Guide to the Human Genome
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Search of human proteins with 41349464

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|41349464 PR domain containing 10 isoform 4 [Homo sapiens]
         (1023 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|41349464 PR domain containing 10 isoform 4 [Homo sapiens]         2114   0.0  
gi|41349462 PR domain containing 10 isoform 3 [Homo sapiens]         2091   0.0  
gi|41349460 PR domain containing 10 isoform 2 [Homo sapiens]         2072   0.0  
gi|41349458 PR domain containing 10 isoform 1 [Homo sapiens]         2066   0.0  
gi|94536868 PR domain containing 15 isoform 2 [Homo sapiens]          206   7e-53
gi|93204879 PR domain containing 15 isoform 1 [Homo sapiens]          175   2e-43
gi|222831664 zinc finger protein 184 [Homo sapiens]                   151   3e-36
gi|32698886 zinc finger protein 595 [Homo sapiens]                    150   8e-36
gi|239747149 PREDICTED: hypothetical protein XP_002343926 isofor...   149   1e-35
gi|239747147 PREDICTED: hypothetical protein XP_002343925 isofor...   149   1e-35
gi|239747145 PREDICTED: hypothetical protein XP_002343927 isofor...   149   1e-35
gi|170932473 zinc finger protein 786 [Homo sapiens]                   149   1e-35
gi|188497655 zinc finger protein 84 [Homo sapiens]                    149   1e-35
gi|188497653 zinc finger protein 84 [Homo sapiens]                    149   1e-35
gi|197313746 zinc finger protein 502 [Homo sapiens]                   147   5e-35
gi|197313744 zinc finger protein 502 [Homo sapiens]                   147   5e-35
gi|197313742 zinc finger protein 502 [Homo sapiens]                   147   5e-35
gi|21361857 zinc finger protein 502 [Homo sapiens]                    147   5e-35
gi|172072608 zinc finger protein 624 [Homo sapiens]                   147   7e-35
gi|48717241 zinc finger protein 425 [Homo sapiens]                    147   7e-35
gi|72384335 zinc finger protein 311 [Homo sapiens]                    146   1e-34
gi|7662424 zinc finger protein 510 [Homo sapiens]                     145   1e-34
gi|55769561 zinc finger protein 21 isoform 2 [Homo sapiens]           145   1e-34
gi|55769559 zinc finger protein 21 isoform 1 [Homo sapiens]           145   1e-34
gi|34303941 zinc finger protein 567 [Homo sapiens]                    145   1e-34
gi|22095393 zinc finger protein 420 [Homo sapiens]                    144   4e-34
gi|210031219 zinc finger protein 845 [Homo sapiens]                   144   4e-34
gi|38570117 zinc finger protein 569 [Homo sapiens]                    144   6e-34
gi|89001105 zinc finger protein 571 [Homo sapiens]                    143   9e-34
gi|155722996 zinc finger protein 544 [Homo sapiens]                   142   1e-33

>gi|41349464 PR domain containing 10 isoform 4 [Homo sapiens]
          Length = 1023

 Score = 2114 bits (5477), Expect = 0.0
 Identities = 1023/1023 (100%), Positives = 1023/1023 (100%)

Query: 1    MSAYSVPSTFAQASLPVHNQVLPSIESVDGSDPLATLQTPLGRLEAKEEEDEDEDEDTEE 60
            MSAYSVPSTFAQASLPVHNQVLPSIESVDGSDPLATLQTPLGRLEAKEEEDEDEDEDTEE
Sbjct: 1    MSAYSVPSTFAQASLPVHNQVLPSIESVDGSDPLATLQTPLGRLEAKEEEDEDEDEDTEE 60

Query: 61   DEEEDGEDTDLDDWEPDPPRPFDPHDLWCEECNNAHASVCPKHGPLHPIPNRPVLTRARA 120
            DEEEDGEDTDLDDWEPDPPRPFDPHDLWCEECNNAHASVCPKHGPLHPIPNRPVLTRARA
Sbjct: 61   DEEEDGEDTDLDDWEPDPPRPFDPHDLWCEECNNAHASVCPKHGPLHPIPNRPVLTRARA 120

Query: 121  SLPLVLYIDRFLGGVFSKRRIPKRTQFGPVEGPLVRGSELKDCYIHLKVSLDKGDRKERD 180
            SLPLVLYIDRFLGGVFSKRRIPKRTQFGPVEGPLVRGSELKDCYIHLKVSLDKGDRKERD
Sbjct: 121  SLPLVLYIDRFLGGVFSKRRIPKRTQFGPVEGPLVRGSELKDCYIHLKVSLDKGDRKERD 180

Query: 181  LHEDLWFELSDETLCNWMMFVRPAQNHLEQNLVAYQYGHHVYYTTIKNVEPKQELKVWYA 240
            LHEDLWFELSDETLCNWMMFVRPAQNHLEQNLVAYQYGHHVYYTTIKNVEPKQELKVWYA
Sbjct: 181  LHEDLWFELSDETLCNWMMFVRPAQNHLEQNLVAYQYGHHVYYTTIKNVEPKQELKVWYA 240

Query: 241  ASYAEFVNQKIHDISEEERKVLREQEKNWPCYECNRRFISSEQLQQHLNSHDEKLDVFSR 300
            ASYAEFVNQKIHDISEEERKVLREQEKNWPCYECNRRFISSEQLQQHLNSHDEKLDVFSR
Sbjct: 241  ASYAEFVNQKIHDISEEERKVLREQEKNWPCYECNRRFISSEQLQQHLNSHDEKLDVFSR 300

Query: 301  TRGRGRGRGKRRFGPGRRPGRPPKFIRLEITSENGEKSDDGTQDLLHFPTKEQFDEAEPA 360
            TRGRGRGRGKRRFGPGRRPGRPPKFIRLEITSENGEKSDDGTQDLLHFPTKEQFDEAEPA
Sbjct: 301  TRGRGRGRGKRRFGPGRRPGRPPKFIRLEITSENGEKSDDGTQDLLHFPTKEQFDEAEPA 360

Query: 361  TLNGLDQPEQTTIPIPQLPQETQSSLEHEPETHTLHLQPQHEESVVPTQSTLTADDMRRA 420
            TLNGLDQPEQTTIPIPQLPQETQSSLEHEPETHTLHLQPQHEESVVPTQSTLTADDMRRA
Sbjct: 361  TLNGLDQPEQTTIPIPQLPQETQSSLEHEPETHTLHLQPQHEESVVPTQSTLTADDMRRA 420

Query: 421  KRIRNAALQHLFIRKSFRPFKCLQCGKAFREKDKLDQHLRFHGREGNCPLTCDLCNKGFI 480
            KRIRNAALQHLFIRKSFRPFKCLQCGKAFREKDKLDQHLRFHGREGNCPLTCDLCNKGFI
Sbjct: 421  KRIRNAALQHLFIRKSFRPFKCLQCGKAFREKDKLDQHLRFHGREGNCPLTCDLCNKGFI 480

Query: 481  SSTSLESHMKLHSDQKTYSCIFCPESFDRLDLLKDHVAIHINDGYFTCPTCKKRFPDFIQ 540
            SSTSLESHMKLHSDQKTYSCIFCPESFDRLDLLKDHVAIHINDGYFTCPTCKKRFPDFIQ
Sbjct: 481  SSTSLESHMKLHSDQKTYSCIFCPESFDRLDLLKDHVAIHINDGYFTCPTCKKRFPDFIQ 540

Query: 541  VKKHVRSFHSEKIYQCTECDKAFCRPDKLRLHMLRHSDRKDFLCSTCGKQFKRKDKLREH 600
            VKKHVRSFHSEKIYQCTECDKAFCRPDKLRLHMLRHSDRKDFLCSTCGKQFKRKDKLREH
Sbjct: 541  VKKHVRSFHSEKIYQCTECDKAFCRPDKLRLHMLRHSDRKDFLCSTCGKQFKRKDKLREH 600

Query: 601  MQRMHNPEREAKKADRISRSKTFKPRITSTDYDSFTFKCRLCMMGFRRRGMLVNHLSKRH 660
            MQRMHNPEREAKKADRISRSKTFKPRITSTDYDSFTFKCRLCMMGFRRRGMLVNHLSKRH
Sbjct: 601  MQRMHNPEREAKKADRISRSKTFKPRITSTDYDSFTFKCRLCMMGFRRRGMLVNHLSKRH 660

Query: 661  PDMKIEEVPELTLPIIKPNRDYFCQYCDKVYKSASKRKAHILKNHPGAELPPSIRKLRPA 720
            PDMKIEEVPELTLPIIKPNRDYFCQYCDKVYKSASKRKAHILKNHPGAELPPSIRKLRPA
Sbjct: 661  PDMKIEEVPELTLPIIKPNRDYFCQYCDKVYKSASKRKAHILKNHPGAELPPSIRKLRPA 720

