGLTSAFLFSLETQVTIGYGFRCVTEQCAT 136

Query: 158 GIILFLFQSILGSIVDAFLIGCMFIKMSQPKKRAETLMFSEHAVISMRDGKLTLMFRVGN 217
            I L +FQSILG I+++F+ G +  K+S+PKKRA+T+ FS++AVIS R GKL L+ RV N
Sbjct: 137 AIFLLIFQSILGVIINSFMCGAILAKISRPKKRAKTITFSKNAVISKRGGKLCLLIRVAN 196

Query: 218 LRNSHMVSAQIRCKLLKSRQTPEGEFLPLDQLELDVGFSTGADQLFLVSPLTICHVIDAK 277
           LR S ++ + I  KLLK+  TPEGE + LDQ+ ++     G + LF +SPLTI HVID  
Sbjct: 197 LRKSLLIGSHIYGKLLKTTVTPEGETIILDQININFVVDAGNENLFFISPLTIYHVIDHN 256

Query: 278 SPFYDLSQRSMQTEQFEIVVILEGIVETTGMTCQARTSYTEDEVLWGHRFFPVIS-LEEG 336
           SPF+ ++  ++  + FE+VV L+G VE+T  TCQ RTSY  +EVLWG+RF P++S  +EG
Sbjct: 257 SPFFHMAAETLLQQDFELVVFLDGTVESTSATCQVRTSYVPEEVLWGYRFAPIVSKTKEG 316

Query: 337 FFKVDYSQFHATFEVPTP 354
            ++VD+  F  T EV TP
Sbjct: 317 KYRVDFHNFSKTVEVETP 334


>gi|25121966 potassium inwardly-rectifying channel, subfamily J,
           member 10 [Homo sapiens]
          Length = 379

 Score =  273 bits (697), Expect = 3e-73
 Identities = 134/318 (42%), Positives = 203/318 (63%), Gaps = 3/318 (0%)

Query: 39  PKKKRQRFVDKNGRCNVQHGNLGSETSRYLSDLFTTLVDLKWRWNLFIFILTYTVAWLFM 98
           P  +R+R + K+GR NV+  ++  +   YL DL+TT +D++WR+ L +F  T+   W   
Sbjct: 23  PGIRRRRVLTKDGRSNVRMEHIADKRFLYLKDLWTTFIDMQWRYKLLLFSATFAGTWFLF 82

Query: 99  ASMWWVIAYTRGDLNKAHV-GNYTPCVANVYNFPSAFLFFIETEATIGYGYRYITDKCPE 157
             +W+++A   GDL +     N+TPCV  V+    AFLF +E++ TIGYG+RYI+++CP 
Sbjct: 83  GVVWYLVAVAHGDLLELDPPANHTPCVVQVHTLTGAFLFSLESQTTIGYGFRYISEECPL 142

Query: 158 GIILFLFQSILGSIVDAFLIGCMFIKMSQPKKRAETLMFSEHAVISMRDGKLTLMFRVGN 217
            I+L + Q +L +I++ F+ G    K+++PKKRAET+ FS+HAV++  +GK  LM RV N
Sbjct: 143 AIVLLIAQLVLTTILEIFITGTFLAKIARPKKRAETIRFSQHAVVASHNGKPCLMIRVAN 202

Query: 218 LRNSHMVSAQIRCKLLKSRQTPEGEFLPLDQLELDVGFSTGADQLFLVSPLTICHVIDAK 277
           +R S ++  Q+  KLL++ QT EGE + L+Q+ +     T +D  FL+ PLT  HV+D  
Sbjct: 203 MRKSLLIGCQVTGKLLQTHQTKEGENIRLNQVNVTFQVDTASDSPFLILPLTFYHVVDET 262

Query: 278 SPFYDLSQRSMQTEQFEIVVILEGIVETTGMTCQARTSYTEDEVLWGHRFFPVISLE-EG 336
           SP  DL  RS + + FE+V+IL G VE+T  TCQ RTSY  +E+LWG+ F P ISL   G
Sbjct: 263 SPLKDLPLRSGEGD-FELVLILSGTVESTSATCQVRTSYLPEEILWGYEFTPAISLSASG 321

Query: 337 FFKVDYSQFHATFEVPTP 354
            +  D+S F    +V +P
Sbjct: 322 KYIADFSLFDQVVKVASP 339


>gi|8923823 potassium inwardly-rectifying channel J16 [Homo sapiens]
          Length = 418

