Guide to the Human Genome
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Search of human proteins with 4503305

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|4503305 defensin, alpha 6 preproprotein [Homo sapiens]
         (100 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|4503305 defensin, alpha 6 preproprotein [Homo sapiens]             204   1e-53
gi|4503303 defensin, alpha 4 preproprotein [Homo sapiens]              91   2e-19
gi|10337585 defensin, alpha 5 preproprotein [Homo sapiens]             81   2e-16
gi|4758146 defensin, alpha 1 preproprotein [Homo sapiens]              75   1e-14
gi|124248516 alpha-defensin 1 [Homo sapiens]                           75   1e-14
gi|4885179 defensin, alpha 3 preproprotein [Homo sapiens]              74   2e-14
gi|103485139 defensin, beta 104A precursor [Homo sapiens]              28   1.6  
gi|103485137 defensin, beta 104B precursor [Homo sapiens]              28   1.6  
gi|157738667 FYVE and coiled-coil domain containing 1 [Homo sapi...    26   7.8  
gi|144953895 nidogen 2 precursor [Homo sapiens]                        26   7.8  
gi|148727255 microtubule associated serine/threonine kinase fami...    26   7.8  

>gi|4503305 defensin, alpha 6 preproprotein [Homo sapiens]
          Length = 100

 Score =  204 bits (519), Expect = 1e-53
 Identities = 100/100 (100%), Positives = 100/100 (100%)

Query: 1   MRTLTILTAVLLVALQAKAEPLQAEDDPLQAKAYEADAQEQRGANDQDFAVSFAEDASSS 60
           MRTLTILTAVLLVALQAKAEPLQAEDDPLQAKAYEADAQEQRGANDQDFAVSFAEDASSS
Sbjct: 1   MRTLTILTAVLLVALQAKAEPLQAEDDPLQAKAYEADAQEQRGANDQDFAVSFAEDASSS 60

Query: 61  LRALGSTRAFTCHCRRSCYSTEYSYGTCTVMGINHRFCCL 100
           LRALGSTRAFTCHCRRSCYSTEYSYGTCTVMGINHRFCCL
Sbjct: 61  LRALGSTRAFTCHCRRSCYSTEYSYGTCTVMGINHRFCCL 100


>gi|4503303 defensin, alpha 4 preproprotein [Homo sapiens]
          Length = 97

 Score = 90.9 bits (224), Expect = 2e-19
 Identities = 48/100 (48%), Positives = 60/100 (60%), Gaps = 8/100 (8%)

Query: 1  MRTLTILTAVLLVALQAKAEPLQAEDDPLQAKAYEADAQEQRGANDQDFAVSFAEDASSS 60
          MR + +L A+LLVALQ +A PLQA  D       EA  QEQRG  DQD ++SFA D SS+
Sbjct: 1  MRIIALLAAILLVALQVRAGPLQARGD-------EAPGQEQRGPEDQDISISFAWDKSSA 53

Query: 61 LRALGSTRAFTCHCRR-SCYSTEYSYGTCTVMGINHRFCC 99
          L+  GSTR   C CR   C  TE   G C + G++  +CC
Sbjct: 54 LQVSGSTRGMVCSCRLVFCRRTELRVGNCLIGGVSFTYCC 93


>gi|10337585 defensin, alpha 5 preproprotein [Homo sapiens]
          Length = 94

 Score = 81.3 bits (199), Expect = 2e-16
 Identities = 46/100 (46%), Positives = 59/100 (59%), Gaps = 8/100 (8%)

Query: 1  MRTLTILTAVLLVALQAKAEPLQAEDDPLQAKAYEADAQEQRGANDQDFAVSFAEDASSS 60
          MRT+ IL A+LLVALQA+AE LQ   D       EA  Q+Q G ++QD A+SFA +  S+
Sbjct: 1  MRTIAILAAILLVALQAQAESLQERAD-------EATTQKQSGEDNQDLAISFAGNGLSA 53

Query: 61 LRALGSTRAFTCHCRRS-CYSTEYSYGTCTVMGINHRFCC 99
          LR  GS    TC+CR   C + E   G C + G  +R CC
Sbjct: 54 LRTSGSQARATCYCRTGRCATRESLSGVCEISGRLYRLCC 93


>gi|4758146 defensin, alpha 1 preproprotein [Homo sapiens]
          Length = 94

 Score = 74.7 bits (182), Expect = 1e-14
 Identities = 46/100 (46%), Positives = 57/100 (57%), Gaps = 7/100 (7%)

Query: 1  MRTLTILTAVLLVALQAKAEPLQAEDDPLQAKAYEADAQEQRGANDQDFAVSFAEDASSS 60
          MRTL IL A+LLVALQA+AEPLQA  D + A      A EQ  A+  +  VS A D S +
Sbjct: 1  MRTLAILAAILLVALQAQAEPLQARADEVAA------APEQIAADIPEVVVSLAWDESLA 54

Query: 61 LRALGSTRAFTCHCR-RSCYSTEYSYGTCTVMGINHRFCC 99
           +  GS +   C+CR  +C + E  YGTC   G    FCC
Sbjct: 55 PKHPGSRKNMACYCRIPACIAGERRYGTCIYQGRLWAFCC 94


>gi|124248516 alpha-defensin 1 [Homo sapiens]
          Length = 94

 Score = 74.7 bits (182), Expect = 1e-14
 Identities = 46/100 (46%), Positives = 57/100 (57%), Gaps = 7/100 (7%)

