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Search of human proteins with 126273569
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|126273569 plasma carboxypeptidase B2 isoform a preproprotein
[Homo sapiens]
(423 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|126273569 plasma carboxypeptidase B2 isoform a preproprotein ... 872 0.0
gi|126273559 plasma carboxypeptidase B2 isoform b [Homo sapiens] 692 0.0
gi|54607080 pancreatic carboxypeptidase B1 preproprotein [Homo s... 344 1e-94
gi|221316749 carboxypeptidase A3 precursor [Homo sapiens] 330 2e-90
gi|188536067 carboxypeptidase A6 isoform 1 precursor [Homo sapiens] 318 6e-87
gi|27436871 carboxypeptidase O [Homo sapiens] 306 3e-83
gi|217416390 carboxypeptidase A2 (pancreatic) precursor [Homo sa... 271 8e-73
gi|188536053 carboxypeptidase A5 isoform 1 [Homo sapiens] 264 1e-70
gi|188536051 carboxypeptidase A5 isoform 1 [Homo sapiens] 264 1e-70
gi|61743916 carboxypeptidase A4 preproprotein [Homo sapiens] 258 9e-69
gi|4502997 carboxypeptidase A1 precursor [Homo sapiens] 257 2e-68
gi|188536055 carboxypeptidase A5 isoform 2 [Homo sapiens] 194 1e-49
gi|188536069 carboxypeptidase A6 isoform 2 [Homo sapiens] 127 2e-29
gi|22202611 carboxypeptidase D precursor [Homo sapiens] 59 1e-08
gi|9994201 carboxypeptidase X, member 1 precursor [Homo sapiens] 46 6e-05
gi|223005864 carboxypeptidase X (M14 family), member 2 [Homo sap... 42 8e-04
gi|4503009 carboxypeptidase E preproprotein [Homo sapiens] 38 0.020
gi|4503011 carboxypeptidase N, polypeptide 1 precursor [Homo sap... 37 0.034
gi|53832021 carboxypeptidase M precursor [Homo sapiens] 37 0.034
gi|38327526 carboxypeptidase M precursor [Homo sapiens] 37 0.034
gi|6631081 carboxypeptidase M precursor [Homo sapiens] 37 0.034
gi|34740327 zinc finger protein 804A [Homo sapiens] 33 0.49
gi|94400919 WD repeat domain 90 [Homo sapiens] 31 2.4
gi|10835079 gap junction protein, beta 5, 31.1kDa [Homo sapiens] 30 4.1
gi|4759248 tryptophan hydroxylase 1 [Homo sapiens] 30 5.4
gi|89191868 von Willebrand factor preproprotein [Homo sapiens] 29 9.2
gi|38348244 hypothetical protein LOC200844 [Homo sapiens] 29 9.2
>gi|126273569 plasma carboxypeptidase B2 isoform a preproprotein
[Homo sapiens]
Length = 423
Score = 872 bits (2253), Expect = 0.0
Identities = 423/423 (100%), Positives = 423/423 (100%)
Query: 1 MKLCSLAVLVPIVLFCEQHVFAFQSGQVLAALPRTSRQVQVLQNLTTTYEIVLWQPVTAD 60
MKLCSLAVLVPIVLFCEQHVFAFQSGQVLAALPRTSRQVQVLQNLTTTYEIVLWQPVTAD
Sbjct: 1 MKLCSLAVLVPIVLFCEQHVFAFQSGQVLAALPRTSRQVQVLQNLTTTYEIVLWQPVTAD 60
Query: 61 LIVKKKQVHFFVNASDVDNVKAHLNVSGIPCSVLLADVEDLIQQQISNDTVSPRASASYY 120
LIVKKKQVHFFVNASDVDNVKAHLNVSGIPCSVLLADVEDLIQQQISNDTVSPRASASYY
Sbjct: 61 LIVKKKQVHFFVNASDVDNVKAHLNVSGIPCSVLLADVEDLIQQQISNDTVSPRASASYY 120
Query: 121 EQYHSLNEIYSWIEFITERHPDMLTKIHIGSSFEKYPLYVLKVSGKEQAAKNAIWIDCGI 180
EQYHSLNEIYSWIEFITERHPDMLTKIHIGSSFEKYPLYVLKVSGKEQAAKNAIWIDCGI
Sbjct: 121 EQYHSLNEIYSWIEFITERHPDMLTKIHIGSSFEKYPLYVLKVSGKEQAAKNAIWIDCGI 180
Query: 181 HAREWISPAFCLWFIGHITQFYGIIGQYTNLLRLVDFYVMPVVNVDGYDYSWKKNRMWRK 240
HAREWISPAFCLWFIGHITQFYGIIGQYTNLLRLVDFYVMPVVNVDGYDYSWKKNRMWRK
Sbjct: 181 HAREWISPAFCLWFIGHITQFYGIIGQYTNLLRLVDFYVMPVVNVDGYDYSWKKNRMWRK 240
Query: 241 NRSFYANNHCIGTDLNRNFASKHWCEEGASSSSCSETYCGLYPESEPEVKAVASFLRRNI 300
NRSFYANNHCIGTDLNRNFASKHWCEEGASSSSCSETYCGLYPESEPEVKAVASFLRRNI
Sbjct: 241 NRSFYANNHCIGTDLNRNFASKHWCEEGASSSSCSETYCGLYPESEPEVKAVASFLRRNI 300
Query: 301 NQIKAYISMHSYSQHIVFPYSYTRSKSKDHEELSLVASEAVRAIEKTSKNTRYTHGHGSE 360
NQIKAYISMHSYSQHIVFPYSYTRSKSKDHEELSLVASEAVRAIEKTSKNTRYTHGHGSE
Sbjct: 301 NQIKAYISMHSYSQHIVFPYSYTRSKSKDHEELSLVASEAVRAIEKTSKNTRYTHGHGSE 360
Query: 361 TLYLAPGGGDDWIYDLGIKYSFTIELRDTGTYGFLLPERYIKPTCREAFAAVSKIAWHVI 420
TLYLAPGGGDDWIYDLGIKYSFTIELRDTGTYGFLLPERYIKPTCREAFAAVSKIAWHVI
Sbjct: 361 TLYLAPGGGDDWIYDLGIKYSFTIELRDTGTYGFLLPERYIKPTCREAFAAVSKIAWHVI 420
Query: 421 RNV 423
RNV
Sbjct: 421 RNV 423
>gi|126273559 plasma carboxypeptidase B2 isoform b [Homo sapiens]
Length = 360
Score = 692 bits (1785), Expect = 0.0
Identities = 345/383 (90%), Positives = 345/383 (90%), Gaps = 37/383 (9%)
Query: 1 MKLCSLAVLVPIVLFCEQHVFAFQSGQVLAALPRTSRQVQVLQNLTTTYEIVLWQPVTAD 60
MKLCSLAVLVPIVLFCEQHVFAFQSGQVLAALPRTSRQVQVLQNLTTTYEIVLWQPVTAD
