Search of human proteins with 4504509

Search of human proteins with 4504509

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|4504509 3 beta-hydroxysteroid dehydrogenase 2 [Homo sapiens]
         (372 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|4504509 3 beta-hydroxysteroid dehydrogenase 2 [Homo sapiens]       754   0.0  
gi|4504507 3 beta-hydroxysteroid dehydrogenase 1 [Homo sapiens]       714   0.0  
gi|19923621 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and s...   241   1e-63
gi|116268111 short chain dehydrogenase/reductase family 42E, mem...   128   7e-30
gi|218563686 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and ...   119   6e-27
gi|218563684 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and ...   119   6e-27
gi|193211614 NAD(P) dependent steroid dehydrogenase-like [Homo s...   113   2e-25
gi|8393516 NAD(P) dependent steroid dehydrogenase-like [Homo sap...   113   2e-25
gi|239745448 PREDICTED: hypothetical protein XP_002343493 [Homo ...   112   4e-25
gi|239756515 PREDICTED: similar to Putative 3-beta-HSD family pr...   110   2e-24
gi|239751020 PREDICTED: hypothetical protein XP_002347673 [Homo ...   110   2e-24
gi|7657641 TDP-glucose 4,6-dehydratase [Homo sapiens]                  59   5e-09
gi|56118217 UDP-galactose-4-epimerase [Homo sapiens]                   40   0.003
gi|56237023 UDP-galactose-4-epimerase [Homo sapiens]                   40   0.003
gi|189083684 UDP-galactose-4-epimerase [Homo sapiens]                  40   0.003
gi|31542658 fatty acyl CoA reductase 2 [Homo sapiens]                  32   0.70 
gi|150456451 hypothetical protein LOC54914 [Homo sapiens]              29   7.8  

>gi|4504509 3 beta-hydroxysteroid dehydrogenase 2 [Homo sapiens]
          Length = 372

 Score =  754 bits (1947), Expect = 0.0
 Identities = 372/372 (100%), Positives = 372/372 (100%)

Query: 1   MGWSCLVTGAGGLLGQRIVRLLVEEKELKEIRALDKAFRPELREEFSKLQNRTKLTVLEG 60
           MGWSCLVTGAGGLLGQRIVRLLVEEKELKEIRALDKAFRPELREEFSKLQNRTKLTVLEG
Sbjct: 1   MGWSCLVTGAGGLLGQRIVRLLVEEKELKEIRALDKAFRPELREEFSKLQNRTKLTVLEG 60

Query: 61  DILDEPFLKRACQDVSVVIHTACIIDVFGVTHRESIMNVNVKGTQLLLEACVQASVPVFI 120
           DILDEPFLKRACQDVSVVIHTACIIDVFGVTHRESIMNVNVKGTQLLLEACVQASVPVFI
Sbjct: 61  DILDEPFLKRACQDVSVVIHTACIIDVFGVTHRESIMNVNVKGTQLLLEACVQASVPVFI 120

Query: 121 YTSSIEVAGPNSYKEIIQNGHEEEPLENTWPTPYPYSKKLAEKAVLAANGWNLKNGDTLY 180
           YTSSIEVAGPNSYKEIIQNGHEEEPLENTWPTPYPYSKKLAEKAVLAANGWNLKNGDTLY
Sbjct: 121 YTSSIEVAGPNSYKEIIQNGHEEEPLENTWPTPYPYSKKLAEKAVLAANGWNLKNGDTLY 180

Query: 181 TCALRPTYIYGEGGPFLSASINEALNNNGILSSVGKFSTVNPVYVGNVAWAHILALRALR 240
           TCALRPTYIYGEGGPFLSASINEALNNNGILSSVGKFSTVNPVYVGNVAWAHILALRALR
Sbjct: 181 TCALRPTYIYGEGGPFLSASINEALNNNGILSSVGKFSTVNPVYVGNVAWAHILALRALR 240

Query: 241 DPKKAPSVRGQFYYISDDTPHQSYDNLNYILSKEFGLRLDSRWSLPLTLMYWIGFLLEVV 300
           DPKKAPSVRGQFYYISDDTPHQSYDNLNYILSKEFGLRLDSRWSLPLTLMYWIGFLLEVV
Sbjct: 241 DPKKAPSVRGQFYYISDDTPHQSYDNLNYILSKEFGLRLDSRWSLPLTLMYWIGFLLEVV 300

Query: 301 SFLLSPIYSYQPPFNRHTVTLSNSVFTFSYKKAQRDLAYKPLYSWEEAKQKTVEWVGSLV 360
           SFLLSPIYSYQPPFNRHTVTLSNSVFTFSYKKAQRDLAYKPLYSWEEAKQKTVEWVGSLV
Sbjct: 301 SFLLSPIYSYQPPFNRHTVTLSNSVFTFSYKKAQRDLAYKPLYSWEEAKQKTVEWVGSLV 360

