Guide to the Human Genome
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Search of human proteins with 41393547

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|41393547 neuroblastoma-amplified protein [Homo sapiens]
         (2371 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|41393547 neuroblastoma-amplified protein [Homo sapiens]           4763   0.0  
gi|50658069 phosphodiesterase 4D interacting protein isoform 2 [...    37   0.18 
gi|50658071 phosphodiesterase 4D interacting protein isoform 5 [...    37   0.18 
gi|157311604 phosphodiesterase 4D interacting protein isoform 1 ...    37   0.18 
gi|4503179 oral-facial-digital syndrome 1 [Homo sapiens]               36   0.39 
gi|56550047 uveal autoantigen with coiled-coil domains and ankyr...    36   0.51 
gi|59850762 uveal autoantigen with coiled-coil domains and ankyr...    36   0.51 
gi|7661960 Rough Deal homolog, centromere/kinetochore protein [H...    35   0.88 
gi|186928844 Cdc42 GTPase-activating protein [Homo sapiens]            35   1.1  
gi|55956890 kelch/ankyrin repeat containing cyclin A1 interactin...    35   1.1  
gi|55956888 kelch/ankyrin repeat containing cyclin A1 interactin...    35   1.1  
gi|169217489 PREDICTED: similar to phosphodiesterase 4D interact...    34   1.5  
gi|50658077 phosphodiesterase 4D interacting protein isoform 4 [...    34   2.0  
gi|50658075 phosphodiesterase 4D interacting protein isoform 3 [...    34   2.0  
gi|195976782 Paf1/RNA polymerase II complex component [Homo sapi...    34   2.0  
gi|34222391 zinc finger protein 605 [Homo sapiens]                     34   2.0  
gi|223005859 WD repeat domain 67 isoform 1 [Homo sapiens]              33   2.6  
gi|223005857 WD repeat domain 67 isoform 2 [Homo sapiens]              33   2.6  
gi|94538370 DnaJ (Hsp40) homolog, subfamily C, member 2 isoform ...    33   2.6  
gi|7662386 NLR family, pyrin domain containing 1 isoform 2 [Homo...    33   4.4  
gi|14719835 NLR family, pyrin domain containing 1 isoform 4 [Hom...    33   4.4  
gi|74271814 NLR family, pyrin domain containing 1 isoform 5 [Hom...    33   4.4  
gi|14719833 NLR family, pyrin domain containing 1 isoform 3 [Hom...    33   4.4  
gi|14719829 NLR family, pyrin domain containing 1 isoform 1 [Hom...    33   4.4  
gi|155030226 phosphatidylinositol 4-kinase type 3 alpha isoform ...    33   4.4  
gi|199559532 Abelson helper integration site 1 isoform b [Homo s...    33   4.4  
gi|199559490 Abelson helper integration site 1 isoform a [Homo s...    33   4.4  
gi|199559438 Abelson helper integration site 1 isoform a [Homo s...    33   4.4  
gi|31542701 Abelson helper integration site 1 isoform a [Homo sa...    33   4.4  
gi|24308069 zinc finger protein 521 [Homo sapiens]                     33   4.4  

>gi|41393547 neuroblastoma-amplified protein [Homo sapiens]
          Length = 2371

 Score = 4763 bits (12355), Expect = 0.0
 Identities = 2371/2371 (100%), Positives = 2371/2371 (100%)

Query: 1    MAAPESGPALSPGTAEGEEETILYDLLVNTEWPPETEVQPRGNQKHGASFIITKAIRDRL 60
            MAAPESGPALSPGTAEGEEETILYDLLVNTEWPPETEVQPRGNQKHGASFIITKAIRDRL
Sbjct: 1    MAAPESGPALSPGTAEGEEETILYDLLVNTEWPPETEVQPRGNQKHGASFIITKAIRDRL 60

Query: 61   LFLRQYIWYSPAPFLLPDGLVRLVNKQINWHLVLASNGKLLAAVQDQCVEIRSAKDDFTS 120
            LFLRQYIWYSPAPFLLPDGLVRLVNKQINWHLVLASNGKLLAAVQDQCVEIRSAKDDFTS
Sbjct: 61   LFLRQYIWYSPAPFLLPDGLVRLVNKQINWHLVLASNGKLLAAVQDQCVEIRSAKDDFTS 120

Query: 121  IIGKCQVPKDPKPQWRRVAWSYDCTLLAYAESTGTVRVFDLMGSELFVISPASSFIGDLS 180
            IIGKCQVPKDPKPQWRRVAWSYDCTLLAYAESTGTVRVFDLMGSELFVISPASSFIGDLS
Sbjct: 121  IIGKCQVPKDPKPQWRRVAWSYDCTLLAYAESTGTVRVFDLMGSELFVISPASSFIGDLS 180

Query: 181  YAIAGLIFLEYKASAQWSAELLVINYRGELRSYLVSVGTNQSYQESHCFSFSSHYPHGIN 240
            YAIAGLIFLEYKASAQWSAELLVINYRGELRSYLVSVGTNQSYQESHCFSFSSHYPHGIN
Sbjct: 181  YAIAGLIFLEYKASAQWSAELLVINYRGELRSYLVSVGTNQSYQESHCFSFSSHYPHGIN 240

Query: 241  TAIYHPGHRLLLVGGCETAEVGMSKASSCGLSAWRVLSGSPYYKQVTNGGDGVTAVPKTL 300
            TAIYHPGHRLLLVGGCETAEVGMSKASSCGLSAWRVLSGSPYYKQVTNGGDGVTAVPKTL
Sbjct: 241  TAIYHPGHRLLLVGGCETAEVGMSKASSCGLSAWRVLSGSPYYKQVTNGGDGVTAVPKTL 300

Query: 301  GLLRMLSVKFYSRQGQEQDGIFKMSLSPDGMLLAAIHFSGKLSIWAIPSLKQQGEWGQNE 360
            GLLRMLSVKFYSRQGQEQDGIFKMSLSPDGMLLAAIHFSGKLSIWAIPSLKQQGEWGQNE
Sbjct: 301  GLLRMLSVKFYSRQGQEQDGIFKMSLSPDGMLLAAIHFSGKLSIWAIPSLKQQGEWGQNE 360

Query: 361  QPGYDDLNPDWRLSTEKRKKIKDKESFYPLIDVNWWADSAVTLARCSGALTVSSVKTLKN 420
            QPGYDDLNPDWRLSTEKRKKIKDKESFYPLIDVNWWADSAVTLARCSGALTVSSVKTLKN
Sbjct: 361  QPGYDDLNPDWRLSTEKRKKIKDKESFYPLIDVNWWADSAVTLARCSGALTVSSVKTLKN 420

Query: 421  LLGKSCEWFEPSPQVTATHDGGFLSLECEIKLAPKRSRLETRAGEEDEGEEDSDSDYEIS 480
            LLGKSCEWFEPSPQVTATHDGGFLSLECEIKLAPKRSRLETRAGEEDEGEEDSDSDYEIS
Sbjct: 421  LLGKSCEWFEPSPQVTATHDGGFLSLECEIKLAPKRSRLETRAGEEDEGEEDSDSDYEIS 480

