Guide to the Human Genome
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Search of human proteins with 4502171

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|4502171 adenine phosphoribosyltransferase isoform a [Homo
sapiens]
         (180 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|4502171 adenine phosphoribosyltransferase isoform a [Homo sap...   356   7e-99
gi|71773201 adenine phosphoribosyltransferase isoform b [Homo sa...   266   9e-72
gi|40789249 aspartyl-tRNA synthetase 2, mitochondrial [Homo sapi...    31   0.66 
gi|223555935 dynein, axonemal, heavy polypeptide 14 isoform 1 [H...    29   2.5  
gi|223555933 dynein, axonemal, heavy polypeptide 14 isoform 2 [H...    29   2.5  
gi|239750109 PREDICTED: similar to unc-93 homolog B1 (C. elegans...    29   2.5  
gi|239744415 PREDICTED: similar to unc-93 homolog B1 (C. elegans...    29   2.5  
gi|149944493 dynein, axonemal, heavy polypeptide 14 isoform 3 [H...    29   2.5  
gi|13569870 ubiquitin related modifier 1 homolog isoform a [Homo...    28   3.3  
gi|38045948 ubiquitin-like modifier activating enzyme 7 [Homo sa...    28   3.3  
gi|23397659 alpha/beta hydrolase domain containing protein 2 [Ho...    28   4.3  
gi|23397661 alpha/beta hydrolase domain containing protein 2 [Ho...    28   4.3  
gi|9910262 phosphoribosyl transferase domain containing 1 [Homo ...    28   5.6  
gi|189409124 armadillo repeat containing 3 [Homo sapiens]              27   7.3  
gi|18375650 protein tyrosine phosphatase, non-receptor type 13 i...    27   7.3  
gi|18375648 protein tyrosine phosphatase, non-receptor type 13 i...    27   7.3  
gi|18375646 protein tyrosine phosphatase, non-receptor type 13 i...    27   7.3  
gi|5453992 protein tyrosine phosphatase, non-receptor type 13 is...    27   7.3  
gi|4507835 uridine monophosphate synthase [Homo sapiens]               27   9.5  
gi|33469919 minichromosome maintenance complex component 4 [Homo...    27   9.5  
gi|33469917 minichromosome maintenance complex component 4 [Homo...    27   9.5  
gi|122056683 FRAS1 related extracellular matrix 1 [Homo sapiens]       27   9.5  

>gi|4502171 adenine phosphoribosyltransferase isoform a [Homo
           sapiens]
          Length = 180

 Score =  356 bits (913), Expect = 7e-99
 Identities = 180/180 (100%), Positives = 180/180 (100%)

Query: 1   MADSELQLVEQRIRSFPDFPTPGVVFRDISPVLKDPASFRAAIGLLARHLKATHGGRIDY 60
           MADSELQLVEQRIRSFPDFPTPGVVFRDISPVLKDPASFRAAIGLLARHLKATHGGRIDY
Sbjct: 1   MADSELQLVEQRIRSFPDFPTPGVVFRDISPVLKDPASFRAAIGLLARHLKATHGGRIDY 60

Query: 61  IAGLDSRGFLFGPSLAQELGLGCVLIRKRGKLPGPTLWASYSLEYGKAELEIQKDALEPG 120
           IAGLDSRGFLFGPSLAQELGLGCVLIRKRGKLPGPTLWASYSLEYGKAELEIQKDALEPG
Sbjct: 61  IAGLDSRGFLFGPSLAQELGLGCVLIRKRGKLPGPTLWASYSLEYGKAELEIQKDALEPG 120

Query: 121 QRVVVVDDLLATGGTMNAACELLGRLQAEVLECVSLVELTSLKGREKLAPVPFFSLLQYE 180
           QRVVVVDDLLATGGTMNAACELLGRLQAEVLECVSLVELTSLKGREKLAPVPFFSLLQYE
Sbjct: 121 QRVVVVDDLLATGGTMNAACELLGRLQAEVLECVSLVELTSLKGREKLAPVPFFSLLQYE 180


>gi|71773201 adenine phosphoribosyltransferase isoform b [Homo
           sapiens]
          Length = 134