Query: 361 DRHKETLKSKTQ 372
           DRHKETLKSKTQ
Sbjct: 361 DRHKETLKSKTQ 372


>gi|4504507 3 beta-hydroxysteroid dehydrogenase 1 [Homo sapiens]
          Length = 373

 Score =  714 bits (1843), Expect = 0.0
 Identities = 348/371 (93%), Positives = 359/371 (96%)

Query: 2   GWSCLVTGAGGLLGQRIVRLLVEEKELKEIRALDKAFRPELREEFSKLQNRTKLTVLEGD 61
           GWSCLVTGAGG LGQRI+RLLV+EKELKEIR LDKAF PELREEFSKLQN+TKLTVLEGD
Sbjct: 3   GWSCLVTGAGGFLGQRIIRLLVKEKELKEIRVLDKAFGPELREEFSKLQNKTKLTVLEGD 62

Query: 62  ILDEPFLKRACQDVSVVIHTACIIDVFGVTHRESIMNVNVKGTQLLLEACVQASVPVFIY 121
           ILDEPFLKRACQDVSV+IHTACIIDVFGVTHRESIMNVNVKGTQLLLEACVQASVPVFIY
Sbjct: 63  ILDEPFLKRACQDVSVIIHTACIIDVFGVTHRESIMNVNVKGTQLLLEACVQASVPVFIY 122

Query: 122 TSSIEVAGPNSYKEIIQNGHEEEPLENTWPTPYPYSKKLAEKAVLAANGWNLKNGDTLYT 181
           TSSIEVAGPNSYKEIIQNGHEEEPLENTWP PYP+SKKLAEKAVLAANGWNLKNG TLYT
Sbjct: 123 TSSIEVAGPNSYKEIIQNGHEEEPLENTWPAPYPHSKKLAEKAVLAANGWNLKNGGTLYT 182

Query: 182 CALRPTYIYGEGGPFLSASINEALNNNGILSSVGKFSTVNPVYVGNVAWAHILALRALRD 241
           CALRP YIYGEG  FLSASINEALNNNGILSSVGKFSTVNPVYVGNVAWAHILALRAL+D
Sbjct: 183 CALRPMYIYGEGSRFLSASINEALNNNGILSSVGKFSTVNPVYVGNVAWAHILALRALQD 242

Query: 242 PKKAPSVRGQFYYISDDTPHQSYDNLNYILSKEFGLRLDSRWSLPLTLMYWIGFLLEVVS 301
           PKKAPS+RGQFYYISDDTPHQSYDNLNY LSKEFGLRLDSRWS PL+LMYWIGFLLE+VS
Sbjct: 243 PKKAPSIRGQFYYISDDTPHQSYDNLNYTLSKEFGLRLDSRWSFPLSLMYWIGFLLEIVS 302

Query: 302 FLLSPIYSYQPPFNRHTVTLSNSVFTFSYKKAQRDLAYKPLYSWEEAKQKTVEWVGSLVD 361
           FLL PIY+Y+PPFNRH VTLSNSVFTFSYKKAQRDLAYKPLYSWEEAKQKTVEWVGSLVD
Sbjct: 303 FLLRPIYTYRPPFNRHIVTLSNSVFTFSYKKAQRDLAYKPLYSWEEAKQKTVEWVGSLVD 362

Query: 362 RHKETLKSKTQ 372
           RHKETLKSKTQ
Sbjct: 363 RHKETLKSKTQ 373


>gi|19923621 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and
           steroid delta-isomerase 7 isoform a [Homo sapiens]
          Length = 369

 Score =  241 bits (614), Expect = 1e-63
 Identities = 140/354 (39%), Positives = 204/354 (57%), Gaps = 8/354 (2%)

Query: 6   LVTGAGGLLGQRIVRLLVE-EKELKEIRALDKAFRPELREEFSKLQNRTKLTVLEGDILD 64
           LVTG  G LG+ +VR+L++ E  L E+R  D+   P L E  +      ++T ++GD+  
Sbjct: 13  LVTGGCGFLGEHVVRMLLQREPRLGELRVFDQHLGPWLEELKT---GPVRVTAIQGDVTQ 69

Query: 65  EPFLKRACQDVSVVIHTACIIDVFGVTHRESIMNVNVKGTQLLLEACVQASVPVFIYTSS 124
              +  A     VVIHTA ++DVFG    ++I  VNV+GT+ ++EACVQ      +YTSS
Sbjct: 70  AHEVAAAVAGAHVVIHTAGLVDVFGRASPKTIHEVNVQGTRNVIEACVQTGTRFLVYTSS 129

Query: 125 IEVAGPNSYKEIIQNGHEEEPLENTWPTPYPYSKKLAEKAVLAANGWNLKNGDTLYTCAL 184
           +EV GPN+       G+E+ P E     PYP SK LAE  VL ANG  ++ G  L TCAL
Sbjct: 130 MEVVGPNTKGHPFYRGNEDTPYEAVHRHPYPCSKALAEWLVLEANGRKVRGGLPLVTCAL 189