Query: 481  AKARYFGYIKQGLYLVTEMERFAPPRKRPRTITKNYRLVSLRSTTPEELYQRKIESEEYE 540
            AKARYFGYIKQGLYLVTEMERFAPPRKRPRTITKNYRLVSLRSTTPEELYQRKIESEEYE
Sbjct: 481  AKARYFGYIKQGLYLVTEMERFAPPRKRPRTITKNYRLVSLRSTTPEELYQRKIESEEYE 540

Query: 541  EALSLAHTYGLDTDLVYQRQWRKSAVNVASIQNYLSKIKKRSWVLHECLERVPENVDAAK 600
            EALSLAHTYGLDTDLVYQRQWRKSAVNVASIQNYLSKIKKRSWVLHECLERVPENVDAAK
Sbjct: 541  EALSLAHTYGLDTDLVYQRQWRKSAVNVASIQNYLSKIKKRSWVLHECLERVPENVDAAK 600

Query: 601  ELLQYGLKGTDLEALLAIGKGADDGRFTLPGEIDIDSISYEELSPPDEEPAKNKKEKELK 660
            ELLQYGLKGTDLEALLAIGKGADDGRFTLPGEIDIDSISYEELSPPDEEPAKNKKEKELK
Sbjct: 601  ELLQYGLKGTDLEALLAIGKGADDGRFTLPGEIDIDSISYEELSPPDEEPAKNKKEKELK 660

Query: 661  KRQELLKLVNFSKLTLEQKELCRCRRKLLTYLDRLATYEEILGVPHASEQRYDAEFFKKF 720
            KRQELLKLVNFSKLTLEQKELCRCRRKLLTYLDRLATYEEILGVPHASEQRYDAEFFKKF
Sbjct: 661  KRQELLKLVNFSKLTLEQKELCRCRRKLLTYLDRLATYEEILGVPHASEQRYDAEFFKKF 720

Query: 721  RNQNIVLSARTYAQESNVQALEILFTYHGSDLLPHRLAILSNFPETTSPHEYSVLLPEAC 780
            RNQNIVLSARTYAQESNVQALEILFTYHGSDLLPHRLAILSNFPETTSPHEYSVLLPEAC
Sbjct: 721  RNQNIVLSARTYAQESNVQALEILFTYHGSDLLPHRLAILSNFPETTSPHEYSVLLPEAC 780

Query: 781  FNGDSLMIIPWHEHKHRAKDWCEELACRMVVEPNLQDESEFLYAAQPELLRFRMTQLTVE 840
            FNGDSLMIIPWHEHKHRAKDWCEELACRMVVEPNLQDESEFLYAAQPELLRFRMTQLTVE
Sbjct: 781  FNGDSLMIIPWHEHKHRAKDWCEELACRMVVEPNLQDESEFLYAAQPELLRFRMTQLTVE 840

Query: 841  KVMDWYQTRAEEIEHYARQVDCALSLIRLGMERNIPGLLVLCDNLVTLETLVYEARCDVT 900
            KVMDWYQTRAEEIEHYARQVDCALSLIRLGMERNIPGLLVLCDNLVTLETLVYEARCDVT
Sbjct: 841  KVMDWYQTRAEEIEHYARQVDCALSLIRLGMERNIPGLLVLCDNLVTLETLVYEARCDVT 900

Query: 901  LTLKELQQMKDIEKLRLLMNSCSEDKYVTSAYQWMVPFLHRCEKQSPGVANELLKEYLVT 960
            LTLKELQQMKDIEKLRLLMNSCSEDKYVTSAYQWMVPFLHRCEKQSPGVANELLKEYLVT
Sbjct: 901  LTLKELQQMKDIEKLRLLMNSCSEDKYVTSAYQWMVPFLHRCEKQSPGVANELLKEYLVT 960

Query: 961  LAKGDLKFPLKIFQHSKPDLQQKIIPDQDQLMAIALECIYTCERNDQLCLCYDLLECLPE 1020
            LAKGDLKFPLKIFQHSKPDLQQKIIPDQDQLMAIALECIYTCERNDQLCLCYDLLECLPE
Sbjct: 961  LAKGDLKFPLKIFQHSKPDLQQKIIPDQDQLMAIALECIYTCERNDQLCLCYDLLECLPE 1020

Query: 1021 RGYGDKTEATTKLHDMVDQLEQILSVSELLEKHGLEKPISFVKNTQSSSEEARKLMVRLT 1080
            RGYGDKTEATTKLHDMVDQLEQILSVSELLEKHGLEKPISFVKNTQSSSEEARKLMVRLT
Sbjct: 1021 RGYGDKTEATTKLHDMVDQLEQILSVSELLEKHGLEKPISFVKNTQSSSEEARKLMVRLT 1080

Query: 1081 RHTGRKQPPVSESHWRTLLQDMLTMQQNVYTCLDSDACYEIFTESLLCSSRLENIHLAGQ 1140
            RHTGRKQPPVSESHWRTLLQDMLTMQQNVYTCLDSDACYEIFTESLLCSSRLENIHLAGQ
Sbjct: 1081 RHTGRKQPPVSESHWRTLLQDMLTMQQNVYTCLDSDACYEIFTESLLCSSRLENIHLAGQ 1140

Query: 1141 MMHCSACSENPPAGIAHKGKPHYRVSYEKSIDLVLAASREYFNSSTNLTDSCMDLARCCL 1200
            MMHCSACSENPPAGIAHKGKPHYRVSYEKSIDLVLAASREYFNSSTNLTDSCMDLARCCL
Sbjct: 1141 MMHCSACSENPPAGIAHKGKPHYRVSYEKSIDLVLAASREYFNSSTNLTDSCMDLARCCL 1200

Query: 1201 QLITDRPPAIQEELDLIQAVGCLEEFGVKILPLQVRLCPDRISLIKECISQSPTCYKQST 1260
            QLITDRPPAIQEELDLIQAVGCLEEFGVKILPLQVRLCPDRISLIKECISQSPTCYKQST
Sbjct: 1201 QLITDRPPAIQEELDLIQAVGCLEEFGVKILPLQVRLCPDRISLIKECISQSPTCYKQST 1260

Query: 1261 KLLGLAELLRVAGENPEERRGQVLILLVEQALRFHDYKAASMHCQELMATGYPKSWDVCS 1320
            KLLGLAELLRVAGENPEERRGQVLILLVEQALRFHDYKAASMHCQELMATGYPKSWDVCS
Sbjct: 1261 KLLGLAELLRVAGENPEERRGQVLILLVEQALRFHDYKAASMHCQELMATGYPKSWDVCS 1320

Query: 1321 QLGQSEGYQDLATRQELMAFALTHCPPSSIELLLAASSSLQTEILYQRVNFQIHHEGGEN 1380
            QLGQSEGYQDLATRQELMAFALTHCPPSSIELLLAASSSLQTEILYQRVNFQIHHEGGEN
Sbjct: 1321 QLGQSEGYQDLATRQELMAFALTHCPPSSIELLLAASSSLQTEILYQRVNFQIHHEGGEN 1380

Query: 1381 ISASPLTSKAVQEDEVGVPGSNSADLLRWTTATTMKVLSNTTTTTKAVLQAVSDGQWWKK 1440
            ISASPLTSKAVQEDEVGVPGSNSADLLRWTTATTMKVLSNTTTTTKAVLQAVSDGQWWKK
Sbjct: 1381 ISASPLTSKAVQEDEVGVPGSNSADLLRWTTATTMKVLSNTTTTTKAVLQAVSDGQWWKK 1440

