Search of human proteins with 44680145

Search of human proteins with 44680145

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|44680145 solute carrier family 23 (nucleobase transporters),
member 1 isoform a [Homo sapiens]
         (598 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|44680145 solute carrier family 23 (nucleobase transporters), ...  1206   0.0  
gi|44680143 solute carrier family 23 (nucleobase transporters), ...  1200   0.0  
gi|44680148 solute carrier family 23 (nucleobase transporters), ...   786   0.0  
gi|40316845 solute carrier family 23 (nucleobase transporters), ...   786   0.0  
gi|222080105 solute carrier family 23 (nucleobase transporters),...   285   6e-77
gi|222080107 solute carrier family 23 (nucleobase transporters),...   278   8e-75
gi|158635944 solute carrier family 23 (nucleobase transporters),...   104   2e-22
gi|196123590 NADH dehydrogenase subunit 6 [Homo sapiens neandert...    35   0.15 
gi|251831118 NADH dehydrogenase subunit 6 [Homo sapiens]               35   0.15 
gi|171543823 gamma-glutamyltransferase 6 isoform b [Homo sapiens]      30   6.3  
gi|136255216 proline-rich transmembrane protein 3 [Homo sapiens]       30   8.3  

>gi|44680145 solute carrier family 23 (nucleobase transporters),
           member 1 isoform a [Homo sapiens]
          Length = 598

 Score = 1206 bits (3120), Expect = 0.0
 Identities = 598/598 (100%), Positives = 598/598 (100%)

Query: 1   MRAQEDLEGRTQHETTRDPSTPLPTEPKFDMLYKIEDVPPWYLCILLGFQHYLTCFSGTI 60
           MRAQEDLEGRTQHETTRDPSTPLPTEPKFDMLYKIEDVPPWYLCILLGFQHYLTCFSGTI
Sbjct: 1   MRAQEDLEGRTQHETTRDPSTPLPTEPKFDMLYKIEDVPPWYLCILLGFQHYLTCFSGTI 60

Query: 61  AVPFLLAEALCVGHDQHMVSQLIGTIFTCVGITTLIQTTVGIRLPLFQASAFAFLVPAKA 120
           AVPFLLAEALCVGHDQHMVSQLIGTIFTCVGITTLIQTTVGIRLPLFQASAFAFLVPAKA
Sbjct: 61  AVPFLLAEALCVGHDQHMVSQLIGTIFTCVGITTLIQTTVGIRLPLFQASAFAFLVPAKA 120

Query: 121 ILALERWKCPPEEEIYGNWSLPLNTSHIWHPRIREVQGAIMVSSVVEVVIGLLGLPGALL 180
           ILALERWKCPPEEEIYGNWSLPLNTSHIWHPRIREVQGAIMVSSVVEVVIGLLGLPGALL
Sbjct: 121 ILALERWKCPPEEEIYGNWSLPLNTSHIWHPRIREVQGAIMVSSVVEVVIGLLGLPGALL 180

Query: 181 NYIGPLTVTPTVSLIGLSVFQAAGDRAGSHWGISACSILLIILFSQYLRNLTFLLPVYRW 240
           NYIGPLTVTPTVSLIGLSVFQAAGDRAGSHWGISACSILLIILFSQYLRNLTFLLPVYRW
Sbjct: 181 NYIGPLTVTPTVSLIGLSVFQAAGDRAGSHWGISACSILLIILFSQYLRNLTFLLPVYRW 240

Query: 241 GKGLTLLRIQIFKMFPIMLAIMTVWLLCYVLTLTDVLPTDPKAYGFQARTDARGDIMAIA 300
           GKGLTLLRIQIFKMFPIMLAIMTVWLLCYVLTLTDVLPTDPKAYGFQARTDARGDIMAIA
Sbjct: 241 GKGLTLLRIQIFKMFPIMLAIMTVWLLCYVLTLTDVLPTDPKAYGFQARTDARGDIMAIA 300

Query: 301 PWIRIPYPCQWGLPTVTAAAVLGMFSATLAGIIESIGDYYACARLAGAPPPPVHAINRGI 360
           PWIRIPYPCQWGLPTVTAAAVLGMFSATLAGIIESIGDYYACARLAGAPPPPVHAINRGI
Sbjct: 301 PWIRIPYPCQWGLPTVTAAAVLGMFSATLAGIIESIGDYYACARLAGAPPPPVHAINRGI 360