Query: 185 RPTYIYGEGGPFLSASINEALNNNG-ILSSVGKFSTVNPVYVGNVAWAHILALRALRDPK 243
           RPT IYGEG   +     + L   G +  ++        VYVGNVAW H+LA R L   +
Sbjct: 190 RPTGIYGEGHQIMRDFYRQGLRLGGWLFRAIPASVEHGRVYVGNVAWMHVLAARELE--Q 247

Query: 244 KAPSVRGQFYYISDDTPHQSYDNLNYILSKEFGLRL-DSRWSLPLTLMYWIGFLLEVVSF 302
           +A  + GQ Y+  D +P++SY++ N       GLRL  +R  LP  L+ ++  L  ++ +
Sbjct: 248 RATLMGGQVYFCYDGSPYRSYEDFNMEFLGPCGLRLVGARPLLPYWLLVFLAALNALLQW 307

Query: 303 LLSPIYSYQPPFNRHTVTLSNSVFTFSYKKAQRDLAYKPLYSWEEAKQKTVEWV 356
           LL P+  Y P  N +T+ ++N+ FT S  KAQR   Y+PL+SWE+++ +T+ WV
Sbjct: 308 LLRPLVLYAPLLNPYTLAVANTTFTVSTDKAQRHFGYEPLFSWEDSRTRTILWV 361


>gi|116268111 short chain dehydrogenase/reductase family 42E, member
           1 [Homo sapiens]
          Length = 393

 Score =  128 bits (322), Expect = 7e-30
 Identities = 107/310 (34%), Positives = 154/310 (49%), Gaps = 26/310 (8%)

Query: 58  LEGDILDEPFLKRACQDVSVVIHTACIIDV--FGVTHRES-----IMNVNVKGTQLLLEA 110
           ++GDI     +++A QD  V     C+  +  +G++ RE      I  VNV+GT  +L+ 
Sbjct: 54  IQGDIRHLSDVEKAFQDADVT----CVFHIASYGMSGREQLNRNLIKEVNVRGTDNILQV 109

Query: 111 CVQASVPVFIYTSSIEVAGPNSYKEIIQNGHEEEPLE--NTWPTPYPYSKKLAEKAVLAA 168
           C +  VP  +YTS+  V       ++I+NG E  P    +  P  Y  +K +AE+ VL A
Sbjct: 110 CQRRRVPRLVYTSTFNVIFGG---QVIRNGDESLPYLPLHLHPDHYSRTKSIAEQKVLEA 166

Query: 169 NGWNLKNGD-TLYTCALRPTYIYGEGGPFLSASINEALNNNGILSSV--GKFSTVNPVYV 225
           N   L  GD  L TCALRP  IYG G       I   +   G+   V     S V  V+V
Sbjct: 167 NATPLDRGDGVLRTCALRPAGIYGPGEQRHLPRIVSYIEK-GLFKFVYGDPRSLVEFVHV 225

Query: 226 GNVAWAHILALRALRDPKKAPSVRGQFYYISDDTPHQSYDNLNYILSKEFGLRLDSRWSL 285
            N+  AHILA  ALR   K     GQ Y+ISD  P  +++    ++ +  G    S   L
Sbjct: 226 DNLVQAHILASEALR-ADKGHIASGQPYFISDGRPVNNFEFFRPLV-EGLGYTFPST-RL 282

Query: 286 PLTLMYWIGFLLEVVSFLLSPIYSYQPPFNRHTVTLSNSVFTFSYKKAQRDLAYKPLYSW 345
           PLTL+Y   FL E+V F+L  +Y++QP   R  V  +     FS +KA+++L YK   + 
Sbjct: 283 PLTLVYCFAFLTEMVHFILGRLYNFQPFLTRTEVYKTGVTHYFSLEKAKKELGYK---AQ 339

Query: 346 EEAKQKTVEW 355
               Q+ VEW
Sbjct: 340 PFDLQEAVEW 349


>gi|218563686 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and
           steroid delta-isomerase 7 isoform b [Homo sapiens]
          Length = 196

 Score =  119 bits (297), Expect = 6e-27
 Identities = 69/166 (41%), Positives = 96/166 (57%), Gaps = 4/166 (2%)

Query: 6   LVTGAGGLLGQRIVRLLVE-EKELKEIRALDKAFRPELREEFSKLQNRTKLTVLEGDILD 64
           LVTG  G LG+ +VR+L++ E  L E+R  D+   P L E  +      ++T ++GD+  
Sbjct: 13  LVTGGCGFLGEHVVRMLLQREPRLGELRVFDQHLGPWLEELKT---GPVRVTAIQGDVTQ 69

Query: 65  EPFLKRACQDVSVVIHTACIIDVFGVTHRESIMNVNVKGTQLLLEACVQASVPVFIYTSS 124
              +  A     VVIHTA ++DVFG    ++I  VNV+GT+ ++EACVQ      +YTSS
Sbjct: 70  AHEVAAAVAGAHVVIHTAGLVDVFGRASPKTIHEVNVQGTRNVIEACVQTGTRFLVYTSS 129

