Search of human proteins with 44680143

Search of human proteins with 44680143

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|44680143 solute carrier family 23 (nucleobase transporters),
member 1 isoform b [Homo sapiens]
         (602 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|44680143 solute carrier family 23 (nucleobase transporters), ...  1214   0.0  
gi|44680145 solute carrier family 23 (nucleobase transporters), ...  1200   0.0  
gi|44680148 solute carrier family 23 (nucleobase transporters), ...   780   0.0  
gi|40316845 solute carrier family 23 (nucleobase transporters), ...   780   0.0  
gi|222080105 solute carrier family 23 (nucleobase transporters),...   280   4e-75
gi|222080107 solute carrier family 23 (nucleobase transporters),...   273   4e-73
gi|158635944 solute carrier family 23 (nucleobase transporters),...    99   1e-20
gi|196123590 NADH dehydrogenase subunit 6 [Homo sapiens neandert...    35   0.15 
gi|251831118 NADH dehydrogenase subunit 6 [Homo sapiens]               35   0.15 
gi|171543823 gamma-glutamyltransferase 6 isoform b [Homo sapiens]      30   6.4  
gi|136255216 proline-rich transmembrane protein 3 [Homo sapiens]       30   8.3  

>gi|44680143 solute carrier family 23 (nucleobase transporters),
           member 1 isoform b [Homo sapiens]
          Length = 602

 Score = 1214 bits (3142), Expect = 0.0
 Identities = 602/602 (100%), Positives = 602/602 (100%)

Query: 1   MRAQEDLEGRTQHETTRDPSTPLPTEPKFDMLYKIEDVPPWYLCILLGFQHYLTCFSGTI 60
           MRAQEDLEGRTQHETTRDPSTPLPTEPKFDMLYKIEDVPPWYLCILLGFQHYLTCFSGTI
Sbjct: 1   MRAQEDLEGRTQHETTRDPSTPLPTEPKFDMLYKIEDVPPWYLCILLGFQHYLTCFSGTI 60

Query: 61  AVPFLLAEALCVGHDQHMVSQLIGTIFTCVGITTLIQTTVGIRLPLFQASAFAFLVPAKA 120
           AVPFLLAEALCVGHDQHMVSQLIGTIFTCVGITTLIQTTVGIRLPLFQASAFAFLVPAKA
Sbjct: 61  AVPFLLAEALCVGHDQHMVSQLIGTIFTCVGITTLIQTTVGIRLPLFQASAFAFLVPAKA 120

Query: 121 ILALERWKCPPEEEIYGNWSLPLNTSHIWHPRIREVGLHVQGAIMVSSVVEVVIGLLGLP 180
           ILALERWKCPPEEEIYGNWSLPLNTSHIWHPRIREVGLHVQGAIMVSSVVEVVIGLLGLP
Sbjct: 121 ILALERWKCPPEEEIYGNWSLPLNTSHIWHPRIREVGLHVQGAIMVSSVVEVVIGLLGLP 180

Query: 181 GALLNYIGPLTVTPTVSLIGLSVFQAAGDRAGSHWGISACSILLIILFSQYLRNLTFLLP 240
           GALLNYIGPLTVTPTVSLIGLSVFQAAGDRAGSHWGISACSILLIILFSQYLRNLTFLLP
Sbjct: 181 GALLNYIGPLTVTPTVSLIGLSVFQAAGDRAGSHWGISACSILLIILFSQYLRNLTFLLP 240

Query: 241 VYRWGKGLTLLRIQIFKMFPIMLAIMTVWLLCYVLTLTDVLPTDPKAYGFQARTDARGDI 300
           VYRWGKGLTLLRIQIFKMFPIMLAIMTVWLLCYVLTLTDVLPTDPKAYGFQARTDARGDI
Sbjct: 241 VYRWGKGLTLLRIQIFKMFPIMLAIMTVWLLCYVLTLTDVLPTDPKAYGFQARTDARGDI 300

Query: 301 MAIAPWIRIPYPCQWGLPTVTAAAVLGMFSATLAGIIESIGDYYACARLAGAPPPPVHAI 360
           MAIAPWIRIPYPCQWGLPTVTAAAVLGMFSATLAGIIESIGDYYACARLAGAPPPPVHAI
Sbjct: 301 MAIAPWIRIPYPCQWGLPTVTAAAVLGMFSATLAGIIESIGDYYACARLAGAPPPPVHAI 360

