Guide to the Human Genome
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Search of human proteins with 4504169

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|4504169 glutathione synthetase [Homo sapiens]
         (474 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|4504169 glutathione synthetase [Homo sapiens]                      921   0.0  
gi|14149617 nuclear receptor coactivator 4 isoform 3 [Homo sapiens]    33   0.74 
gi|223890287 nuclear receptor coactivator 4 isoform 3 [Homo sapi...    33   0.74 
gi|223890284 nuclear receptor coactivator 4 isoform 3 [Homo sapi...    33   0.74 
gi|223890281 nuclear receptor coactivator 4 isoform 2 [Homo sapi...    33   0.74 
gi|223890278 nuclear receptor coactivator 4 isoform 1 [Homo sapi...    33   0.74 
gi|110347400 odz, odd Oz/ten-m homolog 1 isoform 3 [Homo sapiens]      32   1.6  
gi|253970446 odz, odd Oz/ten-m homolog 1 isoform 2 [Homo sapiens]      32   1.6  
gi|253970444 odz, odd Oz/ten-m homolog 1 isoform 1 [Homo sapiens]      32   1.6  
gi|156105693 PPAR-alpha interacting complex protein 285 isoform ...    31   2.8  
gi|156105695 PPAR-alpha interacting complex protein 285 isoform ...    31   2.8  
gi|32698704 tectonin beta-propeller repeat containing 1 [Homo sa...    30   3.7  
gi|24497438 interleukin 12B precursor [Homo sapiens]                   30   4.8  
gi|118600981 jumonji domain containing 1C isoform a [Homo sapiens]     30   6.2  
gi|68342036 jumonji domain containing 1C isoform b [Homo sapiens]      30   6.2  
gi|30179900 SRY (sex determining region Y)-box 1 [Homo sapiens]        29   8.1  
gi|20357504 dystonin isoform 1eB precursor [Homo sapiens]              29   8.1  
gi|118600963 Nik related kinase [Homo sapiens]                         29   8.1  

>gi|4504169 glutathione synthetase [Homo sapiens]
          Length = 474

 Score =  921 bits (2380), Expect = 0.0
 Identities = 474/474 (100%), Positives = 474/474 (100%)

Query: 1   MATNWGSLLQDKQQLEELARQAVDRALAEGVLLRTSQEPTSSEVVSYAPFTLFPSLVPSA 60
           MATNWGSLLQDKQQLEELARQAVDRALAEGVLLRTSQEPTSSEVVSYAPFTLFPSLVPSA
Sbjct: 1   MATNWGSLLQDKQQLEELARQAVDRALAEGVLLRTSQEPTSSEVVSYAPFTLFPSLVPSA 60

Query: 61  LLEQAYAVQMDFNLLVDAVSQNAAFLEQTLSSTIKQDDFTARLFDIHKQVLKEGIAQTVF 120
           LLEQAYAVQMDFNLLVDAVSQNAAFLEQTLSSTIKQDDFTARLFDIHKQVLKEGIAQTVF
Sbjct: 61  LLEQAYAVQMDFNLLVDAVSQNAAFLEQTLSSTIKQDDFTARLFDIHKQVLKEGIAQTVF 120

Query: 121 LGLNRSDYMFQRSADGSPALKQIEINTISASFGGLASRTPAVHRHVLSVLSKTKEAGKIL 180
           LGLNRSDYMFQRSADGSPALKQIEINTISASFGGLASRTPAVHRHVLSVLSKTKEAGKIL
Sbjct: 121 LGLNRSDYMFQRSADGSPALKQIEINTISASFGGLASRTPAVHRHVLSVLSKTKEAGKIL 180

Query: 181 SNNPSKGLALGIAKAWELYGSPNALVLLIAQEKERNIFDQRAIENELLARNIHVIRRTFE 240
           SNNPSKGLALGIAKAWELYGSPNALVLLIAQEKERNIFDQRAIENELLARNIHVIRRTFE
Sbjct: 181 SNNPSKGLALGIAKAWELYGSPNALVLLIAQEKERNIFDQRAIENELLARNIHVIRRTFE 240

