Guide to the Human Genome
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Search of human proteins with 4503467

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|4503467 endothelin receptor type B isoform 2 precursor [Homo
sapiens]
         (436 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|4503467 endothelin receptor type B isoform 2 precursor [Homo ...   891   0.0  
gi|169808392 endothelin receptor type B isoform 1 precursor [Hom...   810   0.0  
gi|4557547 endothelin receptor type B isoform 1 precursor [Homo ...   810   0.0  
gi|4503465 endothelin receptor type A [Homo sapiens]                  457   e-129
gi|4885361 gastrin-releasing peptide receptor [Homo sapiens]          174   2e-43
gi|239757761 PREDICTED: similar to gastrin-releasing peptide rec...   174   2e-43
gi|161484640 neuromedin B receptor [Homo sapiens]                     173   2e-43
gi|4502455 bombesin-like receptor 3 [Homo sapiens]                    167   2e-41
gi|4885323 G protein-coupled receptor 37 [Homo sapiens]               122   5e-28
gi|134244291 G-protein coupled receptor 37 like 1 [Homo sapiens]      119   7e-27
gi|39725940 opioid receptor, kappa 1 [Homo sapiens]                   114   2e-25
gi|4505447 neuropeptide Y receptor Y2 [Homo sapiens]                  112   9e-25
gi|223718055 opioid receptor, mu 1 isoform MOR-1H [Homo sapiens]      110   3e-24
gi|117940060 opioid receptor, mu 1 isoform MOR-1 [Homo sapiens]       110   3e-24
gi|223718712 opioid receptor, mu 1 isoform MOR-1B5 [Homo sapiens]     110   3e-24
gi|223718719 opioid receptor, mu 1 isoform MOR-1B2 [Homo sapiens]     110   3e-24
gi|223718077 opioid receptor, mu 1 isoform MOR-1B3 [Homo sapiens]     110   3e-24
gi|223718716 opioid receptor, mu 1 isoform MOR-1B1 [Homo sapiens]     110   3e-24
gi|117940058 opioid receptor, mu 1 isoform MOR-1A [Homo sapiens]      110   3e-24
gi|223717969 opioid receptor, mu 1 isoform MOR-1B4 [Homo sapiens]     110   3e-24
gi|117940055 opioid receptor, mu 1 isoform MOR-1O [Homo sapiens]      110   3e-24
gi|117940054 opioid receptor, mu 1 isoform MOR-1X [Homo sapiens]      110   3e-24
gi|157738685 G protein-coupled receptor 103 [Homo sapiens]            109   6e-24
gi|4758474 G protein-coupled receptor 10 [Homo sapiens]               108   7e-24
gi|4505513 opiate receptor-like 1 [Homo sapiens]                      108   1e-23
gi|33286424 opiate receptor-like 1 [Homo sapiens]                     108   1e-23
gi|149944554 somatostatin receptor 4 [Homo sapiens]                   107   2e-23
gi|167000885 galanin receptor 1 [Homo sapiens]                        107   2e-23
gi|4504683 interleukin 8 receptor beta [Homo sapiens]                 106   4e-23
gi|222080109 orexin receptor 2 [Homo sapiens]                         105   1e-22

>gi|4503467 endothelin receptor type B isoform 2 precursor [Homo
           sapiens]
          Length = 436

 Score =  891 bits (2302), Expect = 0.0
 Identities = 436/436 (100%), Positives = 436/436 (100%)

Query: 1   MQPPPSLCGRALVALVLACGLSRIWGEERGFPPDRATPLLQTAEIMTPPTKTLWPKGSNA 60
           MQPPPSLCGRALVALVLACGLSRIWGEERGFPPDRATPLLQTAEIMTPPTKTLWPKGSNA
Sbjct: 1   MQPPPSLCGRALVALVLACGLSRIWGEERGFPPDRATPLLQTAEIMTPPTKTLWPKGSNA 60

Query: 61  SLARSLAPAEVPKGDRTAGSPPRTISPPPCQGPIEIKETFKYINTVVSCLVFVLGIIGNS 120
           SLARSLAPAEVPKGDRTAGSPPRTISPPPCQGPIEIKETFKYINTVVSCLVFVLGIIGNS
Sbjct: 61  SLARSLAPAEVPKGDRTAGSPPRTISPPPCQGPIEIKETFKYINTVVSCLVFVLGIIGNS 120

Query: 121 TLLRIIYKNKCMRNGPNILIASLALGDLLHIVIDIPINVYKLLAEDWPFGAEMCKLVPFI 180
           TLLRIIYKNKCMRNGPNILIASLALGDLLHIVIDIPINVYKLLAEDWPFGAEMCKLVPFI
Sbjct: 121 TLLRIIYKNKCMRNGPNILIASLALGDLLHIVIDIPINVYKLLAEDWPFGAEMCKLVPFI 180

Query: 181 QKASVGITVLSLCALSIDRYRAVASWSRIKGIGVPKWTAVEIVLIWVVSVVLAVPEAIGF 240
           QKASVGITVLSLCALSIDRYRAVASWSRIKGIGVPKWTAVEIVLIWVVSVVLAVPEAIGF
Sbjct: 181 QKASVGITVLSLCALSIDRYRAVASWSRIKGIGVPKWTAVEIVLIWVVSVVLAVPEAIGF 240

Query: 241 DIITMDYKGSYLRICLLHPVQKTAFMQFYKTAKDWWLFSFYFCLPLAITAFFYTLMTCEM 300
           DIITMDYKGSYLRICLLHPVQKTAFMQFYKTAKDWWLFSFYFCLPLAITAFFYTLMTCEM
Sbjct: 241 DIITMDYKGSYLRICLLHPVQKTAFMQFYKTAKDWWLFSFYFCLPLAITAFFYTLMTCEM 300

Query: 301 LRKKSGMQIALNDHLKQRREVAKTVFCLVLVFALCWLPLHLSRILKLTLYNQNDPNRCEL 360
           LRKKSGMQIALNDHLKQRREVAKTVFCLVLVFALCWLPLHLSRILKLTLYNQNDPNRCEL
Sbjct: 301 LRKKSGMQIALNDHLKQRREVAKTVFCLVLVFALCWLPLHLSRILKLTLYNQNDPNRCEL 360

Query: 361 LSFLLVLDYIGINMASLNSCINPIALYLVSKRFKNCFKAGPHVGNKLVMLFSVNIECDGT 420
           LSFLLVLDYIGINMASLNSCINPIALYLVSKRFKNCFKAGPHVGNKLVMLFSVNIECDGT
Sbjct: 361 LSFLLVLDYIGINMASLNSCINPIALYLVSKRFKNCFKAGPHVGNKLVMLFSVNIECDGT 420

Query: 421 VNQNPTMWPERKSNNN 436
           VNQNPTMWPERKSNNN
Sbjct: 421 VNQNPTMWPERKSNNN 436


>gi|169808392 endothelin receptor type B isoform 1 precursor [Homo
           sapiens]
          Length = 442

 Score =  810 bits (2092), Expect = 0.0
 Identities = 398/399 (99%), Positives = 399/399 (100%)

Query: 1   MQPPPSLCGRALVALVLACGLSRIWGEERGFPPDRATPLLQTAEIMTPPTKTLWPKGSNA 60
           MQPPPSLCGRALVALVLACGLSRIWGEERGFPPDRATPLLQTAEIMTPPTKTLWPKGSNA
Sbjct: 1   MQPPPSLCGRALVALVLACGLSRIWGEERGFPPDRATPLLQTAEIMTPPTKTLWPKGSNA 60

Query: 61  SLARSLAPAEVPKGDRTAGSPPRTISPPPCQGPIEIKETFKYINTVVSCLVFVLGIIGNS 120
           SLARSLAPAEVPKGDRTAGSPPRTISPPPCQGPIEIKETFKYINTVVSCLVFVLGIIGNS
Sbjct: 61  SLARSLAPAEVPKGDRTAGSPPRTISPPPCQGPIEIKETFKYINTVVSCLVFVLGIIGNS 120

Query: 121 TLLRIIYKNKCMRNGPNILIASLALGDLLHIVIDIPINVYKLLAEDWPFGAEMCKLVPFI 180
           TLLRIIYKNKCMRNGPNILIASLALGDLLHIVIDIPINVYKLLAEDWPFGAEMCKLVPFI
Sbjct: 121 TLLRIIYKNKCMRNGPNILIASLALGDLLHIVIDIPINVYKLLAEDWPFGAEMCKLVPFI 180

Query: 181 QKASVGITVLSLCALSIDRYRAVASWSRIKGIGVPKWTAVEIVLIWVVSVVLAVPEAIGF 240
           QKASVGITVLSLCALSIDRYRAVASWSRIKGIGVPKWTAVEIVLIWVVSVVLAVPEAIGF
Sbjct: 181 QKASVGITVLSLCALSIDRYRAVASWSRIKGIGVPKWTAVEIVLIWVVSVVLAVPEAIGF 240

Query: 241 DIITMDYKGSYLRICLLHPVQKTAFMQFYKTAKDWWLFSFYFCLPLAITAFFYTLMTCEM 300
           DIITMDYKGSYLRICLLHPVQKTAFMQFYKTAKDWWLFSFYFCLPLAITAFFYTLMTCEM
Sbjct: 241 DIITMDYKGSYLRICLLHPVQKTAFMQFYKTAKDWWLFSFYFCLPLAITAFFYTLMTCEM 300

Query: 301 LRKKSGMQIALNDHLKQRREVAKTVFCLVLVFALCWLPLHLSRILKLTLYNQNDPNRCEL 360
           LRKKSGMQIALNDHLKQRREVAKTVFCLVLVFALCWLPLHLSRILKLTLYNQNDPNRCEL
Sbjct: 301 LRKKSGMQIALNDHLKQRREVAKTVFCLVLVFALCWLPLHLSRILKLTLYNQNDPNRCEL 360