Query: 361 NRGIFTEGICCIIAGLLGTGNGSTSSSPNIGVLGITKVGSRRVVQYGAAIMLVLGTIGKF 420
           NRGIFTEGICCIIAGLLGTGNGSTSSSPNIGVLGITKVGSRRVVQYGAAIMLVLGTIGKF
Sbjct: 361 NRGIFTEGICCIIAGLLGTGNGSTSSSPNIGVLGITKVGSRRVVQYGAAIMLVLGTIGKF 420

Query: 421 TALFASLPDPILGGMFCTLFGMITAVGLSNLQFVDMNSSRNLFVLGFSMFFGLTLPNYLE 480
           TALFASLPDPILGGMFCTLFGMITAVGLSNLQFVDMNSSRNLFVLGFSMFFGLTLPNYLE
Sbjct: 421 TALFASLPDPILGGMFCTLFGMITAVGLSNLQFVDMNSSRNLFVLGFSMFFGLTLPNYLE 480

Query: 481 SNPGAINTGILEVDQILIVLLTTEMFVGGCLAFILDNTVPGSPEERGLIQWKAGAHANSD 540
           SNPGAINTGILEVDQILIVLLTTEMFVGGCLAFILDNTVPGSPEERGLIQWKAGAHANSD
Sbjct: 481 SNPGAINTGILEVDQILIVLLTTEMFVGGCLAFILDNTVPGSPEERGLIQWKAGAHANSD 540

Query: 541 MSSSLKSYDFPIGMGIVKRITFLKYIPICPVFKGFSSSSKDQIAIPEDTPENTETASVCT 600
           MSSSLKSYDFPIGMGIVKRITFLKYIPICPVFKGFSSSSKDQIAIPEDTPENTETASVCT
Sbjct: 541 MSSSLKSYDFPIGMGIVKRITFLKYIPICPVFKGFSSSSKDQIAIPEDTPENTETASVCT 600

Query: 601 KV 602
           KV
Sbjct: 601 KV 602


>gi|44680145 solute carrier family 23 (nucleobase transporters),
           member 1 isoform a [Homo sapiens]
          Length = 598

 Score = 1200 bits (3105), Expect = 0.0
 Identities = 598/602 (99%), Positives = 598/602 (99%), Gaps = 4/602 (0%)

Query: 1   MRAQEDLEGRTQHETTRDPSTPLPTEPKFDMLYKIEDVPPWYLCILLGFQHYLTCFSGTI 60
           MRAQEDLEGRTQHETTRDPSTPLPTEPKFDMLYKIEDVPPWYLCILLGFQHYLTCFSGTI
Sbjct: 1   MRAQEDLEGRTQHETTRDPSTPLPTEPKFDMLYKIEDVPPWYLCILLGFQHYLTCFSGTI 60

Query: 61  AVPFLLAEALCVGHDQHMVSQLIGTIFTCVGITTLIQTTVGIRLPLFQASAFAFLVPAKA 120
           AVPFLLAEALCVGHDQHMVSQLIGTIFTCVGITTLIQTTVGIRLPLFQASAFAFLVPAKA
Sbjct: 61  AVPFLLAEALCVGHDQHMVSQLIGTIFTCVGITTLIQTTVGIRLPLFQASAFAFLVPAKA 120

Query: 121 ILALERWKCPPEEEIYGNWSLPLNTSHIWHPRIREVGLHVQGAIMVSSVVEVVIGLLGLP 180
           ILALERWKCPPEEEIYGNWSLPLNTSHIWHPRIREV    QGAIMVSSVVEVVIGLLGLP
Sbjct: 121 ILALERWKCPPEEEIYGNWSLPLNTSHIWHPRIREV----QGAIMVSSVVEVVIGLLGLP 176

Query: 181 GALLNYIGPLTVTPTVSLIGLSVFQAAGDRAGSHWGISACSILLIILFSQYLRNLTFLLP 240
           GALLNYIGPLTVTPTVSLIGLSVFQAAGDRAGSHWGISACSILLIILFSQYLRNLTFLLP
Sbjct: 177 GALLNYIGPLTVTPTVSLIGLSVFQAAGDRAGSHWGISACSILLIILFSQYLRNLTFLLP 236

Query: 241 VYRWGKGLTLLRIQIFKMFPIMLAIMTVWLLCYVLTLTDVLPTDPKAYGFQARTDARGDI 300
           VYRWGKGLTLLRIQIFKMFPIMLAIMTVWLLCYVLTLTDVLPTDPKAYGFQARTDARGDI
Sbjct: 237 VYRWGKGLTLLRIQIFKMFPIMLAIMTVWLLCYVLTLTDVLPTDPKAYGFQARTDARGDI 296

