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Search of human proteins with 126273559
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|126273559 plasma carboxypeptidase B2 isoform b [Homo
sapiens]
(360 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|126273559 plasma carboxypeptidase B2 isoform b [Homo sapiens] 739 0.0
gi|126273569 plasma carboxypeptidase B2 isoform a preproprotein ... 692 0.0
gi|54607080 pancreatic carboxypeptidase B1 preproprotein [Homo s... 240 2e-63
gi|221316749 carboxypeptidase A3 precursor [Homo sapiens] 230 2e-60
gi|188536067 carboxypeptidase A6 isoform 1 precursor [Homo sapiens] 226 2e-59
gi|27436871 carboxypeptidase O [Homo sapiens] 212 5e-55
gi|188536053 carboxypeptidase A5 isoform 1 [Homo sapiens] 190 2e-48
gi|188536051 carboxypeptidase A5 isoform 1 [Homo sapiens] 190 2e-48
gi|217416390 carboxypeptidase A2 (pancreatic) precursor [Homo sa... 187 2e-47
gi|4502997 carboxypeptidase A1 precursor [Homo sapiens] 179 3e-45
gi|61743916 carboxypeptidase A4 preproprotein [Homo sapiens] 177 2e-44
gi|188536055 carboxypeptidase A5 isoform 2 [Homo sapiens] 159 4e-39
gi|188536069 carboxypeptidase A6 isoform 2 [Homo sapiens] 84 3e-16
gi|7661910 tetratricopeptide repeat domain 35 [Homo sapiens] 35 0.14
gi|219842346 NADPH oxidase 4 isoform b [Homo sapiens] 30 2.6
gi|219842348 NADPH oxidase 4 isoform c [Homo sapiens] 30 2.6
gi|8393843 NADPH oxidase 4 isoform a [Homo sapiens] 30 2.6
gi|34740327 zinc finger protein 804A [Homo sapiens] 30 3.4
gi|4759248 tryptophan hydroxylase 1 [Homo sapiens] 30 4.4
gi|22202611 carboxypeptidase D precursor [Homo sapiens] 29 7.5
gi|9994201 carboxypeptidase X, member 1 precursor [Homo sapiens] 29 7.5
gi|38348244 hypothetical protein LOC200844 [Homo sapiens] 29 7.5
gi|12707562 period 2 [Homo sapiens] 28 9.8
>gi|126273559 plasma carboxypeptidase B2 isoform b [Homo sapiens]
Length = 360
Score = 739 bits (1908), Expect = 0.0
Identities = 360/360 (100%), Positives = 360/360 (100%)
Query: 1 MKLCSLAVLVPIVLFCEQHVFAFQSGQVLAALPRTSRQVQVLQNLTTTYEIVLWQPVTAD 60
MKLCSLAVLVPIVLFCEQHVFAFQSGQVLAALPRTSRQVQVLQNLTTTYEIVLWQPVTAD
Sbjct: 1 MKLCSLAVLVPIVLFCEQHVFAFQSGQVLAALPRTSRQVQVLQNLTTTYEIVLWQPVTAD 60
Query: 61 LIVKKKQVHFFVNASDVDNVKAHLNVSGIPCSVLLADVEDLIQQQISNDTVSPRASASYY 120
LIVKKKQVHFFVNASDVDNVKAHLNVSGIPCSVLLADVEDLIQQQISNDTVSPRASASYY
Sbjct: 61 LIVKKKQVHFFVNASDVDNVKAHLNVSGIPCSVLLADVEDLIQQQISNDTVSPRASASYY 120
Query: 121 EQYHSLNEIYSWIEFITERHPDMLTKIHIGSSFEKYPLYVLKVSGKEQAAKNAIWIDCGI 180
EQYHSLNEIYSWIEFITERHPDMLTKIHIGSSFEKYPLYVLKVSGKEQAAKNAIWIDCGI
Sbjct: 121 EQYHSLNEIYSWIEFITERHPDMLTKIHIGSSFEKYPLYVLKVSGKEQAAKNAIWIDCGI 180
Query: 181 HAREWISPAFCLWFIGHNRMWRKNRSFYANNHCIGTDLNRNFASKHWCEEGASSSSCSET 240
HAREWISPAFCLWFIGHNRMWRKNRSFYANNHCIGTDLNRNFASKHWCEEGASSSSCSET
Sbjct: 181 HAREWISPAFCLWFIGHNRMWRKNRSFYANNHCIGTDLNRNFASKHWCEEGASSSSCSET 240
Query: 241 YCGLYPESEPEVKAVASFLRRNINQIKAYISMHSYSQHIVFPYSYTRSKSKDHEELSLVA 300
YCGLYPESEPEVKAVASFLRRNINQIKAYISMHSYSQHIVFPYSYTRSKSKDHEELSLVA
Sbjct: 241 YCGLYPESEPEVKAVASFLRRNINQIKAYISMHSYSQHIVFPYSYTRSKSKDHEELSLVA 300
Query: 301 SEAVRAIEKTSKNTRYTHGHGSETLYLAPGGGDDWIYDLGIKYSVTSNPPVEKLLPLSLK 360