Query: 721  GPGEPDPMLSTHTQLTGTIATPPVCCPHCSKQYSSKTKMVQHIRKKHPEFAQLSNTIHTP 780
            GPGEPDPMLSTHTQLTGTIATPPVCCPHCSKQYSSKTKMVQHIRKKHPEFAQLSNTIHTP
Sbjct: 721  GPGEPDPMLSTHTQLTGTIATPPVCCPHCSKQYSSKTKMVQHIRKKHPEFAQLSNTIHTP 780

Query: 781  LTTAVISATPAVLTTDSATGETVVTTDLLTQAMTELSQTLTTDYRTPQGDYQRIQYIPVS 840
            LTTAVISATPAVLTTDSATGETVVTTDLLTQAMTELSQTLTTDYRTPQGDYQRIQYIPVS
Sbjct: 781  LTTAVISATPAVLTTDSATGETVVTTDLLTQAMTELSQTLTTDYRTPQGDYQRIQYIPVS 840

Query: 841  QSASGLQQPQHIQLQVVQVASVSGQPLSPSAQQAQQGLSPSHIQGSSSTQGQALQQQQQQ 900
            QSASGLQQPQHIQLQVVQVASVSGQPLSPSAQQAQQGLSPSHIQGSSSTQGQALQQQQQQ
Sbjct: 841  QSASGLQQPQHIQLQVVQVASVSGQPLSPSAQQAQQGLSPSHIQGSSSTQGQALQQQQQQ 900

Query: 901  QQNSSVQHTYLPSAWNSFRGYSSEIQMMTLPPGQFVITDSGVATPVTTGQVKAVTSGHYV 960
            QQNSSVQHTYLPSAWNSFRGYSSEIQMMTLPPGQFVITDSGVATPVTTGQVKAVTSGHYV
Sbjct: 901  QQNSSVQHTYLPSAWNSFRGYSSEIQMMTLPPGQFVITDSGVATPVTTGQVKAVTSGHYV 960

Query: 961  LSESQSELEEKQTSALSGGVQVEPPAHSDSLDPQTNSQQQTTQYIITTTTNGNGSSEVHI 1020
            LSESQSELEEKQTSALSGGVQVEPPAHSDSLDPQTNSQQQTTQYIITTTTNGNGSSEVHI
Sbjct: 961  LSESQSELEEKQTSALSGGVQVEPPAHSDSLDPQTNSQQQTTQYIITTTTNGNGSSEVHI 1020

Query: 1021 TKP 1023
            TKP
Sbjct: 1021 TKP 1023


>gi|41349462 PR domain containing 10 isoform 3 [Homo sapiens]
          Length = 1061

 Score = 2091 bits (5417), Expect = 0.0
 Identities = 1023/1061 (96%), Positives = 1023/1061 (96%), Gaps = 38/1061 (3%)

Query: 1    MSAYSVPSTFAQASLPVHNQVLPSIESVDGSDPLATLQTPLGRLEAKEEEDEDEDEDTEE 60
            MSAYSVPSTFAQASLPVHNQVLPSIESVDGSDPLATLQTPLGRLEAKEEEDEDEDEDTEE
Sbjct: 1    MSAYSVPSTFAQASLPVHNQVLPSIESVDGSDPLATLQTPLGRLEAKEEEDEDEDEDTEE 60

Query: 61   DEEEDGEDTDLDDWEPDPPRPFDPHDLWCEECNNAHASVCPKHGPLHPIPNRPVLTRARA 120
            DEEEDGEDTDLDDWEPDPPRPFDPHDLWCEECNNAHASVCPKHGPLHPIPNRPVLTRARA
Sbjct: 61   DEEEDGEDTDLDDWEPDPPRPFDPHDLWCEECNNAHASVCPKHGPLHPIPNRPVLTRARA 120

Query: 121  SLPLVLYIDRFLGGVFSKRRIPKRTQFGPVEGPLVRGSELKDCYIHLKVSLDKGDRKERD 180
            SLPLVLYIDRFLGGVFSKRRIPKRTQFGPVEGPLVRGSELKDCYIHLKVSLDKGDRKERD
Sbjct: 121  SLPLVLYIDRFLGGVFSKRRIPKRTQFGPVEGPLVRGSELKDCYIHLKVSLDKGDRKERD 180

Query: 181  LHEDLWFELSDETLCNWMMFVRPAQNHLEQNLVAYQYGHHVYYTTIKNVEPKQELKVWYA 240
            LHEDLWFELSDETLCNWMMFVRPAQNHLEQNLVAYQYGHHVYYTTIKNVEPKQELKVWYA
Sbjct: 181  LHEDLWFELSDETLCNWMMFVRPAQNHLEQNLVAYQYGHHVYYTTIKNVEPKQELKVWYA 240

Query: 241  ASYAEFVNQKIHDISEEERKVLREQEKNWPCYECNRRFISSEQLQQHLNSHDEKLDVFSR 300
            ASYAEFVNQKIHDISEEERKVLREQEKNWPCYECNRRFISSEQLQQHLNSHDEKLDVFSR
Sbjct: 241  ASYAEFVNQKIHDISEEERKVLREQEKNWPCYECNRRFISSEQLQQHLNSHDEKLDVFSR 300

Query: 301  TRGRGRGRGKRRFGPGRRPGRPPKFIRLEITSENGEKSDDGTQDLLHFPTKEQFDEAEPA 360
            TRGRGRGRGKRRFGPGRRPGRPPKFIRLEITSENGEKSDDGTQDLLHFPTKEQFDEAEPA
Sbjct: 301  TRGRGRGRGKRRFGPGRRPGRPPKFIRLEITSENGEKSDDGTQDLLHFPTKEQFDEAEPA 360

Query: 361  TLNGLDQPEQTTIPIPQLPQETQSSLEHEPETHTLHLQPQHEESVVPTQSTLTADDMRRA 420
            TLNGLDQPEQTTIPIPQLPQETQSSLEHEPETHTLHLQPQHEESVVPTQSTLTADDMRRA
Sbjct: 361  TLNGLDQPEQTTIPIPQLPQETQSSLEHEPETHTLHLQPQHEESVVPTQSTLTADDMRRA 420

Query: 421  KRIR----NAALQHLFIRKSFRPFKCLQCGKAFREKDKLDQHLRFHGREGNCPLTCDLCN 476
            KRIR    NAALQHLFIRKSFRPFKCLQCGKAFREKDKLDQHLRFHGREGNCPLTCDLCN
Sbjct: 421  KRIRLELQNAALQHLFIRKSFRPFKCLQCGKAFREKDKLDQHLRFHGREGNCPLTCDLCN 480

Query: 477  KGFISSTSLESHMKLHSDQKTYSCIFCPESFDRLDLLKDHVAIHINDGYFTCPTCKKRFP 536
            KGFISSTSLESHMKLHSDQKTYSCIFCPESFDRLDLLKDHVAIHINDGYFTCPTCKKRFP
Sbjct: 481  KGFISSTSLESHMKLHSDQKTYSCIFCPESFDRLDLLKDHVAIHINDGYFTCPTCKKRFP 540

Query: 537  DFIQVKKHVRSFHSEKIYQCTECDKAFCRPDKLRLHMLRHSDRKDFLCSTCGKQFKRKDK 596
            DFIQVKKHVRSFHSEKIYQCTECDKAFCRPDKLRLHMLRHSDRKDFLCSTCGKQFKRKDK
Sbjct: 541  DFIQVKKHVRSFHSEKIYQCTECDKAFCRPDKLRLHMLRHSDRKDFLCSTCGKQFKRKDK 600

Query: 597  LREHMQRMHNPEREAKKADRISRSKTFKPRITSTDYDSFTFKCRLCMMGFRRRGMLVNHL 656
            LREHMQRMHNPEREAKKADRISRSKTFKPRITSTDYDSFTFKCRLCMMGFRRRGMLVNHL
Sbjct: 601  LREHMQRMHNPEREAKKADRISRSKTFKPRITSTDYDSFTFKCRLCMMGFRRRGMLVNHL 660

Query: 657  SKRHPDMKIEEVPELTLPIIKPNRDYFCQYCDKVYKSASKRKAHILKNHPGAELPPSIRK 716
            SKRHPDMKIEEVPELTLPIIKPNRDYFCQYCDKVYKSASKRKAHILKNHPGAELPPSIRK
Sbjct: 661  SKRHPDMKIEEVPELTLPIIKPNRDYFCQYCDKVYKSASKRKAHILKNHPGAELPPSIRK 720

Query: 717  LRPAGPGEPDPMLSTHTQLTGTIATPPVCCPHCSKQYSSKTKMVQHIRKKHPEFAQLSNT 776
            LRPAGPGEPDPMLSTHTQLTGTIATPPVCCPHCSKQYSSKTKMVQHIRKKHPEFAQLSNT
Sbjct: 721  LRPAGPGEPDPMLSTHTQLTGTIATPPVCCPHCSKQYSSKTKMVQHIRKKHPEFAQLSNT 780