 Score =  266 bits (679), Expect = 9e-72
 Identities = 133/133 (100%), Positives = 133/133 (100%)

Query: 1   MADSELQLVEQRIRSFPDFPTPGVVFRDISPVLKDPASFRAAIGLLARHLKATHGGRIDY 60
           MADSELQLVEQRIRSFPDFPTPGVVFRDISPVLKDPASFRAAIGLLARHLKATHGGRIDY
Sbjct: 1   MADSELQLVEQRIRSFPDFPTPGVVFRDISPVLKDPASFRAAIGLLARHLKATHGGRIDY 60

Query: 61  IAGLDSRGFLFGPSLAQELGLGCVLIRKRGKLPGPTLWASYSLEYGKAELEIQKDALEPG 120
           IAGLDSRGFLFGPSLAQELGLGCVLIRKRGKLPGPTLWASYSLEYGKAELEIQKDALEPG
Sbjct: 61  IAGLDSRGFLFGPSLAQELGLGCVLIRKRGKLPGPTLWASYSLEYGKAELEIQKDALEPG 120

Query: 121 QRVVVVDDLLATG 133
           QRVVVVDDLLATG
Sbjct: 121 QRVVVVDDLLATG 133


>gi|40789249 aspartyl-tRNA synthetase 2, mitochondrial [Homo
           sapiens]
          Length = 645

 Score = 30.8 bits (68), Expect = 0.66
 Identities = 16/32 (50%), Positives = 20/32 (62%), Gaps = 3/32 (9%)

Query: 127 DDLLATGGTMNAACELLGRLQAEVLECVSLVE 158
           D +L T G  N AC LLG+L+   LEC  L+E
Sbjct: 436 DVVLLTAGEHNKACSLLGKLR---LECADLLE 464


>gi|223555935 dynein, axonemal, heavy polypeptide 14 isoform 1 [Homo
           sapiens]
          Length = 4515

 Score = 28.9 bits (63), Expect = 2.5
 Identities = 14/34 (41%), Positives = 22/34 (64%)

Query: 85  LIRKRGKLPGPTLWASYSLEYGKAELEIQKDALE 118
           +IR R KL   T+   +SL+YG +++ IQK  L+
Sbjct: 133 IIRLREKLGWQTILPQHSLKYGSSKIAIQKITLK 166


>gi|223555933 dynein, axonemal, heavy polypeptide 14 isoform 2 [Homo
           sapiens]
          Length = 453

 Score = 28.9 bits (63), Expect = 2.5
 Identities = 14/34 (41%), Positives = 22/34 (64%)

Query: 85  LIRKRGKLPGPTLWASYSLEYGKAELEIQKDALE 118
           +IR R KL   T+   +SL+YG +++ IQK  L+
Sbjct: 133 IIRLREKLGWQTILPQHSLKYGSSKIAIQKITLK 166


>gi|239750109 PREDICTED: similar to unc-93 homolog B1 (C. elegans)
           [Homo sapiens]
          Length = 529

 Score = 28.9 bits (63), Expect = 2.5
 Identities = 20/58 (34%), Positives = 25/58 (43%), Gaps = 4/58 (6%)

Query: 11  QRIRSFPDFPTPGVVFRDISPVLKDPAS----FRAAIGLLARHLKATHGGRIDYIAGL 64
           QR R  P+   PG     + P    PAS    FRA +GL     +   GG  D + GL
Sbjct: 410 QRARQTPEAHPPGACVGILGPPATIPASDRVYFRATVGLSCDAHEKQAGGGADPLQGL 467


>gi|239744415 PREDICTED: similar to unc-93 homolog B1 (C. elegans)
           [Homo sapiens]
          Length = 503

 Score = 28.9 bits (63), Expect = 2.5
 Identities = 20/58 (34%), Positives = 25/58 (43%), Gaps = 4/58 (6%)

Query: 11  QRIRSFPDFPTPGVVFRDISPVLKDPAS----FRAAIGLLARHLKATHGGRIDYIAGL 64
           QR R  P+   PG     + P    PAS    FRA +GL     +   GG  D + GL
Sbjct: 384 QRARQTPEAHPPGACVGILGPPATIPASDRVYFRATVGLSCDAHEKQAGGGADPLQGL 441