SEAVRAIEKTSKNTRYTHGHGSETLYLAPGGGDDWIYDLGIKYSVTSNPPVEKLLPLSLK
Sbjct: 301 SEAVRAIEKTSKNTRYTHGHGSETLYLAPGGGDDWIYDLGIKYSVTSNPPVEKLLPLSLK 360
>gi|126273569 plasma carboxypeptidase B2 isoform a preproprotein
[Homo sapiens]
Length = 423
Score = 692 bits (1785), Expect = 0.0
Identities = 345/383 (90%), Positives = 345/383 (90%), Gaps = 37/383 (9%)
Query: 1 MKLCSLAVLVPIVLFCEQHVFAFQSGQVLAALPRTSRQVQVLQNLTTTYEIVLWQPVTAD 60
MKLCSLAVLVPIVLFCEQHVFAFQSGQVLAALPRTSRQVQVLQNLTTTYEIVLWQPVTAD
Sbjct: 1 MKLCSLAVLVPIVLFCEQHVFAFQSGQVLAALPRTSRQVQVLQNLTTTYEIVLWQPVTAD 60
Query: 61 LIVKKKQVHFFVNASDVDNVKAHLNVSGIPCSVLLADVEDLIQQQISNDTVSPRASASYY 120
LIVKKKQVHFFVNASDVDNVKAHLNVSGIPCSVLLADVEDLIQQQISNDTVSPRASASYY
Sbjct: 61 LIVKKKQVHFFVNASDVDNVKAHLNVSGIPCSVLLADVEDLIQQQISNDTVSPRASASYY 120
Query: 121 EQYHSLNEIYSWIEFITERHPDMLTKIHIGSSFEKYPLYVLKVSGKEQAAKNAIWIDCGI 180
EQYHSLNEIYSWIEFITERHPDMLTKIHIGSSFEKYPLYVLKVSGKEQAAKNAIWIDCGI
Sbjct: 121 EQYHSLNEIYSWIEFITERHPDMLTKIHIGSSFEKYPLYVLKVSGKEQAAKNAIWIDCGI 180
Query: 181 HAREWISPAFCLWFIGH-------------------------------------NRMWRK 203
HAREWISPAFCLWFIGH NRMWRK
Sbjct: 181 HAREWISPAFCLWFIGHITQFYGIIGQYTNLLRLVDFYVMPVVNVDGYDYSWKKNRMWRK 240
Query: 204 NRSFYANNHCIGTDLNRNFASKHWCEEGASSSSCSETYCGLYPESEPEVKAVASFLRRNI 263
NRSFYANNHCIGTDLNRNFASKHWCEEGASSSSCSETYCGLYPESEPEVKAVASFLRRNI
Sbjct: 241 NRSFYANNHCIGTDLNRNFASKHWCEEGASSSSCSETYCGLYPESEPEVKAVASFLRRNI 300
Query: 264 NQIKAYISMHSYSQHIVFPYSYTRSKSKDHEELSLVASEAVRAIEKTSKNTRYTHGHGSE 323
NQIKAYISMHSYSQHIVFPYSYTRSKSKDHEELSLVASEAVRAIEKTSKNTRYTHGHGSE
Sbjct: 301 NQIKAYISMHSYSQHIVFPYSYTRSKSKDHEELSLVASEAVRAIEKTSKNTRYTHGHGSE 360
Query: 324 TLYLAPGGGDDWIYDLGIKYSVT 346
TLYLAPGGGDDWIYDLGIKYS T
Sbjct: 361 TLYLAPGGGDDWIYDLGIKYSFT 383
>gi|54607080 pancreatic carboxypeptidase B1 preproprotein [Homo
sapiens]
Length = 417
Score = 240 bits (612), Expect = 2e-63
Identities = 134/382 (35%), Positives = 205/382 (53%), Gaps = 44/382 (11%)
Query: 3 LCSLAVLVPIVLFCEQHVFA-FQSGQVLAALPRTSRQVQVLQNLTTTYEIVLWQPVTADL 61
+ +L VLV + L H F+ +V + +++ L +T +I W+P +
Sbjct: 1 MLALLVLVTVALASAHHGGEHFEGEKVFRVNVEDENHINIIRELASTTQIDFWKPDSVTQ 60
Query: 62 IVKKKQVHFFVNASDVDNVKAHLNVSGIPCSVLLADVEDLIQQQISNDTVSPRASASYYE 121
I V F V A D V+ L + + VL++++ ++++ Q + RA+ YE
Sbjct: 61 IKPHSTVDFRVKAEDTVTVENVLKQNELQYKVLISNLRNVVEAQFDSRV---RATGHSYE 117
Query: 122 QYHSLNEIYSWIEFITERHPDMLTKIHIGSSFEKYPLYVLKVSGKEQAAKNAIWIDCGIH 181
+Y+ I +W + + +P ++++ IG++FE +Y+LKV GK K AI++DCG H
Sbjct: 118 KYNKWETIEAWTQQVATENPALISRSVIGTTFEGRAIYLLKV-GKAGQNKPAIFMDCGFH 176
Query: 182 AREWISPAFCLWFIGH-------------------------------------NRMWRKN 204
AREWISPAFC WF+ +R WRK
Sbjct: 177 AREWISPAFCQWFVREAVRTYGREIQVTELLDKLDFYVLPVLNIDGYIYTWTKSRFWRKT 236
Query: 205 RSFYANNHCIGTDLNRNFASKHWCEEGASSSSCSETYCGLYPESEPEVKAVASFLRRNIN 264
RS + + CIGTD NRNF + WCE GAS + C ETYCG ESE E KA+A F+R ++
Sbjct: 237 RSTHTGSSCIGTDPNRNFDAG-WCEIGASRNPCDETYCGPAAESEKETKALADFIRNKLS 295
Query: 265 QIKAYISMHSYSQHIVFPYSYTRSKSKDHEELSLVASEAVRAIEKTSKNTRYTHGHGSET 324
IKAY+++HSYSQ +++PYSY +++ EL+ +A V+ + + T+YT+G G+ T
Sbjct: 296 SIKAYLTIHSYSQMMIYPYSYAYKLGENNAELNALAKATVKEL-ASLHGTKYTYGPGATT 354