Query: 777  IHTPLTTAVISATPAVLTTDSATGETVVTTDLLTQAMTELSQTLTTDYRTPQGDYQRIQY 836
            IHTPLTTAVISATPAVLTTDSATGETVVTTDLLTQAMTELSQTLTTDYRTPQGDYQRIQY
Sbjct: 781  IHTPLTTAVISATPAVLTTDSATGETVVTTDLLTQAMTELSQTLTTDYRTPQGDYQRIQY 840

Query: 837  IPVSQSASGLQQPQHIQLQVVQVAS----------------------------------V 862
            IPVSQSASGLQQPQHIQLQVVQVAS                                  V
Sbjct: 841  IPVSQSASGLQQPQHIQLQVVQVASATSPHQSQQSTVDVGQLHDPQPYPQHAIQVQHIQV 900

Query: 863  SGQPLSPSAQQAQQGLSPSHIQGSSSTQGQALQQQQQQQQNSSVQHTYLPSAWNSFRGYS 922
            SGQPLSPSAQQAQQGLSPSHIQGSSSTQGQALQQQQQQQQNSSVQHTYLPSAWNSFRGYS
Sbjct: 901  SGQPLSPSAQQAQQGLSPSHIQGSSSTQGQALQQQQQQQQNSSVQHTYLPSAWNSFRGYS 960

Query: 923  SEIQMMTLPPGQFVITDSGVATPVTTGQVKAVTSGHYVLSESQSELEEKQTSALSGGVQV 982
            SEIQMMTLPPGQFVITDSGVATPVTTGQVKAVTSGHYVLSESQSELEEKQTSALSGGVQV
Sbjct: 961  SEIQMMTLPPGQFVITDSGVATPVTTGQVKAVTSGHYVLSESQSELEEKQTSALSGGVQV 1020

Query: 983  EPPAHSDSLDPQTNSQQQTTQYIITTTTNGNGSSEVHITKP 1023
            EPPAHSDSLDPQTNSQQQTTQYIITTTTNGNGSSEVHITKP
Sbjct: 1021 EPPAHSDSLDPQTNSQQQTTQYIITTTTNGNGSSEVHITKP 1061


>gi|41349460 PR domain containing 10 isoform 2 [Homo sapiens]
          Length = 1156

 Score = 2072 bits (5368), Expect = 0.0
 Identities = 1013/1063 (95%), Positives = 1014/1063 (95%), Gaps = 47/1063 (4%)

Query: 8    STFAQASLPVHNQVLPSIESVDGSDPLATLQTPLGRLEAKEEEDEDEDEDTEEDEEEDGE 67
            +T  QASLPVHNQVLPSIESVDGSDPLATLQTPLGRLEAKEEEDEDEDEDTEEDEEEDGE
Sbjct: 94   ATAQQASLPVHNQVLPSIESVDGSDPLATLQTPLGRLEAKEEEDEDEDEDTEEDEEEDGE 153

Query: 68   DTDLDDWEPDPPRPFDPHDLWCEECNNAHASVCPKHGPLHPIPNRPVLTRARASLPLVLY 127
            DTDLDDWEPDPPRPFDPHDLWCEECNNAHASVCPKHGPLHPIPNRPVLTRARASLPLVLY
Sbjct: 154  DTDLDDWEPDPPRPFDPHDLWCEECNNAHASVCPKHGPLHPIPNRPVLTRARASLPLVLY 213

Query: 128  IDRFLGGVFSKRRIPKRTQFGPVEGPLVRGSELKDCYIHLKVSLDKGDRKERDLHEDLWF 187
            IDRFLGGVFSKRRIPKRTQFGPVEGPLVRGSELKDCYIHLKVSLDKGDRKERDLHEDLWF
Sbjct: 214  IDRFLGGVFSKRRIPKRTQFGPVEGPLVRGSELKDCYIHLKVSLDKGDRKERDLHEDLWF 273

Query: 188  ELSDETLCNWMMFVRPAQNHLEQNLVAYQYGHHVYYTTIKNVEPKQELKVWYAASYAEFV 247
            ELSDETLCNWMMFVRPAQNHLEQNLVAYQYGHHVYYTTIKNVEPKQELKVWYAASYAEFV
Sbjct: 274  ELSDETLCNWMMFVRPAQNHLEQNLVAYQYGHHVYYTTIKNVEPKQELKVWYAASYAEFV 333

Query: 248  NQKIHDISEEERKVLREQEKNWPCYECNRRFISSEQLQQHLNSHDEKLDVFSRTRGRGRG 307
            NQKIHDISEEERKVLREQEKNWPCYECNRRFISSEQLQQHLNSHDEKLDVFSRTRGRGRG
Sbjct: 334  NQKIHDISEEERKVLREQEKNWPCYECNRRFISSEQLQQHLNSHDEKLDVFSRTRGRGRG 393

Query: 308  RGKRRFGPGRRPGRPPKFIRLEITSENGEKSDDGTQDLLHFPTKEQFDEAEPATLNGLDQ 367
            RGKRRFGPGRRPGRPPKFIRLEITSENGEKSDDGTQDLLHFPTKEQFDEAEPATLNGLDQ
Sbjct: 394  RGKRRFGPGRRPGRPPKFIRLEITSENGEKSDDGTQDLLHFPTKEQFDEAEPATLNGLDQ 453

Query: 368  PEQTTIPIPQLPQETQSSLEHEPETHTLHLQPQHEESVVPTQSTLTADDMRRAKRIRNAA 427
            PEQTTIPIPQLPQETQSSLEHEPETHTLHLQPQHEESVVPTQSTLTADDMRRAKRIRNAA
Sbjct: 454  PEQTTIPIPQLPQETQSSLEHEPETHTLHLQPQHEESVVPTQSTLTADDMRRAKRIRNAA 513

Query: 428  LQHLFIRKSFRPFKCLQCGKAFREKDKLDQHLRFHGREGNCPLTCDLCNKGFISSTSLES 487
            LQHLFIRKSFRPFKCLQCGKAFREKDKLDQHLRFHGREGNCPLTCDLCNKGFISSTSLES
Sbjct: 514  LQHLFIRKSFRPFKCLQCGKAFREKDKLDQHLRFHGREGNCPLTCDLCNKGFISSTSLES 573

Query: 488  HMKLHSDQKTYSCIFCPESFDRLDLLKDHVAIHINDGYFTCPTCKKRFPDFIQVKKHVRS 547
            HMKLHSDQKTYSCIFCPESFDRLDLLKDHVAIHINDGYFTCPTCKKRFPDFIQVKKHVRS
Sbjct: 574  HMKLHSDQKTYSCIFCPESFDRLDLLKDHVAIHINDGYFTCPTCKKRFPDFIQVKKHVRS 633

Query: 548  FHSEKIYQCTECDKAFCRPDKLRLHMLRHSDRKDFLCSTCGKQFKRKDKLREHMQRMHNP 607
            FHSEKIYQCTECDKAFCRPDKLRLHMLRHSDRKDFLCSTCGKQFKRKDKLREHMQRMHNP
Sbjct: 634  FHSEKIYQCTECDKAFCRPDKLRLHMLRHSDRKDFLCSTCGKQFKRKDKLREHMQRMHNP 693

Query: 608  EREAKKADRISRSKTFKPRITSTDYDSFTFKCRLCMMGFRRRGMLVNHLSKRHPDMKIEE 667
            EREAKKADRISRSKTFKPRITSTDYDSFTFKCRLCMMGFRRRGMLVNHLSKRHPDMKIEE
Sbjct: 694  EREAKKADRISRSKTFKPRITSTDYDSFTFKCRLCMMGFRRRGMLVNHLSKRHPDMKIEE 753

Query: 668  VPELTLPIIKPNRDYFCQYCDKVYKSASKRKAHILKNHPGAELPPSIRKLRPAGPGEPDP 727
            VPELTLPIIKPNRDYFCQYCDKVYKSASKRKAHILKNHPGAELPPSIRKLRPAGPGEPDP
Sbjct: 754  VPELTLPIIKPNRDYFCQYCDKVYKSASKRKAHILKNHPGAELPPSIRKLRPAGPGEPDP 813

Query: 728  MLSTHTQLTGTIATPPVCCPHCSKQYSSKTKMVQHIRKKHPEFAQLSNTIHTPLTTAVIS 787
            MLSTHTQLTGTIATPPVCCPHCSKQYSSKTKMVQHIRKKHPEFAQLSNTIHTPLTTAVIS
Sbjct: 814  MLSTHTQLTGTIATPPVCCPHCSKQYSSKTKMVQHIRKKHPEFAQLSNTIHTPLTTAVIS 873

