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Search of human proteins with 41462412
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|41462412 solute carrier family 25, member 35 [Homo sapiens]
(295 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|41462412 solute carrier family 25, member 35 [Homo sapiens] 592 e-169
gi|46409330 solute carrier family 25, member 34 [Homo sapiens] 247 8e-66
gi|21361114 solute carrier family 25 (mitochondrial carrier; oxo... 117 2e-26
gi|108860679 solute carrier family 25, member 27 [Homo sapiens] 100 1e-21
gi|11225256 uncoupling protein 1 [Homo sapiens] 98 1e-20
gi|13259541 uncoupling protein 2 [Homo sapiens] 95 8e-20
gi|58197562 solute carrier family 25, member 30 [Homo sapiens] 94 1e-19
gi|13259546 uncoupling protein 3 isoform UCP3S [Homo sapiens] 93 2e-19
gi|4507807 uncoupling protein 3 isoform UCP3L [Homo sapiens] 93 2e-19
gi|4507009 solute carrier family 25, member 14 isoform UCP5L [Ho... 86 3e-17
gi|13259543 solute carrier family 25, member 14 isoform UCP5S [H... 86 3e-17
gi|20149598 solute carrier family 25 (mitochondrial carrier; dic... 70 2e-12
gi|186928856 solute carrier family 25, member 19 [Homo sapiens] 67 1e-11
gi|186928860 solute carrier family 25, member 19 [Homo sapiens] 67 1e-11
gi|186928858 solute carrier family 25, member 19 [Homo sapiens] 67 1e-11
gi|86198310 solute carrier family 25, member 29 [Homo sapiens] 67 2e-11
gi|21314739 solute carrier family 25, member 32 [Homo sapiens] 65 7e-11
gi|7657581 solute carrier family 25, member 13 isoform 2 [Homo s... 64 1e-10
gi|237649019 solute carrier family 25, member 13 isoform 1 [Homo... 64 1e-10
gi|21361103 solute carrier family 25, member 12 [Homo sapiens] 61 1e-09
gi|148491091 solute carrier family 25 member 24 isoform 1 [Homo ... 60 3e-09
gi|47458041 solute carrier family 25 member 24 isoform 2 [Homo s... 60 3e-09
gi|27544933 solute carrier family 25, member 16 [Homo sapiens] 56 3e-08
gi|60460887 solute carrier family 25, member 42 [Homo sapiens] 55 1e-07
gi|239755176 PREDICTED: similar to solute carrier family 25, mem... 55 1e-07
gi|239755174 PREDICTED: similar to solute carrier family 25, mem... 55 1e-07
gi|56699407 solute carrier family 25, member 25 isoform c [Homo ... 55 1e-07
gi|56699401 solute carrier family 25, member 25 isoform a [Homo ... 55 1e-07
gi|56699405 solute carrier family 25, member 25 isoform d [Homo ... 55 1e-07
gi|56699403 solute carrier family 25, member 25 isoform b [Homo ... 55 1e-07
>gi|41462412 solute carrier family 25, member 35 [Homo sapiens]
Length = 295
Score = 592 bits (1527), Expect = e-169
Identities = 295/295 (100%), Positives = 295/295 (100%)
Query: 1 MDFLMSGLAACGACVFTNPLEVVKTRMQLQGELQAPGTYQRHYRNVFHAFITIGKVDGLA 60
MDFLMSGLAACGACVFTNPLEVVKTRMQLQGELQAPGTYQRHYRNVFHAFITIGKVDGLA
Sbjct: 1 MDFLMSGLAACGACVFTNPLEVVKTRMQLQGELQAPGTYQRHYRNVFHAFITIGKVDGLA 60
Query: 61 ALQKGLAPALLYQFLMNGIRLGTYGLAEAGGYLHTAEGTHSPARSAAAGAMAGVMGAYLG 120
ALQKGLAPALLYQFLMNGIRLGTYGLAEAGGYLHTAEGTHSPARSAAAGAMAGVMGAYLG
Sbjct: 61 ALQKGLAPALLYQFLMNGIRLGTYGLAEAGGYLHTAEGTHSPARSAAAGAMAGVMGAYLG 120
Query: 121 SPIYMVKTHLQAQAASEIAVGHQYKHQGMFQALTEIGQKHGLVGLWRGALGGLPRVIVGS 180
SPIYMVKTHLQAQAASEIAVGHQYKHQGMFQALTEIGQKHGLVGLWRGALGGLPRVIVGS
Sbjct: 121 SPIYMVKTHLQAQAASEIAVGHQYKHQGMFQALTEIGQKHGLVGLWRGALGGLPRVIVGS 180
Query: 181 STQLCTFSSTKDLLSQWEIFPPQSWKLALVAAMMSGIAVVLAMAPFDVACTRLYNQPTDA 240
STQLCTFSSTKDLLSQWEIFPPQSWKLALVAAMMSGIAVVLAMAPFDVACTRLYNQPTDA
Sbjct: 181 STQLCTFSSTKDLLSQWEIFPPQSWKLALVAAMMSGIAVVLAMAPFDVACTRLYNQPTDA 240
Query: 241 QGKNRVPKFSATSCSASAPLLGTKDVRIVKGQTGHQLFKVTQAPGCSPILLGTQS 295
QGKNRVPKFSATSCSASAPLLGTKDVRIVKGQTGHQLFKVTQAPGCSPILLGTQS
Sbjct: 241 QGKNRVPKFSATSCSASAPLLGTKDVRIVKGQTGHQLFKVTQAPGCSPILLGTQS 295
>gi|46409330 solute carrier family 25, member 34 [Homo sapiens]
Length = 304
Score = 247 bits (631), Expect = 8e-66
Identities = 125/246 (50%), Positives = 161/246 (65%), Gaps = 6/246 (2%)
Query: 1 MDFLMSGLAACGACVFTNPLEVVKTRMQLQGELQAPGTYQRHYRNVFHAFITIGKVDGLA 60
+D ++ A C ACVFTNPLEVVKTR+QLQGELQA GTY R Y + + + DGL
Sbjct: 8 VDLVLGASACCLACVFTNPLEVVKTRLQLQGELQARGTYPRPYHGFIASVAAVARADGLW 67
Query: 61 ALQKGLAPALLYQFLMNGIRLGTYGLAEAGGYLHTAEGTHSPARSAAAGAMAGVMGAYLG 120
LQKGLA LLYQ LMNG+R Y LA G T P + AGA+AG +GA++G
Sbjct: 68 GLQKGLAAGLLYQGLMNGVRFYCYSLACQAGL------TQQPGGTVVAGAVAGALGAFVG 121
Query: 121 SPIYMVKTHLQAQAASEIAVGHQYKHQGMFQALTEIGQKHGLVGLWRGALGGLPRVIVGS 180
SP Y++KT LQAQ + +AVGHQ+ HQ + AL I ++ GL+GLW+G G +PRV+VGS
Sbjct: 122 SPAYLIKTQLQAQTVAAVAVGHQHNHQTVLGALETIWRQQGLLGLWQGVGGAVPRVMVGS 181
Query: 181 STQLCTFSSTKDLLSQWEIFPPQSWKLALVAAMMSGIAVVLAMAPFDVACTRLYNQPTDA 240
+ QL TF+S K + + + P SW +AL M+S IAVV+ M PFDV TRLYNQP D
Sbjct: 182 AAQLATFASAKAWVQKQQWLPEDSWLVALAGGMISSIAVVVVMTPFDVVSTRLYNQPVDT 241
Query: 241 QGKNRV 246
G+ ++
Sbjct: 242 AGRGQL 247
Score = 28.1 bits (61), Expect = 9.6
Identities = 20/64 (31%), Positives = 30/64 (46%), Gaps = 2/64 (3%)
Query: 8 LAACGACVFTNPLEVVKTRMQLQGELQAPGTYQRHYRNVFHAFITIGKVDGLAALQKGLA 67
+++ V P +VV TR+ Q + G Q Y + + I + +G AL KGL
Sbjct: 215 ISSIAVVVVMTPFDVVSTRLYNQ-PVDTAGRGQL-YGGLTDCMVKIWRQEGPLALYKGLG 272
Query: 68 PALL 71
PA L
Sbjct: 273 PAYL 276
>gi|21361114 solute carrier family 25 (mitochondrial carrier;
oxoglutarate carrier), member 11 [Homo sapiens]
Length = 314
Score = 117 bits (292), Expect = 2e-26
Identities = 79/234 (33%), Positives = 116/234 (49%), Gaps = 10/234 (4%)
Query: 3 FLMSGLAACGACVFTNPLEVVKTRMQLQGELQAPGTYQRHYRNVFHAFITIGKVDGLAAL 62
FL GLA GA VF PL++VK RMQL GE G R Y+ FHA +I K +GL +
Sbjct: 25 FLFGGLAGMGATVFVQPLDLVKNRMQLSGE----GAKTREYKTSFHALTSILKAEGLRGI 80
Query: 63 QKGLAPALLYQFLMNGIRLGTYGLAEAGGYLHTAEGTHSP-ARSAAAGAMAGVMGAYLGS 121
GL+ LL Q RLG Y + L A+GT A G AG GA++G+
Sbjct: 81 YTGLSAGLLRQATYTTTRLGIYTVLFE--RLTGADGTPPGFLLKAVIGMTAGATGAFVGT 138