Sbjct: 1 MKLCSLAVLVPIVLFCEQHVFAFQSGQVLAALPRTSRQVQVLQNLTTTYEIVLWQPVTAD 60
Query: 61 LIVKKKQVHFFVNASDVDNVKAHLNVSGIPCSVLLADVEDLIQQQISNDTVSPRASASYY 120
LIVKKKQVHFFVNASDVDNVKAHLNVSGIPCSVLLADVEDLIQQQISNDTVSPRASASYY
Sbjct: 61 LIVKKKQVHFFVNASDVDNVKAHLNVSGIPCSVLLADVEDLIQQQISNDTVSPRASASYY 120
Query: 121 EQYHSLNEIYSWIEFITERHPDMLTKIHIGSSFEKYPLYVLKVSGKEQAAKNAIWIDCGI 180
EQYHSLNEIYSWIEFITERHPDMLTKIHIGSSFEKYPLYVLKVSGKEQAAKNAIWIDCGI
Sbjct: 121 EQYHSLNEIYSWIEFITERHPDMLTKIHIGSSFEKYPLYVLKVSGKEQAAKNAIWIDCGI 180
Query: 181 HAREWISPAFCLWFIGHITQFYGIIGQYTNLLRLVDFYVMPVVNVDGYDYSWKKNRMWRK 240
HAREWISPAFCLWFIGH NRMWRK
Sbjct: 181 HAREWISPAFCLWFIGH-------------------------------------NRMWRK 203
Query: 241 NRSFYANNHCIGTDLNRNFASKHWCEEGASSSSCSETYCGLYPESEPEVKAVASFLRRNI 300
NRSFYANNHCIGTDLNRNFASKHWCEEGASSSSCSETYCGLYPESEPEVKAVASFLRRNI
Sbjct: 204 NRSFYANNHCIGTDLNRNFASKHWCEEGASSSSCSETYCGLYPESEPEVKAVASFLRRNI 263
Query: 301 NQIKAYISMHSYSQHIVFPYSYTRSKSKDHEELSLVASEAVRAIEKTSKNTRYTHGHGSE 360
NQIKAYISMHSYSQHIVFPYSYTRSKSKDHEELSLVASEAVRAIEKTSKNTRYTHGHGSE
Sbjct: 264 NQIKAYISMHSYSQHIVFPYSYTRSKSKDHEELSLVASEAVRAIEKTSKNTRYTHGHGSE 323
Query: 361 TLYLAPGGGDDWIYDLGIKYSFT 383
TLYLAPGGGDDWIYDLGIKYS T
Sbjct: 324 TLYLAPGGGDDWIYDLGIKYSVT 346
>gi|54607080 pancreatic carboxypeptidase B1 preproprotein [Homo
sapiens]
Length = 417
Score = 344 bits (882), Expect = 1e-94
Identities = 175/422 (41%), Positives = 258/422 (61%), Gaps = 7/422 (1%)
Query: 3 LCSLAVLVPIVLFCEQHVFA-FQSGQVLAALPRTSRQVQVLQNLTTTYEIVLWQPVTADL 61
+ +L VLV + L H F+ +V + +++ L +T +I W+P +
Sbjct: 1 MLALLVLVTVALASAHHGGEHFEGEKVFRVNVEDENHINIIRELASTTQIDFWKPDSVTQ 60
Query: 62 IVKKKQVHFFVNASDVDNVKAHLNVSGIPCSVLLADVEDLIQQQISNDTVSPRASASYYE 121
I V F V A D V+ L + + VL++++ ++++ Q + RA+ YE
Sbjct: 61 IKPHSTVDFRVKAEDTVTVENVLKQNELQYKVLISNLRNVVEAQFDSRV---RATGHSYE 117
Query: 122 QYHSLNEIYSWIEFITERHPDMLTKIHIGSSFEKYPLYVLKVSGKEQAAKNAIWIDCGIH 181
+Y+ I +W + + +P ++++ IG++FE +Y+LKV GK K AI++DCG H
Sbjct: 118 KYNKWETIEAWTQQVATENPALISRSVIGTTFEGRAIYLLKV-GKAGQNKPAIFMDCGFH 176
Query: 182 AREWISPAFCLWFIGHITQFYGIIGQYTNLLRLVDFYVMPVVNVDGYDYSWKKNRMWRKN 241
AREWISPAFC WF+ + YG Q T LL +DFYV+PV+N+DGY Y+W K+R WRK
Sbjct: 177 AREWISPAFCQWFVREAVRTYGREIQVTELLDKLDFYVLPVLNIDGYIYTWTKSRFWRKT 236
Query: 242 RSFYANNHCIGTDLNRNFASKHWCEEGASSSSCSETYCGLYPESEPEVKAVASFLRRNIN 301
RS + + CIGTD NRNF WCE GAS + C ETYCG ESE E KA+A F+R ++
Sbjct: 237 RSTHTGSSCIGTDPNRNF-DAGWCEIGASRNPCDETYCGPAAESEKETKALADFIRNKLS 295
Query: 302 QIKAYISMHSYSQHIVFPYSYTRSKSKDHEELSLVASEAVRAIEKTSKNTRYTHGHGSET 361
IKAY+++HSYSQ +++PYSY +++ EL+ +A V+ + + T+YT+G G+ T
Sbjct: 296 SIKAYLTIHSYSQMMIYPYSYAYKLGENNAELNALAKATVKEL-ASLHGTKYTYGPGATT 354
Query: 362 LYLAPGGGDDWIYDLGIKYSFTIELRDTGTYGFLLPERYIKPTCREAFAAVSKIAWHVIR 421
+Y A GG DDW YD GI+YSFT ELRDTG YGFLLPE I+ TC E F A+ +A +V+
Sbjct: 355 IYPAAGGSDDWAYDQGIRYSFTFELRDTGRYGFLLPESQIRATCEETFLAIKYVASYVLE 414
Query: 422 NV 423
++
Sbjct: 415 HL 416
>gi|221316749 carboxypeptidase A3 precursor [Homo sapiens]
Length = 417
Score = 330 bits (845), Expect = 2e-90
Identities = 171/421 (40%), Positives = 255/421 (60%), Gaps = 10/421 (2%)
Query: 6 LAVLVPIVLFCEQHVFA---FQSGQVLAALPRTSRQVQVLQNLTTTYEIVLWQPVTADLI 62
+ +++P+ L A F +V P+ +Q ++++L T E+ W P +
Sbjct: 1 MRLILPVGLIATTLAIAPVRFDREKVFRVKPQDEKQADIIKDLAKTNELDFWYPGATHHV 60
Query: 63 VKKKQVHFFVNASDVDNVKAHLNVSGIPCSVLLADVEDLIQQQIS-NDTVSPRASASYYE 121
V F V+ + +++ L+ + + +L+ D+++ I++Q + + R S Y
Sbjct: 61 AANMMVDFRVSEKESQAIQSALDQNKMHYEILIHDLQEEIEKQFDVKEDIPGRHS---YA 117
Query: 122 QYHSLNEIYSWIEFITERHPDMLTKIHIGSSFEKYPLYVLKVSGKEQAAKNAIWIDCGIH 181
+Y++ +I +W E + +++P+M+++I IGS+ E PLYVLK+ K + K AI+ DCGIH
Sbjct: 118 KYNNWEKIVAWTEKMMDKYPEMVSRIKIGSTVEDNPLYVLKIGEKNERRK-AIFTDCGIH 176
Query: 182 AREWISPAFCLWFIGHITQFYGIIGQYTNLLRLVDFYVMPVVNVDGYDYSWKKNRMWRKN 241
AREW+SPAFC WF+ T+ YG T LL ++FY++PV NVDGY +SW KNRMWRKN
Sbjct: 177 AREWVSPAFCQWFVYQATKTYGRNKIMTKLLDRMNFYILPVFNVDGYIWSWTKNRMWRKN 236
Query: 242 RSFYANNHCIGTDLNRNFASKHWCEEGASSSSCSETYCGLYPESEPEVKAVASFLRRNIN 301
RS N+ CIGTDLNRNF + W ++ C++ Y G PESE E KAV +F+R ++N
Sbjct: 237 RSKNQNSKCIGTDLNRNF-NASWNSIPNTNDPCADNYRGSAPESEKETKAVTNFIRSHLN 295
Query: 302 QIKAYISMHSYSQHIVFPYSYTRSKSKDHEELSLVASEAVRAIEKTSKNTRYTHGHGSET 361