Query: 788  ATPAVLTTDSATGETVVTTDLLTQAMTELSQTLTTDYRTPQGDYQRIQYIPVSQSASGLQ 847
            ATPAVLTTDSATGETVVTTDLLTQAMTELSQTLTTDYRTPQGDYQRIQYIPVSQSASGLQ
Sbjct: 874  ATPAVLTTDSATGETVVTTDLLTQAMTELSQTLTTDYRTPQGDYQRIQYIPVSQSASGLQ 933

Query: 848  QPQHIQLQVVQVAS---------------------------------------------- 861
            QPQHIQLQVVQVAS                                              
Sbjct: 934  QPQHIQLQVVQVASATSPHQSQQSTVDVGQLHDPQPYPQHAIQVQHIQVSEPTASAPSSA 993

Query: 862  -VSGQPLSPSAQQAQQGLSPSHIQGSSSTQGQALQQQQQQQQNSSVQHTYLPSAWNSFRG 920
             VSGQPLSPSAQQAQQGLSPSHIQGSSSTQGQALQQQQQQQQNSSVQHTYLPSAWNSFRG
Sbjct: 994  QVSGQPLSPSAQQAQQGLSPSHIQGSSSTQGQALQQQQQQQQNSSVQHTYLPSAWNSFRG 1053

Query: 921  YSSEIQMMTLPPGQFVITDSGVATPVTTGQVKAVTSGHYVLSESQSELEEKQTSALSGGV 980
            YSSEIQMMTLPPGQFVITDSGVATPVTTGQVKAVTSGHYVLSESQSELEEKQTSALSGGV
Sbjct: 1054 YSSEIQMMTLPPGQFVITDSGVATPVTTGQVKAVTSGHYVLSESQSELEEKQTSALSGGV 1113

Query: 981  QVEPPAHSDSLDPQTNSQQQTTQYIITTTTNGNGSSEVHITKP 1023
            QVEPPAHSDSLDPQTNSQQQTTQYIITTTTNGNGSSEVHITKP
Sbjct: 1114 QVEPPAHSDSLDPQTNSQQQTTQYIITTTTNGNGSSEVHITKP 1156


>gi|41349458 PR domain containing 10 isoform 1 [Homo sapiens]
          Length = 1160

 Score = 2066 bits (5353), Expect = 0.0
 Identities = 1013/1067 (94%), Positives = 1014/1067 (95%), Gaps = 51/1067 (4%)

Query: 8    STFAQASLPVHNQVLPSIESVDGSDPLATLQTPLGRLEAKEEEDEDEDEDTEEDEEEDGE 67
            +T  QASLPVHNQVLPSIESVDGSDPLATLQTPLGRLEAKEEEDEDEDEDTEEDEEEDGE
Sbjct: 94   ATAQQASLPVHNQVLPSIESVDGSDPLATLQTPLGRLEAKEEEDEDEDEDTEEDEEEDGE 153

Query: 68   DTDLDDWEPDPPRPFDPHDLWCEECNNAHASVCPKHGPLHPIPNRPVLTRARASLPLVLY 127
            DTDLDDWEPDPPRPFDPHDLWCEECNNAHASVCPKHGPLHPIPNRPVLTRARASLPLVLY
Sbjct: 154  DTDLDDWEPDPPRPFDPHDLWCEECNNAHASVCPKHGPLHPIPNRPVLTRARASLPLVLY 213

Query: 128  IDRFLGGVFSKRRIPKRTQFGPVEGPLVRGSELKDCYIHLKVSLDKGDRKERDLHEDLWF 187
            IDRFLGGVFSKRRIPKRTQFGPVEGPLVRGSELKDCYIHLKVSLDKGDRKERDLHEDLWF
Sbjct: 214  IDRFLGGVFSKRRIPKRTQFGPVEGPLVRGSELKDCYIHLKVSLDKGDRKERDLHEDLWF 273

Query: 188  ELSDETLCNWMMFVRPAQNHLEQNLVAYQYGHHVYYTTIKNVEPKQELKVWYAASYAEFV 247
            ELSDETLCNWMMFVRPAQNHLEQNLVAYQYGHHVYYTTIKNVEPKQELKVWYAASYAEFV
Sbjct: 274  ELSDETLCNWMMFVRPAQNHLEQNLVAYQYGHHVYYTTIKNVEPKQELKVWYAASYAEFV 333

Query: 248  NQKIHDISEEERKVLREQEKNWPCYECNRRFISSEQLQQHLNSHDEKLDVFSRTRGRGRG 307
            NQKIHDISEEERKVLREQEKNWPCYECNRRFISSEQLQQHLNSHDEKLDVFSRTRGRGRG
Sbjct: 334  NQKIHDISEEERKVLREQEKNWPCYECNRRFISSEQLQQHLNSHDEKLDVFSRTRGRGRG 393

Query: 308  RGKRRFGPGRRPGRPPKFIRLEITSENGEKSDDGTQDLLHFPTKEQFDEAEPATLNGLDQ 367
            RGKRRFGPGRRPGRPPKFIRLEITSENGEKSDDGTQDLLHFPTKEQFDEAEPATLNGLDQ
Sbjct: 394  RGKRRFGPGRRPGRPPKFIRLEITSENGEKSDDGTQDLLHFPTKEQFDEAEPATLNGLDQ 453

Query: 368  PEQTTIPIPQLPQETQSSLEHEPETHTLHLQPQHEESVVPTQSTLTADDMRRAKRIR--- 424
            PEQTTIPIPQLPQETQSSLEHEPETHTLHLQPQHEESVVPTQSTLTADDMRRAKRIR   
Sbjct: 454  PEQTTIPIPQLPQETQSSLEHEPETHTLHLQPQHEESVVPTQSTLTADDMRRAKRIRLEL 513

Query: 425  -NAALQHLFIRKSFRPFKCLQCGKAFREKDKLDQHLRFHGREGNCPLTCDLCNKGFISST 483
             NAALQHLFIRKSFRPFKCLQCGKAFREKDKLDQHLRFHGREGNCPLTCDLCNKGFISST
Sbjct: 514  QNAALQHLFIRKSFRPFKCLQCGKAFREKDKLDQHLRFHGREGNCPLTCDLCNKGFISST 573

Query: 484  SLESHMKLHSDQKTYSCIFCPESFDRLDLLKDHVAIHINDGYFTCPTCKKRFPDFIQVKK 543
            SLESHMKLHSDQKTYSCIFCPESFDRLDLLKDHVAIHINDGYFTCPTCKKRFPDFIQVKK
Sbjct: 574  SLESHMKLHSDQKTYSCIFCPESFDRLDLLKDHVAIHINDGYFTCPTCKKRFPDFIQVKK 633

Query: 544  HVRSFHSEKIYQCTECDKAFCRPDKLRLHMLRHSDRKDFLCSTCGKQFKRKDKLREHMQR 603
            HVRSFHSEKIYQCTECDKAFCRPDKLRLHMLRHSDRKDFLCSTCGKQFKRKDKLREHMQR
Sbjct: 634  HVRSFHSEKIYQCTECDKAFCRPDKLRLHMLRHSDRKDFLCSTCGKQFKRKDKLREHMQR 693

Query: 604  MHNPEREAKKADRISRSKTFKPRITSTDYDSFTFKCRLCMMGFRRRGMLVNHLSKRHPDM 663
            MHNPEREAKKADRISRSKTFKPRITSTDYDSFTFKCRLCMMGFRRRGMLVNHLSKRHPDM
Sbjct: 694  MHNPEREAKKADRISRSKTFKPRITSTDYDSFTFKCRLCMMGFRRRGMLVNHLSKRHPDM 753

Query: 664  KIEEVPELTLPIIKPNRDYFCQYCDKVYKSASKRKAHILKNHPGAELPPSIRKLRPAGPG 723
            KIEEVPELTLPIIKPNRDYFCQYCDKVYKSASKRKAHILKNHPGAELPPSIRKLRPAGPG
Sbjct: 754  KIEEVPELTLPIIKPNRDYFCQYCDKVYKSASKRKAHILKNHPGAELPPSIRKLRPAGPG 813

Query: 724  EPDPMLSTHTQLTGTIATPPVCCPHCSKQYSSKTKMVQHIRKKHPEFAQLSNTIHTPLTT 783
            EPDPMLSTHTQLTGTIATPPVCCPHCSKQYSSKTKMVQHIRKKHPEFAQLSNTIHTPLTT
Sbjct: 814  EPDPMLSTHTQLTGTIATPPVCCPHCSKQYSSKTKMVQHIRKKHPEFAQLSNTIHTPLTT 873

Query: 784  AVISATPAVLTTDSATGETVVTTDLLTQAMTELSQTLTTDYRTPQGDYQRIQYIPVSQSA 843
            AVISATPAVLTTDSATGETVVTTDLLTQAMTELSQTLTTDYRTPQGDYQRIQYIPVSQSA
Sbjct: 874  AVISATPAVLTTDSATGETVVTTDLLTQAMTELSQTLTTDYRTPQGDYQRIQYIPVSQSA 933