Query: 125 IEVAGPNSYKEIIQNGHEEEPLENTWPTPYPYSKKLAEKAVLAANG 170
           +EV GPN+       G+E+ P E     PYP SK LAE  VL ANG
Sbjct: 130 MEVVGPNTKGHPFYRGNEDTPYEAVHRHPYPCSKALAEWLVLEANG 175


>gi|218563684 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and
           steroid delta-isomerase 7 isoform b [Homo sapiens]
          Length = 196

 Score =  119 bits (297), Expect = 6e-27
 Identities = 69/166 (41%), Positives = 96/166 (57%), Gaps = 4/166 (2%)

Query: 6   LVTGAGGLLGQRIVRLLVE-EKELKEIRALDKAFRPELREEFSKLQNRTKLTVLEGDILD 64
           LVTG  G LG+ +VR+L++ E  L E+R  D+   P L E  +      ++T ++GD+  
Sbjct: 13  LVTGGCGFLGEHVVRMLLQREPRLGELRVFDQHLGPWLEELKT---GPVRVTAIQGDVTQ 69

Query: 65  EPFLKRACQDVSVVIHTACIIDVFGVTHRESIMNVNVKGTQLLLEACVQASVPVFIYTSS 124
              +  A     VVIHTA ++DVFG    ++I  VNV+GT+ ++EACVQ      +YTSS
Sbjct: 70  AHEVAAAVAGAHVVIHTAGLVDVFGRASPKTIHEVNVQGTRNVIEACVQTGTRFLVYTSS 129

Query: 125 IEVAGPNSYKEIIQNGHEEEPLENTWPTPYPYSKKLAEKAVLAANG 170
           +EV GPN+       G+E+ P E     PYP SK LAE  VL ANG
Sbjct: 130 MEVVGPNTKGHPFYRGNEDTPYEAVHRHPYPCSKALAEWLVLEANG 175


>gi|193211614 NAD(P) dependent steroid dehydrogenase-like [Homo
           sapiens]
          Length = 373

 Score =  113 bits (283), Expect = 2e-25
 Identities = 99/354 (27%), Positives = 168/354 (47%), Gaps = 33/354 (9%)

Query: 5   CLVTGAGGLLGQRIVRLLVEEKELKEIRALDKAF-RPELREEFSKLQNRTKLTVLEGDIL 63
           C V G  G LGQ +V  L+       +  + + F  P++R                GD+ 
Sbjct: 40  CTVIGGSGFLGQHMVEQLLARGYAVNVFDIQQGFDNPQVR-------------FFLGDLC 86

Query: 64  DEPFLKRACQDVSVVIHTACIIDVFGVTHRESIMNVNVKGTQLLLEACVQASVPVFIYTS 123
               L  A + V+ V H  C        ++E    VN  GT+ ++E C +A V   I TS
Sbjct: 87  SRQDLYPALKGVNTVFH--CASPPPSSNNKELFYRVNYIGTKNVIETCKEAGVQKLILTS 144

Query: 124 SIEVAGPNSYKEI-IQNGHEEEPLENTWPTPYPYSKKLAEKAVLAANGWNLKNGDTLYTC 182
           S  V     ++ + I+NG E+ P        Y  +K L E+AVL AN    KN     T 
Sbjct: 145 SASVI----FEGVDIKNGTEDLPYAMKPIDYYTETKILQERAVLGANDPE-KN---FLTT 196

Query: 183 ALRPTYIYGEGGPFLSASINEALNNNGILSSVGKFST-VNPVYVGNVAWAHILALRALRD 241
           A+RP  I+G   P L   + EA  N  +   +G     V+  +V NV   HILA   L  
Sbjct: 197 AIRPHGIFGPRDPQLVPILIEAARNGKMKFVIGNGKNLVDFTFVENVVHGHILAAEQL-- 254

Query: 242 PKKAPSVRGQFYYISDDTPHQSYDNLNYILSKEFGLRLDS-RWSLPLTLMYWIGFLLEVV 300
             +  ++ G+ ++I++D P   +  L+ IL+   GL  ++ ++ +P  + Y++  LL ++
Sbjct: 255 -SRDSTLGGKAFHITNDEPIPFWTFLSRILT---GLNYEAPKYHIPYWVAYYLALLLSLL 310

Query: 301 SFLLSPIYSYQPPFNRHTVTLSNSVFTFSYKKAQRDLAYKPLYSWEEAKQKTVE 354
             ++SP+   QP F    V L+ +   +S ++A++ + Y+PL + ++A ++TV+
Sbjct: 311 VMVISPVIQLQPTFTPMRVALAGTFHYYSCERAKKAMGYQPLVTMDDAMERTVQ 364


>gi|8393516 NAD(P) dependent steroid dehydrogenase-like [Homo
           sapiens]
          Length = 373

 Score =  113 bits (283), Expect = 2e-25
 Identities = 99/354 (27%), Positives = 168/354 (47%), Gaps = 33/354 (9%)