Query: 361 FTEGICCIIAGLLGTGNGSTSSSPNIGVLGITKVGSRRVVQYGAAIMLVLGTIGKFTALF 420
           FTEGICCIIAGLLGTGNGSTSSSPNIGVLGITKVGSRRVVQYGAAIMLVLGTIGKFTALF
Sbjct: 361 FTEGICCIIAGLLGTGNGSTSSSPNIGVLGITKVGSRRVVQYGAAIMLVLGTIGKFTALF 420

Query: 421 ASLPDPILGGMFCTLFGMITAVGLSNLQFVDMNSSRNLFVLGFSMFFGLTLPNYLESNPG 480
           ASLPDPILGGMFCTLFGMITAVGLSNLQFVDMNSSRNLFVLGFSMFFGLTLPNYLESNPG
Sbjct: 421 ASLPDPILGGMFCTLFGMITAVGLSNLQFVDMNSSRNLFVLGFSMFFGLTLPNYLESNPG 480

Query: 481 AINTGILEVDQILIVLLTTEMFVGGCLAFILDNTVPGSPEERGLIQWKAGAHANSDMSSS 540
           AINTGILEVDQILIVLLTTEMFVGGCLAFILDNTVPGSPEERGLIQWKAGAHANSDMSSS
Sbjct: 481 AINTGILEVDQILIVLLTTEMFVGGCLAFILDNTVPGSPEERGLIQWKAGAHANSDMSSS 540

Query: 541 LKSYDFPIGMGIVKRITFLKYIPICPVFKGFSSSSKDQIAIPEDTPENTETASVCTKV 598
           LKSYDFPIGMGIVKRITFLKYIPICPVFKGFSSSSKDQIAIPEDTPENTETASVCTKV
Sbjct: 541 LKSYDFPIGMGIVKRITFLKYIPICPVFKGFSSSSKDQIAIPEDTPENTETASVCTKV 598


>gi|44680143 solute carrier family 23 (nucleobase transporters),
           member 1 isoform b [Homo sapiens]
          Length = 602

 Score = 1200 bits (3105), Expect = 0.0
 Identities = 598/602 (99%), Positives = 598/602 (99%), Gaps = 4/602 (0%)

Query: 1   MRAQEDLEGRTQHETTRDPSTPLPTEPKFDMLYKIEDVPPWYLCILLGFQHYLTCFSGTI 60
           MRAQEDLEGRTQHETTRDPSTPLPTEPKFDMLYKIEDVPPWYLCILLGFQHYLTCFSGTI
Sbjct: 1   MRAQEDLEGRTQHETTRDPSTPLPTEPKFDMLYKIEDVPPWYLCILLGFQHYLTCFSGTI 60

Query: 61  AVPFLLAEALCVGHDQHMVSQLIGTIFTCVGITTLIQTTVGIRLPLFQASAFAFLVPAKA 120
           AVPFLLAEALCVGHDQHMVSQLIGTIFTCVGITTLIQTTVGIRLPLFQASAFAFLVPAKA
Sbjct: 61  AVPFLLAEALCVGHDQHMVSQLIGTIFTCVGITTLIQTTVGIRLPLFQASAFAFLVPAKA 120

Query: 121 ILALERWKCPPEEEIYGNWSLPLNTSHIWHPRIREV----QGAIMVSSVVEVVIGLLGLP 176
           ILALERWKCPPEEEIYGNWSLPLNTSHIWHPRIREV    QGAIMVSSVVEVVIGLLGLP
Sbjct: 121 ILALERWKCPPEEEIYGNWSLPLNTSHIWHPRIREVGLHVQGAIMVSSVVEVVIGLLGLP 180

Query: 177 GALLNYIGPLTVTPTVSLIGLSVFQAAGDRAGSHWGISACSILLIILFSQYLRNLTFLLP 236
           GALLNYIGPLTVTPTVSLIGLSVFQAAGDRAGSHWGISACSILLIILFSQYLRNLTFLLP
Sbjct: 181 GALLNYIGPLTVTPTVSLIGLSVFQAAGDRAGSHWGISACSILLIILFSQYLRNLTFLLP 240

Query: 237 VYRWGKGLTLLRIQIFKMFPIMLAIMTVWLLCYVLTLTDVLPTDPKAYGFQARTDARGDI 296
           VYRWGKGLTLLRIQIFKMFPIMLAIMTVWLLCYVLTLTDVLPTDPKAYGFQARTDARGDI
Sbjct: 241 VYRWGKGLTLLRIQIFKMFPIMLAIMTVWLLCYVLTLTDVLPTDPKAYGFQARTDARGDI 300

