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Search of human proteins with 42734430
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|42734430 polymerase I and transcript release factor [Homo
sapiens]
(390 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|42734430 polymerase I and transcript release factor [Homo sap... 743 0.0
gi|4759082 serum deprivation response protein [Homo sapiens] 217 2e-56
gi|66472922 muscle-related coiled-coil protein [Homo sapiens] 170 2e-42
gi|47132587 protein kinase C, delta binding protein [Homo sapiens] 103 3e-22
gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Ho... 54 3e-07
gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Ho... 54 3e-07
gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Ho... 54 3e-07
gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Ho... 54 3e-07
gi|156104908 myosin heavy chain 6 [Homo sapiens] 52 7e-07
gi|42794779 myosin 18A isoform b [Homo sapiens] 51 2e-06
gi|28416946 myosin 18A isoform a [Homo sapiens] 51 2e-06
gi|116284396 myosin, heavy chain 14 isoform 1 [Homo sapiens] 50 3e-06
gi|116284394 myosin, heavy chain 14 isoform 2 [Homo sapiens] 50 3e-06
gi|224831241 myosin, heavy chain 14 isoform 3 [Homo sapiens] 50 3e-06
gi|217272804 hyaluronan-mediated motility receptor isoform d [Ho... 49 8e-06
gi|217272802 hyaluronan-mediated motility receptor isoform a [Ho... 49 8e-06
gi|217416398 hyaluronan-mediated motility receptor isoform c [Ho... 49 8e-06
gi|217416394 hyaluronan-mediated motility receptor isoform b [Ho... 49 8e-06
gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin ... 49 8e-06
gi|110624781 myosin, heavy polypeptide 13, skeletal muscle [Homo... 49 1e-05
gi|115496169 myosin, heavy chain 7, cardiac muscle, beta [Homo s... 48 2e-05
gi|153791497 ciliary rootlet coiled-coil [Homo sapiens] 48 2e-05
gi|110611903 myosin, heavy polypeptide 4, skeletal muscle [Homo ... 48 2e-05
gi|115298682 HBxAg transactivated protein 2 [Homo sapiens] 47 3e-05
gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens] 46 5e-05
gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens] 46 7e-05
gi|153791586 myosin, heavy chain 2, skeletal muscle, adult [Homo... 46 7e-05
gi|153792663 myosin, heavy chain 2, skeletal muscle, adult [Homo... 46 7e-05
gi|110815815 centlein isoform 1 [Homo sapiens] 46 7e-05
gi|156766047 GRB10 interacting GYF protein 2 isoform c [Homo sap... 45 9e-05
>gi|42734430 polymerase I and transcript release factor [Homo
sapiens]
Length = 390
Score = 743 bits (1918), Expect = 0.0
Identities = 390/390 (100%), Positives = 390/390 (100%)
Query: 1 MEDPTLYIVERPLPGYPDAEAPEPSSAGAQAAEEPSGAGSEELIKSDQVNGVLVLSLLDK 60
MEDPTLYIVERPLPGYPDAEAPEPSSAGAQAAEEPSGAGSEELIKSDQVNGVLVLSLLDK
Sbjct: 1 MEDPTLYIVERPLPGYPDAEAPEPSSAGAQAAEEPSGAGSEELIKSDQVNGVLVLSLLDK 60
Query: 61 IIGAVDQIQLTQAQLEERQAEMEGAVQSIQGELSKLGKAHATTSNTVSKLLEKVRKVSVN 120
IIGAVDQIQLTQAQLEERQAEMEGAVQSIQGELSKLGKAHATTSNTVSKLLEKVRKVSVN
Sbjct: 61 IIGAVDQIQLTQAQLEERQAEMEGAVQSIQGELSKLGKAHATTSNTVSKLLEKVRKVSVN 120
Query: 121 VKTVRGSLERQAGQIKKLEVNEAELLRRRNFKVMIYQDEVKLPAKLSISKSLKESEALPE 180
VKTVRGSLERQAGQIKKLEVNEAELLRRRNFKVMIYQDEVKLPAKLSISKSLKESEALPE
Sbjct: 121 VKTVRGSLERQAGQIKKLEVNEAELLRRRNFKVMIYQDEVKLPAKLSISKSLKESEALPE 180
Query: 181 KEGEELGEGERPEEDAAALELSSDEAVEVEEVIEESRAERIKRSGLRRVDDFKKAFSKEK 240
KEGEELGEGERPEEDAAALELSSDEAVEVEEVIEESRAERIKRSGLRRVDDFKKAFSKEK
Sbjct: 181 KEGEELGEGERPEEDAAALELSSDEAVEVEEVIEESRAERIKRSGLRRVDDFKKAFSKEK 240
Query: 241 MEKTKVRTRENLEKTRLKTKENLEKTRHTLEKRMNKLGTRLVPAERREKLKTSRDKLRKS 300
MEKTKVRTRENLEKTRLKTKENLEKTRHTLEKRMNKLGTRLVPAERREKLKTSRDKLRKS
Sbjct: 241 MEKTKVRTRENLEKTRLKTKENLEKTRHTLEKRMNKLGTRLVPAERREKLKTSRDKLRKS 300
Query: 301 FTPDHVVYARSKTAVYKVPPFTFHVKKIREGQVEVLKATEMVEVGADDDEGGAERGEAGD 360
FTPDHVVYARSKTAVYKVPPFTFHVKKIREGQVEVLKATEMVEVGADDDEGGAERGEAGD
Sbjct: 301 FTPDHVVYARSKTAVYKVPPFTFHVKKIREGQVEVLKATEMVEVGADDDEGGAERGEAGD 360
Query: 361 LRRGSSPDVHALLEITEESDAVLVDKSDSD 390
LRRGSSPDVHALLEITEESDAVLVDKSDSD
Sbjct: 361 LRRGSSPDVHALLEITEESDAVLVDKSDSD 390
>gi|4759082 serum deprivation response protein [Homo sapiens]
Length = 425
Score = 217 bits (552), Expect = 2e-56
Identities = 144/382 (37%), Positives = 215/382 (56%), Gaps = 63/382 (16%)
Query: 18 DAEAPEPSSAGAQAAEEPSGA----GSEELIKSD-QVNGVLVLSLLDKIIGAVDQIQLTQ 72
D +PSS + PS + +EE I+ + QVN V VL+LLDK++ +D +Q Q
Sbjct: 17 DMRQEKPSSPSPMPSSTPSPSLNLGNTEEAIRDNSQVNAVTVLTLLDKLVNMLDAVQENQ 76
Query: 73 AQLEERQAEMEGAVQSIQGELSKLGKAHATTSNTVSKLLEKVRKVSVNVKTVRGSLERQA 132
++E+RQ +EG+V+ IQ +L+KL K A+TSNTVSKLLEK RKVS + + V+ ++RQ
Sbjct: 77 HKMEQRQISLEGSVKGIQNDLTKLSKYQASTSNTVSKLLEKSRKVSAHTRAVKERMDRQC 136
Query: 133 GQIKKLEVNEAELLRRRNFKVMIYQDEVKLPA----KLSISKSLKESEALPEKEGEELGE 188
Q+K+LE N A+LLRR +FKV+I+Q+E ++PA K +S +++ E LP+ E
Sbjct: 137 AQVKRLENNHAQLLRRNHFKVLIFQEENEIPASVFVKQPVSGAVEGKEELPD-------E 189
Query: 189 GERPEEDAAALELSSD-------EAVE--VEEVIEESRAERIKRSGLRRVDDFKKAFSKE 239
+ EE ++LSSD EA+E EE +EESRAE+IKRS L++VD KKAFS++
Sbjct: 190 NKSLEETLHTVDLSSDDDLPHDEEALEDSAEEKVEESRAEKIKRSSLKKVDSLKKAFSRQ 249
Query: 240 KMEKTKVRTRENLEKTRLKTKENLEKTRHTLEKRMNKLGTRLVPAERREKLKTSRDKLRK 299
+EK+MNKLGT++V ERREK+K K
Sbjct: 250 -----------------------------NIEKKMNKLGTKIVSVERREKIK-------K 273
Query: 300 SFTPDHVVYARSKTAVYKVPPFTFHVKKIREGQVEVLKATEMVEVGADDDEGGAERGEAG 359
S T +H + K++ +KV P TF KK+REG+ T+ ++ + + + E+
Sbjct: 274 SLTSNHQKISSGKSSPFKVSPLTFGRKKVREGESHAENETKSEDLPSSEQMPNDQEEESF 333
Query: 360 DLRRGSSPDVHALL--EITEES 379
+ AL+ EI EE+
Sbjct: 334 AEGHSEASLASALVEGEIAEEA 355
>gi|66472922 muscle-related coiled-coil protein [Homo sapiens]
Length = 364
Score = 170 bits (431), Expect = 2e-42
Identities = 100/305 (32%), Positives = 173/305 (56%), Gaps = 39/305 (12%)
Query: 47 DQVNGVLVLSLLDKIIGAVDQIQLTQAQLEERQAEMEGAVQSIQGELSKLGKAHATTSNT 106
DQ + ++++LDK+ VD +Q +Q ++EER EME A++S+Q +L KL ++H+ T +
Sbjct: 26 DQDAALTIVTVLDKVASIVDSVQASQKRIEERHREMENAIKSVQIDLLKLSQSHSNTGHI 85
Query: 107 VSKLLEKVRKVSVNVKTVRGSLERQAGQIKKLEVNEAELLRRRNFKVMIYQDEVKLPAKL 166
++KL EK RKVS ++K V+ +E+Q +KK+EV + E++++ F+V+I+Q++ + P L
Sbjct: 86 INKLFEKTRKVSAHIKDVKARVEKQQIHVKKVEVKQEEIMKKNKFRVVIFQEKFRCPTSL 145
Query: 167 SISKSLKESEALPEKEGEELGEGERPEEDAAALELSSDEAVEVEEVIEESRAERIKRSGL 226
S+ K +E E + + ++LSSDE E +EESR+ R+++SG
Sbjct: 146 SVVKDRNLTENQEEDDDDIFDP---------PVDLSSDE----EYYVEESRSARLRKSGK 192
Query: 227 RRVDDFKKAFSKEKMEKTKVRTRENLEKTRLKTKENLEKTRHTLEKRMNKLGTRLVPAER 286
+D+ KKAFSKE N++KTR L+K++N++ TR+V ER
Sbjct: 193 EHIDNIKKAFSKE----------------------NMQKTRQNLDKKVNRIRTRIVTPER 230
Query: 287 REKLKTSRDKLRKSFTPDHVVYARSKTAVYKVPPF--TFHVKKIREGQVEVLKATEMV-- 342
RE+L+ S ++LR+S R K ++ P F ++ +R+G+ + E
Sbjct: 231 RERLRQSGERLRQSGERLRQSGERFKKSISNAAPSKEAFKMRSLRKGKDRTVAEGEECAR 290
Query: 343 EVGAD 347
E+G D
Sbjct: 291 EMGVD 295
>gi|47132587 protein kinase C, delta binding protein [Homo sapiens]
Length = 261
Score = 103 bits (256), Expect = 3e-22
Identities = 67/192 (34%), Positives = 110/192 (57%), Gaps = 14/192 (7%)
Query: 49 VNGVLVLSLLDKIIGAVDQIQLTQAQLEERQAEMEGAVQSIQGELSKLGKAHATTSNTVS 108
V+ V V++LL+K+ ++ ++ Q L RQ + G+V+ IQ L L ++H TTSNT++
Sbjct: 20 VHAVTVVTLLEKLASMLETLRERQGGLARRQGGLAGSVRRIQSGLGALSRSHDTTSNTLA 79
Query: 109 KLLEKVRKVSVNVKTVRGSLERQAGQIKKLEVNEAELLRRRNFKVMIYQDEVKLPAKLSI 168
+LL K +VS + + R+A Q+++LE N L+ R V+++++E ++PA
Sbjct: 80 QLLAKAERVSSHANAAQERAVRRAAQVQRLEANHGLLVARGKLHVLLFKEEGEVPA---- 135
Query: 169 SKSLKESEALPEKEGEELGEGERPEEDAAALELSSDEAVEVEEVIEESRAERIKRSGLRR 228
S K E L + ELG PE+ A + SSDE E V ESRA+R++R+GL++
Sbjct: 136 SAFQKAPEPLGPADQSELG----PEQLEAEVGESSDE----EPV--ESRAQRLRRTGLQK 185
Query: 229 VDDFKKAFSKEK 240
V ++A S K
Sbjct: 186 VQSLRRALSGRK 197
>gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Homo
sapiens]
Length = 1972
Score = 53.5 bits (127), Expect = 3e-07
Identities = 69/295 (23%), Positives = 131/295 (44%), Gaps = 28/295 (9%)
Query: 18 DAEAPEPSSAGAQAAEEPSGAGSEELIKSDQVNGVLVLSLLDK----IIGAVDQIQLTQA 73
+A+ E AQA EE + E K + N L+K + G + + +
Sbjct: 1191 EAQVQEMRQKHAQAVEELTE--QLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQ 1248
Query: 74 QLEERQAEMEGAVQSIQGELSKLGKAHATTSNTVSKLLEKVRKVSVNVKTVRGSLERQAG 133
++E ++ ++E VQ +Q + S +A A +L +KV K+ V++V G L G
Sbjct: 1249 EVEHKKKKLEAQVQELQSKCSDGERARA-------ELNDKVHKLQNEVESVTGMLNEAEG 1301
Query: 134 QIKKLEVNEAELLRRRNFKVMIYQDEVKLPAKLSISKSLKESE----ALPEKEGEELGEG 189
+ KL + A L + + Q+E + KL++S L++ E +L ++ EE+
Sbjct: 1302 KAIKLAKDVASLSSQLQDTQELLQEETR--QKLNVSTKLRQLEEERNSLQDQLDEEMEAK 1359
Query: 190 ERPEEDAAALELS-SDEAVEVEEVIEESRA-ERIKRSGLRRVDDF-----KKAFSKEKME 242
+ E + L + SD ++++ A E K+ + +++ +KA + +K+E
Sbjct: 1360 QNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLE 1419
Query: 243 KTKVRTRENLEKTRLKTKENLEKTRHTLEKRMNKLGTRLVPAER-REKLKTSRDK 296
KTK R ++ L+ + +N + LEK+ K L + K RD+
Sbjct: 1420 KTKNRLQQELDDL-VVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDR 1473
Score = 42.4 bits (98), Expect = 7e-04
Identities = 48/221 (21%), Positives = 95/221 (42%), Gaps = 27/221 (12%)
Query: 107 VSKLLEKVRKVSVNVKTVRGSLERQAGQIKKLEVNEAELLRRRNFKVMIYQDEVKLPAKL 166
V++ E+++ ++ + ++ ++K+LE ++L +N Q E +L A+
Sbjct: 847 VTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEA 906
Query: 167 S------ISKSLKESEALPEKEGEELGEGERPEEDAAALELSSDEAVEVEEVIEESRAER 220
+K + E L E E E +R ++ A + + + +++EE +EE A R
Sbjct: 907 EEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAAR 966
Query: 221 IK---------------RSGLRRVDDFKKAFSKEK--MEKTKVRTRENLEKTRLKTKENL 263
K + +DD SKE+ +E+ NL + K K NL
Sbjct: 967 QKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAK-NL 1025
Query: 264 EKTRHTLEKRMNKLGTRLVPAERREKLKTSRDKLRKSFTPD 304
K ++ E +++L RL ++ EK + +KL++ D
Sbjct: 1026 TKLKNKHESMISELEVRL---KKEEKSRQELEKLKRKLEGD 1063
Score = 40.0 bits (92), Expect = 0.004
Identities = 50/234 (21%), Positives = 100/234 (42%), Gaps = 17/234 (7%)
Query: 66 DQIQLTQAQLEERQAEMEGAVQSIQGELSKLGKAHATTSNTVSKLLEKVRKVSVNVKTVR 125
+QI QAQ+ E + ++ + +Q L++L A +N L+K+R++ ++ ++
Sbjct: 1069 EQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNA----LKKIRELEGHISDLQ 1124
Query: 126 GSLERQAGQIKKLEVNEAELLRRRNFKVMIYQDEVKLPAKLSISKSLKESEALPEKEGEE 185
L+ + K E + +L +D + A ++ +E E K+
Sbjct: 1125 EDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKA-- 1182
Query: 186 LGEGERPEEDAAALELSSDEAVEVEEVIEESRAERIKRSGLRRVDDFKKAFSKEKMEKTK 245
L E R E A E+ A VEE+ E+ + ++ L + +K+ +EK
Sbjct: 1183 LDEETRSHE-AQVQEMRQKHAQAVEELTEQLEQFKRAKANLDK--------NKQTLEKEN 1233
Query: 246 VRTRENLEKTRLKTKENLEKTRHTLEKRMNKLGTRLVPAER-REKLKTSRDKLR 298
L + + K+ +E + LE ++ +L ++ ER R +L KL+
Sbjct: 1234 ADLAGEL-RVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQ 1286
Score = 32.0 bits (71), Expect = 0.98
Identities = 42/232 (18%), Positives = 106/232 (45%), Gaps = 15/232 (6%)
Query: 64 AVDQIQLTQAQLEERQAEMEGAVQSIQGELSKLGKAHATTSNTVSKLLEKVRKVSVNVKT 123
A+ Q++ QAQ+++ Q E+E A ++ + E+ K + + ++ L ++++
Sbjct: 1643 AIKQLRKLQAQMKDFQRELEDA-RASRDEIFATAKENEKKAKSLEADLMQLQE-----DL 1696
Query: 124 VRGSLERQAGQIKKLEVNEAELLRRRNFKVMIYQDEVKLPAKLS-ISKSLKES----EAL 178
R+ ++K E+ E EL + + + ++ +L A+++ + + L+E EA+
Sbjct: 1697 AAAERARKQADLEKEELAE-ELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAM 1755
Query: 179 PEKEGEELGEGERPEEDAAALELSSDEAVEVEEVIEESRAERIKRSGLRRVDDFKKAFSK 238
++ + + E+ + A ++ + + +E E RS L ++ K+ K
Sbjct: 1756 SDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKE--LRSKLHEMEGAVKSKFK 1813
Query: 239 EKMEKTKVRTRENLEKTRLKTKENLEKTRHTLEKRMNKLGTRLVPAERREKL 290
+ + + + E+ + +E T+ +L+++ KL L+ E K+
Sbjct: 1814 STIAALEAKIAQLEEQVEQEAREKQAATK-SLKQKDKKLKEILLQVEDERKM 1864
Score = 32.0 bits (71), Expect = 0.98
Identities = 41/173 (23%), Positives = 72/173 (41%), Gaps = 20/173 (11%)
Query: 56 SLLDKIIGAVDQIQLTQAQLEERQAEMEGAVQSIQGELSKLGKAHATTSNTVSKLLEKVR 115
S K A Q++ +L + EMEGAV+ SK A +++L E+V
Sbjct: 1778 STAQKNESARQQLERQNKELRSKLHEMEGAVK------SKFKSTIAALEAKIAQLEEQVE 1831