Query: 301 MAIAPWIRIPYPCQWGLPTVTAAAVLGMFSATLAGIIESIGDYYACARLAGAPPPPVHAI 360
           MAIAPWIRIPYPCQWGLPTVTAAAVLGMFSATLAGIIESIGDYYACARLAGAPPPPVHAI
Sbjct: 297 MAIAPWIRIPYPCQWGLPTVTAAAVLGMFSATLAGIIESIGDYYACARLAGAPPPPVHAI 356

Query: 361 NRGIFTEGICCIIAGLLGTGNGSTSSSPNIGVLGITKVGSRRVVQYGAAIMLVLGTIGKF 420
           NRGIFTEGICCIIAGLLGTGNGSTSSSPNIGVLGITKVGSRRVVQYGAAIMLVLGTIGKF
Sbjct: 357 NRGIFTEGICCIIAGLLGTGNGSTSSSPNIGVLGITKVGSRRVVQYGAAIMLVLGTIGKF 416

Query: 421 TALFASLPDPILGGMFCTLFGMITAVGLSNLQFVDMNSSRNLFVLGFSMFFGLTLPNYLE 480
           TALFASLPDPILGGMFCTLFGMITAVGLSNLQFVDMNSSRNLFVLGFSMFFGLTLPNYLE
Sbjct: 417 TALFASLPDPILGGMFCTLFGMITAVGLSNLQFVDMNSSRNLFVLGFSMFFGLTLPNYLE 476

Query: 481 SNPGAINTGILEVDQILIVLLTTEMFVGGCLAFILDNTVPGSPEERGLIQWKAGAHANSD 540
           SNPGAINTGILEVDQILIVLLTTEMFVGGCLAFILDNTVPGSPEERGLIQWKAGAHANSD
Sbjct: 477 SNPGAINTGILEVDQILIVLLTTEMFVGGCLAFILDNTVPGSPEERGLIQWKAGAHANSD 536

Query: 541 MSSSLKSYDFPIGMGIVKRITFLKYIPICPVFKGFSSSSKDQIAIPEDTPENTETASVCT 600
           MSSSLKSYDFPIGMGIVKRITFLKYIPICPVFKGFSSSSKDQIAIPEDTPENTETASVCT
Sbjct: 537 MSSSLKSYDFPIGMGIVKRITFLKYIPICPVFKGFSSSSKDQIAIPEDTPENTETASVCT 596

Query: 601 KV 602
           KV
Sbjct: 597 KV 598


>gi|44680148 solute carrier family 23 (nucleobase transporters),
           member 2 [Homo sapiens]
          Length = 650

 Score =  780 bits (2014), Expect = 0.0
 Identities = 373/548 (68%), Positives = 449/548 (81%), Gaps = 7/548 (1%)

Query: 30  DMLYKIEDVPPWYLCILLGFQHYLTCFSGTIAVPFLLAEALCVGHDQHMVSQLIGTIFTC 89
           DM+Y IEDVPPWYLCI LG QHYLTCFSGTIAVPFLLA+A+CVG+DQ   SQLIGTIF C
Sbjct: 88  DMIYTIEDVPPWYLCIFLGLQHYLTCFSGTIAVPFLLADAMCVGYDQWATSQLIGTIFFC 147

Query: 90  VGITTLIQTTVGIRLPLFQASAFAFLVPAKAILALERWKCPPEEEIYGNWSLPL-NTSHI 148
           VGITTL+QTT G RLPLFQASAFAFL PA+AIL+L++WKC   +    N +  L +T HI
Sbjct: 148 VGITTLLQTTFGCRLPLFQASAFAFLAPARAILSLDKWKCNTTDVSVANGTAELLHTEHI 207

Query: 149 WHPRIREVGLHVQGAIMVSSVVEVVIGLLGLPGALLNYIGPLTVTPTVSLIGLSVFQAAG 208
           W+PRIRE+    QGAI++SS++EVVIGLLGLPGALL YIGPLT+TPTV+LIGLS FQAAG
Sbjct: 208 WYPRIREI----QGAIIMSSLIEVVIGLLGLPGALLKYIGPLTITPTVALIGLSGFQAAG 263

Query: 209 DRAGSHWGISACSILLIILFSQYLRNLTFLLPVYRWGKGLTLLRIQIFKMFPIMLAIMTV 268
           +RAG HWGI+  +I L++LFSQY RN+ F LP+Y+  KG T  ++Q+FKMFPI+LAI+  
Sbjct: 264 ERAGKHWGIAMLTIFLVLLFSQYARNVKFPLPIYKSKKGWTAYKLQLFKMFPIILAILVS 323