Query: 5   CLVTGAGGLLGQRIVRLLVEEKELKEIRALDKAF-RPELREEFSKLQNRTKLTVLEGDIL 63
           C V G  G LGQ +V  L+       +  + + F  P++R                GD+ 
Sbjct: 40  CTVIGGSGFLGQHMVEQLLARGYAVNVFDIQQGFDNPQVR-------------FFLGDLC 86

Query: 64  DEPFLKRACQDVSVVIHTACIIDVFGVTHRESIMNVNVKGTQLLLEACVQASVPVFIYTS 123
               L  A + V+ V H  C        ++E    VN  GT+ ++E C +A V   I TS
Sbjct: 87  SRQDLYPALKGVNTVFH--CASPPPSSNNKELFYRVNYIGTKNVIETCKEAGVQKLILTS 144

Query: 124 SIEVAGPNSYKEI-IQNGHEEEPLENTWPTPYPYSKKLAEKAVLAANGWNLKNGDTLYTC 182
           S  V     ++ + I+NG E+ P        Y  +K L E+AVL AN    KN     T 
Sbjct: 145 SASVI----FEGVDIKNGTEDLPYAMKPIDYYTETKILQERAVLGANDPE-KN---FLTT 196

Query: 183 ALRPTYIYGEGGPFLSASINEALNNNGILSSVGKFST-VNPVYVGNVAWAHILALRALRD 241
           A+RP  I+G   P L   + EA  N  +   +G     V+  +V NV   HILA   L  
Sbjct: 197 AIRPHGIFGPRDPQLVPILIEAARNGKMKFVIGNGKNLVDFTFVENVVHGHILAAEQL-- 254

Query: 242 PKKAPSVRGQFYYISDDTPHQSYDNLNYILSKEFGLRLDS-RWSLPLTLMYWIGFLLEVV 300
             +  ++ G+ ++I++D P   +  L+ IL+   GL  ++ ++ +P  + Y++  LL ++
Sbjct: 255 -SRDSTLGGKAFHITNDEPIPFWTFLSRILT---GLNYEAPKYHIPYWVAYYLALLLSLL 310

Query: 301 SFLLSPIYSYQPPFNRHTVTLSNSVFTFSYKKAQRDLAYKPLYSWEEAKQKTVE 354
             ++SP+   QP F    V L+ +   +S ++A++ + Y+PL + ++A ++TV+
Sbjct: 311 VMVISPVIQLQPTFTPMRVALAGTFHYYSCERAKKAMGYQPLVTMDDAMERTVQ 364


>gi|239745448 PREDICTED: hypothetical protein XP_002343493 [Homo
           sapiens]
          Length = 422

 Score =  112 bits (281), Expect = 4e-25
 Identities = 107/347 (30%), Positives = 157/347 (45%), Gaps = 33/347 (9%)

Query: 6   LVTGAGGLLGQRIVRLLVEEKELKEIRALDKAFRPELREEFSKLQNRTKLTVLEGDILDE 65
           LVTG GG LG  +   L   K    +  LD+  RP+      +L   TK   ++ D+ DE
Sbjct: 37  LVTGGGGYLGFSLGSHLA--KSGTSVILLDRR-RPQW-----ELSPETKF--IQADVRDE 86

Query: 66  PFLKRACQDVSVVIHTACIIDVFGVT-----HRESIMNVNVKGTQLLLEACVQASVPVFI 120
             L RA + V  V H A     +G++      +E I ++NV GT+L+++ CV+  VP  I
Sbjct: 87  EALYRAFEGVDCVFHVAS----YGMSGAEKLQKEQIESINVGGTKLVIDVCVRRRVPRLI 142

Query: 121 YTSSIEVAGPNSYKEIIQNGHEEE----PLENTWPTPYPYSKKLAEKAVLAANGWNLKNG 176
           YTS++ VA      + I+ G E+     PL+      Y  +K +A++  L ANG  L  G
Sbjct: 143 YTSTVNVAFGG---KPIEQGDEDSVPYFPLDE-HVDHYSRTKAIADQLTLMANGMPLPGG 198

Query: 177 DTLYTCALRPTYIYGEGGPFLSASINEALNNNGILSSVGKF-STVNPVYVGNVAWAHILA 235
            TL TC LRP  IYG         +   +     +   G   + +N V+V N+  AH+LA
Sbjct: 199 GTLRTCVLRPPGIYGPEEQRHLPRVAGHIKKRLFMFRFGDHKARMNWVHVHNLVQAHVLA 258

Query: 236 LRALRDPKKAPSVRGQFYYISDDTPHQSYDNLNYILSKEFGLRLDSRW-SLPLTLMYWIG 294
             AL    K     GQ YYI+D      ++ +  +  K   L     W  +P + +Y   
Sbjct: 259 AEAL-TTAKGYVASGQAYYINDGESVNLFEWMAPLFEK---LGYSQPWIQVPTSWVYLTA 314

Query: 295 FLLEVVSFLLSPIYSYQPPFNRHTVTLSNSVFTFSYKKAQRDLAYKP 341
            ++E +   L PI S  P   R  V       TF   KA+  L Y P
Sbjct: 315 AVMERLHLALRPICSLPPLLTRSEVRSVAVTHTFQIAKARAQLGYAP 361