Query: 361 LSFLLVLDYIGINMASLNSCINPIALYLVSKRFKNCFKA 399
           LSFLLVLDYIGINMASLNSCINPIALYLVSKRFKNCFK+
Sbjct: 361 LSFLLVLDYIGINMASLNSCINPIALYLVSKRFKNCFKS 399


>gi|4557547 endothelin receptor type B isoform 1 precursor [Homo
           sapiens]
          Length = 442

 Score =  810 bits (2092), Expect = 0.0
 Identities = 398/399 (99%), Positives = 399/399 (100%)

Query: 1   MQPPPSLCGRALVALVLACGLSRIWGEERGFPPDRATPLLQTAEIMTPPTKTLWPKGSNA 60
           MQPPPSLCGRALVALVLACGLSRIWGEERGFPPDRATPLLQTAEIMTPPTKTLWPKGSNA
Sbjct: 1   MQPPPSLCGRALVALVLACGLSRIWGEERGFPPDRATPLLQTAEIMTPPTKTLWPKGSNA 60

Query: 61  SLARSLAPAEVPKGDRTAGSPPRTISPPPCQGPIEIKETFKYINTVVSCLVFVLGIIGNS 120
           SLARSLAPAEVPKGDRTAGSPPRTISPPPCQGPIEIKETFKYINTVVSCLVFVLGIIGNS
Sbjct: 61  SLARSLAPAEVPKGDRTAGSPPRTISPPPCQGPIEIKETFKYINTVVSCLVFVLGIIGNS 120

Query: 121 TLLRIIYKNKCMRNGPNILIASLALGDLLHIVIDIPINVYKLLAEDWPFGAEMCKLVPFI 180
           TLLRIIYKNKCMRNGPNILIASLALGDLLHIVIDIPINVYKLLAEDWPFGAEMCKLVPFI
Sbjct: 121 TLLRIIYKNKCMRNGPNILIASLALGDLLHIVIDIPINVYKLLAEDWPFGAEMCKLVPFI 180

Query: 181 QKASVGITVLSLCALSIDRYRAVASWSRIKGIGVPKWTAVEIVLIWVVSVVLAVPEAIGF 240
           QKASVGITVLSLCALSIDRYRAVASWSRIKGIGVPKWTAVEIVLIWVVSVVLAVPEAIGF
Sbjct: 181 QKASVGITVLSLCALSIDRYRAVASWSRIKGIGVPKWTAVEIVLIWVVSVVLAVPEAIGF 240

Query: 241 DIITMDYKGSYLRICLLHPVQKTAFMQFYKTAKDWWLFSFYFCLPLAITAFFYTLMTCEM 300
           DIITMDYKGSYLRICLLHPVQKTAFMQFYKTAKDWWLFSFYFCLPLAITAFFYTLMTCEM
Sbjct: 241 DIITMDYKGSYLRICLLHPVQKTAFMQFYKTAKDWWLFSFYFCLPLAITAFFYTLMTCEM 300

Query: 301 LRKKSGMQIALNDHLKQRREVAKTVFCLVLVFALCWLPLHLSRILKLTLYNQNDPNRCEL 360
           LRKKSGMQIALNDHLKQRREVAKTVFCLVLVFALCWLPLHLSRILKLTLYNQNDPNRCEL
Sbjct: 301 LRKKSGMQIALNDHLKQRREVAKTVFCLVLVFALCWLPLHLSRILKLTLYNQNDPNRCEL 360

Query: 361 LSFLLVLDYIGINMASLNSCINPIALYLVSKRFKNCFKA 399
           LSFLLVLDYIGINMASLNSCINPIALYLVSKRFKNCFK+
Sbjct: 361 LSFLLVLDYIGINMASLNSCINPIALYLVSKRFKNCFKS 399


>gi|4503465 endothelin receptor type A [Homo sapiens]
          Length = 427

 Score =  457 bits (1177), Expect = e-129
 Identities = 212/316 (67%), Positives = 268/316 (84%), Gaps = 8/316 (2%)

Query: 90  CQGPIEIKETFKYINTVVSCLVFVLGIIGNSTLLRIIYKNKCMRNGPNILIASLALGDLL 149
           C    +I   FKYINTV+SC +F++G++GN+TLLRIIY+NKCMRNGPN LIASLALGDL+
Sbjct: 69  CPQQTKITSAFKYINTVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLI 128

Query: 150 HIVIDIPINVYKLLAEDWPF-----GAEMCKLVPFIQKASVGITVLSLCALSIDRYRAVA 204
           ++VID+PINV+KLLA  WPF     G  +CKL PF+QK+SVGITVL+LCALS+DRYRAVA
Sbjct: 129 YVVIDLPINVFKLLAGRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVA 188

Query: 205 SWSRIKGIGVPKWTAVEIVLIWVVSVVLAVPEAIGFDIITMDYKGSYLRICLLHPVQKTA 264
           SWSR++GIG+P  TA+EIV IW++S +LA+PEAIGF ++  +Y+G   + C+L+   K  
Sbjct: 189 SWSRVQGIGIPLVTAIEIVSIWILSFILAIPEAIGFVMVPFEYRGEQHKTCMLNATSK-- 246

Query: 265 FMQFYKTAKDWWLFSFYFCLPLAITAFFYTLMTCEMLRKKSG-MQIALNDHLKQRREVAK 323
           FM+FY+  KDWWLF FYFC+PL  TA FYTLMTCEML +++G ++IAL++HLKQRREVAK
Sbjct: 247 FMEFYQDVKDWWLFGFYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAK 306

Query: 324 TVFCLVLVFALCWLPLHLSRILKLTLYNQNDPNRCELLSFLLVLDYIGINMASLNSCINP 383
           TVFCLV++FALCW PLHLSRILK T+YN+ D NRCELLSFLL++DYIGIN+A++NSCINP
Sbjct: 307 TVFCLVVIFALCWFPLHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINP 366

Query: 384 IALYLVSKRFKNCFKA 399
           IALY VSK+FKNCF++
Sbjct: 367 IALYFVSKKFKNCFQS 382


>gi|4885361 gastrin-releasing peptide receptor [Homo sapiens]
          Length = 384

 Score =  174 bits (440), Expect = 2e-43
 Identities = 102/302 (33%), Positives = 167/302 (55%), Gaps = 15/302 (4%)

Query: 102 YINTVVSCLVFVLGIIGNSTLLRIIYKNKCMRNGPNILIASLALGDLLHIVIDIPINVYK 161
           Y+   V  ++ ++G+IGN TL++I    K MRN PN+ I+SLALGDLL ++   P++  +
Sbjct: 41  YVIPAVYGVIILIGLIGNITLIKIFCTVKSMRNVPNLFISSLALGDLLLLITCAPVDASR 100

Query: 162 LLAEDWPFGAEMCKLVPFIQKASVGITVLSLCALSIDRYRAVASWSRIKGIGVPKWTAVE 221
            LA+ W FG   CKL+PFIQ  SVG++V +L ALS DRY+A+     I+         ++
Sbjct: 101 YLADRWLFGRIGCKLIPFIQLTSVGVSVFTLTALSADRYKAIVRPMDIQASHALMKICLK 160

Query: 222 IVLIWVVSVVLAVPEAIGFDIITMDYKGSYLRI--CLLHPVQKTAFMQFYKTAKDWWLFS 279
              IW++S++LA+PEA+  D+     + +      C  +P       + +  A     F 
Sbjct: 161 AAFIWIISMLLAIPEAVFSDLHPFHEESTNQTFISCAPYPHSNELHPKIHSMAS----FL 216

Query: 280 FYFCLPLAITAFFYTLMTCEMLRKKSGMQIALNDHLKQ----RREVAKTVFCLVLVFALC 335
            ++ +PL+I + +Y  +   +++    + +  N H+K+    R+ +AKTV   V +FA C
Sbjct: 217 VFYVIPLSIISVYYYFIAKNLIQSAYNLPVEGNIHVKKQIESRKRLAKTVLVFVGLFAFC 276

Query: 336 WLPLHLSRILKLTLYNQNDPNRCELLSFLLVLDYIGINMASLNSCINPIALYLVSKRFKN 395
           WLP H+  + +   Y++ D +   +L F  V       +A  NSC+NP ALYL+SK F+ 
Sbjct: 277 WLPNHVIYLYRSYHYSEVDTS---MLHF--VTSICARLLAFTNSCVNPFALYLLSKSFRK 331

Query: 396 CF 397
            F
Sbjct: 332 QF 333


>gi|239757761 PREDICTED: similar to gastrin-releasing peptide
           receptor [Homo sapiens]
          Length = 368

 Score =  174 bits (440), Expect = 2e-43
 Identities = 102/302 (33%), Positives = 167/302 (55%), Gaps = 15/302 (4%)

Query: 102 YINTVVSCLVFVLGIIGNSTLLRIIYKNKCMRNGPNILIASLALGDLLHIVIDIPINVYK 161
           Y+   V  ++ ++G+IGN TL++I    K MRN PN+ I+SLALGDLL ++   P++  +
Sbjct: 25  YVIPAVYGVIILIGLIGNITLIKIFCTVKSMRNVPNLFISSLALGDLLLLITCAPVDASR 84

Query: 162 LLAEDWPFGAEMCKLVPFIQKASVGITVLSLCALSIDRYRAVASWSRIKGIGVPKWTAVE 221
            LA+ W FG   CKL+PFIQ  SVG++V +L ALS DRY+A+     I+         ++
Sbjct: 85  YLADRWLFGRIGCKLIPFIQLTSVGVSVFTLTALSADRYKAIVRPMDIQASHALMKICLK 144