Query: 844  SGLQQPQHIQLQVVQVAS------------------------------------------ 861
            SGLQQPQHIQLQVVQVAS                                          
Sbjct: 934  SGLQQPQHIQLQVVQVASATSPHQSQQSTVDVGQLHDPQPYPQHAIQVQHIQVSEPTASA 993

Query: 862  -----VSGQPLSPSAQQAQQGLSPSHIQGSSSTQGQALQQQQQQQQNSSVQHTYLPSAWN 916
                 VSGQPLSPSAQQAQQGLSPSHIQGSSSTQGQALQQQQQQQQNSSVQHTYLPSAWN
Sbjct: 994  PSSAQVSGQPLSPSAQQAQQGLSPSHIQGSSSTQGQALQQQQQQQQNSSVQHTYLPSAWN 1053

Query: 917  SFRGYSSEIQMMTLPPGQFVITDSGVATPVTTGQVKAVTSGHYVLSESQSELEEKQTSAL 976
            SFRGYSSEIQMMTLPPGQFVITDSGVATPVTTGQVKAVTSGHYVLSESQSELEEKQTSAL
Sbjct: 1054 SFRGYSSEIQMMTLPPGQFVITDSGVATPVTTGQVKAVTSGHYVLSESQSELEEKQTSAL 1113

Query: 977  SGGVQVEPPAHSDSLDPQTNSQQQTTQYIITTTTNGNGSSEVHITKP 1023
            SGGVQVEPPAHSDSLDPQTNSQQQTTQYIITTTTNGNGSSEVHITKP
Sbjct: 1114 SGGVQVEPPAHSDSLDPQTNSQQQTTQYIITTTTNGNGSSEVHITKP 1160


>gi|94536868 PR domain containing 15 isoform 2 [Homo sapiens]
          Length = 1178

 Score =  206 bits (525), Expect = 7e-53
 Identities = 201/772 (26%), Positives = 305/772 (39%), Gaps = 139/772 (18%)

Query: 87  LWCEECNNAHASVCPKHGPLHPIPNRPVLTRARASLPLVLYIDRF---LGGVFSKRRIPK 143
           +WCE+C+  H S CP+ GP+  + +  VL+RAR+SLP  L I R      GVF+  ++ K
Sbjct: 49  IWCEDCSQYHDSECPELGPVVMVKDSFVLSRARSSLPPNLEIRRLEDGAEGVFAITQLVK 108

Query: 144 RTQFGPVEGPLVRGSELKDCYIHLKVSLDKGDRKERDLHEDLWFELSDETLCNWMMFVRP 203
           RTQFGP E   V   E K+    LKV        ++D H  + F+ S+E  CNWMM VRP
Sbjct: 109 RTQFGPFESRRVAKWE-KESAFPLKVF-------QKDGHP-VCFDTSNEDDCNWMMLVRP 159

Query: 204 AQNHLEQNLVAYQYGHHVYYTTIKNVEPKQELKVWYAASYAEFVNQK--------IHDIS 255
           A     QNL AYQ+G  VY+TT +++ P  EL+VWYAA YA+ +++         +H   
Sbjct: 160 AAEAEHQNLTAYQHGSDVYFTTSRDIPPGTELRVWYAAFYAKKMDKPMLKQAGSGVHAAG 219

Query: 256 EEERKVLREQE-KNWPCYECNRRFISSEQLQQHLNSHDEKL---------DVFSRTRGRG 305
             E     E E   W C  C+  F+  + L +HL  H E+          +  +  + + 
Sbjct: 220 TPENSAPVESEPSQWACKVCSATFLELQLLNEHLLGHLEQAKSLPPGSQSEAAAPEKEQD 279

Query: 306 RGRGKRRFGPGR------------RPGRPPKFIRLE---ITSENGEKSDDGTQDLLHFPT 350
             RG+    P              R GR PK  + E   +  E+ E ++   + +   P 
Sbjct: 280 TPRGEPPAVPESENVATKEQKKKPRRGRKPKVSKAEQPLVIVEDKEPTEQVAEIITEVPP 339

Query: 351 KEQFDEAEPATLNG--LDQPEQTTIPIPQLPQETQSSLEHEPETHTL------------- 395
            E         +    L +   TT     +P+ T     H+  T TL             
Sbjct: 340 DEPVSATPDERIMELVLGKLATTTTDTSSVPKFT----HHQNNTITLKRSLILSSRHGIR 395

Query: 396 -HLQPQHEESVVPTQSTLTADDMRRAKRIRNAALQHLFIRKSFRPFKCLQCGKAFREKDK 454
             L  Q  E     Q  + +   + +  +      H       + FKC +C K F  K+ 
Sbjct: 396 RKLIKQLGEHKRVYQCNICSKIFQNSSNLSRHVRSH-----GDKLFKCEECAKLFSRKES 450

Query: 455 LDQHLRF-HGR---EGNCPLTCDLCNKGFISSTSLESHMKLHSDQKTYSCIFCPESFDRL 510
           L QH+ + H R   +G     C  C K F   ++LE H    +D KT+ C  C   F   
Sbjct: 451 LKQHVSYKHSRNEVDGEYRYRCGTCEKTFRIESALEFH-NCRTDDKTFQCEMCFRFFSTN 509

Query: 511 DLLKDHVAIHINDGYFTCPTCKKRFPDFIQVKKHVRSFHSEKIYQ--------------- 555
             L  H   H  D  F C  C K F     +  H R  H E + +               
Sbjct: 510 SNLSKHKKKH-GDKKFACEVCSKMFYRKDVMLDHQRR-HLEGVRRVKREDLEAGGENLVR 567

Query: 556 -------CTECDKAFCRPDKLRLHMLRHSDRKDFLCSTCGKQFKRKDKLREHMQ------ 602
                  C  C K F     +  H+L H D+K + C  CG++F R D LR+H+       
Sbjct: 568 YKKEPSGCPVCGKVFSCRSNMNKHLLTHGDKK-YTCEICGRKFFRVDVLRDHIHVHFKDI 626

Query: 603 -RMHNPEREAKKAD-RISRSKTFKPRITSTDYDSFTFKCRLCMMGFRRRGMLVNHLSKRH 660
             M + +RE       IS  +       S D +   + C+ C + F R    + H+ + H
Sbjct: 627 ALMDDHQREEFIGKIGISSEENDDNSDESADSEPHKYSCKRCQLTFGRGKEYLKHIMEVH 686

Query: 661 PDMKIEEVPELTLPIIKPNRDYFCQYCDKVYKSASKRKAHIL---KNHPGAELPPSIRKL 717
            +                 + Y C  C++ +   +   AH++   +N P   +   I   
Sbjct: 687 KE-----------------KGYGCSICNRRFALKATYHAHMVIHRENLPDPNVQKYIHPC 729

Query: 718 RPAGP-----GEPDPMLSTHTQLTGTIATPPVCCPHCSKQYSSKTKMVQHIR 764
              G      G  +     HT +          C  C K ++ K  + +H+R
Sbjct: 730 EICGRIFNSIGNLERHKLIHTGVKSH------ACEQCGKSFARKDMLKEHMR 775



 Score =  116 bits (291), Expect = 9e-26
 Identities = 103/450 (22%), Positives = 166/450 (36%), Gaps = 118/450 (26%)

Query: 438 RPFKCLQCGKAFREKDKLDQHLRFH-------------------GREGNCPLTCDLCNKG 478
           + F C  C K F  KD +  H R H                    R    P  C +C K 
Sbjct: 522 KKFACEVCSKMFYRKDVMLDHQRRHLEGVRRVKREDLEAGGENLVRYKKEPSGCPVCGKV 581

Query: 479 FISSTSLESHMKLHSDQKTYSCIFCPESFDRLDLLKDHVAIHIND--------------- 523
           F   +++  H+  H D+K Y+C  C   F R+D+L+DH+ +H  D               
Sbjct: 582 FSCRSNMNKHLLTHGDKK-YTCEICGRKFFRVDVLRDHIHVHFKDIALMDDHQREEFIGK 640

Query: 524 --------------------GYFTCPTCKKRFPDFIQVKKHVRSFHSEKIYQCTECDKAF 563
                                 ++C  C+  F    +  KH+   H EK Y C+ C++ F
Sbjct: 641 IGISSEENDDNSDESADSEPHKYSCKRCQLTFGRGKEYLKHIMEVHKEKGYGCSICNRRF 700

Query: 564 C---------------RPD---------------------KLRLHMLRHSDRKDFLCSTC 587
                            PD                      L  H L H+  K   C  C
Sbjct: 701 ALKATYHAHMVIHRENLPDPNVQKYIHPCEICGRIFNSIGNLERHKLIHTGVKSHACEQC 760