Query: 1  MRTLTILTAVLLVALQAKAEPLQAEDDPLQAKAYEADAQEQRGANDQDFAVSFAEDASSS 60
          MRTL IL A+LLVALQA+AEPLQA  D + A      A EQ  A+  +  VS A D S +
Sbjct: 1  MRTLAILAAILLVALQAQAEPLQARADEVAA------APEQIAADIPEVVVSLAWDESLA 54

Query: 61 LRALGSTRAFTCHCR-RSCYSTEYSYGTCTVMGINHRFCC 99
           +  GS +   C+CR  +C + E  YGTC   G    FCC
Sbjct: 55 PKHPGSRKNMACYCRIPACIAGERRYGTCIYQGRLWAFCC 94


>gi|4885179 defensin, alpha 3 preproprotein [Homo sapiens]
          Length = 94

 Score = 74.3 bits (181), Expect = 2e-14
 Identities = 46/100 (46%), Positives = 57/100 (57%), Gaps = 7/100 (7%)

Query: 1  MRTLTILTAVLLVALQAKAEPLQAEDDPLQAKAYEADAQEQRGANDQDFAVSFAEDASSS 60
          MRTL IL A+LLVALQA+AEPLQA  D + A      A EQ  A+  +  VS A D S +
Sbjct: 1  MRTLAILAAILLVALQAQAEPLQARADEVAA------APEQIAADIPEVVVSLAWDESLA 54

Query: 61 LRALGSTRAFTCHCR-RSCYSTEYSYGTCTVMGINHRFCC 99
           +  GS +   C+CR  +C + E  YGTC   G    FCC
Sbjct: 55 PKHPGSRKNMDCYCRIPACIAGERRYGTCIYQGRLWAFCC 94


>gi|103485139 defensin, beta 104A precursor [Homo sapiens]
          Length = 72

 Score = 28.1 bits (61), Expect = 1.6
 Identities = 13/30 (43%), Positives = 14/30 (46%), Gaps = 4/30 (13%)

Query: 71  TCHCRRSCYSTEYSYGTCTVMGINHRFCCL 100
           T  CR+ C S EY  G C     N   CCL
Sbjct: 34  TARCRKKCRSQEYRIGRCP----NTYACCL 59


>gi|103485137 defensin, beta 104B precursor [Homo sapiens]
          Length = 72

 Score = 28.1 bits (61), Expect = 1.6
 Identities = 13/30 (43%), Positives = 14/30 (46%), Gaps = 4/30 (13%)

Query: 71  TCHCRRSCYSTEYSYGTCTVMGINHRFCCL 100
           T  CR+ C S EY  G C     N   CCL
Sbjct: 34  TARCRKKCRSQEYRIGRCP----NTYACCL 59


>gi|157738667 FYVE and coiled-coil domain containing 1 [Homo
           sapiens]
          Length = 1478

 Score = 25.8 bits (55), Expect = 7.8
 Identities = 18/54 (33%), Positives = 25/54 (46%)

Query: 9   AVLLVALQAKAEPLQAEDDPLQAKAYEADAQEQRGANDQDFAVSFAEDASSSLR 62
           A  L   QA+ E  Q E   LQA+  +  A+ +   +DQD   S    A + LR
Sbjct: 768 AAQLALSQAQLEVHQGEVQRLQAQVVDLQAKMRAALDDQDKVQSQLSMAEAVLR 821


>gi|144953895 nidogen 2 precursor [Homo sapiens]
          Length = 1375

 Score = 25.8 bits (55), Expect = 7.8
 Identities = 17/73 (23%), Positives = 28/73 (38%), Gaps = 12/73 (16%)

Query: 18  KAEPLQAEDDPLQAKAYEADAQEQRGANDQDFAVSFA--EDASSSLRALGSTRAFTCHCR 75
           ++ P      PL    YE   ++  G+N + F  + A  E    + R           C 
Sbjct: 447 RSYPASGHTTPLSRGTYEVGLEDNIGSNTEVFTYNAANKETCEHNHR----------QCS 496

Query: 76  RSCYSTEYSYGTC 88
           R  + T+Y+ G C
Sbjct: 497 RHAFCTDYATGFC 509


>gi|148727255 microtubule associated serine/threonine kinase family
           member 4 isoform a [Homo sapiens]
          Length = 2434

 Score = 25.8 bits (55), Expect = 7.8
 Identities = 18/56 (32%), Positives = 28/56 (50%), Gaps = 8/56 (14%)

Query: 15  LQAKAE---PLQAEDDPL-----QAKAYEADAQEQRGANDQDFAVSFAEDASSSLR 62
           L+ KAE    L++EDD         K +  + +E+   ND+DF V   + +S S R
Sbjct: 663 LRQKAEFIPQLESEDDTSYFDTRSEKYHHMETEEEDDTNDEDFNVEIRQFSSCSHR 718


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.322    0.129    0.384 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 3,244,041
Number of Sequences: 37866
Number of extensions: 107055
Number of successful extensions: 404
Number of sequences better than 10.0: 11
Number of HSP's better than 10.0 without gapping: 9
Number of HSP's successfully gapped in prelim test: 2
Number of HSP's that attempted gapping in prelim test: 383
Number of HSP's gapped (non-prelim): 11
length of query: 100
length of database: 18,247,518
effective HSP length: 71
effective length of query: 29
effective length of database: 15,559,032
effective search space: 451211928
effective search space used: 451211928
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (22.0 bits)
S2: 55 (25.8 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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