Query: 122 PIYMVKTHLQAQAASEIAVGHQYKHQGMFQALTEIGQKHGLVGLWRGALGGLPRVIVGSS 181
P + + A + + ++ +F AL I ++ G++ LWRG + + R +V ++
Sbjct: 139 PAEVALIRMTAD--GRLPADQRRGYKNVFNALIRITREEGVLTLWRGCIPTMARAVVVNA 196
Query: 182 TQLCTFSSTKDLLSQWEIFPPQSWKLALVAAMMSGIAVVLAMAPFDVACTRLYN 235
QL ++S +K L F + A+M+SG+ A P D+A TR+ N
Sbjct: 197 AQLASYSQSKQFLLDSGYF-SDNILCHFCASMISGLVTTAASMPVDIAKTRIQN 249
>gi|108860679 solute carrier family 25, member 27 [Homo sapiens]
Length = 323
Score = 100 bits (250), Expect = 1e-21
Identities = 81/265 (30%), Positives = 132/265 (49%), Gaps = 16/265 (6%)
Query: 3 FLMSGLAACGACVFTNPLEVVKTRMQLQGE--LQAPGTYQRH---YRNVFHAFITIGKVD 57
FL+SG AA A + T PL++ KTR+Q+QGE L G R YR + + I + +
Sbjct: 23 FLLSGCAATVAELATFPLDLTKTRLQMQGEAALARLGDGARESAPYRGMVRTALGIIEEE 82
Query: 58 GLAALQKGLAPALLYQFLMNGIRLGTY-GLAEAGGYLHTAEGTHSPA-RSAAAGAMAGVM 115
G L +G+ PA+ + +G R+ TY L E +E H P +S G MAGV+
Sbjct: 83 GFLKLWQGVTPAIYRHVVYSGGRMVTYEHLREV--VFGKSEDEHYPLWKSVIGGMMAGVI 140
Query: 116 GAYLGSPIYMVKTHLQAQAASEIAVGHQYKHQGMFQALTEIGQKHGLVGLWRGALGGLPR 175
G +L +P +VK +Q + ++ G + +G+ A +I + G+ GLW G + + R
Sbjct: 141 GQFLANPTDLVKVQMQMEGKRKLE-GKPLRFRGVHHAFAKILAEGGIRGLWAGWVPNIQR 199
Query: 176 VIVGSSTQLCTFSSTKDLLSQWEIFPPQSWKLAL--VAAMMSGIAVVLAMAPFDVACTRL 233
+ + L T+ + K L + P + ++++ SG+ + P DV +R+
Sbjct: 200 AALVNMGDLTTYDTVKHYL---VLNTPLEDNIMTHGLSSLCSGLVASILGTPADVIKSRI 256
Query: 234 YNQPTDAQGKNRVPKFSATSCSASA 258
NQP D QG+ + K S+T C A
Sbjct: 257 MNQPRDKQGRGLLYK-SSTDCLIQA 280
>gi|11225256 uncoupling protein 1 [Homo sapiens]
Length = 307
Score = 97.8 bits (242), Expect = 1e-20
Identities = 70/233 (30%), Positives = 106/233 (45%), Gaps = 9/233 (3%)
Query: 6 SGLAACGACVFTNPLEVVKTRMQLQGELQAPGTYQRHYRNVFHAFITIGKVDGLAALQKG 65
+G+AAC A V T PL+ K R+Q+QGE P + Y+ V + K +G L G
Sbjct: 20 AGIAACLADVITFPLDTAKVRLQVQGE--CPTSSVIRYKGVLGTITAVVKTEGRMKLYSG 77
Query: 66 LAPALLYQFLMNGIRLGTYGLAEAGGYLHTAEGTH-SPARSAAAGAMAGVMGAYLGSPIY 124
L L Q +R+G Y + +L + T S AG G + ++G P
Sbjct: 78 LPAGLQRQISSASLRIGLYDTVQE--FLTAGKETAPSLGSKILAGLTTGGVAVFIGQPTE 135
Query: 125 MVKTHLQAQAASEIAVGHQYKHQGMFQALTEIGQKHGLVGLWRGALGGLPRVIVGSSTQL 184
+VK LQAQ+ G + ++ G + A I GL GLW+G L R ++ + T+L
Sbjct: 136 VVKVRLQAQSHLH---GIKPRYTGTYNAYRIIATTEGLTGLWKGTTPNLMRSVIINCTEL 192
Query: 185 CTFSSTKDLLSQWEIFPPQSWKLALVAAMMSGIAVVLAMAPFDVACTRLYNQP 237
T+ K+ + I LV+A+++G +P DV TR N P
Sbjct: 193 VTYDLMKEAFVKNNIL-ADDVPCHLVSALIAGFCATAMSSPVDVVKTRFINSP 244
>gi|13259541 uncoupling protein 2 [Homo sapiens]
Length = 309
Score = 94.7 bits (234), Expect = 8e-20
Identities = 68/236 (28%), Positives = 105/236 (44%), Gaps = 11/236 (4%)
Query: 3 FLMSGLAACGACVFTNPLEVVKTRMQLQGELQAP--GTYQRHYRNVFHAFITIGKVDGLA 60
FL +G AAC A + T PL+ K R+Q+QGE Q P T YR V +T+ + +G
Sbjct: 17 FLGAGTAACIADLITFPLDTAKVRLQIQGESQGPVRATASAQYRGVMGTILTMVRTEGPR 76
Query: 61 ALQKGLAPALLYQFLMNGIRLGTYGLAEAGGYLHTAEGTHSPARS-AAAGAMAGVMGAYL 119
+L GL L Q +R+G Y ++ +T H+ S AG+ G + +
Sbjct: 77 SLYNGLVAGLQRQMSFASVRIGLY---DSVKQFYTKGSEHASIGSRLLAGSTTGALAVAV 133
Query: 120 GSPIYMVKTHLQAQAASEIAVGHQYKHQGMFQALTEIGQKHGLVGLWRGALGGLPRVIVG 179
P +VK QAQA + G ++Q A I ++ G GLW+G + R +
Sbjct: 134 AQPTDVVKVRFQAQARA----GGGRRYQSTVNAYKTIAREEGFRGLWKGTSPNVARNAIV 189
Query: 180 SSTQLCTFSSTKDLLSQWEIFPPQSWKLALVAAMMSGIAVVLAMAPFDVACTRLYN 235
+ +L T+ KD L + + +A +G + +P DV TR N
Sbjct: 190 NCAELVTYDLIKDALLKANLM-TDDLPCHFTSAFGAGFCTTVIASPVDVVKTRYMN 244
>gi|58197562 solute carrier family 25, member 30 [Homo sapiens]
Length = 291
Score = 94.0 bits (232), Expect = 1e-19
Identities = 69/241 (28%), Positives = 114/241 (47%), Gaps = 11/241 (4%)
Query: 3 FLMSGLAACGACVFTNPLEVVKTRMQLQGELQAPGTYQRHYRNVFHAFITIGKVDGLAAL 62
F+ GLA+ A T P+++ KTR+Q+QG+ + YR + HA + IG+ +GL AL
Sbjct: 9 FVYGGLASITAECGTFPIDLTKTRLQIQGQTNDAKFKEIRYRGMLHALVRIGREEGLKAL 68
Query: 63 QKGLAPALLYQFLMNGIRLGTYGLAEAGGYLHTAEGTHSPARSAAAGAMAGVMGAYLGSP 122
G+APA+L Q I++GTY + ++ E P + G ++GV+ + + +P
Sbjct: 69 YSGIAPAMLRQASYGTIKIGTYQSLKR-LFIERPEDETLPI-NVICGILSGVISSTIANP 126
Query: 123 IYMVKTHLQAQAASEIAVGHQYKHQGMFQALTEIGQKHGLVGLWRGALGGLPRVIVGSST 182
++K +QAQ+ + GM I Q+ G GLW+G R +
Sbjct: 127 TDVLKIRMQAQSNT--------IQGGMIGNFMNIYQQEGTRGLWKGVSLTAQRAAIVVGV 178
Query: 183 QLCTFSSTKDLLSQWEIFPPQSWKLALVAAMMSGIAVVLAMAPFDVACTRLYNQPTDAQG 242
+L + TK L + + +++ G+A LA P DV TR+ NQ G
Sbjct: 179 ELPVYDITKKHLILSGLMGDTVY-THFLSSFTCGLAGALASNPVDVVRTRMMNQRVLRDG 237
Query: 243 K 243
+
Sbjct: 238 R 238
>gi|13259546 uncoupling protein 3 isoform UCP3S [Homo sapiens]
Length = 275
Score = 93.2 bits (230), Expect = 2e-19
Identities = 69/241 (28%), Positives = 111/241 (46%), Gaps = 14/241 (5%)
Query: 3 FLMSGLAACGACVFTNPLEVVKTRMQLQGELQAPGTYQR-HYRNVFHAFITIGKVDGLAA 61
FL +G AAC A + T PL+ K R+Q+QGE QA T + YR V +T+ + +G +
Sbjct: 17 FLGAGTAACFADLVTFPLDTAKVRLQIQGENQAVQTARLVQYRGVLGTILTMVRTEGPCS 76
Query: 62 LQKGLAPALLYQFLMNGIRLGTYGLAEAGGYLHTAEGTHSPARSA--AAGAMAGVMGAYL 119
GL L Q IR+G Y ++ ++T +G + + + AG G M
Sbjct: 77 PYNGLVAGLQRQMSFASIRIGLY---DSVKQVYTPKGADNSSLTTRILAGCTTGAMAVTC 133
Query: 120 GSPIYMVKTHLQAQAASEIAVG---HQYKHQGMFQALTEIGQKHGLVGLWRGALGGLPRV 176
P +VK QA I +G K+ G A I ++ G+ GLW+G L + R
Sbjct: 134 AQPTDVVKVRFQA----SIHLGPSRSDRKYSGTMDAYRTIAREEGVRGLWKGTLPNIMRN 189
Query: 177 IVGSSTQLCTFSSTKDLLSQWEIFPPQSWKLALVAAMMSGIAVVLAMAPFDVACTRLYNQ 236
+ + ++ T+ K+ L + + ++ V+A +G + +P DV TR N
Sbjct: 190 AIVNCAEVVTYDILKEKLLDYHLL-TDNFPCHFVSAFGAGFCATVVASPVDVVKTRYMNS 248
Query: 237 P 237
P
Sbjct: 249 P 249
>gi|4507807 uncoupling protein 3 isoform UCP3L [Homo sapiens]
Length = 312
Score = 93.2 bits (230), Expect = 2e-19
Identities = 69/241 (28%), Positives = 111/241 (46%), Gaps = 14/241 (5%)
Query: 3 FLMSGLAACGACVFTNPLEVVKTRMQLQGELQAPGTYQR-HYRNVFHAFITIGKVDGLAA 61
FL +G AAC A + T PL+ K R+Q+QGE QA T + YR V +T+ + +G +
Sbjct: 17 FLGAGTAACFADLVTFPLDTAKVRLQIQGENQAVQTARLVQYRGVLGTILTMVRTEGPCS 76
Query: 62 LQKGLAPALLYQFLMNGIRLGTYGLAEAGGYLHTAEGTHSPARSA--AAGAMAGVMGAYL 119