>gi|239756515 PREDICTED: similar to Putative 3-beta-HSD family
           protein ENSP00000330812 [Homo sapiens]
          Length = 422

 Score =  110 bits (276), Expect = 2e-24
 Identities = 106/347 (30%), Positives = 156/347 (44%), Gaps = 33/347 (9%)

Query: 6   LVTGAGGLLGQRIVRLLVEEKELKEIRALDKAFRPELREEFSKLQNRTKLTVLEGDILDE 65
           LVTG GG LG  +   L   K    +  LD+  RP+      +L   TK   ++ D+ DE
Sbjct: 37  LVTGGGGYLGFSLGSHLA--KSGTSVILLDRR-RPQW-----ELSPETKF--IQADVRDE 86

Query: 66  PFLKRACQDVSVVIHTACIIDVFGVT-----HRESIMNVNVKGTQLLLEACVQASVPVFI 120
             L  A + V  V H A     +G++      +E I ++NV GT+L+++ CV+  VP  I
Sbjct: 87  EALYHAFEGVDCVFHVAS----YGMSGAEKLQKEQIESINVGGTKLVIDVCVRRRVPRLI 142

Query: 121 YTSSIEVAGPNSYKEIIQNGHEEE----PLENTWPTPYPYSKKLAEKAVLAANGWNLKNG 176
           YTS++ VA      + I+ G E+     PL+      Y  +K +A++  L ANG  L  G
Sbjct: 143 YTSTVNVAFGG---KPIEQGDEDSVPYFPLDE-HVDHYSRTKAIADQLTLMANGMPLPGG 198

Query: 177 DTLYTCALRPTYIYGEGGPFLSASINEALNNNGILSSVGKF-STVNPVYVGNVAWAHILA 235
            TL TC LRP  IYG         +   +     +   G   + +N V+V N+  AH+LA
Sbjct: 199 GTLRTCVLRPPGIYGPEEQRHLPRVAGHIKKRLFMFRFGDHKARMNWVHVHNLVQAHVLA 258

Query: 236 LRALRDPKKAPSVRGQFYYISDDTPHQSYDNLNYILSKEFGLRLDSRW-SLPLTLMYWIG 294
             AL    K     GQ YYI+D      ++ +  +  K   L     W  +P + +Y   
Sbjct: 259 AEAL-TTAKGYVASGQAYYINDGESVNLFEWMAPLFEK---LGYSQPWIQVPTSWVYLTA 314

Query: 295 FLLEVVSFLLSPIYSYQPPFNRHTVTLSNSVFTFSYKKAQRDLAYKP 341
            ++E +   L PI S  P   R  V       TF   KA+  L Y P
Sbjct: 315 AVMERLHLALRPICSLPPLLTRSEVRSVAVTHTFQIAKARAQLGYAP 361


>gi|239751020 PREDICTED: hypothetical protein XP_002347673 [Homo
           sapiens]
          Length = 422

 Score =  110 bits (276), Expect = 2e-24
 Identities = 106/347 (30%), Positives = 156/347 (44%), Gaps = 33/347 (9%)

Query: 6   LVTGAGGLLGQRIVRLLVEEKELKEIRALDKAFRPELREEFSKLQNRTKLTVLEGDILDE 65
           LVTG GG LG  +   L   K    +  LD+  RP+      +L   TK   ++ D+ DE
Sbjct: 37  LVTGGGGYLGFSLGSHLA--KSGTSVILLDRR-RPQW-----ELSPETKF--IQADVRDE 86

Query: 66  PFLKRACQDVSVVIHTACIIDVFGVT-----HRESIMNVNVKGTQLLLEACVQASVPVFI 120
             L  A + V  V H A     +G++      +E I ++NV GT+L+++ CV+  VP  I
Sbjct: 87  EALYHAFEGVDCVFHVAS----YGMSGAEKLQKEQIESINVGGTKLVIDVCVRRRVPRLI 142

Query: 121 YTSSIEVAGPNSYKEIIQNGHEEE----PLENTWPTPYPYSKKLAEKAVLAANGWNLKNG 176
           YTS++ VA      + I+ G E+     PL+      Y  +K +A++  L ANG  L  G
Sbjct: 143 YTSTVNVAFGG---KPIEQGDEDSVPYFPLDE-HVDHYSRTKAIADQLTLMANGMPLPGG 198

Query: 177 DTLYTCALRPTYIYGEGGPFLSASINEALNNNGILSSVGKF-STVNPVYVGNVAWAHILA 235
            TL TC LRP  IYG         +   +     +   G   + +N V+V N+  AH+LA
Sbjct: 199 GTLRTCVLRPPGIYGPEEQRHLPRVAGHIKKRLFMFRFGDHKARMNWVHVHNLVQAHVLA 258