Query: 222 IVLIWVVSVVLAVPEAIGFDIITMDYKGSYLRI--CLLHPVQKTAFMQFYKTAKDWWLFS 279
              IW++S++LA+PEA+  D+     + +      C  +P       + +  A     F 
Sbjct: 145 AAFIWIISMLLAIPEAVFSDLHPFHEESTNQTFISCAPYPHSNELHPKIHSMAS----FL 200

Query: 280 FYFCLPLAITAFFYTLMTCEMLRKKSGMQIALNDHLKQ----RREVAKTVFCLVLVFALC 335
            ++ +PL+I + +Y  +   +++    + +  N H+K+    R+ +AKTV   V +FA C
Sbjct: 201 VFYVIPLSIISVYYYFIAKNLIQSAYNLPVEGNIHVKKQIESRKRLAKTVLVFVGLFAFC 260

Query: 336 WLPLHLSRILKLTLYNQNDPNRCELLSFLLVLDYIGINMASLNSCINPIALYLVSKRFKN 395
           WLP H+  + +   Y++ D +   +L F  V       +A  NSC+NP ALYL+SK F+ 
Sbjct: 261 WLPNHVIYLYRSYHYSEVDTS---MLHF--VTSICARLLAFTNSCVNPFALYLLSKSFRK 315

Query: 396 CF 397
            F
Sbjct: 316 QF 317


>gi|161484640 neuromedin B receptor [Homo sapiens]
          Length = 390

 Score =  173 bits (439), Expect = 2e-43
 Identities = 107/351 (30%), Positives = 181/351 (51%), Gaps = 16/351 (4%)

Query: 63  ARSLAPAEVPKGDRTAGSPPRTISPP--PCQGPIEIKETFKYINTVVSCLVFVLGIIGNS 120
           ++SL+   V  G   +GS P        P       +   + +   +  L+  +G++GN 
Sbjct: 3   SKSLSNLSVTTGANESGSVPEGWERDFLPASDGTTTELVIRCVIPSLYLLIITVGLLGNI 62

Query: 121 TLLRIIYKNKCMRNGPNILIASLALGDLLHIVIDIPINVYKLLAEDWPFGAEMCKLVPFI 180
            L++I   N  MR+ PNI I++LA GDLL ++  +P++  +   ++W FG   CKL+P I
Sbjct: 63  MLVKIFITNSAMRSVPNIFISNLAAGDLLLLLTCVPVDASRYFFDEWMFGKVGCKLIPVI 122

Query: 181 QKASVGITVLSLCALSIDRYRAVASWSRIKGIGVPKWTAVEIVLIWVVSVVLAVPEAIGF 240
           Q  SVG++V +L ALS DRYRA+ +   ++  G    T V+ + IWVVSV+LAVPEA+  
Sbjct: 123 QLTSVGVSVFTLTALSADRYRAIVNPMDMQTSGALLRTCVKAMGIWVVSVLLAVPEAVFS 182

Query: 241 DIITM-DYKGSYLRICLLHPVQKTAFMQFYKTAKDWWLFSFYFCLPLAITAFFYTLMTCE 299
           ++  +     S    C+ +P       + +       +F  YF +PLAI + +Y  +   
Sbjct: 183 EVARISSLDNSSFTACIPYPQTDELHPKIHSVL----IFLVYFLIPLAIISIYYYHIAKT 238

Query: 300 MLRKKSGMQIALNDHLKQRREVAKTVFCLVLVFA----LCWLPLHLSRILKLTLYNQNDP 355
           +++    +    N+H K++ E  K +  +VLVF      CW P H+  + +   YN+ DP
Sbjct: 239 LIKSAHNLPGEYNEHTKKQMETRKRLAKIVLVFVGCFIFCWFPNHILYMYRSFNYNEIDP 298

Query: 356 NRCELLSFLLVLDYIGINMASLNSCINPIALYLVSKRFKNCFKAGPHVGNK 406
           +        +++  +   ++  NSC+NP ALYL+S+ F+  F +    G K
Sbjct: 299 SLGH-----MIVTLVARVLSFGNSCVNPFALYLLSESFRRHFNSQLCCGRK 344


>gi|4502455 bombesin-like receptor 3 [Homo sapiens]
          Length = 399

 Score =  167 bits (422), Expect = 2e-41
 Identities = 98/301 (32%), Positives = 158/301 (52%), Gaps = 16/301 (5%)

Query: 106 VVSCLVFVLGIIGNSTLLRIIYKNKCMRNGPNILIASLALGDLLHIVIDIPINVYKLLAE 165
           +   ++  +GI+GN+ L+++ +K K M+  PNI I SLA GDLL ++  +P++    LAE
Sbjct: 52  ITYAVIISVGILGNAILIKVFFKTKSMQTVPNIFITSLAFGDLLLLLTCVPVDATHYLAE 111

Query: 166 DWPFGAEMCKLVPFIQKASVGITVLSLCALSIDRYRAVASWSRIKGIGVPKWTAVEIVLI 225
            W FG   CK++ FI+  SVG++V +L  LS DRY+AV      +       T V+   +
Sbjct: 112 GWLFGRIGCKVLSFIRLTSVGVSVFTLTILSADRYKAVVKPLERQPSNAILKTCVKAGCV 171

Query: 226 WVVSVVLAVPEAIGFDIITM--DYKGSYLRICLLHPVQKTAFMQFYKTAKDWWLFSFYFC 283
           W+VS++ A+PEAI  ++ T     K      C  +PV K    + +        F  ++ 
Sbjct: 172 WIVSMIFALPEAIFSNVYTFRDPNKNMTFESCTSYPVSKKLLQEIHSLL----CFLVFYI 227

Query: 284 LPLAITAFFYTLMTCEMLRKKSGMQIALNDH----LKQRREVAKTVFCLVLVFALCWLPL 339
           +PL+I + +Y+L+   + +    +      H    ++ R+ +A+TV  LV +FALCWLP 
Sbjct: 228 IPLSIISVYYSLIARTLYKSTLNIPTEEQSHARKQIESRKRIARTVLVLVALFALCWLPN 287

Query: 340 HLSRIL-KLTLYNQNDPNRCELLSFLLVLDYIGINMASLNSCINPIALYLVSKRFKNCFK 398
           HL  +    T     DP+     +   +       +A  NSC+NP ALY +SK F+  FK
Sbjct: 288 HLLYLYHSFTSQTYVDPS-----AMHFIFTIFSRVLAFSNSCVNPFALYWLSKSFQKHFK 342

Query: 399 A 399
           A
Sbjct: 343 A 343


>gi|4885323 G protein-coupled receptor 37 [Homo sapiens]
          Length = 613

 Score =  122 bits (307), Expect = 5e-28
 Identities = 92/336 (27%), Positives = 153/336 (45%), Gaps = 17/336 (5%)

Query: 72  PKGDRTAGSPPRTISPPPCQGPIEIKETFKYINTVVSCLVFVLGIIGNSTLLRIIYKNKC 131
           P G R   S  R +       P+  +    Y    +S ++F  GIIGN  ++ I+  N  
Sbjct: 232 PGGPRRGNSTNRRVRLKNPFYPLTQESYGAYAVMCLSVVIFGTGIIGNLAVMCIVCHNYY 291

Query: 132 MRNGPNILIASLALGDLLHIVIDIPINVYKLLAEDWPFGAEMCKLVPFIQKASVGITVLS 191
           MR+  N L+A+LA  D L I   +P+ ++  L + W      CK+VP+I+ AS+G+T  +
Sbjct: 292 MRSISNSLLANLAFWDFLIIFFCLPLVIFHELTKKWLLEDFSCKIVPYIEVASLGVTTFT 351

Query: 192 LCALSIDRYRAVASWSR-IKGIGVPKWTAVEIVLIWVVSVVLAVPEAIGFDIITMDYKGS 250
           LCAL IDR+RA  +     + I     T  ++ +IWV +++LA+PE +   +   D   S
Sbjct: 352 LCALCIDRFRAATNVQMYYEMIENCSSTTAKLAVIWVGALLLALPEVVLRQLSKEDLGFS 411

Query: 251 --------YLRICLLHPVQKTAFMQFYKTAKDWWLFSFYFCLPLAITAFFYTLMTCEMLR 302
                    ++I    P         Y +A+ WW F  YFCLP   T    +L+T   +R
Sbjct: 412 GRAPAERCIIKISPDLPDTIYVLALTYDSARLWWYFGCYFCLPTLFT-ITCSLVTARKIR 470

Query: 303 KKSGMQIALND-HLKQRREVAKTVFCLVLVFALCWLPLHLSRILKLTLYNQNDPNRCELL 361
           K        N   ++   ++  TV  L +++  C +P ++  I+   +         +LL
Sbjct: 471 KAEKACTRGNKRQIQLESQMNCTVVALTILYGFCIIPENICNIVTAYMATGVSQQTMDLL 530

Query: 362 SFLLVLDYIGINMASLNSCINPIALYLVSKRFKNCF 397
           +       I   +    SC+ P+ L+ + K F   F
Sbjct: 531 NI------ISQFLLFFKSCVTPVLLFCLCKPFSRAF 560


>gi|134244291 G-protein coupled receptor 37 like 1 [Homo sapiens]
          Length = 481

 Score =  119 bits (297), Expect = 7e-27
 Identities = 101/400 (25%), Positives = 180/400 (45%), Gaps = 58/400 (14%)