GL L Q IR+G Y ++ ++T +G + + + AG G M
Sbjct: 77 PYNGLVAGLQRQMSFASIRIGLY---DSVKQVYTPKGADNSSLTTRILAGCTTGAMAVTC 133
Query: 120 GSPIYMVKTHLQAQAASEIAVG---HQYKHQGMFQALTEIGQKHGLVGLWRGALGGLPRV 176
P +VK QA I +G K+ G A I ++ G+ GLW+G L + R
Sbjct: 134 AQPTDVVKVRFQA----SIHLGPSRSDRKYSGTMDAYRTIAREEGVRGLWKGTLPNIMRN 189
Query: 177 IVGSSTQLCTFSSTKDLLSQWEIFPPQSWKLALVAAMMSGIAVVLAMAPFDVACTRLYNQ 236
+ + ++ T+ K+ L + + ++ V+A +G + +P DV TR N
Sbjct: 190 AIVNCAEVVTYDILKEKLLDYHLL-TDNFPCHFVSAFGAGFCATVVASPVDVVKTRYMNS 248
Query: 237 P 237
P
Sbjct: 249 P 249
>gi|4507009 solute carrier family 25, member 14 isoform UCP5L [Homo
sapiens]
Length = 325
Score = 86.3 bits (212), Expect = 3e-17
Identities = 70/235 (29%), Positives = 113/235 (48%), Gaps = 13/235 (5%)
Query: 3 FLMSGLAACGACVFTNPLEVVKTRMQLQGELQAPGTYQRHYRNVFHAFITIGKVDGLAAL 62
F+ GLA+ A T P+++ KTR+Q+QG+ + YR +FHA I K +G+ AL
Sbjct: 44 FVYGGLASIVAEFGTFPVDLTKTRLQVQGQSIDARFKEIKYRGMFHALFRICKEEGVLAL 103
Query: 63 QKGLAPALLYQFLMNGIRLGTYGLAEAGGYLHTAEGTHSPARSAAAGAMAGVMGAYLGSP 122
G+APALL Q I++G Y + ++ E + + G ++GV+ + + +P
Sbjct: 104 YSGIAPALLRQASYGTIKIGIYQSLKR-LFVERLE-DETLLINMICGVVSGVISSTIANP 161
Query: 123 IYMVKTHLQAQAASEIAVGHQYKHQG-MFQALTEIGQKHGLVGLWRGALGGLPRVIVGSS 181
++K +QAQ + QG M + +I Q+ G GLWRG + R +
Sbjct: 162 TDVLKIRMQAQGS---------LFQGSMIGSFIDIYQQEGTRGLWRGVVPTAQRAAIVVG 212
Query: 182 TQLCTFSSTKDLLSQWEIFPPQSWKLALVAAMMSGIAVVLAMAPFDVACTRLYNQ 236
+L + TK L + + V++ G+A LA P DV TR+ NQ
Sbjct: 213 VELPVYDITKKHLILSGMM-GDTILTHFVSSFTCGLAGALASNPVDVVRTRMMNQ 266
Score = 48.5 bits (114), Expect = 7e-06
Identities = 37/151 (24%), Positives = 67/151 (44%), Gaps = 12/151 (7%)
Query: 18 NPLEVVKTRMQLQGELQAPGTYQRHYRNVFHAFITIGKVDGLAALQKGLAPALLYQFLMN 77
NP +V+K RMQ QG L ++ +FI I + +G L +G+ P ++
Sbjct: 160 NPTDVLKIRMQAQGSL--------FQGSMIGSFIDIYQQEGTRGLWRGVVPTAQRAAIVV 211
Query: 78 GIRLGTYGLAEAGGYLHTAEGTHSPARSAAAGAMAGVMGAYLGSPIYMVKTHLQAQAASE 137
G+ L Y + + L G + + G+ GA +P+ +V+T + Q A
Sbjct: 212 GVELPVYDITKKHLILSGMMGD-TILTHFVSSFTCGLAGALASNPVDVVRTRMMNQRA-- 268
Query: 138 IAVGHQYKHQGMFQALTEIGQKHGLVGLWRG 168
VGH ++G + ++ + G L++G
Sbjct: 269 -IVGHVDLYKGTVDGILKMWKHEGFFALYKG 298
>gi|13259543 solute carrier family 25, member 14 isoform UCP5S [Homo
sapiens]
Length = 322
Score = 86.3 bits (212), Expect = 3e-17
Identities = 70/235 (29%), Positives = 113/235 (48%), Gaps = 13/235 (5%)
Query: 3 FLMSGLAACGACVFTNPLEVVKTRMQLQGELQAPGTYQRHYRNVFHAFITIGKVDGLAAL 62
F+ GLA+ A T P+++ KTR+Q+QG+ + YR +FHA I K +G+ AL
Sbjct: 41 FVYGGLASIVAEFGTFPVDLTKTRLQVQGQSIDARFKEIKYRGMFHALFRICKEEGVLAL 100
Query: 63 QKGLAPALLYQFLMNGIRLGTYGLAEAGGYLHTAEGTHSPARSAAAGAMAGVMGAYLGSP 122
G+APALL Q I++G Y + ++ E + + G ++GV+ + + +P
Sbjct: 101 YSGIAPALLRQASYGTIKIGIYQSLKR-LFVERLE-DETLLINMICGVVSGVISSTIANP 158
Query: 123 IYMVKTHLQAQAASEIAVGHQYKHQG-MFQALTEIGQKHGLVGLWRGALGGLPRVIVGSS 181
++K +QAQ + QG M + +I Q+ G GLWRG + R +
Sbjct: 159 TDVLKIRMQAQGS---------LFQGSMIGSFIDIYQQEGTRGLWRGVVPTAQRAAIVVG 209
Query: 182 TQLCTFSSTKDLLSQWEIFPPQSWKLALVAAMMSGIAVVLAMAPFDVACTRLYNQ 236
+L + TK L + + V++ G+A LA P DV TR+ NQ
Sbjct: 210 VELPVYDITKKHLILSGMM-GDTILTHFVSSFTCGLAGALASNPVDVVRTRMMNQ 263
Score = 48.5 bits (114), Expect = 7e-06
Identities = 37/151 (24%), Positives = 67/151 (44%), Gaps = 12/151 (7%)
Query: 18 NPLEVVKTRMQLQGELQAPGTYQRHYRNVFHAFITIGKVDGLAALQKGLAPALLYQFLMN 77
NP +V+K RMQ QG L ++ +FI I + +G L +G+ P ++
Sbjct: 157 NPTDVLKIRMQAQGSL--------FQGSMIGSFIDIYQQEGTRGLWRGVVPTAQRAAIVV 208
Query: 78 GIRLGTYGLAEAGGYLHTAEGTHSPARSAAAGAMAGVMGAYLGSPIYMVKTHLQAQAASE 137
G+ L Y + + L G + + G+ GA +P+ +V+T + Q A
Sbjct: 209 GVELPVYDITKKHLILSGMMGD-TILTHFVSSFTCGLAGALASNPVDVVRTRMMNQRA-- 265
Query: 138 IAVGHQYKHQGMFQALTEIGQKHGLVGLWRG 168
VGH ++G + ++ + G L++G
Sbjct: 266 -IVGHVDLYKGTVDGILKMWKHEGFFALYKG 295
>gi|20149598 solute carrier family 25 (mitochondrial carrier;
dicarboxylate transporter), member 10 [Homo sapiens]
Length = 287
Score = 70.5 bits (171), Expect = 2e-12
Identities = 58/239 (24%), Positives = 101/239 (42%), Gaps = 19/239 (7%)
Query: 7 GLAACGACVFTNPLEVVKTRMQLQGELQAPGTYQRHYRNVFHAFITIGKVDGLAALQKGL 66
GLA+CGA T+PL+++K +Q Q E++ T + + + DG+ AL GL
Sbjct: 14 GLASCGAACCTHPLDLLKVHLQTQQEVKLRMTGMA---------LRVVRTDGILALYSGL 64
Query: 67 APALLYQFLMNGIRLGTYGLAEAGGYLHTAEGTHSPA---RSAAAGAMAGVMGAYLGSPI 123
+ +L Q + R Y A+G+ P G+++G+ G ++G+P
Sbjct: 65 SASLCRQMTYSLTRFAIYETVRD----RVAKGSQGPLPFHEKVLLGSVSGLAGGFVGTPA 120
Query: 124 YMVKTHLQAQAASEIAVGHQYKHQGMFQALTEIGQKHGLVGLWRGALGGLPRVIVGSSTQ 183
+V +Q ++ G + + L + ++ GL L+ GA R + + Q
Sbjct: 121 DLVNVRMQNDV--KLPQGQRRNYAHALDGLYRVAREEGLRRLFSGATMASSRGALVTVGQ 178
Query: 184 LCTFSSTKDLLSQWEIFPPQSWKLALVAAMMSGIAVVLAMAPFDVACTRLYNQPTDAQG 242
L + K L+ + VA+ ++G P DV TRL N + QG
Sbjct: 179 LSCYDQAKQLVLSTGYLSDNIF-THFVASFIAGGCATFLCQPLDVLKTRLMNSKGEYQG 236
Score = 32.7 bits (73), Expect = 0.39
Identities = 25/68 (36%), Positives = 33/68 (48%), Gaps = 12/68 (17%)
Query: 3 FLMSGLAACGACVFTNPLEVVKTR-MQLQGELQAPGTYQRHYRNVFHAFITIGKVDGLAA 61
F+ S +A A PL+V+KTR M +GE Y+ VFH + K+ G A
Sbjct: 203 FVASFIAGGCATFLCQPLDVLKTRLMNSKGE----------YQGVFHCAVETAKL-GPLA 251
Query: 62 LQKGLAPA 69
KGL PA
Sbjct: 252 FYKGLVPA 259
>gi|186928856 solute carrier family 25, member 19 [Homo sapiens]
Length = 320
Score = 67.4 bits (163), Expect = 1e-11
Identities = 49/170 (28%), Positives = 82/170 (48%), Gaps = 11/170 (6%)
Query: 3 FLMSGLAACGACVFTNPLEVVKTRMQLQGELQAPGTYQRHYRNVFHAFITIGKVDGLAAL 62
F+ GLAAC A + +P++V++TR QGE + Y + HA T+ + +G
Sbjct: 122 FVCGGLAACMATLTVHPVDVLRTRFAAQGE-------PKVYNTLRHAVGTMYRSEGPQVF 174
Query: 63 QKGLAPALLYQFLMNGIRLGTY-GLAEAGGYLHTAEG-THSPARSAAAGAMAGVMGAYLG 120
KGLAP L+ F G++ Y L + AEG + ++ G+ AGV+ L
Sbjct: 175 YKGLAPTLIAIFPYAGLQFSCYSSLKHLYKWAIPAEGKKNENLQNLLCGSGAGVISKTLT 234
Query: 121 SPIYMVKTHLQAQA--ASEIAVGHQYKHQGMFQALTEIGQKHGLVGLWRG 168
P+ + K LQ + A G +++G+ ++ QK G +G ++G