Query: 241 DISEKGSLDQDRRLFVDGQEIAVVYFRDGYMPRQYSLQNWEARLLLERSHAAKCPDIATQ 300
           DISEKGSLDQDRRLFVDGQEIAVVYFRDGYMPRQYSLQNWEARLLLERSHAAKCPDIATQ
Sbjct: 241 DISEKGSLDQDRRLFVDGQEIAVVYFRDGYMPRQYSLQNWEARLLLERSHAAKCPDIATQ 300

Query: 301 LAGTKKVQQELSRPGMLEMLLPGQPEAVARLRATFAGLYSLDVGEEGDQAIAEALAAPSR 360
           LAGTKKVQQELSRPGMLEMLLPGQPEAVARLRATFAGLYSLDVGEEGDQAIAEALAAPSR
Sbjct: 301 LAGTKKVQQELSRPGMLEMLLPGQPEAVARLRATFAGLYSLDVGEEGDQAIAEALAAPSR 360

Query: 361 FVLKPQREGGGNNLYGEEMVQALKQLKDSEERASYILMEKIEPEPFENCLLRPGSPARVV 420
           FVLKPQREGGGNNLYGEEMVQALKQLKDSEERASYILMEKIEPEPFENCLLRPGSPARVV
Sbjct: 361 FVLKPQREGGGNNLYGEEMVQALKQLKDSEERASYILMEKIEPEPFENCLLRPGSPARVV 420

Query: 421 QCISELGIFGVYVRQEKTLVMNKHVGHLLRTKAIEHADGGVAAGVAVLDNPYPV 474
           QCISELGIFGVYVRQEKTLVMNKHVGHLLRTKAIEHADGGVAAGVAVLDNPYPV
Sbjct: 421 QCISELGIFGVYVRQEKTLVMNKHVGHLLRTKAIEHADGGVAAGVAVLDNPYPV 474


>gi|14149617 nuclear receptor coactivator 4 isoform 3 [Homo sapiens]
          Length = 614

 Score = 32.7 bits (73), Expect = 0.74
 Identities = 33/122 (27%), Positives = 54/122 (44%), Gaps = 14/122 (11%)

Query: 6   GSLLQDKQQLEELARQAVDRALAEGVLLRTSQEPTSSEVVSYAPFTLFPSLVPSALLEQA 65
           G +L+ +QQ+++  R+   +A     + R  +   S EV  Y    L   L    L +QA
Sbjct: 32  GGVLRAEQQIKDNLREV--KAQIHSCISRHLECLRSREVWLYEQVDLIYQLKEETLQQQA 89

Query: 66  ---YAVQMDFNLLV---------DAVSQNAAFLEQTLSSTIKQDDFTARLFDIHKQVLKE 113
              Y++   FN L          D  +Q +  LE+  S T+K +D T  LF+     L++
Sbjct: 90  QQLYSLLGQFNCLTHQLECTQNKDLANQVSVCLERLGSLTLKPEDSTVLLFEADTITLRQ 149

Query: 114 GI 115
            I
Sbjct: 150 TI 151


>gi|223890287 nuclear receptor coactivator 4 isoform 3 [Homo
           sapiens]
          Length = 614

 Score = 32.7 bits (73), Expect = 0.74
 Identities = 33/122 (27%), Positives = 54/122 (44%), Gaps = 14/122 (11%)

Query: 6   GSLLQDKQQLEELARQAVDRALAEGVLLRTSQEPTSSEVVSYAPFTLFPSLVPSALLEQA 65
           G +L+ +QQ+++  R+   +A     + R  +   S EV  Y    L   L    L +QA
Sbjct: 32  GGVLRAEQQIKDNLREV--KAQIHSCISRHLECLRSREVWLYEQVDLIYQLKEETLQQQA 89

Query: 66  ---YAVQMDFNLLV---------DAVSQNAAFLEQTLSSTIKQDDFTARLFDIHKQVLKE 113
              Y++   FN L          D  +Q +  LE+  S T+K +D T  LF+     L++
Sbjct: 90  QQLYSLLGQFNCLTHQLECTQNKDLANQVSVCLERLGSLTLKPEDSTVLLFEADTITLRQ 149

Query: 114 GI 115
            I
Sbjct: 150 TI 151


>gi|223890284 nuclear receptor coactivator 4 isoform 3 [Homo
           sapiens]
          Length = 614

 Score = 32.7 bits (73), Expect = 0.74
 Identities = 33/122 (27%), Positives = 54/122 (44%), Gaps = 14/122 (11%)

