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Search of human proteins with 41872507
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|41872507 diacylglycerol kinase zeta isoform 2 [Homo sapiens]
(929 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|41872507 diacylglycerol kinase zeta isoform 2 [Homo sapiens] 1917 0.0
gi|41872522 diacylglycerol kinase zeta isoform 1 [Homo sapiens] 1810 0.0
gi|41872527 diacylglycerol kinase zeta isoform 3 [Homo sapiens] 1810 0.0
gi|157688564 diacylglycerol kinase zeta isoform 4 [Homo sapiens] 1803 0.0
gi|4758156 diacylglycerol kinase, iota [Homo sapiens] 1165 0.0
gi|22027632 diacylglycerol kinase, beta isoform 1 [Homo sapiens] 293 4e-79
gi|124256476 diacylglycerol kinase gamma isoform 1 [Homo sapiens] 288 2e-77
gi|22027634 diacylglycerol kinase, beta isoform 2 [Homo sapiens] 285 1e-76
gi|41872494 diacylglycerol kinase, alpha 80kDa [Homo sapiens] 279 8e-75
gi|41393587 diacylglycerol kinase, alpha 80kDa [Homo sapiens] 279 8e-75
gi|31542504 diacylglycerol kinase, alpha 80kDa [Homo sapiens] 279 8e-75
gi|41872500 diacylglycerol kinase, alpha 80kDa [Homo sapiens] 279 8e-75
gi|124256482 diacylglycerol kinase gamma isoform 3 [Homo sapiens] 270 6e-72
gi|124256474 diacylglycerol kinase gamma isoform 2 [Homo sapiens] 249 6e-66
gi|40806175 diacylglycerol kinase, theta [Homo sapiens] 238 3e-62
gi|4503313 diacylglycerol kinase epsilon [Homo sapiens] 217 4e-56
gi|29788760 diacylglycerol kinase, eta isoform 1 [Homo sapiens] 152 1e-36
gi|29788751 diacylglycerol kinase, eta isoform 2 [Homo sapiens] 152 1e-36
gi|25777596 diacylglycerol kinase, delta 130kDa isoform 1 [Homo ... 151 3e-36
gi|25777598 diacylglycerol kinase, delta 130kDa isoform 2 [Homo ... 151 3e-36
gi|62000702 diacylglycerol kinase kappa [Homo sapiens] 134 4e-31
gi|223634006 hypothetical protein LOC441869 [Homo sapiens] 57 6e-08
gi|20270347 ankyrin repeat domain 54 [Homo sapiens] 54 9e-07
gi|225543463 tetratricopeptide repeat, ankyrin repeat and coiled... 53 1e-06
gi|225543461 tetratricopeptide repeat, ankyrin repeat and coiled... 53 1e-06
gi|219842212 protein phosphatase 1, regulatory (inhibitor) subun... 51 6e-06
gi|4505317 protein phosphatase 1, regulatory (inhibitor) subunit... 51 6e-06
gi|134948605 ankyrin repeat domain 12 isoform 2 [Homo sapiens] 50 7e-06
gi|134948558 ankyrin repeat domain 12 isoform 1 [Homo sapiens] 50 7e-06
gi|87239981 tankyrase, TRF1-interacting ankyrin-related ADP-ribo... 50 7e-06
>gi|41872507 diacylglycerol kinase zeta isoform 2 [Homo sapiens]
Length = 929
Score = 1917 bits (4965), Expect = 0.0
Identities = 929/929 (100%), Positives = 929/929 (100%)
Query: 1 MEPRDGSPEARSSDSESASASSSGSERDAGPEPDKAPRRLNKRRFPGLRLFGHRKAITKS 60
MEPRDGSPEARSSDSESASASSSGSERDAGPEPDKAPRRLNKRRFPGLRLFGHRKAITKS
Sbjct: 1 MEPRDGSPEARSSDSESASASSSGSERDAGPEPDKAPRRLNKRRFPGLRLFGHRKAITKS 60
Query: 61 GLQHLAPPPPTPGAPCSESERQIRSTVDWSESATYGEHIWFETNVSGDFCYVGEQYCVAR 120
GLQHLAPPPPTPGAPCSESERQIRSTVDWSESATYGEHIWFETNVSGDFCYVGEQYCVAR
Sbjct: 61 GLQHLAPPPPTPGAPCSESERQIRSTVDWSESATYGEHIWFETNVSGDFCYVGEQYCVAR 120
Query: 121 MLQKSVSRRKCAACKIVVHTPCIEQLEKINFRCKPSFRESGSRNVREPTFVRHHWVHRRR 180
MLQKSVSRRKCAACKIVVHTPCIEQLEKINFRCKPSFRESGSRNVREPTFVRHHWVHRRR
Sbjct: 121 MLQKSVSRRKCAACKIVVHTPCIEQLEKINFRCKPSFRESGSRNVREPTFVRHHWVHRRR 180
Query: 181 QDGKCRHCGKGFQQKFTFHSKEIVAISCSWCKQAYHSKVSCFMLQQIEEPCSLGVHAAVV 240
QDGKCRHCGKGFQQKFTFHSKEIVAISCSWCKQAYHSKVSCFMLQQIEEPCSLGVHAAVV
Sbjct: 181 QDGKCRHCGKGFQQKFTFHSKEIVAISCSWCKQAYHSKVSCFMLQQIEEPCSLGVHAAVV 240
Query: 241 IPPTWILRARRPQNTLKASKKKKRASFKRKSSKKGPEEGRWRPFIIRPTPSPLMKPLLVF 300
IPPTWILRARRPQNTLKASKKKKRASFKRKSSKKGPEEGRWRPFIIRPTPSPLMKPLLVF
Sbjct: 241 IPPTWILRARRPQNTLKASKKKKRASFKRKSSKKGPEEGRWRPFIIRPTPSPLMKPLLVF 300
Query: 301 VNPKSGGNQGAKIIQSFLWYLNPRQVFDLSQGGPKEALEMYRKVHNLRILACGGDGTVGW 360
VNPKSGGNQGAKIIQSFLWYLNPRQVFDLSQGGPKEALEMYRKVHNLRILACGGDGTVGW
Sbjct: 301 VNPKSGGNQGAKIIQSFLWYLNPRQVFDLSQGGPKEALEMYRKVHNLRILACGGDGTVGW 360
Query: 361 ILSTLDQLRLKPPPPVAILPLGTGNDLARTLNWGGGYTDEPVSKILSHVEEGNVVQLDRW 420
ILSTLDQLRLKPPPPVAILPLGTGNDLARTLNWGGGYTDEPVSKILSHVEEGNVVQLDRW
Sbjct: 361 ILSTLDQLRLKPPPPVAILPLGTGNDLARTLNWGGGYTDEPVSKILSHVEEGNVVQLDRW 420
Query: 421 DLHAEPNPEAGPEDRDEGATDRLPLDVFNNYFSLGFDAHVTLEFHESREANPEKFNSRFR 480
DLHAEPNPEAGPEDRDEGATDRLPLDVFNNYFSLGFDAHVTLEFHESREANPEKFNSRFR
Sbjct: 421 DLHAEPNPEAGPEDRDEGATDRLPLDVFNNYFSLGFDAHVTLEFHESREANPEKFNSRFR 480
Query: 481 NKMFYAGTAFSDFLMGSSKDLAKHIRVVCDGMDLTPKIQDLKPQCVVFLNIPRYCAGTMP 540
NKMFYAGTAFSDFLMGSSKDLAKHIRVVCDGMDLTPKIQDLKPQCVVFLNIPRYCAGTMP
Sbjct: 481 NKMFYAGTAFSDFLMGSSKDLAKHIRVVCDGMDLTPKIQDLKPQCVVFLNIPRYCAGTMP 540
Query: 541 WGHPGEHHDFEPQRHDDGYLEVIGFTMTSLAALQVGGHGERLTQCREVVLTTSKAIPVQV 600
WGHPGEHHDFEPQRHDDGYLEVIGFTMTSLAALQVGGHGERLTQCREVVLTTSKAIPVQV
Sbjct: 541 WGHPGEHHDFEPQRHDDGYLEVIGFTMTSLAALQVGGHGERLTQCREVVLTTSKAIPVQV 600
Query: 601 DGEPCKLAASRIRIALRNQATMVQKAKRRSAAPLHSDQQPVPEQLRIQVSRVSMHDYEAL 660
DGEPCKLAASRIRIALRNQATMVQKAKRRSAAPLHSDQQPVPEQLRIQVSRVSMHDYEAL
Sbjct: 601 DGEPCKLAASRIRIALRNQATMVQKAKRRSAAPLHSDQQPVPEQLRIQVSRVSMHDYEAL 660
Query: 661 HYDKEQLKEASVPLGTVVVPGDSDLELCRAHIERLQQEPDGAGAKSPTCQKLSPKWCFLD 720
HYDKEQLKEASVPLGTVVVPGDSDLELCRAHIERLQQEPDGAGAKSPTCQKLSPKWCFLD
Sbjct: 661 HYDKEQLKEASVPLGTVVVPGDSDLELCRAHIERLQQEPDGAGAKSPTCQKLSPKWCFLD 720
Query: 721 ATTASRFYRIDRAQEHLNYVTEIAQDEIYILDPELLGASARPDLPTPTSPLPTSPCSPTP 780
ATTASRFYRIDRAQEHLNYVTEIAQDEIYILDPELLGASARPDLPTPTSPLPTSPCSPTP
Sbjct: 721 ATTASRFYRIDRAQEHLNYVTEIAQDEIYILDPELLGASARPDLPTPTSPLPTSPCSPTP 780
Query: 781 RSLQGDAAPPQGEELIEAAKRNDFCKLQELHRAGGDLMHRDEQSRTLLHHAVSTGSKDVV 840
RSLQGDAAPPQGEELIEAAKRNDFCKLQELHRAGGDLMHRDEQSRTLLHHAVSTGSKDVV
Sbjct: 781 RSLQGDAAPPQGEELIEAAKRNDFCKLQELHRAGGDLMHRDEQSRTLLHHAVSTGSKDVV 840
Query: 841 RYLLDHAPPEILDAVEENGETCLHQAAALGQRTICHYIVEAGASLMKTDQQGDTPRQRAE 900
RYLLDHAPPEILDAVEENGETCLHQAAALGQRTICHYIVEAGASLMKTDQQGDTPRQRAE
Sbjct: 841 RYLLDHAPPEILDAVEENGETCLHQAAALGQRTICHYIVEAGASLMKTDQQGDTPRQRAE 900
Query: 901 KAQDTELAAYLENRQHYQMIQREDQETAV 929
KAQDTELAAYLENRQHYQMIQREDQETAV
Sbjct: 901 KAQDTELAAYLENRQHYQMIQREDQETAV 929
>gi|41872522 diacylglycerol kinase zeta isoform 1 [Homo sapiens]
Length = 945
Score = 1810 bits (4687), Expect = 0.0
Identities = 885/920 (96%), Positives = 894/920 (97%), Gaps = 7/920 (0%)
Query: 11 RSSDSESASASSSGSERDA-GPEPDKAPRRLNKRRFPGLRLFGHRKAITKSGLQHLAPPP 69
R +++ A GS A GP ++ R+L+ R+ +RKAITKSGLQHLAPPP
Sbjct: 32 RGEEAQVAQPWPEGSRGTAAGPPVEERFRQLHLRK-----QVSYRKAITKSGLQHLAPPP 86
Query: 70 PTPGAPCSESERQIRSTVDWSESATYGEHIWFETNVSGDFCYVGEQYCVARMLQKSVSRR 129
PTPGAPCSESERQIRSTVDWSESATYGEHIWFETNVSGDFCYVGEQYCVARML KSVSRR
Sbjct: 87 PTPGAPCSESERQIRSTVDWSESATYGEHIWFETNVSGDFCYVGEQYCVARML-KSVSRR 145
Query: 130 KCAACKIVVHTPCIEQLEKINFRCKPSFRESGSRNVREPTFVRHHWVHRRRQDGKCRHCG 189
KCAACKIVVHTPCIEQLEKINFRCKPSFRESGSRNVREPTFVRHHWVHRRRQDGKCRHCG
Sbjct: 146 KCAACKIVVHTPCIEQLEKINFRCKPSFRESGSRNVREPTFVRHHWVHRRRQDGKCRHCG 205
Query: 190 KGFQQKFTFHSKEIVAISCSWCKQAYHSKVSCFMLQQIEEPCSLGVHAAVVIPPTWILRA 249
KGFQQKFTFHSKEIVAISCSWCKQAYHSKVSCFMLQQIEEPCSLGVHAAVVIPPTWILRA
Sbjct: 206 KGFQQKFTFHSKEIVAISCSWCKQAYHSKVSCFMLQQIEEPCSLGVHAAVVIPPTWILRA 265
Query: 250 RRPQNTLKASKKKKRASFKRKSSKKGPEEGRWRPFIIRPTPSPLMKPLLVFVNPKSGGNQ 309
RRPQNTLKASKKKKRASFKRKSSKKGPEEGRWRPFIIRPTPSPLMKPLLVFVNPKSGGNQ
Sbjct: 266 RRPQNTLKASKKKKRASFKRKSSKKGPEEGRWRPFIIRPTPSPLMKPLLVFVNPKSGGNQ 325
Query: 310 GAKIIQSFLWYLNPRQVFDLSQGGPKEALEMYRKVHNLRILACGGDGTVGWILSTLDQLR 369
GAKIIQSFLWYLNPRQVFDLSQGGPKEALEMYRKVHNLRILACGGDGTVGWILSTLDQLR
Sbjct: 326 GAKIIQSFLWYLNPRQVFDLSQGGPKEALEMYRKVHNLRILACGGDGTVGWILSTLDQLR 385
Query: 370 LKPPPPVAILPLGTGNDLARTLNWGGGYTDEPVSKILSHVEEGNVVQLDRWDLHAEPNPE 429
LKPPPPVAILPLGTGNDLARTLNWGGGYTDEPVSKILSHVEEGNVVQLDRWDLHAEPNPE
Sbjct: 386 LKPPPPVAILPLGTGNDLARTLNWGGGYTDEPVSKILSHVEEGNVVQLDRWDLHAEPNPE 445
Query: 430 AGPEDRDEGATDRLPLDVFNNYFSLGFDAHVTLEFHESREANPEKFNSRFRNKMFYAGTA 489
AGPEDRDEGATDRLPLDVFNNYFSLGFDAHVTLEFHESREANPEKFNSRFRNKMFYAGTA
Sbjct: 446 AGPEDRDEGATDRLPLDVFNNYFSLGFDAHVTLEFHESREANPEKFNSRFRNKMFYAGTA 505
Query: 490 FSDFLMGSSKDLAKHIRVVCDGMDLTPKIQDLKPQCVVFLNIPRYCAGTMPWGHPGEHHD 549
FSDFLMGSSKDLAKHIRVVCDGMDLTPKIQDLKPQCVVFLNIPRYCAGTMPWGHPGEHHD
Sbjct: 506 FSDFLMGSSKDLAKHIRVVCDGMDLTPKIQDLKPQCVVFLNIPRYCAGTMPWGHPGEHHD 565
Query: 550 FEPQRHDDGYLEVIGFTMTSLAALQVGGHGERLTQCREVVLTTSKAIPVQVDGEPCKLAA 609
FEPQRHDDGYLEVIGFTMTSLAALQVGGHGERLTQCREVVLTTSKAIPVQVDGEPCKLAA
Sbjct: 566 FEPQRHDDGYLEVIGFTMTSLAALQVGGHGERLTQCREVVLTTSKAIPVQVDGEPCKLAA 625
Query: 610 SRIRIALRNQATMVQKAKRRSAAPLHSDQQPVPEQLRIQVSRVSMHDYEALHYDKEQLKE 669
SRIRIALRNQATMVQKAKRRSAAPLHSDQQPVPEQLRIQVSRVSMHDYEALHYDKEQLKE