Sbjct: 235 YPLDLFKKRLQVGGFEHARAAFGQVRRYKGLMDCAKQVLQKEGALGFFKG 284
Score = 47.8 bits (112), Expect = 1e-05
Identities = 34/141 (24%), Positives = 62/141 (43%), Gaps = 5/141 (3%)
Query: 106 AAAGAMAGVMGAYLGSPIYMVKTHLQAQAASEIAVGHQYKHQGMFQALTEIGQKHGLVGL 165
A AG+++G++ L SP ++K Q Q K+ G+ QA +I Q+ G
Sbjct: 19 AVAGSVSGLVTRALISPFDVIKIRFQLQHERLSRSDPSAKYHGILQASRQILQEEGPTAF 78
Query: 166 WRGALGGLPRVIVGSSTQLCTFSSTKDLLSQWEIFPPQSWKLALVAAMMSGIAVVLAMAP 225
W+G + I + Q +F +L+ + ++ + + + V ++ L + P
Sbjct: 79 WKGHVPAQILSIGYGAVQFLSFEMLTELVHRGSVYDAREFSVHFVCGGLAACMATLTVHP 138
Query: 226 FDVACTRLYNQPTDAQGKNRV 246
DV TR AQG+ +V
Sbjct: 139 VDVLRTRF-----AAQGEPKV 154
Score = 38.1 bits (87), Expect = 0.009
Identities = 29/137 (21%), Positives = 54/137 (39%), Gaps = 6/137 (4%)
Query: 18 NPLEVVKTRMQLQGELQAPGTYQRHYRNVFHAFITIGKVDGLAALQKGLAPALLYQFLMN 77
+P +V+K R QLQ E + Y + A I + +G A KG PA +
Sbjct: 34 SPFDVIKIRFQLQHERLSRSDPSAKYHGILQASRQILQEEGPTAFWKGHVPAQILSIGYG 93
Query: 78 GIRLGTYGLAEAGGYLHTAEGTHSPARSAAAGAMAGVMGAYLGSPIYMVKTHLQAQAASE 137
++ ++ + + + + G +A M P+ +++T AQ +
Sbjct: 94 AVQFLSFEMLTELVHRGSVYDAREFSVHFVCGGLAACMATLTVHPVDVLRTRFAAQGEPK 153
Query: 138 I------AVGHQYKHQG 148
+ AVG Y+ +G
Sbjct: 154 VYNTLRHAVGTMYRSEG 170
Score = 31.6 bits (70), Expect = 0.87
Identities = 20/70 (28%), Positives = 33/70 (47%), Gaps = 2/70 (2%)
Query: 17 TNPLEVVKTRMQLQGELQAPGTYQ--RHYRNVFHAFITIGKVDGLAALQKGLAPALLYQF 74
T PL++ K R+Q+ G A + R Y+ + + + +G KGL+P+LL
Sbjct: 234 TYPLDLFKKRLQVGGFEHARAAFGQVRRYKGLMDCAKQVLQKEGALGFFKGLSPSLLKAA 293
Query: 75 LMNGIRLGTY 84
L G +Y
Sbjct: 294 LSTGFMFFSY 303
>gi|186928860 solute carrier family 25, member 19 [Homo sapiens]
Length = 320
Score = 67.4 bits (163), Expect = 1e-11
Identities = 49/170 (28%), Positives = 82/170 (48%), Gaps = 11/170 (6%)
Query: 3 FLMSGLAACGACVFTNPLEVVKTRMQLQGELQAPGTYQRHYRNVFHAFITIGKVDGLAAL 62
F+ GLAAC A + +P++V++TR QGE + Y + HA T+ + +G
Sbjct: 122 FVCGGLAACMATLTVHPVDVLRTRFAAQGE-------PKVYNTLRHAVGTMYRSEGPQVF 174
Query: 63 QKGLAPALLYQFLMNGIRLGTY-GLAEAGGYLHTAEG-THSPARSAAAGAMAGVMGAYLG 120
KGLAP L+ F G++ Y L + AEG + ++ G+ AGV+ L
Sbjct: 175 YKGLAPTLIAIFPYAGLQFSCYSSLKHLYKWAIPAEGKKNENLQNLLCGSGAGVISKTLT 234
Query: 121 SPIYMVKTHLQAQA--ASEIAVGHQYKHQGMFQALTEIGQKHGLVGLWRG 168
P+ + K LQ + A G +++G+ ++ QK G +G ++G
Sbjct: 235 YPLDLFKKRLQVGGFEHARAAFGQVRRYKGLMDCAKQVLQKEGALGFFKG 284
Score = 47.8 bits (112), Expect = 1e-05
Identities = 34/141 (24%), Positives = 62/141 (43%), Gaps = 5/141 (3%)
Query: 106 AAAGAMAGVMGAYLGSPIYMVKTHLQAQAASEIAVGHQYKHQGMFQALTEIGQKHGLVGL 165
A AG+++G++ L SP ++K Q Q K+ G+ QA +I Q+ G
Sbjct: 19 AVAGSVSGLVTRALISPFDVIKIRFQLQHERLSRSDPSAKYHGILQASRQILQEEGPTAF 78
Query: 166 WRGALGGLPRVIVGSSTQLCTFSSTKDLLSQWEIFPPQSWKLALVAAMMSGIAVVLAMAP 225
W+G + I + Q +F +L+ + ++ + + + V ++ L + P
Sbjct: 79 WKGHVPAQILSIGYGAVQFLSFEMLTELVHRGSVYDAREFSVHFVCGGLAACMATLTVHP 138
Query: 226 FDVACTRLYNQPTDAQGKNRV 246
DV TR AQG+ +V
Sbjct: 139 VDVLRTRF-----AAQGEPKV 154
Score = 38.1 bits (87), Expect = 0.009
Identities = 29/137 (21%), Positives = 54/137 (39%), Gaps = 6/137 (4%)
Query: 18 NPLEVVKTRMQLQGELQAPGTYQRHYRNVFHAFITIGKVDGLAALQKGLAPALLYQFLMN 77
+P +V+K R QLQ E + Y + A I + +G A KG PA +
Sbjct: 34 SPFDVIKIRFQLQHERLSRSDPSAKYHGILQASRQILQEEGPTAFWKGHVPAQILSIGYG 93
Query: 78 GIRLGTYGLAEAGGYLHTAEGTHSPARSAAAGAMAGVMGAYLGSPIYMVKTHLQAQAASE 137
++ ++ + + + + G +A M P+ +++T AQ +
Sbjct: 94 AVQFLSFEMLTELVHRGSVYDAREFSVHFVCGGLAACMATLTVHPVDVLRTRFAAQGEPK 153
Query: 138 I------AVGHQYKHQG 148
+ AVG Y+ +G
Sbjct: 154 VYNTLRHAVGTMYRSEG 170
Score = 31.6 bits (70), Expect = 0.87
Identities = 20/70 (28%), Positives = 33/70 (47%), Gaps = 2/70 (2%)
Query: 17 TNPLEVVKTRMQLQGELQAPGTYQ--RHYRNVFHAFITIGKVDGLAALQKGLAPALLYQF 74
T PL++ K R+Q+ G A + R Y+ + + + +G KGL+P+LL
Sbjct: 234 TYPLDLFKKRLQVGGFEHARAAFGQVRRYKGLMDCAKQVLQKEGALGFFKGLSPSLLKAA 293
Query: 75 LMNGIRLGTY 84
L G +Y
Sbjct: 294 LSTGFMFFSY 303
>gi|186928858 solute carrier family 25, member 19 [Homo sapiens]
Length = 320
Score = 67.4 bits (163), Expect = 1e-11
Identities = 49/170 (28%), Positives = 82/170 (48%), Gaps = 11/170 (6%)
Query: 3 FLMSGLAACGACVFTNPLEVVKTRMQLQGELQAPGTYQRHYRNVFHAFITIGKVDGLAAL 62
F+ GLAAC A + +P++V++TR QGE + Y + HA T+ + +G
Sbjct: 122 FVCGGLAACMATLTVHPVDVLRTRFAAQGE-------PKVYNTLRHAVGTMYRSEGPQVF 174
Query: 63 QKGLAPALLYQFLMNGIRLGTY-GLAEAGGYLHTAEG-THSPARSAAAGAMAGVMGAYLG 120
KGLAP L+ F G++ Y L + AEG + ++ G+ AGV+ L
Sbjct: 175 YKGLAPTLIAIFPYAGLQFSCYSSLKHLYKWAIPAEGKKNENLQNLLCGSGAGVISKTLT 234
Query: 121 SPIYMVKTHLQAQA--ASEIAVGHQYKHQGMFQALTEIGQKHGLVGLWRG 168
P+ + K LQ + A G +++G+ ++ QK G +G ++G
Sbjct: 235 YPLDLFKKRLQVGGFEHARAAFGQVRRYKGLMDCAKQVLQKEGALGFFKG 284
Score = 47.8 bits (112), Expect = 1e-05
Identities = 34/141 (24%), Positives = 62/141 (43%), Gaps = 5/141 (3%)
Query: 106 AAAGAMAGVMGAYLGSPIYMVKTHLQAQAASEIAVGHQYKHQGMFQALTEIGQKHGLVGL 165
A AG+++G++ L SP ++K Q Q K+ G+ QA +I Q+ G
Sbjct: 19 AVAGSVSGLVTRALISPFDVIKIRFQLQHERLSRSDPSAKYHGILQASRQILQEEGPTAF 78
Query: 166 WRGALGGLPRVIVGSSTQLCTFSSTKDLLSQWEIFPPQSWKLALVAAMMSGIAVVLAMAP 225
W+G + I + Q +F +L+ + ++ + + + V ++ L + P
Sbjct: 79 WKGHVPAQILSIGYGAVQFLSFEMLTELVHRGSVYDAREFSVHFVCGGLAACMATLTVHP 138
Query: 226 FDVACTRLYNQPTDAQGKNRV 246
DV TR AQG+ +V
Sbjct: 139 VDVLRTRF-----AAQGEPKV 154
Score = 38.1 bits (87), Expect = 0.009
Identities = 29/137 (21%), Positives = 54/137 (39%), Gaps = 6/137 (4%)
Query: 18 NPLEVVKTRMQLQGELQAPGTYQRHYRNVFHAFITIGKVDGLAALQKGLAPALLYQFLMN 77
+P +V+K R QLQ E + Y + A I + +G A KG PA +
Sbjct: 34 SPFDVIKIRFQLQHERLSRSDPSAKYHGILQASRQILQEEGPTAFWKGHVPAQILSIGYG 93
Query: 78 GIRLGTYGLAEAGGYLHTAEGTHSPARSAAAGAMAGVMGAYLGSPIYMVKTHLQAQAASE 137
++ ++ + + + + G +A M P+ +++T AQ +
Sbjct: 94 AVQFLSFEMLTELVHRGSVYDAREFSVHFVCGGLAACMATLTVHPVDVLRTRFAAQGEPK 153
Query: 138 I------AVGHQYKHQG 148
+ AVG Y+ +G
Sbjct: 154 VYNTLRHAVGTMYRSEG 170
Score = 31.6 bits (70), Expect = 0.87
