Guide to the Human Genome
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Search of human proteins with 4504477

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|4504477 4-hydroxyphenylpyruvate dioxygenase [Homo sapiens]
         (393 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|4504477 4-hydroxyphenylpyruvate dioxygenase [Homo sapiens]         802   0.0  
gi|14249394 glyoxalase domain containing 1 [Homo sapiens]              98   1e-20
gi|110349719 titin isoform N2-A [Homo sapiens]                         36   0.053
gi|110349717 titin isoform novex-2 [Homo sapiens]                      36   0.053
gi|110349713 titin isoform novex-1 [Homo sapiens]                      36   0.053
gi|110349715 titin isoform N2-B [Homo sapiens]                         36   0.053
gi|33188443 microfilament and actin filament cross-linker protei...    32   0.99 
gi|33188445 microfilament and actin filament cross-linker protei...    32   0.99 
gi|47458820 signal transducer and activator of transcription 3 i...    31   2.2  
gi|21618338 signal transducer and activator of transcription 3 i...    31   2.2  
gi|21618340 signal transducer and activator of transcription 3 i...    31   2.2  
gi|149999378 inverted formin 2 isoform 2 [Homo sapiens]                30   2.9  
gi|149999380 inverted formin 2 isoform 1 [Homo sapiens]                30   2.9  
gi|14249316 hypothetical protein LOC84800 [Homo sapiens]               30   2.9  
gi|148539554 indoleamine-pyrrole 2,3 dioxygenase-like 1 [Homo sa...    30   4.9  
gi|142356950 potassium channel tetramerisation domain containing...    29   6.4  
gi|28372531 protein phosphatase 4, regulatory subunit 2 [Homo sa...    29   8.4  
gi|150456432 unc-51-like kinase 3 [Homo sapiens]                       29   8.4  
gi|134133248 FYVE, RhoGEF and PH domain containing 3 [Homo sapiens]    29   8.4  
gi|134133265 FYVE, RhoGEF and PH domain containing 3 [Homo sapiens]    29   8.4  

>gi|4504477 4-hydroxyphenylpyruvate dioxygenase [Homo sapiens]
          Length = 393

 Score =  802 bits (2071), Expect = 0.0
 Identities = 393/393 (100%), Positives = 393/393 (100%)

Query: 1   MTTYSDKGAKPERGRFLHFHSVTFWVGNAKQAASFYCSKMGFEPLAYRGLETGSREVVSH 60
           MTTYSDKGAKPERGRFLHFHSVTFWVGNAKQAASFYCSKMGFEPLAYRGLETGSREVVSH
Sbjct: 1   MTTYSDKGAKPERGRFLHFHSVTFWVGNAKQAASFYCSKMGFEPLAYRGLETGSREVVSH 60

Query: 61  VIKQGKIVFVLSSALNPWNKEMGDHLVKHGDGVKDIAFEVEDCDYIVQKARERGAKIMRE 120
           VIKQGKIVFVLSSALNPWNKEMGDHLVKHGDGVKDIAFEVEDCDYIVQKARERGAKIMRE
Sbjct: 61  VIKQGKIVFVLSSALNPWNKEMGDHLVKHGDGVKDIAFEVEDCDYIVQKARERGAKIMRE 120

Query: 121 PWVEQDKFGKVKFAVLQTYGDTTHTLVEKMNYIGQFLPGYEAPAFMDPLLPKLPKCSLEM 180
           PWVEQDKFGKVKFAVLQTYGDTTHTLVEKMNYIGQFLPGYEAPAFMDPLLPKLPKCSLEM
Sbjct: 121 PWVEQDKFGKVKFAVLQTYGDTTHTLVEKMNYIGQFLPGYEAPAFMDPLLPKLPKCSLEM 180

Query: 181 IDHIVGNQPDQEMVSASEWYLKNLQFHRFWSVDDTQVHTEYSSLRSIVVANYEESIKMPI 240
           IDHIVGNQPDQEMVSASEWYLKNLQFHRFWSVDDTQVHTEYSSLRSIVVANYEESIKMPI
Sbjct: 181 IDHIVGNQPDQEMVSASEWYLKNLQFHRFWSVDDTQVHTEYSSLRSIVVANYEESIKMPI 240