Query: 13  VALVLACGLSRIWG-------------------EERGFPPDRATPLLQT-----AEIMTP 48
           +A++LA GLSR+ G                    +RG   + A  + Q      AE   P
Sbjct: 11  LAVILAVGLSRVSGGAPLHLGRHRAETQEQQSRSKRGTEDEEAKGVQQYVPEEWAEYPRP 70

Query: 49  -------PTKTLWPKGSNASLARSLAPAEVPKGDRTAGSPPRTISPPPCQGPIEIKETFK 101
                  PTK L     N         +         G+P + +       P+       
Sbjct: 71  IHPAGLQPTKPLVATSPNPGKDGGTPDSGQELRGNLTGAPGQRLQIQNPLYPVTESSYSA 130

Query: 102 YINTVVSCLVFVLGIIGNSTLLRIIYKNKCMRNGPNILIASLALGDLLHIVIDIPINVYK 161
           Y   +++ +VF +GI+GN +++ I++ +  +++  N ++ASLAL D L +   +PI ++ 
Sbjct: 131 YAIMLLALVVFAVGIVGNLSVMCIVWHSYYLKSAWNSILASLALWDFLVLFFCLPIVIFN 190

Query: 162 LLAEDWPFGAEMCKLVPFIQKASVGITVLSLCALSIDRYR-AVASWSRIKGIGVPKWTAV 220
            + +    G   C+ VPF++ +S+G+T  SLCAL IDR+  A ++  +++ I   +    
Sbjct: 191 EITKQRLLGDVSCRAVPFMEVSSLGVTTFSLCALGIDRFHVATSTLPKVRPIERCQSILA 250

Query: 221 EIVLIWVVSVVLAVPEAIGFDII-----TMDYKGSYLRICLLHPVQKT-----AFMQFYK 270
           ++ +IWV S+ LAVPE + + +      TM      L  C++ P         + +  Y+
Sbjct: 251 KLAVIWVGSMTLAVPELLLWQLAQEPAPTM----GTLDSCIMKPSASLPESLYSLVMTYQ 306

Query: 271 TAKDWWLFSFYFCLPLAITAFFYTLMTCEM----LRKKSG--MQIALNDHLKQRREVAKT 324
            A+ WW F  YFCLP+  T      +TC++    +R   G   +   + H +   ++  T
Sbjct: 307 NARMWWYFGCYFCLPILFT------VTCQLVTWRVRGPPGRKSECRASKHEQCESQLNST 360

Query: 325 VFCLVLVFALCWLPLHLSRILKLTLYNQNDPNRCELLSFL 364
           V  L +V+A C LP ++  I+   L  +      +LL  +
Sbjct: 361 VVGLTVVYAFCTLPENVCNIVVAYLSTELTRQTLDLLGLI 400


>gi|39725940 opioid receptor, kappa 1 [Homo sapiens]
          Length = 380

 Score =  114 bits (284), Expect = 2e-25
 Identities = 90/336 (26%), Positives = 148/336 (44%), Gaps = 38/336 (11%)

Query: 72  PKGDRTAGSPPRTISPPPCQGPIEIKETFKYINTVVSCLVFVLGIIGNSTLLRIIYKNKC 131
           P  + +AGS    + P        I      I T V  +VFV+G++GNS ++ +I +   
Sbjct: 36  PDSNGSAGSEDAQLEPA------HISPAIPVIITAVYSVVFVVGLVGNSLVMFVIIRYTK 89

Query: 132 MRNGPNILIASLALGDLLHIVIDIPINVYKLLAEDWPFGAEMCKLVPFIQKASVGITVLS 191
           M+   NI I +LAL D L +   +P      L   WPFG  +CK+V  I   ++  ++ +
Sbjct: 90  MKTATNIYIFNLALADAL-VTTTMPFQSTVYLMNSWPFGDVLCKIVISIDYYNMFTSIFT 148

Query: 192 LCALSIDRYRAVASWSRIKGIGVPKWTAVEIVLIWVVSVVLAVPEAIGFDIITMDYKGSY 251
           L  +S+DRY AV    +      P    +  + IW++S       ++G   I +      
Sbjct: 149 LTMMSVDRYIAVCHPVKALDFRTPLKAKIINICIWLLS------SSVGISAIVLGGTKVR 202

Query: 252 LRICLLHPVQKTAFMQFYKTAKDWW-------LFSFYFCLPLAITAFFYTLMTCEMLRKK 304
             + ++        +QF      WW       +F F F +P+ I    YTLM   +LR K
Sbjct: 203 EDVDVIE-----CSLQFPDDDYSWWDLFMKICVFIFAFVIPVLIIIVCYTLM---ILRLK 254

Query: 305 SGMQIALNDHLKQR--REVAKTVFCLVLVFALCWLPLHLSRILKLTLYNQNDPNRCELLS 362
           S +++      K R  R + + V  +V VF +CW P+H+   + +        +   L S
Sbjct: 255 S-VRLLSGSREKDRNLRRITRLVLVVVAVFVVCWTPIHI--FILVEALGSTSHSTAALSS 311

Query: 363 FLLVLDYIGINMASLNSCINPIALYLVSKRFKNCFK 398
           +     Y  I +   NS +NPI    + + FK CF+
Sbjct: 312 Y-----YFCIALGYTNSSLNPILYAFLDENFKRCFR 342


>gi|4505447 neuropeptide Y receptor Y2 [Homo sapiens]
          Length = 381

 Score =  112 bits (279), Expect = 9e-25
 Identities = 90/334 (26%), Positives = 154/334 (46%), Gaps = 25/334 (7%)

Query: 68  PAEVPKGDRTAGSPPRTISPPPCQGPIEIKETFKYINTVVSCLVFVLGIIGNSTLLRIIY 127
           P   P+G+      P  I        IE++     +  +  C + +LG+IGNS ++ ++ 
Sbjct: 24  PQTTPRGELVPDPEPELIDSTKL---IEVQ----VVLILAYCSIILLGVIGNSLVIHVVI 76

Query: 128 KNKCMRNGPNILIASLALGDLLHIVIDIPINVYKLLAEDWPFGAEMCKLVPFIQKASVGI 187
           K K MR   N  IA+LA+ DLL   + +P  +   L  +W  G  +C LVP+ Q  +V +
Sbjct: 77  KFKSMRTVTNFFIANLAVADLLVNTLCLPFTLTYTLMGEWKMGPVLCHLVPYAQGLAVQV 136

Query: 188 TVLSLCALSIDRYRAVASWSRIKGIGVPKWTAVEIV-LIWVVSVVLAVPEAI--GFDIIT 244
           + ++L  +++DR+R +      K   + K  +  I+ L W +S +LA P AI   + +I 
Sbjct: 137 STITLTVIALDRHRCIVYHLESK---ISKRISFLIIGLAWGISALLASPLAIFREYSLIE 193

Query: 245 MDYKGSYLRICLLHPVQKTAFMQFYKTAKDWWLFSFYFCLPLAITAFFYTLMTCEMLRKK 304
           +      +      P ++ +    Y T          + LPL I +F YT +  ++  K 
Sbjct: 194 IIPDFEIVACTEKWPGEEKS---IYGTVYSLSSLLILYVLPLGIISFSYTRIWSKL--KN 248

Query: 305 SGMQIALNDHLKQRRE-VAKTVFCLVLVFALCWLPLHLSRILKLTLYNQNDPNRCELLSF 363
                A NDH  QRR+   K + C+V+VFA+ WLPLH        L    D    +L  +
Sbjct: 249 HVSPGAANDHYHQRRQKTTKMLVCVVVVFAVSWLPLH-----AFQLAVDIDSQVLDLKEY 303

Query: 364 LLVLDYIGINMASLNSCINPIALYLVSKRFKNCF 397
            L+     I +A  ++  NP+    ++  ++  F
Sbjct: 304 KLIFTVFHI-IAMCSTFANPLLYGWMNSNYRKAF 336


>gi|223718055 opioid receptor, mu 1 isoform MOR-1H [Homo sapiens]
          Length = 493

 Score =  110 bits (275), Expect = 3e-24
 Identities = 80/291 (27%), Positives = 133/291 (45%), Gaps = 21/291 (7%)

Query: 110 LVFVLGIIGNSTLLRIIYKNKCMRNGPNILIASLALGDLLHIVIDIPINVYKLLAEDWPF 169
           +V V+G+ GN  ++ +I +   M+   NI I +LAL D L     +P      L   WPF
Sbjct: 172 IVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADAL-ATSTLPFQSVNYLMGTWPF 230

Query: 170 GAEMCKLVPFIQKASVGITVLSLCALSIDRYRAVASWSRIKGIGVPKWTAVEIVLIWVVS 229
           G  +CK+V  I   ++  ++ +LC +S+DRY AV    +      P+   +  V  W++S
Sbjct: 231 GTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKIINVCNWILS 290

Query: 230 VVLAVPEAIGFDIITMDYKGSY-LRICLLHPVQKTAFMQFYKTAKDWWLFSFYFCLPLAI 288
             + +P  + F   T   +GS    +   HP        +++      +F F F +P+ I
Sbjct: 291 SAIGLP--VMFMATTKYRQGSIDCTLTFSHPT------WYWENLLKICVFIFAFIMPVLI 342

Query: 289 TAFFYTLMTCEMLRKKS-GMQIALNDHLKQRREVAKTVFCLVLVFALCWLPLHLSRILKL 347
               Y LM   +LR KS  M     +  +  R + + V  +V VF +CW P+H+  I+K 
Sbjct: 343 ITVCYGLM---ILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHIYVIIKA 399

Query: 348 TLYNQNDPNRCELLSFLLVLDYIGINMASLNSCINPIALYLVSKRFKNCFK 398
            +       +     F + L Y        NSC+NP+    + + FK CF+
Sbjct: 400 LVTIPETTFQTVSWHFCIALGY-------TNSCLNPVLYAFLDENFKRCFR 443