Identities = 20/70 (28%), Positives = 33/70 (47%), Gaps = 2/70 (2%)
Query: 17 TNPLEVVKTRMQLQGELQAPGTYQ--RHYRNVFHAFITIGKVDGLAALQKGLAPALLYQF 74
T PL++ K R+Q+ G A + R Y+ + + + +G KGL+P+LL
Sbjct: 234 TYPLDLFKKRLQVGGFEHARAAFGQVRRYKGLMDCAKQVLQKEGALGFFKGLSPSLLKAA 293
Query: 75 LMNGIRLGTY 84
L G +Y
Sbjct: 294 LSTGFMFFSY 303
>gi|86198310 solute carrier family 25, member 29 [Homo sapiens]
Length = 303
Score = 66.6 bits (161), Expect = 2e-11
Identities = 70/252 (27%), Positives = 102/252 (40%), Gaps = 29/252 (11%)
Query: 1 MDFLMSGLAACGACVFTNPLEVVKTRMQLQGELQAPGTYQRHYRNVFHAFITIGKVDGLA 60
+DFL + +P + VK R+Q+Q ++ P YR H F +I K + +
Sbjct: 3 LDFLAGCAGGVAGVLVGHPFDTVKVRLQVQS-VEKP-----QYRGTLHCFKSIIKQESVL 56
Query: 61 ALQKGLAPALLYQFLMNGIRLGTYGLAEAGGYLHTAEGTHSPARSAAAGAMAGVMGAYLG 120
L KGL L+ +N + G G A G SP AGA AG + +
Sbjct: 57 GLYKGLGSPLMGLTFINALVFGVQ------GNTLRALGHDSPLNQFLAGAAAGAIQCVIC 110
Query: 121 SPIYMVKTHLQAQAASEIAVGHQYKHQGMFQALTEIGQKHGLVGLWRGALGGLPRVIVGS 180
P+ + KT LQ Q A G ++G L +I GL G+ RG + L R
Sbjct: 111 CPMELAKTRLQLQDA-----GPARTYKGSLDCLAQIYGHEGLRGVNRGMVSTLLR----E 161
Query: 181 STQLCTFSSTKDLLSQWEIFPPQSWKLA---LVAAMMSGIAVVLAMAPFDVACTRLYNQP 237
+ + T D L++ P L L+A SGI L+ P DV +RL
Sbjct: 162 TPSFGVYFLTYDALTRALGCEPGDRLLVPKLLLAGGTSGIVSWLSTYPVDVVKSRL---- 217
Query: 238 TDAQGKNRVPKF 249
A G P++
Sbjct: 218 -QADGLRGAPRY 228
Score = 35.8 bits (81), Expect = 0.046
Identities = 31/105 (29%), Positives = 43/105 (40%), Gaps = 7/105 (6%)
Query: 4 LMSGLAACGACVFTNPLEVVKTRMQLQGELQAPGTYQRHYRNVFHAFITIGKVDGLAALQ 63
L G + + + T P++VVK+R+Q G AP YR + + +G
Sbjct: 194 LAGGTSGIVSWLSTYPVDVVKSRLQADGLRGAP-----RYRGILDCVHQSYRAEGWRVFT 248
Query: 64 KGLAPALLYQFLMNGIRLGTYG--LAEAGGYLHTAEGTHSPARSA 106
+GLA LL F +N T L A G EG PA A
Sbjct: 249 RGLASTLLRAFPVNAATFATVTVVLTYARGEEAGPEGEAVPAAPA 293
>gi|21314739 solute carrier family 25, member 32 [Homo sapiens]
Length = 315
Score = 65.1 bits (157), Expect = 7e-11
Identities = 67/232 (28%), Positives = 107/232 (46%), Gaps = 30/232 (12%)
Query: 18 NPLEVVKTRMQLQGELQAPGTYQRHYRNVFHAFITIGKVDGLAALQKGLAPAL------- 70
+PL++VK R + L+ + Y + H TI K+DGL L +G+ P +
Sbjct: 41 HPLDLVKIRFAVSDGLEL----RPKYNGILHCLTTIWKLDGLRGLYQGVTPNIWGAGLSW 96
Query: 71 -LYQFLMNGIR-LGTYGLAEAGGYLHTAEGTHSPARSAAAGAMAGVMGAYLGSPIYMVKT 128
LY F N I+ T G AE E T +A AGAM + +P+++ KT
Sbjct: 97 GLYFFFYNAIKSYKTEGRAE------RLEATEYLVSAAEAGAMT----LCITNPLWVTKT 146
Query: 129 HLQAQAASEIAVGHQYKHQGMFQALTEIGQKHGLVGLWRGALGGLPRVIVGSSTQLCTFS 188
L Q + + H+ +++GMF L +I + G+ GL++G + GL G + Q +
Sbjct: 147 RLMLQYDAVVNSPHR-QYKGMFDTLVKIYKYEGVRGLYKGFVPGLFGTSHG-ALQFMAYE 204
Query: 189 STKDLLSQWEIFPPQSWKLALV----AAMMSGIAVVLAMAPFDVACTRLYNQ 236
K +Q P++ +L+ V A +S I V A P+ V RL +Q
Sbjct: 205 LLKLKYNQHINRLPEA-QLSTVEYISVAALSKIFAVAATYPYQVVRARLQDQ 255
Score = 50.8 bits (120), Expect = 1e-06
Identities = 47/180 (26%), Positives = 77/180 (42%), Gaps = 17/180 (9%)
Query: 2 DFLMSGLAACGACVF--TNPLEVVKTRMQLQGELQAPGTYQRHYRNVFHAFITIGKVDGL 59
++L+S A GA TNPL V KTR+ LQ + + R Y+ +F + I K +G+
Sbjct: 122 EYLVSA-AEAGAMTLCITNPLWVTKTRLMLQYDAVVNSPH-RQYKGMFDTLVKIYKYEGV 179
Query: 60 AALQKGLAPALLYQFLMNGIRLGTYGLAEAGGYLH---TAEGTHSPARSAAAGAMAGVMG 116
L KG P L+ ++ Y L + H E S + A++ +
Sbjct: 180 RGLYKGFVPG-LFGTSHGALQFMAYELLKLKYNQHINRLPEAQLSTVEYISVAALSKIFA 238
Query: 117 AYLGSPIYMVKTHLQAQAASEIAVGHQYKHQGMFQALTEIGQKHGLVGLWRGALGGLPRV 176
P +V+ LQ Q H + + G+ +T+ +K G+ G ++G L RV
Sbjct: 239 VAATYPYQVVRARLQDQ--------HMF-YSGVIDVITKTWRKEGVGGFYKGIAPNLIRV 289
>gi|7657581 solute carrier family 25, member 13 isoform 2 [Homo
sapiens]
Length = 675
Score = 64.3 bits (155), Expect = 1e-10
Identities = 54/196 (27%), Positives = 84/196 (42%), Gaps = 20/196 (10%)
Query: 2 DFLMSGLAACGACVFTNPLEVVKTRMQLQGELQAPGTYQRHYRNVFHAFITIGKVDGLAA 61
+ L G A +FTNPLE+VK R+Q+ GE+ + +++ + G
Sbjct: 431 EILAGGCAGGSQVIFTNPLEIVKIRLQVAGEITTGPRV---------SALSVVRDLGFFG 481
Query: 62 LQKGLAPALLYQFLMNGIRLGTYGLAEAGGYLHTAEGTHSPARSAAAGAMAGVMGAYLGS 121
+ KG L + I Y +A +G SP AGA+AG+ A L +
Sbjct: 482 IYKGAKACFLRDIPFSAIYFPCYAHVKAS--FANEDGQVSPGSLLLAGAIAGMPAASLVT 539
Query: 122 PIYMVKTHLQAQAASEIAVGHQYKHQGMFQALTEIGQKHGLVGLWRGALGGLPRVIVGSS 181
P ++KT LQ A + Q + G+ +I ++ G LW+GA + R SS
Sbjct: 540 PADVIKTRLQVAARA-----GQTTYSGVIDCFRKILREEGPKALWKGAGARVFR----SS 590
Query: 182 TQLCTFSSTKDLLSQW 197
Q T +LL +W
Sbjct: 591 PQFGVTLLTYELLQRW 606
Score = 52.0 bits (123), Expect = 6e-07
Identities = 60/235 (25%), Positives = 100/235 (42%), Gaps = 22/235 (9%)
Query: 3 FLMSGLAACGACVFTNPLEVVKTRMQLQGELQAPGTY--QRHYRNVFHAFITIGKVDGLA 60
F + +A P+++VKTRMQ Q ++ G++ + Y+N F F + + +G
Sbjct: 332 FGLGSVAGAVGATAVYPIDLVKTRMQNQ---RSTGSFVGELMYKNSFDCFKKVLRYEGFF 388
Query: 61 ALQKGLAPALLYQFLMNGIRLGTYGLAEAGGYLHTAEGTHSPARSAAAGAMAGVMGAYLG 120
L +GL P LL I+L T ++H +G+ A AG AG
Sbjct: 389 GLYRGLLPQLLGVAPEKAIKL-TVNDFVRDKFMH-KDGSVPLAAEILAGGCAGGSQVIFT 446
Query: 121 SPIYMVKTHLQAQAASEIAVGHQYKHQGMFQALTEIGQKHGLVGLWRGALGGLPRVIVGS 180
+P+ +VK L Q A EI G + + + L G G+++GA R I S
Sbjct: 447 NPLEIVKIRL--QVAGEITTGPRVSALSVVRDL-------GFFGIYKGAKACFLRDIPFS 497
Query: 181 STQLCTFSSTKDLLS--QWEIFPPQSWKLALVAAMMSGIAVVLAMAPFDVACTRL 233
+ ++ K + ++ P L+A ++G+ + P DV TRL
Sbjct: 498 AIYFPCYAHVKASFANEDGQVSPGS----LLLAGAIAGMPAASLVTPADVIKTRL 548
Score = 40.0 bits (92), Expect = 0.002
Identities = 43/183 (23%), Positives = 79/183 (43%), Gaps = 11/183 (6%)
Query: 51 ITIGKVDGLAALQKGLAPALLYQFLMNGIRLGTYGLAEAGGYLHTAEGTHSPARSAAAGA 110
+T+ ++ +A L++G P L + R G + L AE + G+
Sbjct: 285 MTLADIERIAPLEEGTLPFNLAE----AQRQKASGDSARPVLLQVAESAYR----FGLGS 336
Query: 111 MAGVMGAYLGSPIYMVKTHLQAQAASEIAVGHQYKHQGMFQALTEIGQKHGLVGLWRGAL 170
+AG +GA PI +VKT +Q Q ++ VG + ++ F ++ + G GL+RG L
Sbjct: 337 VAGAVGATAVYPIDLVKTRMQNQRSTGSFVG-ELMYKNSFDCFKKVLRYEGFFGLYRGLL 395
Query: 171 GGLPRVIVGSSTQLCTFSSTKDLLSQWEIFPPQSWKLALVAAMMSGIAVVLAMAPFDVAC 230
L V + +L +D + P + ++A +G + V+ P ++