>gi|149944493 dynein, axonemal, heavy polypeptide 14 isoform 3 [Homo
           sapiens]
          Length = 228

 Score = 28.9 bits (63), Expect = 2.5
 Identities = 14/34 (41%), Positives = 22/34 (64%)

Query: 85  LIRKRGKLPGPTLWASYSLEYGKAELEIQKDALE 118
           +IR R KL   T+   +SL+YG +++ IQK  L+
Sbjct: 133 IIRLREKLGWQTILPQHSLKYGSSKIAIQKITLK 166


>gi|13569870 ubiquitin related modifier 1 homolog isoform a [Homo
           sapiens]
          Length = 101

 Score = 28.5 bits (62), Expect = 3.3
 Identities = 20/68 (29%), Positives = 35/68 (51%), Gaps = 10/68 (14%)

Query: 97  LWASYSLEYGKAELEIQKDALEPGQRVVVVDDLLATGGTMNAACELLGRLQAEVLECVSL 156
           +W   +L   + EL IQ D++ PG  V++ D          A  ELLG L  ++ +  S+
Sbjct: 43  IWIKKNLLKERPELFIQGDSVRPGILVLIND----------ADWELLGELDYQLQDQDSV 92

Query: 157 VELTSLKG 164
           + +++L G
Sbjct: 93  LFISTLHG 100


>gi|38045948 ubiquitin-like modifier activating enzyme 7 [Homo
           sapiens]
          Length = 1012

 Score = 28.5 bits (62), Expect = 3.3
 Identities = 33/144 (22%), Positives = 66/144 (45%), Gaps = 18/144 (12%)

Query: 28  DISPVLKDPASFRAAIGLLARHLKATHGGRIDYIAGLDSRGFLFGPSLAQELGLGCVLIR 87
           D S +L +    R    L +  ++   G R+  ++GL   G     +L   +G+G + + 
Sbjct: 5   DASKLLDEELYSRQLYVLGSPAMQRIQGARV-LVSGLQGLGAEVAKNLVL-MGVGSLTLH 62

Query: 88  KRGKLPGPTLWASYSLEYGKAELEIQKDALEPGQRVVVVDDLLATGGTMNAACELL---G 144
                P PT W+  + ++  +E ++++   E  Q      +LLA    +N A +++   G
Sbjct: 63  D----PHPTCWSDLAAQFLLSEQDLERSRAEASQ------ELLA---QLNRAVQVVVHTG 109

Query: 145 RLQAEVLECVSLVELTSLKGREKL 168
            +  ++L    +V LT+ K  E+L
Sbjct: 110 DITEDLLLDFQVVVLTAAKLEEQL 133


>gi|23397659 alpha/beta hydrolase domain containing protein 2 [Homo
           sapiens]
          Length = 425

 Score = 28.1 bits (61), Expect = 4.3
 Identities = 32/100 (32%), Positives = 45/100 (45%), Gaps = 14/100 (14%)

Query: 76  AQELGLGCVLIRKRGKLPGPTLWASYSLEYG-----KAELEIQKDALEPGQRVVVVDDLL 130
           AQ+ G  C ++   G LP   L +     YG      A +   K      Q VVV   L 
Sbjct: 150 AQKNGYRCAVLNHLGALPNIELTSPRMFTYGCTWEFGAMVNYIKKTYPLTQLVVVGFSL- 208

Query: 131 ATGGTMNAACELLGRLQA---EVLECVSLVE-LTSLKGRE 166
             GG  N  C+ LG  QA   +VL CVS+ +  ++L+ +E
Sbjct: 209 --GG--NIVCKYLGETQANQEKVLCCVSVCQGYSALRAQE 244


>gi|23397661 alpha/beta hydrolase domain containing protein 2 [Homo
           sapiens]
          Length = 425

 Score = 28.1 bits (61), Expect = 4.3
 Identities = 32/100 (32%), Positives = 45/100 (45%), Gaps = 14/100 (14%)