Query: 6   GSLLQDKQQLEELARQAVDRALAEGVLLRTSQEPTSSEVVSYAPFTLFPSLVPSALLEQA 65
           G +L+ +QQ+++  R+   +A     + R  +   S EV  Y    L   L    L +QA
Sbjct: 32  GGVLRAEQQIKDNLREV--KAQIHSCISRHLECLRSREVWLYEQVDLIYQLKEETLQQQA 89

Query: 66  ---YAVQMDFNLLV---------DAVSQNAAFLEQTLSSTIKQDDFTARLFDIHKQVLKE 113
              Y++   FN L          D  +Q +  LE+  S T+K +D T  LF+     L++
Sbjct: 90  QQLYSLLGQFNCLTHQLECTQNKDLANQVSVCLERLGSLTLKPEDSTVLLFEADTITLRQ 149

Query: 114 GI 115
            I
Sbjct: 150 TI 151


>gi|223890281 nuclear receptor coactivator 4 isoform 2 [Homo
           sapiens]
          Length = 630

 Score = 32.7 bits (73), Expect = 0.74
 Identities = 33/122 (27%), Positives = 54/122 (44%), Gaps = 14/122 (11%)

Query: 6   GSLLQDKQQLEELARQAVDRALAEGVLLRTSQEPTSSEVVSYAPFTLFPSLVPSALLEQA 65
           G +L+ +QQ+++  R+   +A     + R  +   S EV  Y    L   L    L +QA
Sbjct: 48  GGVLRAEQQIKDNLREV--KAQIHSCISRHLECLRSREVWLYEQVDLIYQLKEETLQQQA 105

Query: 66  ---YAVQMDFNLLV---------DAVSQNAAFLEQTLSSTIKQDDFTARLFDIHKQVLKE 113
              Y++   FN L          D  +Q +  LE+  S T+K +D T  LF+     L++
Sbjct: 106 QQLYSLLGQFNCLTHQLECTQNKDLANQVSVCLERLGSLTLKPEDSTVLLFEADTITLRQ 165

Query: 114 GI 115
            I
Sbjct: 166 TI 167


>gi|223890278 nuclear receptor coactivator 4 isoform 1 [Homo
           sapiens]
          Length = 650

 Score = 32.7 bits (73), Expect = 0.74
 Identities = 33/122 (27%), Positives = 54/122 (44%), Gaps = 14/122 (11%)

Query: 6   GSLLQDKQQLEELARQAVDRALAEGVLLRTSQEPTSSEVVSYAPFTLFPSLVPSALLEQA 65
           G +L+ +QQ+++  R+   +A     + R  +   S EV  Y    L   L    L +QA
Sbjct: 48  GGVLRAEQQIKDNLREV--KAQIHSCISRHLECLRSREVWLYEQVDLIYQLKEETLQQQA 105

Query: 66  ---YAVQMDFNLLV---------DAVSQNAAFLEQTLSSTIKQDDFTARLFDIHKQVLKE 113
              Y++   FN L          D  +Q +  LE+  S T+K +D T  LF+     L++
Sbjct: 106 QQLYSLLGQFNCLTHQLECTQNKDLANQVSVCLERLGSLTLKPEDSTVLLFEADTITLRQ 165

Query: 114 GI 115
            I
Sbjct: 166 TI 167


>gi|110347400 odz, odd Oz/ten-m homolog 1 isoform 3 [Homo sapiens]
          Length = 2725

 Score = 31.6 bits (70), Expect = 1.6
 Identities = 19/58 (32%), Positives = 29/58 (50%)

Query: 198  LYGSPNALVLLIAQEKERNIFDQRAIENELLARNIHVIRRTFEDISEKGSLDQDRRLF 255
            L G  NA ++   Q KE+N  +  A E  L A N +++   F+ I+  G +  D R F
Sbjct: 1760 LPGEHNANLIEWRQRKEQNKGNVSAFERRLRAHNRNLLSIDFDHITRTGKIYDDHRKF 1817


>gi|253970446 odz, odd Oz/ten-m homolog 1 isoform 2 [Homo sapiens]
          Length = 2731

 Score = 31.6 bits (70), Expect = 1.6
 Identities = 19/58 (32%), Positives = 29/58 (50%)

