Guide to the Human Genome
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Search of human proteins with 4504067

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|4504067 aspartate aminotransferase 1 [Homo sapiens]
         (413 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|4504067 aspartate aminotransferase 1 [Homo sapiens]                844   0.0  
gi|73486658 aspartate aminotransferase 2 precursor [Homo sapiens]     391   e-109
gi|117414139 glutamic-oxaloacetic transaminase 1-like 1 [Homo sa...   309   3e-84
gi|32567786 keratin 6L [Homo sapiens]                                  34   0.21 
gi|153791158 keratin 75 [Homo sapiens]                                 33   0.36 
gi|5031873 lectin, mannose-binding, 1 precursor [Homo sapiens]         32   1.4  
gi|20070344 threonyl-tRNA synthetase 2, mitochondrial [Homo sapi...    32   1.4  
gi|17978479 vacuolar protein sorting 16 isoform 1 [Homo sapiens]       30   3.1  
gi|109148552 keratin 3 [Homo sapiens]                                  30   3.1  
gi|52630419 sterol regulatory element binding transcription fact...    30   4.0  
gi|22547195 sterol regulatory element binding transcription fact...    30   4.0  

>gi|4504067 aspartate aminotransferase 1 [Homo sapiens]
          Length = 413

 Score =  844 bits (2181), Expect = 0.0
 Identities = 413/413 (100%), Positives = 413/413 (100%)

Query: 1   MAPPSVFAEVPQAQPVLVFKLTADFREDPDPRKVNLGVGAYRTDDCHPWVLPVVKKVEQK 60
           MAPPSVFAEVPQAQPVLVFKLTADFREDPDPRKVNLGVGAYRTDDCHPWVLPVVKKVEQK
Sbjct: 1   MAPPSVFAEVPQAQPVLVFKLTADFREDPDPRKVNLGVGAYRTDDCHPWVLPVVKKVEQK 60

Query: 61  IANDNSLNHEYLPILGLAEFRSCASRLALGDDSPALKEKRVGGVQSLGGTGALRIGADFL 120
           IANDNSLNHEYLPILGLAEFRSCASRLALGDDSPALKEKRVGGVQSLGGTGALRIGADFL
Sbjct: 61  IANDNSLNHEYLPILGLAEFRSCASRLALGDDSPALKEKRVGGVQSLGGTGALRIGADFL 120

Query: 121 ARWYNGTNNKNTPVYVSSPTWENHNAVFSAAGFKDIRSYRYWDAEKRGLDLQGFLNDLEN 180
           ARWYNGTNNKNTPVYVSSPTWENHNAVFSAAGFKDIRSYRYWDAEKRGLDLQGFLNDLEN
Sbjct: 121 ARWYNGTNNKNTPVYVSSPTWENHNAVFSAAGFKDIRSYRYWDAEKRGLDLQGFLNDLEN 180

Query: 181 APEFSIVVLHACAHNPTGIDPTPEQWKQIASVMKHRFLFPFFDSAYQGFASGNLERDAWA 240
           APEFSIVVLHACAHNPTGIDPTPEQWKQIASVMKHRFLFPFFDSAYQGFASGNLERDAWA
Sbjct: 181 APEFSIVVLHACAHNPTGIDPTPEQWKQIASVMKHRFLFPFFDSAYQGFASGNLERDAWA 240

Query: 241 IRYFVSEGFEFFCAQSFSKNFGLYNERVGNLTVVGKEPESILQVLSQMEKIVRITWSNPP 300
           IRYFVSEGFEFFCAQSFSKNFGLYNERVGNLTVVGKEPESILQVLSQMEKIVRITWSNPP
Sbjct: 241 IRYFVSEGFEFFCAQSFSKNFGLYNERVGNLTVVGKEPESILQVLSQMEKIVRITWSNPP 300

Query: 301 AQGARIVASTLSNPELFEEWTGNVKTMADRILTMRSELRARLEALKTPGTWNHITDQIGM 360
           AQGARIVASTLSNPELFEEWTGNVKTMADRILTMRSELRARLEALKTPGTWNHITDQIGM
Sbjct: 301 AQGARIVASTLSNPELFEEWTGNVKTMADRILTMRSELRARLEALKTPGTWNHITDQIGM 360

Query: 361 FSFTGLNPKQVEYLVNEKHIYLLPSGRINVSGLTTKNLDYVATSIHEAVTKIQ 413
           FSFTGLNPKQVEYLVNEKHIYLLPSGRINVSGLTTKNLDYVATSIHEAVTKIQ
Sbjct: 361 FSFTGLNPKQVEYLVNEKHIYLLPSGRINVSGLTTKNLDYVATSIHEAVTKIQ 413