Query: 76  AQELGLGCVLIRKRGKLPGPTLWASYSLEYG-----KAELEIQKDALEPGQRVVVVDDLL 130
           AQ+ G  C ++   G LP   L +     YG      A +   K      Q VVV   L 
Sbjct: 150 AQKNGYRCAVLNHLGALPNIELTSPRMFTYGCTWEFGAMVNYIKKTYPLTQLVVVGFSL- 208

Query: 131 ATGGTMNAACELLGRLQA---EVLECVSLVE-LTSLKGRE 166
             GG  N  C+ LG  QA   +VL CVS+ +  ++L+ +E
Sbjct: 209 --GG--NIVCKYLGETQANQEKVLCCVSVCQGYSALRAQE 244


>gi|9910262 phosphoribosyl transferase domain containing 1 [Homo
           sapiens]
          Length = 225

 Score = 27.7 bits (60), Expect = 5.6
 Identities = 11/38 (28%), Positives = 24/38 (63%)

Query: 120 GQRVVVVDDLLATGGTMNAACELLGRLQAEVLECVSLV 157
           G+ V++V+D++ TG TM A    + + +  +++  SL+
Sbjct: 134 GKNVLIVEDVVGTGRTMKALLSNIEKYKPNMIKVASLL 171


>gi|189409124 armadillo repeat containing 3 [Homo sapiens]
          Length = 872

 Score = 27.3 bits (59), Expect = 7.3
 Identities = 23/78 (29%), Positives = 35/78 (44%), Gaps = 24/78 (30%)

Query: 67  RGFLFGPSLAQELGLGCVLIRKRGKLPGPTLWASYSLEYGKA--ELEIQKDALE------ 118
           R  LF  +LA  +G+GC L+R                EYG+A  E+ +Q D+ +      
Sbjct: 798 RALLF-KALADRIGIGCSLVRG---------------EYGRAWNEVMLQNDSRKGVIGGL 841

Query: 119 PGQRVVVVDDLLATGGTM 136
           P   + V+D +   GG M
Sbjct: 842 PAPEMYVIDLMFHPGGLM 859


>gi|18375650 protein tyrosine phosphatase, non-receptor type 13
            isoform 4 [Homo sapiens]
          Length = 2490

 Score = 27.3 bits (59), Expect = 7.3
 Identities = 19/67 (28%), Positives = 35/67 (52%), Gaps = 10/67 (14%)

Query: 106  GKAELEIQKDALEPGQRVVVVDDLLATGGTMNAACELLGRLQAEVLECVSLVELTSLKGR 165
            G A+L+     L+PG R++ V+ +   G + +AA E+L     +V   +S       + +
Sbjct: 1130 GPADLD---GCLKPGDRLISVNSVSLEGVSHHAAIEILQNAPEDVTLVIS-------QPK 1179

Query: 166  EKLAPVP 172
            EK++ VP
Sbjct: 1180 EKISKVP 1186


>gi|18375648 protein tyrosine phosphatase, non-receptor type 13
           isoform 3 [Homo sapiens]
          Length = 2294

 Score = 27.3 bits (59), Expect = 7.3
 Identities = 19/67 (28%), Positives = 35/67 (52%), Gaps = 10/67 (14%)

Query: 106 GKAELEIQKDALEPGQRVVVVDDLLATGGTMNAACELLGRLQAEVLECVSLVELTSLKGR 165
           G A+L+     L+PG R++ V+ +   G + +AA E+L     +V   +S       + +
Sbjct: 939 GPADLD---GCLKPGDRLISVNSVSLEGVSHHAAIEILQNAPEDVTLVIS-------QPK 988

Query: 166 EKLAPVP 172
           EK++ VP
Sbjct: 989 EKISKVP 995


>gi|18375646 protein tyrosine phosphatase, non-receptor type 13
            isoform 1 [Homo sapiens]
          Length = 2485

 Score = 27.3 bits (59), Expect = 7.3
 Identities = 19/67 (28%), Positives = 35/67 (52%), Gaps = 10/67 (14%)