Query: 198  LYGSPNALVLLIAQEKERNIFDQRAIENELLARNIHVIRRTFEDISEKGSLDQDRRLF 255
            L G  NA ++   Q KE+N  +  A E  L A N +++   F+ I+  G +  D R F
Sbjct: 1766 LPGEHNANLIEWRQRKEQNKGNVSAFERRLRAHNRNLLSIDFDHITRTGKIYDDHRKF 1823


>gi|253970444 odz, odd Oz/ten-m homolog 1 isoform 1 [Homo sapiens]
          Length = 2732

 Score = 31.6 bits (70), Expect = 1.6
 Identities = 19/58 (32%), Positives = 29/58 (50%)

Query: 198  LYGSPNALVLLIAQEKERNIFDQRAIENELLARNIHVIRRTFEDISEKGSLDQDRRLF 255
            L G  NA ++   Q KE+N  +  A E  L A N +++   F+ I+  G +  D R F
Sbjct: 1767 LPGEHNANLIEWRQRKEQNKGNVSAFERRLRAHNRNLLSIDFDHITRTGKIYDDHRKF 1824


>gi|156105693 PPAR-alpha interacting complex protein 285 isoform 1
            [Homo sapiens]
          Length = 2649

 Score = 30.8 bits (68), Expect = 2.8
 Identities = 27/93 (29%), Positives = 41/93 (44%), Gaps = 10/93 (10%)

Query: 278  QNWEARLLLERSHAAKCPDIATQLAGTKKVQQELSRPGML--EMLLPGQ------PEAVA 329
            Q+W+     +R  A +   +     G +KV +E+ RPG L    LLP Q       EAV 
Sbjct: 2049 QDWDQERRADRQEAPRRVHLFVHHMGMEKVPEEVLRPGTLFTVELLPKQLPDLRKEEAVR 2108

Query: 330  RLRATFAGLYSLDVGEEGDQAIAEALAAPSRFV 362
             L      + S+ +G    Q +   +  PSRF+
Sbjct: 2109 GLEEASPLVTSIALGRPVPQPLCRVI--PSRFL 2139


>gi|156105695 PPAR-alpha interacting complex protein 285 isoform 2
            [Homo sapiens]
          Length = 2080

 Score = 30.8 bits (68), Expect = 2.8
 Identities = 27/93 (29%), Positives = 41/93 (44%), Gaps = 10/93 (10%)

Query: 278  QNWEARLLLERSHAAKCPDIATQLAGTKKVQQELSRPGML--EMLLPGQ------PEAVA 329
            Q+W+     +R  A +   +     G +KV +E+ RPG L    LLP Q       EAV 
Sbjct: 1480 QDWDQERRADRQEAPRRVHLFVHHMGMEKVPEEVLRPGTLFTVELLPKQLPDLRKEEAVR 1539

Query: 330  RLRATFAGLYSLDVGEEGDQAIAEALAAPSRFV 362
             L      + S+ +G    Q +   +  PSRF+
Sbjct: 1540 GLEEASPLVTSIALGRPVPQPLCRVI--PSRFL 1570


>gi|32698704 tectonin beta-propeller repeat containing 1 [Homo
           sapiens]
          Length = 1165

 Score = 30.4 bits (67), Expect = 3.7
 Identities = 30/130 (23%), Positives = 51/130 (39%), Gaps = 19/130 (14%)

Query: 258 GQEIAVVYFRDGYMPRQYSLQNWEARLL---LERSHAAKCPDIAT-------QLAGTKK- 306
           G E   VYFR G  P + S + W+A +     +RSH+     + +       ++ G+ + 
Sbjct: 350 GCEDRAVYFRQGVTPSELSGKTWKAIIAARECDRSHSGSSSSLLSAGCFFGDEVRGSGES 409

Query: 307 ------VQQELSRPGMLEMLLPGQPEAVARLRATFAGLYSLDVGEEGDQAIAEALAAPSR 360
                    E+ RPG    +LP +P   ++  AT      L  G   +  + +A  A   
Sbjct: 410 APSDTDASSEVERPGP-GQILPAEPLDDSK-NATGNSASGLGAGRTAEDTVEDACPAEGS 467

Query: 361 FVLKPQREGG 370
              +P    G
Sbjct: 468 REARPNTHPG 477


>gi|24497438 interleukin 12B precursor [Homo sapiens]
          Length = 328

 Score = 30.0 bits (66), Expect = 4.8
 Identities = 15/45 (33%), Positives = 27/45 (60%)