 Score =  268 bits (686), Expect = 7e-72
 Identities = 144/385 (37%), Positives = 230/385 (59%), Gaps = 22/385 (5%)

Query: 8   FGDDYQVVTTSSSGSGLQPQGPGQDPQQQLVPKKK-RQRFVDKNGRCNVQHGNLGSETSR 66
           +G  Y ++   +       + PG  P+  +  K++ R+R + K+G CNV   ++  E   
Sbjct: 4   YGSSYHIINADA-------KYPGYPPEHIIAEKRRARRRLLHKDGSCNVYFKHIFGEWGS 56

Query: 67  YLSDLFTTLVDLKWRWNLFIFILTYTVAWLFMASMWWVIAYTRGDLNKAHVGNYTPCVAN 126
           Y+ D+FTTLVD KWR    IF L+Y ++WL   S++W+IA+  GDL   +  + TPCV N
Sbjct: 57  YVVDIFTTLVDTKWRHMFVIFSLSYILSWLIFGSVFWLIAFHHGDL--LNDPDITPCVDN 114

Query: 127 VYNFPSAFLFFIETEATIGYGYRYITDKCPEGIILFLFQSILGSIVDAFLIGCMFIKMSQ 186
           V++F  AFLF +ET+ TIGYGYR +T++C   +++ + QSIL  I++ F+IG    KM+ 
Sbjct: 115 VHSFTGAFLFSLETQTTIGYGYRCVTEECSVAVLMVILQSILSCIINTFIIGAALAKMAT 174

Query: 187 PKKRAETLMFSEHAVISMRDGKLTLMFRVGNLRNSHMVSAQIRCKLLKSRQTPEGEF-LP 245
            +KRA+T+ FS  A+I MRDGKL LM+R+G+ R +H+V   +R +LL+  +  EG   + 
Sbjct: 175 ARKRAQTIRFSYFALIGMRDGKLCLMWRIGDFRPNHVVEGTVRAQLLRYTEDSEGRMTMA 234

Query: 246 LDQLELDVGFSTGADQLFLVSPLTICHVIDAKSPFYDLSQRSMQTEQFEIVVILEGIVET 305
              L+L        DQ+ LV+P+TI H ID +SP Y L ++++  + FEI+V      ++
Sbjct: 235 FKDLKL------VNDQIILVTPVTIVHEIDHESPLYALDRKAVAKDNFEILVTFIYTGDS 288

Query: 306 TGMTCQARTSYTEDEVLWGHRFFPVISLEEGFFKVDYSQFHATFEVPTPPYSV-----KE 360
           TG + Q+R+SY   E+LWGHRF  V+ ++  ++KV+  QF  + EV  P  S      K+
Sbjct: 289 TGTSHQSRSSYVPREILWGHRFNDVLEVKRKYYKVNCLQFEGSVEVYAPFCSAKQLDWKD 348

Query: 361 QEEMLLMSSPLIAPAITNSKERHNS 385
           Q+  +  + P+     +++K R  S
Sbjct: 349 QQLHIEKAPPVRESCTSDTKARRRS 373


>gi|25777630 potassium inwardly-rectifying channel J16 [Homo
           sapiens]
          Length = 418

 Score =  268 bits (686), Expect = 7e-72
 Identities = 144/385 (37%), Positives = 230/385 (59%), Gaps = 22/385 (5%)

Query: 8   FGDDYQVVTTSSSGSGLQPQGPGQDPQQQLVPKKK-RQRFVDKNGRCNVQHGNLGSETSR 66
           +G  Y ++   +       + PG  P+  +  K++ R+R + K+G CNV   ++  E   
Sbjct: 4   YGSSYHIINADA-------KYPGYPPEHIIAEKRRARRRLLHKDGSCNVYFKHIFGEWGS 56

Query: 67  YLSDLFTTLVDLKWRWNLFIFILTYTVAWLFMASMWWVIAYTRGDLNKAHVGNYTPCVAN 126
           Y+ D+FTTLVD KWR    IF L+Y ++WL   S++W+IA+  GDL   +  + TPCV N
Sbjct: 57  YVVDIFTTLVDTKWRHMFVIFSLSYILSWLIFGSVFWLIAFHHGDL--LNDPDITPCVDN 114

Query: 127 VYNFPSAFLFFIETEATIGYGYRYITDKCPEGIILFLFQSILGSIVDAFLIGCMFIKMSQ 186
           V++F  AFLF +ET+ TIGYGYR +T++C   +++ + QSIL  I++ F+IG    KM+ 
Sbjct: 115 VHSFTGAFLFSLETQTTIGYGYRCVTEECSVAVLMVILQSILSCIINTFIIGAALAKMAT 174