Query: 325 LYLAPGGGDDWIYDLGIKYSVT 346
+Y A GG DDW YD GI+YS T
Sbjct: 355 IYPAAGGSDDWAYDQGIRYSFT 376
>gi|221316749 carboxypeptidase A3 precursor [Homo sapiens]
Length = 417
Score = 230 bits (586), Expect = 2e-60
Identities = 130/380 (34%), Positives = 202/380 (53%), Gaps = 47/380 (12%)
Query: 6 LAVLVPIVLFCEQHVFA---FQSGQVLAALPRTSRQVQVLQNLTTTYEIVLWQPVTADLI 62
+ +++P+ L A F +V P+ +Q ++++L T E+ W P +
Sbjct: 1 MRLILPVGLIATTLAIAPVRFDREKVFRVKPQDEKQADIIKDLAKTNELDFWYPGATHHV 60
Query: 63 VKKKQVHFFVNASDVDNVKAHLNVSGIPCSVLLADVEDLIQQQIS-NDTVSPRASASYYE 121
V F V+ + +++ L+ + + +L+ D+++ I++Q + + R S Y
Sbjct: 61 AANMMVDFRVSEKESQAIQSALDQNKMHYEILIHDLQEEIEKQFDVKEDIPGRHS---YA 117
Query: 122 QYHSLNEIYSWIEFITERHPDMLTKIHIGSSFEKYPLYVLKVSGKEQAAKNAIWIDCGIH 181
+Y++ +I +W E + +++P+M+++I IGS+ E PLYVLK+ K + K AI+ DCGIH
Sbjct: 118 KYNNWEKIVAWTEKMMDKYPEMVSRIKIGSTVEDNPLYVLKIGEKNERRK-AIFTDCGIH 176
Query: 182 AREWISPAFCLWFI-------------------------------------GHNRMWRKN 204
AREW+SPAFC WF+ NRMWRKN
Sbjct: 177 AREWVSPAFCQWFVYQATKTYGRNKIMTKLLDRMNFYILPVFNVDGYIWSWTKNRMWRKN 236
Query: 205 RSFYANNHCIGTDLNRNFASKHWCEEGASSSSCSETYCGLYPESEPEVKAVASFLRRNIN 264
RS N+ CIGTDLNRNF + W ++ C++ Y G PESE E KAV +F+R ++N
Sbjct: 237 RSKNQNSKCIGTDLNRNF-NASWNSIPNTNDPCADNYRGSAPESEKETKAVTNFIRSHLN 295
Query: 265 QIKAYISMHSYSQHIVFPYSYTRSKSKDHEELSLVASEAVRAIEKTSKNTRYTHGHGSET 324
+IK YI+ HSYSQ ++FPY YT +HE+L+ VA + T TRY +G T
Sbjct: 296 EIKVYITFHSYSQMLLFPYGYTSKLPPNHEDLAKVAKIGTDVL-STRYETRYIYGPIEST 354
Query: 325 LYLAPGGGDDWIYDLGIKYS 344
+Y G DW YDLGIK++
Sbjct: 355 IYPISGSSLDWAYDLGIKHT 374
>gi|188536067 carboxypeptidase A6 isoform 1 precursor [Homo sapiens]
Length = 437
Score = 226 bits (577), Expect = 2e-59
Identities = 124/361 (34%), Positives = 188/361 (52%), Gaps = 42/361 (11%)
Query: 23 FQSGQVLAALPRTSRQVQVLQNLTTTYEIVLWQPVTADLIVKKKQVHFFVNASDVDNVKA 82
+ +V+ +P+T + L+ ++ ++ LWQP + + + + + + A
Sbjct: 37 YAGDKVIRFIPKTEEEAYALKKISYQLKVDLWQPSSISYVSEGTVTDVHIPQNGSRALLA 96
Query: 83 HLNVSGIPCSVLLADVEDLIQQQISNDTVSPRASAS--YYEQYHSLNEIYSWIEFITERH 140
L + I VL+ D++ +++ S T R S S YE YHSL EI +W+ + + H
Sbjct: 97 FLQEANIQYKVLIEDLQKTLEKGSSLHTQRNRRSLSGYNYEVYHSLEEIQNWMHHLNKTH 156
Query: 141 PDMLTKIHIGSSFEKYPLYVLKVSGKEQAAKNAIWIDCGIHAREWISPAFCLWFIG---- 196
++ IG S+E L++LK+ G+ K A+WIDCGIHAREWI PAFC WF+
Sbjct: 157 SGLIHMFSIGRSYEGRSLFILKL-GRRSRLKRAVWIDCGIHAREWIGPAFCQWFVKEALL 215
Query: 197 ---------------------------------HNRMWRKNRSFYANNHCIGTDLNRNFA 223
++R WRK RS + C G D NRN+
Sbjct: 216 TYKSDPAMRKMLNHLYFYIMPVFNVDGYHFSWTNDRFWRKTRSRNSRFRCRGVDANRNWK 275
Query: 224 SKHWCEEGASSSSCSETYCGLYPESEPEVKAVASFLRRNINQIKAYISMHSYSQHIVFPY 283
K WC+EGAS C +TYCG +PESEPEVKAVA+FLR++ I+AY+S H+Y+Q +++PY
Sbjct: 276 VK-WCDEGASMHPCDDTYCGPFPESEPEVKAVANFLRKHRKHIRAYLSFHAYAQMLLYPY 334
Query: 284 SYTRSKSKDHEELSLVASEAVRAIEKTSKNTRYTHGHGSETLYLAPGGGDDWIYDLGIKY 343
SY + + + A +AV A++ RY +G S TLY++ G DW Y GI Y
Sbjct: 335 SYKYATIPNFRCVESAAYKAVNALQSV-YGVRYRYGPASTTLYVSSGSSMDWAYKNGIPY 393
Query: 344 S 344
+
Sbjct: 394 A 394
>gi|27436871 carboxypeptidase O [Homo sapiens]
Length = 374
Score = 212 bits (539), Expect = 5e-55