Sbjct: 626 SRIRIALRNQATMVQKAKRRSAAPLHSDQQPVPEQLRIQVSRVSMHDYEALHYDKEQLKE 685
Query: 670 ASVPLGTVVVPGDSDLELCRAHIERLQQEPDGAGAKSPTCQKLSPKWCFLDATTASRFYR 729
ASVPLGTVVVPGDSDLELCRAHIERLQQEPDGAGAKSPTCQKLSPKWCFLDATTASRFYR
Sbjct: 686 ASVPLGTVVVPGDSDLELCRAHIERLQQEPDGAGAKSPTCQKLSPKWCFLDATTASRFYR 745
Query: 730 IDRAQEHLNYVTEIAQDEIYILDPELLGASARPDLPTPTSPLPTSPCSPTPRSLQGDAAP 789
IDRAQEHLNYVTEIAQDEIYILDPELLGASARPDLPTPTSPLPTSPCSPTPRSLQGDAAP
Sbjct: 746 IDRAQEHLNYVTEIAQDEIYILDPELLGASARPDLPTPTSPLPTSPCSPTPRSLQGDAAP 805
Query: 790 PQGEELIEAAKRNDFCKLQELHRAGGDLMHRDEQSRTLLHHAVSTGSKDVVRYLLDHAPP 849
PQGEELIEAAKRNDFCKLQELHRAGGDLMHRDEQSRTLLHHAVSTGSKDVVRYLLDHAPP
Sbjct: 806 PQGEELIEAAKRNDFCKLQELHRAGGDLMHRDEQSRTLLHHAVSTGSKDVVRYLLDHAPP 865
Query: 850 EILDAVEENGETCLHQAAALGQRTICHYIVEAGASLMKTDQQGDTPRQRAEKAQDTELAA 909
EILDAVEENGETCLHQAAALGQRTICHYIVEAGASLMKTDQQGDTPRQRAEKAQDTELAA
Sbjct: 866 EILDAVEENGETCLHQAAALGQRTICHYIVEAGASLMKTDQQGDTPRQRAEKAQDTELAA 925
Query: 910 YLENRQHYQMIQREDQETAV 929
YLENRQHYQMIQREDQETAV
Sbjct: 926 YLENRQHYQMIQREDQETAV 945
>gi|41872527 diacylglycerol kinase zeta isoform 3 [Homo sapiens]
Length = 895
Score = 1810 bits (4687), Expect = 0.0
Identities = 875/876 (99%), Positives = 876/876 (100%)
Query: 54 RKAITKSGLQHLAPPPPTPGAPCSESERQIRSTVDWSESATYGEHIWFETNVSGDFCYVG 113
+KAITKSGLQHLAPPPPTPGAPCSESERQIRSTVDWSESATYGEHIWFETNVSGDFCYVG
Sbjct: 20 QKAITKSGLQHLAPPPPTPGAPCSESERQIRSTVDWSESATYGEHIWFETNVSGDFCYVG 79
Query: 114 EQYCVARMLQKSVSRRKCAACKIVVHTPCIEQLEKINFRCKPSFRESGSRNVREPTFVRH 173
EQYCVARMLQKSVSRRKCAACKIVVHTPCIEQLEKINFRCKPSFRESGSRNVREPTFVRH
Sbjct: 80 EQYCVARMLQKSVSRRKCAACKIVVHTPCIEQLEKINFRCKPSFRESGSRNVREPTFVRH 139
Query: 174 HWVHRRRQDGKCRHCGKGFQQKFTFHSKEIVAISCSWCKQAYHSKVSCFMLQQIEEPCSL 233
HWVHRRRQDGKCRHCGKGFQQKFTFHSKEIVAISCSWCKQAYHSKVSCFMLQQIEEPCSL
Sbjct: 140 HWVHRRRQDGKCRHCGKGFQQKFTFHSKEIVAISCSWCKQAYHSKVSCFMLQQIEEPCSL 199
Query: 234 GVHAAVVIPPTWILRARRPQNTLKASKKKKRASFKRKSSKKGPEEGRWRPFIIRPTPSPL 293
GVHAAVVIPPTWILRARRPQNTLKASKKKKRASFKRKSSKKGPEEGRWRPFIIRPTPSPL
Sbjct: 200 GVHAAVVIPPTWILRARRPQNTLKASKKKKRASFKRKSSKKGPEEGRWRPFIIRPTPSPL 259
Query: 294 MKPLLVFVNPKSGGNQGAKIIQSFLWYLNPRQVFDLSQGGPKEALEMYRKVHNLRILACG 353
MKPLLVFVNPKSGGNQGAKIIQSFLWYLNPRQVFDLSQGGPKEALEMYRKVHNLRILACG
Sbjct: 260 MKPLLVFVNPKSGGNQGAKIIQSFLWYLNPRQVFDLSQGGPKEALEMYRKVHNLRILACG 319
Query: 354 GDGTVGWILSTLDQLRLKPPPPVAILPLGTGNDLARTLNWGGGYTDEPVSKILSHVEEGN 413
GDGTVGWILSTLDQLRLKPPPPVAILPLGTGNDLARTLNWGGGYTDEPVSKILSHVEEGN
Sbjct: 320 GDGTVGWILSTLDQLRLKPPPPVAILPLGTGNDLARTLNWGGGYTDEPVSKILSHVEEGN 379
Query: 414 VVQLDRWDLHAEPNPEAGPEDRDEGATDRLPLDVFNNYFSLGFDAHVTLEFHESREANPE 473
VVQLDRWDLHAEPNPEAGPEDRDEGATDRLPLDVFNNYFSLGFDAHVTLEFHESREANPE
Sbjct: 380 VVQLDRWDLHAEPNPEAGPEDRDEGATDRLPLDVFNNYFSLGFDAHVTLEFHESREANPE 439
Query: 474 KFNSRFRNKMFYAGTAFSDFLMGSSKDLAKHIRVVCDGMDLTPKIQDLKPQCVVFLNIPR 533
KFNSRFRNKMFYAGTAFSDFLMGSSKDLAKHIRVVCDGMDLTPKIQDLKPQCVVFLNIPR
Sbjct: 440 KFNSRFRNKMFYAGTAFSDFLMGSSKDLAKHIRVVCDGMDLTPKIQDLKPQCVVFLNIPR 499
Query: 534 YCAGTMPWGHPGEHHDFEPQRHDDGYLEVIGFTMTSLAALQVGGHGERLTQCREVVLTTS 593
YCAGTMPWGHPGEHHDFEPQRHDDGYLEVIGFTMTSLAALQVGGHGERLTQCREVVLTTS
Sbjct: 500 YCAGTMPWGHPGEHHDFEPQRHDDGYLEVIGFTMTSLAALQVGGHGERLTQCREVVLTTS 559
Query: 594 KAIPVQVDGEPCKLAASRIRIALRNQATMVQKAKRRSAAPLHSDQQPVPEQLRIQVSRVS 653
KAIPVQVDGEPCKLAASRIRIALRNQATMVQKAKRRSAAPLHSDQQPVPEQLRIQVSRVS
Sbjct: 560 KAIPVQVDGEPCKLAASRIRIALRNQATMVQKAKRRSAAPLHSDQQPVPEQLRIQVSRVS 619
Query: 654 MHDYEALHYDKEQLKEASVPLGTVVVPGDSDLELCRAHIERLQQEPDGAGAKSPTCQKLS 713
MHDYEALHYDKEQLKEASVPLGTVVVPGDSDLELCRAHIERLQQEPDGAGAKSPTCQKLS
Sbjct: 620 MHDYEALHYDKEQLKEASVPLGTVVVPGDSDLELCRAHIERLQQEPDGAGAKSPTCQKLS 679
Query: 714 PKWCFLDATTASRFYRIDRAQEHLNYVTEIAQDEIYILDPELLGASARPDLPTPTSPLPT 773
PKWCFLDATTASRFYRIDRAQEHLNYVTEIAQDEIYILDPELLGASARPDLPTPTSPLPT
Sbjct: 680 PKWCFLDATTASRFYRIDRAQEHLNYVTEIAQDEIYILDPELLGASARPDLPTPTSPLPT 739
Query: 774 SPCSPTPRSLQGDAAPPQGEELIEAAKRNDFCKLQELHRAGGDLMHRDEQSRTLLHHAVS 833
SPCSPTPRSLQGDAAPPQGEELIEAAKRNDFCKLQELHRAGGDLMHRDEQSRTLLHHAVS
Sbjct: 740 SPCSPTPRSLQGDAAPPQGEELIEAAKRNDFCKLQELHRAGGDLMHRDEQSRTLLHHAVS 799
Query: 834 TGSKDVVRYLLDHAPPEILDAVEENGETCLHQAAALGQRTICHYIVEAGASLMKTDQQGD 893
TGSKDVVRYLLDHAPPEILDAVEENGETCLHQAAALGQRTICHYIVEAGASLMKTDQQGD
Sbjct: 800 TGSKDVVRYLLDHAPPEILDAVEENGETCLHQAAALGQRTICHYIVEAGASLMKTDQQGD 859
Query: 894 TPRQRAEKAQDTELAAYLENRQHYQMIQREDQETAV 929
TPRQRAEKAQDTELAAYLENRQHYQMIQREDQETAV
Sbjct: 860 TPRQRAEKAQDTELAAYLENRQHYQMIQREDQETAV 895
>gi|157688564 diacylglycerol kinase zeta isoform 4 [Homo sapiens]
Length = 1117
Score = 1803 bits (4669), Expect = 0.0
Identities = 874/875 (99%), Positives = 874/875 (99%), Gaps = 1/875 (0%)
Query: 55 KAITKSGLQHLAPPPPTPGAPCSESERQIRSTVDWSESATYGEHIWFETNVSGDFCYVGE 114
KAITKSGLQHLAPPPPTPGAPCSESERQIRSTVDWSESATYGEHIWFETNVSGDFCYVGE
Sbjct: 244 KAITKSGLQHLAPPPPTPGAPCSESERQIRSTVDWSESATYGEHIWFETNVSGDFCYVGE 303
Query: 115 QYCVARMLQKSVSRRKCAACKIVVHTPCIEQLEKINFRCKPSFRESGSRNVREPTFVRHH 174
QYCVARML KSVSRRKCAACKIVVHTPCIEQLEKINFRCKPSFRESGSRNVREPTFVRHH
Sbjct: 304 QYCVARML-KSVSRRKCAACKIVVHTPCIEQLEKINFRCKPSFRESGSRNVREPTFVRHH 362
Query: 175 WVHRRRQDGKCRHCGKGFQQKFTFHSKEIVAISCSWCKQAYHSKVSCFMLQQIEEPCSLG 234
WVHRRRQDGKCRHCGKGFQQKFTFHSKEIVAISCSWCKQAYHSKVSCFMLQQIEEPCSLG
Sbjct: 363 WVHRRRQDGKCRHCGKGFQQKFTFHSKEIVAISCSWCKQAYHSKVSCFMLQQIEEPCSLG 422
Query: 235 VHAAVVIPPTWILRARRPQNTLKASKKKKRASFKRKSSKKGPEEGRWRPFIIRPTPSPLM 294
VHAAVVIPPTWILRARRPQNTLKASKKKKRASFKRKSSKKGPEEGRWRPFIIRPTPSPLM
Sbjct: 423 VHAAVVIPPTWILRARRPQNTLKASKKKKRASFKRKSSKKGPEEGRWRPFIIRPTPSPLM 482
Query: 295 KPLLVFVNPKSGGNQGAKIIQSFLWYLNPRQVFDLSQGGPKEALEMYRKVHNLRILACGG 354
KPLLVFVNPKSGGNQGAKIIQSFLWYLNPRQVFDLSQGGPKEALEMYRKVHNLRILACGG
Sbjct: 483 KPLLVFVNPKSGGNQGAKIIQSFLWYLNPRQVFDLSQGGPKEALEMYRKVHNLRILACGG 542
Query: 355 DGTVGWILSTLDQLRLKPPPPVAILPLGTGNDLARTLNWGGGYTDEPVSKILSHVEEGNV 414
DGTVGWILSTLDQLRLKPPPPVAILPLGTGNDLARTLNWGGGYTDEPVSKILSHVEEGNV
Sbjct: 543 DGTVGWILSTLDQLRLKPPPPVAILPLGTGNDLARTLNWGGGYTDEPVSKILSHVEEGNV 602
Query: 415 VQLDRWDLHAEPNPEAGPEDRDEGATDRLPLDVFNNYFSLGFDAHVTLEFHESREANPEK 474
VQLDRWDLHAEPNPEAGPEDRDEGATDRLPLDVFNNYFSLGFDAHVTLEFHESREANPEK
Sbjct: 603 VQLDRWDLHAEPNPEAGPEDRDEGATDRLPLDVFNNYFSLGFDAHVTLEFHESREANPEK 662
Query: 475 FNSRFRNKMFYAGTAFSDFLMGSSKDLAKHIRVVCDGMDLTPKIQDLKPQCVVFLNIPRY 534
FNSRFRNKMFYAGTAFSDFLMGSSKDLAKHIRVVCDGMDLTPKIQDLKPQCVVFLNIPRY
Sbjct: 663 FNSRFRNKMFYAGTAFSDFLMGSSKDLAKHIRVVCDGMDLTPKIQDLKPQCVVFLNIPRY 722
Query: 535 CAGTMPWGHPGEHHDFEPQRHDDGYLEVIGFTMTSLAALQVGGHGERLTQCREVVLTTSK 594
CAGTMPWGHPGEHHDFEPQRHDDGYLEVIGFTMTSLAALQVGGHGERLTQCREVVLTTSK
Sbjct: 723 CAGTMPWGHPGEHHDFEPQRHDDGYLEVIGFTMTSLAALQVGGHGERLTQCREVVLTTSK 782
Query: 595 AIPVQVDGEPCKLAASRIRIALRNQATMVQKAKRRSAAPLHSDQQPVPEQLRIQVSRVSM 654
AIPVQVDGEPCKLAASRIRIALRNQATMVQKAKRRSAAPLHSDQQPVPEQLRIQVSRVSM
Sbjct: 783 AIPVQVDGEPCKLAASRIRIALRNQATMVQKAKRRSAAPLHSDQQPVPEQLRIQVSRVSM 842
Query: 655 HDYEALHYDKEQLKEASVPLGTVVVPGDSDLELCRAHIERLQQEPDGAGAKSPTCQKLSP 714
HDYEALHYDKEQLKEASVPLGTVVVPGDSDLELCRAHIERLQQEPDGAGAKSPTCQKLSP
Sbjct: 843 HDYEALHYDKEQLKEASVPLGTVVVPGDSDLELCRAHIERLQQEPDGAGAKSPTCQKLSP 902
Query: 715 KWCFLDATTASRFYRIDRAQEHLNYVTEIAQDEIYILDPELLGASARPDLPTPTSPLPTS 774
KWCFLDATTASRFYRIDRAQEHLNYVTEIAQDEIYILDPELLGASARPDLPTPTSPLPTS
Sbjct: 903 KWCFLDATTASRFYRIDRAQEHLNYVTEIAQDEIYILDPELLGASARPDLPTPTSPLPTS 962
Query: 775 PCSPTPRSLQGDAAPPQGEELIEAAKRNDFCKLQELHRAGGDLMHRDEQSRTLLHHAVST 834
PCSPTPRSLQGDAAPPQGEELIEAAKRNDFCKLQELHRAGGDLMHRDEQSRTLLHHAVST
Sbjct: 963 PCSPTPRSLQGDAAPPQGEELIEAAKRNDFCKLQELHRAGGDLMHRDEQSRTLLHHAVST 1022
Query: 835 GSKDVVRYLLDHAPPEILDAVEENGETCLHQAAALGQRTICHYIVEAGASLMKTDQQGDT 894
GSKDVVRYLLDHAPPEILDAVEENGETCLHQAAALGQRTICHYIVEAGASLMKTDQQGDT
Sbjct: 1023 GSKDVVRYLLDHAPPEILDAVEENGETCLHQAAALGQRTICHYIVEAGASLMKTDQQGDT 1082
Query: 895 PRQRAEKAQDTELAAYLENRQHYQMIQREDQETAV 929
PRQRAEKAQDTELAAYLENRQHYQMIQREDQETAV
Sbjct: 1083 PRQRAEKAQDTELAAYLENRQHYQMIQREDQETAV 1117
>gi|4758156 diacylglycerol kinase, iota [Homo sapiens]
Length = 1065
Score = 1165 bits (3013), Expect = 0.0
Identities = 589/995 (59%), Positives = 730/995 (73%), Gaps = 83/995 (8%)
Query: 5 DGSPEARSSDSESASASSSGSERDAGPEPDKAPRRLNK-RRFPGLRLFGHRKAITKSGLQ 63
+G + R + S +A+ +++ E A + +K K R + +RKAI+++GLQ
Sbjct: 84 EGGADPRGAGSAAAAGAAALDEPAAAGQKEKDEALEEKLRNLTFRKQVSYRKAISRAGLQ 143
Query: 64 HLAPPPPTPGAPCSESERQIRSTVDWSESATYGEHIWFETNVSGDFCYVGEQYCVARMLQ 123
HLAP P + ++ R+T+DWSE+A GEH+W ETNVSGD CY+GE+ C R
Sbjct: 144 HLAPAHPLSLPVANGPAKEPRATLDWSENAVNGEHLWLETNVSGDLCYLGEENCQVRFA- 202
Query: 124 KSVSRRKCAACKIVVHTPCIEQLEKINFRCKPSFRESGSRNVREPTFVRHHWVHRRRQDG 183
KS RRKCA CKIVVHT CIEQLEKINFRCKP+FRE GSR+ RE FVRHHWVHRRRQ+G
Sbjct: 203 KSALRRKCAVCKIVVHTACIEQLEKINFRCKPTFREGGSRSPRE-NFVRHHWVHRRRQEG 261