>gi|117940060 opioid receptor, mu 1 isoform MOR-1 [Homo sapiens]
          Length = 400

 Score =  110 bits (275), Expect = 3e-24
 Identities = 80/291 (27%), Positives = 133/291 (45%), Gaps = 21/291 (7%)

Query: 110 LVFVLGIIGNSTLLRIIYKNKCMRNGPNILIASLALGDLLHIVIDIPINVYKLLAEDWPF 169
           +V V+G+ GN  ++ +I +   M+   NI I +LAL D L     +P      L   WPF
Sbjct: 79  IVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADAL-ATSTLPFQSVNYLMGTWPF 137

Query: 170 GAEMCKLVPFIQKASVGITVLSLCALSIDRYRAVASWSRIKGIGVPKWTAVEIVLIWVVS 229
           G  +CK+V  I   ++  ++ +LC +S+DRY AV    +      P+   +  V  W++S
Sbjct: 138 GTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKIINVCNWILS 197

Query: 230 VVLAVPEAIGFDIITMDYKGSY-LRICLLHPVQKTAFMQFYKTAKDWWLFSFYFCLPLAI 288
             + +P  + F   T   +GS    +   HP        +++      +F F F +P+ I
Sbjct: 198 SAIGLP--VMFMATTKYRQGSIDCTLTFSHPT------WYWENLLKICVFIFAFIMPVLI 249

Query: 289 TAFFYTLMTCEMLRKKS-GMQIALNDHLKQRREVAKTVFCLVLVFALCWLPLHLSRILKL 347
               Y LM   +LR KS  M     +  +  R + + V  +V VF +CW P+H+  I+K 
Sbjct: 250 ITVCYGLM---ILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHIYVIIKA 306

Query: 348 TLYNQNDPNRCELLSFLLVLDYIGINMASLNSCINPIALYLVSKRFKNCFK 398
            +       +     F + L Y        NSC+NP+    + + FK CF+
Sbjct: 307 LVTIPETTFQTVSWHFCIALGY-------TNSCLNPVLYAFLDENFKRCFR 350


>gi|223718712 opioid receptor, mu 1 isoform MOR-1B5 [Homo sapiens]
          Length = 420

 Score =  110 bits (275), Expect = 3e-24
 Identities = 80/291 (27%), Positives = 133/291 (45%), Gaps = 21/291 (7%)

Query: 110 LVFVLGIIGNSTLLRIIYKNKCMRNGPNILIASLALGDLLHIVIDIPINVYKLLAEDWPF 169
           +V V+G+ GN  ++ +I +   M+   NI I +LAL D L     +P      L   WPF
Sbjct: 79  IVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADAL-ATSTLPFQSVNYLMGTWPF 137

Query: 170 GAEMCKLVPFIQKASVGITVLSLCALSIDRYRAVASWSRIKGIGVPKWTAVEIVLIWVVS 229
           G  +CK+V  I   ++  ++ +LC +S+DRY AV    +      P+   +  V  W++S
Sbjct: 138 GTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKIINVCNWILS 197

Query: 230 VVLAVPEAIGFDIITMDYKGSY-LRICLLHPVQKTAFMQFYKTAKDWWLFSFYFCLPLAI 288
             + +P  + F   T   +GS    +   HP        +++      +F F F +P+ I
Sbjct: 198 SAIGLP--VMFMATTKYRQGSIDCTLTFSHPT------WYWENLLKICVFIFAFIMPVLI 249

Query: 289 TAFFYTLMTCEMLRKKS-GMQIALNDHLKQRREVAKTVFCLVLVFALCWLPLHLSRILKL 347
               Y LM   +LR KS  M     +  +  R + + V  +V VF +CW P+H+  I+K 
Sbjct: 250 ITVCYGLM---ILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHIYVIIKA 306

Query: 348 TLYNQNDPNRCELLSFLLVLDYIGINMASLNSCINPIALYLVSKRFKNCFK 398
            +       +     F + L Y        NSC+NP+    + + FK CF+
Sbjct: 307 LVTIPETTFQTVSWHFCIALGY-------TNSCLNPVLYAFLDENFKRCFR 350


>gi|223718719 opioid receptor, mu 1 isoform MOR-1B2 [Homo sapiens]
          Length = 397

 Score =  110 bits (275), Expect = 3e-24
 Identities = 80/291 (27%), Positives = 133/291 (45%), Gaps = 21/291 (7%)

Query: 110 LVFVLGIIGNSTLLRIIYKNKCMRNGPNILIASLALGDLLHIVIDIPINVYKLLAEDWPF 169
           +V V+G+ GN  ++ +I +   M+   NI I +LAL D L     +P      L   WPF
Sbjct: 79  IVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADAL-ATSTLPFQSVNYLMGTWPF 137

Query: 170 GAEMCKLVPFIQKASVGITVLSLCALSIDRYRAVASWSRIKGIGVPKWTAVEIVLIWVVS 229
           G  +CK+V  I   ++  ++ +LC +S+DRY AV    +      P+   +  V  W++S
Sbjct: 138 GTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKIINVCNWILS 197

Query: 230 VVLAVPEAIGFDIITMDYKGSY-LRICLLHPVQKTAFMQFYKTAKDWWLFSFYFCLPLAI 288
             + +P  + F   T   +GS    +   HP        +++      +F F F +P+ I
Sbjct: 198 SAIGLP--VMFMATTKYRQGSIDCTLTFSHPT------WYWENLLKICVFIFAFIMPVLI 249

Query: 289 TAFFYTLMTCEMLRKKS-GMQIALNDHLKQRREVAKTVFCLVLVFALCWLPLHLSRILKL 347
               Y LM   +LR KS  M     +  +  R + + V  +V VF +CW P+H+  I+K 
Sbjct: 250 ITVCYGLM---ILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHIYVIIKA 306

Query: 348 TLYNQNDPNRCELLSFLLVLDYIGINMASLNSCINPIALYLVSKRFKNCFK 398
            +       +     F + L Y        NSC+NP+    + + FK CF+
Sbjct: 307 LVTIPETTFQTVSWHFCIALGY-------TNSCLNPVLYAFLDENFKRCFR 350


>gi|223718077 opioid receptor, mu 1 isoform MOR-1B3 [Homo sapiens]
          Length = 403

 Score =  110 bits (275), Expect = 3e-24
 Identities = 80/291 (27%), Positives = 133/291 (45%), Gaps = 21/291 (7%)

Query: 110 LVFVLGIIGNSTLLRIIYKNKCMRNGPNILIASLALGDLLHIVIDIPINVYKLLAEDWPF 169
           +V V+G+ GN  ++ +I +   M+   NI I +LAL D L     +P      L   WPF
Sbjct: 79  IVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADAL-ATSTLPFQSVNYLMGTWPF 137

Query: 170 GAEMCKLVPFIQKASVGITVLSLCALSIDRYRAVASWSRIKGIGVPKWTAVEIVLIWVVS 229
           G  +CK+V  I   ++  ++ +LC +S+DRY AV    +      P+   +  V  W++S
Sbjct: 138 GTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKIINVCNWILS 197

Query: 230 VVLAVPEAIGFDIITMDYKGSY-LRICLLHPVQKTAFMQFYKTAKDWWLFSFYFCLPLAI 288
             + +P  + F   T   +GS    +   HP        +++      +F F F +P+ I
Sbjct: 198 SAIGLP--VMFMATTKYRQGSIDCTLTFSHPT------WYWENLLKICVFIFAFIMPVLI 249

Query: 289 TAFFYTLMTCEMLRKKS-GMQIALNDHLKQRREVAKTVFCLVLVFALCWLPLHLSRILKL 347
               Y LM   +LR KS  M     +  +  R + + V  +V VF +CW P+H+  I+K 
Sbjct: 250 ITVCYGLM---ILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHIYVIIKA 306

Query: 348 TLYNQNDPNRCELLSFLLVLDYIGINMASLNSCINPIALYLVSKRFKNCFK 398
            +       +     F + L Y        NSC+NP+    + + FK CF+
Sbjct: 307 LVTIPETTFQTVSWHFCIALGY-------TNSCLNPVLYAFLDENFKRCFR 350


>gi|223718716 opioid receptor, mu 1 isoform MOR-1B1 [Homo sapiens]
          Length = 406

 Score =  110 bits (275), Expect = 3e-24
 Identities = 80/291 (27%), Positives = 133/291 (45%), Gaps = 21/291 (7%)

Query: 110 LVFVLGIIGNSTLLRIIYKNKCMRNGPNILIASLALGDLLHIVIDIPINVYKLLAEDWPF 169
           +V V+G+ GN  ++ +I +   M+   NI I +LAL D L     +P      L   WPF
Sbjct: 79  IVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADAL-ATSTLPFQSVNYLMGTWPF 137

Query: 170 GAEMCKLVPFIQKASVGITVLSLCALSIDRYRAVASWSRIKGIGVPKWTAVEIVLIWVVS 229
           G  +CK+V  I   ++  ++ +LC +S+DRY AV    +      P+   +  V  W++S
Sbjct: 138 GTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKIINVCNWILS 197

Query: 230 VVLAVPEAIGFDIITMDYKGSY-LRICLLHPVQKTAFMQFYKTAKDWWLFSFYFCLPLAI 288
             + +P  + F   T   +GS    +   HP        +++      +F F F +P+ I
Sbjct: 198 SAIGLP--VMFMATTKYRQGSIDCTLTFSHPT------WYWENLLKICVFIFAFIMPVLI 249