Identities = 109/282 (38%), Positives = 158/282 (56%), Gaps = 40/282 (14%)
Query: 103 QQQISNDTVSPRASASY-YEQYHSLNEIYSWIEFITERHPDMLTKIHIGSSFEKYPLYVL 161
+Q+I + +VSP + +Y Y YH + EIY W+ I+E++ +++T+ +G ++E +P+Y L
Sbjct: 29 RQEIVDKSVSPWSLETYSYNIYHPMGEIYEWMREISEKYKEVVTQHFLGVTYETHPMYYL 88
Query: 162 KVSGKEQAAKNAIWIDCGIHAREWISPAFCLWFIGH------------------------ 197
K+S K IW+DCGIHAREWI+PAFC WF+
Sbjct: 89 KISQPSGNPKKIIWMDCGIHAREWIAPAFCQWFVKEILQNHKDNSSIRKLLRNLDFYVLP 148
Query: 198 -------------NRMWRKNRSFYANNHCIGTDLNRNFASKHWCEEGASSSSCSETYCGL 244
+R+WRK+RS + N C GTDLNRNF + WC GAS + +T+CG
Sbjct: 149 VLNIDGYIYTWTTDRLWRKSRSPHNNGTCFGTDLNRNFNAS-WCSIGASRNCQDQTFCGT 207
Query: 245 YPESEPEVKAVASFLRRNINQIKAYISMHSYSQHIVFPYSYTRSKSKDHEELSLVASEAV 304
P SEPE KAVASF+ + I +++MHSY Q I+ PY YT++KS +H E+ V +A
Sbjct: 208 GPVSEPETKAVASFIESKKDDILCFLTMHSYGQLILTPYGYTKNKSSNHPEMIQVGQKAA 267
Query: 305 RAIEKTSKNTRYTHGHGSETLYLAPGGGDDWIYDLGIKYSVT 346
A+ K T Y G ++ LY + G DW D+GI +S T
Sbjct: 268 NAL-KAKYGTNYRVGSSADILYASSGSSRDWARDIGIPFSYT 308
>gi|188536053 carboxypeptidase A5 isoform 1 [Homo sapiens]
Length = 436
Score = 190 bits (482), Expect = 2e-48
Identities = 128/365 (35%), Positives = 185/365 (50%), Gaps = 51/365 (13%)
Query: 23 FQSGQVLAALPRTSRQVQVLQNLT--TTYEIVLWQPVTADLIVKKKQVHFFVNASDVDNV 80
F QVL L + +Q+ +L +L ++ W+ + +V F S++ ++
Sbjct: 37 FTGDQVLRVLAKDEKQLSLLGDLEGLKPQKVDFWRGPARPSLPVDMRVPF----SELKDI 92
Query: 81 KAHLNVSGIPCSVLLADVEDLIQQQISNDTVSPRASASY----YEQYHSLNEIYSWIEFI 136
KA+L G+ S+++ D++ L+ ++ S R S Y YH+L EIYSWI+
Sbjct: 93 KAYLESHGLAYSIMIKDIQVLLDEERQAMAKSRRLERSTNSFSYSSYHTLEEIYSWIDNF 152
Query: 137 TERHPDMLTKIHIGSSFEKYPLYVLKVSGKEQAAKNAIWIDCGIHAREWISPAFCLW--- 193
H D+++KI IG+SFE + VLK S + AIWID GIH+REWI+ A +W
Sbjct: 153 VMEHSDIVSKIQIGNSFENQSILVLKFS-TGGSRHPAIWIDTGIHSREWITHATGIWTAN 211
Query: 194 ---------------------FI-------------GHNRMWRKNRSFYANNHCIGTDLN 219
FI NR+WRKN+S CIG DLN
Sbjct: 212 KIVSDYGKDRVLTDILNAMDIFIELVTNPDGFAFTHSMNRLWRKNKSIRPGIFCIGVDLN 271
Query: 220 RNFASKHWCEEGASSSSCSETYCGLYPESEPEVKAVASFLRRNINQIKAYISMHSYSQHI 279
RN+ S + G++S+ CSETY G P+SEPEV A+ +F+ + N KA IS+HSYSQ +
Sbjct: 272 RNWKSG-FGGNGSNSNPCSETYHGPSPQSEPEVAAIVNFITAHGN-FKALISIHSYSQML 329
Query: 280 VFPYSYTRSKSKDHEELSLVASEAVRAIEKTSKNTRYTHGHGSETLYLAPGGGDDWIYDL 339
++PY + EL +A +AV A+ K Y G S TLY+A G DW YD
Sbjct: 330 MYPYGRLLEPVSNQRELYDLAKDAVEALYKV-HGIEYIFGSISTTLYVASGITVDWAYDS 388
Query: 340 GIKYS 344
GIKY+
Sbjct: 389 GIKYA 393
>gi|188536051 carboxypeptidase A5 isoform 1 [Homo sapiens]
Length = 436
Score = 190 bits (482), Expect = 2e-48
Identities = 128/365 (35%), Positives = 185/365 (50%), Gaps = 51/365 (13%)
Query: 23 FQSGQVLAALPRTSRQVQVLQNLT--TTYEIVLWQPVTADLIVKKKQVHFFVNASDVDNV 80
F QVL L + +Q+ +L +L ++ W+ + +V F S++ ++
Sbjct: 37 FTGDQVLRVLAKDEKQLSLLGDLEGLKPQKVDFWRGPARPSLPVDMRVPF----SELKDI 92
Query: 81 KAHLNVSGIPCSVLLADVEDLIQQQISNDTVSPRASASY----YEQYHSLNEIYSWIEFI 136
KA+L G+ S+++ D++ L+ ++ S R S Y YH+L EIYSWI+
Sbjct: 93 KAYLESHGLAYSIMIKDIQVLLDEERQAMAKSRRLERSTNSFSYSSYHTLEEIYSWIDNF 152
Query: 137 TERHPDMLTKIHIGSSFEKYPLYVLKVSGKEQAAKNAIWIDCGIHAREWISPAFCLW--- 193
H D+++KI IG+SFE + VLK S + AIWID GIH+REWI+ A +W