Query: 184 KCRHCGKGFQQKFTFHSKEIVAISCSWCKQAYHSKVSCFMLQQIEEPCSLGVHAAVVIPP 243
KC+ CGKGFQQKF+FHSKEIVAISCSWCKQA+H+KV+CFML IEEPCSLG HAAV++PP
Sbjct: 262 KCKQCGKGFQQKFSFHSKEIVAISCSWCKQAFHNKVTCFMLHHIEEPCSLGAHAAVIVPP 321
Query: 244 TWILRARRPQNTLKAS-KKKKRASFKRKSSKKGPE-EGRWRPFIIRPTPSPLMKPLLVFV 301
TWI++ ++PQN+LKAS +KKKR SFKRK+SK+G E E + RPF+I+P SPLMKPLLVFV
Sbjct: 322 TWIIKVKKPQNSLKASNRKKKRTSFKRKASKRGMEQENKGRPFVIKPISSPLMKPLLVFV 381
Query: 302 NPKSGGNQGAKIIQSFLWYLNPRQVFDLSQGGPKEALEMYRKVHNLRILACGGDGTVGWI 361
NPKSGGNQG K++Q F+WYLNPRQVFDLSQ GPK+ALE+YRKV NLRILACGGDGTVGWI
Sbjct: 382 NPKSGGNQGTKVLQMFMWYLNPRQVFDLSQEGPKDALELYRKVPNLRILACGGDGTVGWI 441
Query: 362 LSTLDQLRLKPPPPVAILPLGTGNDLARTLNWGGGYTDEPVSKILSHVEEGNVVQLDRWD 421
LS LD+L+L P PPV +LPLGTGNDLARTLNWGGGYTDEPVSKIL VE+G VVQLDRW+
Sbjct: 442 LSILDELQLSPQPPVGVLPLGTGNDLARTLNWGGGYTDEPVSKILCQVEDGTVVQLDRWN 501
Query: 422 LHAEPNPEAGPEDRDEGATDRLPLDVFNNYFSLGFDAHVTLEFHESREANPEKFNSRFRN 481
LH E NP+ PE+ ++G +LPL+VFNNYFSLGFDAHVTLEFHESREANPEKFNSRFRN
Sbjct: 502 LHVERNPDLPPEELEDGVC-KLPLNVFNNYFSLGFDAHVTLEFHESREANPEKFNSRFRN 560
Query: 482 KMFYAGTAFSDFLMGSSKDLAKHIRVVCDGMDLTPKIQDLKPQCVVFLNIPRYCAGTMPW 541
KMFYAG AFSDFL SS+DL+KH++VVCDG DLTPKIQ+LK QC+VFLNIPRYCAGTMPW
Sbjct: 561 KMFYAGAAFSDFLQRSSRDLSKHVKVVCDGTDLTPKIQELKFQCIVFLNIPRYCAGTMPW 620
Query: 542 GHPGEHHDFEPQRHDDGYLEVIGFTMTSLAALQVGGHGERLTQCREVVLTTSKAIPVQVD 601
G+PG+HHDFEPQRHDDGY+EVIGFTM SLAALQVGGHGERL QCREV+L T K+IP+QVD
Sbjct: 621 GNPGDHHDFEPQRHDDGYIEVIGFTMASLAALQVGGHGERLHQCREVMLLTYKSIPMQVD 680
Query: 602 GEPCKLAASRIRIALRNQATMVQKAKRRSAAPLHSDQQPVPEQLRIQVSRVSMHDYEALH 661
GEPC+LA + IRI+LRNQA MVQK+KRR++ PL +D Q VP++LRI+V+++S+ DYE H
Sbjct: 681 GEPCRLAPAMIRISLRNQANMVQKSKRRTSMPLLNDPQSVPDRLRIRVNKISLQDYEGFH 740
Query: 662 YDKEQLKEAS------------------VPLGTVVVPGDSDLELCRAHIERLQQEPDGAG 703
YDKE+L+EAS +PLG +VV GD DLE CR +I+RLQ++
Sbjct: 741 YDKEKLREASISDWLRTIAGELVQSFGAIPLGILVVRGDCDLETCRMYIDRLQEDLQSVS 800
Query: 704 AKSP---------------TCQKLSPKWCFLDATTASRFYRIDRAQEHLNYVTEIAQDEI 748
+ S + Q+LSP+WCFLD DR+QEHL++V EI+QDEI
Sbjct: 801 SGSQRVHYQDHETSFPRALSAQRLSPRWCFLD----------DRSQEHLHFVMEISQDEI 850
Query: 749 YILDPELLGAS------ARPDLPTPTSPLPTSPCSPTPR------SLQGDAAP------- 789
+ILDP+++ + PDL + + +P R S G AP
Sbjct: 851 FILDPDMVVSQPAGTPPGMPDLVVEQASGISDWWNPALRKRMLSDSGLGMIAPYYEDSDL 910
Query: 790 --------------PQGEELIEAAKRNDFCKLQELHRAGGDLMHRDEQSRTLLHHAVSTG 835
+ +++A D KL E ++ GG L+ + +LLH+A TG
Sbjct: 911 KDLSHSRVLQSPVSSEDHAILQAVIAGDLMKLIESYKNGGSLLIQGPDHCSLLHYAAKTG 970
Query: 836 SKDVVRYLLDHAPPEILD-AVEENGETCLHQAAALGQRTICHYIVEAGASLMKTDQQGDT 894
+ ++V+Y+LDH P E+LD A E GET LH+AA R +C +V+AGASL KTD +G T
Sbjct: 971 NGEIVKYILDHGPSELLDMADSETGETALHKAACQRNRAVCQLLVDAGASLRKTDSKGKT 1030
Query: 895 PRQRAEKAQDTELAAYLENRQHYQMIQREDQETAV 929
P++RA++A D +LAAYLE+RQ+Y++I ED ETAV
Sbjct: 1031 PQERAQQAGDPDLAAYLESRQNYKVIGHEDLETAV 1065
>gi|22027632 diacylglycerol kinase, beta isoform 1 [Homo sapiens]
Length = 804
Score = 293 bits (751), Expect = 4e-79
Identities = 188/573 (32%), Positives = 276/573 (48%), Gaps = 79/573 (13%)
Query: 96 GEHIWFETNVSGD-FCYVGEQYCVARMLQKSVSRRKCAACKIVVHTPCIEQLEKINFRCK 154
G+H+W + + +C + C+ ++ C+ CK VH C+ R
Sbjct: 243 GQHVWRLKHFNKPAYCNL----CLNMLIGVGKQGLCCSFCKYTVHERCVA-------RAP 291
Query: 155 PSFRESGSRNVREPTFVRHHWVHRRRQDGKCRHCGKGFQQKFTFHSKEIVAISCSWCKQA 214
PS ++ ++ R + H+WV KC C K + + + + C WC+
Sbjct: 292 PSCIKTYVKSKRNTDVMHHYWVEGNCPT-KCDKCHKTVKCY-----QGLTGLHCVWCQIT 345
Query: 215 YHSKVSCFMLQQIEEPCSLGVHAAVVIPPTWI---LRARRPQNTLKASKKKKRASFKRKS 271
H+K + ++ C G ++PPT I + P + + ++++ K KS
Sbjct: 346 LHNKCA----SHLKPECDCGPLKDHILPPTTICPVVLQTLPTSGVSVPEERQSTVKKEKS 401
Query: 272 SKKGPEEGRWRPFIIRP------------TPSPLMKPLLVFVNPKSGGNQGAKIIQSFLW 319
+ P + + + R TP P PLLVFVNPKSGG QG +I + F +
Sbjct: 402 GSQQPNKVIDKNKMQRANSVTVDGQGLQVTPVPGTHPLLVFVNPKSGGKQGERIYRKFQY 461
Query: 320 YLNPRQVFDLSQGGPKEALEMYRKVHNLRILACGGDGTVGWILSTLDQLRLKPPPPVAIL 379
LNPRQV+ LS GP L +R V + R+LACGGDGTVGW+L +++ + PPVAIL
Sbjct: 462 LLNPRQVYSLSGNGPMPGLNFFRDVPDFRVLACGGDGTVGWVLDCIEKANVGKHPPVAIL 521
Query: 380 PLGTGNDLARTLNWGGGYTDEPVSKILSHVEEGNVVQLDRWDLHAEPNPEAGPEDRDEGA 439
PLGTGNDLAR L WGGGY E + KIL +E + LDRW PN D+DE
Sbjct: 522 PLGTGNDLARCLRWGGGYEGENLMKILKDIENSTEIMLDRWKFEVIPN------DKDEKG 575
Query: 440 TDRLPLDVFNNYFSLGFDAHVTLEFHESREANPEKFNSRFRNKMFYAGTAFSDFLMGSSK 499
D +P + NNYFS+G DA + FH RE +PEKFNSR +NK +Y S+ + K
Sbjct: 576 -DPVPYSIINNYFSIGVDASIAHRFHIMREKHPEKFNSRMKNKFWYFEFGTSETFSATCK 634
Query: 500 DLAKHIRVVCDGMDLTPKIQDLKPQCVVFLNIPRYCAGTMPWGHPGEHHD---------- 549
L + + + CDG+ + + ++ + + LNIP G+ WG +
Sbjct: 635 KLHESVEIECDGVQI--DLINISLEGIAILNIPSMHGGSNLWGESKKRRSHRRIEKKGSD 692
Query: 550 ------------FEPQRHDDGYLEVIGFTMTSLAALQVG-------GHGERLTQCREVVL 590
F Q D LEV+G A+++G G RL QC VV+
Sbjct: 693 KRTTVTDAKELKFASQDLSDQLLEVVGLE----GAMEMGQIYTGLKSAGRRLAQCSCVVI 748
Query: 591 TTSKAIPVQVDGEPCKLAASRIRIALRNQATMV 623
TSK++P+Q+DGEP I+I +NQA M+
Sbjct: 749 RTSKSLPMQIDGEPWMQTPCTIKITHKNQAPML 781
>gi|124256476 diacylglycerol kinase gamma isoform 1 [Homo sapiens]
Length = 791
Score = 288 bits (737), Expect = 2e-77
Identities = 193/572 (33%), Positives = 274/572 (47%), Gaps = 80/572 (13%)
Query: 87 VDWSESATYGEHIW----FETNVSGDFCYVGEQYCVARMLQKSVSRRKCAACKIVVHTPC 142
+D S S G H W F+ +FC++ ++ C CK VH C
Sbjct: 261 MDDSGSKGDGRHAWTMKHFKKPTYCNFCHI-------MLMGVRKQGLCCTYCKYTVHERC 313
Query: 143 IEQLEKINFRCKPSFRESGSRNVREPTFVRHHWVHRRRQDGKCRHCGKGFQQKFTFHSKE 202
+ R P ++ S+ R ++H WV KC C K + +
Sbjct: 314 VS-------RNIPGCVKTYSKAKRSGEVMQHAWVEGN-SSVKCDRCHKSIKCY-----QS 360
Query: 203 IVAISCSWCKQAYHSKVSCFMLQQIEEPCSLGVHAAVVIPPTWILRARRPQNTLKASKKK 262
+ A C WC+ +H K ++ C G ++ PT I R + K+
Sbjct: 361 VTARHCVWCRMTFHRKC------ELSTLCDGGELRDHILLPTSICPITRDRPGEKSD--- 411
Query: 263 KRASFKRKSSKKGPEEGRWRPFIIRPTPSPLMKPLLVFVNPKSGGNQGAKIIQSFLWYLN 322
S KG +++ I PTP PLLV VNPKSGG QG +I++ F + LN
Sbjct: 412 ------GCVSAKGELVMQYK---IIPTPG--THPLLVLVNPKSGGRQGERILRKFHYLLN 460
Query: 323 PRQVFDLSQGGPKEALEMYRKVHNLRILACGGDGTVGWILSTLDQLRLKPPPPVAILPLG 382
P+QVF+L GGP L +R + R+LACGGDGTVGWIL +D+ PPVA+LPLG
Sbjct: 461 PKQVFNLDNGGPTPGLNFFRDTPDFRVLACGGDGTVGWILDCIDKANFAKHPPVAVLPLG 520
Query: 383 TGNDLARTLNWGGGYTDEPVSKILSHVEEGNVVQLDRWDLHAEPNPEAGPEDRDEGATDR 442
TGNDLAR L WGGGY ++KIL +E+ +V LDRW L P E+ + G D+
Sbjct: 521 TGNDLARCLRWGGGYEGGSLTKILKDIEQSPLVMLDRWHLEVIPR-----EEVENG--DQ 573
Query: 443 LPLDVFNNYFSLGFDAHVTLEFHESREANPEKFNSRFRNKMFYAGTAFSDFLMGSSKDLA 502
+P + NNYFS+G DA + FH RE +PEKFNSR +NK++Y S+ + K L
Sbjct: 574 VPYSIMNNYFSIGVDASIAHRFHVMREKHPEKFNSRMKNKLWYFEFGTSETFAATCKKLH 633
Query: 503 KHIRVVCDGMDLTPKIQDLKPQCVVFLNIPRYCAGTMPWGHPGEHH-------------- 548
HI + CDG+ + + ++ + + LNIP GT WG ++
Sbjct: 634 DHIELECDGVGV--DLSNIFLEGIAILNIPSMYGGTNLWGENKKNRAVIRESRKGVTDPK 691
Query: 549 --DFEPQRHDDGYLEVIGFTMTSLAALQVG-------GHGERLTQCREVVLTTSKAIPVQ 599
F Q D LEV+G A+++G G RL QC V + T+K +P+Q
Sbjct: 692 ELKFCVQDLSDQLLEVVGLE----GAMEMGQIYTGLKSAGRRLAQCASVTIRTNKLLPMQ 747
Query: 600 VDGEPCKLAASRIRIALRNQATMVQKAKRRSA 631
VDGEP I+I +NQA M+ ++S+
Sbjct: 748 VDGEPWMQPCCTIKITHKNQAPMMMGPPQKSS 779
>gi|22027634 diacylglycerol kinase, beta isoform 2 [Homo sapiens]
Length = 773
Score = 285 bits (730), Expect = 1e-76
Identities = 182/554 (32%), Positives = 267/554 (48%), Gaps = 79/554 (14%)
Query: 96 GEHIWFETNVSGD-FCYVGEQYCVARMLQKSVSRRKCAACKIVVHTPCIEQLEKINFRCK 154
G+H+W + + +C + C+ ++ C+ CK VH C+ R
Sbjct: 243 GQHVWRLKHFNKPAYCNL----CLNMLIGVGKQGLCCSFCKYTVHERCVA-------RAP 291
Query: 155 PSFRESGSRNVREPTFVRHHWVHRRRQDGKCRHCGKGFQQKFTFHSKEIVAISCSWCKQA 214
PS ++ ++ R + H+WV KC C K + + + + C WC+
Sbjct: 292 PSCIKTYVKSKRNTDVMHHYWVEGNCPT-KCDKCHKTVKCY-----QGLTGLHCVWCQIT 345
Query: 215 YHSKVSCFMLQQIEEPCSLGVHAAVVIPPTWI---LRARRPQNTLKASKKKKRASFKRKS 271
H+K + ++ C G ++PPT I + P + + ++++ K KS
Sbjct: 346 LHNKCA----SHLKPECDCGPLKDHILPPTTICPVVLQTLPTSGVSVPEERQSTVKKEKS 401
Query: 272 SKKGPEEGRWRPFIIRP------------TPSPLMKPLLVFVNPKSGGNQGAKIIQSFLW 319
+ P + + + R TP P PLLVFVNPKSGG QG +I + F +
Sbjct: 402 GSQQPNKVIDKNKMQRANSVTVDGQGLQVTPVPGTHPLLVFVNPKSGGKQGERIYRKFQY 461
Query: 320 YLNPRQVFDLSQGGPKEALEMYRKVHNLRILACGGDGTVGWILSTLDQLRLKPPPPVAIL 379
LNPRQV+ LS GP L +R V + R+LACGGDGTVGW+L +++ + PPVAIL
Sbjct: 462 LLNPRQVYSLSGNGPMPGLNFFRDVPDFRVLACGGDGTVGWVLDCIEKANVGKHPPVAIL 521
Query: 380 PLGTGNDLARTLNWGGGYTDEPVSKILSHVEEGNVVQLDRWDLHAEPNPEAGPEDRDEGA 439
PLGTGNDLAR L WGGGY E + KIL +E + LDRW PN D+DE
Sbjct: 522 PLGTGNDLARCLRWGGGYEGENLMKILKDIENSTEIMLDRWKFEVIPN------DKDEKG 575
Query: 440 TDRLPLDVFNNYFSLGFDAHVTLEFHESREANPEKFNSRFRNKMFYAGTAFSDFLMGSSK 499
D +P + NNYFS+G DA + FH RE +PEKFNSR +NK +Y S+ + K