Query: 269 WLLCYVLTLTDVLPTDPKAYGFQARTDARGDIMAIAPWIRIPYPCQWGLPTVTAAAVLGM 328
           WLLC++ T+TDV P D   YGF ARTDAR  ++ +APW ++PYP QWGLPTV+AA V+GM
Sbjct: 324 WLLCFIFTVTDVFPPDSTKYGFYARTDARQGVLLVAPWFKVPYPFQWGLPTVSAAGVIGM 383

Query: 329 FSATLAGIIESIGDYYACARLAGAPPPPVHAINRGIFTEGICCIIAGLLGTGNGSTSSSP 388
            SA +A IIESIGDYYACARL+ APPPP+HAINRGIF EG+ C++ G+ GTGNGSTSSSP
Sbjct: 384 LSAVVASIIESIGDYYACARLSCAPPPPIHAINRGIFVEGLSCVLDGIFGTGNGSTSSSP 443

Query: 389 NIGVLGITKVGSRRVVQYGAAIMLVLGTIGKFTALFASLPDPILGGMFCTLFGMITAVGL 448
           NIGVLGITKVGSRRV+Q GAA+ML LG IGKF+ALFASLPDP+LG +FCTLFGMITAVGL
Sbjct: 444 NIGVLGITKVGSRRVIQCGAALMLALGMIGKFSALFASLPDPVLGALFCTLFGMITAVGL 503

Query: 449 SNLQFVDMNSSRNLFVLGFSMFFGLTLPNYLESNPGAINTGILEVDQILIVLLTTEMFVG 508
           SNLQF+D+NSSRNLFVLGFS+FFGL LP+YL  NP  + TGI  +DQ+L VLLTT MFVG
Sbjct: 504 SNLQFIDLNSSRNLFVLGFSIFFGLVLPSYLRQNP--LVTGITGIDQVLNVLLTTAMFVG 561

Query: 509 GCLAFILDNTVPGSPEERGLIQWKAGAHANSDMSSSLKSYDFPIGMGIVKRITFLKYIPI 568
           GC+AFILDNT+PG+PEERG+ +WK G    +     ++SY+ P GM I+K+     Y+PI
Sbjct: 562 GCVAFILDNTIPGTPEERGIRKWKKGVGKGNKSLDGMESYNLPFGMNIIKKYRCFSYLPI 621

Query: 569 CPVFKGFS 576
            P F G++
Sbjct: 622 SPTFVGYT 629


>gi|40316845 solute carrier family 23 (nucleobase transporters),
           member 2 [Homo sapiens]
          Length = 650

 Score =  780 bits (2014), Expect = 0.0
 Identities = 373/548 (68%), Positives = 449/548 (81%), Gaps = 7/548 (1%)

Query: 30  DMLYKIEDVPPWYLCILLGFQHYLTCFSGTIAVPFLLAEALCVGHDQHMVSQLIGTIFTC 89
           DM+Y IEDVPPWYLCI LG QHYLTCFSGTIAVPFLLA+A+CVG+DQ   SQLIGTIF C
Sbjct: 88  DMIYTIEDVPPWYLCIFLGLQHYLTCFSGTIAVPFLLADAMCVGYDQWATSQLIGTIFFC 147

Query: 90  VGITTLIQTTVGIRLPLFQASAFAFLVPAKAILALERWKCPPEEEIYGNWSLPL-NTSHI 148
           VGITTL+QTT G RLPLFQASAFAFL PA+AIL+L++WKC   +    N +  L +T HI
Sbjct: 148 VGITTLLQTTFGCRLPLFQASAFAFLAPARAILSLDKWKCNTTDVSVANGTAELLHTEHI 207

Query: 149 WHPRIREVGLHVQGAIMVSSVVEVVIGLLGLPGALLNYIGPLTVTPTVSLIGLSVFQAAG 208
           W+PRIRE+    QGAI++SS++EVVIGLLGLPGALL YIGPLT+TPTV+LIGLS FQAAG
Sbjct: 208 WYPRIREI----QGAIIMSSLIEVVIGLLGLPGALLKYIGPLTITPTVALIGLSGFQAAG 263

Query: 209 DRAGSHWGISACSILLIILFSQYLRNLTFLLPVYRWGKGLTLLRIQIFKMFPIMLAIMTV 268
           +RAG HWGI+  +I L++LFSQY RN+ F LP+Y+  KG T  ++Q+FKMFPI+LAI+  
Sbjct: 264 ERAGKHWGIAMLTIFLVLLFSQYARNVKFPLPIYKSKKGWTAYKLQLFKMFPIILAILVS 323