Query: 241 NEPAPGKKKSQIQEYVDYNGGAGVQHIALKTEDIITAIRHLRERGLEFLSVPSTYYKQLR 300
           NEPAPGKKKSQIQEYVDYNGGAGVQHIALKTEDIITAIRHLRERGLEFLSVPSTYYKQLR
Sbjct: 241 NEPAPGKKKSQIQEYVDYNGGAGVQHIALKTEDIITAIRHLRERGLEFLSVPSTYYKQLR 300

Query: 301 EKLKTAKIKVKENIDALEELKILVDYDEKGYLLQIFTKPVQDRPTLFLEVIQRHNHQGFG 360
           EKLKTAKIKVKENIDALEELKILVDYDEKGYLLQIFTKPVQDRPTLFLEVIQRHNHQGFG
Sbjct: 301 EKLKTAKIKVKENIDALEELKILVDYDEKGYLLQIFTKPVQDRPTLFLEVIQRHNHQGFG 360

Query: 361 AGNFNSLFKAFEEEQNLRGNLTNMETNGVVPGM 393
           AGNFNSLFKAFEEEQNLRGNLTNMETNGVVPGM
Sbjct: 361 AGNFNSLFKAFEEEQNLRGNLTNMETNGVVPGM 393


>gi|14249394 glyoxalase domain containing 1 [Homo sapiens]
          Length = 371

 Score = 97.8 bits (242), Expect = 1e-20
 Identities = 89/347 (25%), Positives = 161/347 (46%), Gaps = 25/347 (7%)

Query: 41  GFEPLAYRGLETGSREVVSHVIKQGKIVFVLSSALNPWNKEMGDHLVKHGDGVKDIAFEV 100
           GF+PLA R ++ G R++    ++ G  VF+++          G           ++ F+V
Sbjct: 30  GFQPLASREVD-GWRQLA---LRSGDAVFLVNEGAGSGEPLYGLDPRHAVPSATNLCFDV 85

Query: 101 EDCDYIVQKARERGAKIMREPWVEQDKFGKVKFAVLQT-YGDTTHTLVEKMNYIGQFLPG 159
            D     ++    G  +   P   +D  G   +AV+ +  G  + TL+E+  Y G FLPG
Sbjct: 86  ADAGAATRELAALGCSVPVPPVRVRDAQGAATYAVVSSPAGILSLTLLERAGYRGPFLPG 145

Query: 160 YEAPAFMDPLLPKLPKCSLEMIDHIVGNQPDQEMVSASEWYLKNLQF-HRFWSV-DDTQV 217
           +       P+        +  +DH+          +   W+   L F H   S  +D ++
Sbjct: 146 FR------PVSSAPGPGWVSRVDHLTLACTPGSSPTLLRWFHDCLGFCHLPLSPGEDPEL 199

Query: 218 HTEYSS------LRSIVVANYEESI--KMPINEPAPGK--KKSQIQEYVDYNGGAGVQHI 267
             E ++      LR   +     SI   + + E  PG   ++ Q+++++  + G G+QH+
Sbjct: 200 GLEMTAGFGLGGLRLTALQAQPGSIVPTLVLAESLPGATTRQDQVEQFLARHKGPGLQHV 259

Query: 268 ALKTEDIITAIRHLRERGLEFLSVPSTYYKQLREKLKTAKIKVKENIDALEELKILVDYD 327
            L T +I+ A   +   G +FL+ P  YY+Q  ++ +      + ++  L    IL+D D
Sbjct: 260 GLYTPNIVEATEGVATAGGQFLAPPGAYYQQPGKERQIRAAGHEPHL--LARQGILLDGD 317