Sbjct: 396 PQLLGVAPEKAIKLTVNDFVRDKFMHKDGSVPLA--AEILAGGCAGGSQVIFTNPLEIVK 453
Query: 231 TRL 233
RL
Sbjct: 454 IRL 456
>gi|237649019 solute carrier family 25, member 13 isoform 1 [Homo
sapiens]
Length = 676
Score = 64.3 bits (155), Expect = 1e-10
Identities = 54/196 (27%), Positives = 84/196 (42%), Gaps = 20/196 (10%)
Query: 2 DFLMSGLAACGACVFTNPLEVVKTRMQLQGELQAPGTYQRHYRNVFHAFITIGKVDGLAA 61
+ L G A +FTNPLE+VK R+Q+ GE+ + +++ + G
Sbjct: 432 EILAGGCAGGSQVIFTNPLEIVKIRLQVAGEITTGPRV---------SALSVVRDLGFFG 482
Query: 62 LQKGLAPALLYQFLMNGIRLGTYGLAEAGGYLHTAEGTHSPARSAAAGAMAGVMGAYLGS 121
+ KG L + I Y +A +G SP AGA+AG+ A L +
Sbjct: 483 IYKGAKACFLRDIPFSAIYFPCYAHVKAS--FANEDGQVSPGSLLLAGAIAGMPAASLVT 540
Query: 122 PIYMVKTHLQAQAASEIAVGHQYKHQGMFQALTEIGQKHGLVGLWRGALGGLPRVIVGSS 181
P ++KT LQ A + Q + G+ +I ++ G LW+GA + R SS
Sbjct: 541 PADVIKTRLQVAARA-----GQTTYSGVIDCFRKILREEGPKALWKGAGARVFR----SS 591
Query: 182 TQLCTFSSTKDLLSQW 197
Q T +LL +W
Sbjct: 592 PQFGVTLLTYELLQRW 607
Score = 52.0 bits (123), Expect = 6e-07
Identities = 60/235 (25%), Positives = 100/235 (42%), Gaps = 22/235 (9%)
Query: 3 FLMSGLAACGACVFTNPLEVVKTRMQLQGELQAPGTY--QRHYRNVFHAFITIGKVDGLA 60
F + +A P+++VKTRMQ Q ++ G++ + Y+N F F + + +G
Sbjct: 333 FGLGSVAGAVGATAVYPIDLVKTRMQNQ---RSTGSFVGELMYKNSFDCFKKVLRYEGFF 389
Query: 61 ALQKGLAPALLYQFLMNGIRLGTYGLAEAGGYLHTAEGTHSPARSAAAGAMAGVMGAYLG 120
L +GL P LL I+L T ++H +G+ A AG AG
Sbjct: 390 GLYRGLLPQLLGVAPEKAIKL-TVNDFVRDKFMH-KDGSVPLAAEILAGGCAGGSQVIFT 447
Query: 121 SPIYMVKTHLQAQAASEIAVGHQYKHQGMFQALTEIGQKHGLVGLWRGALGGLPRVIVGS 180
+P+ +VK L Q A EI G + + + L G G+++GA R I S
Sbjct: 448 NPLEIVKIRL--QVAGEITTGPRVSALSVVRDL-------GFFGIYKGAKACFLRDIPFS 498
Query: 181 STQLCTFSSTKDLLS--QWEIFPPQSWKLALVAAMMSGIAVVLAMAPFDVACTRL 233
+ ++ K + ++ P L+A ++G+ + P DV TRL
Sbjct: 499 AIYFPCYAHVKASFANEDGQVSPGS----LLLAGAIAGMPAASLVTPADVIKTRL 549
Score = 39.7 bits (91), Expect = 0.003
Identities = 45/191 (23%), Positives = 81/191 (42%), Gaps = 26/191 (13%)
Query: 51 ITIGKVDGLAALQKGLAPALLYQFLMNGIRLGTYGLAEAGGYLHTAEGTHSP-----ARS 105
+T+ ++ +A L++G P + LAEA + + P A S
Sbjct: 285 MTLADIERIAPLEEGTLP---------------FNLAEAQRQQKASGDSARPVLLQVAES 329
Query: 106 A---AAGAMAGVMGAYLGSPIYMVKTHLQAQAASEIAVGHQYKHQGMFQALTEIGQKHGL 162
A G++AG +GA PI +VKT +Q Q ++ VG + ++ F ++ + G
Sbjct: 330 AYRFGLGSVAGAVGATAVYPIDLVKTRMQNQRSTGSFVG-ELMYKNSFDCFKKVLRYEGF 388
Query: 163 VGLWRGALGGLPRVIVGSSTQLCTFSSTKDLLSQWEIFPPQSWKLALVAAMMSGIAVVLA 222
GL+RG L L V + +L +D + P + ++A +G + V+
Sbjct: 389 FGLYRGLLPQLLGVAPEKAIKLTVNDFVRDKFMHKDGSVPLA--AEILAGGCAGGSQVIF 446
Query: 223 MAPFDVACTRL 233
P ++ RL
Sbjct: 447 TNPLEIVKIRL 457
>gi|21361103 solute carrier family 25, member 12 [Homo sapiens]
Length = 678
Score = 60.8 bits (146), Expect = 1e-09
Identities = 55/196 (28%), Positives = 80/196 (40%), Gaps = 20/196 (10%)
Query: 2 DFLMSGLAACGACVFTNPLEVVKTRMQLQGELQAPGTYQRHYRNVFHAFITIGKVDGLAA 61
+ L G A +FTNPLE+VK R+Q+ GE+ + + + + G+
Sbjct: 429 EVLAGGCAGGSQVIFTNPLEIVKIRLQVAGEITTGPRV---------SALNVLRDLGIFG 479
Query: 62 LQKGLAPALLYQFLMNGIRLGTYGLAEAGGYLHTAEGTHSPARSAAAGAMAGVMGAYLGS 121
L KG L + I Y A L G AAGAMAGV A L +
Sbjct: 480 LYKGAKACFLRDIPFSAIYFPVY--AHCKLLLADENGHVGGLNLLAAGAMAGVPAASLVT 537
Query: 122 PIYMVKTHLQAQAASEIAVGHQYKHQGMFQALTEIGQKHGLVGLWRGALGGLPRVIVGSS 181
P ++KT LQ A + Q + G+ +I ++ G W+G + R SS
Sbjct: 538 PADVIKTRLQVAARA-----GQTTYSGVIDCFRKILREEGPSAFWKGTAARVFR----SS 588
Query: 182 TQLCTFSSTKDLLSQW 197
Q T +LL +W
Sbjct: 589 PQFGVTLVTYELLQRW 604
Score = 52.4 bits (124), Expect = 5e-07
Identities = 62/232 (26%), Positives = 92/232 (39%), Gaps = 16/232 (6%)
Query: 3 FLMSGLAACGACVFTNPLEVVKTRMQLQ-GELQAPGTYQRHYRNVFHAFITIGKVDGLAA 61
F + +A P+++VKTRMQ Q G G Y+N F F + + +G
Sbjct: 330 FTLGSVAGAVGATAVYPIDLVKTRMQNQRGSGSVVGELM--YKNSFDCFKKVLRYEGFFG 387
Query: 62 LQKGLAPALLYQFLMNGIRLGTYGLAEAGGYLHTAEGTHSPARSAAAGAMAGVMGAYLGS 121
L +GL P L+ I+L +G+ AG AG +
Sbjct: 388 LYRGLIPQLIGVAPEKAIKLTVNDFVR--DKFTRRDGSVPLPAEVLAGGCAGGSQVIFTN 445
Query: 122 PIYMVKTHLQAQAASEIAVGHQYKHQGMFQALTEIGQKHGLVGLWRGALGGLPRVIVGSS 181
P+ +VK L Q A EI G + + + L G+ GL++GA R I S+
Sbjct: 446 PLEIVKIRL--QVAGEITTGPRVSALNVLRDL-------GIFGLYKGAKACFLRDIPFSA 496
Query: 182 TQLCTFSSTKDLLSQWEIFPPQSWKLALVAAMMSGIAVVLAMAPFDVACTRL 233
++ K LL+ E L L A M+G+ + P DV TRL
Sbjct: 497 IYFPVYAHCKLLLAD-ENGHVGGLNL-LAAGAMAGVPAASLVTPADVIKTRL 546
Score = 40.0 bits (92), Expect = 0.002
Identities = 44/183 (24%), Positives = 80/183 (43%), Gaps = 12/183 (6%)
Query: 51 ITIGKVDGLAALQKGLAPALLYQFLMNGIRLGTYGLAEAGGYLHTAEGTHSPARSAAAGA 110
+T+ ++ +A L +G P L + R + GL +L AE + G+
Sbjct: 284 LTLADIERIAPLAEGALPYNLAELQ----RQQSPGLGRPI-WLQIAESAYR----FTLGS 334
Query: 111 MAGVMGAYLGSPIYMVKTHLQAQAASEIAVGHQYKHQGMFQALTEIGQKHGLVGLWRGAL 170
+AG +GA PI +VKT +Q Q S VG + ++ F ++ + G GL+RG +
Sbjct: 335 VAGAVGATAVYPIDLVKTRMQNQRGSGSVVG-ELMYKNSFDCFKKVLRYEGFFGLYRGLI 393
Query: 171 GGLPRVIVGSSTQLCTFSSTKDLLSQWEIFPPQSWKLALVAAMMSGIAVVLAMAPFDVAC 230
L V + +L +D ++ + P ++A +G + V+ P ++
Sbjct: 394 PQLIGVAPEKAIKLTVNDFVRDKFTRRDGSVP--LPAEVLAGGCAGGSQVIFTNPLEIVK 451
Query: 231 TRL 233
RL
Sbjct: 452 IRL 454
>gi|148491091 solute carrier family 25 member 24 isoform 1 [Homo
sapiens]
Length = 477
Score = 59.7 bits (143), Expect = 3e-09
Identities = 53/194 (27%), Positives = 82/194 (42%), Gaps = 15/194 (7%)
Query: 3 FLMSGLAACGACVFTNPLEVVKTRMQLQGELQAPGTYQRHYRNVFHAFITIGKVDGLAAL 62
F+ +A A F P+EV+KTR+ + Q Y ++ I K +GL A
Sbjct: 292 FISGSMAGATAQTFIYPMEVMKTRLAVGKTGQ--------YSGIYDCAKKILKHEGLGAF 343
Query: 63 QKGLAPALLYQFLMNGIRLGTYGLAEAGGYLHTAEGTHSPARSA--AAGAMAGVMGAYLG 120
KG P LL GI L Y L ++ + A+ + +P GA++ G
Sbjct: 344 YKGYVPNLLGIIPYAGIDLAVYELLKSYWLDNFAKDSVNPGVMVLLGCGALSSTCGQLAS 403
Query: 121 SPIYMVKTHLQAQAASEIAVGHQYKHQGMFQALTEIGQKHGLVGLWRGALGGLPRVIVGS 180
P+ +V+T +QAQA E Q G+F+ I K G+ GL+RG +V+
Sbjct: 404 YPLALVRTRMQAQAMLE--GSPQLNMVGLFR---RIISKEGIPGLYRGITPNFMKVLPAV 458
Query: 181 STQLCTFSSTKDLL 194