Query: 116 KVSVNVKTVRGSLERQAGQIKKLEVNEAELLRRRNFKVMIYQDEVKLPAKLSISKSLKES 175
+ + + SL+++ ++K++ LL+ + + M Q + + + K LK
Sbjct: 1832 QEAREKQAATKSLKQKDKKLKEI------LLQVEDERKMAEQYKEQAEKGNARVKQLKRQ 1885
Query: 176 EALPEKEGEELGEGERPEEDAAALELSSDEAVEVEEVIEESRAERIKRSGLRR 228
E+E + + R L+ DEA E E + R +S LRR
Sbjct: 1886 LEEAEEESQRINANRR------KLQRELDEATESNEAM--GREVNALKSKLRR 1930
>gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Homo
sapiens]
Length = 1979
Score = 53.5 bits (127), Expect = 3e-07
Identities = 69/295 (23%), Positives = 131/295 (44%), Gaps = 28/295 (9%)
Query: 18 DAEAPEPSSAGAQAAEEPSGAGSEELIKSDQVNGVLVLSLLDK----IIGAVDQIQLTQA 73
+A+ E AQA EE + E K + N L+K + G + + +
Sbjct: 1198 EAQVQEMRQKHAQAVEELTE--QLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQ 1255
Query: 74 QLEERQAEMEGAVQSIQGELSKLGKAHATTSNTVSKLLEKVRKVSVNVKTVRGSLERQAG 133
++E ++ ++E VQ +Q + S +A A +L +KV K+ V++V G L G
Sbjct: 1256 EVEHKKKKLEAQVQELQSKCSDGERARA-------ELNDKVHKLQNEVESVTGMLNEAEG 1308
Query: 134 QIKKLEVNEAELLRRRNFKVMIYQDEVKLPAKLSISKSLKESE----ALPEKEGEELGEG 189
+ KL + A L + + Q+E + KL++S L++ E +L ++ EE+
Sbjct: 1309 KAIKLAKDVASLSSQLQDTQELLQEETR--QKLNVSTKLRQLEEERNSLQDQLDEEMEAK 1366
Query: 190 ERPEEDAAALELS-SDEAVEVEEVIEESRA-ERIKRSGLRRVDDF-----KKAFSKEKME 242
+ E + L + SD ++++ A E K+ + +++ +KA + +K+E
Sbjct: 1367 QNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLE 1426
Query: 243 KTKVRTRENLEKTRLKTKENLEKTRHTLEKRMNKLGTRLVPAER-REKLKTSRDK 296
KTK R ++ L+ + +N + LEK+ K L + K RD+
Sbjct: 1427 KTKNRLQQELDDL-VVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDR 1480
Score = 42.4 bits (98), Expect = 7e-04
Identities = 48/221 (21%), Positives = 95/221 (42%), Gaps = 27/221 (12%)
Query: 107 VSKLLEKVRKVSVNVKTVRGSLERQAGQIKKLEVNEAELLRRRNFKVMIYQDEVKLPAKL 166
V++ E+++ ++ + ++ ++K+LE ++L +N Q E +L A+
Sbjct: 854 VTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEA 913
Query: 167 S------ISKSLKESEALPEKEGEELGEGERPEEDAAALELSSDEAVEVEEVIEESRAER 220
+K + E L E E E +R ++ A + + + +++EE +EE A R
Sbjct: 914 EEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAAR 973
Query: 221 IK---------------RSGLRRVDDFKKAFSKEK--MEKTKVRTRENLEKTRLKTKENL 263
K + +DD SKE+ +E+ NL + K K NL
Sbjct: 974 QKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAK-NL 1032
Query: 264 EKTRHTLEKRMNKLGTRLVPAERREKLKTSRDKLRKSFTPD 304
K ++ E +++L RL ++ EK + +KL++ D
Sbjct: 1033 TKLKNKHESMISELEVRL---KKEEKSRQELEKLKRKLEGD 1070
Score = 40.0 bits (92), Expect = 0.004
Identities = 50/234 (21%), Positives = 100/234 (42%), Gaps = 17/234 (7%)
Query: 66 DQIQLTQAQLEERQAEMEGAVQSIQGELSKLGKAHATTSNTVSKLLEKVRKVSVNVKTVR 125
+QI QAQ+ E + ++ + +Q L++L A +N L+K+R++ ++ ++
Sbjct: 1076 EQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNA----LKKIRELEGHISDLQ 1131
Query: 126 GSLERQAGQIKKLEVNEAELLRRRNFKVMIYQDEVKLPAKLSISKSLKESEALPEKEGEE 185
L+ + K E + +L +D + A ++ +E E K+
Sbjct: 1132 EDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKA-- 1189
Query: 186 LGEGERPEEDAAALELSSDEAVEVEEVIEESRAERIKRSGLRRVDDFKKAFSKEKMEKTK 245
L E R E A E+ A VEE+ E+ + ++ L + +K+ +EK
Sbjct: 1190 LDEETRSHE-AQVQEMRQKHAQAVEELTEQLEQFKRAKANLDK--------NKQTLEKEN 1240
Query: 246 VRTRENLEKTRLKTKENLEKTRHTLEKRMNKLGTRLVPAER-REKLKTSRDKLR 298
L + + K+ +E + LE ++ +L ++ ER R +L KL+
Sbjct: 1241 ADLAGEL-RVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQ 1293
Score = 32.0 bits (71), Expect = 0.98
Identities = 42/232 (18%), Positives = 106/232 (45%), Gaps = 15/232 (6%)
Query: 64 AVDQIQLTQAQLEERQAEMEGAVQSIQGELSKLGKAHATTSNTVSKLLEKVRKVSVNVKT 123
A+ Q++ QAQ+++ Q E+E A ++ + E+ K + + ++ L ++++
Sbjct: 1650 AIKQLRKLQAQMKDFQRELEDA-RASRDEIFATAKENEKKAKSLEADLMQLQE-----DL 1703
Query: 124 VRGSLERQAGQIKKLEVNEAELLRRRNFKVMIYQDEVKLPAKLS-ISKSLKES----EAL 178
R+ ++K E+ E EL + + + ++ +L A+++ + + L+E EA+
Sbjct: 1704 AAAERARKQADLEKEELAE-ELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAM 1762
Query: 179 PEKEGEELGEGERPEEDAAALELSSDEAVEVEEVIEESRAERIKRSGLRRVDDFKKAFSK 238
++ + + E+ + A ++ + + +E E RS L ++ K+ K
Sbjct: 1763 SDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKE--LRSKLHEMEGAVKSKFK 1820
Query: 239 EKMEKTKVRTRENLEKTRLKTKENLEKTRHTLEKRMNKLGTRLVPAERREKL 290
+ + + + E+ + +E T+ +L+++ KL L+ E K+
Sbjct: 1821 STIAALEAKIAQLEEQVEQEAREKQAATK-SLKQKDKKLKEILLQVEDERKM 1871
Score = 32.0 bits (71), Expect = 0.98
Identities = 41/173 (23%), Positives = 72/173 (41%), Gaps = 20/173 (11%)
Query: 56 SLLDKIIGAVDQIQLTQAQLEERQAEMEGAVQSIQGELSKLGKAHATTSNTVSKLLEKVR 115
S K A Q++ +L + EMEGAV+ SK A +++L E+V
Sbjct: 1785 STAQKNESARQQLERQNKELRSKLHEMEGAVK------SKFKSTIAALEAKIAQLEEQVE 1838
Query: 116 KVSVNVKTVRGSLERQAGQIKKLEVNEAELLRRRNFKVMIYQDEVKLPAKLSISKSLKES 175
+ + + SL+++ ++K++ LL+ + + M Q + + + K LK
Sbjct: 1839 QEAREKQAATKSLKQKDKKLKEI------LLQVEDERKMAEQYKEQAEKGNARVKQLKRQ 1892
Query: 176 EALPEKEGEELGEGERPEEDAAALELSSDEAVEVEEVIEESRAERIKRSGLRR 228
E+E + + R L+ DEA E E + R +S LRR
Sbjct: 1893 LEEAEEESQRINANRR------KLQRELDEATESNEAM--GREVNALKSKLRR 1937
>gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Homo
sapiens]
Length = 1945
Score = 53.5 bits (127), Expect = 3e-07
Identities = 69/295 (23%), Positives = 131/295 (44%), Gaps = 28/295 (9%)
Query: 18 DAEAPEPSSAGAQAAEEPSGAGSEELIKSDQVNGVLVLSLLDK----IIGAVDQIQLTQA 73
+A+ E AQA EE + E K + N L+K + G + + +
Sbjct: 1198 EAQVQEMRQKHAQAVEELTE--QLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQ 1255
Query: 74 QLEERQAEMEGAVQSIQGELSKLGKAHATTSNTVSKLLEKVRKVSVNVKTVRGSLERQAG 133
++E ++ ++E VQ +Q + S +A A +L +KV K+ V++V G L G
Sbjct: 1256 EVEHKKKKLEAQVQELQSKCSDGERARA-------ELNDKVHKLQNEVESVTGMLNEAEG 1308
Query: 134 QIKKLEVNEAELLRRRNFKVMIYQDEVKLPAKLSISKSLKESE----ALPEKEGEELGEG 189
+ KL + A L + + Q+E + KL++S L++ E +L ++ EE+
Sbjct: 1309 KAIKLAKDVASLSSQLQDTQELLQEETR--QKLNVSTKLRQLEEERNSLQDQLDEEMEAK 1366
Query: 190 ERPEEDAAALELS-SDEAVEVEEVIEESRA-ERIKRSGLRRVDDF-----KKAFSKEKME 242
+ E + L + SD ++++ A E K+ + +++ +KA + +K+E
Sbjct: 1367 QNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLE 1426
Query: 243 KTKVRTRENLEKTRLKTKENLEKTRHTLEKRMNKLGTRLVPAER-REKLKTSRDK 296
KTK R ++ L+ + +N + LEK+ K L + K RD+
Sbjct: 1427 KTKNRLQQELDDL-VVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDR 1480
Score = 42.4 bits (98), Expect = 7e-04
Identities = 48/221 (21%), Positives = 95/221 (42%), Gaps = 27/221 (12%)
Query: 107 VSKLLEKVRKVSVNVKTVRGSLERQAGQIKKLEVNEAELLRRRNFKVMIYQDEVKLPAKL 166
V++ E+++ ++ + ++ ++K+LE ++L +N Q E +L A+
Sbjct: 854 VTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEA 913
Query: 167 S------ISKSLKESEALPEKEGEELGEGERPEEDAAALELSSDEAVEVEEVIEESRAER 220
+K + E L E E E +R ++ A + + + +++EE +EE A R
Sbjct: 914 EEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAAR 973
Query: 221 IK---------------RSGLRRVDDFKKAFSKEK--MEKTKVRTRENLEKTRLKTKENL 263
K + +DD SKE+ +E+ NL + K K NL
Sbjct: 974 QKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAK-NL 1032
Query: 264 EKTRHTLEKRMNKLGTRLVPAERREKLKTSRDKLRKSFTPD 304
K ++ E +++L RL ++ EK + +KL++ D
Sbjct: 1033 TKLKNKHESMISELEVRL---KKEEKSRQELEKLKRKLEGD 1070
Score = 40.0 bits (92), Expect = 0.004
Identities = 50/234 (21%), Positives = 100/234 (42%), Gaps = 17/234 (7%)
Query: 66 DQIQLTQAQLEERQAEMEGAVQSIQGELSKLGKAHATTSNTVSKLLEKVRKVSVNVKTVR 125
+QI QAQ+ E + ++ + +Q L++L A +N L+K+R++ ++ ++
Sbjct: 1076 EQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNA----LKKIRELEGHISDLQ 1131
Query: 126 GSLERQAGQIKKLEVNEAELLRRRNFKVMIYQDEVKLPAKLSISKSLKESEALPEKEGEE 185
L+ + K E + +L +D + A ++ +E E K+
Sbjct: 1132 EDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKA-- 1189
Query: 186 LGEGERPEEDAAALELSSDEAVEVEEVIEESRAERIKRSGLRRVDDFKKAFSKEKMEKTK 245
L E R E A E+ A VEE+ E+ + ++ L + +K+ +EK
Sbjct: 1190 LDEETRSHE-AQVQEMRQKHAQAVEELTEQLEQFKRAKANLDK--------NKQTLEKEN 1240
Query: 246 VRTRENLEKTRLKTKENLEKTRHTLEKRMNKLGTRLVPAER-REKLKTSRDKLR 298
L + + K+ +E + LE ++ +L ++ ER R +L KL+
Sbjct: 1241 ADLAGEL-RVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQ 1293
Score = 32.0 bits (71), Expect = 0.98
Identities = 42/232 (18%), Positives = 106/232 (45%), Gaps = 15/232 (6%)
Query: 64 AVDQIQLTQAQLEERQAEMEGAVQSIQGELSKLGKAHATTSNTVSKLLEKVRKVSVNVKT 123
A+ Q++ QAQ+++ Q E+E A ++ + E+ K + + ++ L ++++
Sbjct: 1650 AIKQLRKLQAQMKDFQRELEDA-RASRDEIFATAKENEKKAKSLEADLMQLQE-----DL 1703
Query: 124 VRGSLERQAGQIKKLEVNEAELLRRRNFKVMIYQDEVKLPAKLS-ISKSLKES----EAL 178
R+ ++K E+ E EL + + + ++ +L A+++ + + L+E EA+
Sbjct: 1704 AAAERARKQADLEKEELAE-ELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAM 1762
Query: 179 PEKEGEELGEGERPEEDAAALELSSDEAVEVEEVIEESRAERIKRSGLRRVDDFKKAFSK 238
++ + + E+ + A ++ + + +E E RS L ++ K+ K
Sbjct: 1763 SDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKE--LRSKLHEMEGAVKSKFK 1820
Query: 239 EKMEKTKVRTRENLEKTRLKTKENLEKTRHTLEKRMNKLGTRLVPAERREKL 290
+ + + + E+ + +E T+ +L+++ KL L+ E K+
Sbjct: 1821 STIAALEAKIAQLEEQVEQEAREKQAATK-SLKQKDKKLKEILLQVEDERKM 1871
Score = 30.4 bits (67), Expect = 2.9
Identities = 36/158 (22%), Positives = 66/158 (41%), Gaps = 18/158 (11%)
Query: 56 SLLDKIIGAVDQIQLTQAQLEERQAEMEGAVQSIQGELSKLGKAHATTSNTVSKLLEKVR 115
S K A Q++ +L + EMEGAV+ SK A +++L E+V
Sbjct: 1785 STAQKNESARQQLERQNKELRSKLHEMEGAVK------SKFKSTIAALEAKIAQLEEQVE 1838
Query: 116 KVSVNVKTVRGSLERQAGQIKKLEVNEAELLRRRNFKVMIYQDEVKLPAKLSISKSLKES 175
+ + + SL+++ ++K++ LL+ + + M Q + + + K LK
Sbjct: 1839 QEAREKQAATKSLKQKDKKLKEI------LLQVEDERKMAEQYKEQAEKGNARVKQLKRQ 1892
Query: 176 EALPEKEGEELGEGERPEEDAAALELSSDEAVEVEEVI 213
E+E + + R L+ DEA E E +
Sbjct: 1893 LEEAEEESQRINANRR------KLQRELDEATESNEAM 1924
>gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Homo
sapiens]
Length = 1938
Score = 53.5 bits (127), Expect = 3e-07
Identities = 69/295 (23%), Positives = 131/295 (44%), Gaps = 28/295 (9%)
Query: 18 DAEAPEPSSAGAQAAEEPSGAGSEELIKSDQVNGVLVLSLLDK----IIGAVDQIQLTQA 73
+A+ E AQA EE + E K + N L+K + G + + +
Sbjct: 1191 EAQVQEMRQKHAQAVEELTE--QLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQ 1248
Query: 74 QLEERQAEMEGAVQSIQGELSKLGKAHATTSNTVSKLLEKVRKVSVNVKTVRGSLERQAG 133
++E ++ ++E VQ +Q + S +A A +L +KV K+ V++V G L G
Sbjct: 1249 EVEHKKKKLEAQVQELQSKCSDGERARA-------ELNDKVHKLQNEVESVTGMLNEAEG 1301
Query: 134 QIKKLEVNEAELLRRRNFKVMIYQDEVKLPAKLSISKSLKESE----ALPEKEGEELGEG 189
+ KL + A L + + Q+E + KL++S L++ E +L ++ EE+
Sbjct: 1302 KAIKLAKDVASLSSQLQDTQELLQEETR--QKLNVSTKLRQLEEERNSLQDQLDEEMEAK 1359
Query: 190 ERPEEDAAALELS-SDEAVEVEEVIEESRA-ERIKRSGLRRVDDF-----KKAFSKEKME 242
+ E + L + SD ++++ A E K+ + +++ +KA + +K+E
Sbjct: 1360 QNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLE 1419
Query: 243 KTKVRTRENLEKTRLKTKENLEKTRHTLEKRMNKLGTRLVPAER-REKLKTSRDK 296
KTK R ++ L+ + +N + LEK+ K L + K RD+
Sbjct: 1420 KTKNRLQQELDDL-VVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDR 1473
Score = 42.4 bits (98), Expect = 7e-04
Identities = 48/221 (21%), Positives = 95/221 (42%), Gaps = 27/221 (12%)
Query: 107 VSKLLEKVRKVSVNVKTVRGSLERQAGQIKKLEVNEAELLRRRNFKVMIYQDEVKLPAKL 166
V++ E+++ ++ + ++ ++K+LE ++L +N Q E +L A+
Sbjct: 847 VTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEA 906
Query: 167 S------ISKSLKESEALPEKEGEELGEGERPEEDAAALELSSDEAVEVEEVIEESRAER 220
+K + E L E E E +R ++ A + + + +++EE +EE A R
Sbjct: 907 EEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAAR 966
Query: 221 IK---------------RSGLRRVDDFKKAFSKEK--MEKTKVRTRENLEKTRLKTKENL 263
K + +DD SKE+ +E+ NL + K K NL
Sbjct: 967 QKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAK-NL 1025
Query: 264 EKTRHTLEKRMNKLGTRLVPAERREKLKTSRDKLRKSFTPD 304
K ++ E +++L RL ++ EK + +KL++ D
Sbjct: 1026 TKLKNKHESMISELEVRL---KKEEKSRQELEKLKRKLEGD 1063
Score = 40.0 bits (92), Expect = 0.004
Identities = 50/234 (21%), Positives = 100/234 (42%), Gaps = 17/234 (7%)
Query: 66 DQIQLTQAQLEERQAEMEGAVQSIQGELSKLGKAHATTSNTVSKLLEKVRKVSVNVKTVR 125
+QI QAQ+ E + ++ + +Q L++L A +N L+K+R++ ++ ++
Sbjct: 1069 EQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNA----LKKIRELEGHISDLQ 1124