Query: 377 EEMVQALKQLKDSEERASYILMEKIEPEPFENCLLRPGSPARVVQ 421
           E MV A+ +LK     +S+ + + I+P+P +N  L+P   +R V+
Sbjct: 209 EVMVDAVHKLKYENYTSSFFIRDIIKPDPPKNLQLKPLKNSRQVE 253


>gi|118600981 jumonji domain containing 1C isoform a [Homo sapiens]
          Length = 2540

 Score = 29.6 bits (65), Expect = 6.2
 Identities = 12/39 (30%), Positives = 24/39 (61%)

Query: 5   WGSLLQDKQQLEELARQAVDRALAEGVLLRTSQEPTSSE 43
           W  + +DK+  E   R++VD  L E +++ +S++ T S+
Sbjct: 434 WDQIQEDKKHEEAEKRKSVDTQLQEDMIIHSSEQSTVSD 472


>gi|68342036 jumonji domain containing 1C isoform b [Homo sapiens]
          Length = 2303

 Score = 29.6 bits (65), Expect = 6.2
 Identities = 12/39 (30%), Positives = 24/39 (61%)

Query: 5   WGSLLQDKQQLEELARQAVDRALAEGVLLRTSQEPTSSE 43
           W  + +DK+  E   R++VD  L E +++ +S++ T S+
Sbjct: 215 WDQIQEDKKHEEAEKRKSVDTQLQEDMIIHSSEQSTVSD 253


>gi|30179900 SRY (sex determining region Y)-box 1 [Homo sapiens]
          Length = 391

 Score = 29.3 bits (64), Expect = 8.1
 Identities = 25/62 (40%), Positives = 28/62 (45%), Gaps = 9/62 (14%)

Query: 323 GQPEAVARLRATFAG-------LYSLDVGEEGDQAIAEALAAPSRFVLKPQR-EGGGNNL 374
           G P A A  RA   G       +Y L  GE GD A A A AA SR    PQ  +G G  +
Sbjct: 324 GSPPAPAHSRAPCPGDLREMISMY-LPAGEGGDPAAAAAAAAQSRLHSLPQHYQGAGAGV 382

Query: 375 YG 376
            G
Sbjct: 383 NG 384


>gi|20357504 dystonin isoform 1eB precursor [Homo sapiens]
          Length = 3062

 Score = 29.3 bits (64), Expect = 8.1
 Identities = 16/44 (36%), Positives = 27/44 (61%)

Query: 168  SVLSKTKEAGKILSNNPSKGLALGIAKAWELYGSPNALVLLIAQ 211
            S+L+   + G I+ +NP+K L +  A   +L  S +AL++L AQ
Sbjct: 1486 SILTYQVQTGGIIQSNPAKRLTVDEAVQCDLITSSSALLVLEAQ 1529


>gi|118600963 Nik related kinase [Homo sapiens]
          Length = 1582

 Score = 29.3 bits (64), Expect = 8.1
 Identities = 22/77 (28%), Positives = 31/77 (40%), Gaps = 1/77 (1%)

Query: 243 SEKGSLDQDRRLFVDGQEIAVVYFRDGYMPRQYSLQNWEARLLLERSHAAKCPDIATQLA 302
           SE   LDQ    F  GQ+      R G  P Q    N      LE++ A + P++  Q A
Sbjct: 508 SEPQDLDQVPEEF-QGQDQVPEQQRQGQAPEQQQRHNQVPEQELEQNQAPEQPEVQEQAA 566

Query: 303 GTKKVQQELSRPGMLEM 319
              + + E   P  L +
Sbjct: 567 EPAQAETEAEEPESLRV 583


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.317    0.133    0.373 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 16,719,981
Number of Sequences: 37866
Number of extensions: 702096
Number of successful extensions: 1754
Number of sequences better than 10.0: 18
Number of HSP's better than 10.0 without gapping: 8
Number of HSP's successfully gapped in prelim test: 10
Number of HSP's that attempted gapping in prelim test: 1746
Number of HSP's gapped (non-prelim): 18
length of query: 474
length of database: 18,247,518
effective HSP length: 106
effective length of query: 368
effective length of database: 14,233,722
effective search space: 5238009696
effective search space used: 5238009696
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 64 (29.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
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