Query: 269 WLLCYVLTLTDVLPTDPKAYGFQARTDARGDIMAIAPWIRIPYPCQWGLPTVTAAAVLGM 328
           WLLC++ T+TDV P D   YGF ARTDAR  ++ +APW ++PYP QWGLPTV+AA V+GM
Sbjct: 324 WLLCFIFTVTDVFPPDSTKYGFYARTDARQGVLLVAPWFKVPYPFQWGLPTVSAAGVIGM 383

Query: 329 FSATLAGIIESIGDYYACARLAGAPPPPVHAINRGIFTEGICCIIAGLLGTGNGSTSSSP 388
            SA +A IIESIGDYYACARL+ APPPP+HAINRGIF EG+ C++ G+ GTGNGSTSSSP
Sbjct: 384 LSAVVASIIESIGDYYACARLSCAPPPPIHAINRGIFVEGLSCVLDGIFGTGNGSTSSSP 443

Query: 389 NIGVLGITKVGSRRVVQYGAAIMLVLGTIGKFTALFASLPDPILGGMFCTLFGMITAVGL 448
           NIGVLGITKVGSRRV+Q GAA+ML LG IGKF+ALFASLPDP+LG +FCTLFGMITAVGL
Sbjct: 444 NIGVLGITKVGSRRVIQCGAALMLALGMIGKFSALFASLPDPVLGALFCTLFGMITAVGL 503

Query: 449 SNLQFVDMNSSRNLFVLGFSMFFGLTLPNYLESNPGAINTGILEVDQILIVLLTTEMFVG 508
           SNLQF+D+NSSRNLFVLGFS+FFGL LP+YL  NP  + TGI  +DQ+L VLLTT MFVG
Sbjct: 504 SNLQFIDLNSSRNLFVLGFSIFFGLVLPSYLRQNP--LVTGITGIDQVLNVLLTTAMFVG 561

Query: 509 GCLAFILDNTVPGSPEERGLIQWKAGAHANSDMSSSLKSYDFPIGMGIVKRITFLKYIPI 568
           GC+AFILDNT+PG+PEERG+ +WK G    +     ++SY+ P GM I+K+     Y+PI
Sbjct: 562 GCVAFILDNTIPGTPEERGIRKWKKGVGKGNKSLDGMESYNLPFGMNIIKKYRCFSYLPI 621

Query: 569 CPVFKGFS 576
            P F G++
Sbjct: 622 SPTFVGYT 629


>gi|222080105 solute carrier family 23 (nucleobase transporters),
           member 3 isoform 2 [Homo sapiens]
          Length = 610

 Score =  280 bits (715), Expect = 4e-75
 Identities = 169/518 (32%), Positives = 270/518 (52%), Gaps = 30/518 (5%)

Query: 22  PLPTEPKFDMLYKIEDVPPWYLCILLGFQHYLTCFSGTIAVPFLLAEALCVGHDQHMVSQ 81
           P P  P       +    PW L  LL  QH L   S       LL  +L  G   +  SQ
Sbjct: 26  PAPQNPSTHSWDPLCGSLPWGLSCLLALQHVLVMASLLCVSHLLLLCSLSPGGLSYSPSQ 85

Query: 82  LIGTIFTCVGITTLIQTTVGIRLPLFQASAFAFLVPAKAILALERWKCPPEEEIYGNWSL 141
           L+ + F   G++T++QT +G RLPL QA +  FL+PA   L L   K P   +  GN SL
Sbjct: 86  LLASSFFSCGMSTILQTWMGSRLPLVQAPSLEFLIPA---LVLTSQKLPRAIQTPGNSSL 142

Query: 142 PLNTSH--------IWHPRIREVGLHVQGAIMVSSVVEVVIGLLGLPGALLNYIGPLTVT 193
            L+            W+  ++EV     GA++VS +++ ++GLLG PG +  + GPL + 
Sbjct: 143 MLHLCRGPSCHGLGHWNTSLQEVS----GAVVVSGLLQGMMGLLGSPGHVFPHCGPLVLA 198

Query: 194 PTVSLIGLSVFQAAGDRAGSHWGISACSILLIILFSQYLRNLTF-LLPVYRWGKGLTLLR 252
           P++ + GLS  +       +HWG++   ILL+++ SQ+L +  F + P  R     T   
Sbjct: 199 PSLVVAGLSAHREVAQFCFTHWGLALLVILLMVVCSQHLGSCQFHVCPWRRASTSSTHTP 258

Query: 253 IQIFKMFPIMLAIMTVWLLCYVLTLTDVLPTDPKAYGFQARTDARGDIMAIAPWIRIPYP 312
           + +F++  +++ +  VW++   +  + V+P +  A                APWI +P+P
Sbjct: 259 LPVFRLLSVLIPVACVWIVSAFVGFS-VIPQELSA-------------PTKAPWIWLPHP 304