Query: 126 GSLERQAGQIKKLEVNEAELLRRRNFKVMIYQDEVKLPAKLSISKSLKESEALPEKEGEE 185
L+ + K E + +L +D + A ++ +E E K+
Sbjct: 1125 EDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKA-- 1182
Query: 186 LGEGERPEEDAAALELSSDEAVEVEEVIEESRAERIKRSGLRRVDDFKKAFSKEKMEKTK 245
L E R E A E+ A VEE+ E+ + ++ L + +K+ +EK
Sbjct: 1183 LDEETRSHE-AQVQEMRQKHAQAVEELTEQLEQFKRAKANLDK--------NKQTLEKEN 1233
Query: 246 VRTRENLEKTRLKTKENLEKTRHTLEKRMNKLGTRLVPAER-REKLKTSRDKLR 298
L + + K+ +E + LE ++ +L ++ ER R +L KL+
Sbjct: 1234 ADLAGEL-RVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQ 1286
Score = 32.0 bits (71), Expect = 0.98
Identities = 42/232 (18%), Positives = 106/232 (45%), Gaps = 15/232 (6%)
Query: 64 AVDQIQLTQAQLEERQAEMEGAVQSIQGELSKLGKAHATTSNTVSKLLEKVRKVSVNVKT 123
A+ Q++ QAQ+++ Q E+E A ++ + E+ K + + ++ L ++++
Sbjct: 1643 AIKQLRKLQAQMKDFQRELEDA-RASRDEIFATAKENEKKAKSLEADLMQLQE-----DL 1696
Query: 124 VRGSLERQAGQIKKLEVNEAELLRRRNFKVMIYQDEVKLPAKLS-ISKSLKES----EAL 178
R+ ++K E+ E EL + + + ++ +L A+++ + + L+E EA+
Sbjct: 1697 AAAERARKQADLEKEELAE-ELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAM 1755
Query: 179 PEKEGEELGEGERPEEDAAALELSSDEAVEVEEVIEESRAERIKRSGLRRVDDFKKAFSK 238
++ + + E+ + A ++ + + +E E RS L ++ K+ K
Sbjct: 1756 SDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKE--LRSKLHEMEGAVKSKFK 1813
Query: 239 EKMEKTKVRTRENLEKTRLKTKENLEKTRHTLEKRMNKLGTRLVPAERREKL 290
+ + + + E+ + +E T+ +L+++ KL L+ E K+
Sbjct: 1814 STIAALEAKIAQLEEQVEQEAREKQAATK-SLKQKDKKLKEILLQVEDERKM 1864
Score = 30.4 bits (67), Expect = 2.9
Identities = 36/158 (22%), Positives = 66/158 (41%), Gaps = 18/158 (11%)
Query: 56 SLLDKIIGAVDQIQLTQAQLEERQAEMEGAVQSIQGELSKLGKAHATTSNTVSKLLEKVR 115
S K A Q++ +L + EMEGAV+ SK A +++L E+V
Sbjct: 1778 STAQKNESARQQLERQNKELRSKLHEMEGAVK------SKFKSTIAALEAKIAQLEEQVE 1831
Query: 116 KVSVNVKTVRGSLERQAGQIKKLEVNEAELLRRRNFKVMIYQDEVKLPAKLSISKSLKES 175
+ + + SL+++ ++K++ LL+ + + M Q + + + K LK
Sbjct: 1832 QEAREKQAATKSLKQKDKKLKEI------LLQVEDERKMAEQYKEQAEKGNARVKQLKRQ 1885
Query: 176 EALPEKEGEELGEGERPEEDAAALELSSDEAVEVEEVI 213
E+E + + R L+ DEA E E +
Sbjct: 1886 LEEAEEESQRINANRR------KLQRELDEATESNEAM 1917
>gi|156104908 myosin heavy chain 6 [Homo sapiens]
Length = 1939
Score = 52.4 bits (124), Expect = 7e-07
Identities = 66/289 (22%), Positives = 131/289 (45%), Gaps = 44/289 (15%)
Query: 44 IKSDQVNGVLVLSLLDKIIGAVDQIQLTQAQLEERQAEMEGAVQSIQGELSKLGKAHATT 103
++ D+VN + + K+ VD ++ + Q ++ + ++E A + ++G+L ++
Sbjct: 1014 VEEDKVNSLSKSKV--KLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDL 1071
Query: 104 SNTVSKLLEKVRKVSVNVKTVRGSLERQ---AGQI-KKLEVNEA-------ELLRRRNFK 152
N +L EK++K ++ +E + A Q+ KKL+ N+A EL R +
Sbjct: 1072 ENDKLQLEEKLKKKEFDINQQNSKIEDEQVLALQLQKKLKENQARIEELEEELEAERTAR 1131
Query: 153 VMIYQDEVKLPAKLSISKSLKE-SEALPEKEGE---ELGEGERPEEDAAALELSSDEAVE 208
+ + + +S+ L+E SE L E G ++ ++ E + + +EA
Sbjct: 1132 AKVEK------LRSDLSRELEEISERLEEAGGATSVQIEMNKKREAEFQKMRRDLEEATL 1185
Query: 209 VEEV----IEESRAERIKRSGLRRVDDFKKAFSKEKMEKTKVRTRENLEKTR------LK 258
E + + A+ + G ++D+ ++ K+K+EK K + L+ +K
Sbjct: 1186 QHEATAAALRKKHADSVAELG-EQIDNLQRV--KQKLEKEKSEFKLELDDVTSNMEQIIK 1242
Query: 259 TKENLEKTRHTLEKRMNKLGTRLVPAER--------REKLKTSRDKLRK 299
K NLEK TLE + N+ +L A+R R KL+T +L +
Sbjct: 1243 AKANLEKVSRTLEDQANEYRVKLEEAQRSLNDFTTQRAKLQTENGELAR 1291
Score = 38.9 bits (89), Expect = 0.008
Identities = 45/241 (18%), Positives = 102/241 (42%), Gaps = 13/241 (5%)
Query: 67 QIQLTQAQLEERQAEMEGAVQSIQGELSKLGKAHATTSNTVSKLLEKV----RKVSVNVK 122
++ + +LE+ +E++ + ++ L+K+ K T N V L E++ ++ K
Sbjct: 937 ELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTK 996
Query: 123 TVRGSLERQAGQIKKLEVNEAELLRRRNFKVMIYQDEVKLPAKLSISKSLKESEALPEKE 182
+ E + L+V E ++ KV + Q L L K ++ + +
Sbjct: 997 EKKALQEAHQQALDDLQVEEDKVNSLSKSKVKLEQQVDDLEGSLEQEKKVR----MDLER 1052
Query: 183 GEELGEGERPEEDAAALELSSDEAVEVEEVIEESRAERIKRSGLRRVDDFKKAFSKEKME 242
+ EG+ + ++L +D+ +++EE +++ + I + + D+ A +K
Sbjct: 1053 AKRKLEGDLKLTQESIMDLENDK-LQLEEKLKKKEFD-INQQNSKIEDEQVLALQLQKKL 1110
Query: 243 KTKVRTRENLE---KTRLKTKENLEKTRHTLEKRMNKLGTRLVPAERREKLKTSRDKLRK 299
K E LE + + +EK R L + + ++ RL A ++ +K R+
Sbjct: 1111 KENQARIEELEEELEAERTARAKVEKLRSDLSRELEEISERLEEAGGATSVQIEMNKKRE 1170
Query: 300 S 300
+
Sbjct: 1171 A 1171
Score = 32.3 bits (72), Expect = 0.75
Identities = 44/240 (18%), Positives = 99/240 (41%), Gaps = 9/240 (3%)
Query: 65 VDQIQLTQAQLEERQAEMEGAVQSIQGELSKLGKAHATTSNTVSKLLEKVRKVSVNVKTV 124
VD +Q + + E+ + ++G+L+++ + + ++ ++V+ + +K
Sbjct: 1596 VDSLQTSLDAETRSRNEVLRVKKKMEGDLNEMEIQLSHANRMAAEAQKQVKSLQSLLKDT 1655
Query: 125 RGSLERQAGQIKKLEVNEAELLRRRNFKVMIYQDEVKLPAKLSISKSLKESEALPEKEGE 184
+ L+ L+ N A + RR N ++ + + S+ L E E + E
Sbjct: 1656 QIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVVEQTERSRKLAEQELIETSERV 1715
Query: 185 ELGEGERPEEDAAALELSSDEAV---EVEEVIEESR-AERIKRSGLRRVDDFKKAFSKEK 240
+L + ++ SD EVEE ++E R AE + + + KE+
Sbjct: 1716 QLLHSQNTSLINQKKKMESDLTQLQSEVEEAVQECRNAEEKAKKAITDAAMMAEELKKEQ 1775
Query: 241 MEKTKV-RTRENLEKTRLKTKENLEKTRHTL----EKRMNKLGTRLVPAERREKLKTSRD 295
+ R ++N+E+T + L++ +K++ KL R+ E + + R+
Sbjct: 1776 DTSAHLERMKKNMEQTIKDLQHRLDEAEQIALKGGKKQLQKLEARVRELEGELEAEQKRN 1835
>gi|42794779 myosin 18A isoform b [Homo sapiens]
Length = 2039
Score = 50.8 bits (120), Expect = 2e-06
Identities = 42/161 (26%), Positives = 76/161 (47%), Gaps = 10/161 (6%)
Query: 74 QLEERQAEMEGAVQ---SIQGELSKLGKAHATTSNTVSKLLEKVRKVSVNVKTVRGSLER 130
QLEE+ ++ G Q S++ EL + + +++K+ +++R + VK L+
Sbjct: 1501 QLEEKDMDIAGFTQKVVSLEAELQDISSQESKDEASLAKVKKQLRDLEAKVKDQEEELDE 1560
Query: 131 QAGQIKKLEVN------EAELLRRRNFKVMIYQDEVKLPAKLSISKSLKESEALPEKEGE 184
QAG I+ LE E E +R+ + K M +DE A+ S K LK+ E E+E E
Sbjct: 1561 QAGTIQMLEQAKLRLEMEMERMRQTHSKEMESRDEEVEEARQSCQKKLKQMEVQLEEEYE 1620
Query: 185 ELGEGERPEEDAAALELSSDEAVEVEEVIEESRAER-IKRS 224
+ + R + + + + V + E R + +KR+
Sbjct: 1621 DKQKVLREKRELEGKLATLSDQVNRRDFESEKRLRKDLKRT 1661
Score = 44.3 bits (103), Expect = 2e-04
Identities = 53/268 (19%), Positives = 117/268 (43%), Gaps = 41/268 (15%)
Query: 40 SEELIKSDQVNGVLVLSLLDKIIGAVDQIQLTQAQLEERQAEMEGAVQSIQGELSKLGKA 99
SEE I++ + S L+K ++++L +LE R +E+ +
Sbjct: 1252 SEEQIRNKDEEIQQLRSKLEKAEKERNELRLNSDRLESRISELTSELTD----------- 1300
Query: 100 HATTSNTVSKLLE-------KVRKVSVNVKTVRGSLERQAGQIKKLEVNEAELLRRRNFK 152
T + S+LL+ + K ++T +L++Q ++ ++EV EA L+R
Sbjct: 1301 ERNTGESASQLLDAETAERLRAEKEMKELQTQYDALKKQM-EVMEMEVMEARLIRAAEIN 1359
Query: 153 VMIYQDEVKLPAKLSISKSLKESEALPEKEGEELGEGERPEEDAAALELSSDEAVEVEEV 212
+ D+ +L ++++E + ++ L+ ++ +EVE
Sbjct: 1360 GEVDDDDAGGEWRLKYERAVREVDFTKKR-----------------LQQEFEDKLEVE-- 1400
Query: 213 IEESRAERIKRSGLRRVDDFKKAFSKEKMEKTKVRTRENLEKTRLKTKENLEKTRHTLEK 272
++++ + +R G + D + + ++++K R L+ T+L E + H LEK
Sbjct: 1401 -QQNKRQLERRLGDLQADSEESQRALQQLKKKCQRLTAELQDTKLHL-EGQQVRNHELEK 1458
Query: 273 RMNKLGTRLVPA-ERREKLKTSRDKLRK 299
+ + + L A E ++ K R+KL++
Sbjct: 1459 KQRRFDSELSQAHEEAQREKLQREKLQR 1486
Score = 41.2 bits (95), Expect = 0.002
Identities = 41/185 (22%), Positives = 81/185 (43%), Gaps = 5/185 (2%)
Query: 57 LLDKIIGAVDQIQLTQAQLEERQAEMEGAVQSIQGELSKLGKAHATTSNTVSKLLEK--V 114
L+ K AV Q AQ+ + QA++E A + Q KL + +++K V
Sbjct: 1758 LMKKHKAAVAQASRDLAQINDLQAQLEEANKEKQELQEKLQALQSQVEFLEQSMVDKSLV 1817
Query: 115 RKVSVNVKTVRGSLERQAGQIKKLEVNEAELLRRRNFKVMIYQDEVKLPAKLSISKSLKE 174
+ ++ + LE + Q+K+LE + L + N + + + + ++ A+ + K
Sbjct: 1818 SRQEAKIRELETRLEFERTQVKRLESLASRL--KENMEKLTEERDQRIAAENREKEQNKR 1875
Query: 175 SEALPEKEGEELGEGERPEEDAAALELSSDEAVEVEEVIEESRAERIKRSGLRRVDDFKK 234
+ EE+GE R E +A+ + + +E E +S +K + +R+ D +
Sbjct: 1876 LQRQLRDTKEEMGELARKEAEASRKKHELEMDLESLEAANQSLQADLKLA-FKRIGDLQA 1934
Query: 235 AFSKE 239
A E
Sbjct: 1935 AIEDE 1939
Score = 33.9 bits (76), Expect = 0.26
Identities = 48/233 (20%), Positives = 111/233 (47%), Gaps = 21/233 (9%)
Query: 68 IQLTQAQLEERQAEMEGAVQSIQG--ELSKLGKAHATTSNTVSKLLEKVRKVSVNVKTVR 125
++ T+A L + Q ++ S E+++L + T + ++ + + V ++ +
Sbjct: 1658 LKRTKALLADAQLMLDHLKNSAPSKREIAQLKNQLEESEFTCAAAVKARKAMEVEIEDLH 1717
Query: 126 GSLERQAGQIKKLEVNEAELLRRRN-FKVMIYQDEVKLPAKLSISKSLKESEALPEKEGE 184
++ A LE + L R +N + + +D+ + ++ +K+ +A +
Sbjct: 1718 LQIDDIAKAKTALEEQLSRLQREKNEIQNRLEEDQEDM------NELMKKHKAAVAQASR 1771
Query: 185 ELGEGERPEEDAAALELSSDEAVEVEEVIE--ESRAERIKRSGLRRVDDFKKAFSKEKME 242
+L + + A LE ++ E E++E ++ +S+ E +++S VD K S+++ +
Sbjct: 1772 DLAQ---INDLQAQLEEANKEKQELQEKLQALQSQVEFLEQS---MVD--KSLVSRQEAK 1823
Query: 243 KTKVRTRENLEKTRLKTKENL-EKTRHTLEKRMNKLGTRLVPAERREKLKTSR 294
++ TR E+T++K E+L + + +EK + R+ AE REK + R
Sbjct: 1824 IRELETRLEFERTQVKRLESLASRLKENMEKLTEERDQRIA-AENREKEQNKR 1875
>gi|28416946 myosin 18A isoform a [Homo sapiens]
Length = 2054
Score = 50.8 bits (120), Expect = 2e-06
Identities = 42/161 (26%), Positives = 76/161 (47%), Gaps = 10/161 (6%)
Query: 74 QLEERQAEMEGAVQ---SIQGELSKLGKAHATTSNTVSKLLEKVRKVSVNVKTVRGSLER 130
QLEE+ ++ G Q S++ EL + + +++K+ +++R + VK L+
Sbjct: 1501 QLEEKDMDIAGFTQKVVSLEAELQDISSQESKDEASLAKVKKQLRDLEAKVKDQEEELDE 1560
Query: 131 QAGQIKKLEVN------EAELLRRRNFKVMIYQDEVKLPAKLSISKSLKESEALPEKEGE 184
QAG I+ LE E E +R+ + K M +DE A+ S K LK+ E E+E E
Sbjct: 1561 QAGTIQMLEQAKLRLEMEMERMRQTHSKEMESRDEEVEEARQSCQKKLKQMEVQLEEEYE 1620
Query: 185 ELGEGERPEEDAAALELSSDEAVEVEEVIEESRAER-IKRS 224
+ + R + + + + V + E R + +KR+
Sbjct: 1621 DKQKVLREKRELEGKLATLSDQVNRRDFESEKRLRKDLKRT 1661
Score = 44.3 bits (103), Expect = 2e-04
Identities = 53/268 (19%), Positives = 117/268 (43%), Gaps = 41/268 (15%)
Query: 40 SEELIKSDQVNGVLVLSLLDKIIGAVDQIQLTQAQLEERQAEMEGAVQSIQGELSKLGKA 99
SEE I++ + S L+K ++++L +LE R +E+ +
Sbjct: 1252 SEEQIRNKDEEIQQLRSKLEKAEKERNELRLNSDRLESRISELTSELTD----------- 1300
Query: 100 HATTSNTVSKLLE-------KVRKVSVNVKTVRGSLERQAGQIKKLEVNEAELLRRRNFK 152
T + S+LL+ + K ++T +L++Q ++ ++EV EA L+R
Sbjct: 1301 ERNTGESASQLLDAETAERLRAEKEMKELQTQYDALKKQM-EVMEMEVMEARLIRAAEIN 1359
Query: 153 VMIYQDEVKLPAKLSISKSLKESEALPEKEGEELGEGERPEEDAAALELSSDEAVEVEEV 212
+ D+ +L ++++E + ++ L+ ++ +EVE
Sbjct: 1360 GEVDDDDAGGEWRLKYERAVREVDFTKKR-----------------LQQEFEDKLEVE-- 1400
Query: 213 IEESRAERIKRSGLRRVDDFKKAFSKEKMEKTKVRTRENLEKTRLKTKENLEKTRHTLEK 272
++++ + +R G + D + + ++++K R L+ T+L E + H LEK
Sbjct: 1401 -QQNKRQLERRLGDLQADSEESQRALQQLKKKCQRLTAELQDTKLHL-EGQQVRNHELEK 1458
Query: 273 RMNKLGTRLVPA-ERREKLKTSRDKLRK 299
+ + + L A E ++ K R+KL++
Sbjct: 1459 KQRRFDSELSQAHEEAQREKLQREKLQR 1486
Score = 42.4 bits (98), Expect = 7e-04
Identities = 55/250 (22%), Positives = 107/250 (42%), Gaps = 17/250 (6%)
Query: 57 LLDKIIGAVDQIQLTQAQLEERQAEMEGAVQSIQGELSKLGKAHATTSNTVSKLLEK--V 114
L+ K AV Q AQ+ + QA++E A + Q KL + +++K V
Sbjct: 1758 LMKKHKAAVAQASRDLAQINDLQAQLEEANKEKQELQEKLQALQSQVEFLEQSMVDKSLV 1817
Query: 115 RKVSVNVKTVRGSLERQAGQIKKLEVNEAELLRRRNFKVMIYQDEVKLPAKLSISKSLKE 174
+ ++ + LE + Q+K+LE + L + N + + + + ++ A+ + K
Sbjct: 1818 SRQEAKIRELETRLEFERTQVKRLESLASRL--KENMEKLTEERDQRIAAENREKEQNKR 1875
Query: 175 SEALPEKEGEELGEGERPEEDAAALELSSDEAVEVEEVIEESRAERIKRSGLRRVDDFKK 234
+ EE+GE R E +A+ + + +E E +S +K + +R+ D +
Sbjct: 1876 LQRQLRDTKEEMGELARKEAEASRKKHELEMDLESLEAANQSLQADLKLA-FKRIGDLQA 1934
Query: 235 AFSKEKMEKTKVRTRENLEKTRLKTKENLEKTRHTLEKRMNKL-GTRLVPAERREKLKTS 293
A E + + EN + +L+ +KR NKL G V +E +++
Sbjct: 1935 AIEDE------MESDENEDLI-----NSLQDMVTKYQKRKNKLEGDSDVDSELEDRVDGV 1983
Query: 294 RDKLRKSFTP 303
+ L K+ P
Sbjct: 1984 KSWLSKNKGP 1993
Score = 33.9 bits (76), Expect = 0.26
Identities = 48/233 (20%), Positives = 111/233 (47%), Gaps = 21/233 (9%)
Query: 68 IQLTQAQLEERQAEMEGAVQSIQG--ELSKLGKAHATTSNTVSKLLEKVRKVSVNVKTVR 125
++ T+A L + Q ++ S E+++L + T + ++ + + V ++ +
Sbjct: 1658 LKRTKALLADAQLMLDHLKNSAPSKREIAQLKNQLEESEFTCAAAVKARKAMEVEIEDLH 1717
Query: 126 GSLERQAGQIKKLEVNEAELLRRRN-FKVMIYQDEVKLPAKLSISKSLKESEALPEKEGE 184
++ A LE + L R +N + + +D+ + ++ +K+ +A +
Sbjct: 1718 LQIDDIAKAKTALEEQLSRLQREKNEIQNRLEEDQEDM------NELMKKHKAAVAQASR 1771