Query: 297 MAIAPWIRIPYPCQWGLPTVTAAAVLGMFSATLAGIIESIGDYYACARLAGAPPPPVHAI 356
           MAIAPWIRIPYPCQWGLPTVTAAAVLGMFSATLAGIIESIGDYYACARLAGAPPPPVHAI
Sbjct: 301 MAIAPWIRIPYPCQWGLPTVTAAAVLGMFSATLAGIIESIGDYYACARLAGAPPPPVHAI 360

Query: 357 NRGIFTEGICCIIAGLLGTGNGSTSSSPNIGVLGITKVGSRRVVQYGAAIMLVLGTIGKF 416
           NRGIFTEGICCIIAGLLGTGNGSTSSSPNIGVLGITKVGSRRVVQYGAAIMLVLGTIGKF
Sbjct: 361 NRGIFTEGICCIIAGLLGTGNGSTSSSPNIGVLGITKVGSRRVVQYGAAIMLVLGTIGKF 420

Query: 417 TALFASLPDPILGGMFCTLFGMITAVGLSNLQFVDMNSSRNLFVLGFSMFFGLTLPNYLE 476
           TALFASLPDPILGGMFCTLFGMITAVGLSNLQFVDMNSSRNLFVLGFSMFFGLTLPNYLE
Sbjct: 421 TALFASLPDPILGGMFCTLFGMITAVGLSNLQFVDMNSSRNLFVLGFSMFFGLTLPNYLE 480

Query: 477 SNPGAINTGILEVDQILIVLLTTEMFVGGCLAFILDNTVPGSPEERGLIQWKAGAHANSD 536
           SNPGAINTGILEVDQILIVLLTTEMFVGGCLAFILDNTVPGSPEERGLIQWKAGAHANSD
Sbjct: 481 SNPGAINTGILEVDQILIVLLTTEMFVGGCLAFILDNTVPGSPEERGLIQWKAGAHANSD 540

Query: 537 MSSSLKSYDFPIGMGIVKRITFLKYIPICPVFKGFSSSSKDQIAIPEDTPENTETASVCT 596
           MSSSLKSYDFPIGMGIVKRITFLKYIPICPVFKGFSSSSKDQIAIPEDTPENTETASVCT
Sbjct: 541 MSSSLKSYDFPIGMGIVKRITFLKYIPICPVFKGFSSSSKDQIAIPEDTPENTETASVCT 600

Query: 597 KV 598
           KV
Sbjct: 601 KV 602


>gi|44680148 solute carrier family 23 (nucleobase transporters),
           member 2 [Homo sapiens]
          Length = 650

 Score =  786 bits (2029), Expect = 0.0
 Identities = 373/544 (68%), Positives = 449/544 (82%), Gaps = 3/544 (0%)

Query: 30  DMLYKIEDVPPWYLCILLGFQHYLTCFSGTIAVPFLLAEALCVGHDQHMVSQLIGTIFTC 89
           DM+Y IEDVPPWYLCI LG QHYLTCFSGTIAVPFLLA+A+CVG+DQ   SQLIGTIF C
Sbjct: 88  DMIYTIEDVPPWYLCIFLGLQHYLTCFSGTIAVPFLLADAMCVGYDQWATSQLIGTIFFC 147

Query: 90  VGITTLIQTTVGIRLPLFQASAFAFLVPAKAILALERWKCPPEEEIYGNWSLPL-NTSHI 148
           VGITTL+QTT G RLPLFQASAFAFL PA+AIL+L++WKC   +    N +  L +T HI
Sbjct: 148 VGITTLLQTTFGCRLPLFQASAFAFLAPARAILSLDKWKCNTTDVSVANGTAELLHTEHI 207

Query: 149 WHPRIREVQGAIMVSSVVEVVIGLLGLPGALLNYIGPLTVTPTVSLIGLSVFQAAGDRAG 208
           W+PRIRE+QGAI++SS++EVVIGLLGLPGALL YIGPLT+TPTV+LIGLS FQAAG+RAG
Sbjct: 208 WYPRIREIQGAIIMSSLIEVVIGLLGLPGALLKYIGPLTITPTVALIGLSGFQAAGERAG 267

Query: 209 SHWGISACSILLIILFSQYLRNLTFLLPVYRWGKGLTLLRIQIFKMFPIMLAIMTVWLLC 268
            HWGI+  +I L++LFSQY RN+ F LP+Y+  KG T  ++Q+FKMFPI+LAI+  WLLC
Sbjct: 268 KHWGIAMLTIFLVLLFSQYARNVKFPLPIYKSKKGWTAYKLQLFKMFPIILAILVSWLLC 327