Sbjct: 576 -DPVPYSIINNYFSIGVDASIAHRFHIMREKHPEKFNSRMKNKFWYFEFGTSETFSATCK 634
Query: 500 DLAKHIRVVCDGMDLTPKIQDLKPQCVVFLNIPRYCAGTMPWGHPGEHHD---------- 549
L + + + CDG+ + + ++ + + LNIP G+ WG +
Sbjct: 635 KLHESVEIECDGVQI--DLINISLEGIAILNIPSMHGGSNLWGESKKRRSHRRIEKKGSD 692
Query: 550 ------------FEPQRHDDGYLEVIGFTMTSLAALQVG-------GHGERLTQCREVVL 590
F Q D LEV+G A+++G G RL QC VV+
Sbjct: 693 KRTTVTDAKELKFASQDLSDQLLEVVGLE----GAMEMGQIYTGLKSAGRRLAQCSCVVI 748
Query: 591 TTSKAIPVQVDGEP 604
TSK++P+Q+DGEP
Sbjct: 749 RTSKSLPMQIDGEP 762
>gi|41872494 diacylglycerol kinase, alpha 80kDa [Homo sapiens]
Length = 735
Score = 279 bits (714), Expect = 8e-75
Identities = 185/569 (32%), Positives = 271/569 (47%), Gaps = 79/569 (13%)
Query: 96 GEHIWFETNVSGDFCYVGEQYCVARMLQKSVSRRK----CAACKIVVHTPCIEQLEKINF 151
G+H+W + YC + + S+ K C CK VH C
Sbjct: 204 GQHMWRPKR------FPRPVYC--NLCESSIGLGKQGLSCNLCKYTVHDQCA-------M 248
Query: 152 RCKPSFRESGSRNVREPTFVRHHWVHRRRQDGKCRHCGKGFQQKFTFHSKEIVAISCSWC 211
+ P + +++ ++ H WV + G+C C K + +HS + + C WC
Sbjct: 249 KALPCEVSTYAKSRKDIGVQSHVWVRGGCESGRCDRCQKKIR---IYHS--LTGLHCVWC 303
Query: 212 KQAYHSKVSCFMLQQIEEPCSLGVHAAVVIPPTWILRARRPQNTLKASKKKKRASFKRKS 271
H ++ LQ + C G+ ++PP+ I + L + +K + + S
Sbjct: 304 ----HLEIHDDCLQAVGHECDCGLLRDHILPPSSIY-----PSVLASGPDRKNS---KTS 351
Query: 272 SKKGPEEGRWRPFIIRPTPSPLMKPLLVFVNPKSGGNQGAKIIQSFLWYLNPRQVFDLSQ 331
K + +R P P PLLVFVNPKSGG QG +++ F + LNPRQVF+L +
Sbjct: 352 QKTMDDLNLSTSEALRIDPVPNTHPLLVFVNPKSGGKQGQRVLWKFQYILNPRQVFNLLK 411
Query: 332 GGPKEALEMYRKVHNLRILACGGDGTVGWILSTLDQLRLKPPPPVAILPLGTGNDLARTL 391
GP+ L +++ V + RIL CGGDGTVGWIL T+D+ L PPVA+LPLGTGNDLAR L
Sbjct: 412 DGPEIGLRLFKDVPDSRILVCGGDGTVGWILETIDKANLPVLPPVAVLPLGTGNDLARCL 471
Query: 392 NWGGGYTDEPVSKILSHVEEGNVVQLDRWDLHAEPNPEAGPEDRDEGATDRLPLDVFNNY 451
WGGGY + ++KIL +E VV +DRW + P + E +D +P + NNY
Sbjct: 472 RWGGGYEGQNLAKILKDLEMSKVVHMDRWSVEVIP-------QQTEEKSDPVPFQIINNY 524
Query: 452 FSLGFDAHVTLEFHESREANPEKFNSRFRNKMFYAGTAFSDFLMGSSKDLAKHIRVVCDG 511
FS+G DA + FH RE PEKFNSR +NK++Y A S+ + + K L + + V G
Sbjct: 525 FSIGVDASIAHRFHIMREKYPEKFNSRMKNKLWYFEFATSESIFSTCKKLEESLTVEICG 584
Query: 512 MDLTPKIQDLKPQCVVFLNIPRYCAGTMPWGHPGEHHD----------------FEPQ-- 553
L + +L + + LNIP G+ WG H +P
Sbjct: 585 KPL--DLSNLSLEGIAVLNIPSMHGGSNLWGDTRRPHGDIYGINQALGATAKVITDPDIL 642
Query: 554 -----RHDDGYLEVIGFTMTSLAALQVG-------GHGERLTQCREVVLTTSKAIPVQVD 601
D LEV+G A+++G G RL +C E+ T+K +P+Q+D
Sbjct: 643 KTCVPDLSDKRLEVVGLE----GAIEMGQIYTKLKNAGRRLAKCSEITFHTTKTLPMQID 698
Query: 602 GEPCKLAASRIRIALRNQATMVQKAKRRS 630
GEP I+I +NQ M+ RS
Sbjct: 699 GEPWMQTPCTIKITHKNQMPMLMGPPPRS 727
>gi|41393587 diacylglycerol kinase, alpha 80kDa [Homo sapiens]
Length = 735
Score = 279 bits (714), Expect = 8e-75
Identities = 185/569 (32%), Positives = 271/569 (47%), Gaps = 79/569 (13%)
Query: 96 GEHIWFETNVSGDFCYVGEQYCVARMLQKSVSRRK----CAACKIVVHTPCIEQLEKINF 151
G+H+W + YC + + S+ K C CK VH C
Sbjct: 204 GQHMWRPKR------FPRPVYC--NLCESSIGLGKQGLSCNLCKYTVHDQCA-------M 248
Query: 152 RCKPSFRESGSRNVREPTFVRHHWVHRRRQDGKCRHCGKGFQQKFTFHSKEIVAISCSWC 211
+ P + +++ ++ H WV + G+C C K + +HS + + C WC
Sbjct: 249 KALPCEVSTYAKSRKDIGVQSHVWVRGGCESGRCDRCQKKIR---IYHS--LTGLHCVWC 303
Query: 212 KQAYHSKVSCFMLQQIEEPCSLGVHAAVVIPPTWILRARRPQNTLKASKKKKRASFKRKS 271
H ++ LQ + C G+ ++PP+ I + L + +K + + S
Sbjct: 304 ----HLEIHDDCLQAVGHECDCGLLRDHILPPSSIY-----PSVLASGPDRKNS---KTS 351
Query: 272 SKKGPEEGRWRPFIIRPTPSPLMKPLLVFVNPKSGGNQGAKIIQSFLWYLNPRQVFDLSQ 331
K + +R P P PLLVFVNPKSGG QG +++ F + LNPRQVF+L +
Sbjct: 352 QKTMDDLNLSTSEALRIDPVPNTHPLLVFVNPKSGGKQGQRVLWKFQYILNPRQVFNLLK 411
Query: 332 GGPKEALEMYRKVHNLRILACGGDGTVGWILSTLDQLRLKPPPPVAILPLGTGNDLARTL 391
GP+ L +++ V + RIL CGGDGTVGWIL T+D+ L PPVA+LPLGTGNDLAR L
Sbjct: 412 DGPEIGLRLFKDVPDSRILVCGGDGTVGWILETIDKANLPVLPPVAVLPLGTGNDLARCL 471
Query: 392 NWGGGYTDEPVSKILSHVEEGNVVQLDRWDLHAEPNPEAGPEDRDEGATDRLPLDVFNNY 451
WGGGY + ++KIL +E VV +DRW + P + E +D +P + NNY
Sbjct: 472 RWGGGYEGQNLAKILKDLEMSKVVHMDRWSVEVIP-------QQTEEKSDPVPFQIINNY 524
Query: 452 FSLGFDAHVTLEFHESREANPEKFNSRFRNKMFYAGTAFSDFLMGSSKDLAKHIRVVCDG 511
FS+G DA + FH RE PEKFNSR +NK++Y A S+ + + K L + + V G
Sbjct: 525 FSIGVDASIAHRFHIMREKYPEKFNSRMKNKLWYFEFATSESIFSTCKKLEESLTVEICG 584
Query: 512 MDLTPKIQDLKPQCVVFLNIPRYCAGTMPWGHPGEHHD----------------FEPQ-- 553
L + +L + + LNIP G+ WG H +P
Sbjct: 585 KPL--DLSNLSLEGIAVLNIPSMHGGSNLWGDTRRPHGDIYGINQALGATAKVITDPDIL 642
Query: 554 -----RHDDGYLEVIGFTMTSLAALQVG-------GHGERLTQCREVVLTTSKAIPVQVD 601
D LEV+G A+++G G RL +C E+ T+K +P+Q+D
Sbjct: 643 KTCVPDLSDKRLEVVGLE----GAIEMGQIYTKLKNAGRRLAKCSEITFHTTKTLPMQID 698
Query: 602 GEPCKLAASRIRIALRNQATMVQKAKRRS 630
GEP I+I +NQ M+ RS
Sbjct: 699 GEPWMQTPCTIKITHKNQMPMLMGPPPRS 727
>gi|31542504 diacylglycerol kinase, alpha 80kDa [Homo sapiens]
Length = 735
Score = 279 bits (714), Expect = 8e-75
Identities = 185/569 (32%), Positives = 271/569 (47%), Gaps = 79/569 (13%)
Query: 96 GEHIWFETNVSGDFCYVGEQYCVARMLQKSVSRRK----CAACKIVVHTPCIEQLEKINF 151
G+H+W + YC + + S+ K C CK VH C
Sbjct: 204 GQHMWRPKR------FPRPVYC--NLCESSIGLGKQGLSCNLCKYTVHDQCA-------M 248
Query: 152 RCKPSFRESGSRNVREPTFVRHHWVHRRRQDGKCRHCGKGFQQKFTFHSKEIVAISCSWC 211
+ P + +++ ++ H WV + G+C C K + +HS + + C WC
Sbjct: 249 KALPCEVSTYAKSRKDIGVQSHVWVRGGCESGRCDRCQKKIR---IYHS--LTGLHCVWC 303
Query: 212 KQAYHSKVSCFMLQQIEEPCSLGVHAAVVIPPTWILRARRPQNTLKASKKKKRASFKRKS 271
H ++ LQ + C G+ ++PP+ I + L + +K + + S
Sbjct: 304 ----HLEIHDDCLQAVGHECDCGLLRDHILPPSSIY-----PSVLASGPDRKNS---KTS 351
Query: 272 SKKGPEEGRWRPFIIRPTPSPLMKPLLVFVNPKSGGNQGAKIIQSFLWYLNPRQVFDLSQ 331
K + +R P P PLLVFVNPKSGG QG +++ F + LNPRQVF+L +
Sbjct: 352 QKTMDDLNLSTSEALRIDPVPNTHPLLVFVNPKSGGKQGQRVLWKFQYILNPRQVFNLLK 411
Query: 332 GGPKEALEMYRKVHNLRILACGGDGTVGWILSTLDQLRLKPPPPVAILPLGTGNDLARTL 391
GP+ L +++ V + RIL CGGDGTVGWIL T+D+ L PPVA+LPLGTGNDLAR L
Sbjct: 412 DGPEIGLRLFKDVPDSRILVCGGDGTVGWILETIDKANLPVLPPVAVLPLGTGNDLARCL 471
Query: 392 NWGGGYTDEPVSKILSHVEEGNVVQLDRWDLHAEPNPEAGPEDRDEGATDRLPLDVFNNY 451
WGGGY + ++KIL +E VV +DRW + P + E +D +P + NNY
Sbjct: 472 RWGGGYEGQNLAKILKDLEMSKVVHMDRWSVEVIP-------QQTEEKSDPVPFQIINNY 524
Query: 452 FSLGFDAHVTLEFHESREANPEKFNSRFRNKMFYAGTAFSDFLMGSSKDLAKHIRVVCDG 511
FS+G DA + FH RE PEKFNSR +NK++Y A S+ + + K L + + V G
Sbjct: 525 FSIGVDASIAHRFHIMREKYPEKFNSRMKNKLWYFEFATSESIFSTCKKLEESLTVEICG 584
Query: 512 MDLTPKIQDLKPQCVVFLNIPRYCAGTMPWGHPGEHHD----------------FEPQ-- 553
L + +L + + LNIP G+ WG H +P
Sbjct: 585 KPL--DLSNLSLEGIAVLNIPSMHGGSNLWGDTRRPHGDIYGINQALGATAKVITDPDIL 642
Query: 554 -----RHDDGYLEVIGFTMTSLAALQVG-------GHGERLTQCREVVLTTSKAIPVQVD 601
D LEV+G A+++G G RL +C E+ T+K +P+Q+D
Sbjct: 643 KTCVPDLSDKRLEVVGLE----GAIEMGQIYTKLKNAGRRLAKCSEITFHTTKTLPMQID 698
Query: 602 GEPCKLAASRIRIALRNQATMVQKAKRRS 630
GEP I+I +NQ M+ RS
Sbjct: 699 GEPWMQTPCTIKITHKNQMPMLMGPPPRS 727
>gi|41872500 diacylglycerol kinase, alpha 80kDa [Homo sapiens]
Length = 735
Score = 279 bits (714), Expect = 8e-75
Identities = 185/569 (32%), Positives = 271/569 (47%), Gaps = 79/569 (13%)
Query: 96 GEHIWFETNVSGDFCYVGEQYCVARMLQKSVSRRK----CAACKIVVHTPCIEQLEKINF 151
G+H+W + YC + + S+ K C CK VH C
Sbjct: 204 GQHMWRPKR------FPRPVYC--NLCESSIGLGKQGLSCNLCKYTVHDQCA-------M 248
Query: 152 RCKPSFRESGSRNVREPTFVRHHWVHRRRQDGKCRHCGKGFQQKFTFHSKEIVAISCSWC 211
+ P + +++ ++ H WV + G+C C K + +HS + + C WC
Sbjct: 249 KALPCEVSTYAKSRKDIGVQSHVWVRGGCESGRCDRCQKKIR---IYHS--LTGLHCVWC 303
Query: 212 KQAYHSKVSCFMLQQIEEPCSLGVHAAVVIPPTWILRARRPQNTLKASKKKKRASFKRKS 271
H ++ LQ + C G+ ++PP+ I + L + +K + + S
Sbjct: 304 ----HLEIHDDCLQAVGHECDCGLLRDHILPPSSIY-----PSVLASGPDRKNS---KTS 351
Query: 272 SKKGPEEGRWRPFIIRPTPSPLMKPLLVFVNPKSGGNQGAKIIQSFLWYLNPRQVFDLSQ 331
K + +R P P PLLVFVNPKSGG QG +++ F + LNPRQVF+L +
Sbjct: 352 QKTMDDLNLSTSEALRIDPVPNTHPLLVFVNPKSGGKQGQRVLWKFQYILNPRQVFNLLK 411
Query: 332 GGPKEALEMYRKVHNLRILACGGDGTVGWILSTLDQLRLKPPPPVAILPLGTGNDLARTL 391
GP+ L +++ V + RIL CGGDGTVGWIL T+D+ L PPVA+LPLGTGNDLAR L
Sbjct: 412 DGPEIGLRLFKDVPDSRILVCGGDGTVGWILETIDKANLPVLPPVAVLPLGTGNDLARCL 471
Query: 392 NWGGGYTDEPVSKILSHVEEGNVVQLDRWDLHAEPNPEAGPEDRDEGATDRLPLDVFNNY 451
WGGGY + ++KIL +E VV +DRW + P + E +D +P + NNY
Sbjct: 472 RWGGGYEGQNLAKILKDLEMSKVVHMDRWSVEVIP-------QQTEEKSDPVPFQIINNY 524
Query: 452 FSLGFDAHVTLEFHESREANPEKFNSRFRNKMFYAGTAFSDFLMGSSKDLAKHIRVVCDG 511
FS+G DA + FH RE PEKFNSR +NK++Y A S+ + + K L + + V G
Sbjct: 525 FSIGVDASIAHRFHIMREKYPEKFNSRMKNKLWYFEFATSESIFSTCKKLEESLTVEICG 584
Query: 512 MDLTPKIQDLKPQCVVFLNIPRYCAGTMPWGHPGEHHD----------------FEPQ-- 553
L + +L + + LNIP G+ WG H +P
Sbjct: 585 KPL--DLSNLSLEGIAVLNIPSMHGGSNLWGDTRRPHGDIYGINQALGATAKVITDPDIL 642
Query: 554 -----RHDDGYLEVIGFTMTSLAALQVG-------GHGERLTQCREVVLTTSKAIPVQVD 601