Query: 1441 SLTYLRPLQGQKCGGAYQIGTTANEDLEKQGCHPFYESVISNPFVAESEGTYDTYQHVPV 1500
            SLTYLRPLQGQKCGGAYQIGTTANEDLEKQGCHPFYESVISNPFVAESEGTYDTYQHVPV
Sbjct: 1441 SLTYLRPLQGQKCGGAYQIGTTANEDLEKQGCHPFYESVISNPFVAESEGTYDTYQHVPV 1500

Query: 1501 ESFAEVLLRTGKLAEAKNKGEVFPTTEVLLQLASEALPNDMTLALAYLLALPQVLDANRC 1560
            ESFAEVLLRTGKLAEAKNKGEVFPTTEVLLQLASEALPNDMTLALAYLLALPQVLDANRC
Sbjct: 1501 ESFAEVLLRTGKLAEAKNKGEVFPTTEVLLQLASEALPNDMTLALAYLLALPQVLDANRC 1560

Query: 1561 FEKQSPSALSLQLAAYYYSLQIYARLAPCFRDKCHPLYRADPKELIKMVTRHVTRHEHEA 1620
            FEKQSPSALSLQLAAYYYSLQIYARLAPCFRDKCHPLYRADPKELIKMVTRHVTRHEHEA
Sbjct: 1561 FEKQSPSALSLQLAAYYYSLQIYARLAPCFRDKCHPLYRADPKELIKMVTRHVTRHEHEA 1620

Query: 1621 WPEDLISLTKQLHCYNERLLDFTQAQILQGLRKGVDVQRFTADDQYKRETILGLAETLEE 1680
            WPEDLISLTKQLHCYNERLLDFTQAQILQGLRKGVDVQRFTADDQYKRETILGLAETLEE
Sbjct: 1621 WPEDLISLTKQLHCYNERLLDFTQAQILQGLRKGVDVQRFTADDQYKRETILGLAETLEE 1680

Query: 1681 SVYSIAISLAQRYSVSRWEVFMTHLEFLFTDSGLSTLEIENRAQDLHLFETLKTDPEAFH 1740
            SVYSIAISLAQRYSVSRWEVFMTHLEFLFTDSGLSTLEIENRAQDLHLFETLKTDPEAFH
Sbjct: 1681 SVYSIAISLAQRYSVSRWEVFMTHLEFLFTDSGLSTLEIENRAQDLHLFETLKTDPEAFH 1740

Query: 1741 QHMVKYIYPTIGGFDHERLQYYFTLLENCGCADLGNCAIKPETHIRLLKKFKVVASGLNY 1800
            QHMVKYIYPTIGGFDHERLQYYFTLLENCGCADLGNCAIKPETHIRLLKKFKVVASGLNY
Sbjct: 1741 QHMVKYIYPTIGGFDHERLQYYFTLLENCGCADLGNCAIKPETHIRLLKKFKVVASGLNY 1800

Query: 1801 KKLTDENMSPLEALEPVLSSQNILSISKLVPKIPEKDGQMLSPSSLYTIWLQKLFWTGDP 1860
            KKLTDENMSPLEALEPVLSSQNILSISKLVPKIPEKDGQMLSPSSLYTIWLQKLFWTGDP
Sbjct: 1801 KKLTDENMSPLEALEPVLSSQNILSISKLVPKIPEKDGQMLSPSSLYTIWLQKLFWTGDP 1860

Query: 1861 HLIKQVPGSSPEWLHAYDVCMKYFDRLHPGDLITVVDAVTFSPKAVTKLSVEARKEMTRK 1920
            HLIKQVPGSSPEWLHAYDVCMKYFDRLHPGDLITVVDAVTFSPKAVTKLSVEARKEMTRK
Sbjct: 1861 HLIKQVPGSSPEWLHAYDVCMKYFDRLHPGDLITVVDAVTFSPKAVTKLSVEARKEMTRK 1920

Query: 1921 AIKTVKHFIEKPRKRNSEDEAQEAKDSKVTYADTLNHLEKSLAHLETLSHSFILSLKNSE 1980
            AIKTVKHFIEKPRKRNSEDEAQEAKDSKVTYADTLNHLEKSLAHLETLSHSFILSLKNSE
Sbjct: 1921 AIKTVKHFIEKPRKRNSEDEAQEAKDSKVTYADTLNHLEKSLAHLETLSHSFILSLKNSE 1980

Query: 1981 QETLQKYSHLYDLSRSEKEKLHDEAVAICLDGQPLAMIQQLLEVAVGPLDISPKDIVQSA 2040
            QETLQKYSHLYDLSRSEKEKLHDEAVAICLDGQPLAMIQQLLEVAVGPLDISPKDIVQSA
Sbjct: 1981 QETLQKYSHLYDLSRSEKEKLHDEAVAICLDGQPLAMIQQLLEVAVGPLDISPKDIVQSA 2040

Query: 2041 IMKIISALSGGSADLGGPRDPLKVLEGVVAAVHASVDKGEELVSPEDLLEWLRPFCADDA 2100
            IMKIISALSGGSADLGGPRDPLKVLEGVVAAVHASVDKGEELVSPEDLLEWLRPFCADDA
Sbjct: 2041 IMKIISALSGGSADLGGPRDPLKVLEGVVAAVHASVDKGEELVSPEDLLEWLRPFCADDA 2100

Query: 2101 WPVRPRIHVLQILGQSFHLTEEDSKLLVFFRTEAILKASWPQRQVDIADIENEENRYCLF 2160
            WPVRPRIHVLQILGQSFHLTEEDSKLLVFFRTEAILKASWPQRQVDIADIENEENRYCLF
Sbjct: 2101 WPVRPRIHVLQILGQSFHLTEEDSKLLVFFRTEAILKASWPQRQVDIADIENEENRYCLF 2160

Query: 2161 MELLESSHHEAEFQHLVLLLQAWPPMKSEYVITNNPWVRLATVMLTRCTMENKEGLGNEV 2220
            MELLESSHHEAEFQHLVLLLQAWPPMKSEYVITNNPWVRLATVMLTRCTMENKEGLGNEV
Sbjct: 2161 MELLESSHHEAEFQHLVLLLQAWPPMKSEYVITNNPWVRLATVMLTRCTMENKEGLGNEV 2220

Query: 2221 LKMCRSLYNTKQMLPAEGVKELCLLLLNQSLLLPSLKLLLESRDEHLHEMALEQITAVTT 2280
            LKMCRSLYNTKQMLPAEGVKELCLLLLNQSLLLPSLKLLLESRDEHLHEMALEQITAVTT
Sbjct: 2221 LKMCRSLYNTKQMLPAEGVKELCLLLLNQSLLLPSLKLLLESRDEHLHEMALEQITAVTT 2280

Query: 2281 VNDSNCDQELLSLLLDAKLLVKCVSTPFYPRIVDHLLASLQQGRWDAEELGRHLREAGHE 2340
            VNDSNCDQELLSLLLDAKLLVKCVSTPFYPRIVDHLLASLQQGRWDAEELGRHLREAGHE
Sbjct: 2281 VNDSNCDQELLSLLLDAKLLVKCVSTPFYPRIVDHLLASLQQGRWDAEELGRHLREAGHE 2340