Query: 313 CQWGLPTVTAAAVLGMFSATLAGIIESIGDYYACARLAGAPPPPVHAINRGIFTEGICCI 372
            +W  P +T  A+    S  LA    S+G Y  C RL   PPPP HA +RG+  EG+  +
Sbjct: 305 GEWNWPLLTPRALAAGISMALAASTSSLGCYALCGRLLHLPPPPPHACSRGLSLEGLGSV 364

Query: 373 IAGLLGTGNGSTSSSPNIGVLGITKVGSRRVVQYGAAIMLVLGTIGKFTALFASLPDPIL 432
           +AGLLG+  G+ SS PN+G +G+ + GS++V      + + LG   +   L  ++P P++
Sbjct: 365 LAGLLGSPMGTASSFPNVGKVGLIQAGSQQVAHLVGLLCVGLGLSPRLAQLLTTIPLPVV 424

Query: 433 GGMFCTLFGMITAVGLSNLQFVDMNSSRNLFVLGFSMFFGLTLPNYLESNPGAINTGILE 492
           GG+      ++ + G S+    D++S RN+F++GFS+F  L LP +    P   +TG   
Sbjct: 425 GGVLGVTQAVVLSAGFSSFYLADIDSGRNIFIVGFSIFMALLLPRWFREAPVLFSTGWSP 484

Query: 493 VDQILIVLLTTEMFVGGCLAFILDNTVPGSPEERGLIQ 530
           +D +L  LLT  +F+ G   F+L+NT+PG+  ERGL Q
Sbjct: 485 LDVLLHSLLTQPIFLAGLSGFLLENTIPGTQLERGLGQ 522


>gi|222080107 solute carrier family 23 (nucleobase transporters),
           member 3 isoform 3 [Homo sapiens]
          Length = 618

 Score =  273 bits (697), Expect = 4e-73
 Identities = 169/526 (32%), Positives = 270/526 (51%), Gaps = 38/526 (7%)

Query: 22  PLPTEPKFDMLYKIEDVPPWYLCILLGFQHYLTCFSGTIAVPFLLAEALCVGHDQHMVSQ 81
           P P  P       +    PW L  LL  QH L   S       LL  +L  G   +  SQ
Sbjct: 26  PAPQNPSTHSWDPLCGSLPWGLSCLLALQHVLVMASLLCVSHLLLLCSLSPGGLSYSPSQ 85

Query: 82  LIGTIFTCVGITTLIQTTVGIRLPLFQASAFAFLVPAKAILALERWKCPPEEEIYGNW-- 139
           L+ + F   G++T++QT +G RLPL QA +  FL+PA   L L   K P   +  GN   
Sbjct: 86  LLASSFFSCGMSTILQTWMGSRLPLVQAPSLEFLIPA---LVLTSQKLPRAIQTPGNCEH 142

Query: 140 ------SLPLNTSH--------IWHPRIREVGLHVQGAIMVSSVVEVVIGLLGLPGALLN 185
                 SL L+            W+  ++EV     GA++VS +++ ++GLLG PG +  
Sbjct: 143 RARARASLMLHLCRGPSCHGLGHWNTSLQEVS----GAVVVSGLLQGMMGLLGSPGHVFP 198

Query: 186 YIGPLTVTPTVSLIGLSVFQAAGDRAGSHWGISACSILLIILFSQYLRNLTF-LLPVYRW 244
           + GPL + P++ + GLS  +       +HWG++   ILL+++ SQ+L +  F + P  R 
Sbjct: 199 HCGPLVLAPSLVVAGLSAHREVAQFCFTHWGLALLVILLMVVCSQHLGSCQFHVCPWRRA 258

Query: 245 GKGLTLLRIQIFKMFPIMLAIMTVWLLCYVLTLTDVLPTDPKAYGFQARTDARGDIMAIA 304
               T   + +F++  +++ +  VW++   +  + V+P +  A                A
Sbjct: 259 STSSTHTPLPVFRLLSVLIPVACVWIVSAFVGFS-VIPQELSA-------------PTKA 304

Query: 305 PWIRIPYPCQWGLPTVTAAAVLGMFSATLAGIIESIGDYYACARLAGAPPPPVHAINRGI 364
           PWI +P+P +W  P +T  A+    S  LA    S+G Y  C RL   PPPP HA +RG+
Sbjct: 305 PWIWLPHPGEWNWPLLTPRALAAGISMALAASTSSLGCYALCGRLLHLPPPPPHACSRGL 364