D LEV+G A+++G G RL +C E+ T+K +P+Q+D
Sbjct: 643 KTCVPDLSDKRLEVVGLE----GAIEMGQIYTKLKNAGRRLAKCSEITFHTTKTLPMQID 698
Query: 602 GEPCKLAASRIRIALRNQATMVQKAKRRS 630
GEP I+I +NQ M+ RS
Sbjct: 699 GEPWMQTPCTIKITHKNQMPMLMGPPPRS 727
>gi|124256482 diacylglycerol kinase gamma isoform 3 [Homo sapiens]
Length = 752
Score = 270 bits (689), Expect = 6e-72
Identities = 149/365 (40%), Positives = 204/365 (55%), Gaps = 36/365 (9%)
Query: 290 PSPLMKPLLVFVNPKSGGNQGAKIIQSFLWYLNPRQVFDLSQGGPKEALEMYRKVHNLRI 349
P+P PLLV VNPKSGG QG +I++ F + LNP+QVF+L GGP L +R + R+
Sbjct: 389 PTPGTHPLLVLVNPKSGGRQGERILRKFHYLLNPKQVFNLDNGGPTPGLNFFRDTPDFRV 448
Query: 350 LACGGDGTVGWILSTLDQLRLKPPPPVAILPLGTGNDLARTLNWGGGYTDEPVSKILSHV 409
LACGGDGTVGWIL +D+ PPVA+LPLGTGNDLAR L WGGGY ++KIL +
Sbjct: 449 LACGGDGTVGWILDCIDKANFAKHPPVAVLPLGTGNDLARCLRWGGGYEGGSLTKILKDI 508
Query: 410 EEGNVVQLDRWDLHAEPNPEAGPEDRDEGATDRLPLDVFNNYFSLGFDAHVTLEFHESRE 469
E+ +V LDRW L P E+ + G D++P + NNYFS+G DA + FH RE
Sbjct: 509 EQSPLVMLDRWHLEVIPR-----EEVENG--DQVPYSIMNNYFSIGVDASIAHRFHVMRE 561
Query: 470 ANPEKFNSRFRNKMFYAGTAFSDFLMGSSKDLAKHIRVVCDGMDLTPKIQDLKPQCVVFL 529
+PEKFNSR +NK++Y S+ + K L HI + CDG+ + + ++ + + L
Sbjct: 562 KHPEKFNSRMKNKLWYFEFGTSETFAATCKKLHDHIELECDGVGV--DLSNIFLEGIAIL 619
Query: 530 NIPRYCAGTMPWGHPGEHH----------------DFEPQRHDDGYLEVIGFTMTSLAAL 573
NIP GT WG ++ F Q D LEV+G A+
Sbjct: 620 NIPSMYGGTNLWGENKKNRAVIRESRKGVTDPKELKFCVQDLSDQLLEVVGLE----GAM 675
Query: 574 QVG-------GHGERLTQCREVVLTTSKAIPVQVDGEPCKLAASRIRIALRNQATMVQKA 626
++G G RL QC V + T+K +P+QVDGEP I+I +NQA M+
Sbjct: 676 EMGQIYTGLKSAGRRLAQCASVTIRTNKLLPMQVDGEPWMQPCCTIKITHKNQAPMMMGP 735
Query: 627 KRRSA 631
++S+
Sbjct: 736 PQKSS 740
>gi|124256474 diacylglycerol kinase gamma isoform 2 [Homo sapiens]
Length = 766
Score = 249 bits (637), Expect = 6e-66
Identities = 182/572 (31%), Positives = 257/572 (44%), Gaps = 105/572 (18%)
Query: 87 VDWSESATYGEHIW----FETNVSGDFCYVGEQYCVARMLQKSVSRRKCAACKIVVHTPC 142
+D S S G H W F+ +FC++ ++ C CK VH C
Sbjct: 261 MDDSGSKGDGRHAWTMKHFKKPTYCNFCHI-------MLMGVRKQGLCCTYCKYTVHERC 313
Query: 143 IEQLEKINFRCKPSFRESGSRNVREPTFVRHHWVHRRRQDGKCRHCGKGFQQKFTFHSKE 202
+ R P ++ S+ R ++H WV KC C K + +
Sbjct: 314 VS-------RNIPGCVKTYSKAKRSGEVMQHAWVEGN-SSVKCDRCHKSIKCY-----QS 360
Query: 203 IVAISCSWCKQAYHSKVSCFMLQQIEEPCSLGVHAAVVIPPTWILRARRPQNTLKASKKK 262
+ A C WC+ +H K ++ C G ++ PT I R + K+
Sbjct: 361 VTARHCVWCRMTFHRKC------ELSTLCDGGELRDHILLPTSICPITRDRPGEKSD--- 411
Query: 263 KRASFKRKSSKKGPEEGRWRPFIIRPTPSPLMKPLLVFVNPKSGGNQGAKIIQSFLWYLN 322
S KG +++ I PTP PLLV VNPKSGG QG
Sbjct: 412 ------GCVSAKGELVMQYK---IIPTPG--THPLLVLVNPKSGGRQG------------ 448
Query: 323 PRQVFDLSQGGPKEALEMYRKVHNLRILACGGDGTVGWILSTLDQLRLKPPPPVAILPLG 382
E L +R + R+LACGGDGTVGWIL +D+ PPVA+LPLG
Sbjct: 449 -------------ERLNFFRDTPDFRVLACGGDGTVGWILDCIDKANFAKHPPVAVLPLG 495
Query: 383 TGNDLARTLNWGGGYTDEPVSKILSHVEEGNVVQLDRWDLHAEPNPEAGPEDRDEGATDR 442
TGNDLAR L WGGGY ++KIL +E+ +V LDRW L P E+ + G D+
Sbjct: 496 TGNDLARCLRWGGGYEGGSLTKILKDIEQSPLVMLDRWHLEVIPR-----EEVENG--DQ 548
Query: 443 LPLDVFNNYFSLGFDAHVTLEFHESREANPEKFNSRFRNKMFYAGTAFSDFLMGSSKDLA 502
+P + NNYFS+G DA + FH RE +PEKFNSR +NK++Y S+ + K L
Sbjct: 549 VPYSIMNNYFSIGVDASIAHRFHVMREKHPEKFNSRMKNKLWYFEFGTSETFAATCKKLH 608
Query: 503 KHIRVVCDGMDLTPKIQDLKPQCVVFLNIPRYCAGTMPWGHPGEHH-------------- 548
HI + CDG+ + + ++ + + LNIP GT WG ++
Sbjct: 609 DHIELECDGVGV--DLSNIFLEGIAILNIPSMYGGTNLWGENKKNRAVIRESRKGVTDPK 666
Query: 549 --DFEPQRHDDGYLEVIGFTMTSLAALQVG-------GHGERLTQCREVVLTTSKAIPVQ 599
F Q D LEV+G A+++G G RL QC V + T+K +P+Q
Sbjct: 667 ELKFCVQDLSDQLLEVVGLE----GAMEMGQIYTGLKSAGRRLAQCASVTIRTNKLLPMQ 722
Query: 600 VDGEPCKLAASRIRIALRNQATMVQKAKRRSA 631
VDGEP I+I +NQA M+ ++S+
Sbjct: 723 VDGEPWMQPCCTIKITHKNQAPMMMGPPQKSS 754
>gi|40806175 diacylglycerol kinase, theta [Homo sapiens]
Length = 942
Score = 238 bits (606), Expect = 3e-62
Identities = 147/373 (39%), Positives = 205/373 (54%), Gaps = 21/373 (5%)
Query: 283 PFIIRPTPSPLMKPLLVFVNPKSGGNQGAKIIQSFLWYLNPRQVFDLSQGGPKEALEMYR 342
P ++ P PLLVFVNPKSGG +G ++ SF LNP QVFDL+ GGP L ++
Sbjct: 575 PDLLHAKLPPDSCPLLVFVNPKSGGLKGRDLLCSFRKLLNPHQVFDLTNGGPLPGLHLFS 634
Query: 343 KVHNLRILACGGDGTVGWILSTLDQLRLK---PPPPVAILPLGTGNDLARTLNWGGGYTD 399
+V R+L CGGDGTVGW+L L++ R + P P VAILPLGTGNDL R L WG GY+
Sbjct: 635 QVPCFRVLVCGGDGTVGWVLGALEETRYRLACPEPSVAILPLGTGNDLGRVLRWGAGYSG 694
Query: 400 EPVSKILSHVEEGNVVQLDRWDLHAEPNPEAGPEDRDEGATDRLPLDVFNNYFSLGFDAH 459
E +L V+E + V +DRW + + + EAG + D + + +NY +G DA
Sbjct: 695 EDPFSVLLSVDEADAVLMDRWTILLDAH-EAGSAENDTADAEPPKIVQMSNYCGIGIDAE 753
Query: 460 VTLEFHESREANPEKFNSRFRNKMFYAGTAFSDFLMGSSKDLAKHIRVVCDGMDL-TPKI 518
++L+FH++RE P KF SR NK Y + S+ L K IR+ + ++ P I
Sbjct: 754 LSLDFHQAREEEPGKFTSRLHNKGVYVRVGLQK--ISHSRSLHKQIRLQVERQEVELPSI 811
Query: 519 QDLKPQCVVFLNIPRYCAGTMPWGHPGEHHDFEPQRHDDGYLEVIGFT-MTSLAALQVG- 576
+ L +F+NIP + +G WG + FE R DDG LEV+G T + + +Q G
Sbjct: 812 EGL-----IFINIPSWGSGADLWGSDSDTR-FEKPRMDDGLLEVVGVTGVVHMGQVQGGL 865
Query: 577 GHGERLTQCREVVLTTSKAIPVQVDGEPCKLAASRIRI-ALRNQATMVQKAKRR-----S 630
G R+ Q +T KA PVQVDGEP A + I A + M++KAK++ +
Sbjct: 866 RSGIRIAQGSYFRVTLLKATPVQVDGEPWVQAPGHMIISAAGPKVHMLRKAKQKPRRAGT 925
Query: 631 AAPLHSDQQPVPE 643
+D P PE
Sbjct: 926 TRDARADAAPAPE 938
>gi|4503313 diacylglycerol kinase epsilon [Homo sapiens]
Length = 567
Score = 217 bits (553), Expect = 4e-56
Identities = 164/542 (30%), Positives = 262/542 (48%), Gaps = 72/542 (13%)
Query: 97 EHIWFETNVSGD--FCYVGEQYCVARMLQKSVSRRKCAACKIVVHTPCIEQLEKINFRCK 154
+H W +T++ +C V C +LQ + C C + V C+ + +K F+CK
Sbjct: 59 KHGWRDTDLFSQPTYCCV----CAQHILQGAF----CDCCGLRVDEGCLRKADK-RFQCK 109
Query: 155 PSFRESGSRNVREPTFVRHHWVHRRRQDGKCRHCGKGFQQKFTFHSKEIVAISCSWCKQA 214
++ ++ + + HHW+ R C +C QQ ++ C WC++
Sbjct: 110 EIMLKNDTKVLDA---MPHHWI--RGNVPLCSYCMVCKQQCGC--QPKLCDYRCIWCQKT 162
Query: 215 YHSKVSCFMLQQIEEPCSLGVHAAVVIPPTWILRARRPQNTLKASKKKKRASFKRKSSKK 274
H + C E C G ++IPP+++ ++ +K K+ ++ +SK
Sbjct: 163 VHDE--CMKNSLKNEKCDFGEFKNLIIPPSYL-------TSINQMRKDKKTDYEVLASKL 213
Query: 275 GPEEGRWRPFIIRPTPSPLMKPLLVFVNPKSGGNQGAKIIQSFLWYLNPRQVFDLSQGGP 334
G + W P L++ N +SG N G ++ F LNP QVFD+++ P
Sbjct: 214 GKQ---WTP-------------LIILANSRSGTNMGEGLLGEFRILLNPVQVFDVTKTPP 257
Query: 335 KEALEMYRKV--HNLRILACGGDGTVGWILSTLDQLRLKPP----PPVAILPLGTGNDLA 388
+AL++ + ++ R+L CGGDGTVGW+L +D +++K P VA+LPLGTGNDL+
Sbjct: 258 IKALQLCTLLPYYSARVLVCGGDGTVGWVLDAVDDMKIKGQEKYIPQVAVLPLGTGNDLS 317
Query: 389 RTLNWGGGYTDE-PVSKILSHVEEGNVVQLDRWDLHAEPNPEAGPEDRDEGATD-RLPLD 446
TL WG GY E PV+++L +V E + ++LDRW + ++G + R P +
Sbjct: 318 NTLGWGTGYAGEIPVAQVLRNVMEADGIKLDRWKVQVT----------NKGYYNLRKPKE 367
Query: 447 -VFNNYFSLGFDAHVTLEFHESREANPEKFNSRFRNKMFYAGTAFSDFLMGSSKDLAKHI 505
NNYFS+G DA + L FH RE P F+SR NK Y D L+ KDL K +
Sbjct: 368 FTMNNYFSVGPDALMALNFHAHREKAPSLFSSRILNKAVYLFYGTKDCLVQECKDLNKKV 427
Query: 506 RVVCDGMDLT-PKIQDLKPQCVVFLNIPRYCAGTMPWGHPGEHHDFEPQRHDDGYLEVIG 564
+ DG + P ++ ++ LNI + G W G+ + RHDDG LEV+G
Sbjct: 428 ELELDGERVALPSLEG-----IIVLNIGYWGGGCRLWEGMGD-ETYPLARHDDGLLEVVG 481
Query: 565 -FTMTSLAALQVG-GHGERLTQCREV-VLTTSKAIPVQVDGEPCKLAASRIRIALRNQAT 621
+ A +QV + R+ Q V ++ +P+QVDGEP + I + A
Sbjct: 482 VYGSFHCAQIQVKLANPFRIGQAHTVRLILKCSMMPMQVDGEPWAQGPCTVTITHKTHAM 541
Query: 622 MV 623
M+
Sbjct: 542 ML 543
>gi|29788760 diacylglycerol kinase, eta isoform 1 [Homo sapiens]
Length = 1164
Score = 152 bits (384), Expect = 1e-36
Identities = 108/334 (32%), Positives = 146/334 (43%), Gaps = 55/334 (16%)
Query: 96 GEHIWFE-TNVSGDFCYVGEQYCVARMLQKSVSRRKCAACKIVVHTPCIEQLEKINFRCK 154
G H W+ ++ FC V C + + C CK H C + CK
Sbjct: 174 GMHNWYACSHARPTFCNV----CRESLSGVTSHGLSCEVCKFKAHKRCAVRATN---NCK 226
Query: 155 PSFRESGSRNVREP---TFVRHHWVHRRRQ-DGKCRHCGKGFQQKFTFHSKEIVAISCSW 210
+ S +++ E + H W+ KC C K + C W
Sbjct: 227 WTTLASIGKDIIEDEDGVAMPHQWLEGNLPVSAKCAVCDKTCGSVLRLQDWK-----CLW 281
Query: 211 CKQAYHSKVSCFMLQQIEEP-CSLGVHAAVVIPPTWILRARRPQNTLKASKKKKRASFKR 269
CK H+ +C + + P C LG +IPP +
Sbjct: 282 CKTMVHT--AC---KDLYHPICPLGQCKVSIIPPIAL----------------------N 314
Query: 270 KSSKKGPEEGRWRPFIIRPTPSPLMKPLLVFVNPKSGGNQGAKIIQSFLWYLNPRQVFDL 329
+ G R T S + PLLVFVN KSG NQG K ++ F LNP QVFDL
Sbjct: 315 STDSDG---------FCRATFSFCVSPLLVFVNSKSGDNQGVKFLRRFKQLLNPAQVFDL 365
Query: 330 SQGGPKEALEMYRKVHNLRILACGGDGTVGWILSTLDQLRLKPPPPVAILPLGTGNDLAR 389
GGP L +++K N RIL CGGDG+VGW+LS +D+L L + +LPLGTGNDLAR
Sbjct: 366 MNGGPHLGLRLFQKFDNFRILVCGGDGSVGWVLSEIDKLNLNKQCQLGVLPLGTGNDLAR 425
Query: 390 TLNWGGGYTDE-PVSKILSHVEEGNVVQLDRWDL 422
L WGG Y D+ + +IL +E + LDRW +
Sbjct: 426 VLGWGGSYDDDTQLPQILEKLERASTKMLDRWSI 459