Query: 2341 AEAGSLLLAVRGTHQAFRTFSTALRAAQHWV 2371
            AEAGSLLLAVRGTHQAFRTFSTALRAAQHWV
Sbjct: 2341 AEAGSLLLAVRGTHQAFRTFSTALRAAQHWV 2371


>gi|50658069 phosphodiesterase 4D interacting protein isoform 2 [Homo
            sapiens]
          Length = 969

 Score = 37.4 bits (85), Expect = 0.18
 Identities = 28/118 (23%), Positives = 61/118 (51%), Gaps = 7/118 (5%)

Query: 1893 ITVVDAVTFSPKAVTKLSVEARKEMTRKAIKTVKHFIEKPRKRNSEDEAQEAKDSKVTYA 1952
            +  V+A     +   + S +  +E+ RKA++ ++  ++   ++    EA++  + + T  
Sbjct: 376  VQFVEAAAHESEQQKEASWKHNQEL-RKALQQLQEELQNKSQQLRAWEAEKYNEIR-TQE 433

Query: 1953 DTLNHLEKSLAHLETLSHSF--ILSLKNSEQETLQKYSHLYDLSRSEKEKLHDEAVAI 2008
              + HL  SL+H E L   F  +L  +++  +TL+    L +  R   +++HD+AVA+
Sbjct: 434  QNIQHLNHSLSHKEQLLQEFRELLQYRDNSDKTLEANEMLLEKLR---QRIHDKAVAL 488



 Score = 33.9 bits (76), Expect = 2.0
 Identities = 21/72 (29%), Positives = 37/72 (51%), Gaps = 1/72 (1%)

Query: 1934 KRNSEDEAQEAKDSKVTYADTLNHLEKSLAHLETLSHSFILSLKNSEQETLQKYSHLYDL 1993
            KRN E +  E +  K    D   HL+K+ A +E L+      L+   +E  Q+  H+Y+L
Sbjct: 46   KRNIELKV-EVESLKRELQDKKQHLDKTWADVENLNSQNEAELRRQFEERQQETEHVYEL 104

Query: 1994 SRSEKEKLHDEA 2005
              ++ + L +E+
Sbjct: 105  LENKIQLLQEES 116


>gi|50658071 phosphodiesterase 4D interacting protein isoform 5 [Homo
            sapiens]
          Length = 1132

 Score = 37.4 bits (85), Expect = 0.18
 Identities = 28/118 (23%), Positives = 61/118 (51%), Gaps = 7/118 (5%)

Query: 1893 ITVVDAVTFSPKAVTKLSVEARKEMTRKAIKTVKHFIEKPRKRNSEDEAQEAKDSKVTYA 1952
            +  V+A     +   + S +  +E+ RKA++ ++  ++   ++    EA++  + + T  
Sbjct: 539  VQFVEAAAHESEQQKEASWKHNQEL-RKALQQLQEELQNKSQQLRAWEAEKYNEIR-TQE 596

Query: 1953 DTLNHLEKSLAHLETLSHSF--ILSLKNSEQETLQKYSHLYDLSRSEKEKLHDEAVAI 2008
              + HL  SL+H E L   F  +L  +++  +TL+    L +  R   +++HD+AVA+
Sbjct: 597  QNIQHLNHSLSHKEQLLQEFRELLQYRDNSDKTLEANEMLLEKLR---QRIHDKAVAL 651


>gi|157311604 phosphodiesterase 4D interacting protein isoform 1 [Homo
            sapiens]
          Length = 2346

 Score = 37.4 bits (85), Expect = 0.18
 Identities = 28/118 (23%), Positives = 61/118 (51%), Gaps = 7/118 (5%)

Query: 1893 ITVVDAVTFSPKAVTKLSVEARKEMTRKAIKTVKHFIEKPRKRNSEDEAQEAKDSKVTYA 1952
            +  V+A     +   + S +  +E+ RKA++ ++  ++   ++    EA++  + + T  
Sbjct: 376  VQFVEAAAHESEQQKEASWKHNQEL-RKALQQLQEELQNKSQQLRAWEAEKYNEIR-TQE 433

Query: 1953 DTLNHLEKSLAHLETLSHSF--ILSLKNSEQETLQKYSHLYDLSRSEKEKLHDEAVAI 2008
              + HL  SL+H E L   F  +L  +++  +TL+    L +  R   +++HD+AVA+
Sbjct: 434  QNIQHLNHSLSHKEQLLQEFRELLQYRDNSDKTLEANEMLLEKLR---QRIHDKAVAL 488



 Score = 33.9 bits (76), Expect = 2.0
 Identities = 21/72 (29%), Positives = 37/72 (51%), Gaps = 1/72 (1%)

Query: 1934 KRNSEDEAQEAKDSKVTYADTLNHLEKSLAHLETLSHSFILSLKNSEQETLQKYSHLYDL 1993
            KRN E +  E +  K    D   HL+K+ A +E L+      L+   +E  Q+  H+Y+L
Sbjct: 46   KRNIELKV-EVESLKRELQDKKQHLDKTWADVENLNSQNEAELRRQFEERQQETEHVYEL 104

Query: 1994 SRSEKEKLHDEA 2005
              ++ + L +E+
Sbjct: 105  LENKIQLLQEES 116


>gi|4503179 oral-facial-digital syndrome 1 [Homo sapiens]
          Length = 1012

 Score = 36.2 bits (82), Expect = 0.39
 Identities = 43/194 (22%), Positives = 83/194 (42%), Gaps = 43/194 (22%)

Query: 507 KRPRTITKNYRLVSLRSTTPEELYQRKIESEEYEEALSLAHTYGLDTDLVYQRQWRKSAV 566
           ++ ++IT+  R       + EE Y RK+++E  +  L L   Y + T+ + + + RK+  
Sbjct: 319 EKHKSITEALRRQEQNIKSFEETYDRKLKNELLKYQLELKDDYIIRTNRLIEDE-RKNKE 377

Query: 567 NVASIQNYLSKIKKRSWVLHECLERVPENVDAAKELLQYGLKGTDLEALLAIGKGADDGR 626
               +Q  L  I  +        E + ++V+  KEL                        
Sbjct: 378 KAVHLQEELIAINSKK-------EELNQSVNRVKEL------------------------ 406

Query: 627 FTLPGEIDIDSISYEELSPPDEEPAKNKKEKELKK----RQELLKLVNFSKLTLEQKELC 682
                E++++S+  + L+   +    N+K KE+      ++E L+L+  +KL  +Q E  
Sbjct: 407 -----ELELESVKAQSLAITKQNHMLNEKVKEMSDYSLLKEEKLELLAQNKLLKQQLE-- 459

Query: 683 RCRRKLLTYLDRLA 696
             R + L  L+RLA
Sbjct: 460 ESRNENLRLLNRLA 473


>gi|56550047 uveal autoantigen with coiled-coil domains and ankyrin
            repeats isoform 2 [Homo sapiens]
          Length = 1403

 Score = 35.8 bits (81), Expect = 0.51
 Identities = 37/151 (24%), Positives = 67/151 (44%), Gaps = 16/151 (10%)