Query: 328 EKGYLLQIFTKPVQDRPTLFLEVIQRHNHQGFGAGNFNSLFKAFEEE 374
           +  +LLQ+FTK +    T FLE+IQR    GFG GN  +L+++ +E+
Sbjct: 318 KGKFLLQVFTKSLFTEDTFFLELIQRQGATGFGQGNIRALWQSVQEQ 364


>gi|110349719 titin isoform N2-A [Homo sapiens]
          Length = 33423

 Score = 36.2 bits (82), Expect = 0.053
 Identities = 35/141 (24%), Positives = 66/141 (46%), Gaps = 19/141 (13%)

Query: 27    GNAKQAASFYCSKMGFEPLAYRGLETGSREVVSHVIKQ---GKIVFVLSSALNPWNKEMG 83
             G A+Q       ++ F    Y   E    +VVS        G +V+VL S +NP+  E  
Sbjct: 31393 GQARQLKPGDNFRLLFTAPEYYAPEVHQHDVVSTATDMWSLGTLVYVLLSGINPFLAETN 31452

Query: 84    DHLVKH---------GDGVKDIAFEVED-CDYIV---QKARERGAKIMREPWVEQDKFGK 130
               ++++          +  K+I+ E  D  D ++   +K+R   ++ ++ PW++Q K  +
Sbjct: 31453 QQIIENIMNAEYTFDEEAFKEISIEAMDFVDRLLVKERKSRMTASEALQHPWLKQ-KIER 31511

Query: 131   VKFAVLQT--YGDTTHTLVEK 149
             V   V++T  +    HTL++K
Sbjct: 31512 VSTKVIRTLKHRRYYHTLIKK 31532


>gi|110349717 titin isoform novex-2 [Homo sapiens]
          Length = 27118

 Score = 36.2 bits (82), Expect = 0.053
 Identities = 35/141 (24%), Positives = 66/141 (46%), Gaps = 19/141 (13%)

Query: 27    GNAKQAASFYCSKMGFEPLAYRGLETGSREVVSHVIKQ---GKIVFVLSSALNPWNKEMG 83
             G A+Q       ++ F    Y   E    +VVS        G +V+VL S +NP+  E  
Sbjct: 25088 GQARQLKPGDNFRLLFTAPEYYAPEVHQHDVVSTATDMWSLGTLVYVLLSGINPFLAETN 25147

Query: 84    DHLVKH---------GDGVKDIAFEVED-CDYIV---QKARERGAKIMREPWVEQDKFGK 130
               ++++          +  K+I+ E  D  D ++   +K+R   ++ ++ PW++Q K  +
Sbjct: 25148 QQIIENIMNAEYTFDEEAFKEISIEAMDFVDRLLVKERKSRMTASEALQHPWLKQ-KIER 25206

Query: 131   VKFAVLQT--YGDTTHTLVEK 149
             V   V++T  +    HTL++K
Sbjct: 25207 VSTKVIRTLKHRRYYHTLIKK 25227


>gi|110349713 titin isoform novex-1 [Homo sapiens]
          Length = 27051

 Score = 36.2 bits (82), Expect = 0.053
 Identities = 35/141 (24%), Positives = 66/141 (46%), Gaps = 19/141 (13%)

Query: 27    GNAKQAASFYCSKMGFEPLAYRGLETGSREVVSHVIKQ---GKIVFVLSSALNPWNKEMG 83
             G A+Q       ++ F    Y   E    +VVS        G +V+VL S +NP+  E  
Sbjct: 25021 GQARQLKPGDNFRLLFTAPEYYAPEVHQHDVVSTATDMWSLGTLVYVLLSGINPFLAETN 25080

Query: 84    DHLVKH---------GDGVKDIAFEVED-CDYIV---QKARERGAKIMREPWVEQDKFGK 130
               ++++          +  K+I+ E  D  D ++   +K+R   ++ ++ PW++Q K  +
Sbjct: 25081 QQIIENIMNAEYTFDEEAFKEISIEAMDFVDRLLVKERKSRMTASEALQHPWLKQ-KIER 25139