>gi|73486658 aspartate aminotransferase 2 precursor [Homo sapiens]
          Length = 430

 Score =  391 bits (1004), Expect = e-109
 Identities = 199/407 (48%), Positives = 278/407 (68%), Gaps = 7/407 (1%)

Query: 5   SVFAEVPQAQPVLVFKLTADFREDPDPRKVNLGVGAYRTDDCHPWVLPVVKKVEQKIAND 64
           S +  V    P  +  +T  F+ D + +K+NLGVGAYR D+  P+VLP V+K E +IA  
Sbjct: 31  SWWTHVEMGPPDPILGVTEAFKRDTNSKKMNLGVGAYRDDNGKPYVLPSVRKAEAQIAAK 90

Query: 65  NSLNHEYLPILGLAEFRSCASRLALGDDSPALKEKRVGGVQSLGGTGALRIGADFLARWY 124
           N L+ EYLPI GLAEF   ++ LALG++S  LK  R   VQ++ GTGALRIGA FL R++
Sbjct: 91  N-LDKEYLPIGGLAEFCKASAELALGENSEVLKSGRFVTVQTISGTGALRIGASFLQRFF 149

Query: 125 NGTNNKNTPVYVSSPTWENHNAVFSAAGFKDIRSYRYWDAEKRGLDLQGFLNDLENAPEF 184
             + +    V++  PTW NH  +F  AG + ++ YRY+D +  G D  G + D+   PE 
Sbjct: 150 KFSRD----VFLPKPTWGNHTPIFRDAGMQ-LQGYRYYDPKTCGFDFTGAVEDISKIPEQ 204

Query: 185 SIVVLHACAHNPTGIDPTPEQWKQIASVMKHRFLFPFFDSAYQGFASGNLERDAWAIRYF 244
           S+++LHACAHNPTG+DP PEQWK+IA+V+K R LF FFD AYQGFASG+ ++DAWA+R+F
Sbjct: 205 SVLLLHACAHNPTGVDPRPEQWKEIATVVKKRNLFAFFDMAYQGFASGDGDKDAWAVRHF 264

Query: 245 VSEGFEFFCAQSFSKNFGLYNERVGNLTVVGKEPESILQVLSQMEKIVRITWSNPPAQGA 304
           + +G      QS++KN GLY ERVG  T+V K+ +   +V SQ++ ++R  +SNPP  GA
Sbjct: 265 IEQGINVCLCQSYAKNMGLYGERVGAFTMVCKDADEAKRVESQLKILIRPMYSNPPLNGA 324

Query: 305 RIVASTLSNPELFEEWTGNVKTMADRILTMRSELRARLEALKTPGTWNHITDQIGMFSFT 364
           RI A+ L+ P+L ++W   VK MADRI+ MR++L + L+   +   W HITDQIGMF FT
Sbjct: 325 RIAAAILNTPDLRKQWLQEVKVMADRIIGMRTQLVSNLKKEGSTHNWQHITDQIGMFCFT 384

Query: 365 GLNPKQVEYLVNEKHIYLLPSGRINVSGLTTKNLDYVATSIHEAVTK 411
           GL P+QVE L+ E  IY+   GRI+V+G+T+ N+ Y+A +IH+ VTK
Sbjct: 385 GLKPEQVERLIKEFSIYMTKDGRISVAGVTSSNVGYLAHAIHQ-VTK 430


>gi|117414139 glutamic-oxaloacetic transaminase 1-like 1 [Homo
           sapiens]
          Length = 421

 Score =  309 bits (791), Expect = 3e-84
 Identities = 164/405 (40%), Positives = 237/405 (58%), Gaps = 10/405 (2%)

Query: 5   SVFAEVPQAQPVLVFKLTADFREDPDPRKVNLGVGAYRTDDCHPWVLPVVKKVEQKIAND 64
           SVF +VP A   L   L   +++D  P K+ L      T++ HPWV  VV+K   +I+ D
Sbjct: 5   SVFMDVPLAHK-LEGSLLKTYKQDDYPNKIFLAYRVCMTNEGHPWVSLVVQKTRLQISQD 63

Query: 65  NSLNHEYLPILGLAEFRSCASRLALGDDSPALKEKRVGGVQSLGGTGALRIGADFLARWY 124
            SLN+EYLP +GL  F   +  L  G  S A+ E RVGGV ++G +GA ++G  FL  W+
Sbjct: 64  PSLNYEYLPTMGLKSFIQASLALLFGKHSQAIVENRVGGVHTVGDSGAFQLGVQFLRAWH 123