+IK YI+ HSYSQ ++FPY YT +HE+L+ VA + T TRY +G T
Sbjct: 296 EIKVYITFHSYSQMLLFPYGYTSKLPPNHEDLAKVAKIGTDVL-STRYETRYIYGPIEST 354
Query: 362 LYLAPGGGDDWIYDLGIKYSFTIELRDTGTYGFLLPERYIKPTCREAFAAVSKIAWHVIR 421
+Y G DW YDLGIK++F ELRD G +GFLLPE IKPTCRE AV IA ++++
Sbjct: 355 IYPISGSSLDWAYDLGIKHTFAFELRDKGKFGFLLPESRIKPTCRETMLAVKFIAKYILK 414
Query: 422 N 422
+
Sbjct: 415 H 415
>gi|188536067 carboxypeptidase A6 isoform 1 precursor [Homo sapiens]
Length = 437
Score = 318 bits (815), Expect = 6e-87
Identities = 161/401 (40%), Positives = 232/401 (57%), Gaps = 5/401 (1%)
Query: 23 FQSGQVLAALPRTSRQVQVLQNLTTTYEIVLWQPVTADLIVKKKQVHFFVNASDVDNVKA 82
+ +V+ +P+T + L+ ++ ++ LWQP + + + + + + A
Sbjct: 37 YAGDKVIRFIPKTEEEAYALKKISYQLKVDLWQPSSISYVSEGTVTDVHIPQNGSRALLA 96
Query: 83 HLNVSGIPCSVLLADVEDLIQQQISNDTVSPRASAS--YYEQYHSLNEIYSWIEFITERH 140
L + I VL+ D++ +++ S T R S S YE YHSL EI +W+ + + H
Sbjct: 97 FLQEANIQYKVLIEDLQKTLEKGSSLHTQRNRRSLSGYNYEVYHSLEEIQNWMHHLNKTH 156
Query: 141 PDMLTKIHIGSSFEKYPLYVLKVSGKEQAAKNAIWIDCGIHAREWISPAFCLWFIGHITQ 200
++ IG S+E L++LK+ G+ K A+WIDCGIHAREWI PAFC WF+
Sbjct: 157 SGLIHMFSIGRSYEGRSLFILKL-GRRSRLKRAVWIDCGIHAREWIGPAFCQWFVKEALL 215
Query: 201 FYGIIGQYTNLLRLVDFYVMPVVNVDGYDYSWKKNRMWRKNRSFYANNHCIGTDLNRNFA 260
Y +L + FY+MPV NVDGY +SW +R WRK RS + C G D NRN+
Sbjct: 216 TYKSDPAMRKMLNHLYFYIMPVFNVDGYHFSWTNDRFWRKTRSRNSRFRCRGVDANRNWK 275
Query: 261 SKHWCEEGASSSSCSETYCGLYPESEPEVKAVASFLRRNINQIKAYISMHSYSQHIVFPY 320
K WC+EGAS C +TYCG +PESEPEVKAVA+FLR++ I+AY+S H+Y+Q +++PY
Sbjct: 276 VK-WCDEGASMHPCDDTYCGPFPESEPEVKAVANFLRKHRKHIRAYLSFHAYAQMLLYPY 334
Query: 321 SYTRSKSKDHEELSLVASEAVRAIEKTSKNTRYTHGHGSETLYLAPGGGDDWIYDLGIKY 380
SY + + + A +AV A++ RY +G S TLY++ G DW Y GI Y
Sbjct: 335 SYKYATIPNFRCVESAAYKAVNALQSV-YGVRYRYGPASTTLYVSSGSSMDWAYKNGIPY 393
Query: 381 SFTIELRDTGTYGFLLPERYIKPTCREAFAAVSKIAWHVIR 421
+F ELRDTG +GFLLPE IKPTC E AV I H+++
Sbjct: 394 AFAFELRDTGYFGFLLPEMLIKPTCTETMLAVKNITMHLLK 434
>gi|27436871 carboxypeptidase O [Homo sapiens]
Length = 374
Score = 306 bits (783), Expect = 3e-83
Identities = 145/314 (46%), Positives = 205/314 (65%), Gaps = 3/314 (0%)
Query: 103 QQQISNDTVSPRASASY-YEQYHSLNEIYSWIEFITERHPDMLTKIHIGSSFEKYPLYVL 161
+Q+I + +VSP + +Y Y YH + EIY W+ I+E++ +++T+ +G ++E +P+Y L
Sbjct: 29 RQEIVDKSVSPWSLETYSYNIYHPMGEIYEWMREISEKYKEVVTQHFLGVTYETHPMYYL 88
Query: 162 KVSGKEQAAKNAIWIDCGIHAREWISPAFCLWFIGHITQFYGIIGQYTNLLRLVDFYVMP 221
K+S K IW+DCGIHAREWI+PAFC WF+ I Q + LLR +DFYV+P
Sbjct: 89 KISQPSGNPKKIIWMDCGIHAREWIAPAFCQWFVKEILQNHKDNSSIRKLLRNLDFYVLP 148
Query: 222 VVNVDGYDYSWKKNRMWRKNRSFYANNHCIGTDLNRNFASKHWCEEGASSSSCSETYCGL 281
V+N+DGY Y+W +R+WRK+RS + N C GTDLNRNF + WC GAS + +T+CG
Sbjct: 149 VLNIDGYIYTWTTDRLWRKSRSPHNNGTCFGTDLNRNF-NASWCSIGASRNCQDQTFCGT 207
Query: 282 YPESEPEVKAVASFLRRNINQIKAYISMHSYSQHIVFPYSYTRSKSKDHEELSLVASEAV 341
P SEPE KAVASF+ + I +++MHSY Q I+ PY YT++KS +H E+ V +A
Sbjct: 208 GPVSEPETKAVASFIESKKDDILCFLTMHSYGQLILTPYGYTKNKSSNHPEMIQVGQKAA 267
Query: 342 RAIEKTSKNTRYTHGHGSETLYLAPGGGDDWIYDLGIKYSFTIELRDTGTYGFLLPERYI 401
A+ K T Y G ++ LY + G DW D+GI +S+T ELRD+GTYGF+LPE I
Sbjct: 268 NAL-KAKYGTNYRVGSSADILYASSGSSRDWARDIGIPFSYTFELRDSGTYGFVLPEAQI 326
Query: 402 KPTCREAFAAVSKI 415
+PTC E AV +
Sbjct: 327 QPTCEETMEAVLSV 340
>gi|217416390 carboxypeptidase A2 (pancreatic) precursor [Homo
sapiens]
Length = 419
Score = 271 bits (693), Expect = 8e-73
Identities = 158/402 (39%), Positives = 226/402 (56%), Gaps = 14/402 (3%)
Query: 23 FQSGQVLAALPRTSRQVQVLQNLTTTYEIVL--WQPVTADLIVKKKQVHFFVNASDVDNV 80
F QVL +P Q++ L L + L W+ T + H V +V V
Sbjct: 22 FVGDQVLEIVPSNEEQIKNLLQLEAQEHLQLDFWKSPTTP----GETAHVRVPFVNVQAV 77
Query: 81 KAHLNVSGIPCSVLLADVEDLIQQQISNDTVSPRASAS---YYEQYHSLNEIYSWIEFIT 137
K L GI S+++ DV+ L+ ++ + R S + YH+L EI ++ +
Sbjct: 78 KVFLESQGIAYSIMIEDVQVLLDKENEEMLFNRRRERSGNFNFGAYHTLEEISQEMDNLV 137
Query: 138 ERHPDMLTKIHIGSSFEKYPLYVLKVSGKEQAAKNAIWIDCGIHAREWISPAFCLWFIGH 197
HP +++K++IGSSFE P+ VLK S K AIW+D GIHAREW++ A LW
Sbjct: 138 AEHPGLVSKVNIGSSFENRPMNVLKFS--TGGDKPAIWLDAGIHAREWVTQATALWTANK 195
Query: 198 ITQFYGIIGQYTNLLRLVDFYVMPVVNVDGYDYSWKKNRMWRKNRSFYANNHCIGTDLNR 257
I YG T++L +D +++PV N DGY +S KNRMWRK RS + + C+G D NR
Sbjct: 196 IVSDYGKDPSITSILDALDIFLLPVTNPDGYVFSQTKNRMWRKTRSKVSGSLCVGVDPNR 255