Query: 269 YVLTLTDVLPTDPKAYGFQARTDARGDIMAIAPWIRIPYPCQWGLPTVTAAAVLGMFSAT 328
           ++ T+TDV P D   YGF ARTDAR  ++ +APW ++PYP QWGLPTV+AA V+GM SA 
Sbjct: 328 FIFTVTDVFPPDSTKYGFYARTDARQGVLLVAPWFKVPYPFQWGLPTVSAAGVIGMLSAV 387

Query: 329 LAGIIESIGDYYACARLAGAPPPPVHAINRGIFTEGICCIIAGLLGTGNGSTSSSPNIGV 388
           +A IIESIGDYYACARL+ APPPP+HAINRGIF EG+ C++ G+ GTGNGSTSSSPNIGV
Sbjct: 388 VASIIESIGDYYACARLSCAPPPPIHAINRGIFVEGLSCVLDGIFGTGNGSTSSSPNIGV 447

Query: 389 LGITKVGSRRVVQYGAAIMLVLGTIGKFTALFASLPDPILGGMFCTLFGMITAVGLSNLQ 448
           LGITKVGSRRV+Q GAA+ML LG IGKF+ALFASLPDP+LG +FCTLFGMITAVGLSNLQ
Sbjct: 448 LGITKVGSRRVIQCGAALMLALGMIGKFSALFASLPDPVLGALFCTLFGMITAVGLSNLQ 507

Query: 449 FVDMNSSRNLFVLGFSMFFGLTLPNYLESNPGAINTGILEVDQILIVLLTTEMFVGGCLA 508
           F+D+NSSRNLFVLGFS+FFGL LP+YL  NP  + TGI  +DQ+L VLLTT MFVGGC+A
Sbjct: 508 FIDLNSSRNLFVLGFSIFFGLVLPSYLRQNP--LVTGITGIDQVLNVLLTTAMFVGGCVA 565

Query: 509 FILDNTVPGSPEERGLIQWKAGAHANSDMSSSLKSYDFPIGMGIVKRITFLKYIPICPVF 568
           FILDNT+PG+PEERG+ +WK G    +     ++SY+ P GM I+K+     Y+PI P F
Sbjct: 566 FILDNTIPGTPEERGIRKWKKGVGKGNKSLDGMESYNLPFGMNIIKKYRCFSYLPISPTF 625

Query: 569 KGFS 572
            G++
Sbjct: 626 VGYT 629


>gi|40316845 solute carrier family 23 (nucleobase transporters),
           member 2 [Homo sapiens]
          Length = 650

 Score =  786 bits (2029), Expect = 0.0
 Identities = 373/544 (68%), Positives = 449/544 (82%), Gaps = 3/544 (0%)

Query: 30  DMLYKIEDVPPWYLCILLGFQHYLTCFSGTIAVPFLLAEALCVGHDQHMVSQLIGTIFTC 89
           DM+Y IEDVPPWYLCI LG QHYLTCFSGTIAVPFLLA+A+CVG+DQ   SQLIGTIF C
Sbjct: 88  DMIYTIEDVPPWYLCIFLGLQHYLTCFSGTIAVPFLLADAMCVGYDQWATSQLIGTIFFC 147

Query: 90  VGITTLIQTTVGIRLPLFQASAFAFLVPAKAILALERWKCPPEEEIYGNWSLPL-NTSHI 148
           VGITTL+QTT G RLPLFQASAFAFL PA+AIL+L++WKC   +    N +  L +T HI
Sbjct: 148 VGITTLLQTTFGCRLPLFQASAFAFLAPARAILSLDKWKCNTTDVSVANGTAELLHTEHI 207

Query: 149 WHPRIREVQGAIMVSSVVEVVIGLLGLPGALLNYIGPLTVTPTVSLIGLSVFQAAGDRAG 208
           W+PRIRE+QGAI++SS++EVVIGLLGLPGALL YIGPLT+TPTV+LIGLS FQAAG+RAG
Sbjct: 208 WYPRIREIQGAIIMSSLIEVVIGLLGLPGALLKYIGPLTITPTVALIGLSGFQAAGERAG 267

Query: 209 SHWGISACSILLIILFSQYLRNLTFLLPVYRWGKGLTLLRIQIFKMFPIMLAIMTVWLLC 268
            HWGI+  +I L++LFSQY RN+ F LP+Y+  KG T  ++Q+FKMFPI+LAI+  WLLC
Sbjct: 268 KHWGIAMLTIFLVLLFSQYARNVKFPLPIYKSKKGWTAYKLQLFKMFPIILAILVSWLLC 327