Query: 289 TAFFYTLMTCEMLRKKS-GMQIALNDHLKQRREVAKTVFCLVLVFALCWLPLHLSRILKL 347
               Y LM   +LR KS  M     +  +  R + + V  +V VF +CW P+H+  I+K 
Sbjct: 250 ITVCYGLM---ILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHIYVIIKA 306

Query: 348 TLYNQNDPNRCELLSFLLVLDYIGINMASLNSCINPIALYLVSKRFKNCFK 398
            +       +     F + L Y        NSC+NP+    + + FK CF+
Sbjct: 307 LVTIPETTFQTVSWHFCIALGY-------TNSCLNPVLYAFLDENFKRCFR 350


>gi|117940058 opioid receptor, mu 1 isoform MOR-1A [Homo sapiens]
          Length = 392

 Score =  110 bits (275), Expect = 3e-24
 Identities = 80/291 (27%), Positives = 133/291 (45%), Gaps = 21/291 (7%)

Query: 110 LVFVLGIIGNSTLLRIIYKNKCMRNGPNILIASLALGDLLHIVIDIPINVYKLLAEDWPF 169
           +V V+G+ GN  ++ +I +   M+   NI I +LAL D L     +P      L   WPF
Sbjct: 79  IVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADAL-ATSTLPFQSVNYLMGTWPF 137

Query: 170 GAEMCKLVPFIQKASVGITVLSLCALSIDRYRAVASWSRIKGIGVPKWTAVEIVLIWVVS 229
           G  +CK+V  I   ++  ++ +LC +S+DRY AV    +      P+   +  V  W++S
Sbjct: 138 GTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKIINVCNWILS 197

Query: 230 VVLAVPEAIGFDIITMDYKGSY-LRICLLHPVQKTAFMQFYKTAKDWWLFSFYFCLPLAI 288
             + +P  + F   T   +GS    +   HP        +++      +F F F +P+ I
Sbjct: 198 SAIGLP--VMFMATTKYRQGSIDCTLTFSHPT------WYWENLLKICVFIFAFIMPVLI 249

Query: 289 TAFFYTLMTCEMLRKKS-GMQIALNDHLKQRREVAKTVFCLVLVFALCWLPLHLSRILKL 347
               Y LM   +LR KS  M     +  +  R + + V  +V VF +CW P+H+  I+K 
Sbjct: 250 ITVCYGLM---ILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHIYVIIKA 306

Query: 348 TLYNQNDPNRCELLSFLLVLDYIGINMASLNSCINPIALYLVSKRFKNCFK 398
            +       +     F + L Y        NSC+NP+    + + FK CF+
Sbjct: 307 LVTIPETTFQTVSWHFCIALGY-------TNSCLNPVLYAFLDENFKRCFR 350


>gi|223717969 opioid receptor, mu 1 isoform MOR-1B4 [Homo sapiens]
          Length = 389

 Score =  110 bits (275), Expect = 3e-24
 Identities = 80/291 (27%), Positives = 133/291 (45%), Gaps = 21/291 (7%)

Query: 110 LVFVLGIIGNSTLLRIIYKNKCMRNGPNILIASLALGDLLHIVIDIPINVYKLLAEDWPF 169
           +V V+G+ GN  ++ +I +   M+   NI I +LAL D L     +P      L   WPF
Sbjct: 79  IVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADAL-ATSTLPFQSVNYLMGTWPF 137

Query: 170 GAEMCKLVPFIQKASVGITVLSLCALSIDRYRAVASWSRIKGIGVPKWTAVEIVLIWVVS 229
           G  +CK+V  I   ++  ++ +LC +S+DRY AV    +      P+   +  V  W++S
Sbjct: 138 GTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKIINVCNWILS 197

Query: 230 VVLAVPEAIGFDIITMDYKGSY-LRICLLHPVQKTAFMQFYKTAKDWWLFSFYFCLPLAI 288
             + +P  + F   T   +GS    +   HP        +++      +F F F +P+ I
Sbjct: 198 SAIGLP--VMFMATTKYRQGSIDCTLTFSHPT------WYWENLLKICVFIFAFIMPVLI 249

Query: 289 TAFFYTLMTCEMLRKKS-GMQIALNDHLKQRREVAKTVFCLVLVFALCWLPLHLSRILKL 347
               Y LM   +LR KS  M     +  +  R + + V  +V VF +CW P+H+  I+K 
Sbjct: 250 ITVCYGLM---ILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHIYVIIKA 306

Query: 348 TLYNQNDPNRCELLSFLLVLDYIGINMASLNSCINPIALYLVSKRFKNCFK 398
            +       +     F + L Y        NSC+NP+    + + FK CF+
Sbjct: 307 LVTIPETTFQTVSWHFCIALGY-------TNSCLNPVLYAFLDENFKRCFR 350


>gi|117940055 opioid receptor, mu 1 isoform MOR-1O [Homo sapiens]
          Length = 418

 Score =  110 bits (275), Expect = 3e-24
 Identities = 80/291 (27%), Positives = 133/291 (45%), Gaps = 21/291 (7%)

Query: 110 LVFVLGIIGNSTLLRIIYKNKCMRNGPNILIASLALGDLLHIVIDIPINVYKLLAEDWPF 169
           +V V+G+ GN  ++ +I +   M+   NI I +LAL D L     +P      L   WPF
Sbjct: 79  IVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADAL-ATSTLPFQSVNYLMGTWPF 137

Query: 170 GAEMCKLVPFIQKASVGITVLSLCALSIDRYRAVASWSRIKGIGVPKWTAVEIVLIWVVS 229
           G  +CK+V  I   ++  ++ +LC +S+DRY AV    +      P+   +  V  W++S
Sbjct: 138 GTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKIINVCNWILS 197

Query: 230 VVLAVPEAIGFDIITMDYKGSY-LRICLLHPVQKTAFMQFYKTAKDWWLFSFYFCLPLAI 288
             + +P  + F   T   +GS    +   HP        +++      +F F F +P+ I
Sbjct: 198 SAIGLP--VMFMATTKYRQGSIDCTLTFSHPT------WYWENLLKICVFIFAFIMPVLI 249

Query: 289 TAFFYTLMTCEMLRKKS-GMQIALNDHLKQRREVAKTVFCLVLVFALCWLPLHLSRILKL 347
               Y LM   +LR KS  M     +  +  R + + V  +V VF +CW P+H+  I+K 
Sbjct: 250 ITVCYGLM---ILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHIYVIIKA 306

Query: 348 TLYNQNDPNRCELLSFLLVLDYIGINMASLNSCINPIALYLVSKRFKNCFK 398
            +       +     F + L Y        NSC+NP+    + + FK CF+
Sbjct: 307 LVTIPETTFQTVSWHFCIALGY-------TNSCLNPVLYAFLDENFKRCFR 350


>gi|117940054 opioid receptor, mu 1 isoform MOR-1X [Homo sapiens]
          Length = 446

 Score =  110 bits (275), Expect = 3e-24
 Identities = 80/291 (27%), Positives = 133/291 (45%), Gaps = 21/291 (7%)

Query: 110 LVFVLGIIGNSTLLRIIYKNKCMRNGPNILIASLALGDLLHIVIDIPINVYKLLAEDWPF 169
           +V V+G+ GN  ++ +I +   M+   NI I +LAL D L     +P      L   WPF
Sbjct: 79  IVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADAL-ATSTLPFQSVNYLMGTWPF 137

Query: 170 GAEMCKLVPFIQKASVGITVLSLCALSIDRYRAVASWSRIKGIGVPKWTAVEIVLIWVVS 229
           G  +CK+V  I   ++  ++ +LC +S+DRY AV    +      P+   +  V  W++S
Sbjct: 138 GTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKIINVCNWILS 197

Query: 230 VVLAVPEAIGFDIITMDYKGSY-LRICLLHPVQKTAFMQFYKTAKDWWLFSFYFCLPLAI 288
             + +P  + F   T   +GS    +   HP        +++      +F F F +P+ I
Sbjct: 198 SAIGLP--VMFMATTKYRQGSIDCTLTFSHPT------WYWENLLKICVFIFAFIMPVLI 249

Query: 289 TAFFYTLMTCEMLRKKS-GMQIALNDHLKQRREVAKTVFCLVLVFALCWLPLHLSRILKL 347
               Y LM   +LR KS  M     +  +  R + + V  +V VF +CW P+H+  I+K 
Sbjct: 250 ITVCYGLM---ILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHIYVIIKA 306

Query: 348 TLYNQNDPNRCELLSFLLVLDYIGINMASLNSCINPIALYLVSKRFKNCFK 398
            +       +     F + L Y        NSC+NP+    + + FK CF+
Sbjct: 307 LVTIPETTFQTVSWHFCIALGY-------TNSCLNPVLYAFLDENFKRCFR 350


>gi|157738685 G protein-coupled receptor 103 [Homo sapiens]
          Length = 431

 Score =  109 bits (272), Expect = 6e-24
 Identities = 74/313 (23%), Positives = 151/313 (48%), Gaps = 24/313 (7%)

Query: 95  EIKETFKYINTVVSCLVFVLGIIGNSTLLRIIYKNKCMRNGPNILIASLALGDLLHIVID 154
           E+    K    +   L+F L + GN+ +  ++ ++K MR   NI I SLAL DLL     
Sbjct: 39  ELPGRAKLALVLTGVLIFALALFGNALVFYVVTRSKAMRTVTNIFICSLALSDLLITFFC 98

Query: 155 IPINVYKLLAEDWPFGAEMCKLVPFIQKASVGITVLSLCALSIDRYRAVASWSRIKGIGV 214
           IP+ + + ++++W  GA +CK+VPF+Q  +V   +L++  ++++R++ +    ++K    
Sbjct: 99  IPVTMLQNISDNWLGGAFICKMVPFVQSTAVVTEILTMTCIAVERHQGLVHPFKMKWQYT 158