Query: 588 GKQFKRKDKLREHMQRMHNPERE--AKKADRISRSKTFKPRITSTDYDSFTFKCRLCMMG 645
           GK F RKD L+EHM R+H+  RE    +  +  ++K               ++C+ C   
Sbjct: 761 GKSFARKDMLKEHM-RVHDNVREYLCAECGKGMKTKHALRHHMKLHKGIKEYECKECHRR 819

Query: 646 FRRRGMLVNHLSKRHPDMKIEEVPELTLPIIKPNRDYFCQYCDKVYKSASKRKAHILKNH 705
           F ++  ++ H  KRH  +K                D+ C+ C K +   +  + H L + 
Sbjct: 820 FAQKVNMLKH-CKRHTGIK----------------DFMCELCGKTFSERNTMETHKLIHT 862

Query: 706 PGAELPPSIRKLRPAGPGEPDPMLSTHTQLTGTIATPPVCCPHCSKQYSSKTKMVQHIRK 765
            G +   S+   +       + ML  H QLT         C  C  + S++  M +H+R+
Sbjct: 863 VGKQWTCSVCDKKYV----TEYMLQKHVQLTHD-KVEAQSCQLCGTKVSTRASMSRHMRR 917

Query: 766 KHPEF--AQLSNTIHTPLTTAVISATPAVL 793
           KHPE    ++ +  H P TT + +++  ++
Sbjct: 918 KHPEVLAVRIDDLDHLPETTTIDASSIGIV 947



 Score =  110 bits (276), Expect = 5e-24
 Identities = 119/522 (22%), Positives = 202/522 (38%), Gaps = 74/522 (14%)

Query: 428  LQHLFIRKSFRPFKCLQCGKAFREKDKLDQHLRFHGREGNCPLT------CDLCNKGFIS 481
            L+H+      + + C  C + F  K     H+  H      P        C++C + F S
Sbjct: 679  LKHIMEVHKEKGYGCSICNRRFALKATYHAHMVIHRENLPDPNVQKYIHPCEICGRIFNS 738

Query: 482  STSLESHMKLHSDQKTYSCIFCPESFDRLDLLKDHVAIHINDGYFTCPTCKKRFPDFIQV 541
              +LE H  +H+  K+++C  C +SF R D+LK+H+ +H N   + C  C K       +
Sbjct: 739  IGNLERHKLIHTGVKSHACEQCGKSFARKDMLKEHMRVHDNVREYLCAECGKGMKTKHAL 798

Query: 542  KKHVRSFHSEKIYQCTECDKAFCRPDKLRLHMLRHSDRKDFLCSTCGKQFKRKDKLREHM 601
            + H++     K Y+C EC + F +   +  H  RH+  KDF+C  CGK F  ++ +  H 
Sbjct: 799  RHHMKLHKGIKEYECKECHRRFAQKVNMLKHCKRHTGIKDFMCELCGKTFSERNTMETH- 857

Query: 602  QRMHNPERE--AKKADRISRSKTFKPRITSTDYDSFTFK-CRLCMMGFRRRGMLVNHLSK 658
            + +H   ++      D+   ++    +     +D    + C+LC      R  +  H+ +
Sbjct: 858  KLIHTVGKQWTCSVCDKKYVTEYMLQKHVQLTHDKVEAQSCQLCGTKVSTRASMSRHMRR 917

Query: 659  RHPDM------KIEEVPELT------LPIIKPNRDYFCQYCDKVYKSASKRKAHILKNHP 706
            +HP++       ++ +PE T      + I++P      +   +     + +++H  K  P
Sbjct: 918  KHPEVLAVRIDDLDHLPETTTIDASSIGIVQPELTLEQEDLAEGKHGKAAKRSHKRKQKP 977

Query: 707  ----GAELPP-------SIRKLRPAGP--GEPDPMLSTHTQLTGTIATPPVCCPHCSKQY 753
                GA +P        S ++    G    E +  + +  Q+  T+  P V  P  S   
Sbjct: 978  EEEAGAPVPEDATFSEYSEKETEFTGSVGDETNSAVQSIQQVVVTLGDPNVTTPSSS--- 1034

Query: 754  SSKTKMVQHIRKKHPEFAQLSNTIHTPLTTAVISATPAVLTTDSATGETVVTTDLLTQAM 813
                               L+N   TP+TTA  +AT        A G  + T +   Q  
Sbjct: 1035 -----------------VGLTNITVTPITTA--AATQFTNLQPVAVGH-LTTPERQLQLD 1074

Query: 814  TELSQTLTTDYRTPQG-----DYQRIQYIPVSQSASGLQQPQHIQLQVVQVASVS----- 863
              +   LT  + T  G     + Q    I     AS  Q   H       V S++     
Sbjct: 1075 NSI---LTVTFDTVSGSAMLHNRQNDVQIHPQPEASNPQSVAHFINLTTLVNSITPLGSQ 1131

Query: 864  ---GQPLSPSAQQAQQGLSPSHIQGSSSTQGQALQQQQQQQQ 902
                 PL+  A      L PS  Q       Q   Q +QQQQ
Sbjct: 1132 LSDQHPLTWRAVPQTDVLPPSQPQAPPQQAAQPQVQAEQQQQ 1173



 Score = 32.7 bits (73), Expect = 1.8
 Identities = 39/163 (23%), Positives = 63/163 (38%), Gaps = 33/163 (20%)

Query: 257 EERKVLREQEKNWPCYECNRRFISSEQLQQHLNSHDEKLDVFS----RTRGRGRGRGKRR 312
           E  K++    K W C  C++++++   LQ+H+    +K++  S     T+   R    R 
Sbjct: 855 ETHKLIHTVGKQWTCSVCDKKYVTEYMLQKHVQLTHDKVEAQSCQLCGTKVSTRASMSRH 914

Query: 313 FGPGRRPGRPPKFIRLEITSENGEKSDDGTQDLLHFPTKEQFDEAEPATLNGLDQPEQTT 372
               RR  + P+ + + I             DL H P     D    A+  G+ QPE T 
Sbjct: 915 M---RR--KHPEVLAVRI------------DDLDHLPETTTID----ASSIGIVQPELT- 952

Query: 373 IPIPQLPQETQSSLEHEPETHTLHLQPQ--HEESVVPTQSTLT 413
                L QE  +  +H       H + Q   EE+  P     T
Sbjct: 953 -----LEQEDLAEGKHGKAAKRSHKRKQKPEEEAGAPVPEDAT 990



 Score = 31.6 bits (70), Expect = 4.0
 Identities = 12/49 (24%), Positives = 23/49 (46%)

Query: 257 EERKVLREQEKNWPCYECNRRFISSEQLQQHLNSHDEKLDVFSRTRGRG 305
           E  K++    K+  C +C + F   + L++H+  HD   +      G+G
Sbjct: 743 ERHKLIHTGVKSHACEQCGKSFARKDMLKEHMRVHDNVREYLCAECGKG 791


>gi|93204879 PR domain containing 15 isoform 1 [Homo sapiens]
          Length = 1507

 Score =  175 bits (444), Expect = 2e-43
 Identities = 187/745 (25%), Positives = 286/745 (38%), Gaps = 139/745 (18%)

Query: 114  VLTRARASLPLVLYIDRF---LGGVFSKRRIPKRTQFGPVEGPLVRGSELKDCYIHLKVS 170
            ++ + R+SLP  L I R      GVF+  ++ KRTQFGP E   V   E K+    LKV 
Sbjct: 405  LVAQGRSSLPPNLEIRRLEDGAEGVFAITQLVKRTQFGPFESRRVAKWE-KESAFPLKVF 463

Query: 171  LDKGDRKERDLHEDLWFELSDETLCNWMMFVRPAQNHLEQNLVAYQYGHHVYYTTIKNVE 230
                   ++D H  + F+ S+E  CNWMM VRPA     QNL AYQ+G  VY+TT +++ 
Sbjct: 464  -------QKDGHP-VCFDTSNEDDCNWMMLVRPAAEAEHQNLTAYQHGSDVYFTTSRDIP 515

Query: 231  PKQELKVWYAASYAEFVNQK--------IHDISEEERKVLREQE-KNWPCYECNRRFISS 281
            P  EL+VWYAA YA+ +++         +H     E     E E   W C  C+  F+  
Sbjct: 516  PGTELRVWYAAFYAKKMDKPMLKQAGSGVHAAGTPENSAPVESEPSQWACKVCSATFLEL 575

Query: 282  EQLQQHLNSHDEKL---------DVFSRTRGRGRGRGKRRFGPGR------------RPG 320
            + L +HL  H E+          +  +  + +   RG+    P              R G
Sbjct: 576  QLLNEHLLGHLEQAKSLPPGSQSEAAAPEKEQDTPRGEPPAVPESENVATKEQKKKPRRG 635