Query: 125 NGTNNKNTPVYVSSPTWENHNAVFSAAGFKDIRSYRYWDAEKRGLDLQGFLNDLENAPEF 184
                    VY+ S   E H  VF   GF  +  Y  WD +K  +D    LN +E  P  
Sbjct: 124 KDARI----VYIISSQKELHGLVFQDMGFT-VYEYSVWDPKKLCMDPDILLNVVEQIPHG 178

Query: 185 SIVVLHACAHNPTGIDPTPEQWKQIASVMKHRFLFPFFDSAYQGFASGNLERDAWAIRYF 244
            ++V+     N      TP  W ++ S++K + +FPFFD   QG  + +LE D   ++YF
Sbjct: 179 CVLVMG----NIIDCKLTPSGWAKLMSMIKSKQIFPFFDIPCQGLYTSDLEEDTRILQYF 234

Query: 245 VSEGFEFFCAQSFSKNFGLYNERVGNLTVVGKEPESILQVLSQMEKIVRITWSNPPAQGA 304
           VS+GFEFFC+QS SKNFG+Y+E VG L VV    + +L VLSQ+E + +  W NPP  GA
Sbjct: 235 VSQGFEFFCSQSLSKNFGIYDEGVGMLVVVAVNNQQLLCVLSQLEGLAQALWLNPPNTGA 294

Query: 305 RIVASTLSNPELFEEWTGNVKTMADRILTMRSELRARLEALKTPGTWNHITDQIGMFSFT 364
           R++ S L NP L  EW  ++K + + I+  + +++ +L+ L TPG+W HIT+Q G   + 
Sbjct: 295 RVITSILCNPALLGEWKQSLKEVVENIMLTKEKVKEKLQLLGTPGSWGHITEQSGTHGYL 354

Query: 365 GLNPKQVEYLVNEKHIYLLPSGRINVSGLTTKNLDYVATSIHEAV 409
           GLN +QVEYLV +KHIY+  +G+IN S +   N++Y+   I+EAV
Sbjct: 355 GLNSQQVEYLVRKKHIYIPKNGQINFSCINANNINYITEGINEAV 399


>gi|32567786 keratin 6L [Homo sapiens]
          Length = 535

 Score = 34.3 bits (77), Expect = 0.21
 Identities = 27/137 (19%), Positives = 63/137 (45%), Gaps = 10/137 (7%)

Query: 282 LQVLSQMEKIVRITWSNPPAQGARIVASTLSNPELFEEWTGNVKTMADRILTMRSELRAR 341
           ++ L Q  K++   W+    QG  +  +  +   LFE + G++++  DR+ + R  L + 
Sbjct: 160 VRFLEQQNKVLETKWALLQEQGQNLGVTRNNLEPLFEAYLGSMRSTLDRLQSERGRLDSE 219

Query: 342 LEALK--TPGTWNHITDQIGMFSFTGLNPKQVEYLVNEKHIYLLPSGRINVS---GLTTK 396
           L  ++       N   D+I   +       + E++V +K +     GR+++    G  T+
Sbjct: 220 LRNVQDLVEDFKNKYEDEINKHT-----AAENEFVVLKKDVDAAYMGRMDLHGKVGTLTQ 274

Query: 397 NLDYVATSIHEAVTKIQ 413
            +D++       ++++Q
Sbjct: 275 EIDFLQQLYEMELSQVQ 291


>gi|153791158 keratin 75 [Homo sapiens]
          Length = 551

 Score = 33.5 bits (75), Expect = 0.36
 Identities = 18/65 (27%), Positives = 31/65 (47%), Gaps = 2/65 (3%)

Query: 282 LQVLSQMEKIVRITWSNPPAQGARIVASTLSNPELFEEWTGNVKTMADRILTMRSELRAR 341
           ++ L Q  K++   W+    QG+R V   L    LF+ +T  ++   + I T R  L A 
Sbjct: 167 VRFLEQQNKVLETKWALLQEQGSRTVRQNLE--PLFDSYTSELRRQLESITTERGRLEAE 224

Query: 342 LEALK 346
           L  ++
Sbjct: 225 LRNMQ 229


>gi|5031873 lectin, mannose-binding, 1 precursor [Homo sapiens]
          Length = 510

 Score = 31.6 bits (70), Expect = 1.4
 Identities = 16/41 (39%), Positives = 19/41 (46%)

Query: 110 TGALRIGADFLARWYNGTNNKNTPVYVSSPTWENHNAVFSA 150
           TG  RIGAD LA WY        PV+ S+  W      F +
Sbjct: 113 TGRGRIGADGLAIWYAENQGLEGPVFGSADLWNGVGIFFDS 153


>gi|20070344 threonyl-tRNA synthetase 2, mitochondrial [Homo
           sapiens]
          Length = 718