Score = 105 bits (262), Expect = 2e-22
Identities = 65/184 (35%), Positives = 94/184 (51%), Gaps = 10/184 (5%)
Query: 447 VFNNYFSLGFDAHVTLEFHESREANPEKFNSRFRNKMFYAGTAFSDFLMGSSKDLAKHIR 506
V NNYF +G DA ++LEF+ RE +PEK SR +N M+Y + L S K+L + ++
Sbjct: 770 VMNNYFGIGLDAKISLEFNNKREEHPEKCRSRTKNLMWYGVLGTRELLQRSYKNLEQRVQ 829
Query: 507 VVCDGMDL-TPKIQDLKPQCVVFLNIPRYCAGTMPWGHPGEHHDFEPQRHDDGYLEVIGF 565
+ CDG + P +Q + LNIP Y GT WG E F DD LEV+
Sbjct: 830 LECDGQYIPLPSLQG-----IAVLNIPSYAGGTNFWGGTKEDDIFAAPSFDDKILEVVAI 884
Query: 566 --TMTSLAALQVGGHGERLTQCREVVLTT--SKAIPVQVDGEPCKLAASRIRIALRNQAT 621
+M + + R+ QCR V +T + +PVQVDGE I+I +N+A
Sbjct: 885 FDSMQMAVSRVIKLQHHRIAQCRTVKITIFGDEGVPVQVDGEAWVQPPGIIKIVHKNRAQ 944
Query: 622 MVQK 625
M+ +
Sbjct: 945 MLTR 948
>gi|29788751 diacylglycerol kinase, eta isoform 2 [Homo sapiens]
Length = 1220
Score = 152 bits (384), Expect = 1e-36
Identities = 108/334 (32%), Positives = 146/334 (43%), Gaps = 55/334 (16%)
Query: 96 GEHIWFE-TNVSGDFCYVGEQYCVARMLQKSVSRRKCAACKIVVHTPCIEQLEKINFRCK 154
G H W+ ++ FC V C + + C CK H C + CK
Sbjct: 174 GMHNWYACSHARPTFCNV----CRESLSGVTSHGLSCEVCKFKAHKRCAVRATN---NCK 226
Query: 155 PSFRESGSRNVREP---TFVRHHWVHRRRQ-DGKCRHCGKGFQQKFTFHSKEIVAISCSW 210
+ S +++ E + H W+ KC C K + C W
Sbjct: 227 WTTLASIGKDIIEDEDGVAMPHQWLEGNLPVSAKCAVCDKTCGSVLRLQDWK-----CLW 281
Query: 211 CKQAYHSKVSCFMLQQIEEP-CSLGVHAAVVIPPTWILRARRPQNTLKASKKKKRASFKR 269
CK H+ +C + + P C LG +IPP +
Sbjct: 282 CKTMVHT--AC---KDLYHPICPLGQCKVSIIPPIAL----------------------N 314
Query: 270 KSSKKGPEEGRWRPFIIRPTPSPLMKPLLVFVNPKSGGNQGAKIIQSFLWYLNPRQVFDL 329
+ G R T S + PLLVFVN KSG NQG K ++ F LNP QVFDL
Sbjct: 315 STDSDG---------FCRATFSFCVSPLLVFVNSKSGDNQGVKFLRRFKQLLNPAQVFDL 365
Query: 330 SQGGPKEALEMYRKVHNLRILACGGDGTVGWILSTLDQLRLKPPPPVAILPLGTGNDLAR 389
GGP L +++K N RIL CGGDG+VGW+LS +D+L L + +LPLGTGNDLAR
Sbjct: 366 MNGGPHLGLRLFQKFDNFRILVCGGDGSVGWVLSEIDKLNLNKQCQLGVLPLGTGNDLAR 425
Query: 390 TLNWGGGYTDE-PVSKILSHVEEGNVVQLDRWDL 422
L WGG Y D+ + +IL +E + LDRW +
Sbjct: 426 VLGWGGSYDDDTQLPQILEKLERASTKMLDRWSI 459
Score = 105 bits (262), Expect = 2e-22
Identities = 65/184 (35%), Positives = 94/184 (51%), Gaps = 10/184 (5%)
Query: 447 VFNNYFSLGFDAHVTLEFHESREANPEKFNSRFRNKMFYAGTAFSDFLMGSSKDLAKHIR 506
V NNYF +G DA ++LEF+ RE +PEK SR +N M+Y + L S K+L + ++
Sbjct: 770 VMNNYFGIGLDAKISLEFNNKREEHPEKCRSRTKNLMWYGVLGTRELLQRSYKNLEQRVQ 829
Query: 507 VVCDGMDL-TPKIQDLKPQCVVFLNIPRYCAGTMPWGHPGEHHDFEPQRHDDGYLEVIGF 565
+ CDG + P +Q + LNIP Y GT WG E F DD LEV+
Sbjct: 830 LECDGQYIPLPSLQG-----IAVLNIPSYAGGTNFWGGTKEDDIFAAPSFDDKILEVVAI 884
Query: 566 --TMTSLAALQVGGHGERLTQCREVVLTT--SKAIPVQVDGEPCKLAASRIRIALRNQAT 621
+M + + R+ QCR V +T + +PVQVDGE I+I +N+A
Sbjct: 885 FDSMQMAVSRVIKLQHHRIAQCRTVKITIFGDEGVPVQVDGEAWVQPPGIIKIVHKNRAQ 944
Query: 622 MVQK 625
M+ +
Sbjct: 945 MLTR 948
>gi|25777596 diacylglycerol kinase, delta 130kDa isoform 1 [Homo
sapiens]
Length = 1170
Score = 151 bits (381), Expect = 3e-36
Identities = 108/337 (32%), Positives = 145/337 (43%), Gaps = 56/337 (16%)
Query: 96 GEHIWFETNVSGDFCYVGEQYC-VARMLQKSVSRR--KCAACKIVVHTPCIEQLEKINFR 152
G H W+ + + YC V R V+ C CK H C +
Sbjct: 118 GMHNWYACS------HARPTYCNVCREALSGVTSHGLSCEVCKFKAHKRCAVRATN---N 168
Query: 153 CKPSFRESGSRNVREPT---FVRHHWVHRRRQ-DGKCRHCGKGFQQKFTFHSKEIVAISC 208
CK + S +++ E + H W+ KC C K C
Sbjct: 169 CKWTTLASIGKDIIEDADGIAMPHQWLEGNLPVSAKCTVCDKTCGSVLRLQDWR-----C 223
Query: 209 SWCKQAYHSKVSCFMLQQIEEPCSLGVHAAVVIPPTWILRARRPQNTLKASKKKKRASFK 268
WCK H+ +L + C LG+ VIPPT + N++ +
Sbjct: 224 LWCKAMVHTSCKESLLTK----CPLGLCKVSVIPPTAL-------NSIDS---------- 262
Query: 269 RKSSKKGPEEGRWRPFIIRPTPSPLMKPLLVFVNPKSGGNQGAKIIQSFLWYLNPRQVFD 328
+G W+ P PLLVFVN KSG NQG K ++ F LNP QVFD
Sbjct: 263 ---------DGFWKA----SCPPSCTSPLLVFVNSKSGDNQGVKFLRRFKQLLNPAQVFD 309
Query: 329 LSQGGPKEALEMYRKVHNLRILACGGDGTVGWILSTLDQLRLKPPPPVAILPLGTGNDLA 388
L GGP L +++K RIL CGGDG+VGW+LS +D L L + +LPLGTGNDLA
Sbjct: 310 LMNGGPHLGLRLFQKFDTFRILVCGGDGSVGWVLSEIDSLNLHKQCQLGVLPLGTGNDLA 369
Query: 389 RTLNWGGGYTDE-PVSKILSHVEEGNVVQLDRWDLHA 424
R L WG D+ + +IL +E + LDRW + A
Sbjct: 370 RVLGWGSACDDDTQLPQILEKLERASTKMLDRWSVMA 406
Score = 99.4 bits (246), Expect = 1e-20
Identities = 78/279 (27%), Positives = 124/279 (44%), Gaps = 25/279 (8%)
Query: 447 VFNNYFSLGFDAHVTLEFHESREANPEKFNSRFRNKMFYAGTAFSDFLMGSSKDLAKHIR 506
V NNYF +G DA ++L+F+ R+ +PEK SR +N M+Y + L + K+L + +
Sbjct: 719 VMNNYFGIGLDAKISLDFNNKRDEHPEKCRSRTKNMMWYGVLGTKELLHRTYKNLEQKVL 778
Query: 507 VVCDGMDL-TPKIQDLKPQCVVFLNIPRYCAGTMPWGHPGEHHDFEPQRHDDGYLEVIGF 565
+ CDG + P +Q + LNIP Y GT WG E F DD LEV+
Sbjct: 779 LECDGRPIPLPSLQG-----IAVLNIPSYAGGTNFWGGTKEDDTFAAPSFDDKILEVVAV 833
Query: 566 --TMTSLAALQVGGHGERLTQCREVVLTT--SKAIPVQVDGEPCKLAASRIRIALRNQA- 620
+M + + R+ QCR V ++ + +PVQVDGE IRI +N+A
Sbjct: 834 FGSMQMAVSRVIRLQHHRIAQCRTVKISILGDEGVPVQVDGEAWVQPPGYIRIVHKNRAQ 893
Query: 621 TMVQKAKRRSAAPLHSDQQ----PVPEQLRIQVSRVSMHDYEALHYDKEQLKEASVPLGT 676
T+ + S D+Q P P S+H + Q+ + G
Sbjct: 894 TLTRDRAFESTLKSWEDKQKCELPRPPS-------CSLHPEMLSEEEATQMDQFGQAAGV 946
Query: 677 VVVPGDSDLELCRAHIERLQQEPDGAGAKSPTCQKLSPK 715
++ S E+ ++H + Q+ A S + ++ K
Sbjct: 947 LI---HSIREIAQSHRDMEQELAHAVNASSKSMDRVYGK 982
>gi|25777598 diacylglycerol kinase, delta 130kDa isoform 2 [Homo
sapiens]
Length = 1214
Score = 151 bits (381), Expect = 3e-36
Identities = 108/337 (32%), Positives = 145/337 (43%), Gaps = 56/337 (16%)
Query: 96 GEHIWFETNVSGDFCYVGEQYC-VARMLQKSVSRR--KCAACKIVVHTPCIEQLEKINFR 152
G H W+ + + YC V R V+ C CK H C +
Sbjct: 162 GMHNWYACS------HARPTYCNVCREALSGVTSHGLSCEVCKFKAHKRCAVRATN---N 212
Query: 153 CKPSFRESGSRNVREPT---FVRHHWVHRRRQ-DGKCRHCGKGFQQKFTFHSKEIVAISC 208
CK + S +++ E + H W+ KC C K C
Sbjct: 213 CKWTTLASIGKDIIEDADGIAMPHQWLEGNLPVSAKCTVCDKTCGSVLRLQDWR-----C 267
Query: 209 SWCKQAYHSKVSCFMLQQIEEPCSLGVHAAVVIPPTWILRARRPQNTLKASKKKKRASFK 268
WCK H+ +L + C LG+ VIPPT + N++ +
Sbjct: 268 LWCKAMVHTSCKESLLTK----CPLGLCKVSVIPPTAL-------NSIDS---------- 306
Query: 269 RKSSKKGPEEGRWRPFIIRPTPSPLMKPLLVFVNPKSGGNQGAKIIQSFLWYLNPRQVFD 328
+G W+ P PLLVFVN KSG NQG K ++ F LNP QVFD
Sbjct: 307 ---------DGFWKA----SCPPSCTSPLLVFVNSKSGDNQGVKFLRRFKQLLNPAQVFD 353
Query: 329 LSQGGPKEALEMYRKVHNLRILACGGDGTVGWILSTLDQLRLKPPPPVAILPLGTGNDLA 388
L GGP L +++K RIL CGGDG+VGW+LS +D L L + +LPLGTGNDLA
Sbjct: 354 LMNGGPHLGLRLFQKFDTFRILVCGGDGSVGWVLSEIDSLNLHKQCQLGVLPLGTGNDLA 413
Query: 389 RTLNWGGGYTDE-PVSKILSHVEEGNVVQLDRWDLHA 424
R L WG D+ + +IL +E + LDRW + A
Sbjct: 414 RVLGWGSACDDDTQLPQILEKLERASTKMLDRWSVMA 450
Score = 99.4 bits (246), Expect = 1e-20
Identities = 78/279 (27%), Positives = 124/279 (44%), Gaps = 25/279 (8%)
Query: 447 VFNNYFSLGFDAHVTLEFHESREANPEKFNSRFRNKMFYAGTAFSDFLMGSSKDLAKHIR 506
V NNYF +G DA ++L+F+ R+ +PEK SR +N M+Y + L + K+L + +
Sbjct: 763 VMNNYFGIGLDAKISLDFNNKRDEHPEKCRSRTKNMMWYGVLGTKELLHRTYKNLEQKVL 822
Query: 507 VVCDGMDL-TPKIQDLKPQCVVFLNIPRYCAGTMPWGHPGEHHDFEPQRHDDGYLEVIGF 565
+ CDG + P +Q + LNIP Y GT WG E F DD LEV+
Sbjct: 823 LECDGRPIPLPSLQG-----IAVLNIPSYAGGTNFWGGTKEDDTFAAPSFDDKILEVVAV 877
Query: 566 --TMTSLAALQVGGHGERLTQCREVVLTT--SKAIPVQVDGEPCKLAASRIRIALRNQA- 620
+M + + R+ QCR V ++ + +PVQVDGE IRI +N+A
Sbjct: 878 FGSMQMAVSRVIRLQHHRIAQCRTVKISILGDEGVPVQVDGEAWVQPPGYIRIVHKNRAQ 937
Query: 621 TMVQKAKRRSAAPLHSDQQ----PVPEQLRIQVSRVSMHDYEALHYDKEQLKEASVPLGT 676
T+ + S D+Q P P S+H + Q+ + G
Sbjct: 938 TLTRDRAFESTLKSWEDKQKCELPRPPS-------CSLHPEMLSEEEATQMDQFGQAAGV 990
Query: 677 VVVPGDSDLELCRAHIERLQQEPDGAGAKSPTCQKLSPK 715
++ S E+ ++H + Q+ A S + ++ K
Sbjct: 991 LI---HSIREIAQSHRDMEQELAHAVNASSKSMDRVYGK 1026
>gi|62000702 diacylglycerol kinase kappa [Homo sapiens]
Length = 1271
Score = 134 bits (337), Expect = 4e-31
Identities = 101/346 (29%), Positives = 143/346 (41%), Gaps = 52/346 (15%)
Query: 96 GEHIWFETNVSGDFCYVGEQYCVARMLQKSVSRRK--CAACKIVVHTPCIEQLEKINFRC 153
G H W+ + + + + V R ++SR C CK+ H C + K C
Sbjct: 326 GMHCWYSS-----YSHRTQHCNVCRESIPALSRDAIICEVCKVKSHRLCALRASK---DC 377
Query: 154 KPSFRESGSRNVREPTFVR--HHWVHRRR----QDGKCRHCGKGFQQKFTFHSKEIVAIS 207
K + + V H WV Q C +Q+ F
Sbjct: 378 KWNTLSITDDLLLPADEVNMPHQWVEGNMPVSSQCAVCHESCGSYQRLQDFR-------- 429
Query: 208 CSWCKQAYHSKVSCFMLQQIEEPCSLGVHAAVVIPPTWILRARRPQNTLKASKKKKRASF 267
C WC H ++ + C H + VIPPT + + + +S
Sbjct: 430 CLWCNSTVHDDCR----RRFSKECCFRSHRSSVIPPTALSDPKGDGQLVVSSD------- 478
Query: 268 KRKSSKKGPEEGRWRPFIIRPTPSPLMKPLLVFVNPKSGGNQGAKIIQSFLWYLNPRQVF 327
F S PLL+F+N KSG +QG ++ F YLNP QVF
Sbjct: 479 ----------------FWNLDWSSACSCPLLIFINSKSGDHQGIVFLRKFKQYLNPSQVF 522
Query: 328 DLSQGGPKEALEMYRKVHNLRILACGGDGTVGWILSTLDQLRLKPPPPVAILPLGTGNDL 387
DL +GGP+ L M++ RIL CGGDG+V W+LS +D L +A++PLGTGNDL