Sbjct: 153 VMEHSDIVSKIQIGNSFENQSILVLKFS-TGGSRHPAIWIDTGIHSREWITHATGIWTAN 211
Query: 194 ---------------------FI-------------GHNRMWRKNRSFYANNHCIGTDLN 219
FI NR+WRKN+S CIG DLN
Sbjct: 212 KIVSDYGKDRVLTDILNAMDIFIELVTNPDGFAFTHSMNRLWRKNKSIRPGIFCIGVDLN 271
Query: 220 RNFASKHWCEEGASSSSCSETYCGLYPESEPEVKAVASFLRRNINQIKAYISMHSYSQHI 279
RN+ S + G++S+ CSETY G P+SEPEV A+ +F+ + N KA IS+HSYSQ +
Sbjct: 272 RNWKSG-FGGNGSNSNPCSETYHGPSPQSEPEVAAIVNFITAHGN-FKALISIHSYSQML 329
Query: 280 VFPYSYTRSKSKDHEELSLVASEAVRAIEKTSKNTRYTHGHGSETLYLAPGGGDDWIYDL 339
++PY + EL +A +AV A+ K Y G S TLY+A G DW YD
Sbjct: 330 MYPYGRLLEPVSNQRELYDLAKDAVEALYKV-HGIEYIFGSISTTLYVASGITVDWAYDS 388
Query: 340 GIKYS 344
GIKY+
Sbjct: 389 GIKYA 393
>gi|217416390 carboxypeptidase A2 (pancreatic) precursor [Homo
sapiens]
Length = 419
Score = 187 bits (474), Expect = 2e-47
Identities = 123/364 (33%), Positives = 183/364 (50%), Gaps = 51/364 (14%)
Query: 23 FQSGQVLAALPRTSRQVQVLQNLTTTYEIVL--WQPVTADLIVKKKQVHFFVNASDVDNV 80
F QVL +P Q++ L L + L W+ T + H V +V V
Sbjct: 22 FVGDQVLEIVPSNEEQIKNLLQLEAQEHLQLDFWKSPTTP----GETAHVRVPFVNVQAV 77
Query: 81 KAHLNVSGIPCSVLLADVEDLIQQQISNDTVSPRASAS---YYEQYHSLNEIYSWIEFIT 137
K L GI S+++ DV+ L+ ++ + R S + YH+L EI ++ +
Sbjct: 78 KVFLESQGIAYSIMIEDVQVLLDKENEEMLFNRRRERSGNFNFGAYHTLEEISQEMDNLV 137
Query: 138 ERHPDMLTKIHIGSSFEKYPLYVLKVSGKEQAAKNAIWIDCGIHAREWISPAFCLWFIGH 197
HP +++K++IGSSFE P+ VLK S K AIW+D GIHAREW++ A LW
Sbjct: 138 AEHPGLVSKVNIGSSFENRPMNVLKFS--TGGDKPAIWLDAGIHAREWVTQATALWTANK 195
Query: 198 -------------------------------------NRMWRKNRSFYANNHCIGTDLNR 220
NRMWRK RS + + C+G D NR
Sbjct: 196 IVSDYGKDPSITSILDALDIFLLPVTNPDGYVFSQTKNRMWRKTRSKVSGSLCVGVDPNR 255
Query: 221 NFASKHWCEEGASSSSCSETYCGLYPESEPEVKAVASFLRRNINQIKAYISMHSYSQHIV 280
N+ + + GASS+ CS++Y G SE EVK++ F++ + ++KA+I++HSYSQ ++
Sbjct: 256 NWDAG-FGGPGASSNPCSDSYHGPSANSEVEVKSIVDFIKSH-GKVKAFITLHSYSQLLM 313
Query: 281 FPYSYTRSKSKDHEELSLVASEAVRAIEKTSKNTRYTHGHGSETLYLAPGGGDDWIYDLG 340
FPY Y +K D +ELS VA +A +++ ++ T+Y G +Y A GG DW YD G
Sbjct: 314 FPYGYKCTKLDDFDELSEVAQKAAQSL-RSLHGTKYKVGPICSVIYQASGGSIDWSYDYG 372
Query: 341 IKYS 344
IKYS
Sbjct: 373 IKYS 376
>gi|4502997 carboxypeptidase A1 precursor [Homo sapiens]
Length = 419
Score = 179 bits (454), Expect = 3e-45
Identities = 110/311 (35%), Positives = 165/311 (53%), Gaps = 45/311 (14%)
Query: 77 VDNVKAHLNVSGIPCSVLLADVEDLI---QQQISNDTVSPRASASY-YEQYHSLNEIYSW 132
+ VK L GI ++ DV+ L+ Q+Q+ R++ ++ Y YH+L EIY +
Sbjct: 72 IQAVKIFLESHGISYETMIEDVQSLLDEEQEQMFAFRSRARSTDTFNYATYHTLEEIYDF 131
Query: 133 IEFITERHPDMLTKIHIGSSFEKYPLYVLKVSGKEQAAKNAIWIDCGIHAREWISPAFCL 192
++ + +P +++KI IG+++E P+YVLK S + + AIWID GIH+REW++ A +
Sbjct: 132 LDLLVAENPHLVSKIQIGNTYEGRPIYVLKFS-TGGSKRPAIWIDTGIHSREWVTQASGV 190
Query: 193 WFI-------------------------------------GHNRMWRKNRSFYANNHCIG 215
WF NRMWRK RS A + CIG
Sbjct: 191 WFAKKITQDYGQDAAFTAILDTLDIFLEIVTNPDGFAFTHSTNRMWRKTRSHTAGSLCIG 250
Query: 216 TDLNRNFASKHWCEEGASSSSCSETYCGLYPESEPEVKAVASFLRRNINQIKAYISMHSY 275
D NRN+ + GASS+ CSETY G + SE EVK++ F++ + N IKA+IS+HSY
Sbjct: 251 VDPNRNWDAGFGLS-GASSNPCSETYHGKFANSEVEVKSIVDFVKDHGN-IKAFISIHSY 308