Query: 1904 KAVTKLSVEAR-KEMTRKAIKTVKHFIEKPRKRNSEDEAQEAKDSKVT-YADTLNHLEKS 1961
            K +   S+E   K+   +  K++    E  R+     +  EAKD+K+T   + +  L+++
Sbjct: 1262 KELLHFSIEQEIKDQKERCDKSLTTITELQRRIQESAKQIEAKDNKITELLNDVERLKQA 1321

Query: 1962 LAHLETLSHSFILSLKNSEQ--ETLQKYSHLYDLSRSEKEKLHDEAVAICLDGQPLAMIQ 2019
            L  L  L+++     K   Q  +TLQ      +   ++ ++ H E +AI           
Sbjct: 1322 LNGLSQLTYTSGNPTKRQSQLIDTLQHQVKSLEQQLADADRQHQEVIAI--------YRT 1373

Query: 2020 QLLEVAVGPLDISPKDIVQSAIMKIISALSG 2050
             LL  A G +D    + VQ A+++II    G
Sbjct: 1374 HLLSAAQGHMD----EDVQEALLQIIQMRQG 1400


>gi|59850762 uveal autoantigen with coiled-coil domains and ankyrin
            repeats isoform 1 [Homo sapiens]
          Length = 1416

 Score = 35.8 bits (81), Expect = 0.51
 Identities = 37/151 (24%), Positives = 67/151 (44%), Gaps = 16/151 (10%)

Query: 1904 KAVTKLSVEAR-KEMTRKAIKTVKHFIEKPRKRNSEDEAQEAKDSKVT-YADTLNHLEKS 1961
            K +   S+E   K+   +  K++    E  R+     +  EAKD+K+T   + +  L+++
Sbjct: 1275 KELLHFSIEQEIKDQKERCDKSLTTITELQRRIQESAKQIEAKDNKITELLNDVERLKQA 1334

Query: 1962 LAHLETLSHSFILSLKNSEQ--ETLQKYSHLYDLSRSEKEKLHDEAVAICLDGQPLAMIQ 2019
            L  L  L+++     K   Q  +TLQ      +   ++ ++ H E +AI           
Sbjct: 1335 LNGLSQLTYTSGNPTKRQSQLIDTLQHQVKSLEQQLADADRQHQEVIAI--------YRT 1386

Query: 2020 QLLEVAVGPLDISPKDIVQSAIMKIISALSG 2050
             LL  A G +D    + VQ A+++II    G
Sbjct: 1387 HLLSAAQGHMD----EDVQEALLQIIQMRQG 1413


>gi|7661960 Rough Deal homolog, centromere/kinetochore protein [Homo
           sapiens]
          Length = 2209

 Score = 35.0 bits (79), Expect = 0.88
 Identities = 31/120 (25%), Positives = 48/120 (40%), Gaps = 27/120 (22%)

Query: 521 LRSTTPEELYQRKIESEEYEEALSLAHTYGLDTDLVY--------------------QRQ 560
           L    PE    R +    + EA S A  +GLD +LVY                    Q +
Sbjct: 391 LTEALPENRLSRLLHKHRFAEAESFAIQFGLDVELVYKVKSNHILEKLALSSVDASEQTE 450

Query: 561 WRKSAVNVASIQNYLSKIKKRSWVLHECLERVPENVDAAKELLQYG----LKGTDLEALL 616
           W++    V   +  L KI+   +V++ CL+      +  +E+L Y     LK  D  AL+
Sbjct: 451 WQQL---VDDAKENLHKIQDDEFVVNYCLKAQWITYETTQEMLNYAKTRLLKKEDKTALI 507


>gi|186928844 Cdc42 GTPase-activating protein [Homo sapiens]
          Length = 1444

 Score = 34.7 bits (78), Expect = 1.1
 Identities = 34/129 (26%), Positives = 56/129 (43%), Gaps = 14/129 (10%)

Query: 314 QGQEQDGIFKMSLSPDGMLLAA--IHFSGKLSIWAIPSLKQQGEWGQNEQP-----GYDD 366
           +G+E  G F  +++  G  + A  +H +G  S  +    KQ+GEWGQ   P     G+D 
Sbjct: 356 EGKETKGNFNRTVTTGGFFIPATKMHSTGTGS--SCDLTKQEGEWGQEGMPPGAEGGFDV 413

Query: 367 LNPDWRL-STEKRKKIKDKESFYPLIDVNWWADSAVTLARCSGALTVSSVKTLKNLLGKS 425
            +    L   + R   +  + F P+ D     +S  T  +  G    S+    K++   S
Sbjct: 414 SSDRSHLQGAQARPPPEQLKVFRPVED----PESEQTAPKMLGMFYTSNDSPSKSVFTSS 469

Query: 426 CEWFEPSPQ 434
               EPSP+
Sbjct: 470 LFQMEPSPR 478


>gi|55956890 kelch/ankyrin repeat containing cyclin A1 interacting
           protein isoform b [Homo sapiens]
          Length = 288

 Score = 34.7 bits (78), Expect = 1.1
 Identities = 17/34 (50%), Positives = 19/34 (55%)

Query: 227 HCFSFSSHYPHGINTAIYHPGHRLLLVGGCETAE 260
           H  S S H    + T   HPGH+LLL GGC  AE
Sbjct: 183 HTASRSGHCAALLQTPGPHPGHQLLLFGGCNLAE 216


>gi|55956888 kelch/ankyrin repeat containing cyclin A1 interacting
           protein isoform a [Homo sapiens]
          Length = 349

 Score = 34.7 bits (78), Expect = 1.1
 Identities = 17/34 (50%), Positives = 19/34 (55%)

Query: 227 HCFSFSSHYPHGINTAIYHPGHRLLLVGGCETAE 260
           H  S S H    + T   HPGH+LLL GGC  AE
Sbjct: 183 HTASRSGHCAALLQTPGPHPGHQLLLFGGCNLAE 216


>gi|169217489 PREDICTED: similar to phosphodiesterase 4D interacting
            protein [Homo sapiens]
          Length = 211

 Score = 34.3 bits (77), Expect = 1.5
 Identities = 24/95 (25%), Positives = 50/95 (52%), Gaps = 6/95 (6%)

Query: 1916 EMTRKAIKTVKHFIEKPRKRNSEDEAQEAKDSKVTYADTLNHLEKSLAHLETLSHSF--I 1973
            E  RKA++ ++  ++   ++    EA++  + + T    + HL  SL+H E L   F  +
Sbjct: 2    EELRKALQQLQEELQNKSQQLRAWEAEKYNEIR-TQEQNIQHLNHSLSHKEQLLQEFREL 60

Query: 1974 LSLKNSEQETLQKYSHLYDLSRSEKEKLHDEAVAI 2008
            L  +++  +TL+    L +  R   +++ D+AVA+
Sbjct: 61   LQYRDNSDKTLEANEMLLEKLR---QRIRDKAVAL 92


>gi|50658077 phosphodiesterase 4D interacting protein isoform 4 [Homo
            sapiens]
          Length = 173

 Score = 33.9 bits (76), Expect = 2.0
 Identities = 21/72 (29%), Positives = 37/72 (51%), Gaps = 1/72 (1%)