Query: 258 NFASKHWCEEGASSSSCSETYCGLYPESEPEVKAVASFLRRNINQIKAYISMHSYSQHIV 317
N+ + GASS+ CS++Y G SE EVK++ F++ + ++KA+I++HSYSQ ++
Sbjct: 256 NW-DAGFGGPGASSNPCSDSYHGPSANSEVEVKSIVDFIKSH-GKVKAFITLHSYSQLLM 313
Query: 318 FPYSYTRSKSKDHEELSLVASEAVRAIEKTSKNTRYTHGHGSETLYLAPGGGDDWIYDLG 377
FPY Y +K D +ELS VA +A +++ ++ T+Y G +Y A GG DW YD G
Sbjct: 314 FPYGYKCTKLDDFDELSEVAQKAAQSL-RSLHGTKYKVGPICSVIYQASGGSIDWSYDYG 372
Query: 378 IKYSFTIELRDTGTYGFLLPERYIKPTCREAFAAVSKIAWHV 419
IKYSF ELRDTG YGFLLP R I PT E + + I HV
Sbjct: 373 IKYSFAFELRDTGRYGFLLPARQILPTAEETWLGLKAIMEHV 414
>gi|188536053 carboxypeptidase A5 isoform 1 [Homo sapiens]
Length = 436
Score = 264 bits (674), Expect = 1e-70
Identities = 156/406 (38%), Positives = 227/406 (55%), Gaps = 14/406 (3%)
Query: 23 FQSGQVLAALPRTSRQVQVLQNLT--TTYEIVLWQPVTADLIVKKKQVHFFVNASDVDNV 80
F QVL L + +Q+ +L +L ++ W+ + +V F S++ ++
Sbjct: 37 FTGDQVLRVLAKDEKQLSLLGDLEGLKPQKVDFWRGPARPSLPVDMRVPF----SELKDI 92
Query: 81 KAHLNVSGIPCSVLLADVEDLIQQQISNDTVSPRASASY----YEQYHSLNEIYSWIEFI 136
KA+L G+ S+++ D++ L+ ++ S R S Y YH+L EIYSWI+
Sbjct: 93 KAYLESHGLAYSIMIKDIQVLLDEERQAMAKSRRLERSTNSFSYSSYHTLEEIYSWIDNF 152
Query: 137 TERHPDMLTKIHIGSSFEKYPLYVLKVSGKEQAAKNAIWIDCGIHAREWISPAFCLWFIG 196
H D+++KI IG+SFE + VLK S + AIWID GIH+REWI+ A +W
Sbjct: 153 VMEHSDIVSKIQIGNSFENQSILVLKFS-TGGSRHPAIWIDTGIHSREWITHATGIWTAN 211
Query: 197 HITQFYGIIGQYTNLLRLVDFYVMPVVNVDGYDYSWKKNRMWRKNRSFYANNHCIGTDLN 256
I YG T++L +D ++ V N DG+ ++ NR+WRKN+S CIG DLN
Sbjct: 212 KIVSDYGKDRVLTDILNAMDIFIELVTNPDGFAFTHSMNRLWRKNKSIRPGIFCIGVDLN 271
Query: 257 RNFASKHWCEEGASSSSCSETYCGLYPESEPEVKAVASFLRRNINQIKAYISMHSYSQHI 316
RN+ S + G++S+ CSETY G P+SEPEV A+ +F+ + N KA IS+HSYSQ +
Sbjct: 272 RNWKS-GFGGNGSNSNPCSETYHGPSPQSEPEVAAIVNFITAHGN-FKALISIHSYSQML 329
Query: 317 VFPYSYTRSKSKDHEELSLVASEAVRAIEKTSKNTRYTHGHGSETLYLAPGGGDDWIYDL 376
++PY + EL +A +AV A+ K Y G S TLY+A G DW YD
Sbjct: 330 MYPYGRLLEPVSNQRELYDLAKDAVEALYKV-HGIEYIFGSISTTLYVASGITVDWAYDS 388
Query: 377 GIKYSFTIELRDTGTYGFLLPERYIKPTCREAFAAVSKIAWHVIRN 422
GIKY+F+ ELRDTG YGFLLP I PT +E + A+ I H + +
Sbjct: 389 GIKYAFSFELRDTGQYGFLLPATQIIPTAQETWMALRTIMEHTLNH 434
>gi|188536051 carboxypeptidase A5 isoform 1 [Homo sapiens]
Length = 436
Score = 264 bits (674), Expect = 1e-70
Identities = 156/406 (38%), Positives = 227/406 (55%), Gaps = 14/406 (3%)
Query: 23 FQSGQVLAALPRTSRQVQVLQNLT--TTYEIVLWQPVTADLIVKKKQVHFFVNASDVDNV 80
F QVL L + +Q+ +L +L ++ W+ + +V F S++ ++
Sbjct: 37 FTGDQVLRVLAKDEKQLSLLGDLEGLKPQKVDFWRGPARPSLPVDMRVPF----SELKDI 92
Query: 81 KAHLNVSGIPCSVLLADVEDLIQQQISNDTVSPRASASY----YEQYHSLNEIYSWIEFI 136
KA+L G+ S+++ D++ L+ ++ S R S Y YH+L EIYSWI+
Sbjct: 93 KAYLESHGLAYSIMIKDIQVLLDEERQAMAKSRRLERSTNSFSYSSYHTLEEIYSWIDNF 152
Query: 137 TERHPDMLTKIHIGSSFEKYPLYVLKVSGKEQAAKNAIWIDCGIHAREWISPAFCLWFIG 196
H D+++KI IG+SFE + VLK S + AIWID GIH+REWI+ A +W
Sbjct: 153 VMEHSDIVSKIQIGNSFENQSILVLKFS-TGGSRHPAIWIDTGIHSREWITHATGIWTAN 211
Query: 197 HITQFYGIIGQYTNLLRLVDFYVMPVVNVDGYDYSWKKNRMWRKNRSFYANNHCIGTDLN 256
I YG T++L +D ++ V N DG+ ++ NR+WRKN+S CIG DLN
Sbjct: 212 KIVSDYGKDRVLTDILNAMDIFIELVTNPDGFAFTHSMNRLWRKNKSIRPGIFCIGVDLN 271
Query: 257 RNFASKHWCEEGASSSSCSETYCGLYPESEPEVKAVASFLRRNINQIKAYISMHSYSQHI 316
RN+ S + G++S+ CSETY G P+SEPEV A+ +F+ + N KA IS+HSYSQ +
Sbjct: 272 RNWKS-GFGGNGSNSNPCSETYHGPSPQSEPEVAAIVNFITAHGN-FKALISIHSYSQML 329
Query: 317 VFPYSYTRSKSKDHEELSLVASEAVRAIEKTSKNTRYTHGHGSETLYLAPGGGDDWIYDL 376
++PY + EL +A +AV A+ K Y G S TLY+A G DW YD
Sbjct: 330 MYPYGRLLEPVSNQRELYDLAKDAVEALYKV-HGIEYIFGSISTTLYVASGITVDWAYDS 388
Query: 377 GIKYSFTIELRDTGTYGFLLPERYIKPTCREAFAAVSKIAWHVIRN 422
GIKY+F+ ELRDTG YGFLLP I PT +E + A+ I H + +
Sbjct: 389 GIKYAFSFELRDTGQYGFLLPATQIIPTAQETWMALRTIMEHTLNH 434
>gi|61743916 carboxypeptidase A4 preproprotein [Homo sapiens]
Length = 421
Score = 258 bits (658), Expect = 9e-69
Identities = 151/407 (37%), Positives = 224/407 (55%), Gaps = 13/407 (3%)
Query: 23 FQSGQVLAALPRTSRQVQVLQNLTTTYEIVL--WQPVTADLIVKKKQVHFFVNASDVDNV 80
F QVL R ++ L L + + L W+ ++ + V V + +
Sbjct: 21 FFGDQVLRINVRNGDEISKLSQLVNSNNLKLNFWKSPSSF----NRPVDVLVPSVSLQAF 76
Query: 81 KAHLNVSGIPCSVLLADVEDLIQQQ---ISNDTVSPRASASY-YEQYHSLNEIYSWIEFI 136
K+ L G+ +V + D++ L+ + + ++ R+S ++ Y YHSL IY ++ I
Sbjct: 77 KSFLRSQGLEYAVTIEDLQALLDNEDDEMQHNEGQERSSNNFNYGAYHSLEAIYHEMDNI 136