Sbjct: 523 DLLKGGPEAGLSMFKNFARFRILVCGGDGSVSWVLSLIDAFGLHEKCQLAVIPLGTGNDL 582
Query: 388 ARTLNWGGGYT-DEPVSKILSHVEEGNVVQLDRWDLHAEPNPEAGP 432
AR L WG + + IL+ VE+ +V LDRW + P P
Sbjct: 583 ARVLGWGAFWNKSKSPLDILNRVEQASVRILDRWSVMIRETPRQTP 628
Score = 110 bits (275), Expect = 6e-24
Identities = 73/223 (32%), Positives = 114/223 (51%), Gaps = 16/223 (7%)
Query: 447 VFNNYFSLGFDAHVTLEFHESREANPEKFNSRFRNKMFYAGTAFSDFLMGSSKDLAKHIR 506
V NNYF +G DA ++L+F+ R+ +P ++NSR +NKM+Y + L S + L + +
Sbjct: 857 VMNNYFGIGLDAKISLDFNTRRDEHPGQYNSRLKNKMWYGLLGTKELLQRSYRKLEERVH 916
Query: 507 VVCDGMDLT-PKIQDLKPQCVVFLNIPRYCAGTMPWGHPGEHHDFEPQRHDDGYLEVIGF 565
+ CDG ++ P +Q +V LNI Y G WG ++E DDG LEV+
Sbjct: 917 LECDGETISLPNLQG-----IVVLNITSYAGGINFWGSNTATTEYEAPAIDDGKLEVVAI 971
Query: 566 TMTSLAALQ--VGGHGERLTQCREVVLTT--SKAIPVQVDGEPCKLAASRIRIALRNQAT 621
+ A+ + H R+ QC EV++T + IPVQVDGE I+I +N A
Sbjct: 972 FGSVQMAMSRIINLHHHRIAQCHEVMITIDGEEGIPVQVDGEAWIQRPGLIKIRYKNAAQ 1031
Query: 622 MVQKAK-----RRSAAPLHSDQQPVPE-QLRIQVSRVSMHDYE 658
M+ + + + H++ Q P+ QL Q S+ S+ D E
Sbjct: 1032 MLTRDRDFENSMKMWEYKHTEIQAAPQPQLDFQDSQESLSDEE 1074
>gi|223634006 hypothetical protein LOC441869 [Homo sapiens]
Length = 399
Score = 57.4 bits (137), Expect = 6e-08
Identities = 41/117 (35%), Positives = 54/117 (46%), Gaps = 2/117 (1%)
Query: 795 LIEAAKRNDFCKLQELHRAGGDLMHRDEQSRTLLHHAVSTGSKDVVRYLLDHAPPEILDA 854
L++A R + +L R G + RD RT LH AV G +VR LL P + A
Sbjct: 45 LLQAVWRGPAGLVTQLLRQGASVEERDHAGRTPLHLAVLRGHAPLVRLLLQRGAP--VGA 102
Query: 855 VEENGETCLHQAAALGQRTICHYIVEAGASLMKTDQQGDTPRQRAEKAQDTELAAYL 911
V+ G T LH+AA G + +++ GAS G TP A T LAA L
Sbjct: 103 VDRAGRTALHEAAWHGHSRVAELLLQRGASAAARSGTGLTPLHWAAALGHTLLAARL 159
Score = 43.5 bits (101), Expect = 0.001
Identities = 38/121 (31%), Positives = 51/121 (42%), Gaps = 4/121 (3%)
Query: 795 LIEAAKRNDFCKLQELHRAGGDLMHRDEQSRTLLHHAVSTGSKDVVRYLLDH-APPEILD 853
L+ AA L+ L G + RD T L A + G + LL H A P I D
Sbjct: 207 LLVAAAAGRGAALRFLLARGARVDARDGAGATALGLAAALGRSQDIEVLLGHGADPGIRD 266
Query: 854 AVEENGETCLHQAAALGQRTICHYIVEAGASLMKTDQQGDTPRQRAEKAQDTELAAYLEN 913
+G + LH+AAA G +V GA + D G TP A + E+A L +
Sbjct: 267 ---RHGRSALHRAAARGHLLAVQLLVTQGAEVDARDTLGLTPLHHASREGHVEVAGCLLD 323
Query: 914 R 914
R
Sbjct: 324 R 324
Score = 32.3 bits (72), Expect = 2.1
Identities = 24/82 (29%), Positives = 36/82 (43%), Gaps = 2/82 (2%)
Query: 814 GGDLMHRDEQSRTLLHHAVSTGSKDVVRYLLDHAPPEILDAVEENGETCLHQAAALGQRT 873
G D RD R+ LH A + G V+ L+ +DA + G T LH A+ G
Sbjct: 259 GADPGIRDRHGRSALHRAAARGHLLAVQLLVTQGAE--VDARDTLGLTPLHHASREGHVE 316
Query: 874 ICHYIVEAGASLMKTDQQGDTP 895
+ +++ GA + T TP
Sbjct: 317 VAGCLLDRGAQVDATGWLRKTP 338
>gi|20270347 ankyrin repeat domain 54 [Homo sapiens]
Length = 300
Score = 53.5 bits (127), Expect = 9e-07
Identities = 36/109 (33%), Positives = 53/109 (48%), Gaps = 4/109 (3%)
Query: 793 EELIEAAKRNDFCKLQELHRAGGDLMHRDEQSRTLLHHAVSTGSKDVVRYLLDH-APPEI 851
+ L ++A ND +Q+L G D D++ RT LH A G+ +V+ LLDH A P
Sbjct: 112 KRLRDSANANDVETVQQLLEDGADPCAADDKGRTALHFASCNGNDQIVQLLLDHGADPNQ 171
Query: 852 LDAVEENGETCLHQAAALGQRTICHYIVEAGASLMKTDQQGDTPRQRAE 900
D + G T LH AA + ++ GA + D+ G TP A+
Sbjct: 172 RDGL---GNTPLHLAACTNHVPVITTLLRGGARVDALDRAGRTPLHLAK 217
>gi|225543463 tetratricopeptide repeat, ankyrin repeat and coiled-coil
containing 1 isoform 2 [Homo sapiens]
Length = 1390
Score = 53.1 bits (126), Expect = 1e-06
Identities = 36/114 (31%), Positives = 55/114 (48%), Gaps = 2/114 (1%)
Query: 798 AAKRNDFCKLQELHRAGGDLMHRDEQSRTLLHHAVSTGSKDVVRYLLDHAPPEILDAVEE 857
AA++ + ++ L G D+ D+Q RT L A G V +LL L ++++
Sbjct: 1111 AARQGHWQIVRLLLERGCDVNLSDKQGRTPLMVAACEGHLSTVEFLLSKGAA--LSSLDK 1168
Query: 858 NGETCLHQAAALGQRTICHYIVEAGASLMKTDQQGDTPRQRAEKAQDTELAAYL 911
G + L A G R + Y+VE GA++ +TD+ G TP A D E YL
Sbjct: 1169 EGLSALSWACLKGHRAVVQYLVEEGAAIDQTDKNGRTPLDLAAFYGDAETVLYL 1222
Score = 46.6 bits (109), Expect = 1e-04
Identities = 34/117 (29%), Positives = 52/117 (44%), Gaps = 2/117 (1%)
Query: 795 LIEAAKRNDFCKLQELHRAGGDLMHRDEQSRTLLHHAVSTGSKDVVRYLLDHAPPEILDA 854
L+ AA ++ L G L D++ + L A G + VV+YL++ +D
Sbjct: 1141 LMVAACEGHLSTVEFLLSKGAALSSLDKEGLSALSWACLKGHRAVVQYLVEEGAA--IDQ 1198
Query: 855 VEENGETCLHQAAALGQRTICHYIVEAGASLMKTDQQGDTPRQRAEKAQDTELAAYL 911
++NG T L AA G Y+VE GA + D G P RA ++T + L
Sbjct: 1199 TDKNGRTPLDLAAFYGDAETVLYLVEKGAVIEHVDHSGMRPLDRAIGCRNTSVVVAL 1255
Score = 32.0 bits (71), Expect = 2.7
Identities = 31/129 (24%), Positives = 51/129 (39%), Gaps = 43/129 (33%)
Query: 810 LHRAGGDLMHRDEQSRTLLHHAVSTGSKDVVRYLL----------------DHAPPEILD 853
L + G + H D++ + L H+ G D+++YLL HA + L
Sbjct: 979 LTKKGVRVDHLDKKGQCALVHSALRGHGDILQYLLTCEWSPGPPQPGTLRKSHALQQALT 1038
Query: 854 A---------------------VEENG------ETCLHQAAALGQRTICHYIVEAGASLM 886
A VE NG ET L AA G+ +C ++ GA++
Sbjct: 1039 AAASMGHSSVVQCLLGMEKEHEVEVNGTDTLWGETALTAAAGRGKLEVCELLLGHGAAVS 1098
Query: 887 KTDQQGDTP 895
+T+++G P
Sbjct: 1099 RTNRRGVPP 1107
Score = 30.4 bits (67), Expect = 8.0
Identities = 19/58 (32%), Positives = 28/58 (48%), Gaps = 2/58 (3%)
Query: 835 GSKDVVRYLLDHAPPEILDAVEENGETCLHQAAALGQRTICHYIVEAGASLMKTDQQG 892
G ++VV LL+ LD ENG T L AAA G + + + G + D++G
Sbjct: 938 GHEEVVTLLLEFGA--CLDGTSENGMTALCYAAAAGHMKLVCLLTKKGVRVDHLDKKG 993
>gi|225543461 tetratricopeptide repeat, ankyrin repeat and coiled-coil
containing 1 isoform 1 [Homo sapiens]
Length = 1861
Score = 53.1 bits (126), Expect = 1e-06
Identities = 36/114 (31%), Positives = 55/114 (48%), Gaps = 2/114 (1%)
Query: 798 AAKRNDFCKLQELHRAGGDLMHRDEQSRTLLHHAVSTGSKDVVRYLLDHAPPEILDAVEE 857
AA++ + ++ L G D+ D+Q RT L A G V +LL L ++++
Sbjct: 1119 AARQGHWQIVRLLLERGCDVNLSDKQGRTPLMVAACEGHLSTVEFLLSKGAA--LSSLDK 1176
Query: 858 NGETCLHQAAALGQRTICHYIVEAGASLMKTDQQGDTPRQRAEKAQDTELAAYL 911
G + L A G R + Y+VE GA++ +TD+ G TP A D E YL
Sbjct: 1177 EGLSALSWACLKGHRAVVQYLVEEGAAIDQTDKNGRTPLDLAAFYGDAETVLYL 1230
Score = 46.6 bits (109), Expect = 1e-04
Identities = 34/117 (29%), Positives = 52/117 (44%), Gaps = 2/117 (1%)
Query: 795 LIEAAKRNDFCKLQELHRAGGDLMHRDEQSRTLLHHAVSTGSKDVVRYLLDHAPPEILDA 854
L+ AA ++ L G L D++ + L A G + VV+YL++ +D
Sbjct: 1149 LMVAACEGHLSTVEFLLSKGAALSSLDKEGLSALSWACLKGHRAVVQYLVEEGAA--IDQ 1206
Query: 855 VEENGETCLHQAAALGQRTICHYIVEAGASLMKTDQQGDTPRQRAEKAQDTELAAYL 911
++NG T L AA G Y+VE GA + D G P RA ++T + L
Sbjct: 1207 TDKNGRTPLDLAAFYGDAETVLYLVEKGAVIEHVDHSGMRPLDRAIGCRNTSVVVAL 1263
Score = 32.0 bits (71), Expect = 2.7
Identities = 31/129 (24%), Positives = 51/129 (39%), Gaps = 43/129 (33%)
Query: 810 LHRAGGDLMHRDEQSRTLLHHAVSTGSKDVVRYLL----------------DHAPPEILD 853
L + G + H D++ + L H+ G D+++YLL HA + L
Sbjct: 987 LTKKGVRVDHLDKKGQCALVHSALRGHGDILQYLLTCEWSPGPPQPGTLRKSHALQQALT 1046
Query: 854 A---------------------VEENG------ETCLHQAAALGQRTICHYIVEAGASLM 886
A VE NG ET L AA G+ +C ++ GA++
Sbjct: 1047 AAASMGHSSVVQCLLGMEKEHEVEVNGTDTLWGETALTAAAGRGKLEVCELLLGHGAAVS 1106
Query: 887 KTDQQGDTP 895
+T+++G P
Sbjct: 1107 RTNRRGVPP 1115
Score = 30.4 bits (67), Expect = 8.0
Identities = 19/58 (32%), Positives = 28/58 (48%), Gaps = 2/58 (3%)
Query: 835 GSKDVVRYLLDHAPPEILDAVEENGETCLHQAAALGQRTICHYIVEAGASLMKTDQQG 892
G ++VV LL+ LD ENG T L AAA G + + + G + D++G
Sbjct: 946 GHEEVVTLLLEFGA--CLDGTSENGMTALCYAAAAGHMKLVCLLTKKGVRVDHLDKKG 1001
>gi|219842212 protein phosphatase 1, regulatory (inhibitor) subunit
12A isoform a [Homo sapiens]
Length = 1030
Score = 50.8 bits (120), Expect = 6e-06
Identities = 33/124 (26%), Positives = 58/124 (46%), Gaps = 2/124 (1%)
Query: 792 GEELIEAAKRNDFCKLQELHRAGGDLMHRDEQSRTLLHHAVSTGSKDVVRYLLDHAPPEI 851
G + A D ++ +L G D+ + + T LH A + D+V++L+++
Sbjct: 41 GAVFLAACSSGDTDEVLKLLHRGADINYANVDGLTALHQACIDDNVDMVKFLVENGAN-- 98
Query: 852 LDAVEENGETCLHQAAALGQRTICHYIVEAGASLMKTDQQGDTPRQRAEKAQDTELAAYL 911
++ + G LH AA+ G I +++ GA + + +GDTP AE+ EL
Sbjct: 99 INQPDNEGWIPLHAAASCGYLDIAEFLIGQGAHVGAVNSEGDTPLDIAEEEAMEELLQNE 158
Query: 912 ENRQ 915
NRQ
Sbjct: 159 VNRQ 162
Score = 33.5 bits (75), Expect = 0.94
Identities = 33/140 (23%), Positives = 62/140 (44%), Gaps = 12/140 (8%)
Query: 791 QGEELIEAAKRNDFCKLQELHR---AG--GDLMHRDEQSRTLLHHAVSTGSKDVVRYLLD 845
QG ++ A K + L++ + +G D+ H + T LH A + G +V++ L+
Sbjct: 162 QGVDIEAARKEEERIMLRDARQWLNSGHINDVRHA-KSGGTALHVAAAKGYTEVLKLLIQ 220
Query: 846 HAPPEILDAVEENGETCLHQAAALGQRTICHYIVEAGASLMKTDQQGDTPRQRAEKAQDT 905
++ + +G T LH AA G+ C +V+ + ++ G T A D
Sbjct: 221 AGYD--VNIKDYDGWTPLHAAAHWGKEEACRILVDNLCDMEMVNKVGQT----AFDVADE 274
Query: 906 ELAAYLENRQHYQMIQREDQ 925
++ YLE Q Q + ++
Sbjct: 275 DILGYLEELQKKQNLLHSEK 294
Score = 32.0 bits (71), Expect = 2.7
Identities = 31/111 (27%), Positives = 50/111 (45%), Gaps = 23/111 (20%)