Query: 185 ELGEGERPEEDAAALELSSDEAVEVEEVIE--ESRAERIKRSGLRRVDDFKKAFSKEKME 242
+L + + A LE ++ E E++E ++ +S+ E +++S VD K S+++ +
Sbjct: 1772 DLAQ---INDLQAQLEEANKEKQELQEKLQALQSQVEFLEQS---MVD--KSLVSRQEAK 1823
Query: 243 KTKVRTRENLEKTRLKTKENL-EKTRHTLEKRMNKLGTRLVPAERREKLKTSR 294
++ TR E+T++K E+L + + +EK + R+ AE REK + R
Sbjct: 1824 IRELETRLEFERTQVKRLESLASRLKENMEKLTEERDQRIA-AENREKEQNKR 1875
>gi|116284396 myosin, heavy chain 14 isoform 1 [Homo sapiens]
Length = 2003
Score = 50.4 bits (119), Expect = 3e-06
Identities = 59/258 (22%), Positives = 120/258 (46%), Gaps = 36/258 (13%)
Query: 65 VDQIQLTQAQLEERQAEMEGAVQSIQGELSKLGKAHATTSNTVSKLLEKVRKVSVNVKTV 124
+ +Q + + E+R+ +E +Q +QG +A A + EK+++ ++ V
Sbjct: 1265 LSSLQTARQEGEQRRRRLELQLQEVQGRAGDGERARAEAA-------EKLQRAQAELENV 1317
Query: 125 RGSLERQAGQI----KKLEVNEAELLRRRNFKVMIYQDEVKLPAKLSISKSLKESEALPE 180
G+L + K+L EA+L + + Q+E + AKL++ ++ EA
Sbjct: 1318 SGALNEAESKTIRLSKELSSTEAQLHDAQE----LLQEETR--AKLALGSRVRAMEA--- 1368
Query: 181 KEGEELGEGERPEEDAAALELSSDEAVEVEEVIEESRAERIKRSG-LRRVDDFKKAFSKE 239
E G E+ EE+AAA E + E + + E R + + +G L ++ ++ ++E
Sbjct: 1369 ---EAAGLREQLEEEAAARERAGRELQTAQAQLSEWRRRQEEEAGALEAGEEARRRAARE 1425
Query: 240 KMEKTKVRTRENLEKTRLKTKENLEKTRHTLEKRMNKLGTRLVPAERREKLKTSRDKLRK 299
+ T+ EKT +T + LE+ R L++ +L + E++ +L ++ +K ++
Sbjct: 1426 ----AEALTQRLAEKT--ETVDRLERGRRRLQQ---ELDDATMDLEQQRQLVSTLEKKQR 1476
Query: 300 SFTPDHVVYARSKTAVYK 317
F + A K AV +
Sbjct: 1477 KFDQ---LLAEEKAAVLR 1491
Score = 40.4 bits (93), Expect = 0.003
Identities = 62/270 (22%), Positives = 106/270 (39%), Gaps = 18/270 (6%)
Query: 53 LVLSLLDKIIGAVD----QIQLTQAQLEERQAEMEGAVQSIQGELSKLGKAHATTSNTVS 108
LV+S L+ +G + Q+Q + +L++ E+E +++ +G KL TT +
Sbjct: 947 LVVSELEARVGEEEECSRQMQTEKKRLQQHIQELEAHLEAEEGARQKLQLEKVTTEAKMK 1006
Query: 109 KLLEKV-------RKVSVNVKTVRGSLERQAGQIKKLEVNEAELLR-RRNFKVMIYQDEV 160
K E + K+S K + L + Q + E L + R ++ I E
Sbjct: 1007 KFEEDLLLLEDQNSKLSKERKLLEDRLAEFSSQAAEEEEKVKSLNKLRLKYEATIADMED 1066
Query: 161 KLPAKLSISKSLKESEALPEKEGEELGE-----GERPEEDAAALELSSDEAVEVEEVIEE 215
+L + + L++ + + E EL E +R EE A L +E E+
Sbjct: 1067 RLRKEEKGRQELEKLKRRLDGESSELQEQMVEQQQRAEELRAQLGRKEEELQAALARAED 1126
Query: 216 SRAERIKRSGLRRVDDFKKAFSKEKMEKTKVRTRENLEKTRLKTKENLEKTRHTLEKRMN 275
R + R A ++E +E +V R EK R E LE R LE ++
Sbjct: 1127 EGGARAQLLKSLREAQAALAEAQEDLESERV-ARTKAEKQRRDLGEELEALRGELEDTLD 1185
Query: 276 KLGTRLVPAERREKLKTSRDKLRKSFTPDH 305
+ +RE+ T K + T H
Sbjct: 1186 STNAQQELRSKREQEVTELKKTLEEETRIH 1215
Score = 38.5 bits (88), Expect = 0.010
Identities = 56/239 (23%), Positives = 106/239 (44%), Gaps = 34/239 (14%)
Query: 75 LEERQAEMEGAVQSIQGELSKLGKAHATTSNTVSKLLEKVRKVSVNVKTVRGSLERQAGQ 134
LE+R AE + ++ L K T++ + +++RK + + R G+
Sbjct: 1029 LEDRLAEFSSQAAEEEEKVKSLNKLRLKYEATIADMEDRLRKEEKGRQELEKLKRRLDGE 1088
Query: 135 IKKLEVNEAELLRR-RNFKVMIYQDEVKLPAKLS-----------ISKSLKESEALPEKE 182
+L+ E +R + + + E +L A L+ + KSL+E++A +
Sbjct: 1089 SSELQEQMVEQQQRAEELRAQLGRKEEELQAALARAEDEGGARAQLLKSLREAQAALAEA 1148
Query: 183 GEELGEGE---RPEEDAAALELSSD-EAV--EVEEVIEESRAERIKRSGL-RRVDDFKKA 235
E+L E E R + + +L + EA+ E+E+ ++ + A++ RS + V + KK
Sbjct: 1149 QEDL-ESERVARTKAEKQRRDLGEELEALRGELEDTLDSTNAQQELRSKREQEVTELKKT 1207
Query: 236 FSKE----KMEKTKVRTR---------ENLEKTRLKTKENLEKTRHTLEKRMNKLGTRL 281
+E + ++R R E LE+ R + K EKTR LE +++L L
Sbjct: 1208 LEEETRIHEAAVQELRQRHGQALGELAEQLEQAR-RGKGAWEKTRLALEAEVSELRAEL 1265
Score = 35.8 bits (81), Expect = 0.068
Identities = 67/317 (21%), Positives = 120/317 (37%), Gaps = 56/317 (17%)
Query: 59 DKIIGAVDQIQLTQAQLEERQAEMEGAVQSIQGELSKLGKAHATTSNTVSKLL-EKVRKV 117
D++ V L++A + E + ++EG + ++ EL + + S+LL ++ RK+
Sbjct: 1736 DEMADEVANGNLSKAAILEEKRQLEGRLGQLEEELEE--------EQSNSELLNDRYRKL 1787
Query: 118 SVNVKTVRGSLERQAGQIKKLEVNEAELLRRRNFKVMIYQDEVKLPAKLSISKSLKESEA 177
+ V+++ L + K E +L R + +
Sbjct: 1788 LLQVESLTTELSAERSFSAKAESGRQQLER--------------------------QIQE 1821
Query: 178 LPEKEGEE-LGEGERPEEDAAALELSSDEAVEVEEVIEESRAERIKRSGL-RRVDDFKKA 235
L + GEE G R + AALE + + EE +E+ ERI L RR + K
Sbjct: 1822 LRGRLGEEDAGARARHKMTIAALE---SKLAQAEEQLEQETRERILSGKLVRRAEKRLKE 1878
Query: 236 FSKEKMEKTKV--RTRENLEKTRLKTKENLEKTRHTLEKRMNKLGTRLVPAERREKLKTS 293
+ E+ +V + R+ LEK L+ K+ + E+ R E + S
Sbjct: 1879 VVLQVEEERRVADQLRDQLEKGNLRVKQLKRQLEEAEEEASRAQAGRRRLQRELEDVTES 1938
Query: 294 RDKLRKSFTPDHVVYARSKTAVYKVPPFTFHVKKIREGQVEVLKATEMVEVGADDDEGGA 353
+ + + T R P TF + +R +V + E V +D++ A
Sbjct: 1939 AESMNREVTTLRNRLRRG--------PLTFTTRTVR----QVFRLEE--GVASDEEAEEA 1984
Query: 354 ERGEAGDLRRGSSPDVH 370
+ G SP H
Sbjct: 1985 QPGSGPSPEPEGSPPAH 2001
Score = 29.6 bits (65), Expect = 4.9
Identities = 58/257 (22%), Positives = 112/257 (43%), Gaps = 37/257 (14%)
Query: 69 QLTQAQLEERQAEME-----GAVQSIQGELSKLGKAHATTSNTVSKLLEKVRKVSVNVKT 123
QL A++E + + A + ++GEL +L A+ + ++++RK+ +K
Sbjct: 1622 QLRDAEVERDEERKQRTLAVAARKKLEGELEELKAQMASAGQGKEEAVKQLRKMQAQMKE 1681
Query: 124 VRGSLE-----------RQAGQIKKLEVNEAELLRRR-------NFKVMIYQDEVKLPAK 165
+ +E + K+L+ EAE+LR + + QD ++ +
Sbjct: 1682 LWREVEETRTSREEIFSQNRESEKRLKGLEAEVLRLQEELAASDRARRQAQQDRDEMADE 1741
Query: 166 LSISKSLKESEALPEKEGEE--LGE-GERPEEDAAALELSSDE----AVEVEEVIEESRA 218
++ + +L ++ L EK E LG+ E EE+ + EL +D ++VE + E A
Sbjct: 1742 VA-NGNLSKAAILEEKRQLEGRLGQLEEELEEEQSNSELLNDRYRKLLLQVESLTTELSA 1800
Query: 219 ERI----KRSGLRRVD-DFKKAFSKEKMEKTKVRTRENLEKTRLKTKENLEKTRHTLEKR 273
ER SG ++++ ++ + E R R + L++K + + E R
Sbjct: 1801 ERSFSAKAESGRQQLERQIQELRGRLGEEDAGARARHKMTIAALESKLAQAEEQLEQETR 1860
Query: 274 MNKLGTRLV-PAERREK 289
L +LV AE+R K
Sbjct: 1861 ERILSGKLVRRAEKRLK 1877
>gi|116284394 myosin, heavy chain 14 isoform 2 [Homo sapiens]
Length = 1995
Score = 50.4 bits (119), Expect = 3e-06
Identities = 59/258 (22%), Positives = 120/258 (46%), Gaps = 36/258 (13%)
Query: 65 VDQIQLTQAQLEERQAEMEGAVQSIQGELSKLGKAHATTSNTVSKLLEKVRKVSVNVKTV 124
+ +Q + + E+R+ +E +Q +QG +A A + EK+++ ++ V
Sbjct: 1257 LSSLQTARQEGEQRRRRLELQLQEVQGRAGDGERARAEAA-------EKLQRAQAELENV 1309
Query: 125 RGSLERQAGQI----KKLEVNEAELLRRRNFKVMIYQDEVKLPAKLSISKSLKESEALPE 180
G+L + K+L EA+L + + Q+E + AKL++ ++ EA
Sbjct: 1310 SGALNEAESKTIRLSKELSSTEAQLHDAQE----LLQEETR--AKLALGSRVRAMEA--- 1360
Query: 181 KEGEELGEGERPEEDAAALELSSDEAVEVEEVIEESRAERIKRSG-LRRVDDFKKAFSKE 239
E G E+ EE+AAA E + E + + E R + + +G L ++ ++ ++E
Sbjct: 1361 ---EAAGLREQLEEEAAARERAGRELQTAQAQLSEWRRRQEEEAGALEAGEEARRRAARE 1417
Query: 240 KMEKTKVRTRENLEKTRLKTKENLEKTRHTLEKRMNKLGTRLVPAERREKLKTSRDKLRK 299
+ T+ EKT +T + LE+ R L++ +L + E++ +L ++ +K ++
Sbjct: 1418 ----AEALTQRLAEKT--ETVDRLERGRRRLQQ---ELDDATMDLEQQRQLVSTLEKKQR 1468
Query: 300 SFTPDHVVYARSKTAVYK 317
F + A K AV +
Sbjct: 1469 KFDQ---LLAEEKAAVLR 1483
Score = 40.4 bits (93), Expect = 0.003
Identities = 62/270 (22%), Positives = 106/270 (39%), Gaps = 18/270 (6%)
Query: 53 LVLSLLDKIIGAVD----QIQLTQAQLEERQAEMEGAVQSIQGELSKLGKAHATTSNTVS 108
LV+S L+ +G + Q+Q + +L++ E+E +++ +G KL TT +
Sbjct: 939 LVVSELEARVGEEEECSRQMQTEKKRLQQHIQELEAHLEAEEGARQKLQLEKVTTEAKMK 998
Query: 109 KLLEKV-------RKVSVNVKTVRGSLERQAGQIKKLEVNEAELLR-RRNFKVMIYQDEV 160
K E + K+S K + L + Q + E L + R ++ I E
Sbjct: 999 KFEEDLLLLEDQNSKLSKERKLLEDRLAEFSSQAAEEEEKVKSLNKLRLKYEATIADMED 1058
Query: 161 KLPAKLSISKSLKESEALPEKEGEELGE-----GERPEEDAAALELSSDEAVEVEEVIEE 215
+L + + L++ + + E EL E +R EE A L +E E+
Sbjct: 1059 RLRKEEKGRQELEKLKRRLDGESSELQEQMVEQQQRAEELRAQLGRKEEELQAALARAED 1118
Query: 216 SRAERIKRSGLRRVDDFKKAFSKEKMEKTKVRTRENLEKTRLKTKENLEKTRHTLEKRMN 275
R + R A ++E +E +V R EK R E LE R LE ++
Sbjct: 1119 EGGARAQLLKSLREAQAALAEAQEDLESERV-ARTKAEKQRRDLGEELEALRGELEDTLD 1177
Query: 276 KLGTRLVPAERREKLKTSRDKLRKSFTPDH 305
+ +RE+ T K + T H
Sbjct: 1178 STNAQQELRSKREQEVTELKKTLEEETRIH 1207
Score = 38.5 bits (88), Expect = 0.010
Identities = 56/239 (23%), Positives = 106/239 (44%), Gaps = 34/239 (14%)
Query: 75 LEERQAEMEGAVQSIQGELSKLGKAHATTSNTVSKLLEKVRKVSVNVKTVRGSLERQAGQ 134
LE+R AE + ++ L K T++ + +++RK + + R G+
Sbjct: 1021 LEDRLAEFSSQAAEEEEKVKSLNKLRLKYEATIADMEDRLRKEEKGRQELEKLKRRLDGE 1080
Query: 135 IKKLEVNEAELLRR-RNFKVMIYQDEVKLPAKLS-----------ISKSLKESEALPEKE 182
+L+ E +R + + + E +L A L+ + KSL+E++A +
Sbjct: 1081 SSELQEQMVEQQQRAEELRAQLGRKEEELQAALARAEDEGGARAQLLKSLREAQAALAEA 1140
Query: 183 GEELGEGE---RPEEDAAALELSSD-EAV--EVEEVIEESRAERIKRSGL-RRVDDFKKA 235
E+L E E R + + +L + EA+ E+E+ ++ + A++ RS + V + KK
Sbjct: 1141 QEDL-ESERVARTKAEKQRRDLGEELEALRGELEDTLDSTNAQQELRSKREQEVTELKKT 1199
Query: 236 FSKE----KMEKTKVRTR---------ENLEKTRLKTKENLEKTRHTLEKRMNKLGTRL 281
+E + ++R R E LE+ R + K EKTR LE +++L L
Sbjct: 1200 LEEETRIHEAAVQELRQRHGQALGELAEQLEQAR-RGKGAWEKTRLALEAEVSELRAEL 1257
Score = 35.8 bits (81), Expect = 0.068
Identities = 67/317 (21%), Positives = 120/317 (37%), Gaps = 56/317 (17%)
Query: 59 DKIIGAVDQIQLTQAQLEERQAEMEGAVQSIQGELSKLGKAHATTSNTVSKLL-EKVRKV 117
D++ V L++A + E + ++EG + ++ EL + + S+LL ++ RK+
Sbjct: 1728 DEMADEVANGNLSKAAILEEKRQLEGRLGQLEEELEE--------EQSNSELLNDRYRKL 1779
Query: 118 SVNVKTVRGSLERQAGQIKKLEVNEAELLRRRNFKVMIYQDEVKLPAKLSISKSLKESEA 177
+ V+++ L + K E +L R + +
Sbjct: 1780 LLQVESLTTELSAERSFSAKAESGRQQLER--------------------------QIQE 1813
Query: 178 LPEKEGEE-LGEGERPEEDAAALELSSDEAVEVEEVIEESRAERIKRSGL-RRVDDFKKA 235
L + GEE G R + AALE + + EE +E+ ERI L RR + K
Sbjct: 1814 LRGRLGEEDAGARARHKMTIAALE---SKLAQAEEQLEQETRERILSGKLVRRAEKRLKE 1870
Query: 236 FSKEKMEKTKV--RTRENLEKTRLKTKENLEKTRHTLEKRMNKLGTRLVPAERREKLKTS 293
+ E+ +V + R+ LEK L+ K+ + E+ R E + S
Sbjct: 1871 VVLQVEEERRVADQLRDQLEKGNLRVKQLKRQLEEAEEEASRAQAGRRRLQRELEDVTES 1930
Query: 294 RDKLRKSFTPDHVVYARSKTAVYKVPPFTFHVKKIREGQVEVLKATEMVEVGADDDEGGA 353
+ + + T R P TF + +R +V + E V +D++ A
Sbjct: 1931 AESMNREVTTLRNRLRRG--------PLTFTTRTVR----QVFRLEE--GVASDEEAEEA 1976
Query: 354 ERGEAGDLRRGSSPDVH 370
+ G SP H
Sbjct: 1977 QPGSGPSPEPEGSPPAH 1993
Score = 29.6 bits (65), Expect = 4.9
Identities = 58/257 (22%), Positives = 112/257 (43%), Gaps = 37/257 (14%)
Query: 69 QLTQAQLEERQAEME-----GAVQSIQGELSKLGKAHATTSNTVSKLLEKVRKVSVNVKT 123
QL A++E + + A + ++GEL +L A+ + ++++RK+ +K
Sbjct: 1614 QLRDAEVERDEERKQRTLAVAARKKLEGELEELKAQMASAGQGKEEAVKQLRKMQAQMKE 1673
Query: 124 VRGSLE-----------RQAGQIKKLEVNEAELLRRR-------NFKVMIYQDEVKLPAK 165
+ +E + K+L+ EAE+LR + + QD ++ +
Sbjct: 1674 LWREVEETRTSREEIFSQNRESEKRLKGLEAEVLRLQEELAASDRARRQAQQDRDEMADE 1733
Query: 166 LSISKSLKESEALPEKEGEE--LGE-GERPEEDAAALELSSDE----AVEVEEVIEESRA 218
++ + +L ++ L EK E LG+ E EE+ + EL +D ++VE + E A
Sbjct: 1734 VA-NGNLSKAAILEEKRQLEGRLGQLEEELEEEQSNSELLNDRYRKLLLQVESLTTELSA 1792
Query: 219 ERI----KRSGLRRVD-DFKKAFSKEKMEKTKVRTRENLEKTRLKTKENLEKTRHTLEKR 273
ER SG ++++ ++ + E R R + L++K + + E R
Sbjct: 1793 ERSFSAKAESGRQQLERQIQELRGRLGEEDAGARARHKMTIAALESKLAQAEEQLEQETR 1852
Query: 274 MNKLGTRLV-PAERREK 289
L +LV AE+R K
Sbjct: 1853 ERILSGKLVRRAEKRLK 1869
>gi|224831241 myosin, heavy chain 14 isoform 3 [Homo sapiens]
Length = 2036
Score = 50.4 bits (119), Expect = 3e-06
Identities = 59/258 (22%), Positives = 120/258 (46%), Gaps = 36/258 (13%)
Query: 65 VDQIQLTQAQLEERQAEMEGAVQSIQGELSKLGKAHATTSNTVSKLLEKVRKVSVNVKTV 124
+ +Q + + E+R+ +E +Q +QG +A A + EK+++ ++ V
Sbjct: 1298 LSSLQTARQEGEQRRRRLELQLQEVQGRAGDGERARAEAA-------EKLQRAQAELENV 1350
Query: 125 RGSLERQAGQI----KKLEVNEAELLRRRNFKVMIYQDEVKLPAKLSISKSLKESEALPE 180
G+L + K+L EA+L + + Q+E + AKL++ ++ EA
Sbjct: 1351 SGALNEAESKTIRLSKELSSTEAQLHDAQE----LLQEETR--AKLALGSRVRAMEA--- 1401
Query: 181 KEGEELGEGERPEEDAAALELSSDEAVEVEEVIEESRAERIKRSG-LRRVDDFKKAFSKE 239
E G E+ EE+AAA E + E + + E R + + +G L ++ ++ ++E
Sbjct: 1402 ---EAAGLREQLEEEAAARERAGRELQTAQAQLSEWRRRQEEEAGALEAGEEARRRAARE 1458
Query: 240 KMEKTKVRTRENLEKTRLKTKENLEKTRHTLEKRMNKLGTRLVPAERREKLKTSRDKLRK 299
+ T+ EKT +T + LE+ R L++ +L + E++ +L ++ +K ++
Sbjct: 1459 ----AEALTQRLAEKT--ETVDRLERGRRRLQQ---ELDDATMDLEQQRQLVSTLEKKQR 1509
Query: 300 SFTPDHVVYARSKTAVYK 317
F + A K AV +
Sbjct: 1510 KFDQ---LLAEEKAAVLR 1524
Score = 40.4 bits (93), Expect = 0.003