Query: 137 TERHPDMLTKIHIGSSFEKYPLYVLKVSGKEQAAKNAIWIDCGIHAREWISPAFCLWFIG 196
PD+ ++ IG SFE P+YVLK S + + A+W++ GIH+REWIS A +W
Sbjct: 137 AADFPDLARRVKIGHSFENRPMYVLKFSTGKGVRRPAVWLNAGIHSREWISQATAIWTAR 196
Query: 197 HITQFYGIIGQYTNLLRLVDFYVMPVVNVDGYDYSWKKNRMWRKNRSFYANNHCIGTDLN 256
I Y T++L +D +++PV N DGY Y+ +NR+WRK RS + CIG D N
Sbjct: 197 KIVSDYQRDPAITSILEKMDIFLLPVANPDGYVYTQTQNRLWRKTRSRNPGSSCIGADPN 256
Query: 257 RNFASKHWCEEGASSSSCSETYCGLYPESEPEVKAVASFLRRNINQIKAYISMHSYSQHI 316
RN+ + + +GAS + CSE Y G + SE EVK+V F++++ N K +I +HSYSQ +
Sbjct: 257 RNW-NASFAGKGASDNPCSEVYHGPHANSEVEVKSVVDFIQKHGN-FKGFIDLHSYSQLL 314
Query: 317 VFPYSYTRSKSKDHEELSLVASEAVRAIEKTSKNTRYTHGHGSETLYLAPGGGDDWIYDL 376
++PY Y+ K+ D EEL VA A +A+ S T Y G T+Y A G DW YD
Sbjct: 315 MYPYGYSVKKAPDAEELDKVARLAAKALASVS-GTEYQVGPTCTTVYPASGSSIDWAYDN 373
Query: 377 GIKYSFTIELRDTGTYGFLLPERYIKPTCREAFAAVSKIAWHVIRNV 423
GIK++FT ELRDTGTYGFLLP I PT E + + I HV N+
Sbjct: 374 GIKFAFTFELRDTGTYGFLLPANQIIPTAEETWLGLKTIMEHVRDNL 420
>gi|4502997 carboxypeptidase A1 precursor [Homo sapiens]
Length = 419
Score = 257 bits (656), Expect = 2e-68
Identities = 142/350 (40%), Positives = 210/350 (60%), Gaps = 8/350 (2%)
Query: 77 VDNVKAHLNVSGIPCSVLLADVEDLI---QQQISNDTVSPRASASY-YEQYHSLNEIYSW 132
+ VK L GI ++ DV+ L+ Q+Q+ R++ ++ Y YH+L EIY +
Sbjct: 72 IQAVKIFLESHGISYETMIEDVQSLLDEEQEQMFAFRSRARSTDTFNYATYHTLEEIYDF 131
Query: 133 IEFITERHPDMLTKIHIGSSFEKYPLYVLKVSGKEQAAKNAIWIDCGIHAREWISPAFCL 192
++ + +P +++KI IG+++E P+YVLK S + + AIWID GIH+REW++ A +
Sbjct: 132 LDLLVAENPHLVSKIQIGNTYEGRPIYVLKFS-TGGSKRPAIWIDTGIHSREWVTQASGV 190
Query: 193 WFIGHITQFYGIIGQYTNLLRLVDFYVMPVVNVDGYDYSWKKNRMWRKNRSFYANNHCIG 252
WF ITQ YG +T +L +D ++ V N DG+ ++ NRMWRK RS A + CIG
Sbjct: 191 WFAKKITQDYGQDAAFTAILDTLDIFLEIVTNPDGFAFTHSTNRMWRKTRSHTAGSLCIG 250
Query: 253 TDLNRNFASKHWCEEGASSSSCSETYCGLYPESEPEVKAVASFLRRNINQIKAYISMHSY 312
D NRN+ + GASS+ CSETY G + SE EVK++ F++ + N IKA+IS+HSY
Sbjct: 251 VDPNRNWDAGFGL-SGASSNPCSETYHGKFANSEVEVKSIVDFVKDHGN-IKAFISIHSY 308
Query: 313 SQHIVFPYSYTRSKSKDHEELSLVASEAVRAIEKTSKNTRYTHGHGSETLYLAPGGGDDW 372
SQ +++PY Y D +EL ++ AV A+ + T++ +G + +Y A G DW
Sbjct: 309 SQLLMYPYGYKTEPVPDQDELDQLSKAAVTAL-ASLYGTKFNYGSIIKAIYQASGSTIDW 367
Query: 373 IYDLGIKYSFTIELRDTGTYGFLLPERYIKPTCREAFAAVSKIAWHVIRN 422
Y GIKYSFT ELRDTG YGFLLP I PT +E + A+ I H + +
Sbjct: 368 TYSQGIKYSFTFELRDTGRYGFLLPASQIIPTAKETWLALLTIMEHTLNH 417
>gi|188536055 carboxypeptidase A5 isoform 2 [Homo sapiens]
Length = 403
Score = 194 bits (493), Expect = 1e-49
Identities = 115/317 (36%), Positives = 175/317 (55%), Gaps = 13/317 (4%)
Query: 23 FQSGQVLAALPRTSRQVQVLQNLT--TTYEIVLWQPVTADLIVKKKQVHFFVNASDVDNV 80
F QVL L + +Q+ +L +L ++ W+ + +V F S++ ++
Sbjct: 37 FTGDQVLRVLAKDEKQLSLLGDLEGLKPQKVDFWRGPARPSLPVDMRVPF----SELKDI 92
Query: 81 KAHLNVSGIPCSVLLADVEDLIQQQISNDTVSPRASASY----YEQYHSLNEIYSWIEFI 136
KA+L G+ S+++ D++ L+ ++ S R S Y YH+L EIYSWI+
Sbjct: 93 KAYLESHGLAYSIMIKDIQVLLDEERQAMAKSRRLERSTNSFSYSSYHTLEEIYSWIDNF 152
Query: 137 TERHPDMLTKIHIGSSFEKYPLYVLKVSGKEQAAKNAIWIDCGIHAREWISPAFCLWFIG 196
H D+++KI IG+SFE + VLK S + AIWID GIH+REWI+ A +W
Sbjct: 153 VMEHSDIVSKIQIGNSFENQSILVLKFS-TGGSRHPAIWIDTGIHSREWITHATGIWTAN 211
Query: 197 HITQFYGIIGQYTNLLRLVDFYVMPVVNVDGYDYSWKKNRMWRKNRSFYANNHCIGTDLN 256
I YG T++L +D ++ V N DG+ ++ NR+WRKN+S CIG DLN
Sbjct: 212 KIVSDYGKDRVLTDILNAMDIFIELVTNPDGFAFTHSMNRLWRKNKSIRPGIFCIGVDLN 271
Query: 257 RNFASKHWCEEGASSSSCSETYCGLYPESEPEVKAVASFLRRNINQIKAYISMHSYSQHI 316
RN+ S + G++S+ CSETY G P+SEPEV A+ +F+ + N KA IS+HSYSQ +
Sbjct: 272 RNWKS-GFGGNGSNSNPCSETYHGPSPQSEPEVAAIVNFITAHGN-FKALISIHSYSQML 329
Query: 317 VFPYSYTRSKSKDHEEL 333
++PY + EL
Sbjct: 330 MYPYGRLLEPVSNQREL 346
>gi|188536069 carboxypeptidase A6 isoform 2 [Homo sapiens]
Length = 193
Score = 127 bits (318), Expect = 2e-29
Identities = 60/137 (43%), Positives = 80/137 (58%), Gaps = 2/137 (1%)
Query: 136 ITERHPDMLTKIHIGSSFEKYPLYVLKVSGKEQAAKNAIWIDCGIHAREWISPAFCLWFI 195
+ + H ++ IG S+E L++LK+ G+ K A+WIDCGIHAREWI PAFC WF+
Sbjct: 4 LNKTHSGLIHMFSIGRSYEGRSLFILKL-GRRSRLKRAVWIDCGIHAREWIGPAFCQWFV 62
Query: 196 GHITQFYGIIGQYTNLLRLVDFYVMPVVNVDGYDYSWKKNRMWRKNRSFYANNHCIGTDL 255
Y +L + FY+MPV NVDGY +SW +R WRK RS + C G D