Query: 131   VKFAVLQT--YGDTTHTLVEK 149
             V   V++T  +    HTL++K
Sbjct: 25140 VSTKVIRTLKHRRYYHTLIKK 25160


>gi|110349715 titin isoform N2-B [Homo sapiens]
          Length = 26926

 Score = 36.2 bits (82), Expect = 0.053
 Identities = 35/141 (24%), Positives = 66/141 (46%), Gaps = 19/141 (13%)

Query: 27    GNAKQAASFYCSKMGFEPLAYRGLETGSREVVSHVIKQ---GKIVFVLSSALNPWNKEMG 83
             G A+Q       ++ F    Y   E    +VVS        G +V+VL S +NP+  E  
Sbjct: 24896 GQARQLKPGDNFRLLFTAPEYYAPEVHQHDVVSTATDMWSLGTLVYVLLSGINPFLAETN 24955

Query: 84    DHLVKH---------GDGVKDIAFEVED-CDYIV---QKARERGAKIMREPWVEQDKFGK 130
               ++++          +  K+I+ E  D  D ++   +K+R   ++ ++ PW++Q K  +
Sbjct: 24956 QQIIENIMNAEYTFDEEAFKEISIEAMDFVDRLLVKERKSRMTASEALQHPWLKQ-KIER 25014

Query: 131   VKFAVLQT--YGDTTHTLVEK 149
             V   V++T  +    HTL++K
Sbjct: 25015 VSTKVIRTLKHRRYYHTLIKK 25035


>gi|33188443 microfilament and actin filament cross-linker protein
            isoform b [Homo sapiens]
          Length = 5938

 Score = 32.0 bits (71), Expect = 0.99
 Identities = 30/108 (27%), Positives = 50/108 (46%), Gaps = 11/108 (10%)

Query: 253  QEYVDYNGGAGVQHIALKT--EDIITAIRH----LRERGLEFLSVPSTYYKQLREKLKTA 306
            ++ VD N    +  + L     D IT I+H    +R R  E L    T+ KQ +++L+TA
Sbjct: 5365 EKRVDVNSAVAMGEVILAVCHPDCITTIKHWITIIRARFEEVL----TWAKQHQQRLETA 5420

Query: 307  KIKVKENIDALEELKILVDYDEKGYLLQIFTKPVQDRPTLFLEVIQRH 354
              ++  N + LEEL   + + E   L+Q   +P+         +I  H
Sbjct: 5421 LSELVANAELLEELLAWIQWAET-TLIQRDQEPIPQNIDRVKALIAEH 5467


>gi|33188445 microfilament and actin filament cross-linker protein
            isoform a [Homo sapiens]
          Length = 5430

 Score = 32.0 bits (71), Expect = 0.99
 Identities = 30/108 (27%), Positives = 50/108 (46%), Gaps = 11/108 (10%)

Query: 253  QEYVDYNGGAGVQHIALKT--EDIITAIRH----LRERGLEFLSVPSTYYKQLREKLKTA 306
            ++ VD N    +  + L     D IT I+H    +R R  E L    T+ KQ +++L+TA
Sbjct: 4863 EKRVDVNSAVAMGEVILAVCHPDCITTIKHWITIIRARFEEVL----TWAKQHQQRLETA 4918

Query: 307  KIKVKENIDALEELKILVDYDEKGYLLQIFTKPVQDRPTLFLEVIQRH 354
              ++  N + LEEL   + + E   L+Q   +P+         +I  H
Sbjct: 4919 LSELVANAELLEELLAWIQWAET-TLIQRDQEPIPQNIDRVKALIAEH 4965


>gi|47458820 signal transducer and activator of transcription 3
           isoform 3 [Homo sapiens]
          Length = 722

 Score = 30.8 bits (68), Expect = 2.2
 Identities = 22/89 (24%), Positives = 38/89 (42%), Gaps = 6/89 (6%)