Query: 276 SQHIVFPYSYTRSKSKDHEELSLVASEAVRAIEKTSKNTRYTHGHGSETLYLAPGGGDDW 335
SQ +++PY Y D +EL ++ AV A+ + T++ +G + +Y A G DW
Sbjct: 309 SQLLMYPYGYKTEPVPDQDELDQLSKAAVTAL-ASLYGTKFNYGSIIKAIYQASGSTIDW 367
Query: 336 IYDLGIKYSVT 346
Y GIKYS T
Sbjct: 368 TYSQGIKYSFT 378
>gi|61743916 carboxypeptidase A4 preproprotein [Homo sapiens]
Length = 421
Score = 177 bits (448), Expect = 2e-44
Identities = 117/367 (31%), Positives = 179/367 (48%), Gaps = 50/367 (13%)
Query: 23 FQSGQVLAALPRTSRQVQVLQNLTTTYEIVL--WQPVTADLIVKKKQVHFFVNASDVDNV 80
F QVL R ++ L L + + L W+ ++ + V V + +
Sbjct: 21 FFGDQVLRINVRNGDEISKLSQLVNSNNLKLNFWKSPSSF----NRPVDVLVPSVSLQAF 76
Query: 81 KAHLNVSGIPCSVLLADVEDLIQQQ---ISNDTVSPRASASY-YEQYHSLNEIYSWIEFI 136
K+ L G+ +V + D++ L+ + + ++ R+S ++ Y YHSL IY ++ I
Sbjct: 77 KSFLRSQGLEYAVTIEDLQALLDNEDDEMQHNEGQERSSNNFNYGAYHSLEAIYHEMDNI 136
Query: 137 TERHPDMLTKIHIGSSFEKYPLYVLKVSGKEQAAKNAIWIDCGIHAREWISPAFCLWFIG 196
PD+ ++ IG SFE P+YVLK S + + A+W++ GIH+REWIS A +W
Sbjct: 137 AADFPDLARRVKIGHSFENRPMYVLKFSTGKGVRRPAVWLNAGIHSREWISQATAIWTAR 196
Query: 197 -------------------------------------HNRMWRKNRSFYANNHCIGTDLN 219
NR+WRK RS + CIG D N
Sbjct: 197 KIVSDYQRDPAITSILEKMDIFLLPVANPDGYVYTQTQNRLWRKTRSRNPGSSCIGADPN 256
Query: 220 RNFASKHWCEEGASSSSCSETYCGLYPESEPEVKAVASFLRRNINQIKAYISMHSYSQHI 279
RN+ + + +GAS + CSE Y G + SE EVK+V F++++ N K +I +HSYSQ +
Sbjct: 257 RNWNAS-FAGKGASDNPCSEVYHGPHANSEVEVKSVVDFIQKHGN-FKGFIDLHSYSQLL 314
Query: 280 VFPYSYTRSKSKDHEELSLVASEAVRAIEKTSKNTRYTHGHGSETLYLAPGGGDDWIYDL 339
++PY Y+ K+ D EEL VA A +A+ S T Y G T+Y A G DW YD
Sbjct: 315 MYPYGYSVKKAPDAEELDKVARLAAKALASVS-GTEYQVGPTCTTVYPASGSSIDWAYDN 373
Query: 340 GIKYSVT 346
GIK++ T
Sbjct: 374 GIKFAFT 380
>gi|188536055 carboxypeptidase A5 isoform 2 [Homo sapiens]
Length = 403
Score = 159 bits (402), Expect = 4e-39
Identities = 107/317 (33%), Positives = 159/317 (50%), Gaps = 50/317 (15%)
Query: 23 FQSGQVLAALPRTSRQVQVLQNLT--TTYEIVLWQPVTADLIVKKKQVHFFVNASDVDNV 80
F QVL L + +Q+ +L +L ++ W+ + +V F S++ ++
Sbjct: 37 FTGDQVLRVLAKDEKQLSLLGDLEGLKPQKVDFWRGPARPSLPVDMRVPF----SELKDI 92
Query: 81 KAHLNVSGIPCSVLLADVEDLIQQQISNDTVSPRASASY----YEQYHSLNEIYSWIEFI 136
KA+L G+ S+++ D++ L+ ++ S R S Y YH+L EIYSWI+
Sbjct: 93 KAYLESHGLAYSIMIKDIQVLLDEERQAMAKSRRLERSTNSFSYSSYHTLEEIYSWIDNF 152
Query: 137 TERHPDMLTKIHIGSSFEKYPLYVLKVSGKEQAAKNAIWIDCGIHAREWISPAFCLW--- 193
H D+++KI IG+SFE + VLK S + AIWID GIH+REWI+ A +W
Sbjct: 153 VMEHSDIVSKIQIGNSFENQSILVLKFS-TGGSRHPAIWIDTGIHSREWITHATGIWTAN 211
Query: 194 ---------------------FI-------------GHNRMWRKNRSFYANNHCIGTDLN 219
FI NR+WRKN+S CIG DLN
Sbjct: 212 KIVSDYGKDRVLTDILNAMDIFIELVTNPDGFAFTHSMNRLWRKNKSIRPGIFCIGVDLN 271
Query: 220 RNFASKHWCEEGASSSSCSETYCGLYPESEPEVKAVASFLRRNINQIKAYISMHSYSQHI 279
RN+ S + G++S+ CSETY G P+SEPEV A+ +F+ + N KA IS+HSYSQ +
Sbjct: 272 RNWKS-GFGGNGSNSNPCSETYHGPSPQSEPEVAAIVNFITAHGN-FKALISIHSYSQML 329
Query: 280 VFPYSYTRSKSKDHEEL 296
++PY + EL
Sbjct: 330 MYPYGRLLEPVSNQREL 346
>gi|188536069 carboxypeptidase A6 isoform 2 [Homo sapiens]
Length = 193
Score = 83.6 bits (205), Expect = 3e-16
Identities = 46/137 (33%), Positives = 63/137 (45%), Gaps = 39/137 (28%)