Query: 1934 KRNSEDEAQEAKDSKVTYADTLNHLEKSLAHLETLSHSFILSLKNSEQETLQKYSHLYDL 1993
            KRN E +  E +  K    D   HL+K+ A +E L+      L+   +E  Q+  H+Y+L
Sbjct: 46   KRNIELKV-EVESLKRELQDKKQHLDKTWADVENLNSQNEAELRRQFEERQQETEHVYEL 104

Query: 1994 SRSEKEKLHDEA 2005
              ++ + L +E+
Sbjct: 105  LENKIQLLQEES 116


>gi|50658075 phosphodiesterase 4D interacting protein isoform 3 [Homo
            sapiens]
          Length = 310

 Score = 33.9 bits (76), Expect = 2.0
 Identities = 21/72 (29%), Positives = 37/72 (51%), Gaps = 1/72 (1%)

Query: 1934 KRNSEDEAQEAKDSKVTYADTLNHLEKSLAHLETLSHSFILSLKNSEQETLQKYSHLYDL 1993
            KRN E +  E +  K    D   HL+K+ A +E L+      L+   +E  Q+  H+Y+L
Sbjct: 183  KRNIELKV-EVESLKRELQDKKQHLDKTWADVENLNSQNEAELRRQFEERQQETEHVYEL 241

Query: 1994 SRSEKEKLHDEA 2005
              ++ + L +E+
Sbjct: 242  LENKIQLLQEES 253


>gi|195976782 Paf1/RNA polymerase II complex component [Homo sapiens]
          Length = 710

 Score = 33.9 bits (76), Expect = 2.0
 Identities = 23/110 (20%), Positives = 48/110 (43%), Gaps = 15/110 (13%)

Query: 1906 VTKLSVEARKEMTRKAIKTVKHFIEKPRKRNSEDEAQEAKDSKVTYADTLNHLEKSLAHL 1965
            + K  V  R+   +K +KT K   +K +K+  E+E ++ K +++  +   +H ++     
Sbjct: 212  IEKREVLKRRFEIKKKLKTAKKKEKKEKKKKQEEEQEKKKLTQIQESQVTSHNKER---- 267

Query: 1966 ETLSHSFILSLKNSEQETLQKYSHLYDLSRSEKEKLHDEAVAICLDGQPL 2015
                       ++   E L K S   +  ++E+EK  +    +    QPL
Sbjct: 268  -----------RSKRDEKLDKKSQAMEELKAEREKRKNRTAELLAKKQPL 306


>gi|34222391 zinc finger protein 605 [Homo sapiens]
          Length = 641

 Score = 33.9 bits (76), Expect = 2.0
 Identities = 33/124 (26%), Positives = 50/124 (40%), Gaps = 12/124 (9%)

Query: 1053 HGLEKPISFVKNTQSSSEEARKLMVRLTRHTGRKQPPVSESHWRTLLQDMLTMQQNVYT- 1111
            H +EKP S  +  ++ S++  KL+     HTG K  P S        +  L   Q  +T 
Sbjct: 275  HTIEKPYSCSECGKAFSQKL-KLITHQRAHTGEKPYPCSHCGKAFFWKSQLITHQRTHTG 333

Query: 1112 --CLDSDACYEIFTESLLCSSRLENIHLAGQMMHCSACSE---NPPA----GIAHKGKPH 1162
                    C + F+ + L   R + IH   +   C+ C E     P      I H G+ +
Sbjct: 334  KKPYGCGECQKAFSRNSLL-IRHQRIHTGEKPYECNECGEAFIRKPQLIKHQITHTGEKN 392

Query: 1163 YRVS 1166
            YR S
Sbjct: 393  YRCS 396


>gi|223005859 WD repeat domain 67 isoform 1 [Homo sapiens]
          Length = 1066

 Score = 33.5 bits (75), Expect = 2.6
 Identities = 17/62 (27%), Positives = 33/62 (53%)

Query: 292 GVTAVPKTLGLLRMLSVKFYSRQGQEQDGIFKMSLSPDGMLLAAIHFSGKLSIWAIPSLK 351
           GV +    +  + M + K     G   +GI   ++SP G  +A+I  +G L+I+++ +L 
Sbjct: 280 GVLSQDGIMRFINMQTCKLLFEIGSLDEGISSSAISPHGRYIASIMENGSLNIYSVQALT 339

Query: 352 QQ 353
           Q+
Sbjct: 340 QE 341


>gi|223005857 WD repeat domain 67 isoform 2 [Homo sapiens]
          Length = 970

 Score = 33.5 bits (75), Expect = 2.6
 Identities = 17/62 (27%), Positives = 33/62 (53%)

Query: 292 GVTAVPKTLGLLRMLSVKFYSRQGQEQDGIFKMSLSPDGMLLAAIHFSGKLSIWAIPSLK 351
           GV +    +  + M + K     G   +GI   ++SP G  +A+I  +G L+I+++ +L 
Sbjct: 280 GVLSQDGIMRFINMQTCKLLFEIGSLDEGISSSAISPHGRYIASIMENGSLNIYSVQALT 339

Query: 352 QQ 353
           Q+
Sbjct: 340 QE 341


>gi|94538370 DnaJ (Hsp40) homolog, subfamily C, member 2 isoform 1
            [Homo sapiens]
          Length = 621

 Score = 33.5 bits (75), Expect = 2.6
 Identities = 46/246 (18%), Positives = 97/246 (39%), Gaps = 14/246 (5%)

Query: 1812 EALEPVLSSQNILSISKLVPKIPEKDGQMLSPSSLYTIWLQKLFWTGDPHLIKQVPGSSP 1871
            E   PV    +  S  K VPK+ + +         Y+ W     W    +L ++    + 
Sbjct: 180  EVFTPVFERNSRWSNKKNVPKLGDMNSSFEDVDIFYSFWYNFDSWREFSYLDEEEKEKAE 239

Query: 1872 -----EWLHAYDVCMKYFDRLHPGDLI-TVVDAVTFSPKAVTKLSVE--ARKEMTRKAIK 1923
                  W+   +   +   +    + I T+VD        + K   E  A+KE  +KA  
Sbjct: 240  CRDERRWIEKQNRATRAQRKKEEMNRIRTLVDNAYSCDPRIKKFKEEEKAKKEAEKKAKA 299

Query: 1924 TVKHFIEKPRKRNSEDEAQEAKDSKVTYADTLNHLEKSLAHLETLSHSFILSLKNSEQET 1983
              K   ++ +++  + E + A+ +K    + +          + +    I   +   + +
Sbjct: 300  EAKRKEQEAKEKQRQAELEAARLAKEKEEEEVRQQALLAKKEKDIQKKAIKKERQKLRNS 359

Query: 1984 LQKYSHLYDLSRSEKEKLHDEAVAICLDGQPLAMIQQLLEVAVGPLDISPKDIVQSAIMK 2043
             + ++H  D + +E+ K+ +E   +C D   LA +Q L E     L    K++ ++A+ K
Sbjct: 360  CKTWNHFSD-NEAERVKMMEEVEKLC-DRLELASLQCLNET----LTSCTKEVGKAALEK 413

Query: 2044 IISALS 2049
             I  ++
Sbjct: 414  QIEEIN 419


>gi|7662386 NLR family, pyrin domain containing 1 isoform 2 [Homo
            sapiens]
          Length = 1429

 Score = 32.7 bits (73), Expect = 4.4
 Identities = 38/164 (23%), Positives = 73/164 (44%), Gaps = 30/164 (18%)