Query: 247 KKKSQIQEYVDYNGGAGVQHIALKTEDIITAIRHLRERGLEFLSVPSTYYKQLREKLKTA 306
           KK  ++Q+ V Y G   VQH  +  E I+   R+L +        P       R      
Sbjct: 282 KKLEELQQKVSYKGDPIVQHRPMLEERIVELFRNLMKSAFVVERQPCMPMHPDR------ 335

Query: 307 KIKVKENIDALEELKILVDYDEKGYLLQI 335
            + +K  +    ++++LV + E  Y L+I
Sbjct: 336 PLVIKTGVQFTTKVRLLVKFPELNYQLKI 364


>gi|21618338 signal transducer and activator of transcription 3
           isoform 2 [Homo sapiens]
          Length = 769

 Score = 30.8 bits (68), Expect = 2.2
 Identities = 22/89 (24%), Positives = 38/89 (42%), Gaps = 6/89 (6%)

Query: 247 KKKSQIQEYVDYNGGAGVQHIALKTEDIITAIRHLRERGLEFLSVPSTYYKQLREKLKTA 306
           KK  ++Q+ V Y G   VQH  +  E I+   R+L +        P       R      
Sbjct: 282 KKLEELQQKVSYKGDPIVQHRPMLEERIVELFRNLMKSAFVVERQPCMPMHPDR------ 335

Query: 307 KIKVKENIDALEELKILVDYDEKGYLLQI 335
            + +K  +    ++++LV + E  Y L+I
Sbjct: 336 PLVIKTGVQFTTKVRLLVKFPELNYQLKI 364


>gi|21618340 signal transducer and activator of transcription 3
           isoform 1 [Homo sapiens]
          Length = 770

 Score = 30.8 bits (68), Expect = 2.2
 Identities = 22/89 (24%), Positives = 38/89 (42%), Gaps = 6/89 (6%)

Query: 247 KKKSQIQEYVDYNGGAGVQHIALKTEDIITAIRHLRERGLEFLSVPSTYYKQLREKLKTA 306
           KK  ++Q+ V Y G   VQH  +  E I+   R+L +        P       R      
Sbjct: 282 KKLEELQQKVSYKGDPIVQHRPMLEERIVELFRNLMKSAFVVERQPCMPMHPDR------ 335

Query: 307 KIKVKENIDALEELKILVDYDEKGYLLQI 335
            + +K  +    ++++LV + E  Y L+I
Sbjct: 336 PLVIKTGVQFTTKVRLLVKFPELNYQLKI 364


>gi|149999378 inverted formin 2 isoform 2 [Homo sapiens]
          Length = 1240

 Score = 30.4 bits (67), Expect = 2.9
 Identities = 22/80 (27%), Positives = 40/80 (50%), Gaps = 8/80 (10%)

Query: 261 GAGVQHIA-----LKTEDIITAIRHLRERGLEFLSVPSTYYKQLREKLKTAKIKVKENID 315
           G GV  I+     L     + A+ + R+ G+E++     Y +QL + L T+ + VK+ + 
Sbjct: 86  GRGVARISDALLQLTCVSCVRAVMNSRQ-GIEYILSNQGYVRQLSQALDTSNVMVKKQV- 143

Query: 316 ALEELKILVDYDEKGYLLQI 335
             E L  L  Y  +G++L +
Sbjct: 144 -FELLAALCIYSPEGHVLTL 162


>gi|149999380 inverted formin 2 isoform 1 [Homo sapiens]
          Length = 1249

 Score = 30.4 bits (67), Expect = 2.9
 Identities = 22/80 (27%), Positives = 40/80 (50%), Gaps = 8/80 (10%)

Query: 261 GAGVQHIA-----LKTEDIITAIRHLRERGLEFLSVPSTYYKQLREKLKTAKIKVKENID 315
           G GV  I+     L     + A+ + R+ G+E++     Y +QL + L T+ + VK+ + 
Sbjct: 86  GRGVARISDALLQLTCVSCVRAVMNSRQ-GIEYILSNQGYVRQLSQALDTSNVMVKKQV- 143