Identities = 62/270 (22%), Positives = 106/270 (39%), Gaps = 18/270 (6%)
Query: 53 LVLSLLDKIIGAVD----QIQLTQAQLEERQAEMEGAVQSIQGELSKLGKAHATTSNTVS 108
LV+S L+ +G + Q+Q + +L++ E+E +++ +G KL TT +
Sbjct: 980 LVVSELEARVGEEEECSRQMQTEKKRLQQHIQELEAHLEAEEGARQKLQLEKVTTEAKMK 1039
Query: 109 KLLEKV-------RKVSVNVKTVRGSLERQAGQIKKLEVNEAELLR-RRNFKVMIYQDEV 160
K E + K+S K + L + Q + E L + R ++ I E
Sbjct: 1040 KFEEDLLLLEDQNSKLSKERKLLEDRLAEFSSQAAEEEEKVKSLNKLRLKYEATIADMED 1099
Query: 161 KLPAKLSISKSLKESEALPEKEGEELGE-----GERPEEDAAALELSSDEAVEVEEVIEE 215
+L + + L++ + + E EL E +R EE A L +E E+
Sbjct: 1100 RLRKEEKGRQELEKLKRRLDGESSELQEQMVEQQQRAEELRAQLGRKEEELQAALARAED 1159
Query: 216 SRAERIKRSGLRRVDDFKKAFSKEKMEKTKVRTRENLEKTRLKTKENLEKTRHTLEKRMN 275
R + R A ++E +E +V R EK R E LE R LE ++
Sbjct: 1160 EGGARAQLLKSLREAQAALAEAQEDLESERV-ARTKAEKQRRDLGEELEALRGELEDTLD 1218
Query: 276 KLGTRLVPAERREKLKTSRDKLRKSFTPDH 305
+ +RE+ T K + T H
Sbjct: 1219 STNAQQELRSKREQEVTELKKTLEEETRIH 1248
Score = 38.5 bits (88), Expect = 0.010
Identities = 56/239 (23%), Positives = 106/239 (44%), Gaps = 34/239 (14%)
Query: 75 LEERQAEMEGAVQSIQGELSKLGKAHATTSNTVSKLLEKVRKVSVNVKTVRGSLERQAGQ 134
LE+R AE + ++ L K T++ + +++RK + + R G+
Sbjct: 1062 LEDRLAEFSSQAAEEEEKVKSLNKLRLKYEATIADMEDRLRKEEKGRQELEKLKRRLDGE 1121
Query: 135 IKKLEVNEAELLRR-RNFKVMIYQDEVKLPAKLS-----------ISKSLKESEALPEKE 182
+L+ E +R + + + E +L A L+ + KSL+E++A +
Sbjct: 1122 SSELQEQMVEQQQRAEELRAQLGRKEEELQAALARAEDEGGARAQLLKSLREAQAALAEA 1181
Query: 183 GEELGEGE---RPEEDAAALELSSD-EAV--EVEEVIEESRAERIKRSGL-RRVDDFKKA 235
E+L E E R + + +L + EA+ E+E+ ++ + A++ RS + V + KK
Sbjct: 1182 QEDL-ESERVARTKAEKQRRDLGEELEALRGELEDTLDSTNAQQELRSKREQEVTELKKT 1240
Query: 236 FSKE----KMEKTKVRTR---------ENLEKTRLKTKENLEKTRHTLEKRMNKLGTRL 281
+E + ++R R E LE+ R + K EKTR LE +++L L
Sbjct: 1241 LEEETRIHEAAVQELRQRHGQALGELAEQLEQAR-RGKGAWEKTRLALEAEVSELRAEL 1298
Score = 35.8 bits (81), Expect = 0.068
Identities = 67/317 (21%), Positives = 120/317 (37%), Gaps = 56/317 (17%)
Query: 59 DKIIGAVDQIQLTQAQLEERQAEMEGAVQSIQGELSKLGKAHATTSNTVSKLL-EKVRKV 117
D++ V L++A + E + ++EG + ++ EL + + S+LL ++ RK+
Sbjct: 1769 DEMADEVANGNLSKAAILEEKRQLEGRLGQLEEELEE--------EQSNSELLNDRYRKL 1820
Query: 118 SVNVKTVRGSLERQAGQIKKLEVNEAELLRRRNFKVMIYQDEVKLPAKLSISKSLKESEA 177
+ V+++ L + K E +L R + +
Sbjct: 1821 LLQVESLTTELSAERSFSAKAESGRQQLER--------------------------QIQE 1854
Query: 178 LPEKEGEE-LGEGERPEEDAAALELSSDEAVEVEEVIEESRAERIKRSGL-RRVDDFKKA 235
L + GEE G R + AALE + + EE +E+ ERI L RR + K
Sbjct: 1855 LRGRLGEEDAGARARHKMTIAALE---SKLAQAEEQLEQETRERILSGKLVRRAEKRLKE 1911
Query: 236 FSKEKMEKTKV--RTRENLEKTRLKTKENLEKTRHTLEKRMNKLGTRLVPAERREKLKTS 293
+ E+ +V + R+ LEK L+ K+ + E+ R E + S
Sbjct: 1912 VVLQVEEERRVADQLRDQLEKGNLRVKQLKRQLEEAEEEASRAQAGRRRLQRELEDVTES 1971
Query: 294 RDKLRKSFTPDHVVYARSKTAVYKVPPFTFHVKKIREGQVEVLKATEMVEVGADDDEGGA 353
+ + + T R P TF + +R +V + E V +D++ A
Sbjct: 1972 AESMNREVTTLRNRLRRG--------PLTFTTRTVR----QVFRLEE--GVASDEEAEEA 2017
Query: 354 ERGEAGDLRRGSSPDVH 370
+ G SP H
Sbjct: 2018 QPGSGPSPEPEGSPPAH 2034
Score = 29.6 bits (65), Expect = 4.9
Identities = 58/257 (22%), Positives = 112/257 (43%), Gaps = 37/257 (14%)
Query: 69 QLTQAQLEERQAEME-----GAVQSIQGELSKLGKAHATTSNTVSKLLEKVRKVSVNVKT 123
QL A++E + + A + ++GEL +L A+ + ++++RK+ +K
Sbjct: 1655 QLRDAEVERDEERKQRTLAVAARKKLEGELEELKAQMASAGQGKEEAVKQLRKMQAQMKE 1714
Query: 124 VRGSLE-----------RQAGQIKKLEVNEAELLRRR-------NFKVMIYQDEVKLPAK 165
+ +E + K+L+ EAE+LR + + QD ++ +
Sbjct: 1715 LWREVEETRTSREEIFSQNRESEKRLKGLEAEVLRLQEELAASDRARRQAQQDRDEMADE 1774
Query: 166 LSISKSLKESEALPEKEGEE--LGE-GERPEEDAAALELSSDE----AVEVEEVIEESRA 218
++ + +L ++ L EK E LG+ E EE+ + EL +D ++VE + E A
Sbjct: 1775 VA-NGNLSKAAILEEKRQLEGRLGQLEEELEEEQSNSELLNDRYRKLLLQVESLTTELSA 1833
Query: 219 ERI----KRSGLRRVD-DFKKAFSKEKMEKTKVRTRENLEKTRLKTKENLEKTRHTLEKR 273
ER SG ++++ ++ + E R R + L++K + + E R
Sbjct: 1834 ERSFSAKAESGRQQLERQIQELRGRLGEEDAGARARHKMTIAALESKLAQAEEQLEQETR 1893
Query: 274 MNKLGTRLV-PAERREK 289
L +LV AE+R K
Sbjct: 1894 ERILSGKLVRRAEKRLK 1910
>gi|217272804 hyaluronan-mediated motility receptor isoform d [Homo
sapiens]
Length = 638
Score = 48.9 bits (115), Expect = 8e-06
Identities = 69/291 (23%), Positives = 123/291 (42%), Gaps = 57/291 (19%)
Query: 40 SEELIKSDQVNGVLVLSLLDKIIGAVDQIQLTQAQLEERQAEMEGAVQSIQGELSKLGKA 99
S EL+K + ++ K G ++Q+TQ LEE Q G + ++G+L + K
Sbjct: 81 SLELMKLRNKRETKMRGMMAKQEGMEMKLQVTQRSLEESQ----GKIAQLEGKLVSIEKE 136
Query: 100 HATTSNTVSKLLEKVRKVSVNVKTVRGSLERQAGQIKKLEVNEAELLRRRNFKVMIYQDE 159
+ KLLE + ++S +E+ I +LE N L+ +N DE
Sbjct: 137 KIDEKSETEKLLEYIEEIS----CASDQVEKYKLDIAQLEEN----LKEKN-------DE 181
Query: 160 VKLPAKLSISKSLKESEALPEKEGEELGEG----ERPEEDAAALELSSDEAVEVEE---- 211
+ LS+ +SL+E+ + K+ E+L E+ +ED +E + E
Sbjct: 182 I-----LSLKQSLEENIVILSKQVEDLNVKCQLLEKEKEDHVNRNREHNENLNAEMQNLK 236
Query: 212 ---VIEESRAERIKRSGL-----------------RRVDDFKKAFSKEK--MEKTKVRTR 249
++E+ E++++ L +++ F++ KEK E+ +T
Sbjct: 237 QKFILEQQEREKLQQKELQIDSLLQQEKELSSSLHQKLCSFQEEMVKEKNLFEEELKQTL 296
Query: 250 ENLEKTRLKTKENLEKTRHTLEKRMNKLGTRLVPAERREKLKTSRDKLRKS 300
+ L+K + K +E E+ LE+ L E EKLK +L KS
Sbjct: 297 DELDKLQQK-EEQAERLVKQLEEEAKSRAEELKLLE--EKLKGKEAELEKS 344
>gi|217272802 hyaluronan-mediated motility receptor isoform a [Homo
sapiens]
Length = 725
Score = 48.9 bits (115), Expect = 8e-06
Identities = 69/291 (23%), Positives = 123/291 (42%), Gaps = 57/291 (19%)
Query: 40 SEELIKSDQVNGVLVLSLLDKIIGAVDQIQLTQAQLEERQAEMEGAVQSIQGELSKLGKA 99
S EL+K + ++ K G ++Q+TQ LEE Q G + ++G+L + K
Sbjct: 168 SLELMKLRNKRETKMRGMMAKQEGMEMKLQVTQRSLEESQ----GKIAQLEGKLVSIEKE 223
Query: 100 HATTSNTVSKLLEKVRKVSVNVKTVRGSLERQAGQIKKLEVNEAELLRRRNFKVMIYQDE 159
+ KLLE + ++S +E+ I +LE N L+ +N DE
Sbjct: 224 KIDEKSETEKLLEYIEEIS----CASDQVEKYKLDIAQLEEN----LKEKN-------DE 268
Query: 160 VKLPAKLSISKSLKESEALPEKEGEELGEG----ERPEEDAAALELSSDEAVEVEE---- 211
+ LS+ +SL+E+ + K+ E+L E+ +ED +E + E
Sbjct: 269 I-----LSLKQSLEENIVILSKQVEDLNVKCQLLEKEKEDHVNRNREHNENLNAEMQNLK 323
Query: 212 ---VIEESRAERIKRSGL-----------------RRVDDFKKAFSKEK--MEKTKVRTR 249
++E+ E++++ L +++ F++ KEK E+ +T
Sbjct: 324 QKFILEQQEREKLQQKELQIDSLLQQEKELSSSLHQKLCSFQEEMVKEKNLFEEELKQTL 383
Query: 250 ENLEKTRLKTKENLEKTRHTLEKRMNKLGTRLVPAERREKLKTSRDKLRKS 300
+ L+K + K +E E+ LE+ L E EKLK +L KS
Sbjct: 384 DELDKLQQK-EEQAERLVKQLEEEAKSRAEELKLLE--EKLKGKEAELEKS 431
>gi|217416398 hyaluronan-mediated motility receptor isoform c [Homo
sapiens]
Length = 709
Score = 48.9 bits (115), Expect = 8e-06
Identities = 69/291 (23%), Positives = 123/291 (42%), Gaps = 57/291 (19%)
Query: 40 SEELIKSDQVNGVLVLSLLDKIIGAVDQIQLTQAQLEERQAEMEGAVQSIQGELSKLGKA 99
S EL+K + ++ K G ++Q+TQ LEE Q G + ++G+L + K
Sbjct: 152 SLELMKLRNKRETKMRGMMAKQEGMEMKLQVTQRSLEESQ----GKIAQLEGKLVSIEKE 207
Query: 100 HATTSNTVSKLLEKVRKVSVNVKTVRGSLERQAGQIKKLEVNEAELLRRRNFKVMIYQDE 159
+ KLLE + ++S +E+ I +LE N L+ +N DE
Sbjct: 208 KIDEKSETEKLLEYIEEIS----CASDQVEKYKLDIAQLEEN----LKEKN-------DE 252
Query: 160 VKLPAKLSISKSLKESEALPEKEGEELGEG----ERPEEDAAALELSSDEAVEVEE---- 211
+ LS+ +SL+E+ + K+ E+L E+ +ED +E + E
Sbjct: 253 I-----LSLKQSLEENIVILSKQVEDLNVKCQLLEKEKEDHVNRNREHNENLNAEMQNLK 307
Query: 212 ---VIEESRAERIKRSGL-----------------RRVDDFKKAFSKEK--MEKTKVRTR 249
++E+ E++++ L +++ F++ KEK E+ +T
Sbjct: 308 QKFILEQQEREKLQQKELQIDSLLQQEKELSSSLHQKLCSFQEEMVKEKNLFEEELKQTL 367
Query: 250 ENLEKTRLKTKENLEKTRHTLEKRMNKLGTRLVPAERREKLKTSRDKLRKS 300
+ L+K + K +E E+ LE+ L E EKLK +L KS
Sbjct: 368 DELDKLQQK-EEQAERLVKQLEEEAKSRAEELKLLE--EKLKGKEAELEKS 415
>gi|217416394 hyaluronan-mediated motility receptor isoform b [Homo
sapiens]
Length = 724
Score = 48.9 bits (115), Expect = 8e-06
Identities = 69/291 (23%), Positives = 123/291 (42%), Gaps = 57/291 (19%)
Query: 40 SEELIKSDQVNGVLVLSLLDKIIGAVDQIQLTQAQLEERQAEMEGAVQSIQGELSKLGKA 99
S EL+K + ++ K G ++Q+TQ LEE Q G + ++G+L + K
Sbjct: 167 SLELMKLRNKRETKMRGMMAKQEGMEMKLQVTQRSLEESQ----GKIAQLEGKLVSIEKE 222
Query: 100 HATTSNTVSKLLEKVRKVSVNVKTVRGSLERQAGQIKKLEVNEAELLRRRNFKVMIYQDE 159
+ KLLE + ++S +E+ I +LE N L+ +N DE
Sbjct: 223 KIDEKSETEKLLEYIEEIS----CASDQVEKYKLDIAQLEEN----LKEKN-------DE 267
Query: 160 VKLPAKLSISKSLKESEALPEKEGEELGEG----ERPEEDAAALELSSDEAVEVEE---- 211
+ LS+ +SL+E+ + K+ E+L E+ +ED +E + E
Sbjct: 268 I-----LSLKQSLEENIVILSKQVEDLNVKCQLLEKEKEDHVNRNREHNENLNAEMQNLK 322
Query: 212 ---VIEESRAERIKRSGL-----------------RRVDDFKKAFSKEK--MEKTKVRTR 249
++E+ E++++ L +++ F++ KEK E+ +T
Sbjct: 323 QKFILEQQEREKLQQKELQIDSLLQQEKELSSSLHQKLCSFQEEMVKEKNLFEEELKQTL 382
Query: 250 ENLEKTRLKTKENLEKTRHTLEKRMNKLGTRLVPAERREKLKTSRDKLRKS 300
+ L+K + K +E E+ LE+ L E EKLK +L KS
Sbjct: 383 DELDKLQQK-EEQAERLVKQLEEEAKSRAEELKLLE--EKLKGKEAELEKS 430
>gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin
(with transmembrane signal), 1 [Homo sapiens]
Length = 3259
Score = 48.9 bits (115), Expect = 8e-06
Identities = 67/286 (23%), Positives = 126/286 (44%), Gaps = 35/286 (12%)
Query: 14 PGYPDAEAPEPSSAGAQAAEEPSGAGSEELIKSDQVNGVLVLSLL---DKIIGAVDQI-Q 69
P P+ E+ P+ QA+ E SEE+ +D GV + S DK + AV I Q
Sbjct: 623 PLMPNEESSLPAVEKEQASTEHQSRTSEEISLNDA--GVELKSTKQDGDKSLSAVPDIGQ 680
Query: 70 LTQAQLEERQA---EMEGAVQSIQGELSKLGKAHATTSNTVSKLLEKVRKVSVNVKTVRG 126
Q +LE ++ E+E Q K A + +++L+E+ +K + N +
Sbjct: 681 CHQDELERLKSQILELELNFHKAQEIYEKNLDEKAKEISNLNQLIEEFKKNADNNSSAFT 740
Query: 127 SLERQA-----------------GQIKKLEVN--EAELLRRRNFKVMIYQDEVKLPAKLS 167
+L + Q+K+LE+N EAE RR +++ D + S
Sbjct: 741 ALSEERDQLLSQVKELSMVTELRAQVKQLEMNLAEAERQRRLDYESQTAHDNLLTEQIHS 800
Query: 168 ISKSLKESEALPEKEGEELGEGERPEEDAAALELSSDEAVEVEEVIEESRAERIKRSGLR 227
+S K + E EL + + + + L S ++ +E AER++
Sbjct: 801 LSIEAKSKDVKIEVLQNELDDVQLQFSEQSTLIRSLQSQLQNKESEVLEGAERVRHIS-S 859
Query: 228 RVDDFKKAFSKEKMEKTKVRTRENLEKTRLKTKENLEKTRHTLEKR 273
+V++ +A S++++E TK +++ L+ K ++E + T+E++
Sbjct: 860 KVEELSQALSQKELEITK------MDQLLLEKKRDVETLQQTIEEK 899
Score = 42.0 bits (97), Expect = 0.001
Identities = 61/298 (20%), Positives = 128/298 (42%), Gaps = 32/298 (10%)
Query: 26 SAGAQAAEEPSGAGSEELIKSDQVNGVLVLSLLDKIIGAVDQIQLTQAQLEERQAEMEGA 85
S +A+ + A S++ D++N L +DQ++ A LEE + + +
Sbjct: 1812 SESVPSAKSANPAVSKDFSSHDEINNYLQ---------QIDQLKERIAGLEEEKQKNKEF 1862
Query: 86 VQSIQGELSKLGKAHATTSNTVSKLLEKVRKVSVNVKTVRGSLERQAGQIKKLEVNEAEL 145
Q+++ E + L +T + L E+V K+++ + ++ L R ++K+ E +
Sbjct: 1863 SQTLENEKNTLLSQISTKDGELKMLQEEVTKMNLLNQQIQEELSR-VTKLKETAEEEKDD 1921
Query: 146 LRRRNFKVMIYQDEVKLPAKLSISKSLKESEALPEKEGEELGEGERPEEDAAALELSSDE 205
L R + A+L+ S + + EL E E EL ++
Sbjct: 1922 LEERLMNQL---------AELNGSIGNYCQDVTDAQIKNELLESEMKNLKKCVSELEEEK 1972
Query: 206 AVEVEE---VIEESRAERIKRSGLRRVDDFKKAFSKEKMEKTKVRTRE--NLEKTRLKTK 260
V+E V E R E +++ + + K+ +KE E K + +E L+K ++ +
Sbjct: 1973 QQLVKEKTKVESEIRKEYLEKIQGAQKEPGNKSHAKELQELLKEKQQEVKQLQKDCIRYQ 2032
Query: 261 ENLEKTRHTLEKRMNKLGTRLVPAERREKLKTSRDKLRKSFTPDHVVYARSKTAVYKV 318
E + T++ V E ++ L+ +++ L ++ +H A+++ A +KV
Sbjct: 2033 EKISALERTVK------ALEFVQTESQKDLEITKENLAQAV--EHRKKAQAELASFKV 2082
Score = 40.4 bits (93), Expect = 0.003
Identities = 64/279 (22%), Positives = 120/279 (43%), Gaps = 29/279 (10%)
Query: 30 QAAEEPSGAGSEELIKSDQVNGVLVLSLLDKIIGAVDQIQLTQAQLEERQAEMEGAVQSI 89
QA+ E + EE+ +Q ++SLL G + IQ+ A+L ++ + ++ +
Sbjct: 2364 QASRELTSRLHEEINMKEQK----IISLLS---GKEEAIQVAIAELRQQH---DKEIKEL 2413
Query: 90 QGELSKLGKAHATTSNTVSKLLEKVRKVSVNVKTVRGSLERQAGQIKKLEVNEAELLRRR 149
+ LS+ + + K ++K ++ +KT++ +Q Q+ + + L R
Sbjct: 2414 ENLLSQEEEENIVLEEENKKAVDKTNQLMETLKTIKKENIQQKAQLDSFVKSMSSLQNDR 2473
Query: 150 NFKVMIYQ--DEVKLPAKLSISKSLKESEALPEKEGEELGEGERPEEDAAALELSSDEAV 207
+ V YQ +E L L + ++E+ A K EE+ G R D +L+S+ A
Sbjct: 2474 DRIVGDYQQLEERHLSIILEKDQLIQEAAAENNKLKEEI-RGLRSHMD----DLNSENAK 2528
Query: 208 EVEEVIEESRAERIKRSGLRRVDDFKKAFSKEKMEKTKVRTRENLEKTRLKTKENL---E 264
E+I+ R L +V K + K+ +E +++ + LE K +E L E
Sbjct: 2529 LDAELIQ-------YREDLNQVITIKDSQQKQLLE-VQLQQNKELENKYAKLEEKLKESE 2580
Query: 265 KTRHTLEKRMNKLGTRLVPAERR-EKLKTSRDKLRKSFT 302
+ L + N L + E LK S +L + T