Query: 136 ITERHPDMLTKIHIGSSFEKYPLYVLKVSGKEQAAKNAIWIDCGIHAREWISPAFCLWFI 195
+ + H ++ IG S+E L++LK+ G+ K A+WIDCGIHAREWI PAFC WF+
Sbjct: 4 LNKTHSGLIHMFSIGRSYEGRSLFILKL-GRRSRLKRAVWIDCGIHAREWIGPAFCQWFV 62
Query: 196 -------------------------------------GHNRMWRKNRSFYANNHCIGTDL 218
++R WRK RS + C G D
Sbjct: 63 KEALLTYKSDPAMRKMLNHLYFYIMPVFNVDGYHFSWTNDRFWRKTRSRNSRFRCRGVDA 122
Query: 219 NRNFASKHWCEEGASSS 235
NRN+ K WC+ + SS
Sbjct: 123 NRNWKVK-WCDVSSGSS 138
>gi|7661910 tetratricopeptide repeat domain 35 [Homo sapiens]
Length = 297
Score = 34.7 bits (78), Expect = 0.14
Identities = 32/139 (23%), Positives = 57/139 (41%), Gaps = 23/139 (16%)
Query: 194 FIGHNRMWRKNRSFYANNHCIGTDLNRNFASKHWC-EEGASSSSCSETYCGLYPE----- 247
F+G W + Y N H ++A +C EE ++ + YC Y E
Sbjct: 151 FVGDQEAWHELAELYINEH--------DYAKAAFCLEELMMTNPHNHLYCQQYAEVKYTQ 202
Query: 248 -----SEPEVKAVASFLRRNINQIKAYISMHSYSQHIVF-PYSYTRSKSKDHEELSLVAS 301
E K A L+ N ++A ++ + HI P + ++K + + S AS
Sbjct: 203 GGLENLELSRKYFAQALKLNNRNMRALFGLYMSASHIASNPKASAKTKKDNMKYASWAAS 262
Query: 302 EAVRAIE---KTSKNTRYT 317
+ RA + ++ K T+Y+
Sbjct: 263 QINRAYQFAGRSKKETKYS 281
>gi|219842346 NADPH oxidase 4 isoform b [Homo sapiens]
Length = 538
Score = 30.4 bits (67), Expect = 2.6
Identities = 12/37 (32%), Positives = 19/37 (51%), Gaps = 3/37 (8%)
Query: 174 IWIDCGIHAREWISPAFCLWFIGHNRMWRKNRSFYAN 210
IW+ I + W + C+ HN+ W++NR Y N
Sbjct: 420 IWVCRDIQSFRWFADLLCML---HNKFWQENRPDYVN 453
>gi|219842348 NADPH oxidase 4 isoform c [Homo sapiens]
Length = 554
Score = 30.4 bits (67), Expect = 2.6
Identities = 12/37 (32%), Positives = 19/37 (51%), Gaps = 3/37 (8%)
Query: 174 IWIDCGIHAREWISPAFCLWFIGHNRMWRKNRSFYAN 210
IW+ I + W + C+ HN+ W++NR Y N
Sbjct: 436 IWVCRDIQSFRWFADLLCML---HNKFWQENRPDYVN 469
>gi|8393843 NADPH oxidase 4 isoform a [Homo sapiens]
Length = 578
Score = 30.4 bits (67), Expect = 2.6
Identities = 12/37 (32%), Positives = 19/37 (51%), Gaps = 3/37 (8%)
Query: 174 IWIDCGIHAREWISPAFCLWFIGHNRMWRKNRSFYAN 210
IW+ I + W + C+ HN+ W++NR Y N
Sbjct: 460 IWVCRDIQSFRWFADLLCML---HNKFWQENRPDYVN 493
>gi|34740327 zinc finger protein 804A [Homo sapiens]
Length = 1209
Score = 30.0 bits (66), Expect = 3.4
Identities = 21/77 (27%), Positives = 37/77 (48%), Gaps = 3/77 (3%)
Query: 239 ETYCGLYPESEPEVKAVASFLRRNINQIKAYISMHSYSQHIVFPYSYTRSKSKDHEELSL 298
ET C P S P K+ +R N N+I + + S + F Y+ S+ ++ ++ +
Sbjct: 126 ETVCA--PGSGPMFKSTTVTVRENCNEISQRVVVDSVNNQQDFKYTLIHSE-ENTKDATT 182
Query: 299 VASEAVRAIEKTSKNTR 315
VA + A T+KN +
Sbjct: 183 VAEDPESANNYTAKNNQ 199
>gi|4759248 tryptophan hydroxylase 1 [Homo sapiens]
Length = 444
Score = 29.6 bits (65), Expect = 4.4
Identities = 16/69 (23%), Positives = 34/69 (49%), Gaps = 5/69 (7%)
Query: 217 DLNRNFASKHWCEEGASSSSCSETYCGLYPESEPEVKAVASFLRR----NINQIKAYISM 272
+LN+ + + H C E + YCG ++ P+++ V++FL+ +I + Y+S
Sbjct: 180 ELNKLYPT-HACREYLKNLPLLSKYCGYREDNIPQLEDVSNFLKERTGFSIRPVAGYLSP 238
Query: 273 HSYSQHIVF 281
+ + F
Sbjct: 239 RDFLSGLAF 247
>gi|22202611 carboxypeptidase D precursor [Homo sapiens]
Length = 1380
Score = 28.9 bits (63), Expect = 7.5
Identities = 42/172 (24%), Positives = 67/172 (38%), Gaps = 38/172 (22%)