Sbjct: 63 KEALLTYKSDPAMRKMLNHLYFYIMPVFNVDGYHFSWTNDRFWRKTRSRNSRFRCRGVDA 122
Query: 256 NRNFASKHWCEEGASSS 272
NRN+ K WC+ + SS
Sbjct: 123 NRNWKVK-WCDVSSGSS 138
Score = 68.2 bits (165), Expect = 1e-11
Identities = 30/58 (51%), Positives = 37/58 (63%)
Query: 364 LAPGGGDDWIYDLGIKYSFTIELRDTGTYGFLLPERYIKPTCREAFAAVSKIAWHVIR 421
++ G DW Y GI Y+F ELRDTG +GFLLPE IKPTC E AV I H+++
Sbjct: 133 VSSGSSMDWAYKNGIPYAFAFELRDTGYFGFLLPEMLIKPTCTETMLAVKNITMHLLK 190
>gi|22202611 carboxypeptidase D precursor [Homo sapiens]
Length = 1380
Score = 58.5 bits (140), Expect = 1e-08
Identities = 63/283 (22%), Positives = 117/283 (41%), Gaps = 41/283 (14%)
Query: 123 YHSLNEIYSWIEFITERHPDMLTKIHIGSSFEKYPLYVLKVS---GKEQAAKNAIWIDCG 179
+H ++ ++ +P++ +G S E LYV+++S G + +
Sbjct: 503 HHHFPDMEIFLRRFANEYPNITRLYSLGKSVESRELYVMEISDNPGVHEPGEPEFKYIGN 562
Query: 180 IHAREWISPAFCLWFIGHITQFYGIIGQYTNLLRLVDFYVMPVVNVDGYDYSWKKNRMWR 239
+H E + L I ++ + +G + T+L+ ++MP +N DGY+ S + + +
Sbjct: 563 MHGNEVVGRELLLNLIEYLCKNFGTDPEVTDLVHNTRIHLMPSMNPDGYEKSQEGDSI-- 620
Query: 240 KNRSFYANNHCIGTDLNRNFASKHWCEEGASSSSCSETYCGLYPESEPEVKAVASFLRRN 299
S N+ DLNRNF + + + ++PE AV S+++
Sbjct: 621 ---SVIGRNNSNNFDLNRNF---------------PDQFVQITDPTQPETIAVMSWMKSY 662
Query: 300 INQIKAYISMHSYSQHIVFPYS------YTRSKSKD---HEELSLVASE------AVRAI 344
+ A ++H S + +P+ T SKS D ++++L S+ R
Sbjct: 663 PFVLSA--NLHGGSLVVNYPFDDDEQGLATYSKSPDDAVFQQIALSYSKENSQMFQGRPC 720
Query: 345 EKTSKNTRYTHG-HGSETLYLAPGGGDDWIYDLGIKYSFTIEL 386
+ N + HG + Y PGG DW Y + TIEL
Sbjct: 721 KNMYPNEYFPHGITNGASWYNVPGGMQDWNYLQTNCFEVTIEL 763
Score = 33.9 bits (76), Expect = 0.29
Identities = 64/318 (20%), Positives = 117/318 (36%), Gaps = 62/318 (19%)
Query: 115 ASASYYEQYHSLNEIYSWI-EFITERHPDMLTKIHIGSSFEKYPLYVLKVS--------- 164
A+ +++Y+ E+ S + E P + IG S E PL+VL+++
Sbjct: 50 AAEGQFDRYYHEEELESALREAAAAGLPGLARLFSIGRSVEGRPLWVLRLTAGLGSLIPE 109
Query: 165 ---GKEQAAKNA----------IWIDCGIHAREWISPAFCLWFIGHITQFYGIIG-QYTN 210
G + A +A + + +H E +S ++ + Y +
Sbjct: 110 GDAGPDAAGPDAAGPLLPGRPQVKLVGNMHGDETVSRQVLIYLARELAAGYRRGDPRLVR 169
Query: 211 LLRLVDFYVMPVVNVDGYDYSWKKNRMWRKNRSFYAN--NHCIGTDLNRNFASKHWCEEG 268
LL D Y++P +N DG++ + + + + A+ ++ G DLNR+F + E
Sbjct: 170 LLNTTDVYLLPSLNPDGFERAREGDCGFGDGGPSGASGRDNSRGRDLNRSFPDQFSTGEP 229
Query: 269 ASSSSCSETYCGLYPESEPEVKAVASFLRRNINQIKAYISMHSYSQHIVFPYSY------ 322
+ + PEV+A+ ++RRN K +S + + +V Y +
Sbjct: 230 PAL------------DEVPEVRALIEWIRRN----KFVLSGNLHGGSVVASYPFDDSPEH 273
Query: 323 ----TRSKSKDHEELSLVASEAVRAIEKTSKNTRYTHGHGSETL----------YLAPGG 368
SK+ D E +A + G ET Y GG
Sbjct: 274 KATGIYSKTSDDEVFKYLAKAYASNHPIMKTGEPHCPGDEDETFKDGITNGAHWYDVEGG 333
Query: 369 GDDWIYDLGIKYSFTIEL 386
D+ Y + T+EL
Sbjct: 334 MQDYNYVWANCFEITLEL 351
>gi|9994201 carboxypeptidase X, member 1 precursor [Homo sapiens]
Length = 734
Score = 46.2 bits (108), Expect = 6e-05
Identities = 66/302 (21%), Positives = 129/302 (42%), Gaps = 44/302 (14%)
Query: 122 QYHSLNEIYSWIEFITERHPDMLTKIHIGSSFEKYPLYVLKVS---GKEQAAKNAIWIDC 178
Q+H+ + ++ + E+ P++ IG S++ LYV+++S G+ + + +
Sbjct: 298 QHHNYKAMRKLMKQVQEQCPNITRIYSIGKSYQGLKLYVMEMSDKPGEHELGEPEVRYVA 357
Query: 179 GIHAREWISPAFCLWFIGHIT-QFYGIIGQYTNLLRLVDFYVMPVVNVDGYDYSWKKNRM 237
G+H E + L + + +F + T LL + +++P +N DGY+ ++ +
Sbjct: 358 GMHGNEALGRELLLLLMQFLCHEFLRGNPRVTRLLSEMRIHLLPSMNPDGYEIAYHRGSE 417
Query: 238 ---WRKNRSFYANNHCIGTDLNRNFASKH---W--CEEGASSSSCSETYCGL-----YPE 284
W + R NN I DLN NFA + W ++G + L P
Sbjct: 418 LVGWAEGR---WNNQSI--DLNHNFADLNTPLWEAQDDGKVPHIVPNHHLPLPTYYTLPN 472
Query: 285 S--EPEVKAVASFLRRNINQIKAYISMHSYSQHIVFPYSYTRSKSKDHE----------- 331
+ PE +AV +++R + A ++H + +P+ TR+ E
Sbjct: 473 ATVAPETRAVIKWMKRIPFVLSA--NLHGGELVVSYPFDMTRTPWAARELTPTPDDAVFR 530
Query: 332 ELSLVASEAVRAIEKTSKNTRYT-----HGH--GSETLYLAPGGGDDWIYDLGIKYSFTI 384
LS V + + A++ TS+ ++ HG+ + PG +D+ Y + T+
Sbjct: 531 WLSTVYAGSNLAMQDTSRRPCHSQDFSVHGNIINGADWHTVPGSMNDFSYLHTNCFEVTV 590
Query: 385 EL 386
EL
Sbjct: 591 EL 592
>gi|223005864 carboxypeptidase X (M14 family), member 2 [Homo
sapiens]
Length = 756
Score = 42.4 bits (98), Expect = 8e-04
Identities = 32/147 (21%), Positives = 66/147 (44%), Gaps = 16/147 (10%)
Query: 122 QYHSLNEIYSWIEFITERHPDMLTKIHIGSSFEKYPLYVLKVS---GKEQAAKNAIWIDC 178
++H+ E+ ++ + E P++ +IG S + LY +++S G+ + +