Query: 187 PKKRAETLMFSEHAVISMRDGKLTLMFRVGNLRNSHMVSAQIRCKLLKSRQTPEGEF-LP 245
            +KRA+T+ FS  A+I MRDGKL LM+R+G+ R +H+V   +R +LL+  +  EG   + 
Sbjct: 175 ARKRAQTIRFSYFALIGMRDGKLCLMWRIGDFRPNHVVEGTVRAQLLRYTEDSEGRMTMA 234

Query: 246 LDQLELDVGFSTGADQLFLVSPLTICHVIDAKSPFYDLSQRSMQTEQFEIVVILEGIVET 305
              L+L        DQ+ LV+P+TI H ID +SP Y L ++++  + FEI+V      ++
Sbjct: 235 FKDLKL------VNDQIILVTPVTIVHEIDHESPLYALDRKAVAKDNFEILVTFIYTGDS 288

Query: 306 TGMTCQARTSYTEDEVLWGHRFFPVISLEEGFFKVDYSQFHATFEVPTPPYSV-----KE 360
           TG + Q+R+SY   E+LWGHRF  V+ ++  ++KV+  QF  + EV  P  S      K+
Sbjct: 289 TGTSHQSRSSYVPREILWGHRFNDVLEVKRKYYKVNCLQFEGSVEVYAPFCSAKQLDWKD 348

Query: 361 QEEMLLMSSPLIAPAITNSKERHNS 385
           Q+  +  + P+     +++K R  S
Sbjct: 349 QQLHIEKAPPVRESCTSDTKARRRS 373


>gi|25777628 potassium inwardly-rectifying channel J16 [Homo
           sapiens]
          Length = 418

 Score =  268 bits (686), Expect = 7e-72
 Identities = 144/385 (37%), Positives = 230/385 (59%), Gaps = 22/385 (5%)

Query: 8   FGDDYQVVTTSSSGSGLQPQGPGQDPQQQLVPKKK-RQRFVDKNGRCNVQHGNLGSETSR 66
           +G  Y ++   +       + PG  P+  +  K++ R+R + K+G CNV   ++  E   
Sbjct: 4   YGSSYHIINADA-------KYPGYPPEHIIAEKRRARRRLLHKDGSCNVYFKHIFGEWGS 56

Query: 67  YLSDLFTTLVDLKWRWNLFIFILTYTVAWLFMASMWWVIAYTRGDLNKAHVGNYTPCVAN 126
           Y+ D+FTTLVD KWR    IF L+Y ++WL   S++W+IA+  GDL   +  + TPCV N
Sbjct: 57  YVVDIFTTLVDTKWRHMFVIFSLSYILSWLIFGSVFWLIAFHHGDL--LNDPDITPCVDN 114

Query: 127 VYNFPSAFLFFIETEATIGYGYRYITDKCPEGIILFLFQSILGSIVDAFLIGCMFIKMSQ 186
           V++F  AFLF +ET+ TIGYGYR +T++C   +++ + QSIL  I++ F+IG    KM+ 
Sbjct: 115 VHSFTGAFLFSLETQTTIGYGYRCVTEECSVAVLMVILQSILSCIINTFIIGAALAKMAT 174

Query: 187 PKKRAETLMFSEHAVISMRDGKLTLMFRVGNLRNSHMVSAQIRCKLLKSRQTPEGEF-LP 245
            +KRA+T+ FS  A+I MRDGKL LM+R+G+ R +H+V   +R +LL+  +  EG   + 
Sbjct: 175 ARKRAQTIRFSYFALIGMRDGKLCLMWRIGDFRPNHVVEGTVRAQLLRYTEDSEGRMTMA 234

Query: 246 LDQLELDVGFSTGADQLFLVSPLTICHVIDAKSPFYDLSQRSMQTEQFEIVVILEGIVET 305
              L+L        DQ+ LV+P+TI H ID +SP Y L ++++  + FEI+V      ++
Sbjct: 235 FKDLKL------VNDQIILVTPVTIVHEIDHESPLYALDRKAVAKDNFEILVTFIYTGDS 288