Query: 793 EELIEAAKRNDFCKLQELHRAGGDL-MHRDEQSRTLLHHA---VSTGSKDVVRYLLDHAP 848
EE +E +N E++R G D+ R E+ R +L A +++G + VR+
Sbjct: 148 EEAMEELLQN------EVNRQGVDIEAARKEEERIMLRDARQWLNSGHINDVRHA----- 196
Query: 849 PEILDAVEENGETCLHQAAALGQRTICHYIVEAGASLMKTDQQGDTPRQRA 899
++G T LH AAA G + +++AG + D G TP A
Sbjct: 197 --------KSGGTALHVAAAKGYTEVLKLLIQAGYDVNIKDYDGWTPLHAA 239
>gi|4505317 protein phosphatase 1, regulatory (inhibitor) subunit
12A isoform a [Homo sapiens]
Length = 1030
Score = 50.8 bits (120), Expect = 6e-06
Identities = 33/124 (26%), Positives = 58/124 (46%), Gaps = 2/124 (1%)
Query: 792 GEELIEAAKRNDFCKLQELHRAGGDLMHRDEQSRTLLHHAVSTGSKDVVRYLLDHAPPEI 851
G + A D ++ +L G D+ + + T LH A + D+V++L+++
Sbjct: 41 GAVFLAACSSGDTDEVLKLLHRGADINYANVDGLTALHQACIDDNVDMVKFLVENGAN-- 98
Query: 852 LDAVEENGETCLHQAAALGQRTICHYIVEAGASLMKTDQQGDTPRQRAEKAQDTELAAYL 911
++ + G LH AA+ G I +++ GA + + +GDTP AE+ EL
Sbjct: 99 INQPDNEGWIPLHAAASCGYLDIAEFLIGQGAHVGAVNSEGDTPLDIAEEEAMEELLQNE 158
Query: 912 ENRQ 915
NRQ
Sbjct: 159 VNRQ 162
Score = 33.5 bits (75), Expect = 0.94
Identities = 33/140 (23%), Positives = 62/140 (44%), Gaps = 12/140 (8%)
Query: 791 QGEELIEAAKRNDFCKLQELHR---AG--GDLMHRDEQSRTLLHHAVSTGSKDVVRYLLD 845
QG ++ A K + L++ + +G D+ H + T LH A + G +V++ L+
Sbjct: 162 QGVDIEAARKEEERIMLRDARQWLNSGHINDVRHA-KSGGTALHVAAAKGYTEVLKLLIQ 220
Query: 846 HAPPEILDAVEENGETCLHQAAALGQRTICHYIVEAGASLMKTDQQGDTPRQRAEKAQDT 905
++ + +G T LH AA G+ C +V+ + ++ G T A D
Sbjct: 221 AGYD--VNIKDYDGWTPLHAAAHWGKEEACRILVDNLCDMEMVNKVGQT----AFDVADE 274
Query: 906 ELAAYLENRQHYQMIQREDQ 925
++ YLE Q Q + ++
Sbjct: 275 DILGYLEELQKKQNLLHSEK 294
Score = 32.0 bits (71), Expect = 2.7
Identities = 31/111 (27%), Positives = 50/111 (45%), Gaps = 23/111 (20%)
Query: 793 EELIEAAKRNDFCKLQELHRAGGDL-MHRDEQSRTLLHHA---VSTGSKDVVRYLLDHAP 848
EE +E +N E++R G D+ R E+ R +L A +++G + VR+
Sbjct: 148 EEAMEELLQN------EVNRQGVDIEAARKEEERIMLRDARQWLNSGHINDVRHA----- 196
Query: 849 PEILDAVEENGETCLHQAAALGQRTICHYIVEAGASLMKTDQQGDTPRQRA 899
++G T LH AAA G + +++AG + D G TP A
Sbjct: 197 --------KSGGTALHVAAAKGYTEVLKLLIQAGYDVNIKDYDGWTPLHAA 239
>gi|134948605 ankyrin repeat domain 12 isoform 2 [Homo sapiens]
Length = 2039
Score = 50.4 bits (119), Expect = 7e-06
Identities = 43/155 (27%), Positives = 72/155 (46%), Gaps = 11/155 (7%)
Query: 755 LLGASARPDLP--TPTSPLPTSPC---SPTPRSLQGDAAPPQGEE----LIEAAKRNDFC 805
L+ +AR + P TP P T+P +P+ S Q D + E L AA R D
Sbjct: 117 LMQMTARDNSPDSTPNHPSQTTPAQKKTPSSSSRQKDKVNKRNERGETPLHMAAIRGDVK 176
Query: 806 KLQELHRAGGDLMHRDEQSRTLLHHAVSTGSKDVVRYLLDHAPPEILDAVEENGETCLHQ 865
+++EL G ++ +D T LH A + G DV + L+ +++ +T LH
Sbjct: 177 QVKELISLGANVNVKDFAGWTPLHEACNVGYYDVAKILIAAGADVNTQGLDD--DTPLHD 234
Query: 866 AAALGQRTICHYIVEAGASLMKTDQQGDTPRQRAE 900
+A+ G R I ++ G + + ++ G+ P AE
Sbjct: 235 SASSGHRDIVKLLLRHGGNPFQANKHGERPVDVAE 269
>gi|134948558 ankyrin repeat domain 12 isoform 1 [Homo sapiens]
Length = 2062
Score = 50.4 bits (119), Expect = 7e-06
Identities = 43/155 (27%), Positives = 72/155 (46%), Gaps = 11/155 (7%)
Query: 755 LLGASARPDLP--TPTSPLPTSPC---SPTPRSLQGDAAPPQGEE----LIEAAKRNDFC 805
L+ +AR + P TP P T+P +P+ S Q D + E L AA R D
Sbjct: 140 LMQMTARDNSPDSTPNHPSQTTPAQKKTPSSSSRQKDKVNKRNERGETPLHMAAIRGDVK 199
Query: 806 KLQELHRAGGDLMHRDEQSRTLLHHAVSTGSKDVVRYLLDHAPPEILDAVEENGETCLHQ 865
+++EL G ++ +D T LH A + G DV + L+ +++ +T LH
Sbjct: 200 QVKELISLGANVNVKDFAGWTPLHEACNVGYYDVAKILIAAGADVNTQGLDD--DTPLHD 257
Query: 866 AAALGQRTICHYIVEAGASLMKTDQQGDTPRQRAE 900
+A+ G R I ++ G + + ++ G+ P AE
Sbjct: 258 SASSGHRDIVKLLLRHGGNPFQANKHGERPVDVAE 292
>gi|87239981 tankyrase, TRF1-interacting ankyrin-related ADP-ribose
polymerase [Homo sapiens]
Length = 1327
Score = 50.4 bits (119), Expect = 7e-06
Identities = 41/131 (31%), Positives = 65/131 (49%), Gaps = 11/131 (8%)
Query: 783 LQGDAAPPQGEELIEAAKRNDFCKLQELHRAGGDLMHRDEQSR--TLLHHAVSTGSKDVV 840
L+GDAA L++AAK+ ++Q+L ++ RD Q R T LH A + +V
Sbjct: 801 LRGDAA------LLDAAKKGCLARVQKLCTPE-NINCRDTQGRNSTPLHLAAGYNNLEVA 853
Query: 841 RYLLDHAPPEILDAVEENGETCLHQAAALGQRTICHYIVEAGASLMKTDQQGDTPRQRAE 900
YLL+H ++A ++ G LH AA+ G I +++ + TD+ TP A
Sbjct: 854 EYLLEHGAD--VNAQDKGGLIPLHNAASYGHVDIAALLIKYNTCVNATDKWAFTPLHEAA 911
Query: 901 KAQDTELAAYL 911
+ T+L A L
Sbjct: 912 QKGRTQLCALL 922
Score = 48.1 bits (113), Expect = 4e-05
Identities = 50/177 (28%), Positives = 80/177 (45%), Gaps = 12/177 (6%)
Query: 731 DRAQEHLNYVTEIAQDEIYILDPELLGASARPDLPTPTSPLPTSPCSPTPRSLQGDAAPP 790
+ Q+ L+ T I ++ D LL AS DL T + + R L+G + P
Sbjct: 633 EAVQQILSESTPIRTSDV---DYRLLEASKAGDLETVKQLCSSQ--NVNCRDLEGRHSTP 687
Query: 791 QGEELIEAAKRNDFCKLQELHRAGGDLMHRDEQSRTLLHHAVSTGSKDVVRYLLDHAPPE 850
L AA N ++ L G D+ +D+ LH+A S G +V L+ H
Sbjct: 688 ----LHFAAGYNRVSVVEYLLHHGADVHAKDKGGLVPLHNACSYGHYEVAELLVRHGAS- 742
Query: 851 ILDAVEENGETCLHQAAALGQRTICHYIVEAGASLMKTDQQGDTPRQRAEKAQDTEL 907
++ + T LH+AAA G+ IC +++ GA K ++ G+TP K DT++
Sbjct: 743 -VNVADLWKFTPLHEAAAKGKYEICKLLLKHGADPTKKNRDGNTPLDLV-KEGDTDI 797
Score = 42.4 bits (98), Expect = 0.002
Identities = 33/115 (28%), Positives = 54/115 (46%), Gaps = 6/115 (5%)
Query: 781 RSLQGDAAPPQGEELIEAAKRNDFCKLQELHRAGGDLMHRDEQSRTLLHHAVSTGSKDVV 840
R QG + P L AA N+ + L G D+ +D+ LH+A S G D+
Sbjct: 831 RDTQGRNSTP----LHLAAGYNNLEVAEYLLEHGADVNAQDKGGLIPLHNAASYGHVDIA 886
Query: 841 RYLLDHAPPEILDAVEENGETCLHQAAALGQRTICHYIVEAGASLMKTDQQGDTP 895
L+ + ++A ++ T LH+AA G+ +C ++ GA +Q+G TP
Sbjct: 887 ALLIKYNT--CVNATDKWAFTPLHEAAQKGRTQLCALLLAHGADPTMKNQEGQTP 939
Score = 40.8 bits (94), Expect = 0.006
Identities = 26/93 (27%), Positives = 42/93 (45%), Gaps = 2/93 (2%)
Query: 810 LHRAGGDLMHRDEQSRTLLHHAVSTGSKDVVRYLLDHAPPEILDAVEENGETCLHQAAAL 869
L R G ++ +++ T LH A DV+ L H ++A++ G+T LH+AA
Sbjct: 544 LLRKGANVNEKNKDFMTPLHVAAERAHNDVMEVLHKHGAK--MNALDTLGQTALHRAALA 601
Query: 870 GQRTICHYIVEAGASLMKTDQQGDTPRQRAEKA 902
G C ++ G+ QG T Q +A
Sbjct: 602 GHLQTCRLLLSYGSDPSIISLQGFTAAQMGNEA 634
Score = 40.0 bits (92), Expect = 0.010
Identities = 35/119 (29%), Positives = 52/119 (43%), Gaps = 5/119 (4%)
Query: 795 LIEAAKRNDFCKLQELHRAGGDLMHRDEQSR--TLLHHAVSTGSKDVVRYLLDHAPPEIL 852
L+EA+K D +++L + ++ RD + R T LH A VV YLL H +
Sbjct: 654 LLEASKAGDLETVKQLC-SSQNVNCRDLEGRHSTPLHFAAGYNRVSVVEYLLHHGAD--V 710
Query: 853 DAVEENGETCLHQAAALGQRTICHYIVEAGASLMKTDQQGDTPRQRAEKAQDTELAAYL 911
A ++ G LH A + G + +V GAS+ D TP A E+ L
Sbjct: 711 HAKDKGGLVPLHNACSYGHYEVAELLVRHGASVNVADLWKFTPLHEAAAKGKYEICKLL 769
Score = 38.5 bits (88), Expect = 0.029
Identities = 41/159 (25%), Positives = 63/159 (39%), Gaps = 28/159 (17%)
Query: 766 TPTSPLPTSPCSP------TPRSLQGDAAPPQG-----------------EELIEAAKRN 802
+PTS +SP SP +P + + P G EL+EA +
Sbjct: 134 SPTSSSSSSPSSPGSSLAESPEAAGVSSTAPLGPGAAGPGTGVPAVSGALRELLEACRNG 193
Query: 803 DFCKLQELHRAGGDLMHRDEQSR--TLLHHAVSTGSKDVVRYLLDHAPPEILDAVEENGE 860
D +++ L A ++ +D R + LH A G KDVV +LL + A ++ G
Sbjct: 194 DVSRVKRLVDAA-NVNAKDMAGRKSSPLHFAAGFGRKDVVEHLLQMGAN--VHARDDGGL 250
Query: 861 TCLHQAAALGQRTICHYIVEAGASLMKTDQQGDTPRQRA 899
LH A + G + ++ GA D TP A
Sbjct: 251 IPLHNACSFGHAEVVSLLLCQGADPNARDNWNYTPLHEA 289
Score = 35.0 bits (79), Expect = 0.32
Identities = 26/86 (30%), Positives = 43/86 (50%), Gaps = 2/86 (2%)
Query: 798 AAKRNDFCKLQELHRAGGDLMHRDEQSRTLLHHAVSTGSKDVVRYLLDHAPPEILDAVEE 857
AA N +Q L + G D+ +D+ LH+A S G +V LL H ++A++
Sbjct: 376 AAGYNRVRIVQLLLQHGADVHAKDKGGLVPLHNACSYGHYEVTELLLKHG--ACVNAMDL 433
Query: 858 NGETCLHQAAALGQRTICHYIVEAGA 883
T LH+AA+ + +C ++ GA
Sbjct: 434 WQFTPLHEAASKNRVEVCSLLLSHGA 459
Score = 33.9 bits (76), Expect = 0.72
Identities = 25/78 (32%), Positives = 41/78 (52%), Gaps = 4/78 (5%)
Query: 807 LQELHRAGGDLMHRDEQSRTLLHHAVSTGSKDVVRYLL-DHAPPEILDAVEENGETCLHQ 865
++ L + G ++ RD+ LH+A S G +VV LL A P +A + T LH+
Sbjct: 232 VEHLLQMGANVHARDDGGLIPLHNACSFGHAEVVSLLLCQGADP---NARDNWNYTPLHE 288
Query: 866 AAALGQRTICHYIVEAGA 883
AA G+ +C +++ GA
Sbjct: 289 AAIKGKIDVCIVLLQHGA 306
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.318 0.134 0.413
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 41,848,355
Number of Sequences: 37866
Number of extensions: 2203777
Number of successful extensions: 19566
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 362
Number of HSP's successfully gapped in prelim test: 500
Number of HSP's that attempted gapping in prelim test: 13269
Number of HSP's gapped (non-prelim): 5885
length of query: 929
length of database: 18,247,518
effective HSP length: 112
effective length of query: 817
effective length of database: 14,006,526
effective search space: 11443331742
effective search space used: 11443331742
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.