Sbjct: 2581 EANEDLRRSFNALQEEKQDLSKEIESLKVSISQLTRQVT 2619
Score = 40.0 bits (92), Expect = 0.004
Identities = 51/257 (19%), Positives = 112/257 (43%), Gaps = 26/257 (10%)
Query: 59 DKIIGAVDQIQLTQAQL---EERQAEMEGAVQSIQGELSKLGKAHATTSNTVSKLLEKV- 114
+ ++G + L Q +L E+R + +Q ++ E + L T LLEK+
Sbjct: 266 ESLVGRAQVVDLLQQELTAAEQRNQILSQQLQQMEAEHNTLRNTVETEREESKILLEKME 325
Query: 115 -----RKVSVNVKTVRGSLERQAGQIKKLEVNEAELLRRRNFKVMIYQDEVKLPAKLSIS 169
RK+S + ++ + Q ++ +AEL R + + + + ++ K S
Sbjct: 326 LEVAERKLSFH--NLQEEMHHLLEQFEQAGQAQAELESR--YSALEQKHKAEMEEKTSHI 381
Query: 170 KSLKESEALPEKEGEELGEG--ERPEEDAAALELSSDEAVEVEEVIEESRAERIKRSGLR 227
SL +K G+EL ++++ L+ +++AV+ + I++ + ++S +
Sbjct: 382 LSL-------QKTGQELQSACDALKDQNSKLLQDKNEQAVQSAQTIQQLEDQLQQKS--K 432
Query: 228 RVDDFKKAFSKEKMEKTKVRTRENL--EKTRLKTKENLEKTRHTLEKRMNKLGTRLVPAE 285
+ F ++ E + ++ E T+ T+EN+ + + + N+ G L+ +
Sbjct: 433 EISQFLNRLPLQQHETASQTSFPDVYNEGTQAVTEENIASLQKRVVELENEKGALLLSSI 492
Query: 286 RREKLKTSRDKLRKSFT 302
E+LK +KL T
Sbjct: 493 ELEELKAENEKLSSQIT 509
Score = 32.0 bits (71), Expect = 0.98
Identities = 78/376 (20%), Positives = 151/376 (40%), Gaps = 49/376 (13%)
Query: 40 SEELIK-SDQVN--GVLVLSLLDKIIGAVDQIQLTQAQLEERQAEMEGA--VQSIQGELS 94
SEE+ + +Q+N G+ + SL A + Q +LE Q ++ G ++ +Q +L
Sbjct: 1336 SEEVFQLQEQINKQGLEIESLKTVSHEAEVHAESLQQKLESSQLQIAGLEHLRELQPKLD 1395
Query: 95 KLGKAHATTSNTVSKLLEKVRKVSVNVKTVRGSLERQAGQIKKLEVNEAELLRRRNFKVM 154
+L K + VS L ++ + + ++ + Q IK L + + ++
Sbjct: 1396 ELQKLISKKEEDVSYLSGQLSEKEAALTKIQTEIIEQEDLIKALHTQLEMQAKEHDERIK 1455
Query: 155 IYQDEVKLPAKLSISKSLKESEALPEKEGEELGEGERPEEDAAALELSSDEAVEVEEVIE 214
Q E L E + PE+ GEE ++ + A +S EA++ + ++
Sbjct: 1456 QLQVE------------LCEMKQKPEEIGEESRAKQQIQRKLQAALISRKEALKENKSLQ 1503
Query: 215 ESRA------ERIKRSGLRRVDDFKKAFSKEK-----------MEKTKVRT---RENLEK 254
E + ER+ +S L V+ A +KEK E+ K+ T R LE
Sbjct: 1504 EELSLARGTIERLTKS-LADVESQVSAQNKEKDTVLGRLALLQEERDKLITEMDRSLLEN 1562
Query: 255 TRLKTK-ENLEKTRHTLEKRMNKLGTRLVPAERREKLKTSRD--KLRKSFTPDHVVYARS 311
L + E+L+ L + KL + + + + K+ S + + K ++ + +S
Sbjct: 1563 QSLSSSCESLKLALEGLTEDKEKL-VKEIESLKSSKIAESTEWQEKHKELQKEYEILLQS 1621
Query: 312 KTAVYKVPPFTFH-VKKIREGQVEVLKATEMVEVGADDDEGGAERGE------AGDLRRG 364
V H V+ +R+ + E+ E + E + E +R+
Sbjct: 1622 YENVSNEAERIQHVVEAVRQEKQELYGKLRSTEANKKETEKQLQEAEQEMEEMKEKMRKF 1681
Query: 365 SSPDVHALLEITEESD 380
+ +LE+ EE+D
Sbjct: 1682 AKSKQQKILELEEEND 1697
>gi|110624781 myosin, heavy polypeptide 13, skeletal muscle [Homo
sapiens]
Length = 1938
Score = 48.5 bits (114), Expect = 1e-05
Identities = 49/253 (19%), Positives = 120/253 (47%), Gaps = 24/253 (9%)
Query: 44 IKSDQVNGVLVLSLLDKIIGAVDQIQLTQAQLEERQAEMEGAVQSIQGELSKLGKAHATT 103
++ D+VNG++ ++ K+ D ++ + Q ++ +A++E A + ++G+L ++
Sbjct: 1016 VEEDKVNGLIKINA--KLEQQTDDLEGSLEQEKKLRADLERAKRKLEGDLKMSQESIMDL 1073
Query: 104 SNTVSKLLEKVRKVSVNVKTVRGSLERQAGQIKKLEVNEAELLRRRNFKVMIYQDEVKLP 163
N ++ EK++K + ++ ++ + + + EL R + E L
Sbjct: 1074 ENDKQQIEEKLKKKEFELSQLQAKIDDEQVHSLQFQKKIKELQARIEELEEEIEAEHTLR 1133
Query: 164 AKL-----SISKSLKE-SEALPEKEG---EELGEGERPEEDAAALELSSDEAVEVEE--- 211
AK+ +++ L+E SE L E G ++ ++ E + + +EA E
Sbjct: 1134 AKIEKQRSDLARELEEISERLEEASGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATA 1193
Query: 212 -VIEESRAERIKRSGLRRVDDFKKAFSKEKMEKTKVRTRENLE------KTRLKTKENLE 264
+ + +A+ + G ++D+ ++ K+K+EK K + ++ + K+K N+E
Sbjct: 1194 ATLRKKQADSVAELG-EQIDNLQRV--KQKLEKEKSELKMEIDDMASNIEALSKSKSNIE 1250
Query: 265 KTRHTLEKRMNKL 277
+T T+E + +++
Sbjct: 1251 RTCRTVEDQFSEI 1263
Score = 39.7 bits (91), Expect = 0.005
Identities = 53/272 (19%), Positives = 118/272 (43%), Gaps = 20/272 (7%)
Query: 41 EELIKSDQVNGVLVLSLLDKIIGAVD---QIQLTQAQLEERQAEMEGAVQSIQGELSKLG 97
E LIKS + V L +++ + ++ + LE++ + ++ + ++ L+K+
Sbjct: 910 EGLIKSKILLEAKVKELTERLEEEEEMNSELVAKKRNLEDKCSSLKRDIDDLELTLTKVE 969
Query: 98 KAHATTSNTVSKLLEKVRKVSVNV----KTVRGSLERQAGQIKKLEVNEAELLRRRNFKV 153
K T N V L E++ + N+ K + E + L+V E ++
Sbjct: 970 KEKHATENKVKNLSEEMTALEENISKLTKEKKSLQEAHQQTLDDLQVEEDKVNGLIKINA 1029
Query: 154 MIYQDEVKLPAKLSISKSLKESEALPEKEGEELGEGERPEEDAAALELSSDEAVEVEEVI 213
+ Q L L K L+ A E+ +L EG+ + ++L +D+ +++
Sbjct: 1030 KLEQQTDDLEGSLEQEKKLR---ADLERAKRKL-EGDLKMSQESIMDLENDK----QQIE 1081
Query: 214 EESRAERIKRSGLRRVDDFKKAFS---KEKMEKTKVRTRENLEKTRLK--TKENLEKTRH 268
E+ + + + S L+ D ++ S ++K+++ + R E E+ + + +EK R
Sbjct: 1082 EKLKKKEFELSQLQAKIDDEQVHSLQFQKKIKELQARIEELEEEIEAEHTLRAKIEKQRS 1141
Query: 269 TLEKRMNKLGTRLVPAERREKLKTSRDKLRKS 300
L + + ++ RL A + +K R++
Sbjct: 1142 DLARELEEISERLEEASGATSAQIEMNKKREA 1173
Score = 34.7 bits (78), Expect = 0.15
Identities = 60/296 (20%), Positives = 124/296 (41%), Gaps = 45/296 (15%)
Query: 55 LSLLDKIIGAVDQIQLTQAQLEERQAEMEGAVQSIQGELSKLGKAHATTSNTVSKLLEKV 114
L L K+ G ++++++ + AE + ++++QG+L K + H L+
Sbjct: 1616 LRLKKKMEGDLNEMEIQLGHSNRQMAETQKHLRTVQGQL-KDSQLH----------LDDA 1664
Query: 115 RKVSVNVKTVRGSLERQAGQIKKLEVNEAELLRRRNFKVMIYQDEVKLPAKLSISKSLKE 174
+ + ++K +ER+ G L + E E KV + Q E ++ L E
Sbjct: 1665 LRSNEDLKEQLAIVERRNG----LLLEELE-----EMKVALEQTER--------TRRLSE 1707
Query: 175 SEALPEKEGEELGEGERPEEDAAALELSSDEA---VEVEEVIEESRAERIKRSGLRRVDD 231
E L + +L + +L +D A EVE I+ESR K
Sbjct: 1708 QELLDASDRVQLLHSQNTSLINTKKKLEADIAQCQAEVENSIQESRNAEEKA-------- 1759
Query: 232 FKKAFSKEKMEKTKVRTRENLEKTRLKTKENLEKTRHTLEKRMNKLGTRLVPAERREKLK 291
KKA + M +++ ++ + K+NLE+T L+ R+++ +L +++++
Sbjct: 1760 -KKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDE-AEQLALKGGKKQIQ 1817
Query: 292 TSRDKLRKSFTPDHVVYARSKTAVYKVPPFTFHVKKI----REGQVEVLKATEMVE 343
+++R+ V R A+ + VK++ E +L+ ++V+
Sbjct: 1818 KLENRVRELENELDVEQKRGAEALKGAHKYERKVKEMTYQAEEDHKNILRLQDLVD 1873
>gi|115496169 myosin, heavy chain 7, cardiac muscle, beta [Homo
sapiens]
Length = 1935
Score = 47.8 bits (112), Expect = 2e-05
Identities = 61/282 (21%), Positives = 124/282 (43%), Gaps = 32/282 (11%)
Query: 45 KSDQVNGVLVLSLLDKIIGAVDQIQLTQAQLEERQAEMEGAVQSIQGELSKLGKAHATTS 104
+ D+VN + + K+ VD ++ + Q ++ + ++E A + ++G+L ++
Sbjct: 1013 EEDKVNTLTKAKV--KLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLE 1070
Query: 105 NTVSKLLEKVRKVSVNVKTVRGSLERQAGQIKKLEVNEAELLRRRNFKVMIYQDEVKLPA 164
N +L E+++K + + +E + +L+ EL R + E A
Sbjct: 1071 NDKQQLDERLKKKDFELNALNARIEDEQALGSQLQKKLKELQARIEELEEELEAERTARA 1130
Query: 165 KLS-----ISKSLKE-SEALPEKEGE---ELGEGERPEEDAAALELSSDEAVEVEEV--- 212
K+ +S+ L+E SE L E G ++ ++ E + + +EA E
Sbjct: 1131 KVEKLRSDLSRELEEISERLEEAGGATSVQIEMNKKREAEFQKMRRDLEEATLQHEATAA 1190
Query: 213 -IEESRAERIKRSGLRRVDDFKKAFSKEKMEKTKVRTRENLEKTR------LKTKENLEK 265
+ + A+ + G ++D+ ++ K+K+EK K + L+ +K K NLEK
Sbjct: 1191 ALRKKHADSVAELG-EQIDNLQRV--KQKLEKEKSEFKLELDDVTSNMEQIIKAKANLEK 1247
Query: 266 TRHTLEKRMNKLGTRLVPAER--------REKLKTSRDKLRK 299
TLE +MN+ ++ +R R KL+T +L +
Sbjct: 1248 MCRTLEDQMNEHRSKAEETQRSVNDLTSQRAKLQTENGELSR 1289
Score = 42.0 bits (97), Expect = 0.001
Identities = 58/258 (22%), Positives = 105/258 (40%), Gaps = 26/258 (10%)
Query: 23 EPSSAGAQAAEEPSGAGSEELIKSDQVNGVLVLSLLDKIIGAVDQIQLTQAQLEERQAEM 82
E A + E +ELI++ + V L + ++Q + A L + Q E+
Sbjct: 1686 EELRAVVEQTERSRKLAEQELIETSE----RVQLLHSQNTSLINQKKKMDADLSQLQTEV 1741
Query: 83 EGAVQSIQGELSKLGKAHATTSNTVSKLLEKVRKVSVNVKTVRGSLERQAGQIKKLEVNE 142
E AVQ + K KA T + +++ L+K + S +++ ++ ++E+ ++ ++E
Sbjct: 1742 EEAVQECRNAEEKAKKA-ITDAAMMAEELKKEQDTSAHLERMKKNMEQTIKDLQH-RLDE 1799
Query: 143 AELLRRRNFKVMIYQDEVKLPAKLSISKSLKESEA-LPEKEGEELGEGERPEEDAAALEL 201
AE + + K K L++ EA + E E E E +R E +
Sbjct: 1800 AEQIALKGGK-----------------KQLQKLEARVRELENELEAEQKRNAESVKGMRK 1842
Query: 202 SSDEAVEVEEVIEESRAERIKRSGLRRVDDFKKAFSKEKMEKTKVRTRENLEKTRLKTKE 261
S E+ EE R ++ L K K + E+ + + NL K R E
Sbjct: 1843 SERRIKELTYQTEEDRKNLLRLQDLVDKLQLKVKAYKRQAEEAEEQANTNLSKFRKVQHE 1902
Query: 262 --NLEKTRHTLEKRMNKL 277
E+ E ++NKL
Sbjct: 1903 LDEAEERADIAESQVNKL 1920
Score = 37.0 bits (84), Expect = 0.031
Identities = 44/245 (17%), Positives = 109/245 (44%), Gaps = 21/245 (8%)
Query: 67 QIQLTQAQLEERQAEMEGAVQSIQGELSKLGKAHATTSNTVSKLLEKVRKVSVNVKTVRG 126
++ + +LE+ +E++ + ++ L+K+ K T N V L E++ + +
Sbjct: 935 ELTAKKRKLEDECSELKRDIDDLELTLAKVEKEKHATENKVKNLTEEM----AGLDEIIA 990
Query: 127 SLERQAGQIKKLEVNEAELLRRRNFKVMIYQDEVKLPAKLSISKSLKESEALPEKEGEEL 186
L ++ +++ + L+ KV AK+ + + + + E E+E +
Sbjct: 991 KLTKEKKALQEAHQQALDDLQAEEDKV-----NTLTKAKVKLEQQVDDLEGSLEQEKKVR 1045
Query: 187 GEGERPEEDAAA-LELSSDEAVEVEEVIEESRAERIKRSGLR------RVDDFKKAFS-- 237
+ ER + L+L+ + +++E ++ ER+K+ R++D + S
Sbjct: 1046 MDLERAKRKLEGDLKLTQESIMDLEN-DKQQLDERLKKKDFELNALNARIEDEQALGSQL 1104
Query: 238 KEKMEKTKVRTRENLEKTRLK--TKENLEKTRHTLEKRMNKLGTRLVPAERREKLKTSRD 295
++K+++ + R E E+ + + +EK R L + + ++ RL A ++ +
Sbjct: 1105 QKKLKELQARIEELEEELEAERTARAKVEKLRSDLSRELEEISERLEEAGGATSVQIEMN 1164
Query: 296 KLRKS 300
K R++
Sbjct: 1165 KKREA 1169
>gi|153791497 ciliary rootlet coiled-coil [Homo sapiens]
Length = 2017
Score = 47.8 bits (112), Expect = 2e-05
Identities = 62/268 (23%), Positives = 112/268 (41%), Gaps = 9/268 (3%)
Query: 32 AEEPSGAGSEELIKSDQVNGVLVLSLLDKIIGAVDQIQLTQAQLEERQAEMEGAVQSIQG 91
A E S+E I + N + ++ +D + +LE ++ +EG +Q +
Sbjct: 1611 ATESELRASQEKISKMKANETKLEGDKRRLKEVLDASESRTVKLELQRRSLEGELQRSRL 1670
Query: 92 ELSKLGKAHATTSNTVSKLLEKVRKVSVNVKTVRGSLERQAGQIKKLEVNEAELLRR-RN 150
LS + V L +V V T++ ++ER G + K+E +E L + R
Sbjct: 1671 GLSDREAQAQALQDRVDSLQRQVADSEVKAGTLQLTVERLNGALAKVEESEGALRDKVRG 1730
Query: 151 FKVMIYQDEVKLPAKLSISKSLKESEALPEKEGEELGEGERPEEDAAALELSSDEAVEVE 210
+ Q L + + K+L +AL E + ER + AL + ++ +
Sbjct: 1731 LTEALAQSSASLNS--TRDKNLHLQKALTACEHDRQVLQERLDAARQALSEARKQSSSLG 1788
Query: 211 EVIEESRAERIKRSGLRRVDDFKKAFSKEKMEKTKVRTRENLEKTRLKTKENLEKTRHTL 270
E ++ R E + L+RV+ A + + + +R R+ E L T + L+ R L
Sbjct: 1789 EQVQTLRGE-VADLELQRVE----AEGQLQQLREVLRQRQEGEAAALNTVQKLQDERRLL 1843
Query: 271 EKRMNKLGTRLVPAERREKLKTSRDKLR 298
++R+ L L E EK + R LR
Sbjct: 1844 QERLGSLQRALAQLE-AEKREVERSALR 1870
Score = 46.2 bits (108), Expect = 5e-05
Identities = 50/218 (22%), Positives = 96/218 (44%), Gaps = 20/218 (9%)
Query: 72 QAQLEERQAEMEGAVQSIQGELSKLGKAHATTSNTVSKLLEKVRKVSVNVKTVRGSLERQ 131
+AQ EE A V+ +Q + LGK + +L ++R + + R L R
Sbjct: 1121 RAQREEAAAAHAQEVRRLQEQARDLGKQRDSCLREAEELRTQLRLL----EDARDGLRR- 1175
Query: 132 AGQIKKLEVNEAELLRRRNFKVMIYQDEVKLPAKLSISKSLKESEALPEKEGEELGEGER 191
E+ EA+ R + + Q + + S+ + KE EAL E ++
Sbjct: 1176 -------ELLEAQRKLRESQEGREVQRQEAGELRRSLGEGAKEREALRRSNEELRSAVKK 1228
Query: 192 PEEDAAALELSSDEAVEVEEVIEESRAERIKRSGLRRVDDFKKAFSKEKMEKTKVRTREN 251
E + +L+L++++ + ++EE+R K +G R +++E++++ R
Sbjct: 1229 AESERISLKLANEDKEQKLALLEEARTAVGKEAGELRT-------GLQEVERSRLEARRE 1281
Query: 252 LEKTRLKTKENLEKTRHTLEKRMNKLGTRLVPAERREK 289
L++ R + K L+ L + + +L RL ER EK
Sbjct: 1282 LQELRRQMK-MLDSENTRLGRELAELQGRLALGERAEK 1318
Score = 33.9 bits (76), Expect = 0.26
Identities = 72/330 (21%), Positives = 124/330 (37%), Gaps = 43/330 (13%)
Query: 11 RPLPGYPDAEAP---------EPSSAGAQAAEEPSGAGSEELIKSDQVNGVLVLSLLDKI 61
RP+PG P +AP PS+ +P G S ++ V L +
Sbjct: 1455 RPVPGSPARDAPAEGSGEGLNSPSTLECSPGSQPPSPGPATSPASPDLDPEAVRGALREF 1514
Query: 62 IGAV-------DQIQLTQAQLEERQAEMEGAVQSIQGELSKLGKAHATT----------- 103
+ + D+++ + L + AEME S +L KA A +
Sbjct: 1515 LQELRSAQRERDELRTQTSALNRQLAEMEAERDSATSRARQLQKAVAESEEARRSVDGRL 1574
Query: 104 SNTVSKLLEKVRKVSVNVKTVRGSLERQAGQIKKLEVNEAELLRRRNFKVMIYQDEVKLP 163
S ++L + V + + R +L++ A + L+ E+EL + + +E KL
Sbjct: 1575 SGVQAELALQEESVRRSERERRATLDQVATLERSLQATESELRASQEKISKMKANETKLE 1634
Query: 164 A-KLSISKSLKESEALPEK--------EGE----ELGEGERPEEDAAALELSSDEAVEVE 210
K + + L SE+ K EGE LG +R E A AL+ D +++ +
Sbjct: 1635 GDKRRLKEVLDASESRTVKLELQRRSLEGELQRSRLGLSDR-EAQAQALQDRVD-SLQRQ 1692
Query: 211 EVIEESRAERIKRSGLRRVDDFKKAFSKEKMEKTKVR-TRENLEKTRLKTKENLEKTRHT 269
E +A ++ + R K E + KVR E L ++ +K H
Sbjct: 1693 VADSEVKAGTLQLTVERLNGALAKVEESEGALRDKVRGLTEALAQSSASLNSTRDKNLHL 1752
Query: 270 LEKRMNKLGTRLVPAERREKLKTSRDKLRK 299
+ R V ER + + + + RK