+ + K L
Sbjct: 459 GISYVVYENMKQTL 472
Score = 39.7 bits (91), Expect = 0.003
Identities = 53/236 (22%), Positives = 91/236 (38%), Gaps = 31/236 (13%)
Query: 4 LMSGLAACGACVFTNPLEVVKTRMQLQGELQAPGTYQRHYRNVFHAFITIGKVDGLAALQ 63
L G+A + T PL+ +K MQ+ G + N+F F + K G+ +L
Sbjct: 199 LAGGIAGAVSRTSTAPLDRLKIMMQVHGS-------KSDKMNIFGGFRQMVKEGGIRSLW 251
Query: 64 KGLAPALLYQFLMNGIRLGTYGLAEAGGYLHTAEGTH-SPARSAAAGAMAGVMGAYLGSP 122
+G ++ ++ Y E L T EG +G+MAG P
Sbjct: 252 RGNGTNVIKIAPETAVKFWAY---EQYKKLLTEEGQKIGTFERFISGSMAGATAQTFIYP 308
Query: 123 IYMVKTHLQAQAASEIAVGHQYKHQGMFQALTEIGQKHGLVGLWRGALGGLPRVIVGSST 182
+ ++KT L AVG ++ G++ +I + GL ++G + L +I +
Sbjct: 309 MEVMKTRL--------AVGKTGQYSGIYDCAKKILKHEGLGAFYKGYVPNLLGIIPYAGI 360
Query: 183 QLCTFSSTKDLLSQW-EIFPPQSWKLALVAAMMSGIAVVLAMAPFDVACTRLYNQP 237
L + K S W + F S + G+ V+L C +L + P
Sbjct: 361 DLAVYELLK---SYWLDNFAKDS--------VNPGVMVLLGCGALSSTCGQLASYP 405
>gi|47458041 solute carrier family 25 member 24 isoform 2 [Homo
sapiens]
Length = 458
Score = 59.7 bits (143), Expect = 3e-09
Identities = 53/194 (27%), Positives = 82/194 (42%), Gaps = 15/194 (7%)
Query: 3 FLMSGLAACGACVFTNPLEVVKTRMQLQGELQAPGTYQRHYRNVFHAFITIGKVDGLAAL 62
F+ +A A F P+EV+KTR+ + Q Y ++ I K +GL A
Sbjct: 273 FISGSMAGATAQTFIYPMEVMKTRLAVGKTGQ--------YSGIYDCAKKILKHEGLGAF 324
Query: 63 QKGLAPALLYQFLMNGIRLGTYGLAEAGGYLHTAEGTHSPARSA--AAGAMAGVMGAYLG 120
KG P LL GI L Y L ++ + A+ + +P GA++ G
Sbjct: 325 YKGYVPNLLGIIPYAGIDLAVYELLKSYWLDNFAKDSVNPGVMVLLGCGALSSTCGQLAS 384
Query: 121 SPIYMVKTHLQAQAASEIAVGHQYKHQGMFQALTEIGQKHGLVGLWRGALGGLPRVIVGS 180
P+ +V+T +QAQA E Q G+F+ I K G+ GL+RG +V+
Sbjct: 385 YPLALVRTRMQAQAMLE--GSPQLNMVGLFR---RIISKEGIPGLYRGITPNFMKVLPAV 439
Query: 181 STQLCTFSSTKDLL 194
+ + K L
Sbjct: 440 GISYVVYENMKQTL 453
Score = 39.7 bits (91), Expect = 0.003
Identities = 53/236 (22%), Positives = 91/236 (38%), Gaps = 31/236 (13%)
Query: 4 LMSGLAACGACVFTNPLEVVKTRMQLQGELQAPGTYQRHYRNVFHAFITIGKVDGLAALQ 63
L G+A + T PL+ +K MQ+ G + N+F F + K G+ +L
Sbjct: 180 LAGGIAGAVSRTSTAPLDRLKIMMQVHGS-------KSDKMNIFGGFRQMVKEGGIRSLW 232
Query: 64 KGLAPALLYQFLMNGIRLGTYGLAEAGGYLHTAEGTH-SPARSAAAGAMAGVMGAYLGSP 122
+G ++ ++ Y E L T EG +G+MAG P
Sbjct: 233 RGNGTNVIKIAPETAVKFWAY---EQYKKLLTEEGQKIGTFERFISGSMAGATAQTFIYP 289
Query: 123 IYMVKTHLQAQAASEIAVGHQYKHQGMFQALTEIGQKHGLVGLWRGALGGLPRVIVGSST 182
+ ++KT L AVG ++ G++ +I + GL ++G + L +I +
Sbjct: 290 MEVMKTRL--------AVGKTGQYSGIYDCAKKILKHEGLGAFYKGYVPNLLGIIPYAGI 341
Query: 183 QLCTFSSTKDLLSQW-EIFPPQSWKLALVAAMMSGIAVVLAMAPFDVACTRLYNQP 237
L + K S W + F S + G+ V+L C +L + P
Sbjct: 342 DLAVYELLK---SYWLDNFAKDS--------VNPGVMVLLGCGALSSTCGQLASYP 386
>gi|27544933 solute carrier family 25, member 16 [Homo sapiens]
Length = 332
Score = 56.2 bits (134), Expect = 3e-08
Identities = 40/130 (30%), Positives = 59/130 (45%), Gaps = 9/130 (6%)
Query: 104 RSAAAGAMAGVMGAYLGSPIYMVKTHLQAQAASEIAVGHQYKHQGMFQALTEIGQKHGLV 163
RS AG +AG +P+ VK LQA H YKH G+F AL + QK G +
Sbjct: 38 RSFLAGGIAGCCAKTTVAPLDRVKVLLQAH-------NHHYKHLGVFSALRAVPQKEGFL 90
Query: 164 GLWRGALGGLPRVIVGSSTQLCTFSSTKDLLSQWEIFPPQSWKLALVAAMMSGIAVVLAM 223
GL++G + R+ + Q F K L++ + L+A M+G+ V+
Sbjct: 91 GLYKGNGAMMIRIFPYGAIQFMAFEHYKTLITTKLGISGHVHR--LMAGSMAGMTAVICT 148
Query: 224 APFDVACTRL 233
P D+ RL
Sbjct: 149 YPLDMVRVRL 158
Score = 48.5 bits (114), Expect = 7e-06
Identities = 49/200 (24%), Positives = 76/200 (38%), Gaps = 32/200 (16%)
Query: 3 FLMSGLAACGACVFTNPLEVVKTRMQLQGELQAPGTYQRHYRN--VFHAFITIGKVDGLA 60
FL G+A C A PL+ VK +Q + HY++ VF A + + +G
Sbjct: 40 FLAGGIAGCCAKTTVAPLDRVKVLLQ---------AHNHHYKHLGVFSALRAVPQKEGFL 90
Query: 61 ALQKGLAPALLYQFLMNGIRLGTYGLAEAGGYLH------TAEGTHSPARSAAAGAMAGV 114
L KG + IR+ YG + + H T G AG+MAG+
Sbjct: 91 GLYKGNGAMM--------IRIFPYGAIQFMAFEHYKTLITTKLGISGHVHRLMAGSMAGM 142
Query: 115 MGAYLGSPIYMVKTHLQAQAASEIAVGHQYKHQGMFQALTEIGQKH-GLVGLWRGALGGL 173
P+ MV+ L Q E + + G+ A I K G G +RG + +
Sbjct: 143 TAVICTYPLDMVRVRLAFQVKGE------HSYTGIIHAFKTIYAKEGGFFGFYRGLMPTI 196
Query: 174 PRVIVGSSTQLCTFSSTKDL 193
+ + TF + K +
Sbjct: 197 LGMAPYAGVSFFTFGTLKSV 216
Score = 40.8 bits (94), Expect = 0.001
Identities = 48/205 (23%), Positives = 79/205 (38%), Gaps = 29/205 (14%)
Query: 4 LMSG-LAACGACVFTNPLEVVKTRM--QLQGELQAPGTYQRHYRNVFHAFITI-GKVDGL 59
LM+G +A A + T PL++V+ R+ Q++GE Y + HAF TI K G
Sbjct: 134 LMAGSMAGMTAVICTYPLDMVRVRLAFQVKGE--------HSYTGIIHAFKTIYAKEGGF 185
Query: 60 AALQKGLAPALLYQFLMNGIRLGTYGLAEAGGYLHTAEGTHSPAR------------SAA 107
+GL P +L G+ T+G ++ G H P+ +
Sbjct: 186 FGFYRGLMPTILGMAPYAGVSFFTFGTLKSVGLSHAPTLLGRPSSDNPNVLVLKTHVNLL 245
Query: 108 AGAMAGVMGAYLGSPIYMVKTHLQAQAASEIAVGHQYKHQGMFQALTEIGQKHGL-VGLW 166
G +AG + + P + + +Q + K M + + HG+ GL+
Sbjct: 246 CGGVAGAIAQTISYPFDVTRRRMQLGT----VLPEFEKCLTMRDTMKYVYGHHGIRKGLY 301
Query: 167 RGALGGLPRVIVGSSTQLCTFSSTK 191
RG R I + T+ K
Sbjct: 302 RGLSLNYIRCIPSQAVAFTTYELMK 326
>gi|60460887 solute carrier family 25, member 42 [Homo sapiens]
Length = 318
Score = 54.7 bits (130), Expect = 1e-07
Identities = 43/162 (26%), Positives = 70/162 (43%), Gaps = 15/162 (9%)
Query: 8 LAACGACVFTNPLEVVKTRMQLQGELQAPGTYQRHYRNVFHAFITIGKVDGLAALQKGLA 67
LA A T PL++V+ RM + T + Y N+FH FI I + +GL L G
Sbjct: 140 LAGTTAASLTYPLDLVRARMAV--------TPKEMYSNIFHVFIRISREEGLKTLYHGFM 191
Query: 68 PALLYQFLMNGIRLGTYGLAEAGGYLHTAEGTHSPARSAAAGAMAGVMGAYLGSPIYMVK 127
P +L G+ TY ++ ++ P GA AG++G P+ +V+
Sbjct: 192 PTVLGVIPYAGLSFFTYETLKSLHREYSGRRQPYPFERMIFGACAGLIGQSASYPLDVVR 251
Query: 128 THLQAQAASEIAVGHQYKHQGMFQALTEIGQKHGLV-GLWRG 168
+Q + Y + + L I ++ G V GL++G
Sbjct: 252 RRMQTAGVT------GYPRASIARTLRTIVREEGAVRGLYKG 287
Score = 33.5 bits (75), Expect = 0.23
Identities = 39/173 (22%), Positives = 65/173 (37%), Gaps = 20/173 (11%)
Query: 77 NGIRLGTYGLAE-AGGYLHTAEGTHSPAR----SAAAGAMAGVMGAYLGSPIYMVKTHLQ 131
NG++ G L E A L ++ + R S GA+AG + +P+ K Q
Sbjct: 3 NGVKEGPVRLHEDAEAVLSSSVSSKRDHRQVLSSLLPGALAGALAKTAVAPLDRTKIIFQ 62