Query: 2155 NRYCLFMELLESSHHEAEFQHLVLLLQAWPPMKSEYVITNNPWVRLATVMLTRCTMENKE 2214
            +R+   ++L+E   H + +   +++L  W P+   Y      W  L +V+     ++  +
Sbjct: 761  SRHVKKLQLIEGRQHRSTWSPTMVVLFRWVPVTDAY------WQILFSVLKVTRNLKELD 814

Query: 2215 GLGNE-----VLKMCRSLYNTKQM----------LPAEGVKELCL-LLLNQSL--LLPSL 2256
              GN      V  +C++L   + +          L AE  K+L   L  NQ+L  L  S 
Sbjct: 815  LSGNSLSHSAVKSLCKTLRRPRCLLETLRLAGCGLTAEDCKDLAFGLRANQTLTELDLSF 874

Query: 2257 KLLLESRDEHLHE------MALEQITAVTTVNDSNCDQELLSLL 2294
             +L ++  +HL +        L+++  V+    S+C Q+L S+L
Sbjct: 875  NVLTDAGAKHLCQRLRQPSCKLQRLQLVSCGLTSDCCQDLASVL 918


>gi|14719835 NLR family, pyrin domain containing 1 isoform 4 [Homo
            sapiens]
          Length = 1399

 Score = 32.7 bits (73), Expect = 4.4
 Identities = 38/164 (23%), Positives = 73/164 (44%), Gaps = 30/164 (18%)

Query: 2155 NRYCLFMELLESSHHEAEFQHLVLLLQAWPPMKSEYVITNNPWVRLATVMLTRCTMENKE 2214
            +R+   ++L+E   H + +   +++L  W P+   Y      W  L +V+     ++  +
Sbjct: 761  SRHVKKLQLIEGRQHRSTWSPTMVVLFRWVPVTDAY------WQILFSVLKVTRNLKELD 814

Query: 2215 GLGNE-----VLKMCRSLYNTKQM----------LPAEGVKELCL-LLLNQSL--LLPSL 2256
              GN      V  +C++L   + +          L AE  K+L   L  NQ+L  L  S 
Sbjct: 815  LSGNSLSHSAVKSLCKTLRRPRCLLETLRLAGCGLTAEDCKDLAFGLRANQTLTELDLSF 874

Query: 2257 KLLLESRDEHLHE------MALEQITAVTTVNDSNCDQELLSLL 2294
             +L ++  +HL +        L+++  V+    S+C Q+L S+L
Sbjct: 875  NVLTDAGAKHLCQRLRQPSCKLQRLQLVSCGLTSDCCQDLASVL 918


>gi|74271814 NLR family, pyrin domain containing 1 isoform 5 [Homo
            sapiens]
          Length = 1375

 Score = 32.7 bits (73), Expect = 4.4
 Identities = 38/164 (23%), Positives = 73/164 (44%), Gaps = 30/164 (18%)

Query: 2155 NRYCLFMELLESSHHEAEFQHLVLLLQAWPPMKSEYVITNNPWVRLATVMLTRCTMENKE 2214
            +R+   ++L+E   H + +   +++L  W P+   Y      W  L +V+     ++  +
Sbjct: 761  SRHVKKLQLIEGRQHRSTWSPTMVVLFRWVPVTDAY------WQILFSVLKVTRNLKELD 814

Query: 2215 GLGNE-----VLKMCRSLYNTKQM----------LPAEGVKELCL-LLLNQSL--LLPSL 2256
              GN      V  +C++L   + +          L AE  K+L   L  NQ+L  L  S 
Sbjct: 815  LSGNSLSHSAVKSLCKTLRRPRCLLETLRLAGCGLTAEDCKDLAFGLRANQTLTELDLSF 874

Query: 2257 KLLLESRDEHLHE------MALEQITAVTTVNDSNCDQELLSLL 2294
             +L ++  +HL +        L+++  V+    S+C Q+L S+L
Sbjct: 875  NVLTDAGAKHLCQRLRQPSCKLQRLQLVSCGLTSDCCQDLASVL 918


>gi|14719833 NLR family, pyrin domain containing 1 isoform 3 [Homo
            sapiens]
          Length = 1443

 Score = 32.7 bits (73), Expect = 4.4
 Identities = 38/164 (23%), Positives = 73/164 (44%), Gaps = 30/164 (18%)

Query: 2155 NRYCLFMELLESSHHEAEFQHLVLLLQAWPPMKSEYVITNNPWVRLATVMLTRCTMENKE 2214
            +R+   ++L+E   H + +   +++L  W P+   Y      W  L +V+     ++  +
Sbjct: 761  SRHVKKLQLIEGRQHRSTWSPTMVVLFRWVPVTDAY------WQILFSVLKVTRNLKELD 814

Query: 2215 GLGNE-----VLKMCRSLYNTKQM----------LPAEGVKELCL-LLLNQSL--LLPSL 2256
              GN      V  +C++L   + +          L AE  K+L   L  NQ+L  L  S 
Sbjct: 815  LSGNSLSHSAVKSLCKTLRRPRCLLETLRLAGCGLTAEDCKDLAFGLRANQTLTELDLSF 874

Query: 2257 KLLLESRDEHLHE------MALEQITAVTTVNDSNCDQELLSLL 2294
             +L ++  +HL +        L+++  V+    S+C Q+L S+L
Sbjct: 875  NVLTDAGAKHLCQRLRQPSCKLQRLQLVSCGLTSDCCQDLASVL 918


>gi|14719829 NLR family, pyrin domain containing 1 isoform 1 [Homo
            sapiens]
          Length = 1473

 Score = 32.7 bits (73), Expect = 4.4
 Identities = 38/164 (23%), Positives = 73/164 (44%), Gaps = 30/164 (18%)

Query: 2155 NRYCLFMELLESSHHEAEFQHLVLLLQAWPPMKSEYVITNNPWVRLATVMLTRCTMENKE 2214
            +R+   ++L+E   H + +   +++L  W P+   Y      W  L +V+     ++  +
Sbjct: 761  SRHVKKLQLIEGRQHRSTWSPTMVVLFRWVPVTDAY------WQILFSVLKVTRNLKELD 814

Query: 2215 GLGNE-----VLKMCRSLYNTKQM----------LPAEGVKELCL-LLLNQSL--LLPSL 2256
              GN      V  +C++L   + +          L AE  K+L   L  NQ+L  L  S 
Sbjct: 815  LSGNSLSHSAVKSLCKTLRRPRCLLETLRLAGCGLTAEDCKDLAFGLRANQTLTELDLSF 874

Query: 2257 KLLLESRDEHLHE------MALEQITAVTTVNDSNCDQELLSLL 2294
             +L ++  +HL +        L+++  V+    S+C Q+L S+L
Sbjct: 875  NVLTDAGAKHLCQRLRQPSCKLQRLQLVSCGLTSDCCQDLASVL 918


>gi|155030226 phosphatidylinositol 4-kinase type 3 alpha isoform 2
            [Homo sapiens]
          Length = 2044

 Score = 32.7 bits (73), Expect = 4.4
 Identities = 61/239 (25%), Positives = 89/239 (37%), Gaps = 53/239 (22%)