Query: 236 LRALRDPKKAPSVRGQFYYISDDTPHQSYDNLNYILSKEFGLRLDSRW-SLPLTLMYWIG 294
             AL    K     GQ YYI+D      ++ +  +  K   L     W  +P + +Y   
Sbjct: 259 AEAL-TTAKGYVASGQAYYINDGESVNLFEWMAPLFEK---LGYSQPWIQVPTSWVYLTA 314

Query: 295 FLLEVVSFLLSPIYSYQPPFNRHTVTLSNSVFTFSYKKAQRDLAYKP 341
            ++E +   L PI S  P   R  V       TF   KA+  L Y P
Sbjct: 315 AVMERLHLALRPICSLPPLLTRSEVRSVAVTHTFQIAKARAQLGYAP 361


>gi|7657641 TDP-glucose 4,6-dehydratase [Homo sapiens]
          Length = 350

 Score = 59.3 bits (142), Expect = 5e-09
 Identities = 50/160 (31%), Positives = 70/160 (43%), Gaps = 9/160 (5%)

Query: 6   LVTGAGGLLGQRIVRLLVEEKELKEIRALDKAFRPELREEFSKLQNRTKLTVLEGDILDE 65
           LVTG  G +   ++  LVE+     I  LDK       +    + N+     ++GDI D 
Sbjct: 21  LVTGGAGFIASHMIVSLVEDYPNYMIINLDKLDYCASLKNLETISNKQNYKFIQGDICDS 80

Query: 66  PFLKRA--CQDVSVVIHTACIIDV-FGVTHRESIMNVNVKGTQLLLEACVQASVPVFIYT 122
            F+K     + + +V+H A    V            VNV GT +L+ A  +A V  FIY 
Sbjct: 81  HFVKLLFETEKIDIVLHFAAQTHVDLSFVRAFEFTYVNVYGTHVLVSAAHEARVEKFIYV 140

Query: 123 SSIEVAGPNSYKEIIQNGHEEEPLENTWPTPYPYSKKLAE 162
           S+ EV G +  KE      E  P + T   PY  SK  AE
Sbjct: 141 STDEVYGGSLDKEF----DESSPKQPT--NPYASSKAAAE 174


>gi|56118217 UDP-galactose-4-epimerase [Homo sapiens]
          Length = 348

 Score = 40.0 bits (92), Expect = 0.003
 Identities = 55/178 (30%), Positives = 72/178 (40%), Gaps = 23/178 (12%)

Query: 1   MGWSCLVTGAGGLLGQRIVRLLVEEKELKE-IRALDKAFRP--ELREEFSKLQNRTKLTV 57
           M    LVTG  G +G   V  L+E   L   I     AFR    L E   ++Q  T  +V
Sbjct: 1   MAEKVLVTGGAGYIGSHTVLELLEAGYLPVVIDNFHNAFRGGGSLPESLRRVQELTGRSV 60

Query: 58  L--EGDILDEPFLKRACQDVS--VVIHTACIIDVFGVTHRE-SIMNVNVKGTQLLLEACV 112
              E DILD+  L+R  +  S   VIH A +  V     +      VN+ GT  LLE   
Sbjct: 61  EFEEMDILDQGALQRLFKKYSFMAVIHFAGLKAVGESVQKPLDYYRVNLTGTIQLLEIMK 120

Query: 113 QASVPVFIYTSSIEVAGPNSYKEIIQNGHEEEPLENTWPT-----PYPYSKKLAEKAV 165
              V   +++SS  V G   Y           PL+   PT     PY  SK   E+ +
Sbjct: 121 AHGVKNLVFSSSATVYGNPQYL----------PLDEAHPTGGCTNPYGKSKFFIEEMI 168


>gi|56237023 UDP-galactose-4-epimerase [Homo sapiens]
          Length = 348

 Score = 40.0 bits (92), Expect = 0.003
 Identities = 55/178 (30%), Positives = 72/178 (40%), Gaps = 23/178 (12%)

Query: 1   MGWSCLVTGAGGLLGQRIVRLLVEEKELKE-IRALDKAFRP--ELREEFSKLQNRTKLTV 57
           M    LVTG  G +G   V  L+E   L   I     AFR    L E   ++Q  T  +V
Sbjct: 1   MAEKVLVTGGAGYIGSHTVLELLEAGYLPVVIDNFHNAFRGGGSLPESLRRVQELTGRSV 60

Query: 58  L--EGDILDEPFLKRACQDVS--VVIHTACIIDVFGVTHRE-SIMNVNVKGTQLLLEACV 112
              E DILD+  L+R  +  S   VIH A +  V     +      VN+ GT  LLE   
Sbjct: 61  EFEEMDILDQGALQRLFKKYSFMAVIHFAGLKAVGESVQKPLDYYRVNLTGTIQLLEIMK 120

Query: 113 QASVPVFIYTSSIEVAGPNSYKEIIQNGHEEEPLENTWPT-----PYPYSKKLAEKAV 165
              V   +++SS  V G   Y           PL+   PT     PY  SK   E+ +
Sbjct: 121 AHGVKNLVFSSSATVYGNPQYL----------PLDEAHPTGGCTNPYGKSKFFIEEMI 168