Query: 316 ALEELKILVDYDEKGYLLQI 335
             E L  L  Y  +G++L +
Sbjct: 144 -FELLAALCIYSPEGHVLTL 162


>gi|14249316 hypothetical protein LOC84800 [Homo sapiens]
          Length = 234

 Score = 30.4 bits (67), Expect = 2.9
 Identities = 22/80 (27%), Positives = 40/80 (50%), Gaps = 8/80 (10%)

Query: 261 GAGVQHIA-----LKTEDIITAIRHLRERGLEFLSVPSTYYKQLREKLKTAKIKVKENID 315
           G GV  I+     L     + A+ + R+ G+E++     Y +QL + L T+ + VK+ + 
Sbjct: 86  GRGVARISDALLQLTCVSCVRAVMNSRQ-GIEYILSNQGYVRQLSQALDTSNVMVKKQV- 143

Query: 316 ALEELKILVDYDEKGYLLQI 335
             E L  L  Y  +G++L +
Sbjct: 144 -FELLAALCIYSPEGHVLTL 162


>gi|148539554 indoleamine-pyrrole 2,3 dioxygenase-like 1 [Homo
           sapiens]
          Length = 420

 Score = 29.6 bits (65), Expect = 4.9
 Identities = 27/121 (22%), Positives = 53/121 (43%), Gaps = 13/121 (10%)

Query: 221 YSSLRSIVVANYEESIKMPINEPAPGKKKSQIQEYVDYNGGAGVQHIALKTEDIITAIRH 280
           Y+ +R I ++ ++++  MP      G      QE + Y+GG+  Q   L   D    IRH
Sbjct: 244 YAGIR-IFLSGWKDNPAMPAGLMYEGVS----QEPLKYSGGSAAQSTVLHAFDEFLGIRH 298

Query: 281 LRERGLEFLSVPSTYYKQLREKLKTAKIKVKENIDALEELKILVDYDEKGYLLQIFTKPV 340
            +E G         +  ++R+ +  +     E+I +   L+  +    + +LL  + + V
Sbjct: 299 SKESG--------DFLYRMRDYMPPSHKAFIEDIHSAPSLRDYILSSGQDHLLTAYNQCV 350

Query: 341 Q 341
           Q
Sbjct: 351 Q 351


>gi|142356950 potassium channel tetramerisation domain containing 14
           [Homo sapiens]
          Length = 255

 Score = 29.3 bits (64), Expect = 6.4
 Identities = 16/69 (23%), Positives = 33/69 (47%), Gaps = 8/69 (11%)

Query: 285 GLEFLSVPSTYYKQLREKLKTAKIKVKENIDALEELKILVDYDEKGYLLQIFTKPVQDRP 344
           G  F+  PSTY++ + + L+T ++  +   +   E +         Y ++   K ++D P
Sbjct: 75  GRFFIDRPSTYFRPILDYLRTGQVPTQHIPEVYREAQF--------YEIKPLVKLLEDMP 126

Query: 345 TLFLEVIQR 353
            +F E + R
Sbjct: 127 QIFGEQVSR 135


>gi|28372531 protein phosphatase 4, regulatory subunit 2 [Homo
           sapiens]
          Length = 417

 Score = 28.9 bits (63), Expect = 8.4
 Identities = 15/55 (27%), Positives = 26/55 (47%)

Query: 181 IDHIVGNQPDQEMVSASEWYLKNLQFHRFWSVDDTQVHTEYSSLRSIVVANYEES 235
           +  +    PD++ V A    +K L+F +   V +T   T  S + S++V   E S
Sbjct: 225 VSPLKNKHPDEDAVEAEGHEVKRLRFDKEGEVRETASQTTSSEISSVMVGETEAS 279


>gi|150456432 unc-51-like kinase 3 [Homo sapiens]
          Length = 472

 Score = 28.9 bits (63), Expect = 8.4
 Identities = 23/89 (25%), Positives = 40/89 (44%), Gaps = 7/89 (7%)