Query: 215 PKWTAVEIVLIWVVSVVLAVPEAIGFDIITMDYKGSYL----RICLLHPVQKTAFMQFYK 270
            +     + ++W+V+V++  P    + +  ++ K  +L     IC L         + Y 
Sbjct: 159 NRRAFTMLGVVWLVAVIVGSPM---WHVQQLEIKYDFLYEKEHICCLEEWTSPVHQKIYT 215

Query: 271 TAKDWWLFSFYFCLPLAITAFFYTLMTCEM-LRKKSGMQIALND-HLKQRREVAK----- 323
           T    ++    F LPL +    Y+ +  E+ ++K+ G    L   H K+  ++A+     
Sbjct: 216 T----FILVILFLLPLMVMLILYSKIGYELWIKKRVGDGSVLRTIHGKEMSKIARKKKRA 271

Query: 324 --TVFCLVLVFALCWLPLHLSRILKLTLYNQNDPNRCELLSFLLVLDYIGINMASLNSCI 381
              +  +V +FA+CW P H+  ++      + + +   +     ++  IG +    NS  
Sbjct: 272 VIMMVTVVALFAVCWAPFHVVHMMIEYSNFEKEYDDVTIKMIFAIVQIIGFS----NSIC 327

Query: 382 NPIALYLVSKRFK 394
           NPI    +++ FK
Sbjct: 328 NPIVYAFMNENFK 340


>gi|4758474 G protein-coupled receptor 10 [Homo sapiens]
          Length = 370

 Score =  108 bits (271), Expect = 7e-24
 Identities = 96/359 (26%), Positives = 162/359 (45%), Gaps = 48/359 (13%)

Query: 30  GFPPDRATPLLQTAEIMTPPTKTLWPKGSNASLARSLAPAEVPKGDRTAGSPPRTISPPP 89
           G PP   TP  Q+AE              N S+A + APA  P                 
Sbjct: 17  GLPPAVTTPANQSAEA----------SAGNGSVAGADAPAVTPFQS-------------- 52

Query: 90  CQGPIEIKETFKYINTVVSCLVFVLGIIGNSTLLRIIYKNKCMRNGPNILIASLALGDLL 149
               +++    K +  ++  +V V+G++GN  L+ +I + + + N  N LI +LAL D+L
Sbjct: 53  ----LQLVHQLKGLIVLLYSVVVVVGLVGNCLLVLVIARVRRLHNVTNFLIGNLALSDVL 108

Query: 150 HIVIDIPINV-YKLLAEDWPFGAEMCKLVPFIQKASVGITVLSLCALSIDRYRAVASWSR 208
                +P+ + Y      W FG  +C LV F+Q  +V ++V +L  +++DRY  +    R
Sbjct: 109 MCTACVPLTLAYAFEPRGWVFGGGLCHLVFFLQPVTVYVSVFTLTTIAVDRYVVLVHPLR 168

Query: 209 IKGIGVPKWTAVEIVLIWVVSVVLAVPEAIGFDIITMDYKGSYLRICLLHPVQKTAFMQF 268
            + I + + +A  ++ IW +S VLA+P A+      ++ K   +R+C      +    Q 
Sbjct: 169 -RRISL-RLSAYAVLAIWALSAVLALPAAV--HTYHVELKPHDVRLCEEFWGSQERQRQL 224

Query: 269 YKTAKDWWLFSFYFCLPLAITAFFYTLMTCEMLRKKSGMQIALNDHLKQRREVAKTVFCL 328
           Y     W L    + LPL +    Y  ++ + LR +              R   +  FCL
Sbjct: 225 YA----WGLLLVTYLLPLLVILLSYVRVSVK-LRNRVVPGCVTQSQADWDRARRRRTFCL 279

Query: 329 ----VLVFALCWLPLHLSRILKLTLYNQNDPNRCELLSFLLVLDYIGINMASLNSCINP 383
               V+VFA+CWLPLH+  +L+       DP+  +  +F LV   +   +A  ++C NP
Sbjct: 280 LVVVVVVFAVCWLPLHVFNLLR-----DLDPHAIDPYAFGLV-QLLCHWLAMSSACYNP 332


>gi|4505513 opiate receptor-like 1 [Homo sapiens]
          Length = 370

 Score =  108 bits (269), Expect = 1e-23
 Identities = 80/297 (26%), Positives = 135/297 (45%), Gaps = 35/297 (11%)

Query: 111 VFVLGIIGNSTLLRIIYKNKCMRNGPNILIASLALGDLLHIVIDIPINVYKLLAEDWPFG 170
           V V G++GN  ++ +I ++  M+   NI I +LAL D L +++ +P     +L   WPFG
Sbjct: 61  VCVGGLLGNCLVMYVILRHTKMKTATNIYIFNLALADTL-VLLTLPFQGTDILLGFWPFG 119

Query: 171 AEMCKLVPFIQKASVGITVLSLCALSIDRYRAVASWSRIKGIGVPKWTAVEIVLIWVVSV 230
             +CK V  I   ++  +  +L A+S+DRY A+    R   +          V IW ++ 
Sbjct: 120 NALCKTVIAIDYYNMFTSTFTLTAMSVDRYVAICHPIRALDVRTSSKAQAVNVAIWALAS 179

Query: 231 VLAVPEAIGFDIITMDYKGSYLRICLLHPVQKTAFMQFYKTAKDWW-------LFSFYFC 283
           V+ VP AI       D +      CL+             T +D+W       +F F F 
Sbjct: 180 VVGVPVAIMGSAQVEDEEIE----CLVE----------IPTPQDYWGPVFAICIFLFSFI 225

Query: 284 LPLAITAFFYTLMTCEMLRKKSGMQIALNDHLKQR--REVAKTVFCLVLVFALCWLPLHL 341
           +P+ + +  Y+L    M+R+  G+++      K R  R + + V  +V VF  CW P+ +
Sbjct: 226 VPVLVISVCYSL----MIRRLRGVRLLSGSREKDRNLRRITRLVLVVVAVFVGCWTPVQV 281

Query: 342 SRILKLTLYNQNDPNRCELLSFLLVLDYIGINMASLNSCINPIALYLVSKRFKNCFK 398
             + +      +      +L F   L Y+       NSC+NPI    + + FK CF+
Sbjct: 282 FVLAQGLGVQPSSETAVAILRFCTALGYV-------NSCLNPILYAFLDENFKACFR 331


>gi|33286424 opiate receptor-like 1 [Homo sapiens]
          Length = 370

 Score =  108 bits (269), Expect = 1e-23
 Identities = 80/297 (26%), Positives = 135/297 (45%), Gaps = 35/297 (11%)

Query: 111 VFVLGIIGNSTLLRIIYKNKCMRNGPNILIASLALGDLLHIVIDIPINVYKLLAEDWPFG 170
           V V G++GN  ++ +I ++  M+   NI I +LAL D L +++ +P     +L   WPFG
Sbjct: 61  VCVGGLLGNCLVMYVILRHTKMKTATNIYIFNLALADTL-VLLTLPFQGTDILLGFWPFG 119

Query: 171 AEMCKLVPFIQKASVGITVLSLCALSIDRYRAVASWSRIKGIGVPKWTAVEIVLIWVVSV 230
             +CK V  I   ++  +  +L A+S+DRY A+    R   +          V IW ++ 
Sbjct: 120 NALCKTVIAIDYYNMFTSTFTLTAMSVDRYVAICHPIRALDVRTSSKAQAVNVAIWALAS 179

Query: 231 VLAVPEAIGFDIITMDYKGSYLRICLLHPVQKTAFMQFYKTAKDWW-------LFSFYFC 283
           V+ VP AI       D +      CL+             T +D+W       +F F F 
Sbjct: 180 VVGVPVAIMGSAQVEDEEIE----CLVE----------IPTPQDYWGPVFAICIFLFSFI 225

Query: 284 LPLAITAFFYTLMTCEMLRKKSGMQIALNDHLKQR--REVAKTVFCLVLVFALCWLPLHL 341
           +P+ + +  Y+L    M+R+  G+++      K R  R + + V  +V VF  CW P+ +
Sbjct: 226 VPVLVISVCYSL----MIRRLRGVRLLSGSREKDRNLRRITRLVLVVVAVFVGCWTPVQV 281

Query: 342 SRILKLTLYNQNDPNRCELLSFLLVLDYIGINMASLNSCINPIALYLVSKRFKNCFK 398
             + +      +      +L F   L Y+       NSC+NPI    + + FK CF+
Sbjct: 282 FVLAQGLGVQPSSETAVAILRFCTALGYV-------NSCLNPILYAFLDENFKACFR 331


>gi|149944554 somatostatin receptor 4 [Homo sapiens]
          Length = 388

 Score =  107 bits (268), Expect = 2e-23
 Identities = 83/350 (23%), Positives = 152/350 (43%), Gaps = 46/350 (13%)

Query: 52  TLWPKGSNASLARSLAPAEVPKGDRTAGSPPRTISPPPCQGPIEIKETFKYINTVVSCLV 111
           T WP  +NAS A    PAE  +                  GP + +         +  LV
Sbjct: 17  TAWPSAANASSA----PAEAEEA---------------VAGPGDARAAGMVAIQCIYALV 57

Query: 112 FVLGIIGNSTLLRIIYKNKCMRNGPNILIASLALGDLLHIVIDIPINVYKLLAEDWPFGA 171
            ++G++GN+ ++ +I +   M+   NI + +LA+ D L  ++ +P          WPFG+
Sbjct: 58  CLVGLVGNALVIFVILRYAKMKTATNIYLLNLAVADEL-FMLSVPFVASSAALRHWPFGS 116