Query: 1826 ISKLVPKIPE-----------------KDGQMLSPSSLYTIWLQKLFW--TGDPHLIKQV 1866
            +SKL PKIP                   D + + PS+L T+  +      T     I QV
Sbjct: 147  LSKLFPKIPPHSLRVLEELEGVRRRSFNDFRSILPSNLLTVCQEGTLKRKTSSVSSISQV 206

Query: 1867 -------PGSSP--EWLHAYDV-CMKYFDRLHPGDLI-TVVDAVTFSP--KAVTKLSVEA 1913
                   P SSP     H ++  C+     L P     T+  + + SP    VT      
Sbjct: 207  SPERGMPPPSSPGGSAFHYFEASCLPDGTALEPEYYFSTISSSFSVSPLFNGVTYKEFNI 266

Query: 1914 RKEMTRKAIKTVKHFIEKPRKRN------SEDEAQEAKDSKVT------YADTLNHLEKS 1961
              EM R+ +  VK  +E+   ++      S  EA  + D   T      Y      L  +
Sbjct: 267  PLEMLRELLNLVKKIVEEAVLKSLDAIVASVMEANPSADLYYTSFSDPLYLTMFKMLRDT 326

Query: 1962 LAHLETLS-------HSFILSLKNSEQETLQKYSHLYDLSRSEKE--KLHDEAVAICLD 2011
            L +++ L        H F+L   N+ Q  LQK  H  D   +E    KL  +A A C+D
Sbjct: 327  LYYMKDLPTSFVKEIHDFVLEQFNTSQGELQKILHDADRIHNELSPLKLRCQANAACVD 385


>gi|199559532 Abelson helper integration site 1 isoform b [Homo
           sapiens]
          Length = 1053

 Score = 32.7 bits (73), Expect = 4.4
 Identities = 29/118 (24%), Positives = 58/118 (49%), Gaps = 10/118 (8%)

Query: 365 DDLNPDWRLSTEKRKKIKDKESFYPLIDVNWWADSAVTLARCSGALTVSSVKTLKNLLGK 424
           D L  D +LS+EKRKK K+   F           S +T++  +         +++++   
Sbjct: 222 DTLFHDDKLSSEKRKKKKEVPVFSKA------ETSTLTISGDTVEGEQKKESSVRSVSSD 275

Query: 425 SCEWFEPSPQVTATHDGGFLSLECEIKLAPKRSRLETRAGEEDEGEEDSDSDYEISAK 482
           S +  E S    +T D    S++ + K  PK+++ +T+A  ++  + D D  +EI+++
Sbjct: 276 SHQDDEISSMEQSTED----SMQDDTKPKPKKTKKKTKAVADNNEDVDGDGVHEITSR 329


>gi|199559490 Abelson helper integration site 1 isoform a [Homo
           sapiens]
          Length = 1196

 Score = 32.7 bits (73), Expect = 4.4
 Identities = 29/118 (24%), Positives = 58/118 (49%), Gaps = 10/118 (8%)

Query: 365 DDLNPDWRLSTEKRKKIKDKESFYPLIDVNWWADSAVTLARCSGALTVSSVKTLKNLLGK 424
           D L  D +LS+EKRKK K+   F           S +T++  +         +++++   
Sbjct: 222 DTLFHDDKLSSEKRKKKKEVPVFSKA------ETSTLTISGDTVEGEQKKESSVRSVSSD 275

Query: 425 SCEWFEPSPQVTATHDGGFLSLECEIKLAPKRSRLETRAGEEDEGEEDSDSDYEISAK 482
           S +  E S    +T D    S++ + K  PK+++ +T+A  ++  + D D  +EI+++
Sbjct: 276 SHQDDEISSMEQSTED----SMQDDTKPKPKKTKKKTKAVADNNEDVDGDGVHEITSR 329


>gi|199559438 Abelson helper integration site 1 isoform a [Homo
           sapiens]
          Length = 1196

 Score = 32.7 bits (73), Expect = 4.4
 Identities = 29/118 (24%), Positives = 58/118 (49%), Gaps = 10/118 (8%)

Query: 365 DDLNPDWRLSTEKRKKIKDKESFYPLIDVNWWADSAVTLARCSGALTVSSVKTLKNLLGK 424
           D L  D +LS+EKRKK K+   F           S +T++  +         +++++   
Sbjct: 222 DTLFHDDKLSSEKRKKKKEVPVFSKA------ETSTLTISGDTVEGEQKKESSVRSVSSD 275

Query: 425 SCEWFEPSPQVTATHDGGFLSLECEIKLAPKRSRLETRAGEEDEGEEDSDSDYEISAK 482
           S +  E S    +T D    S++ + K  PK+++ +T+A  ++  + D D  +EI+++
Sbjct: 276 SHQDDEISSMEQSTED----SMQDDTKPKPKKTKKKTKAVADNNEDVDGDGVHEITSR 329


>gi|31542701 Abelson helper integration site 1 isoform a [Homo
           sapiens]
          Length = 1196

 Score = 32.7 bits (73), Expect = 4.4
 Identities = 29/118 (24%), Positives = 58/118 (49%), Gaps = 10/118 (8%)

Query: 365 DDLNPDWRLSTEKRKKIKDKESFYPLIDVNWWADSAVTLARCSGALTVSSVKTLKNLLGK 424
           D L  D +LS+EKRKK K+   F           S +T++  +         +++++   
Sbjct: 222 DTLFHDDKLSSEKRKKKKEVPVFSKA------ETSTLTISGDTVEGEQKKESSVRSVSSD 275

Query: 425 SCEWFEPSPQVTATHDGGFLSLECEIKLAPKRSRLETRAGEEDEGEEDSDSDYEISAK 482
           S +  E S    +T D    S++ + K  PK+++ +T+A  ++  + D D  +EI+++
Sbjct: 276 SHQDDEISSMEQSTED----SMQDDTKPKPKKTKKKTKAVADNNEDVDGDGVHEITSR 329


>gi|24308069 zinc finger protein 521 [Homo sapiens]
          Length = 1311

 Score = 32.7 bits (73), Expect = 4.4
 Identities = 24/91 (26%), Positives = 36/91 (39%), Gaps = 16/91 (17%)

Query: 1062 VKNTQSSS--EEARKLMVRLTRHTGRKQPPVSESHWRTLLQDMLTMQQNVYTCLDSDACY 1119
            +K+TQ  S  EE       L +H     P  S +  R  LQ +               C+
Sbjct: 242  MKDTQKCSQCEEGFDFPEDLQKHIAECHPECSPNEDRAALQCVY--------------CH 287

Query: 1120 EIFTESLLCSSRLENIHLAGQMMHCSACSEN 1150
            E+F E     + +E +H   +   CS CSE+
Sbjct: 288  ELFVEETSLMNHMEQVHSGEKKNSCSICSES 318


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.318    0.133    0.397 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 90,671,769
Number of Sequences: 37866
Number of extensions: 4130910
Number of successful extensions: 12566
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 10
Number of HSP's successfully gapped in prelim test: 34
Number of HSP's that attempted gapping in prelim test: 12478
Number of HSP's gapped (non-prelim): 136
length of query: 2371
length of database: 18,247,518
effective HSP length: 119
effective length of query: 2252
effective length of database: 13,741,464
effective search space: 30945776928
effective search space used: 30945776928
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 70 (31.6 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

CSHL Press