Query: 365 FTEGICCIIAGLLGTGNGSTSSSPNIGVLGITKVGSRRVVQYGAAIMLVLGTIGKFTALF 424
             EG+  ++AGLLG+  G+ SS PN+G +G+ + GS++V      + + LG   +   L 
Sbjct: 365 SLEGLGSVLAGLLGSPMGTASSFPNVGKVGLIQAGSQQVAHLVGLLCVGLGLSPRLAQLL 424

Query: 425 ASLPDPILGGMFCTLFGMITAVGLSNLQFVDMNSSRNLFVLGFSMFFGLTLPNYLESNPG 484
            ++P P++GG+      ++ + G S+    D++S RN+F++GFS+F  L LP +    P 
Sbjct: 425 TTIPLPVVGGVLGVTQAVVLSAGFSSFYLADIDSGRNIFIVGFSIFMALLLPRWFREAPV 484

Query: 485 AINTGILEVDQILIVLLTTEMFVGGCLAFILDNTVPGSPEERGLIQ 530
             +TG   +D +L  LLT  +F+ G   F+L+NT+PG+  ERGL Q
Sbjct: 485 LFSTGWSPLDVLLHSLLTQPIFLAGLSGFLLENTIPGTQLERGLGQ 530


>gi|158635944 solute carrier family 23 (nucleobase transporters),
           member 3 isoform 1 [Homo sapiens]
          Length = 493

 Score = 99.0 bits (245), Expect = 1e-20
 Identities = 67/205 (32%), Positives = 101/205 (49%), Gaps = 15/205 (7%)

Query: 22  PLPTEPKFDMLYKIEDVPPWYLCILLGFQHYLTCFSGTIAVPFLLAEALCVGHDQHMVSQ 81
           P P  P       +    PW L  LL  QH L   S       LL  +L  G   +  SQ
Sbjct: 26  PAPQNPSTHSWDPLCGSLPWGLSCLLALQHVLVMASLLCVSHLLLLCSLSPGGLSYSPSQ 85

Query: 82  LIGTIFTCVGITTLIQTTVGIRLPLFQASAFAFLVPAKAILALERWKCPPEEEIYGNWSL 141
           L+ + F   G++T++QT +G RLPL QA +  FL+PA   L L   K P   +  GN SL
Sbjct: 86  LLASSFFSCGMSTILQTWMGSRLPLVQAPSLEFLIPA---LVLTSQKLPRAIQTPGNSSL 142

Query: 142 PLNTSH--------IWHPRIREVGLHVQGAIMVSSVVEVVIGLLGLPGALLNYIGPLTVT 193
            L+            W+  ++E    V GA++VS +++ ++GLLG PG +  + GPL + 
Sbjct: 143 MLHLCRGPSCHGLGHWNTSLQE----VSGAVVVSGLLQGMMGLLGSPGHVFPHCGPLVLA 198

Query: 194 PTVSLIGLSVFQAAGDRAGSHWGIS 218
           P++ + GLS  +       +HWG++
Sbjct: 199 PSLVVAGLSAHREVAQFCFTHWGLA 223



 Score = 94.4 bits (233), Expect = 3e-19
 Identities = 46/136 (33%), Positives = 78/136 (57%)

Query: 395 ITKVGSRRVVQYGAAIMLVLGTIGKFTALFASLPDPILGGMFCTLFGMITAVGLSNLQFV 454
           +T+ GS++V      + + LG   +   L  ++P P++GG+      ++ + G S+    
Sbjct: 270 LTQAGSQQVAHLVGLLCVGLGLSPRLAQLLTTIPLPVVGGVLGVTQAVVLSAGFSSFYLA 329

Query: 455 DMNSSRNLFVLGFSMFFGLTLPNYLESNPGAINTGILEVDQILIVLLTTEMFVGGCLAFI 514
           D++S RN+F++GFS+F  L LP +    P   +TG   +D +L  LLT  +F+ G   F+
Sbjct: 330 DIDSGRNIFIVGFSIFMALLLPRWFREAPVLFSTGWSPLDVLLHSLLTQPIFLAGLSGFL 389

Query: 515 LDNTVPGSPEERGLIQ 530
           L+NT+PG+  ERGL Q
Sbjct: 390 LENTIPGTQLERGLGQ 405


>gi|196123590 NADH dehydrogenase subunit 6 [Homo sapiens
           neanderthalensis]
          Length = 174

 Score = 35.4 bits (80), Expect = 0.15
 Identities = 32/101 (31%), Positives = 48/101 (47%), Gaps = 9/101 (8%)