Query: 269 YVLTLTDVLPTDPKAYGFQARTDARGDIMAIAPWIRIPYPCQWGLPTVTAAAVLGMFSAT 328
           ++ T+TDV P D   YGF ARTDAR  ++ +APW ++PYP QWGLPTV+AA V+GM SA 
Sbjct: 328 FIFTVTDVFPPDSTKYGFYARTDARQGVLLVAPWFKVPYPFQWGLPTVSAAGVIGMLSAV 387

Query: 329 LAGIIESIGDYYACARLAGAPPPPVHAINRGIFTEGICCIIAGLLGTGNGSTSSSPNIGV 388
           +A IIESIGDYYACARL+ APPPP+HAINRGIF EG+ C++ G+ GTGNGSTSSSPNIGV
Sbjct: 388 VASIIESIGDYYACARLSCAPPPPIHAINRGIFVEGLSCVLDGIFGTGNGSTSSSPNIGV 447

Query: 389 LGITKVGSRRVVQYGAAIMLVLGTIGKFTALFASLPDPILGGMFCTLFGMITAVGLSNLQ 448
           LGITKVGSRRV+Q GAA+ML LG IGKF+ALFASLPDP+LG +FCTLFGMITAVGLSNLQ
Sbjct: 448 LGITKVGSRRVIQCGAALMLALGMIGKFSALFASLPDPVLGALFCTLFGMITAVGLSNLQ 507

Query: 449 FVDMNSSRNLFVLGFSMFFGLTLPNYLESNPGAINTGILEVDQILIVLLTTEMFVGGCLA 508
           F+D+NSSRNLFVLGFS+FFGL LP+YL  NP  + TGI  +DQ+L VLLTT MFVGGC+A
Sbjct: 508 FIDLNSSRNLFVLGFSIFFGLVLPSYLRQNP--LVTGITGIDQVLNVLLTTAMFVGGCVA 565

Query: 509 FILDNTVPGSPEERGLIQWKAGAHANSDMSSSLKSYDFPIGMGIVKRITFLKYIPICPVF 568
           FILDNT+PG+PEERG+ +WK G    +     ++SY+ P GM I+K+     Y+PI P F
Sbjct: 566 FILDNTIPGTPEERGIRKWKKGVGKGNKSLDGMESYNLPFGMNIIKKYRCFSYLPISPTF 625

Query: 569 KGFS 572
            G++
Sbjct: 626 VGYT 629


>gi|222080105 solute carrier family 23 (nucleobase transporters),
           member 3 isoform 2 [Homo sapiens]
          Length = 610

 Score =  285 bits (730), Expect = 6e-77
 Identities = 169/514 (32%), Positives = 270/514 (52%), Gaps = 26/514 (5%)

Query: 22  PLPTEPKFDMLYKIEDVPPWYLCILLGFQHYLTCFSGTIAVPFLLAEALCVGHDQHMVSQ 81
           P P  P       +    PW L  LL  QH L   S       LL  +L  G   +  SQ
Sbjct: 26  PAPQNPSTHSWDPLCGSLPWGLSCLLALQHVLVMASLLCVSHLLLLCSLSPGGLSYSPSQ 85

Query: 82  LIGTIFTCVGITTLIQTTVGIRLPLFQASAFAFLVPAKAILALERWKCPPEEEIYGNWSL 141
           L+ + F   G++T++QT +G RLPL QA +  FL+PA   L L   K P   +  GN SL
Sbjct: 86  LLASSFFSCGMSTILQTWMGSRLPLVQAPSLEFLIPA---LVLTSQKLPRAIQTPGNSSL 142

Query: 142 PLNTSH--------IWHPRIREVQGAIMVSSVVEVVIGLLGLPGALLNYIGPLTVTPTVS 193
            L+            W+  ++EV GA++VS +++ ++GLLG PG +  + GPL + P++ 
Sbjct: 143 MLHLCRGPSCHGLGHWNTSLQEVSGAVVVSGLLQGMMGLLGSPGHVFPHCGPLVLAPSLV 202

Query: 194 LIGLSVFQAAGDRAGSHWGISACSILLIILFSQYLRNLTF-LLPVYRWGKGLTLLRIQIF 252
           + GLS  +       +HWG++   ILL+++ SQ+L +  F + P  R     T   + +F
Sbjct: 203 VAGLSAHREVAQFCFTHWGLALLVILLMVVCSQHLGSCQFHVCPWRRASTSSTHTPLPVF 262

Query: 253 KMFPIMLAIMTVWLLCYVLTLTDVLPTDPKAYGFQARTDARGDIMAIAPWIRIPYPCQWG 312
           ++  +++ +  VW++   +  + V+P +  A                APWI +P+P +W 
Sbjct: 263 RLLSVLIPVACVWIVSAFVGFS-VIPQELSA-------------PTKAPWIWLPHPGEWN 308