Query: 306 TGMTCQARTSYTEDEVLWGHRFFPVISLEEGFFKVDYSQFHATFEVPTPPYSV-----KE 360
           TG + Q+R+SY   E+LWGHRF  V+ ++  ++KV+  QF  + EV  P  S      K+
Sbjct: 289 TGTSHQSRSSYVPREILWGHRFNDVLEVKRKYYKVNCLQFEGSVEVYAPFCSAKQLDWKD 348

Query: 361 QEEMLLMSSPLIAPAITNSKERHNS 385
           Q+  +  + P+     +++K R  S
Sbjct: 349 QQLHIEKAPPVRESCTSDTKARRRS 373


>gi|21361127 potassium inwardly-rectifying channel J15 [Homo
           sapiens]
          Length = 375

 Score =  253 bits (646), Expect = 3e-67
 Identities = 123/329 (37%), Positives = 201/329 (61%), Gaps = 2/329 (0%)

Query: 40  KKKRQRFVDKNGRCNVQHGNLGSETSRYLSDLFTTLVDLKWRWNLFIFILTYTVAWLFMA 99
           K  R R + K+G  NV+   +      YL DL+TT++D+KWR+ L +F  T+ + W    
Sbjct: 23  KANRPRVMSKSGHSNVRIDKVDGIYLLYLQDLWTTVIDMKWRYKLTLFAATFVMTWFLFG 82

Query: 100 SMWWVIAYTRGDLNKAH-VGNYTPCVANVYNFPSAFLFFIETEATIGYGYRYITDKCPEG 158
            +++ IA+  GDL     + N+TPC+  V +   AFLF +E++ TIGYG R IT++CP  
Sbjct: 83  VIYYAIAFIHGDLEPGEPISNHTPCIMKVDSLTGAFLFSLESQTTIGYGVRSITEECPHA 142

Query: 159 IILFLFQSILGSIVDAFLIGCMFIKMSQPKKRAETLMFSEHAVISMRDGKLTLMFRVGNL 218
           I L + Q ++ ++++ F+ G    K+++PKKRAET+ FS  AVI+ ++GKL L+ +V N+
Sbjct: 143 IFLLVAQLVITTLIEIFITGTFLAKIARPKKRAETIKFSHCAVITKQNGKLCLVIQVANM 202

Query: 219 RNSHMVSAQIRCKLLKSRQTPEGEFLPLDQLELDVGFSTGADQLFLVSPLTICHVIDAKS 278
           R S ++  Q+  KLL++  T EGE + L+Q  +     + ++  FL+ P+T  HV+D  S
Sbjct: 203 RKSLLIQCQLSGKLLQTHVTKEGERILLNQATVKFHVDSSSESPFLILPMTFYHVLDETS 262

Query: 279 PFYDLSQRSMQTEQFEIVVILEGIVETTGMTCQARTSYTEDEVLWGHRFFPVISL-EEGF 337
           P  DL+ ++++ ++FE+VV+L   VE+T   CQ+RTSY  +E+ WG  F PV+SL + G 
Sbjct: 263 PLRDLTPQNLKEKEFELVVLLNATVESTSAVCQSRTSYIPEEIYWGFEFVPVVSLSKNGK 322

Query: 338 FKVDYSQFHATFEVPTPPYSVKEQEEMLL 366
           +  D+SQF    + P   +   + E+  L
Sbjct: 323 YVADFSQFEQIRKSPDCTFYCADSEKQQL 351


>gi|25777640 potassium inwardly-rectifying channel J15 [Homo
           sapiens]
          Length = 375

 Score =  253 bits (646), Expect = 3e-67
 Identities = 123/329 (37%), Positives = 201/329 (61%), Gaps = 2/329 (0%)

Query: 40  KKKRQRFVDKNGRCNVQHGNLGSETSRYLSDLFTTLVDLKWRWNLFIFILTYTVAWLFMA 99
           K  R R + K+G  NV+   +      YL DL+TT++D+KWR+ L +F  T+ + W    
Sbjct: 23  KANRPRVMSKSGHSNVRIDKVDGIYLLYLQDLWTTVIDMKWRYKLTLFAATFVMTWFLFG 82

Query: 100 SMWWVIAYTRGDLNKAH-VGNYTPCVANVYNFPSAFLFFIETEATIGYGYRYITDKCPEG 158
            +++ IA+  GDL     + N+TPC+  V +   AFLF +E++ TIGYG R IT++CP  
Sbjct: 83  VIYYAIAFIHGDLEPGEPISNHTPCIMKVDSLTGAFLFSLESQTTIGYGVRSITEECPHA 142