Sbjct: 1753 QKALTACEHDRQVLQERLDAARQALSEARK 1782
>gi|110611903 myosin, heavy polypeptide 4, skeletal muscle [Homo
sapiens]
Length = 1939
Score = 47.8 bits (112), Expect = 2e-05
Identities = 57/256 (22%), Positives = 113/256 (44%), Gaps = 24/256 (9%)
Query: 44 IKSDQVNGVLVLSLLDKIIGAVDQIQLTQAQLEERQAEMEGAVQSIQGELSKLGKAHATT 103
++ D+VN + K+ VD ++ + Q ++ ++E A + ++G+L ++ T
Sbjct: 1016 MEEDKVN--TLTKAKTKLEQQVDDLEGSLEQEKKLCMDLERAKRKLEGDLKLAQESTMDT 1073
Query: 104 SNTVSKLLEKVRKVSVNVKTVRGSLERQAGQIKKLEVNEAELLRRRNFKVMIYQDEVKLP 163
N +L EK++K + ++G +E + +L+ EL R + E
Sbjct: 1074 ENDKQQLNEKLKKKEFEMSNLQGKIEDEQALAIQLQKKIKELQARIEELEEEIEAERASR 1133
Query: 164 AKL-----SISKSLKE-SEALPEKEGEELGEGERPEEDAAA-------LELSSDEAVEVE 210
AK +S+ L+E SE L E G + E ++ A LE S+ +
Sbjct: 1134 AKAEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEESTLQHEATA 1193
Query: 211 EVIEESRAERIKRSGLRRVDDFKKAFSKEKMEKTKVRTRENLE------KTRLKTKENLE 264
+ + A+ + G ++D ++ K+K+EK K + + +T K K N E
Sbjct: 1194 AALRKKHADSVAELG-EQIDSLQRV--KQKLEKEKSELKMEINDLASNMETVSKAKANFE 1250
Query: 265 KTRHTLEKRMNKLGTR 280
K TLE +++++ T+
Sbjct: 1251 KMCRTLEDQLSEIKTK 1266
Score = 35.8 bits (81), Expect = 0.068
Identities = 49/247 (19%), Positives = 97/247 (39%), Gaps = 42/247 (17%)
Query: 67 QIQLTQAQLEERQAEMEGAVQSIQGELSKLGKAHATTSNTVSKLLEKVRKVSVNV----K 122
++ + +LE+ +E++ + ++ L+K+ K T N V L E++ + + K
Sbjct: 939 ELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTK 998
Query: 123 TVRGSLERQAGQIKKLEVNEAELLRRRNFKVMIYQDEVKLPAKLSISKSL---------- 172
+ E + L++ E ++ K + Q L L K L
Sbjct: 999 EKKALQEAHQQTLDDLQMEEDKVNTLTKAKTKLEQQVDDLEGSLEQEKKLCMDLERAKRK 1058
Query: 173 --------KESEALPEKEGEELGE-------------GERPEEDAAALELS---SDEAVE 208
+ES E + ++L E G+ +E A A++L +
Sbjct: 1059 LEGDLKLAQESTMDTENDKQQLNEKLKKKEFEMSNLQGKIEDEQALAIQLQKKIKELQAR 1118
Query: 209 VEEVIEESRAERIKRS-GLRRVDDFKKAFSK--EKMEKTKVRTRENLEKTRLKTKENLEK 265
+EE+ EE AER R+ ++ D + + E++E+ T +E + K + +K
Sbjct: 1119 IEELEEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQIEMNK-KREAEFQK 1177
Query: 266 TRHTLEK 272
R LE+
Sbjct: 1178 MRRDLEE 1184
Score = 29.3 bits (64), Expect = 6.4
Identities = 52/300 (17%), Positives = 125/300 (41%), Gaps = 52/300 (17%)
Query: 87 QSIQGELSKLGKAHATTSNTVSKLLEKVRK--------VSVNVKTVRGSLERQAGQIKKL 138
+++Q E+S L + A + +L EKV+K + +++ SLE + G+I ++
Sbjct: 1507 KNLQQEISDLTEQIAEGGKHIHEL-EKVKKQLDHEKSELQTSLEEAEASLEHEEGKILRI 1565
Query: 139 EV-----------------NEAELLRRRNFKVM----------IYQDEVKLPAKLSISKS 171
++ E + L+R + +V+ I L K +
Sbjct: 1566 QLELNQVKSEIDRKIAEKDEELDQLKRNHLRVVESMQSTLDAEIRSRNDALRIKKKMEGD 1625
Query: 172 LKESEALPEKEGEELGEGERPEEDAAAL----ELSSDEAVEVEEVIEESRAERIKRSGLR 227
L E E + E R + + +L D+A+ ++ ++E A +R+ L
Sbjct: 1626 LNEMEIQLNHANRQAAEALRNLRNTQGILKDTQLHLDDAIRGQDDLKEQLAMVERRANLM 1685
Query: 228 RVDDFKKAFSKEKMEKTKVRTRENL----EKTRLKTKEN--LEKTRHTLEKRMNKLGTRL 281
+ + + S E+ E+ + + L E+ +L +N L T+ LE ++++ +
Sbjct: 1686 QAEVEELRASLERTERGRKMAEQELLDASERVQLLHTQNTSLINTKKKLETDISQIQGEM 1745
Query: 282 VPAERREKLKTSRDKLRKSFTPDHVVYARSKTAVYKVPPFTFHVKKIREGQVEVLKATEM 341
+ ++ + + +K +K+ T ++ K K + H++++++ + +K ++
Sbjct: 1746 --EDIVQEARNAEEKAKKAITDAAMMAEELK----KEQDTSAHLERMKKNMEQTVKDLQL 1799
>gi|115298682 HBxAg transactivated protein 2 [Homo sapiens]
Length = 2817
Score = 47.0 bits (110), Expect = 3e-05
Identities = 54/212 (25%), Positives = 96/212 (45%), Gaps = 15/212 (7%)
Query: 95 KLGKAHATTSNTVSKLLEKVRKVSVNVKTVRGSLERQAGQIKKLEVNEAELLRRRNFKVM 154
++ K + +S +E+ RK R ER+ + +K AE L+R + K+
Sbjct: 443 EIWKQRRRQQSEISAAVERARKR-------REEEERRMEEQRKAAC--AEKLKRLDEKLG 493
Query: 155 IYQDEVKLPAKLSISKSLKESEALPEKEGEELGEGERPEEDAAALELSSDEAVEVEEVIE 214
I + K P+ I + +E E EKE E+ E ER +E E ++ E+E+ E
Sbjct: 494 ILE---KQPSPEEIREREREKEREREKELEKEQEQEREKEREKDRERQQEKEKELEKEQE 550
Query: 215 ESRAERIKRSGLRRVDDFKKAFSKEKMEKTKVRTRE-NLEKTRLKTKENLEKTRHTLEKR 273
+ R +R + + ++ +++++K K + +E LEK R K +E +E LE
Sbjct: 551 KQREMEKERKQEKEKELERQKEKEKELQKMKEQEKECELEKEREKLEEKIEPREPNLEPM 610
Query: 274 MNKLGTRLVPAERREKLKTSRDKLR--KSFTP 303
+ K + + E + T +D R K TP
Sbjct: 611 VEKQESENSCNKEEEPVFTRQDSNRSEKEATP 642
>gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens]
Length = 1976
Score = 46.2 bits (108), Expect = 5e-05
Identities = 58/287 (20%), Positives = 129/287 (44%), Gaps = 14/287 (4%)
Query: 18 DAEAPEPSSAGAQAAEEPSGAGSEELIKSDQVNGVLVLSLLDKIIGAVDQIQLTQAQLEE 77
+AE A A+ E ++EL++ + + + S + ++ + +Q Q + EE
Sbjct: 1298 EAEKKGIKFAKDAASLESQLQDTQELLQEETRQKLNLSSRIRQLEEEKNSLQEQQEEEEE 1357
Query: 78 RQAEMEGAVQSIQGELSKLGKAHATTSNTVSKLLEKVRKVSVNVKTVRGSLERQAGQIKK 137
+ +E V ++Q +L+ K T+ L E +K+ + + + LE +A K
Sbjct: 1358 ARKNLEKQVLALQSQLADTKKKVDDDLGTIESLEEAKKKLLKDAEALSQRLEEKALAYDK 1417
Query: 138 LEVNEAELLRRRNFKVMIYQDEVKLPAKL-----SISKSLKESEALPEKEGEE--LGEGE 190
LE + L + + + + ++ + L + L E +++ + EE E E
Sbjct: 1418 LEKTKNRLQQELDDLTVDLDHQRQVASNLEKKQKKFDQLLAEEKSISARYAEERDRAEAE 1477
Query: 191 RPEEDAAALELSS--DEAVEVEEVIEESRAERIKRSGLRRVDDFKKAFSK--EKMEKTKV 246
E++ AL L+ +EA+E +E E R + R+ + + K K ++EK+K
Sbjct: 1478 AREKETKALSLARALEEALEAKEEFE--RQNKQLRADMEDLMSSKDDVGKNVHELEKSKR 1535
Query: 247 RTRENLEKTRLKTKENLEKTRHTLEKRMN-KLGTRLVPAERREKLKT 292
+ +E+ R + +E ++ + T + ++ ++ + + A+ L+T
Sbjct: 1536 ALEQQVEEMRTQLEELEDELQATEDAKLRLEVNMQAMKAQFERDLQT 1582
Score = 40.8 bits (94), Expect = 0.002
Identities = 76/358 (21%), Positives = 146/358 (40%), Gaps = 52/358 (14%)
Query: 58 LDKIIGAVDQIQLTQAQLEERQAEMEGAVQSIQGELSKLGKAHATTSNTV----SKLLEK 113
LD+ GA ++QL + E + +ME + ++ + SK K + + S+L E+
Sbjct: 959 LDEEEGARQKLQLEKVTAEAKIKKMEEEILLLEDQNSKFIKEKKLMEDRIAECSSQLAEE 1018
Query: 114 VRKVSVNVKTVRGSLERQAG----QIKKLEVNEAEL---LRRRNFKVMIYQDEV-KLPAK 165
K N+ +R E ++KK E EL R+ + + QD++ +L A+
Sbjct: 1019 EEKAK-NLAKIRNKQEVMISDLEERLKKEEKTRQELEKAKRKLDGETTDLQDQIAELQAQ 1077
Query: 166 LSISKSLKESEALPEKEGEELGEGERPEEDAA----ALELSSDEAVEVEEVIEESRAERI 221
+ K L +KE E G R +++ AL++ + ++ E+ E+ +E+
Sbjct: 1078 IDELKL-----QLAKKEEELQGALARGDDETLHKNNALKVVRELQAQIAELQEDFESEKA 1132
Query: 222 KRSGLRRVDDFKKAFSKEKMEKTKVRTRENLEKT----RLKTKEN---------LEKTRH 268
R+ + +K E++E K + L+ T L+TK LE+
Sbjct: 1133 SRNKAEK----QKRDLSEELEALKTELEDTLDTTAAQQELRTKREQEVAELKKALEEETK 1188
Query: 269 TLEKRMNKLGTRLVPA--------ERREKLKTSRDKLRKSFTPDHVVYARSKTAVYKVPP 320
E ++ + R A E+ ++ K + +K ++ D+ A + +V
Sbjct: 1189 NHEAQIQDMRQRHATALEELSEQLEQAKRFKANLEKNKQGLETDNKELACEVKVLQQVKA 1248
Query: 321 FTFHVKKIREGQVEVLKATEMVEVGADDDEGGAERGEAGDLRRGSSPDVHALLEITEE 378
+ H +K + QV+ L A ++ D E E + +V LLE E+
Sbjct: 1249 ESEHKRKKLDAQVQELHAKV-----SEGDRLRVELAEKASKLQNELDNVSTLLEEAEK 1301
Score = 35.0 bits (79), Expect = 0.12
Identities = 51/258 (19%), Positives = 103/258 (39%), Gaps = 17/258 (6%)
Query: 41 EELIKSDQVNGVLVLSLLDKIIGAVDQIQLTQAQLEERQAEMEGAVQSIQGELSKLGKAH 100
+EL K+ + L D+I QI + QL +++ E++GA+ +G+ L K +
Sbjct: 1051 QELEKAKRKLDGETTDLQDQIAELQAQIDELKLQLAKKEEELQGAL--ARGDDETLHKNN 1108
Query: 101 ATTSNTVSKLLEKVRKVSVNVKTVRGSLERQAGQIKKLEVNEAELLRRRNFKVMIYQDEV 160
A L+ VR++ + ++ E + K E + +L +D +
Sbjct: 1109 A---------LKVVRELQAQIAELQEDFESEKASRNKAEKQKRDLSEELEALKTELEDTL 1159
Query: 161 KLPAKLSISKSLKESEALPEKEGEELGEGERPEEDAAALELSSDEAVEVEEVIEESRAER 220
A ++ +E E K+ E E +A ++ A +EE+ E+ +
Sbjct: 1160 DTTAAQQELRTKREQEVAELKKAL---EEETKNHEAQIQDMRQRHATALEELSEQLEQAK 1216
Query: 221 IKRSGLRRVDDFKKAFSKEKMEKTKVRTRENLEKTRLKTKENLE-KTRHTLEKRMNKLGT 279
++ L + + +KE + KV + E + K + + + H ++L
Sbjct: 1217 RFKANLEKNKQGLETDNKELACEVKVLQQVKAESEHKRKKLDAQVQELHAKVSEGDRLRV 1276
Query: 280 RLVPAERREKLKTSRDKL 297
L AE+ KL+ D +
Sbjct: 1277 EL--AEKASKLQNELDNV 1292
Score = 32.7 bits (73), Expect = 0.58
Identities = 55/238 (23%), Positives = 106/238 (44%), Gaps = 43/238 (18%)
Query: 65 VDQIQLTQAQLEERQAEMEGAVQSIQGELSKLGKAHATTSNTVSKLLEKVRKVSVNVKTV 124
+ Q++ QAQ+++ Q E+E +A A+ ++ E +K+
Sbjct: 1644 IKQLRKLQAQMKDYQRELE--------------EARASRDEIFAQSKESEKKLK------ 1683
Query: 125 RGSLERQAGQIKKLEVNEAELLRRRNFKVMIYQDEVKLPAKLSISKSLKESEALPEK--- 181
SLE + Q+++ E+ +E RR Q+ +L +++ S S K S L EK
Sbjct: 1684 --SLEAEILQLQE-ELASSERARRH-----AEQERDELADEITNSASGK-SALLDEKRRL 1734
Query: 182 EGEELGEGERPEEDAAALELSSDEAVEVEEVIEESRAE-RIKRSGLRRVDDFKKAFSKEK 240
E E EE+ + +EL +D + ++ AE +RS ++ D+ ++ ++
Sbjct: 1735 EARIAQLEEELEEEQSNMELLNDRFRKTTLQVDTLNAELAAERSAAQKSDNARQQLERQN 1794
Query: 241 ME-KTKVRTRENLEKTRLKTKENLEKTRHTLEKRMNKLGTRLVPAERREKLKTSRDKL 297
E K K++ E K++ K T LE ++ +L +L E+ K + + +KL
Sbjct: 1795 KELKAKLQELEGAVKSKFKA------TISALEAKIGQLEEQL---EQEAKERAAANKL 1843
Score = 30.0 bits (66), Expect = 3.7
Identities = 25/122 (20%), Positives = 54/122 (44%), Gaps = 17/122 (13%)
Query: 44 IKSDQVNGVLVL--SLLDKIIGAVDQIQLTQAQLEERQAEMEGAVQS------------- 88
++ D +N L S K A Q++ +L+ + E+EGAV+S
Sbjct: 1764 LQVDTLNAELAAERSAAQKSDNARQQLERQNKELKAKLQELEGAVKSKFKATISALEAKI 1823
Query: 89 --IQGELSKLGKAHATTSNTVSKLLEKVRKVSVNVKTVRGSLERQAGQIKKLEVNEAELL 146
++ +L + K A + V + +K++++ + V+ R ++ Q++K +L
Sbjct: 1824 GQLEEQLEQEAKERAAANKLVRRTEKKLKEIFMQVEDERRHADQYKEQMEKANARMKQLK 1883
Query: 147 RR 148
R+
Sbjct: 1884 RQ 1885
>gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens]
Length = 1960
Score = 45.8 bits (107), Expect = 7e-05
Identities = 70/334 (20%), Positives = 140/334 (41%), Gaps = 34/334 (10%)
Query: 75 LEERQAEMEGAVQSIQGELSKLGKAHATTSNTVSKLLEKVRKVSVNVKTVRGSLERQAGQ 134
L + + + E + ++ +L +L ++L +KV K+ V + V G L + +
Sbjct: 1236 LLQGKGDSEHKRKKVEAQLQELQVKFNEGERVRTELADKVTKLQVELDNVTGLLSQSDSK 1295
Query: 135 IKKLEVNEAELLRRRNFKVMIYQDEVKLPAKLSISKSLKESEALPEKEGEELGEGERP-- 192
KL + + L + + Q+E + KLS+S LK+ E E+L E E
Sbjct: 1296 SSKLTKDFSALESQLQDTQELLQEENR--QKLSLSTKLKQVEDEKNSFREQLEEEEEAKH 1353
Query: 193 --EEDAAALELSSDEAVEVEEVIEES-----RAERIKRSGLRRVDDF-----KKAFSKEK 240
E+ A L + ++++ +E+S AE +KR + ++ +K + +K
Sbjct: 1354 NLEKQIATLHA---QVADMKKKMEDSVGCLETAEEVKRKLQKDLEGLSQRHEEKVAAYDK 1410
Query: 241 MEKTKVRTRENLEKTRLKTKENLEKTRHTLEKRMNKLGTRLVPAERREKLKTSRDKLRKS 300
+EKTK R ++ L+ L ++ ++ LEK+ K +L+ E+ K + ++ R
Sbjct: 1411 LEKTKTRLQQELDDL-LVDLDHQRQSACNLEKKQKKF-DQLLAEEKTISAKYAEERDRAE 1468
Query: 301 FTPDHVVYARSKTAVYKVPPFTFHVKKIREGQVEVLK-----ATEMVEVGADDDEGGAER 355
A ++ K +++ E + E+ + TEM ++ + D+ G
Sbjct: 1469 --------AEAREKETKALSLARALEEAMEQKAELERLNKQFRTEMEDLMSSKDDVGKSV 1520
Query: 356 GEAGDLRRGSSPDVHALLEITEESDAVLVDKSDS 389
E +R V + EE + L D+
Sbjct: 1521 HELEKSKRALEQQVEEMKTQLEELEDELQATEDA 1554
Score = 45.4 bits (106), Expect = 9e-05
Identities = 65/280 (23%), Positives = 123/280 (43%), Gaps = 30/280 (10%)
Query: 23 EPSSAGAQAAEEPSGAGSEELIKSDQVNGVLVLSLLDKIIGAVDQIQLTQAQLEERQAEM 82
E + A+ AEE A +E K + LSL + A++Q +A+LE +
Sbjct: 1452 EEKTISAKYAEERDRAEAEAREKETKA-----LSLARALEEAMEQ----KAELERLNKQF 1502
Query: 83 EGAVQSIQGELSKLGKAHATTSNTVSKLLEKVRKVSVNVKTVRGSLERQAGQIKKLEVNE 142
++ + +GK+ + L ++V ++ ++ + L+ +LEVN
Sbjct: 1503 RTEMEDLMSSKDDVGKSVHELEKSKRALEQQVEEMKTQLEELEDELQATEDAKLRLEVN- 1561
Query: 143 AELLRRRNFKVMIYQDEVKLPAKLSISKSLKESEALPEKEGEE----LGEGERPEEDAAA 198
+ ++ + + + +DE K + + ++E EA E E ++ + ++ E D
Sbjct: 1562 LQAMKAQFERDLQGRDEQSEEKKKQLVRQVREMEAELEDERKQRSMAVAARKKLEMDLKD 1621
Query: 199 LELSSDEAVEVEEVIEESRAERIKRSGLRRVDDFKKAFSKEKMEKTKVRTRENLEKTRLK 258
LE D A ++R E IK+ LR++ K +E + TR + E+ +
Sbjct: 1622 LEAHIDSA-------NKNRDEAIKQ--LRKLQAQMKDCMRELDD-----TRASREEILAQ 1667
Query: 259 TKENLEKTRHTLEKRMNKLGTRLVPAER-REKLKTSRDKL 297
KEN EK ++E M +L L AER + + + RD+L
Sbjct: 1668 AKEN-EKKLKSMEAEMIQLQEELAAAERAKRQAQQERDEL 1706
Score = 43.9 bits (102), Expect = 2e-04
Identities = 48/254 (18%), Positives = 115/254 (45%), Gaps = 53/254 (20%)
Query: 66 DQIQLTQAQLEERQAE----------MEGAVQSIQGELSKLGKAHATTSNTVSKLLEKVR 115
D + T AQ E R +E ++ + ++ ++ + H+ +++ LE+ +
Sbjct: 1150 DTLDSTAAQQELRSKREQEVNILKKTLEEEAKTHEAQIQEMRQKHSQAVEELAEQLEQTK 1209
Query: 116 KVSVNVKTVRGSLERQAGQIKKLEVNEAELL---------RRRNFKVMIYQDEVKLPAKL 166
+V N++ + +LE + G++ NE ++L +R+ + + + +VK
Sbjct: 1210 RVKANLEKAKQTLENERGEL----ANEVKVLLQGKGDSEHKRKKVEAQLQELQVKFNEGE 1265