Query: 172 EMCKLVPFIQKASVGITVLSLCALSIDRYRAVASWSRIKGIGVPKWTAVEIVLIWVVSVV 231
            +C+ V  +   ++  +V  L  LS+DRY AV    R      P    +  + +W+ S++
Sbjct: 117 VLCRAVLSVDGLNMFTSVFCLTVLSVDRYVAVVHPLRAATYRRPSVAKLINLGVWLASLL 176

Query: 232 LAVPEAIGFDIITMDYKGSYLRICLL---HPVQKTAFMQFYKTAKDWWLFSFYFCLPLAI 288
           + +P AI  D  T   +G     C L   HP     F+ +         F   F LP+  
Sbjct: 177 VTLPIAIFAD--TRPARGGQAVACNLQWPHPAWSAVFVVY--------TFLLGFLLPVLA 226

Query: 289 TAFFYTLMTCEMLRKKSGMQIALNDHLKQRREVAKTVFCLVLVFALCWLPLHLSRILKLT 348
               Y L+  +M  +   ++       +  +++ + V  +V+VF LCW+P ++ ++L L 
Sbjct: 227 IGLCYLLIVGKM--RAVALRAGWQQRRRSEKKITRLVLMVVVVFVLCWMPFYVVQLLNLF 284

Query: 349 LYNQNDPNRCELLSFLLVLDYIGINMASLNSCINPIALYLVSKRFKNCFK 398
                      + S    ++++ + ++  NSC NPI    +S  F+  F+
Sbjct: 285 -----------VTSLDATVNHVSLILSYANSCANPILYGFLSDNFRRFFQ 323


>gi|167000885 galanin receptor 1 [Homo sapiens]
          Length = 349

 Score =  107 bits (268), Expect = 2e-23
 Identities = 86/338 (25%), Positives = 156/338 (46%), Gaps = 33/338 (9%)

Query: 70  EVPKGDRTAGSPPRTISPPPCQGPIEIKETFKYINTVVSCLVFVLGIIGNSTLLRIIYKN 129
           E+  G+ + G+      P P  GP+       ++  VV  L+F LG++GNS ++ ++ ++
Sbjct: 2   ELAVGNLSEGNASWPEPPAPEPGPLFGIGVENFVTLVVFGLIFALGVLGNSLVITVLARS 61

Query: 130 KC--MRNGPNILIASLALGDLLHIVIDIPINVYKLLAEDWPFGAEMCKLVPFIQKASVGI 187
           K    R+  N+ I +L++ DL +++  IP          W  GA +CK + +    S+ +
Sbjct: 62  KPGKPRSTTNLFILNLSIADLAYLLFCIPFQATVYALPTWVLGAFICKFIHYFFTVSMLV 121

Query: 188 TVLSLCALSIDRYRAVASWSRIKGIGVPKWTAVEIVLIWVVSVVLAVPEAIGFDIITMDY 247
           ++ +L A+S+DRY A+    R   + V +   + +  IW +S+ +A P A         +
Sbjct: 122 SIFTLAAMSVDRYVAIVHSRRSSSLRVSRNALLGVGCIWALSIAMASPVAY--------H 173

Query: 248 KGSYLRICLLHP---VQKTAFMQF----YKTAKDWWLFSFYFCLPLAITAFFYTLMTCEM 300
           +G      L HP    Q   + Q+    +K A     F F + LPL +  F Y  +   +
Sbjct: 174 QG------LFHPRASNQTFCWEQWPDPRHKKAYVVCTFVFGYLLPLLLICFCYAKVLNHL 227

Query: 301 LRKKSGMQIALNDHLKQRREVAKTVFCLVLVFALCWLPLHLSRILKLTLYNQNDPNRCEL 360
            +K   M          +++ A+TV  +V+VF + WLP H+     + L+ +        
Sbjct: 228 HKKLKNMS---KKSEASKKKTAQTVLVVVVVFGISWLPHHI-----IHLWAEFGVFPLTP 279

Query: 361 LSFLLVLDYIGINMASLNSCINPIALYLVSKRFKNCFK 398
            SFL  +      +A  NS +NPI    +S+ F+  +K
Sbjct: 280 ASFLFRI--TAHCLAYSNSSVNPIIYAFLSENFRKAYK 315


>gi|4504683 interleukin 8 receptor beta [Homo sapiens]
          Length = 360

 Score =  106 bits (265), Expect = 4e-23
 Identities = 82/323 (25%), Positives = 148/323 (45%), Gaps = 37/323 (11%)

Query: 81  PPRTISPPPCQGPIEIKETFKYINTVVSCLVFVLGIIGNSTLLRIIYKNKCMRNGPNILI 140
           PP  +   PC+   E  E  KY   ++  LVF+L ++GNS ++ +I  ++  R+  ++ +
Sbjct: 30  PPFLLDAAPCEP--ESLEINKYFVVIIYALVFLLSLLGNSLVMLVILYSRVGRSVTDVYL 87

Query: 141 ASLALGDLLHIVIDIPINVYKLLAEDWPFGAEMCKLVPFIQKASVGITVLSLCALSIDRY 200
            +LAL DLL   + +PI     +   W FG  +CK+V  +++ +    +L L  +S+DRY
Sbjct: 88  LNLALADLL-FALTLPIWAASKV-NGWIFGTFLCKVVSLLKEVNFYSGILLLACISVDRY 145

Query: 201 RAVASWSRIKGIGVPKWTAVEIVL-IWVVSVVLAVPEAIGFDIITMDYKGSYLRICLLHP 259
            A+   +R   +   ++    I L IW +S++LA+P  +            + R      
Sbjct: 146 LAIVHATRT--LTQKRYLVKFICLSIWGLSLLLALPVLL------------FRRTVYSSN 191

Query: 260 VQKTAFMQFYKTAKDWWLF------SFYFCLPLAITAFFYTLMTCEMLRKKSGMQIALND 313
           V    +        +W +       SF F +PL I  F Y             ++     
Sbjct: 192 VSPACYEDMGNNTANWRMLLRILPQSFGFIVPLLIMLFCYGFT----------LRTLFKA 241

Query: 314 HLKQRREVAKTVFCLVLVFALCWLPLHLSRILKLTLYNQNDPNRCELLSFL-LVLDYIGI 372
           H+ Q+    + +F +VL+F LCWLP +L  +    +  Q     CE  + +   LD   I
Sbjct: 242 HMGQKHRAMRVIFAVVLIFLLCWLPYNLVLLADTLMRTQVIQETCERRNHIDRALDATEI 301

Query: 373 NMASLNSCINPIALYLVSKRFKN 395
            +  L+SC+NP+    + ++F++
Sbjct: 302 -LGILHSCLNPLIYAFIGQKFRH 323


>gi|222080109 orexin receptor 2 [Homo sapiens]
          Length = 444

 Score =  105 bits (261), Expect = 1e-22
 Identities = 82/325 (25%), Positives = 147/325 (45%), Gaps = 45/325 (13%)

Query: 110 LVFVLGIIGNSTLLRIIYKNKCMRNGPNILIASLALGDLLHIVIDIPINVYKLLAEDWPF 169
           +VFV+ +IGN  +   ++KN  MR   N  I +L+L D+L  +  +P  +   + E W F
Sbjct: 63  IVFVVALIGNVLVCVAVWKNHHMRTVTNYFIVNLSLADVLVTITCLPATLVVDITETWFF 122

Query: 170 GAEMCKLVPFIQKASVGITVLSLCALSIDRYRAVASWSRIKGIGVPKWTAVEIVLIWVVS 229
           G  +CK++P++Q  SV ++VL+L  +++DR+ A+      K     K     IV+IW+VS
Sbjct: 123 GQSLCKVIPYLQTVSVSVSVLTLSCIALDRWYAICHPLMFK--STAKRARNSIVIIWIVS 180

Query: 230 VVLAVPEAIGFDIITMDYKGSYLRICLLHPVQKTAFMQFYKTAKDWWLFSFYFCLPLAIT 289
            ++ +P+AI  +  T+ + G   +  L     +    + Y        F   +  PL + 
Sbjct: 181 CIIMIPQAIVMECSTV-FPGLANKTTLFTVCDERWGGEIYPKMYHICFFLVTYMAPLCLM 239

Query: 290 AFFYTLM-----------TCEMLRKK-----------------SGMQIALNDHLKQ---R 318
              Y  +           T  ++++K                      A+   +KQ   R
Sbjct: 240 VLAYLQIFRKLWCRQIPGTSSVVQRKWKPLQPVSQPRGPGQPTKSRMSAVAAEIKQIRAR 299

Query: 319 REVAKTVFCLVLVFALCWLPLHLSRILK----LTLYNQNDPNRCELLSFLLVLDYIGINM 374
           R+ A+ +  ++LVFA+C+LP+ +  +LK    +  + ++        +F   L Y     
Sbjct: 300 RKTARMLMIVLLVFAICYLPISILNVLKRVFGMFAHTEDRETVYAWFTFSHWLVY----- 354

Query: 375 ASLNSCINPIALYLVSKRFKNCFKA 399
              NS  NPI    +S +F+  FKA
Sbjct: 355 --ANSAANPIIYNFLSGKFREEFKA 377


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.326    0.140    0.447 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 17,638,892
Number of Sequences: 37866
Number of extensions: 798233
Number of successful extensions: 4532
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 352
Number of HSP's successfully gapped in prelim test: 189
Number of HSP's that attempted gapping in prelim test: 3287
Number of HSP's gapped (non-prelim): 810
length of query: 436
length of database: 18,247,518
effective HSP length: 105
effective length of query: 331
effective length of database: 14,271,588
effective search space: 4723895628
effective search space used: 4723895628
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 63 (28.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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