Query: 264 VQHIALKTEDIITAIRHLRERGLEFLSVPSTYYKQLREKLKTAKIKVKENIDALEELKIL 323
           VQ +    E    A   L  + L+F  VP+ +Y+   ++ +  K KV + +   EELK +
Sbjct: 289 VQAVKKDQEGDSAAALSLYCKALDFF-VPALHYEVDAQRKEAIKAKVGQYVSRAEELKAI 347

Query: 324 VDYDEKGYLLQ------IFTKPVQDRPTL 346
           V    +  L Q      +  +  +D+P L
Sbjct: 348 VSSSNQALLRQGTSARDLLREMARDKPRL 376


>gi|134133248 FYVE, RhoGEF and PH domain containing 3 [Homo sapiens]
          Length = 725

 Score = 28.9 bits (63), Expect = 8.4
 Identities = 35/160 (21%), Positives = 66/160 (41%), Gaps = 14/160 (8%)

Query: 233 EESIKMPINEPAPGKKKSQIQEYVDYNGGAGVQHIALKTEDIITAIRHLRERGLEFLSVP 292
           EE I  P NE     K+ QIQ+    NG    +H+ L    I+  +  LR  G +F    
Sbjct: 361 EEDIVNPANELI---KEGQIQKLSAKNGTPQDRHLFLFNSMILYCVPKLRLMGQKF---- 413

Query: 293 STYYKQLREKLKTAKIKVKENIDALEELKILVDYDEKGYLLQIFTKPVQDRPTLFLE-VI 351
                 +REK+  + ++V++ +        ++   ++   LQ  T+  +      ++  I
Sbjct: 414 -----SVREKMDISGLQVQDIVKPNTAHTFIITGRKRSLELQTRTEEEKKEWIQIIQATI 468

Query: 352 QRHNHQGFGAGNFNSLFKAFEEEQNLRGNLTNMETNGVVP 391
           ++H         F   F   +E+ +L  ++    T+ V P
Sbjct: 469 EKHKQNSETFKAFGGAFSQ-DEDPSLSPDMPITSTSPVEP 507


>gi|134133265 FYVE, RhoGEF and PH domain containing 3 [Homo sapiens]
          Length = 725

 Score = 28.9 bits (63), Expect = 8.4
 Identities = 35/160 (21%), Positives = 66/160 (41%), Gaps = 14/160 (8%)

Query: 233 EESIKMPINEPAPGKKKSQIQEYVDYNGGAGVQHIALKTEDIITAIRHLRERGLEFLSVP 292
           EE I  P NE     K+ QIQ+    NG    +H+ L    I+  +  LR  G +F    
Sbjct: 361 EEDIVNPANELI---KEGQIQKLSAKNGTPQDRHLFLFNSMILYCVPKLRLMGQKF---- 413

Query: 293 STYYKQLREKLKTAKIKVKENIDALEELKILVDYDEKGYLLQIFTKPVQDRPTLFLE-VI 351
                 +REK+  + ++V++ +        ++   ++   LQ  T+  +      ++  I
Sbjct: 414 -----SVREKMDISGLQVQDIVKPNTAHTFIITGRKRSLELQTRTEEEKKEWIQIIQATI 468

Query: 352 QRHNHQGFGAGNFNSLFKAFEEEQNLRGNLTNMETNGVVP 391
           ++H         F   F   +E+ +L  ++    T+ V P
Sbjct: 469 EKHKQNSETFKAFGGAFSQ-DEDPSLSPDMPITSTSPVEP 507


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.318    0.136    0.403 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 15,056,488
Number of Sequences: 37866
Number of extensions: 659929
Number of successful extensions: 1539
Number of sequences better than 10.0: 20
Number of HSP's better than 10.0 without gapping: 3
Number of HSP's successfully gapped in prelim test: 17
Number of HSP's that attempted gapping in prelim test: 1531
Number of HSP's gapped (non-prelim): 22
length of query: 393
length of database: 18,247,518
effective HSP length: 104
effective length of query: 289
effective length of database: 14,309,454
effective search space: 4135432206
effective search space used: 4135432206
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 63 (28.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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