Query: 313 LPTVTAAAVLGMFSATLAGIIESIGDYYACARLAGAPPPPVHAINRGIFTEGICCIIAGL 372
            P +T  A+    S  LA    S+G Y  C RL   PPPP HA +RG+  EG+  ++AGL
Sbjct: 309 WPLLTPRALAAGISMALAASTSSLGCYALCGRLLHLPPPPPHACSRGLSLEGLGSVLAGL 368

Query: 373 LGTGNGSTSSSPNIGVLGITKVGSRRVVQYGAAIMLVLGTIGKFTALFASLPDPILGGMF 432
           LG+  G+ SS PN+G +G+ + GS++V      + + LG   +   L  ++P P++GG+ 
Sbjct: 369 LGSPMGTASSFPNVGKVGLIQAGSQQVAHLVGLLCVGLGLSPRLAQLLTTIPLPVVGGVL 428

Query: 433 CTLFGMITAVGLSNLQFVDMNSSRNLFVLGFSMFFGLTLPNYLESNPGAINTGILEVDQI 492
                ++ + G S+    D++S RN+F++GFS+F  L LP +    P   +TG   +D +
Sbjct: 429 GVTQAVVLSAGFSSFYLADIDSGRNIFIVGFSIFMALLLPRWFREAPVLFSTGWSPLDVL 488

Query: 493 LIVLLTTEMFVGGCLAFILDNTVPGSPEERGLIQ 526
           L  LLT  +F+ G   F+L+NT+PG+  ERGL Q
Sbjct: 489 LHSLLTQPIFLAGLSGFLLENTIPGTQLERGLGQ 522


>gi|222080107 solute carrier family 23 (nucleobase transporters),
           member 3 isoform 3 [Homo sapiens]
          Length = 618

 Score =  278 bits (712), Expect = 8e-75
 Identities = 169/522 (32%), Positives = 270/522 (51%), Gaps = 34/522 (6%)

Query: 22  PLPTEPKFDMLYKIEDVPPWYLCILLGFQHYLTCFSGTIAVPFLLAEALCVGHDQHMVSQ 81
           P P  P       +    PW L  LL  QH L   S       LL  +L  G   +  SQ
Sbjct: 26  PAPQNPSTHSWDPLCGSLPWGLSCLLALQHVLVMASLLCVSHLLLLCSLSPGGLSYSPSQ 85

Query: 82  LIGTIFTCVGITTLIQTTVGIRLPLFQASAFAFLVPAKAILALERWKCPPEEEIYGNW-- 139
           L+ + F   G++T++QT +G RLPL QA +  FL+PA   L L   K P   +  GN   
Sbjct: 86  LLASSFFSCGMSTILQTWMGSRLPLVQAPSLEFLIPA---LVLTSQKLPRAIQTPGNCEH 142

Query: 140 ------SLPLNTSH--------IWHPRIREVQGAIMVSSVVEVVIGLLGLPGALLNYIGP 185
                 SL L+            W+  ++EV GA++VS +++ ++GLLG PG +  + GP
Sbjct: 143 RARARASLMLHLCRGPSCHGLGHWNTSLQEVSGAVVVSGLLQGMMGLLGSPGHVFPHCGP 202

Query: 186 LTVTPTVSLIGLSVFQAAGDRAGSHWGISACSILLIILFSQYLRNLTF-LLPVYRWGKGL 244
           L + P++ + GLS  +       +HWG++   ILL+++ SQ+L +  F + P  R     
Sbjct: 203 LVLAPSLVVAGLSAHREVAQFCFTHWGLALLVILLMVVCSQHLGSCQFHVCPWRRASTSS 262

Query: 245 TLLRIQIFKMFPIMLAIMTVWLLCYVLTLTDVLPTDPKAYGFQARTDARGDIMAIAPWIR 304
           T   + +F++  +++ +  VW++   +  + V+P +  A                APWI 
Sbjct: 263 THTPLPVFRLLSVLIPVACVWIVSAFVGFS-VIPQELSA-------------PTKAPWIW 308

Query: 305 IPYPCQWGLPTVTAAAVLGMFSATLAGIIESIGDYYACARLAGAPPPPVHAINRGIFTEG 364
           +P+P +W  P +T  A+    S  LA    S+G Y  C RL   PPPP HA +RG+  EG
Sbjct: 309 LPHPGEWNWPLLTPRALAAGISMALAASTSSLGCYALCGRLLHLPPPPPHACSRGLSLEG 368