Query: 106  GKAELEIQKDALEPGQRVVVVDDLLATGGTMNAACELLGRLQAEVLECVSLVELTSLKGR 165
            G A+L+     L+PG R++ V+ +   G + +AA E+L     +V   +S       + +
Sbjct: 1130 GPADLD---GCLKPGDRLISVNSVSLEGVSHHAAIEILQNAPEDVTLVIS-------QPK 1179

Query: 166  EKLAPVP 172
            EK++ VP
Sbjct: 1180 EKISKVP 1186


>gi|5453992 protein tyrosine phosphatase, non-receptor type 13 isoform
            2 [Homo sapiens]
          Length = 2466

 Score = 27.3 bits (59), Expect = 7.3
 Identities = 19/67 (28%), Positives = 35/67 (52%), Gaps = 10/67 (14%)

Query: 106  GKAELEIQKDALEPGQRVVVVDDLLATGGTMNAACELLGRLQAEVLECVSLVELTSLKGR 165
            G A+L+     L+PG R++ V+ +   G + +AA E+L     +V   +S       + +
Sbjct: 1111 GPADLD---GCLKPGDRLISVNSVSLEGVSHHAAIEILQNAPEDVTLVIS-------QPK 1160

Query: 166  EKLAPVP 172
            EK++ VP
Sbjct: 1161 EKISKVP 1167


>gi|4507835 uridine monophosphate synthase [Homo sapiens]
          Length = 480

 Score = 26.9 bits (58), Expect = 9.5
 Identities = 14/65 (21%), Positives = 36/65 (55%), Gaps = 3/65 (4%)

Query: 104 EYGKAELEIQKDALEPGQRVVVVDDLLATGGTMNAACELLGRLQAEVLECVSLVELTSLK 163
           +YG   L   +  + PG+  ++++D++ +G ++    E+L +   +V + + L++     
Sbjct: 102 DYGTKRLV--EGTINPGETCLIIEDVVTSGSSVLETVEVLQKEGLKVTDAIVLLD-REQG 158

Query: 164 GREKL 168
           G++KL
Sbjct: 159 GKDKL 163


>gi|33469919 minichromosome maintenance complex component 4 [Homo
           sapiens]
          Length = 863

 Score = 26.9 bits (58), Expect = 9.5
 Identities = 15/50 (30%), Positives = 22/50 (44%)

Query: 85  LIRKRGKLPGPTLWASYSLEYGKAELEIQKDALEPGQRVVVVDDLLATGG 134
           LI  +GK P       +    G++++ I KD  E   R +  DD L   G
Sbjct: 808 LILSKGKTPALKYQQLFEDIRGQSDIAITKDMFEEALRALADDDFLTVTG 857


>gi|33469917 minichromosome maintenance complex component 4 [Homo
           sapiens]
          Length = 863

 Score = 26.9 bits (58), Expect = 9.5
 Identities = 15/50 (30%), Positives = 22/50 (44%)

Query: 85  LIRKRGKLPGPTLWASYSLEYGKAELEIQKDALEPGQRVVVVDDLLATGG 134
           LI  +GK P       +    G++++ I KD  E   R +  DD L   G
Sbjct: 808 LILSKGKTPALKYQQLFEDIRGQSDIAITKDMFEEALRALADDDFLTVTG 857


>gi|122056683 FRAS1 related extracellular matrix 1 [Homo sapiens]
          Length = 2179

 Score = 26.9 bits (58), Expect = 9.5
 Identities = 10/20 (50%), Positives = 15/20 (75%)

Query: 72   GPSLAQELGLGCVLIRKRGK 91
            GPS   +LG  CVL++++GK
Sbjct: 2140 GPSQRSKLGKSCVLVQRQGK 2159


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.321    0.141    0.411 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 7,262,717
Number of Sequences: 37866
Number of extensions: 312256
Number of successful extensions: 597
Number of sequences better than 10.0: 22
Number of HSP's better than 10.0 without gapping: 8
Number of HSP's successfully gapped in prelim test: 14
Number of HSP's that attempted gapping in prelim test: 583
Number of HSP's gapped (non-prelim): 26
length of query: 180
length of database: 18,247,518
effective HSP length: 96
effective length of query: 84
effective length of database: 14,612,382
effective search space: 1227440088
effective search space used: 1227440088
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 58 (26.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
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