Query: 206 SFYANNHCIGTDLNRNFASKHWCEEGASSSSCSETYCGLYPESEPEVKAVASFLRRNINQ 265
S N+ DLNRNF + + + ++PE AV S+++
Sbjct: 621 SVIGRNNSNNFDLNRNFPDQ---------------FVQITDPTQPETIAVMSWMKSYPFV 665
Query: 266 IKAYISMHSYSQHIVFPYS------YTRSKSKDH---EELSLVASEAV------RAIEKT 310
+ A ++H S + +P+ T SKS D ++++L S+ R +
Sbjct: 666 LSA--NLHGGSLVVNYPFDDDEQGLATYSKSPDDAVFQQIALSYSKENSQMFQGRPCKNM 723
Query: 311 SKNTRYTHG-HGSETLYLAPGGGDDWIYDLGIKYSVT-----SNPPVEKLLP 356
N + HG + Y PGG DW Y + VT P+EK LP
Sbjct: 724 YPNEYFPHGITNGASWYNVPGGMQDWNYLQTNCFEVTIELGCVKYPLEKELP 775
>gi|9994201 carboxypeptidase X, member 1 precursor [Homo sapiens]
Length = 734
Score = 28.9 bits (63), Expect = 7.5
Identities = 15/66 (22%), Positives = 34/66 (51%), Gaps = 3/66 (4%)
Query: 122 QYHSLNEIYSWIEFITERHPDMLTKIHIGSSFEKYPLYVLKVS---GKEQAAKNAIWIDC 178
Q+H+ + ++ + E+ P++ IG S++ LYV+++S G+ + + +
Sbjct: 298 QHHNYKAMRKLMKQVQEQCPNITRIYSIGKSYQGLKLYVMEMSDKPGEHELGEPEVRYVA 357
Query: 179 GIHARE 184
G+H E
Sbjct: 358 GMHGNE 363
>gi|38348244 hypothetical protein LOC200844 [Homo sapiens]
Length = 563
Score = 28.9 bits (63), Expect = 7.5
Identities = 37/154 (24%), Positives = 60/154 (38%), Gaps = 32/154 (20%)
Query: 210 NNHCIGTDLNRNFASKH--WCEEGASSSSCSETYCG--LYPESEPEVKAVASFLRRNINQ 265
NN I ++ R+ SK+ C+ + T L PESE + + NI+Q
Sbjct: 152 NNMKISSETVRSVGSKNNRSCQPSTVEKCVNGTEMSALLIPESEEQGN------KENIHQ 205
Query: 266 IKAYISMHSYSQHIVFPYS---------------YTRSKSKDHEELSLVASEAVRAIE-K 309
IK + +H+ + HI+ P+ +S S++ E +S IE K
Sbjct: 206 IKQTVPIHAANLHIMHPHPPQEPSADKNNNRRRLRLKSTSRERTETPSGSSSGNNRIEDK 265
Query: 310 TSKNTRYTHGHGSETLY------LAPGGGDDWIY 337
S G+E L +P D+WI+
Sbjct: 266 ASTILTTVSQQGAELLNSGTLGPQSPDQSDEWIF 299
>gi|12707562 period 2 [Homo sapiens]
Length = 1255
Score = 28.5 bits (62), Expect = 9.8
Identities = 35/159 (22%), Positives = 56/159 (35%), Gaps = 33/159 (20%)
Query: 201 WRKNRSFYANNHCIGTD-LNRNFASKHWCEEGASSSSCSETYCGLYPESEPEVKAVASFL 259
W + SF H + LN + + H C E + L+P + + + L
Sbjct: 421 WSRKISFIIGRHKVRVGPLNEDVFAAHPCTEEKA----------LHPSIQELTEQIHRLL 470
Query: 260 RRNI--NQIKAYISMHSYSQHIVFPYSYTRSKSKDHEELSLVASEAVRAIEKTSKNTRYT 317
+ + + Y S+ S H + S S HE+ +E + KT + Y+
Sbjct: 471 LQPVPHSGSSGYGSLGSNGSHEHLMSQTSSSDSNGHEDSRRRRAEICKNGNKTKNRSHYS 530
Query: 318 HGHGSETLYLAPGGGDDWIYDLGIKYSVT---SNPPVEK 353
H G + K SVT +NPP EK
Sbjct: 531 HESGEQK-----------------KKSVTEMQTNPPAEK 552
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.132 0.407
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 13,653,757
Number of Sequences: 37866
Number of extensions: 559859
Number of successful extensions: 1331
Number of sequences better than 10.0: 23
Number of HSP's better than 10.0 without gapping: 13
Number of HSP's successfully gapped in prelim test: 10
Number of HSP's that attempted gapping in prelim test: 1268
Number of HSP's gapped (non-prelim): 36
length of query: 360
length of database: 18,247,518
effective HSP length: 103
effective length of query: 257
effective length of database: 14,347,320
effective search space: 3687261240
effective search space used: 3687261240
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.