Sbjct: 317 KHHNYKEMRQLMKVVNEMCPNITRIYNIGKSHQGLKLYAVEISDHPGEHEVGEPEFHYIA 376
Query: 179 GIHAREWISPAFCLWFIGHITQFYGIIGQYTNLLRLVD---FYVMPVVNVDGYDYSWKKN 235
G H E + L + + Q Y + + ++ LV+ +V+P +N DGY+ +++
Sbjct: 377 GAHGNEVLGRELLLLLVQFVCQEY--LARNARIVHLVEETRIHVLPSLNPDGYEKAYEGG 434
Query: 236 RM---WRKNRSFYANNHCIGTDLNRNF 259
W R + G D+N NF
Sbjct: 435 SELGGWSLGRWTHD-----GIDINNNF 456
>gi|4503009 carboxypeptidase E preproprotein [Homo sapiens]
Length = 476
Score = 37.7 bits (86), Expect = 0.020
Identities = 62/303 (20%), Positives = 116/303 (38%), Gaps = 48/303 (15%)
Query: 120 YEQYHSLNE--IYSWIEFITERHPDMLTKIH-IGSSFEKYPLYVLKVS---GKEQAAKNA 173
Y +Y L E + W++ +++I+ +G SFE L V+++S G + +
Sbjct: 53 YHRYPELREALVSVWLQCTA------ISRIYTVGRSFEGRELLVIELSDNPGVHEPGEPE 106
Query: 174 IWIDCGIHAREWISPAFCLWFIGHITQFYGIIGQ-YTNLLRLVDFYVMPVVNVDGYDYSW 232
+H E + ++ ++ Y + NL+ ++MP +N DG++ +
Sbjct: 107 FKYIGNMHGNEAVGRELLIFLAQYLCNEYQKGNETIVNLIHSTRIHIMPSLNPDGFEKA- 165
Query: 233 KKNRMWRKNRSFYANNHCIGTDLNRNFASKHWC-----EEGASSSSCSETYCGLYPES-- 285
++ F ++ G DLNRNF +EG ++ + + ++
Sbjct: 166 -ASQPGELKDWFVGRSNAQGIDLNRNFPDLDRIVYVNEKEGGPNNHLLKNMKKIVDQNTK 224
Query: 286 -EPEVKAVASFLRRNINQIKAYISMHSYSQHIVFPYSYTRSKSKDHEELSLVASEAV--- 341
PE KAV + I I +S + + +V Y Y ++S E S +A+
Sbjct: 225 LAPETKAVIHW----IMDIPFVLSANLHGGDLVANYPYDETRSGSAHEYSSSPDDAIFQS 280
Query: 342 --RA---------------IEKTSKNTRYTHG-HGSETLYLAPGGGDDWIYDLGIKYSFT 383
RA K ++ + G Y PGG D+ Y + T
Sbjct: 281 LARAYSSFNPAMSDPNRPPCRKNDDDSSFVDGTTNGGAWYSVPGGMQDFNYLSSNCFEIT 340
Query: 384 IEL 386
+EL
Sbjct: 341 VEL 343
>gi|4503011 carboxypeptidase N, polypeptide 1 precursor [Homo
sapiens]
Length = 458
Score = 37.0 bits (84), Expect = 0.034
Identities = 50/246 (20%), Positives = 94/246 (38%), Gaps = 17/246 (6%)
Query: 122 QYHSLNEIYSWIEFITERHPDMLTKIHIGSSFEKYPLYVLKVS---GKEQAAKNAIWIDC 178
++H +++ + + P + IG S E LYVL+ S G + + +
Sbjct: 24 RHHRYDDLVRTLYKVQNECPGITRVYSIGRSVEGRHLYVLEFSDHPGIHEPLEPEVKYVG 83
Query: 179 GIHAREWISPAFCLWFIGHITQFYGIIGQ-YTNLLRLVDFYVMPVVNVDGYDYSWKKNRM 237
+H E + L + + + Q L++ +++P +N DGY+ + +
Sbjct: 84 NMHGNEALGRELMLQLSEFLCEEFRNRNQRIVQLIQDTRIHILPSMNPDGYEVAAAQGP- 142
Query: 238 WRKNRSFYANNHCIGTDLNRNFASK----HWCEEGASSSSCSETYCGLYPESEPEVKAVA 293
K N+ G DLNRNF ++ E+ + + EPE +AV
Sbjct: 143 -NKPGYLVGRNNANGVDLNRNFPDLNTYIYYNEKYGGPNHHLPLPDNWKSQVEPETRAVI 201
Query: 294 SFLRRNINQIKAYISMHSYSQHIVFPYSYTRSKSKDHEELSLVASEAV---RAIEKTSKN 350
R ++ +S + + +V Y Y +S + AS + +K +K
Sbjct: 202 ----RWMHSFNFVLSANLHGGAVVANYPYDKSFEHRVRGVRRTASTPTPDDKLFQKLAKV 257
Query: 351 TRYTHG 356
Y HG
Sbjct: 258 YSYAHG 263
>gi|53832021 carboxypeptidase M precursor [Homo sapiens]
Length = 443
Score = 37.0 bits (84), Expect = 0.034
Identities = 33/140 (23%), Positives = 60/140 (42%), Gaps = 8/140 (5%)
Query: 123 YHSLNEIYSWIEFITERHPDMLTKIHIGSSFEKYPLYVLKVSGKEQAAKNAI---WIDCG 179
YH + ++++ + + + + IG S + L+VL V + + I
Sbjct: 22 YHRQEGMEAFLKTVAQNYSSVTHLHSIGKSVKGRNLWVLVVGRFPKEHRIGIPEFKYVAN 81
Query: 180 IHAREWISPAFCLWFIGHITQFYGIIGQYTNLLRLVDFYVMPVVNVDGYDYSWKKNRMWR 239
+H E + L I ++ G + TNL+ ++MP +N DG++ K + +
Sbjct: 82 MHGDETVGRELLLHLIDYLVTSDGKDPEITNLINSTRIHIMPSMNPDGFEAVKKPDCYYS 141
Query: 240 KNRSFYANNHCIGTDLNRNF 259
R Y N + DLNRNF
Sbjct: 142 IGRENY-NQY----DLNRNF 156
>gi|38327526 carboxypeptidase M precursor [Homo sapiens]
Length = 443
Score = 37.0 bits (84), Expect = 0.034
Identities = 33/140 (23%), Positives = 60/140 (42%), Gaps = 8/140 (5%)
Query: 123 YHSLNEIYSWIEFITERHPDMLTKIHIGSSFEKYPLYVLKVSGKEQAAKNAI---WIDCG 179
YH + ++++ + + + + IG S + L+VL V + + I
Sbjct: 22 YHRQEGMEAFLKTVAQNYSSVTHLHSIGKSVKGRNLWVLVVGRFPKEHRIGIPEFKYVAN 81
Query: 180 IHAREWISPAFCLWFIGHITQFYGIIGQYTNLLRLVDFYVMPVVNVDGYDYSWKKNRMWR 239
+H E + L I ++ G + TNL+ ++MP +N DG++ K + +
Sbjct: 82 MHGDETVGRELLLHLIDYLVTSDGKDPEITNLINSTRIHIMPSMNPDGFEAVKKPDCYYS 141
Query: 240 KNRSFYANNHCIGTDLNRNF 259
R Y N + DLNRNF
Sbjct: 142 IGRENY-NQY----DLNRNF 156
>gi|6631081 carboxypeptidase M precursor [Homo sapiens]
Length = 443
Score = 37.0 bits (84), Expect = 0.034
Identities = 33/140 (23%), Positives = 60/140 (42%), Gaps = 8/140 (5%)
Query: 123 YHSLNEIYSWIEFITERHPDMLTKIHIGSSFEKYPLYVLKVSGKEQAAKNAI---WIDCG 179
YH + ++++ + + + + IG S + L+VL V + + I
Sbjct: 22 YHRQEGMEAFLKTVAQNYSSVTHLHSIGKSVKGRNLWVLVVGRFPKEHRIGIPEFKYVAN 81