Query: 321  RPPKFIRLE---ITSENGEKSDDGTQDLLHFPTKEQFDEAEPATLNG--LDQPEQTTIPI 375
            R PK  + E   +  E+ E ++   + +   P  E         +    L +   TT   
Sbjct: 636  RKPKVSKAEQPLVIVEDKEPTEQVAEIITEVPPDEPVSATPDERIMELVLGKLATTTTDT 695

Query: 376  PQLPQETQSSLEHEPETHTL--------------HLQPQHEESVVPTQSTLTADDMRRAK 421
              +P+ T     H+  T TL               L  Q  E     Q  + +   + + 
Sbjct: 696  SSVPKFT----HHQNNTITLKRSLILSSRHGIRRKLIKQLGEHKRVYQCNICSKIFQNSS 751

Query: 422  RIRNAALQHLFIRKSFRPFKCLQCGKAFREKDKLDQHLRF-HGR---EGNCPLTCDLCNK 477
             +      H       + FKC +C K F  K+ L QH+ + H R   +G     C  C K
Sbjct: 752  NLSRHVRSH-----GDKLFKCEECAKLFSRKESLKQHVSYKHSRNEVDGEYRYRCGTCEK 806

Query: 478  GFISSTSLESHMKLHSDQKTYSCIFCPESFDRLDLLKDHVAIHINDGYFTCPTCKKRFPD 537
             F   ++LE H    +D KT+ C  C   F     L  H   H  D  F C  C K F  
Sbjct: 807  TFRIESALEFH-NCRTDDKTFQCEMCFRFFSTNSNLSKHKKKH-GDKKFACEVCSKMFYR 864

Query: 538  FIQVKKHVRSFHSEKIYQ----------------------CTECDKAFCRPDKLRLHMLR 575
               +  H R  H E + +                      C  C K F     +  H+L 
Sbjct: 865  KDVMLDHQRR-HLEGVRRVKREDLEAGGENLVRYKKEPSGCPVCGKVFSCRSNMNKHLLT 923

Query: 576  HSDRKDFLCSTCGKQFKRKDKLREHMQ-------RMHNPEREAKKAD-RISRSKTFKPRI 627
            H D+K + C  CG++F R D LR+H+         M + +RE       IS  +      
Sbjct: 924  HGDKK-YTCEICGRKFFRVDVLRDHIHVHFKDIALMDDHQREEFIGKIGISSEENDDNSD 982

Query: 628  TSTDYDSFTFKCRLCMMGFRRRGMLVNHLSKRHPDMKIEEVPELTLPIIKPNRDYFCQYC 687
             S D +   + C+ C + F R    + H+ + H +                 + Y C  C
Sbjct: 983  ESADSEPHKYSCKRCQLTFGRGKEYLKHIMEVHKE-----------------KGYGCSIC 1025

Query: 688  DKVYKSASKRKAHIL---KNHPGAELPPSIRKLRPAGP-----GEPDPMLSTHTQLTGTI 739
            ++ +   +   AH++   +N P   +   I      G      G  +     HT +    
Sbjct: 1026 NRRFALKATYHAHMVIHRENLPDPNVQKYIHPCEICGRIFNSIGNLERHKLIHTGVKSH- 1084

Query: 740  ATPPVCCPHCSKQYSSKTKMVQHIR 764
                  C  C K ++ K  + +H+R
Sbjct: 1085 -----ACEQCGKSFARKDMLKEHMR 1104



 Score =  116 bits (291), Expect = 9e-26
 Identities = 103/450 (22%), Positives = 166/450 (36%), Gaps = 118/450 (26%)

Query: 438  RPFKCLQCGKAFREKDKLDQHLRFH-------------------GREGNCPLTCDLCNKG 478
            + F C  C K F  KD +  H R H                    R    P  C +C K 
Sbjct: 851  KKFACEVCSKMFYRKDVMLDHQRRHLEGVRRVKREDLEAGGENLVRYKKEPSGCPVCGKV 910

Query: 479  FISSTSLESHMKLHSDQKTYSCIFCPESFDRLDLLKDHVAIHIND--------------- 523
            F   +++  H+  H D+K Y+C  C   F R+D+L+DH+ +H  D               
Sbjct: 911  FSCRSNMNKHLLTHGDKK-YTCEICGRKFFRVDVLRDHIHVHFKDIALMDDHQREEFIGK 969

Query: 524  --------------------GYFTCPTCKKRFPDFIQVKKHVRSFHSEKIYQCTECDKAF 563
                                  ++C  C+  F    +  KH+   H EK Y C+ C++ F
Sbjct: 970  IGISSEENDDNSDESADSEPHKYSCKRCQLTFGRGKEYLKHIMEVHKEKGYGCSICNRRF 1029

Query: 564  C---------------RPD---------------------KLRLHMLRHSDRKDFLCSTC 587
                             PD                      L  H L H+  K   C  C
Sbjct: 1030 ALKATYHAHMVIHRENLPDPNVQKYIHPCEICGRIFNSIGNLERHKLIHTGVKSHACEQC 1089

Query: 588  GKQFKRKDKLREHMQRMHNPERE--AKKADRISRSKTFKPRITSTDYDSFTFKCRLCMMG 645
            GK F RKD L+EHM R+H+  RE    +  +  ++K               ++C+ C   
Sbjct: 1090 GKSFARKDMLKEHM-RVHDNVREYLCAECGKGMKTKHALRHHMKLHKGIKEYECKECHRR 1148

Query: 646  FRRRGMLVNHLSKRHPDMKIEEVPELTLPIIKPNRDYFCQYCDKVYKSASKRKAHILKNH 705
            F ++  ++ H  KRH  +K                D+ C+ C K +   +  + H L + 
Sbjct: 1149 FAQKVNMLKH-CKRHTGIK----------------DFMCELCGKTFSERNTMETHKLIHT 1191

Query: 706  PGAELPPSIRKLRPAGPGEPDPMLSTHTQLTGTIATPPVCCPHCSKQYSSKTKMVQHIRK 765
             G +   S+   +       + ML  H QLT         C  C  + S++  M +H+R+
Sbjct: 1192 VGKQWTCSVCDKKYV----TEYMLQKHVQLTHD-KVEAQSCQLCGTKVSTRASMSRHMRR 1246

Query: 766  KHPEF--AQLSNTIHTPLTTAVISATPAVL 793
            KHPE    ++ +  H P TT + +++  ++
Sbjct: 1247 KHPEVLAVRIDDLDHLPETTTIDASSIGIV 1276



 Score =  110 bits (276), Expect = 5e-24
 Identities = 119/522 (22%), Positives = 202/522 (38%), Gaps = 74/522 (14%)

Query: 428  LQHLFIRKSFRPFKCLQCGKAFREKDKLDQHLRFHGREGNCPLT------CDLCNKGFIS 481
            L+H+      + + C  C + F  K     H+  H      P        C++C + F S
Sbjct: 1008 LKHIMEVHKEKGYGCSICNRRFALKATYHAHMVIHRENLPDPNVQKYIHPCEICGRIFNS 1067

Query: 482  STSLESHMKLHSDQKTYSCIFCPESFDRLDLLKDHVAIHINDGYFTCPTCKKRFPDFIQV 541
              +LE H  +H+  K+++C  C +SF R D+LK+H+ +H N   + C  C K       +
Sbjct: 1068 IGNLERHKLIHTGVKSHACEQCGKSFARKDMLKEHMRVHDNVREYLCAECGKGMKTKHAL 1127

Query: 542  KKHVRSFHSEKIYQCTECDKAFCRPDKLRLHMLRHSDRKDFLCSTCGKQFKRKDKLREHM 601
            + H++     K Y+C EC + F +   +  H  RH+  KDF+C  CGK F  ++ +  H 
Sbjct: 1128 RHHMKLHKGIKEYECKECHRRFAQKVNMLKHCKRHTGIKDFMCELCGKTFSERNTMETH- 1186

Query: 602  QRMHNPERE--AKKADRISRSKTFKPRITSTDYDSFTFK-CRLCMMGFRRRGMLVNHLSK 658
            + +H   ++      D+   ++    +     +D    + C+LC      R  +  H+ +
Sbjct: 1187 KLIHTVGKQWTCSVCDKKYVTEYMLQKHVQLTHDKVEAQSCQLCGTKVSTRASMSRHMRR 1246

Query: 659  RHPDM------KIEEVPELT------LPIIKPNRDYFCQYCDKVYKSASKRKAHILKNHP 706
            +HP++       ++ +PE T      + I++P      +   +     + +++H  K  P
Sbjct: 1247 KHPEVLAVRIDDLDHLPETTTIDASSIGIVQPELTLEQEDLAEGKHGKAAKRSHKRKQKP 1306