Query: 365 ICCIIAGLLGTGNGSTSSSPNIGVLGITKVGSRRVVQYGAAIMLVLGTIGKFTALFASLP 424
           +  ++AGLLG+  G+ SS PN+G +G+ + GS++V      + + LG   +   L  ++P
Sbjct: 369 LGSVLAGLLGSPMGTASSFPNVGKVGLIQAGSQQVAHLVGLLCVGLGLSPRLAQLLTTIP 428

Query: 425 DPILGGMFCTLFGMITAVGLSNLQFVDMNSSRNLFVLGFSMFFGLTLPNYLESNPGAINT 484
            P++GG+      ++ + G S+    D++S RN+F++GFS+F  L LP +    P   +T
Sbjct: 429 LPVVGGVLGVTQAVVLSAGFSSFYLADIDSGRNIFIVGFSIFMALLLPRWFREAPVLFST 488

Query: 485 GILEVDQILIVLLTTEMFVGGCLAFILDNTVPGSPEERGLIQ 526
           G   +D +L  LLT  +F+ G   F+L+NT+PG+  ERGL Q
Sbjct: 489 GWSPLDVLLHSLLTQPIFLAGLSGFLLENTIPGTQLERGLGQ 530


>gi|158635944 solute carrier family 23 (nucleobase transporters),
           member 3 isoform 1 [Homo sapiens]
          Length = 493

 Score =  104 bits (260), Expect = 2e-22
 Identities = 67/201 (33%), Positives = 101/201 (50%), Gaps = 11/201 (5%)

Query: 22  PLPTEPKFDMLYKIEDVPPWYLCILLGFQHYLTCFSGTIAVPFLLAEALCVGHDQHMVSQ 81
           P P  P       +    PW L  LL  QH L   S       LL  +L  G   +  SQ
Sbjct: 26  PAPQNPSTHSWDPLCGSLPWGLSCLLALQHVLVMASLLCVSHLLLLCSLSPGGLSYSPSQ 85

Query: 82  LIGTIFTCVGITTLIQTTVGIRLPLFQASAFAFLVPAKAILALERWKCPPEEEIYGNWSL 141
           L+ + F   G++T++QT +G RLPL QA +  FL+PA   L L   K P   +  GN SL
Sbjct: 86  LLASSFFSCGMSTILQTWMGSRLPLVQAPSLEFLIPA---LVLTSQKLPRAIQTPGNSSL 142

Query: 142 PLNTSH--------IWHPRIREVQGAIMVSSVVEVVIGLLGLPGALLNYIGPLTVTPTVS 193
            L+            W+  ++EV GA++VS +++ ++GLLG PG +  + GPL + P++ 
Sbjct: 143 MLHLCRGPSCHGLGHWNTSLQEVSGAVVVSGLLQGMMGLLGSPGHVFPHCGPLVLAPSLV 202

Query: 194 LIGLSVFQAAGDRAGSHWGIS 214
           + GLS  +       +HWG++
Sbjct: 203 VAGLSAHREVAQFCFTHWGLA 223



 Score = 94.4 bits (233), Expect = 3e-19
 Identities = 46/136 (33%), Positives = 78/136 (57%)

Query: 391 ITKVGSRRVVQYGAAIMLVLGTIGKFTALFASLPDPILGGMFCTLFGMITAVGLSNLQFV 450
           +T+ GS++V      + + LG   +   L  ++P P++GG+      ++ + G S+    
Sbjct: 270 LTQAGSQQVAHLVGLLCVGLGLSPRLAQLLTTIPLPVVGGVLGVTQAVVLSAGFSSFYLA 329

Query: 451 DMNSSRNLFVLGFSMFFGLTLPNYLESNPGAINTGILEVDQILIVLLTTEMFVGGCLAFI 510
           D++S RN+F++GFS+F  L LP +    P   +TG   +D +L  LLT  +F+ G   F+
Sbjct: 330 DIDSGRNIFIVGFSIFMALLLPRWFREAPVLFSTGWSPLDVLLHSLLTQPIFLAGLSGFL 389

Query: 511 LDNTVPGSPEERGLIQ 526
           L+NT+PG+  ERGL Q
Sbjct: 390 LENTIPGTQLERGLGQ 405


>gi|196123590 NADH dehydrogenase subunit 6 [Homo sapiens
           neanderthalensis]
          Length = 174

 Score = 35.4 bits (80), Expect = 0.15
 Identities = 32/101 (31%), Positives = 48/101 (47%), Gaps = 9/101 (8%)

Query: 405 AIMLVLGTIGKFTALFASLPDPILGGMFCTLFGMITAVGLSNLQFVDMNSSRNLFVLGFS 464
           ++ LV+G +G     F+S P PI GG+   + G++  V + N     M     L  LG  
Sbjct: 9   SVGLVMGFVG-----FSSKPSPIYGGLVLIVSGVVGCVIILNFGGGYMGLMVFLIYLGGM 63