Query: 180 IHAREWISPAFCLWFIGHITQFYGIIGQYTNLLRLVDFYVMPVVNVDGYDYSWKKNRMWR 239
+H E + L I ++ G + TNL+ ++MP +N DG++ K + +
Sbjct: 82 MHGDETVGRELLLHLIDYLVTSDGKDPEITNLINSTRIHIMPSMNPDGFEAVKKPDCYYS 141
Query: 240 KNRSFYANNHCIGTDLNRNF 259
R Y N + DLNRNF
Sbjct: 142 IGRENY-NQY----DLNRNF 156
>gi|34740327 zinc finger protein 804A [Homo sapiens]
Length = 1209
Score = 33.1 bits (74), Expect = 0.49
Identities = 33/139 (23%), Positives = 57/139 (41%), Gaps = 24/139 (17%)
Query: 224 NVDGYDYSWKKNRMWRKNRSFYANNHCIGTDLNRNFASKHWCEEGASSSSCS-------- 275
+++ YD++ K+ K R F RN ASK +E +
Sbjct: 75 HINSYDHAHKQRLKELKQREFA-----------RNVASKSRKDERKQEKALQRLHKLAEL 123
Query: 276 --ETYCGLYPESEPEVKAVASFLRRNINQIKAYISMHSYSQHIVFPYSYTRSKSKDHEEL 333
ET C P S P K+ +R N N+I + + S + F Y+ S+ ++ ++
Sbjct: 124 RKETVCA--PGSGPMFKSTTVTVRENCNEISQRVVVDSVNNQQDFKYTLIHSE-ENTKDA 180
Query: 334 SLVASEAVRAIEKTSKNTR 352
+ VA + A T+KN +
Sbjct: 181 TTVAEDPESANNYTAKNNQ 199
>gi|94400919 WD repeat domain 90 [Homo sapiens]
Length = 1748
Score = 30.8 bits (68), Expect = 2.4
Identities = 24/102 (23%), Positives = 43/102 (42%), Gaps = 9/102 (8%)
Query: 225 VDGYDYSWKKNRMWRKNRSFYA---NNHCIGTDLNRNFASKHWCEEGASSSSCSETYCGL 281
V GY + + N +WR + F+A + DL+ A +HW A S+ + ++
Sbjct: 1113 VVGYSGNGRANMVWRPDTGFFAYTCGRLVVVEDLHSG-AQQHWSGHSAEISTLALSHSAQ 1171
Query: 282 YPESEPEVKAVASFLRRNINQIKAYISMHSYSQHIVFPYSYT 323
S + + QI+ + QH++FP+S T
Sbjct: 1172 VLASASGRSSTTAHC-----QIRVWDVSGGLCQHLIFPHSTT 1208
>gi|10835079 gap junction protein, beta 5, 31.1kDa [Homo sapiens]
Length = 273
Score = 30.0 bits (66), Expect = 4.1
Identities = 20/76 (26%), Positives = 31/76 (40%), Gaps = 3/76 (3%)
Query: 334 SLVASEAVRAIEKTSKNTRYTHGHGSETLYLAPG---GGDDWIYDLGIKYSFTIELRDTG 390
SL+ V E K R HG S LYL PG GG W Y + + ++++
Sbjct: 88 SLLVVMHVAYREVQEKRHREAHGENSGRLYLNPGKKRGGLWWTYVCSLVFKASVDIAFLY 147
Query: 391 TYGFLLPERYIKPTCR 406
+ P+ + P +
Sbjct: 148 VFHSFYPKYILPPVVK 163
>gi|4759248 tryptophan hydroxylase 1 [Homo sapiens]
Length = 444
Score = 29.6 bits (65), Expect = 5.4
Identities = 16/69 (23%), Positives = 34/69 (49%), Gaps = 5/69 (7%)
Query: 254 DLNRNFASKHWCEEGASSSSCSETYCGLYPESEPEVKAVASFLRR----NINQIKAYISM 309
+LN+ + + H C E + YCG ++ P+++ V++FL+ +I + Y+S
Sbjct: 180 ELNKLYPT-HACREYLKNLPLLSKYCGYREDNIPQLEDVSNFLKERTGFSIRPVAGYLSP 238
Query: 310 HSYSQHIVF 318
+ + F
Sbjct: 239 RDFLSGLAF 247
>gi|89191868 von Willebrand factor preproprotein [Homo sapiens]
Length = 2813
Score = 28.9 bits (63), Expect = 9.2
Identities = 19/60 (31%), Positives = 27/60 (45%), Gaps = 4/60 (6%)
Query: 347 TSKNTRYTHGHGSETLYLAPGGGDDWIYDL-GIKYSFTIELRDTGTYGFLLPERYIKPTC 405
T + R + + S+ LYL G Y L G Y F + +G + LL +RY TC
Sbjct: 103 TQGDQRVSMPYASKGLYLETEAG---YYKLSGEAYGFVARIDGSGNFQVLLSDRYFNKTC 159
>gi|38348244 hypothetical protein LOC200844 [Homo sapiens]
Length = 563
Score = 28.9 bits (63), Expect = 9.2
Identities = 37/154 (24%), Positives = 60/154 (38%), Gaps = 32/154 (20%)
Query: 247 NNHCIGTDLNRNFASKH--WCEEGASSSSCSETYCG--LYPESEPEVKAVASFLRRNINQ 302
NN I ++ R+ SK+ C+ + T L PESE + + NI+Q
Sbjct: 152 NNMKISSETVRSVGSKNNRSCQPSTVEKCVNGTEMSALLIPESEEQGN------KENIHQ 205
Query: 303 IKAYISMHSYSQHIVFPYS---------------YTRSKSKDHEELSLVASEAVRAIE-K 346
IK + +H+ + HI+ P+ +S S++ E +S IE K
Sbjct: 206 IKQTVPIHAANLHIMHPHPPQEPSADKNNNRRRLRLKSTSRERTETPSGSSSGNNRIEDK 265
Query: 347 TSKNTRYTHGHGSETLY------LAPGGGDDWIY 374
S G+E L +P D+WI+
Sbjct: 266 ASTILTTVSQQGAELLNSGTLGPQSPDQSDEWIF 299
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.321 0.135 0.419
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 15,692,797
Number of Sequences: 37866
Number of extensions: 655802
Number of successful extensions: 1561
Number of sequences better than 10.0: 27
Number of HSP's better than 10.0 without gapping: 14
Number of HSP's successfully gapped in prelim test: 13
Number of HSP's that attempted gapping in prelim test: 1498
Number of HSP's gapped (non-prelim): 32
length of query: 423
length of database: 18,247,518
effective HSP length: 105
effective length of query: 318
effective length of database: 14,271,588
effective search space: 4538364984
effective search space used: 4538364984
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.