Query: 159 IILFLFQSILGSIVDAFLIGCMFIKMSQPKKRAETLMFSEHAVISMRDGKLTLMFRVGNL 218
           I L + Q ++ ++++ F+ G    K+++PKKRAET+ FS  AVI+ ++GKL L+ +V N+
Sbjct: 143 IFLLVAQLVITTLIEIFITGTFLAKIARPKKRAETIKFSHCAVITKQNGKLCLVIQVANM 202

Query: 219 RNSHMVSAQIRCKLLKSRQTPEGEFLPLDQLELDVGFSTGADQLFLVSPLTICHVIDAKS 278
           R S ++  Q+  KLL++  T EGE + L+Q  +     + ++  FL+ P+T  HV+D  S
Sbjct: 203 RKSLLIQCQLSGKLLQTHVTKEGERILLNQATVKFHVDSSSESPFLILPMTFYHVLDETS 262

Query: 279 PFYDLSQRSMQTEQFEIVVILEGIVETTGMTCQARTSYTEDEVLWGHRFFPVISL-EEGF 337
           P  DL+ ++++ ++FE+VV+L   VE+T   CQ+RTSY  +E+ WG  F PV+SL + G 
Sbjct: 263 PLRDLTPQNLKEKEFELVVLLNATVESTSAVCQSRTSYIPEEIYWGFEFVPVVSLSKNGK 322

Query: 338 FKVDYSQFHATFEVPTPPYSVKEQEEMLL 366
           +  D+SQF    + P   +   + E+  L
Sbjct: 323 YVADFSQFEQIRKSPDCTFYCADSEKQQL 351


>gi|25777638 potassium inwardly-rectifying channel J15 [Homo
           sapiens]
          Length = 375

 Score =  253 bits (646), Expect = 3e-67
 Identities = 123/329 (37%), Positives = 201/329 (61%), Gaps = 2/329 (0%)

Query: 40  KKKRQRFVDKNGRCNVQHGNLGSETSRYLSDLFTTLVDLKWRWNLFIFILTYTVAWLFMA 99
           K  R R + K+G  NV+   +      YL DL+TT++D+KWR+ L +F  T+ + W    
Sbjct: 23  KANRPRVMSKSGHSNVRIDKVDGIYLLYLQDLWTTVIDMKWRYKLTLFAATFVMTWFLFG 82

Query: 100 SMWWVIAYTRGDLNKAH-VGNYTPCVANVYNFPSAFLFFIETEATIGYGYRYITDKCPEG 158
            +++ IA+  GDL     + N+TPC+  V +   AFLF +E++ TIGYG R IT++CP  
Sbjct: 83  VIYYAIAFIHGDLEPGEPISNHTPCIMKVDSLTGAFLFSLESQTTIGYGVRSITEECPHA 142

Query: 159 IILFLFQSILGSIVDAFLIGCMFIKMSQPKKRAETLMFSEHAVISMRDGKLTLMFRVGNL 218
           I L + Q ++ ++++ F+ G    K+++PKKRAET+ FS  AVI+ ++GKL L+ +V N+
Sbjct: 143 IFLLVAQLVITTLIEIFITGTFLAKIARPKKRAETIKFSHCAVITKQNGKLCLVIQVANM 202

Query: 219 RNSHMVSAQIRCKLLKSRQTPEGEFLPLDQLELDVGFSTGADQLFLVSPLTICHVIDAKS 278
           R S ++  Q+  KLL++  T EGE + L+Q  +     + ++  FL+ P+T  HV+D  S
Sbjct: 203 RKSLLIQCQLSGKLLQTHVTKEGERILLNQATVKFHVDSSSESPFLILPMTFYHVLDETS 262

Query: 279 PFYDLSQRSMQTEQFEIVVILEGIVETTGMTCQARTSYTEDEVLWGHRFFPVISL-EEGF 337
           P  DL+ ++++ ++FE+VV+L   VE+T   CQ+RTSY  +E+ WG  F PV+SL + G 
Sbjct: 263 PLRDLTPQNLKEKEFELVVLLNATVESTSAVCQSRTSYIPEEIYWGFEFVPVVSLSKNGK 322

Query: 338 FKVDYSQFHATFEVPTPPYSVKEQEEMLL 366
           +  D+SQF    + P   +   + E+  L
Sbjct: 323 YVADFSQFEQIRKSPDCTFYCADSEKQQL 351


>gi|156119627 potassium inwardly-rectifying channel J13 [Homo
           sapiens]
          Length = 360