Query: 167 SISKSLKESEALPEKEGEELGEGERPEEDAAALELSSD------EAVEVEEVIEESRAER 220
+ L + + E + + G + D+ + +L+ D + + +E+++E ++
Sbjct: 1266 RVRTELADKVTKLQVELDNV-TGLLSQSDSKSSKLTKDFSALESQLQDTQELLQEENRQK 1324
Query: 221 IKRSG-LRRVDDFKKAFSKEKMEKTKVRTRENLEKTRLKTKENLEKTRHTLEKRMNKLGT 279
+ S L++V+D K +F RE LE+ E+ +H LEK++ L
Sbjct: 1325 LSLSTKLKQVEDEKNSF------------REQLEEE--------EEAKHNLEKQIATLHA 1364
Query: 280 RLVPAERREKLKTS 293
++ A+ ++K++ S
Sbjct: 1365 QV--ADMKKKMEDS 1376
Score = 38.9 bits (89), Expect = 0.008
Identities = 48/211 (22%), Positives = 96/211 (45%), Gaps = 22/211 (10%)
Query: 76 EERQAEMEGAVQSIQGELSKLGKAHATTSNTVSKLLEKVRKVSVNVKTVRGSLERQAGQI 135
E+++ E+E + ++G+ + L A +++L ++ K ++ +E +A Q
Sbjct: 1040 EKQRQELEKTRRKLEGDSTDLSDQIAELQAQIAELKMQLAKKEEELQAALARVEEEAAQ- 1098
Query: 136 KKLEVNEAELLRRRNFKVMIYQDEVKLPAKLSISKSLKESEALPEKEGEELGEGERPEED 195
K + + + +R ++ Q++++ + S +K+ K+ L GEEL + ED
Sbjct: 1099 KNMALKK---IRELESQISELQEDLE-SERASRNKAEKQKRDL----GEELEALKTELED 1150
Query: 196 -----AAALELSSDEAVEVEEVIEESRAERIKRSGLRRVDDFKKAFSKEKMEKTKVRTRE 250
AA EL S EV I + E ++ ++ + ++ S+ E E
Sbjct: 1151 TLDSTAAQQELRSKREQEVN--ILKKTLEEEAKTHEAQIQEMRQKHSQAVEELA-----E 1203
Query: 251 NLEKTRLKTKENLEKTRHTLEKRMNKLGTRL 281
LE+T+ + K NLEK + TLE +L +
Sbjct: 1204 QLEQTK-RVKANLEKAKQTLENERGELANEV 1233
Score = 36.2 bits (82), Expect = 0.052
Identities = 51/254 (20%), Positives = 107/254 (42%), Gaps = 31/254 (12%)
Query: 55 LSLLDKIIGAVDQIQLTQAQLEERQA---EMEGAVQSIQGELSKLGKAHATTSNTVSKLL 111
LSL K+ D+ + QLEE + +E + ++ +++ + K + +
Sbjct: 1325 LSLSTKLKQVEDEKNSFREQLEEEEEAKHNLEKQIATLHAQVADMKKKMEDSVGCLETAE 1384
Query: 112 EKVRKVSVNVKTVRGSLERQAGQIKKLEVNEAELLRRRNFKVMIYQDEVKLPA------K 165
E RK+ +++ + E + KLE + L + + +++ D + A +
Sbjct: 1385 EVKRKLQKDLEGLSQRHEEKVAAYDKLEKTKTRLQQELD-DLLVDLDHQRQSACNLEKKQ 1443
Query: 166 LSISKSLKESEALPEKEGEELGEGERPEEDAAALELSSDEAVEVEEVIEESRAERIKRSG 225
+ L E + + K EE E + LS A+E E + +++ ER+ +
Sbjct: 1444 KKFDQLLAEEKTISAKYAEERDRAEAEAREKETKALSLARALE-EAMEQKAELERLNKQF 1502
Query: 226 LRRVDDFKKAFSKEKMEKTKVRTRENLEKTRLKTKENLEKTRHTLEKRMNKLGTRLVPAE 285
++D SK+ + K+ LEK++ LE+++ ++ T+L E
Sbjct: 1503 RTEMEDLMS--SKDDVG---------------KSVHELEKSKRALEQQVEEMKTQL--EE 1543
Query: 286 RREKLKTSRD-KLR 298
++L+ + D KLR
Sbjct: 1544 LEDELQATEDAKLR 1557
Score = 33.1 bits (74), Expect = 0.44
Identities = 49/234 (20%), Positives = 93/234 (39%), Gaps = 26/234 (11%)
Query: 58 LDKIIGAVDQIQLTQAQLEERQAEMEGAVQSIQGELSKLGKAHATTSNTVSKLLEKVRKV 117
L++ A ++QL + E + ++E ++ + KL K + +++ + +
Sbjct: 952 LEEEESARQKLQLEKVTTEAKLKKLEEEQIILEDQNCKLAKEKKLLEDRIAEFTTNLTEE 1011
Query: 118 SVNVKTVRGSLERQAGQIKKLEVNEAELLRRRNFKVMIYQDEVKLPAKLS-----ISKSL 172
K++ + I LE E LRR + Q+ K KL +S +
Sbjct: 1012 EEKSKSLAKLKNKHEAMITDLE----ERLRREEKQ---RQELEKTRRKLEGDSTDLSDQI 1064
Query: 173 KESEA--------LPEKEGEELGEGERPEEDAAALELSSDEAVEVEEVIEESRAERIKRS 224
E +A L +KE E R EE+AA ++ + E+E I E + +
Sbjct: 1065 AELQAQIAELKMQLAKKEEELQAALARVEEEAAQKNMALKKIRELESQISELQEDLESER 1124
Query: 225 GLRRVDDFKKAFSKEKMEKTKVRTRENLEKT------RLKTKENLEKTRHTLEK 272
R + +K E++E K + L+ T R K ++ + + TLE+
Sbjct: 1125 ASRNKAEKQKRDLGEELEALKTELEDTLDSTAAQQELRSKREQEVNILKKTLEE 1178
>gi|153791586 myosin, heavy chain 2, skeletal muscle, adult [Homo
sapiens]
Length = 1941
Score = 45.8 bits (107), Expect = 7e-05
Identities = 67/324 (20%), Positives = 141/324 (43%), Gaps = 41/324 (12%)
Query: 45 KSDQVNGVLVLSLLDKIIGAVDQIQLTQAQLEERQAEMEGAVQSIQGELSKLGKAHATTS 104
+ D+VN + + K+ VD ++ + Q ++ + ++E A + ++G+L ++
Sbjct: 1019 EEDKVNTLTKAKI--KLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESIMDIE 1076
Query: 105 NTVSKLLEKVRKVSVNVKTVRGSLERQAGQIKKLEVNEAELLRRRNFKVMIYQDEVKLPA 164
N +L EK++K + ++ +E + +L+ EL R + E A
Sbjct: 1077 NEKQQLDEKLKKKEFEISNLQSKIEDEQALGIQLQKKIKELQARIEELEEEIEAERASRA 1136
Query: 165 KL-----SISKSLKE-SEALPEKEG---EELGEGERPEEDAAALELSSDEAVEVEE---- 211
K +S+ L+E SE L E G ++ ++ E + + +EA E
Sbjct: 1137 KAEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAA 1196
Query: 212 VIEESRAERIKRSGLRRVDDFKKAFSKEKMEKTKVRTRENLE------KTRLKTKENLEK 265
+ + A+ + G ++D+ ++ K+K+EK K + ++ +T K K NLEK
Sbjct: 1197 TLRKKHADSVAELG-EQIDNLQRV--KQKLEKEKSEMKMEIDDLASNVETVSKAKGNLEK 1253
Query: 266 TRHTLEKRMNKLGTRLVPAER--------REKLKTSRDKLRKSFTPDHVV---YARSKTA 314
TLE ++++L ++ +R R +L+T + + + +R K A
Sbjct: 1254 MCRTLEDQLSELKSKEEEQQRLINDLTAQRGRLQTESGEFSRQLDEKEALVSQLSRGKQA 1313
Query: 315 VYKVPPFTFHVKKIREGQVEVLKA 338
FT +++++ E +KA
Sbjct: 1314 ------FTQQIEELKRQLEEEIKA 1331
Score = 35.4 bits (80), Expect = 0.089
Identities = 42/244 (17%), Positives = 109/244 (44%), Gaps = 19/244 (7%)
Query: 67 QIQLTQAQLEERQAEMEGAVQSIQGELSKLGKAHATTSNTVSKLLEKVRKVSVNVKTVRG 126
++ + +LE+ +E++ + ++ L+K+ K T N V L E++ + +
Sbjct: 941 ELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDETI----A 996
Query: 127 SLERQAGQIKKLEVNEAELLRRRNFKVMIYQDEVKLPAKLSISKSLKESEALPEKEGEEL 186
L ++ +++ + L+ KV AK+ + + + + E E+E +
Sbjct: 997 KLTKEKKALQEAHQQTLDDLQAEEDKV-----NTLTKAKIKLEQQVDDLEGSLEQEKKLR 1051
Query: 187 GEGERPEEDAAA-LELSSDEAVEVE----EVIEESRAERIKRSGLRRVDDFKKAFS---K 238
+ ER + L+L+ + +++E ++ E+ + + + S L+ + ++A +
Sbjct: 1052 MDLERAKRKLEGDLKLAQESIMDIENEKQQLDEKLKKKEFEISNLQSKIEDEQALGIQLQ 1111
Query: 239 EKMEKTKVRTRENLEKTRLK--TKENLEKTRHTLEKRMNKLGTRLVPAERREKLKTSRDK 296
+K+++ + R E E+ + ++ EK R L + + ++ RL A + +K
Sbjct: 1112 KKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQIEMNK 1171
Query: 297 LRKS 300
R++
Sbjct: 1172 KREA 1175
>gi|153792663 myosin, heavy chain 2, skeletal muscle, adult [Homo
sapiens]
Length = 1941
Score = 45.8 bits (107), Expect = 7e-05
Identities = 67/324 (20%), Positives = 141/324 (43%), Gaps = 41/324 (12%)
Query: 45 KSDQVNGVLVLSLLDKIIGAVDQIQLTQAQLEERQAEMEGAVQSIQGELSKLGKAHATTS 104
+ D+VN + + K+ VD ++ + Q ++ + ++E A + ++G+L ++
Sbjct: 1019 EEDKVNTLTKAKI--KLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESIMDIE 1076
Query: 105 NTVSKLLEKVRKVSVNVKTVRGSLERQAGQIKKLEVNEAELLRRRNFKVMIYQDEVKLPA 164
N +L EK++K + ++ +E + +L+ EL R + E A
Sbjct: 1077 NEKQQLDEKLKKKEFEISNLQSKIEDEQALGIQLQKKIKELQARIEELEEEIEAERASRA 1136
Query: 165 KL-----SISKSLKE-SEALPEKEG---EELGEGERPEEDAAALELSSDEAVEVEE---- 211
K +S+ L+E SE L E G ++ ++ E + + +EA E
Sbjct: 1137 KAEKQRSDLSRELEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAA 1196
Query: 212 VIEESRAERIKRSGLRRVDDFKKAFSKEKMEKTKVRTRENLE------KTRLKTKENLEK 265
+ + A+ + G ++D+ ++ K+K+EK K + ++ +T K K NLEK
Sbjct: 1197 TLRKKHADSVAELG-EQIDNLQRV--KQKLEKEKSEMKMEIDDLASNVETVSKAKGNLEK 1253
Query: 266 TRHTLEKRMNKLGTRLVPAER--------REKLKTSRDKLRKSFTPDHVV---YARSKTA 314
TLE ++++L ++ +R R +L+T + + + +R K A
Sbjct: 1254 MCRTLEDQLSELKSKEEEQQRLINDLTAQRGRLQTESGEFSRQLDEKEALVSQLSRGKQA 1313
Query: 315 VYKVPPFTFHVKKIREGQVEVLKA 338
FT +++++ E +KA
Sbjct: 1314 ------FTQQIEELKRQLEEEIKA 1331
Score = 35.4 bits (80), Expect = 0.089
Identities = 42/244 (17%), Positives = 109/244 (44%), Gaps = 19/244 (7%)
Query: 67 QIQLTQAQLEERQAEMEGAVQSIQGELSKLGKAHATTSNTVSKLLEKVRKVSVNVKTVRG 126
++ + +LE+ +E++ + ++ L+K+ K T N V L E++ + +
Sbjct: 941 ELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDETI----A 996
Query: 127 SLERQAGQIKKLEVNEAELLRRRNFKVMIYQDEVKLPAKLSISKSLKESEALPEKEGEEL 186
L ++ +++ + L+ KV AK+ + + + + E E+E +
Sbjct: 997 KLTKEKKALQEAHQQTLDDLQAEEDKV-----NTLTKAKIKLEQQVDDLEGSLEQEKKLR 1051
Query: 187 GEGERPEEDAAA-LELSSDEAVEVE----EVIEESRAERIKRSGLRRVDDFKKAFS---K 238
+ ER + L+L+ + +++E ++ E+ + + + S L+ + ++A +
Sbjct: 1052 MDLERAKRKLEGDLKLAQESIMDIENEKQQLDEKLKKKEFEISNLQSKIEDEQALGIQLQ 1111
Query: 239 EKMEKTKVRTRENLEKTRLK--TKENLEKTRHTLEKRMNKLGTRLVPAERREKLKTSRDK 296
+K+++ + R E E+ + ++ EK R L + + ++ RL A + +K
Sbjct: 1112 KKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELEEISERLEEAGGATSAQIEMNK 1171
Query: 297 LRKS 300
R++
Sbjct: 1172 KREA 1175
>gi|110815815 centlein isoform 1 [Homo sapiens]
Length = 1406
Score = 45.8 bits (107), Expect = 7e-05
Identities = 64/286 (22%), Positives = 123/286 (43%), Gaps = 40/286 (13%)
Query: 66 DQIQLTQAQLEERQAE-MEGAVQSIQGELSKLGKAHATTSNTVSKLLEKVRKVSVNVKT- 123
D +L + + ER+ E +E A+Q E +L AH + L R V +K
Sbjct: 524 DSEELQKLRKAERKIENLEKALQLKSQENDELRDAHEKRKERLQMLQTNYRAVKEQLKQW 583
Query: 124 VRGSLERQAGQIKKLEV------------NEAELLRRRNFKVMIYQ-------DEVKLPA 164
GS + +IK+ + NE +R N ++MI + DE+K+
Sbjct: 584 EEGSGMTEIRKIKRADPQQLRQEDSDAVWNELAYFKRENQELMIQKMNLEEELDELKVHI 643
Query: 165 KLSISKSLKESEALPEKEGEEL---GEGER-----PEEDAAA-LELSSDEAVEVEEVIE- 214
+ + + + + E+ E+L GE + PE++ LE + + E+E ++
Sbjct: 644 SIDKAAIQELNRCVAERREEQLFRSGEDDEVKRSTPEKNGKEMLEQTLQKVTELENRLKS 703
Query: 215 -ESRAERIKRSG--LRRVDDFKKAFSKEKMEKTKVRTRENLEKTRLKTKENLEKTRHTLE 271
E R+ ++K L + +DF K+ K++ E TRE + +K +++EK L+
Sbjct: 704 FEKRSRKLKEGNKKLMKENDFLKSLLKQQQED--TETREKELEQIIKGSKDVEKENTELQ 761
Query: 272 KRMNKLGTRLVPAERR----EKLKTSRDKLRKSFTPDHVVYARSKT 313
++++L T + R+ L+ ++L H R+K+
Sbjct: 762 VKISELETEVTSLRRQVAEANALRNENEELINPMEKSHQSADRAKS 807
Score = 30.0 bits (66), Expect = 3.7
Identities = 64/340 (18%), Positives = 135/340 (39%), Gaps = 46/340 (13%)
Query: 41 EELIKSDQVNGVLVLSLLDKIIGAVDQIQLTQAQLEERQAEMEGAVQSIQGELSK----- 95
+ L+K Q + L++II ++ +L+ + +E+E V S++ ++++
Sbjct: 726 KSLLKQQQEDTETREKELEQIIKGSKDVEKENTELQVKISELETEVTSLRRQVAEANALR 785
Query: 96 ---------LGKAHATTSNTVSKLLE-KVRKVSVNVKTVRGSLERQAGQIKKLEVNEAEL 145
+ K+H + S++ KVR + KT ++ +A + K V
Sbjct: 786 NENEELINPMEKSHQSADRAKSEMATMKVRSGRYDCKTTMTKVKFKAAK-KNCSVGRHHT 844
Query: 146 LRRRNFKVM--IYQDEVKLPAKLSISKSLKESEA-----------------LPEKEGEEL 186
+ + KVM ++++ K +S+S +SEA P ++G++
Sbjct: 845 VLNHSIKVMSNVFENLSK-DGWEDVSESSSDSEAQTSQTLGTIIVETSQKISPTEDGKDQ 903
Query: 187 GEGERPEEDAAALELSSDEAVEVEEVIE-ESRAERIKRSGLRRVDDFKKAFSKEKMEKTK 245
E + P ED+ + E V+ I+ ++ + ++ KK +K T
Sbjct: 904 KESD-PTEDS---QTQGKEIVQTYLNIDGKTPKDYFHDKNAKKPTFQKKNCKMQKSSHTA 959
Query: 246 VRTRENLEKTRLKTKENLEKTRHTLEKRMNKLGTRLVPAERREK-----LKTSRDKLRKS 300
V TR N EK + T + L +R+ L + + +K +K ++ K
Sbjct: 960 VPTRVNREKYKNITAQKSSSNIILLRERIISLQQQNSVLQNAKKTAELSVKEYKEVNEKL 1019
Query: 301 FTPDHVVYARSKTAVYKVPPFTFHVKKIREGQVEVLKATE 340
V R +T+ + + +R+ + ++LK E
Sbjct: 1020 LHQQQVSDQRFQTSRQTIKKLNLDLAGLRKEKEDLLKKLE 1059
>gi|156766047 GRB10 interacting GYF protein 2 isoform c [Homo
sapiens]
Length = 1293
Score = 45.4 bits (106), Expect = 9e-05
Identities = 49/230 (21%), Positives = 99/230 (43%), Gaps = 32/230 (13%)
Query: 92 ELSKLGKAHATTSNTVSKLLEKVRKVSVNVKTVRGSLERQAGQIKKLEVNEAELLRRRNF 151
+L +L KA A +KL ++ R+ + K +RQ ++L + E+LRR+
Sbjct: 719 QLQQLEKAKA------AKLEQERREAEMRAKREEEERKRQ----EELRRQQEEILRRQ-- 766
Query: 152 KVMIYQDEVKLPAKLSISKSLKESEALPEKEGEELGEGERPEEDAAALELSSDEAVEVEE 211
Q+E + +E E L ++ EE +R +E A + +E + EE
Sbjct: 767 -----QEE---------ERKRREEEELARRKQEEALRRQREQEIALRRQREEEERQQQEE 812
Query: 212 VIEESRAERIKRSGLRRVDDFKKAFSKE--KMEKTKVRTRENLEKTRLKTKENLEKTRHT 269
+ R + R+ ++ + +E K + + + LE+ RL+ +E + RH
Sbjct: 813 ALRRLEERRREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHE 872
Query: 270 LEKRMNKLGTRLVPAERREKLKTSRDKLRKSFTPDHVVYARSKTAVYKVP 319
E+R K + +R+++L R + +++ + + A K+P
Sbjct: 873 EEERKRK----ELEVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLP 918
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.307 0.127 0.328
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 13,739,729
Number of Sequences: 37866
Number of extensions: 633556
Number of successful extensions: 5685
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 83
Number of HSP's successfully gapped in prelim test: 594
Number of HSP's that attempted gapping in prelim test: 4401
Number of HSP's gapped (non-prelim): 1526
length of query: 390
length of database: 18,247,518
effective HSP length: 104
effective length of query: 286
effective length of database: 14,309,454
effective search space: 4092503844
effective search space used: 4092503844
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.6 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.