 Score = 31.6 bits (70), Expect = 1.4
 Identities = 21/64 (32%), Positives = 34/64 (53%), Gaps = 1/64 (1%)

Query: 276 KEPESILQVLSQMEKIVRITWSNPPAQGARIVASTLSNPELFEEWTGNVKTMADRILTMR 335
           KEP +I   L   +KI  + W+  P Q AR ++STL++  +  +  G    + +R L   
Sbjct: 56  KEPRTIKISLPGGQKIDAVAWNTTPYQLARQISSTLADTAVAAQVNGEPYDL-ERPLETD 114

Query: 336 SELR 339
           S+LR
Sbjct: 115 SDLR 118


>gi|17978479 vacuolar protein sorting 16 isoform 1 [Homo sapiens]
          Length = 839

 Score = 30.4 bits (67), Expect = 3.1
 Identities = 33/128 (25%), Positives = 52/128 (40%), Gaps = 9/128 (7%)

Query: 182 PEFSIVVLHAC-AHNPTGIDPTPEQWKQIASVMKHRFLFPFFDSAYQGFASGNLERDAWA 240
           P+  ++   AC A  P G+ P    + Q+A    +R L  F D+ Y    + +L+     
Sbjct: 197 PDLYLLDHAACSAVTPPGLAPGVSSFLQMAVSFTYRHLALFTDTGYIWMGTASLKEKLCE 256

Query: 241 IRYFVSEGFE--FFCAQSFSKNFGLYNERVGNLTVVGKEPESILQVLSQMEKIVRITWSN 298
               +    +   +C++  SK   +       L VVG  PESI  VL +   +V      
Sbjct: 257 FNCNIRAPPKQMVWCSRPRSKERAVVVAWERRLMVVGDAPESIQFVLDEDSYLV------ 310

Query: 299 PPAQGARI 306
           P   G RI
Sbjct: 311 PELDGVRI 318


>gi|109148552 keratin 3 [Homo sapiens]
          Length = 628

 Score = 30.4 bits (67), Expect = 3.1
 Identities = 16/65 (24%), Positives = 31/65 (47%)

Query: 282 LQVLSQMEKIVRITWSNPPAQGARIVASTLSNPELFEEWTGNVKTMADRILTMRSELRAR 341
           ++ L Q  K++   W+    QG   ++ T +   LFE     +++  D IL  R  L + 
Sbjct: 216 VRFLEQQNKVLETKWNLLQQQGTSSISGTNNLEPLFENHINYLRSYLDNILGERGRLDSE 275

Query: 342 LEALK 346
           L+ ++
Sbjct: 276 LKNME 280


>gi|52630419 sterol regulatory element binding transcription factor
           1 isoform a [Homo sapiens]
          Length = 1177

 Score = 30.0 bits (66), Expect = 4.0
 Identities = 17/59 (28%), Positives = 28/59 (47%), Gaps = 7/59 (11%)

Query: 163 DAEKRGLDLQGFL------NDLENAPEFSIVVLHACAHNPTGIDPTPEQWKQIASVMKH 215
           D +K   D  G+L      +D   AP +S  +  + A   TG+DP  + W  + +V+ H
Sbjct: 858 DGDKEFSDALGYLQLLNSCSDAAGAPAYSFSISSSMA-TTTGVDPVAKWWASLTAVVIH 915


>gi|22547195 sterol regulatory element binding transcription factor
           1 isoform b [Homo sapiens]
          Length = 1147

 Score = 30.0 bits (66), Expect = 4.0
 Identities = 17/59 (28%), Positives = 28/59 (47%), Gaps = 7/59 (11%)

Query: 163 DAEKRGLDLQGFL------NDLENAPEFSIVVLHACAHNPTGIDPTPEQWKQIASVMKH 215
           D +K   D  G+L      +D   AP +S  +  + A   TG+DP  + W  + +V+ H
Sbjct: 828 DGDKEFSDALGYLQLLNSCSDAAGAPAYSFSISSSMA-TTTGVDPVAKWWASLTAVVIH 885


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.319    0.135    0.413 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 16,372,544
Number of Sequences: 37866
Number of extensions: 732369
Number of successful extensions: 1343
Number of sequences better than 10.0: 11
Number of HSP's better than 10.0 without gapping: 7
Number of HSP's successfully gapped in prelim test: 4
Number of HSP's that attempted gapping in prelim test: 1332
Number of HSP's gapped (non-prelim): 11
length of query: 413
length of database: 18,247,518
effective HSP length: 105
effective length of query: 308
effective length of database: 14,271,588
effective search space: 4395649104
effective search space used: 4395649104
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 63 (28.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
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