Query: 465 M-FFGLTLPNYLESNPGAINTGILEVDQILIVLLTTEMFVG 504
           M  FG T    +E  P A  +G   V+ ++ VL+   M VG
Sbjct: 64  MVVFGYTTAMAIEEYPEAWGSG---VEVLVSVLVGLAMEVG 101


>gi|251831118 NADH dehydrogenase subunit 6 [Homo sapiens]
          Length = 174

 Score = 35.4 bits (80), Expect = 0.15
 Identities = 32/101 (31%), Positives = 48/101 (47%), Gaps = 9/101 (8%)

Query: 405 AIMLVLGTIGKFTALFASLPDPILGGMFCTLFGMITAVGLSNLQFVDMNSSRNLFVLGFS 464
           ++ LV+G +G     F+S P PI GG+   + G++  V + N     M     L  LG  
Sbjct: 9   SVGLVMGFVG-----FSSKPSPIYGGLVLIVSGVVGCVIILNFGGGYMGLMVFLIYLGGM 63

Query: 465 M-FFGLTLPNYLESNPGAINTGILEVDQILIVLLTTEMFVG 504
           M  FG T    +E  P A  +G   V+ ++ VL+   M VG
Sbjct: 64  MVVFGYTTAMAIEEYPEAWGSG---VEVLVSVLVGLAMEVG 101


>gi|171543823 gamma-glutamyltransferase 6 isoform b [Homo sapiens]
          Length = 461

 Score = 30.0 bits (66), Expect = 6.3
 Identities = 25/81 (30%), Positives = 33/81 (40%), Gaps = 3/81 (3%)

Query: 348 APPPPVHAINRGIFTEGICCIIAGLLGTGNGSTSSSPNIGVLGITKVGSRRVVQYGAAIM 407
           APPP  H+   G++  G     AG +  G    SSS N   L     G  + +  G  + 
Sbjct: 92  APPPGGHSHGPGVYHHGAIISPAGAMFWGLFHDSSSGNSTAL---TSGPAQTLAPGLGLP 148

Query: 408 LVLGTIGKFTALFASLPDPIL 428
             L T+    A F  LP P L
Sbjct: 149 AALPTLHLLHARFGRLPWPRL 169


>gi|136255216 proline-rich transmembrane protein 3 [Homo sapiens]
          Length = 981

 Score = 29.6 bits (65), Expect = 8.3
 Identities = 45/196 (22%), Positives = 68/196 (34%), Gaps = 24/196 (12%)

Query: 278 PTDPKAYGFQARTDARGDIMAIAPWIRIPYPCQWGLPTVTAAAVLGMFSATLAGIIESIG 337
           P +P A    +   +     A AP      P +WG P     +          G++  + 
Sbjct: 433 PPEPTASSMASAPASSPPANATAP------PLRWG-PLRRVLSFSWELHVYGVGVLFLLP 485

Query: 338 DYYACARLAGAPPPPVHAINRGIFTEGICCIIAGLLGTGNGSTS---SSPNIGVLGITKV 394
              A A LA AP  P  A+        +  ++A  L +    T    S   +GV G    
Sbjct: 486 ALLALAALAAAPAGPRLAL-----VAAVLVLVASALRSAYMLTDPYGSQARLGVRG---- 536

Query: 395 GSRRVVQYGAAIMLVLGTIGKFT--ALFASLPDPILGGMFCTLFGMITAVGLSNLQFVDM 452
               +V Y     L+L  +   T   L A LP P+   +      ++  VGL     +  
Sbjct: 537 ---GLVLYNLPFPLLLTALAALTLLGLGAGLPPPLQNPLLLGAVALVHGVGLLATDLLST 593

Query: 453 NSSRNLFVLGFSMFFG 468
            S  NL   G S  +G
Sbjct: 594 WSVLNLLTQGLSCAWG 609


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.325    0.141    0.441 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 23,310,636
Number of Sequences: 37866
Number of extensions: 1049784
Number of successful extensions: 2831
Number of sequences better than 10.0: 11
Number of HSP's better than 10.0 without gapping: 7
Number of HSP's successfully gapped in prelim test: 4
Number of HSP's that attempted gapping in prelim test: 2811
Number of HSP's gapped (non-prelim): 14
length of query: 598
length of database: 18,247,518
effective HSP length: 108
effective length of query: 490
effective length of database: 14,157,990
effective search space: 6937415100
effective search space used: 6937415100
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.