>gi|189083684 UDP-galactose-4-epimerase [Homo sapiens]
          Length = 348

 Score = 40.0 bits (92), Expect = 0.003
 Identities = 55/178 (30%), Positives = 72/178 (40%), Gaps = 23/178 (12%)

Query: 1   MGWSCLVTGAGGLLGQRIVRLLVEEKELKE-IRALDKAFRP--ELREEFSKLQNRTKLTV 57
           M    LVTG  G +G   V  L+E   L   I     AFR    L E   ++Q  T  +V
Sbjct: 1   MAEKVLVTGGAGYIGSHTVLELLEAGYLPVVIDNFHNAFRGGGSLPESLRRVQELTGRSV 60

Query: 58  L--EGDILDEPFLKRACQDVS--VVIHTACIIDVFGVTHRE-SIMNVNVKGTQLLLEACV 112
              E DILD+  L+R  +  S   VIH A +  V     +      VN+ GT  LLE   
Sbjct: 61  EFEEMDILDQGALQRLFKKYSFMAVIHFAGLKAVGESVQKPLDYYRVNLTGTIQLLEIMK 120

Query: 113 QASVPVFIYTSSIEVAGPNSYKEIIQNGHEEEPLENTWPT-----PYPYSKKLAEKAV 165
              V   +++SS  V G   Y           PL+   PT     PY  SK   E+ +
Sbjct: 121 AHGVKNLVFSSSATVYGNPQYL----------PLDEAHPTGGCTNPYGKSKFFIEEMI 168


>gi|31542658 fatty acyl CoA reductase 2 [Homo sapiens]
          Length = 515

 Score = 32.3 bits (72), Expect = 0.70
 Identities = 57/259 (22%), Positives = 98/259 (37%), Gaps = 53/259 (20%)

Query: 2   GWSCLVTGAGGLLGQ-------------RIVRLLVEEK-----ELKEIRALDKAFRPELR 43
           G S L+TGA G LG+             +++ +LV  K     + +  + LD     +++
Sbjct: 10  GKSILITGATGFLGKVLMEKLFRTSPDLKVIYILVRPKAGQTLQQRVFQILDSKLFEKVK 69

Query: 44  EEFSKLQNRTKLTVLEGDILDEPFLKRACQDV----SVVIHTACIIDVFGVTHRESIMNV 99
           E    +  + +    + +  D    K   Q++    +++ H A  +  F  T R ++  +
Sbjct: 70  EVCPNVHEKIRAIYADLNQNDFAISKEDMQELLSCTNIIFHCAATVR-FDDTLRHAVQ-L 127

Query: 100 NVKGT-QLLLEACVQASVPVFIYTSS------------IEVAGPNSYKEIIQNGH----- 141
           NV  T QLLL A     +  FI+ S+            +    P   K+II +       
Sbjct: 128 NVTATRQLLLMASQMPKLEAFIHISTAYSNCNLKHIDEVIYPCPVEPKKIIDSLEWLDDA 187

Query: 142 ---EEEP-LENTWPTPYPYSKKLAEKAVLAANGWNLKNGDTLYTCALRPTYIYGEGGPFL 197
              E  P L   WP  Y Y+K L E  V        +    L    +RP+ +        
Sbjct: 188 IIDEITPKLIRDWPNIYTYTKALGEMVV-------QQESRNLNIAIIRPSIVGATWQEPF 240

Query: 198 SASINEALNNNGILSSVGK 216
              ++     NGI+ + GK
Sbjct: 241 PGWVDNINGPNGIIIATGK 259


>gi|150456451 hypothetical protein LOC54914 [Homo sapiens]
          Length = 1801

 Score = 28.9 bits (63), Expect = 7.8
 Identities = 19/67 (28%), Positives = 33/67 (49%), Gaps = 4/67 (5%)

Query: 306  PIYSYQPPFNRHTVTLSNSVFTFSYKKAQRDLAYKPLYSWEEAKQKTVEWVGSLVDRHKE 365
            P+ S+      H VTL   V T         L  +P   W+E  QK ++W+ S+++  KE
Sbjct: 1711 PVPSFLGRSPMHRVTLQE-VLTLLPNSMALLLQKEP---WKEQTQKFIDWLFSIMESPKE 1766

Query: 366  TLKSKTQ 372
             L ++++
Sbjct: 1767 ALSAQSR 1773


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.318    0.135    0.407 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 14,417,614
Number of Sequences: 37866
Number of extensions: 637015
Number of successful extensions: 1572
Number of sequences better than 10.0: 17
Number of HSP's better than 10.0 without gapping: 12
Number of HSP's successfully gapped in prelim test: 5
Number of HSP's that attempted gapping in prelim test: 1532
Number of HSP's gapped (non-prelim): 20
length of query: 372
length of database: 18,247,518
effective HSP length: 104
effective length of query: 268
effective length of database: 14,309,454
effective search space: 3834933672
effective search space used: 3834933672
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.