 Score =  179 bits (453), Expect = 7e-45
 Identities = 105/319 (32%), Positives = 168/319 (52%), Gaps = 10/319 (3%)

Query: 41  KKRQRFVDKNGRCNVQHGNLGSETSRYLSDLFTTLVDLKWRWNLFIFILTYTVAWLFMAS 100
           ++ +R V K+G   +Q          YL D +  L+D++WRW + +F  ++ V WL  A 
Sbjct: 15  QRYRRMVTKDGHSTLQMDG-AQRGLAYLRDAWGILMDMRWRWMMLVFSASFVVHWLVFAV 73

Query: 101 MWWVIAYTRGDLNKAHVG---NYTPCVANVYNFPSAFLFFIETEATIGYGYRYITDKCPE 157
           +W+V+A   GDL   H     N+T CV  + +F +AF F +ET+ TIGYG  + +  CP 
Sbjct: 74  LWYVLAEMNGDLELDHDAPPENHTICVKYITSFTAAFSFSLETQLTIGYGTMFPSGDCPS 133

Query: 158 GIILFLFQSILGSIVDAFLIGCMFIKMSQPKKRAETLMFSEHAVISMRDGKLTLMFRVGN 217
            I L   Q +LG +++AF+ G    K+++PK RA ++ F++ AV++  DGK  L+F+V N
Sbjct: 134 AIALLAIQMLLGLMLEAFITGAFVAKIARPKNRAFSIRFTDTAVVAHMDGKPNLIFQVAN 193

Query: 218 LRNSHMVSAQIRCKLLKSRQTPEGEFLPLDQLELDVGFSTGADQLFLVSPLTICHVIDAK 277
            R S + S ++   L + R+  +   L    ++  +   +  +  F + PLT  H I   
Sbjct: 194 TRPSPLTSVRVSAVLYQERENGK---LYQTSVDFHLDGISSDECPFFIFPLTYYHSITPS 250

Query: 278 SPFYDLSQRSMQTEQFEIVVILEGIVETTGMTCQARTSYTEDEVLWGHRFFPVISL-EEG 336
           SP   L Q       FE+VV L  + E TG  CQ RTSY   E++  H F  +++   +G
Sbjct: 251 SPLATLLQHE-NPSHFELVVFLSAMQEGTGEICQRRTSYLPSEIMLHHCFASLLTRGSKG 309

Query: 337 FFKVDYSQFHATF-EVPTP 354
            +++    F  T  E PTP
Sbjct: 310 EYQIKMENFDKTVPEFPTP 328


>gi|148806865 zinc finger protein 492 [Homo sapiens]
          Length = 531

 Score = 33.5 bits (75), Expect = 0.46
 Identities = 35/175 (20%), Positives = 63/175 (36%), Gaps = 9/175 (5%)

Query: 311 QARTSYTEDEVLWGHRFFPVISLEEGFFKVDYSQFHATFEVPTPPYSVKEQEEMLLMSSP 370
           Q+ T  T   +  G +F+      + F +  +   H        PY  +E  +   +SS 
Sbjct: 348 QSSTLTTHKRIHAGEKFYKCEVCSKAFSRFSHLTTHKRIHTGEKPYKCEECGKAFNLSSQ 407

Query: 371 LIAPAITNSKER-HNSVECLDGLDDITTKLPSKL----QKITGREDFPKKLLRMSSTTSE 425
           L    I ++ E+ +   EC    +  +T    K+    +K    E+  K   + S  T+ 
Sbjct: 408 LTTHKIIHTGEKPYKCEECGKAFNQSSTLSKHKVIHTGEKPYKYEECGKAFNQSSHLTTH 467

Query: 426 KAYSLGDLPMKLQRISSVPGNS----EEKLVSKTTKMLSDPMSQSVADLPPKLQK 476
           K    G+ P K +       NS      K++    K+       +  D   K+ K
Sbjct: 468 KMIHTGEKPYKCEECGKAFNNSSILNRHKMIHTGEKLYKPESCNNACDNIAKISK 522


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.320    0.135    0.400 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 18,582,333
Number of Sequences: 37866
Number of extensions: 810029
Number of successful extensions: 2231
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 39
Number of HSP's successfully gapped in prelim test: 15
Number of HSP's that attempted gapping in prelim test: 2133
Number of HSP's gapped (non-prelim): 68
length of query: 501
length of database: 18,247,518
effective HSP length: 106
effective length of query: 395
effective length of database: 14,233,722
effective search space: 5622320190
effective search space used: 5622320190
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 64 (29.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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