Query: 409 AIMLVLGTIGKFTALFASLPDPILGGMFCTLFGMITAVGLSNLQFVDMNSSRNLFVLGFS 468
           ++ LV+G +G     F+S P PI GG+   + G++  V + N     M     L  LG  
Sbjct: 9   SVGLVMGFVG-----FSSKPSPIYGGLVLIVSGVVGCVIILNFGGGYMGLMVFLIYLGGM 63

Query: 469 M-FFGLTLPNYLESNPGAINTGILEVDQILIVLLTTEMFVG 508
           M  FG T    +E  P A  +G   V+ ++ VL+   M VG
Sbjct: 64  MVVFGYTTAMAIEEYPEAWGSG---VEVLVSVLVGLAMEVG 101


>gi|251831118 NADH dehydrogenase subunit 6 [Homo sapiens]
          Length = 174

 Score = 35.4 bits (80), Expect = 0.15
 Identities = 32/101 (31%), Positives = 48/101 (47%), Gaps = 9/101 (8%)

Query: 409 AIMLVLGTIGKFTALFASLPDPILGGMFCTLFGMITAVGLSNLQFVDMNSSRNLFVLGFS 468
           ++ LV+G +G     F+S P PI GG+   + G++  V + N     M     L  LG  
Sbjct: 9   SVGLVMGFVG-----FSSKPSPIYGGLVLIVSGVVGCVIILNFGGGYMGLMVFLIYLGGM 63

Query: 469 M-FFGLTLPNYLESNPGAINTGILEVDQILIVLLTTEMFVG 508
           M  FG T    +E  P A  +G   V+ ++ VL+   M VG
Sbjct: 64  MVVFGYTTAMAIEEYPEAWGSG---VEVLVSVLVGLAMEVG 101


>gi|171543823 gamma-glutamyltransferase 6 isoform b [Homo sapiens]
          Length = 461

 Score = 30.0 bits (66), Expect = 6.4
 Identities = 25/81 (30%), Positives = 33/81 (40%), Gaps = 3/81 (3%)

Query: 352 APPPPVHAINRGIFTEGICCIIAGLLGTGNGSTSSSPNIGVLGITKVGSRRVVQYGAAIM 411
           APPP  H+   G++  G     AG +  G    SSS N   L     G  + +  G  + 
Sbjct: 92  APPPGGHSHGPGVYHHGAIISPAGAMFWGLFHDSSSGNSTAL---TSGPAQTLAPGLGLP 148

Query: 412 LVLGTIGKFTALFASLPDPIL 432
             L T+    A F  LP P L
Sbjct: 149 AALPTLHLLHARFGRLPWPRL 169


>gi|136255216 proline-rich transmembrane protein 3 [Homo sapiens]
          Length = 981

 Score = 29.6 bits (65), Expect = 8.3
 Identities = 45/196 (22%), Positives = 68/196 (34%), Gaps = 24/196 (12%)

Query: 282 PTDPKAYGFQARTDARGDIMAIAPWIRIPYPCQWGLPTVTAAAVLGMFSATLAGIIESIG 341
           P +P A    +   +     A AP      P +WG P     +          G++  + 
Sbjct: 433 PPEPTASSMASAPASSPPANATAP------PLRWG-PLRRVLSFSWELHVYGVGVLFLLP 485

Query: 342 DYYACARLAGAPPPPVHAINRGIFTEGICCIIAGLLGTGNGSTS---SSPNIGVLGITKV 398
              A A LA AP  P  A+        +  ++A  L +    T    S   +GV G    
Sbjct: 486 ALLALAALAAAPAGPRLAL-----VAAVLVLVASALRSAYMLTDPYGSQARLGVRG---- 536

Query: 399 GSRRVVQYGAAIMLVLGTIGKFT--ALFASLPDPILGGMFCTLFGMITAVGLSNLQFVDM 456
               +V Y     L+L  +   T   L A LP P+   +      ++  VGL     +  
Sbjct: 537 ---GLVLYNLPFPLLLTALAALTLLGLGAGLPPPLQNPLLLGAVALVHGVGLLATDLLST 593

Query: 457 NSSRNLFVLGFSMFFG 472
            S  NL   G S  +G
Sbjct: 594 WSVLNLLTQGLSCAWG 609


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.325    0.141    0.441 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 23,484,410
Number of Sequences: 37866
Number of extensions: 1060472
Number of successful extensions: 2844
Number of sequences better than 10.0: 11
Number of HSP's better than 10.0 without gapping: 7
Number of HSP's successfully gapped in prelim test: 4
Number of HSP's that attempted gapping in prelim test: 2820
Number of HSP's gapped (non-prelim): 14
length of query: 602
length of database: 18,247,518
effective HSP length: 108
effective length of query: 494
effective length of database: 14,157,990
effective search space: 6994047060
effective search space used: 6994047060
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.