Query: 132 AQAASEIAVGHQYKHQGMFQALTEIGQKHGLVGLWRGALGGLPRVIVGSSTQLCTFSSTK 191
+ ++ + F+ L G + LWRG + RV+ ++ Q K
Sbjct: 63 VSSK-------RFSAKEAFRVLYYTYLNEGFLSLWRGNSATMVRVVPYAAIQFSAHEEYK 115
Query: 192 DLLSQW-----EIFPPQSWKLALVAAMMSGIAVVLAMAPFDVACTRLYNQPTD 239
+L + E PP W L A ++G P D+ R+ P +
Sbjct: 116 RILGSYYGFRGEALPP--WP-RLFAGALAGTTAASLTYPLDLVRARMAVTPKE 165
>gi|239755176 PREDICTED: similar to solute carrier family 25, member
25 isoform 2 [Homo sapiens]
Length = 469
Score = 54.7 bits (130), Expect = 1e-07
Identities = 50/179 (27%), Positives = 72/179 (40%), Gaps = 23/179 (12%)
Query: 19 PLEVVKTRMQLQGELQAPGTYQRHYRNVFHAFITIGKVDGLAALQKGLAPALLYQFLMNG 78
P+EV+KTRM L+ Q Y + I +G+AA KG P +L G
Sbjct: 300 PMEVLKTRMALRKTGQ--------YSGMLDCARRILAREGVAAFYKGYVPNMLGIIPYAG 351
Query: 79 IRLGTYGLAEAGGYLHTAEGTHSPARSA--AAGAMAGVMGAYLGSPIYMVKTHLQAQA-- 134
I L Y + H A + P A G M+ G P+ +V+T +QAQA
Sbjct: 352 IDLAVYETLKNAWLQHYAVNSADPGVFVLLACGTMSSTCGQLASYPLALVRTRMQAQASI 411
Query: 135 --ASEIAVGHQYKHQGMFQALTEIGQKHGLVGLWRGALGGLPRVIVGSSTQLCTFSSTK 191
A E+ + +KH I + G GL+RG +VI S + + K
Sbjct: 412 EGAPEVTMSSLFKH---------ILRTEGAFGLYRGLAPNFMKVIPAVSISYVVYENLK 461
>gi|239755174 PREDICTED: similar to solute carrier family 25, member
25 isoform 1 [Homo sapiens]
Length = 503
Score = 54.7 bits (130), Expect = 1e-07
Identities = 50/179 (27%), Positives = 72/179 (40%), Gaps = 23/179 (12%)
Query: 19 PLEVVKTRMQLQGELQAPGTYQRHYRNVFHAFITIGKVDGLAALQKGLAPALLYQFLMNG 78
P+EV+KTRM L+ Q Y + I +G+AA KG P +L G
Sbjct: 334 PMEVLKTRMALRKTGQ--------YSGMLDCARRILAREGVAAFYKGYVPNMLGIIPYAG 385
Query: 79 IRLGTYGLAEAGGYLHTAEGTHSPARSA--AAGAMAGVMGAYLGSPIYMVKTHLQAQA-- 134
I L Y + H A + P A G M+ G P+ +V+T +QAQA
Sbjct: 386 IDLAVYETLKNAWLQHYAVNSADPGVFVLLACGTMSSTCGQLASYPLALVRTRMQAQASI 445
Query: 135 --ASEIAVGHQYKHQGMFQALTEIGQKHGLVGLWRGALGGLPRVIVGSSTQLCTFSSTK 191
A E+ + +KH I + G GL+RG +VI S + + K
Sbjct: 446 EGAPEVTMSSLFKH---------ILRTEGAFGLYRGLAPNFMKVIPAVSISYVVYENLK 495
>gi|56699407 solute carrier family 25, member 25 isoform c [Homo
sapiens]
Length = 489
Score = 54.7 bits (130), Expect = 1e-07
Identities = 50/179 (27%), Positives = 72/179 (40%), Gaps = 23/179 (12%)
Query: 19 PLEVVKTRMQLQGELQAPGTYQRHYRNVFHAFITIGKVDGLAALQKGLAPALLYQFLMNG 78
P+EV+KTRM L+ Q Y + I +G+AA KG P +L G
Sbjct: 320 PMEVLKTRMALRKTGQ--------YSGMLDCARRILAREGVAAFYKGYVPNMLGIIPYAG 371
Query: 79 IRLGTYGLAEAGGYLHTAEGTHSPARSA--AAGAMAGVMGAYLGSPIYMVKTHLQAQA-- 134
I L Y + H A + P A G M+ G P+ +V+T +QAQA
Sbjct: 372 IDLAVYETLKNAWLQHYAVNSADPGVFVLLACGTMSSTCGQLASYPLALVRTRMQAQASI 431
Query: 135 --ASEIAVGHQYKHQGMFQALTEIGQKHGLVGLWRGALGGLPRVIVGSSTQLCTFSSTK 191
A E+ + +KH I + G GL+RG +VI S + + K
Sbjct: 432 EGAPEVTMSSLFKH---------ILRTEGAFGLYRGLAPNFMKVIPAVSISYVVYENLK 481
>gi|56699401 solute carrier family 25, member 25 isoform a [Homo
sapiens]
Length = 469
Score = 54.7 bits (130), Expect = 1e-07
Identities = 50/179 (27%), Positives = 72/179 (40%), Gaps = 23/179 (12%)
Query: 19 PLEVVKTRMQLQGELQAPGTYQRHYRNVFHAFITIGKVDGLAALQKGLAPALLYQFLMNG 78
P+EV+KTRM L+ Q Y + I +G+AA KG P +L G
Sbjct: 300 PMEVLKTRMALRKTGQ--------YSGMLDCARRILAREGVAAFYKGYVPNMLGIIPYAG 351
Query: 79 IRLGTYGLAEAGGYLHTAEGTHSPARSA--AAGAMAGVMGAYLGSPIYMVKTHLQAQA-- 134
I L Y + H A + P A G M+ G P+ +V+T +QAQA
Sbjct: 352 IDLAVYETLKNAWLQHYAVNSADPGVFVLLACGTMSSTCGQLASYPLALVRTRMQAQASI 411
Query: 135 --ASEIAVGHQYKHQGMFQALTEIGQKHGLVGLWRGALGGLPRVIVGSSTQLCTFSSTK 191
A E+ + +KH I + G GL+RG +VI S + + K
Sbjct: 412 EGAPEVTMSSLFKH---------ILRTEGAFGLYRGLAPNFMKVIPAVSISYVVYENLK 461
>gi|56699405 solute carrier family 25, member 25 isoform d [Homo
sapiens]
Length = 366
Score = 54.7 bits (130), Expect = 1e-07
Identities = 50/179 (27%), Positives = 72/179 (40%), Gaps = 23/179 (12%)
Query: 19 PLEVVKTRMQLQGELQAPGTYQRHYRNVFHAFITIGKVDGLAALQKGLAPALLYQFLMNG 78
P+EV+KTRM L+ Q Y + I +G+AA KG P +L G
Sbjct: 197 PMEVLKTRMALRKTGQ--------YSGMLDCARRILAREGVAAFYKGYVPNMLGIIPYAG 248
Query: 79 IRLGTYGLAEAGGYLHTAEGTHSPARSA--AAGAMAGVMGAYLGSPIYMVKTHLQAQA-- 134
I L Y + H A + P A G M+ G P+ +V+T +QAQA
Sbjct: 249 IDLAVYETLKNAWLQHYAVNSADPGVFVLLACGTMSSTCGQLASYPLALVRTRMQAQASI 308
Query: 135 --ASEIAVGHQYKHQGMFQALTEIGQKHGLVGLWRGALGGLPRVIVGSSTQLCTFSSTK 191
A E+ + +KH I + G GL+RG +VI S + + K
Sbjct: 309 EGAPEVTMSSLFKH---------ILRTEGAFGLYRGLAPNFMKVIPAVSISYVVYENLK 358
>gi|56699403 solute carrier family 25, member 25 isoform b [Homo
sapiens]
Length = 503
Score = 54.7 bits (130), Expect = 1e-07
Identities = 50/179 (27%), Positives = 72/179 (40%), Gaps = 23/179 (12%)
Query: 19 PLEVVKTRMQLQGELQAPGTYQRHYRNVFHAFITIGKVDGLAALQKGLAPALLYQFLMNG 78
P+EV+KTRM L+ Q Y + I +G+AA KG P +L G
Sbjct: 334 PMEVLKTRMALRKTGQ--------YSGMLDCARRILAREGVAAFYKGYVPNMLGIIPYAG 385
Query: 79 IRLGTYGLAEAGGYLHTAEGTHSPARSA--AAGAMAGVMGAYLGSPIYMVKTHLQAQA-- 134
I L Y + H A + P A G M+ G P+ +V+T +QAQA
Sbjct: 386 IDLAVYETLKNAWLQHYAVNSADPGVFVLLACGTMSSTCGQLASYPLALVRTRMQAQASI 445
Query: 135 --ASEIAVGHQYKHQGMFQALTEIGQKHGLVGLWRGALGGLPRVIVGSSTQLCTFSSTK 191
A E+ + +KH I + G GL+RG +VI S + + K
Sbjct: 446 EGAPEVTMSSLFKH---------ILRTEGAFGLYRGLAPNFMKVIPAVSISYVVYENLK 495
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.321 0.134 0.405
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 10,917,280
Number of Sequences: 37866
Number of extensions: 446037
Number of successful extensions: 1300
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 34
Number of HSP's successfully gapped in prelim test: 37
Number of HSP's that attempted gapping in prelim test: 1021
Number of HSP's gapped (non-prelim): 167
length of query: 295
length of database: 18,247,518
effective HSP length: 102
effective length of query: 193
effective length of database: 14,385,186
effective search space: 2776340898
effective search space used: 2776340898
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.