Query: 707  ----GAELPP-------SIRKLRPAGP--GEPDPMLSTHTQLTGTIATPPVCCPHCSKQY 753
                GA +P        S ++    G    E +  + +  Q+  T+  P V  P  S   
Sbjct: 1307 EEEAGAPVPEDATFSEYSEKETEFTGSVGDETNSAVQSIQQVVVTLGDPNVTTPSSS--- 1363

Query: 754  SSKTKMVQHIRKKHPEFAQLSNTIHTPLTTAVISATPAVLTTDSATGETVVTTDLLTQAM 813
                               L+N   TP+TTA  +AT        A G  + T +   Q  
Sbjct: 1364 -----------------VGLTNITVTPITTA--AATQFTNLQPVAVGH-LTTPERQLQLD 1403

Query: 814  TELSQTLTTDYRTPQG-----DYQRIQYIPVSQSASGLQQPQHIQLQVVQVASVS----- 863
              +   LT  + T  G     + Q    I     AS  Q   H       V S++     
Sbjct: 1404 NSI---LTVTFDTVSGSAMLHNRQNDVQIHPQPEASNPQSVAHFINLTTLVNSITPLGSQ 1460

Query: 864  ---GQPLSPSAQQAQQGLSPSHIQGSSSTQGQALQQQQQQQQ 902
                 PL+  A      L PS  Q       Q   Q +QQQQ
Sbjct: 1461 LSDQHPLTWRAVPQTDVLPPSQPQAPPQQAAQPQVQAEQQQQ 1502



 Score = 39.3 bits (90), Expect = 0.019
 Identities = 15/34 (44%), Positives = 24/34 (70%)

Query: 87  LWCEECNNAHASVCPKHGPLHPIPNRPVLTRARA 120
           +WCE+C+  H S CP+ GP+  + +  VL+RAR+
Sbjct: 312 IWCEDCSQYHDSECPELGPVVMVKDSFVLSRARS 345



 Score = 32.7 bits (73), Expect = 1.8
 Identities = 39/163 (23%), Positives = 63/163 (38%), Gaps = 33/163 (20%)

Query: 257  EERKVLREQEKNWPCYECNRRFISSEQLQQHLNSHDEKLDVFS----RTRGRGRGRGKRR 312
            E  K++    K W C  C++++++   LQ+H+    +K++  S     T+   R    R 
Sbjct: 1184 ETHKLIHTVGKQWTCSVCDKKYVTEYMLQKHVQLTHDKVEAQSCQLCGTKVSTRASMSRH 1243

Query: 313  FGPGRRPGRPPKFIRLEITSENGEKSDDGTQDLLHFPTKEQFDEAEPATLNGLDQPEQTT 372
                RR  + P+ + + I             DL H P     D    A+  G+ QPE T 
Sbjct: 1244 M---RR--KHPEVLAVRI------------DDLDHLPETTTID----ASSIGIVQPELT- 1281

Query: 373  IPIPQLPQETQSSLEHEPETHTLHLQPQ--HEESVVPTQSTLT 413
                 L QE  +  +H       H + Q   EE+  P     T
Sbjct: 1282 -----LEQEDLAEGKHGKAAKRSHKRKQKPEEEAGAPVPEDAT 1319



 Score = 31.6 bits (70), Expect = 4.0
 Identities = 12/49 (24%), Positives = 23/49 (46%)

Query: 257  EERKVLREQEKNWPCYECNRRFISSEQLQQHLNSHDEKLDVFSRTRGRG 305
            E  K++    K+  C +C + F   + L++H+  HD   +      G+G
Sbjct: 1072 ERHKLIHTGVKSHACEQCGKSFARKDMLKEHMRVHDNVREYLCAECGKG 1120


>gi|222831664 zinc finger protein 184 [Homo sapiens]
          Length = 751

 Score =  151 bits (381), Expect = 3e-36
 Identities = 135/521 (25%), Positives = 199/521 (38%), Gaps = 71/521 (13%)

Query: 266 EKNWPCYECNRRFISSEQLQQHLNSHDEKLDVFSRTRGRGRGRGK-----RRFGPGRRPG 320
           EK + C EC + F  SE L  H   H           G+G   G      +R   G +P 
Sbjct: 247 EKPYKCNECEKAFSRSENLINHQRIHTGDKPYKCDQCGKGFIEGPSLTQHQRIHTGEKPY 306

Query: 321 RPPKFIRLEITSENGEKSDDGTQDLLHFPTKEQFDEAEPATLNGLDQP--------EQTT 372
           +           E G+     T  + H   +      +P T N   +         E   
Sbjct: 307 K---------CDECGKAFSQRTHLVQH---QRIHTGEKPYTCNECGKAFSQRGHFMEHQK 354

Query: 373 IPIPQLPQETQSSLEHEPETHTLHLQPQHEESVVPTQSTLTADDMRRAKRIRNAALQHLF 432
           I   + P +       +  T + HL  QH++ +   + T   ++  +A    +  ++H  
Sbjct: 355 IHTGEKPFKCDEC--DKTFTRSTHLT-QHQK-IHTGEKTYKCNECGKAFNGPSTFIRHHM 410

Query: 433 IRKSFRPFKCLQCGKAFREKDKLDQHLRFHGREGNCPLTCDLCNKGFISSTSLESHMKLH 492
           I    +P++C +CGKAF +   L QH + H   G  P  C  C K F   +SL  H+K+H
Sbjct: 411 IHTGEKPYECNECGKAFSQHSNLTQHQKTH--TGEKPYDCAECGKSFSYWSSLAQHLKIH 468

Query: 493 SDQKTYSCIFCPESFDRLDLLKDHVAIHINDGYFTCPTCKKRFPDFIQVKKHVRSFHSEK 552
           + +K Y C  C ++F     L  H  IH  +  F C  C K F     + +H ++   EK
Sbjct: 469 TGEKPYKCNECGKAFSYCSSLTQHRRIHTREKPFECSECGKAFSYLSNLNQHQKTHTQEK 528

Query: 553 IYQCTECDKAFCRPDKLRLHMLRHSDRKDFLCSTCGKQFKRKDKLREHMQRMHNPEREAK 612
            Y+C EC KAF R   L  H   H+  K + C  CGK F     L +H +++H  ER  K
Sbjct: 529 AYECKECGKAFIRSSSLAKHERIHTGEKPYQCHECGKTFSYGSSLIQH-RKIHTGERPYK 587

Query: 613 KADRISRSKTFKPRITSTDYDSF-----TFKCRLCMMGFRRRGMLVNHLSKRHPDMKIEE 667
             +     + F   I  T +         ++C  C   FR    L  H  K H + K   
Sbjct: 588 CNE---CGRAFNQNIHLTQHKRIHTGAKPYECAECGKAFRHCSSLAQH-QKTHTEEK--- 640

Query: 668 VPELTLPIIKPNRDYFCQYCDKVYKSASKRKAHILKNHPGAELPPSIRKLRPAGPGEPDP 727
                         Y C  C+K +  +S    H  + H G          +P    E D 
Sbjct: 641 -------------PYQCNKCEKTFSQSSHLTQH-QRIHTGE---------KPYKCNECDK 677

Query: 728 MLSTHTQLTGTIAT----PPVCCPHCSKQYSSKTKMVQHIR 764
             S  T LT    T     P  C  C K +S  T ++QH R
Sbjct: 678 AFSRSTHLTEHQNTHTGEKPYNCNECRKTFSQSTYLIQHQR 718



 Score =  133 bits (334), Expect = 1e-30
 Identities = 103/396 (26%), Positives = 154/396 (38%), Gaps = 27/396 (6%)

Query: 387 EHEPETHTLHLQPQHEESVVPTQSTLTADDMRRAKRIRNAALQHLFIRKSFRPFKCLQCG 446
           E  PE  +     +   + V  + +   ++  +A    +A ++H       +P+KC +C 
Sbjct: 197 EPSPEETSTKRSIKQNSNPVKKEKSCKCNECGKAFSYCSALIRHQRTHTGEKPYKCNECE 256

Query: 447 KAFREKDKLDQHLRFHGREGNCPLTCDLCNKGFISSTSLESHMKLHSDQKTYSCIFCPES 506
           KAF   + L  H R H   G+ P  CD C KGFI   SL  H ++H+ +K Y C  C ++
Sbjct: 257 KAFSRSENLINHQRIH--TGDKPYKCDQCGKGFIEGPSLTQHQRIHTGEKPYKCDECGKA 314

Query: 507 FDRLDLLKDHVAIHINDGYFTCPTCKKRFPDFIQVKKHVRSFHSEKIYQCTECDKAFCRP 566
           F +   L  H  IH  +  +TC  C K F       +H +    EK ++C ECDK F R 
Sbjct: 315 FSQRTHLVQHQRIHTGEKPYTCNECGKAFSQRGHFMEHQKIHTGEKPFKCDECDKTFTRS 374

Query: 567 DKLRLHMLRHSDRKDFLCSTCGKQFKRKDK-LREHMQRMHNPEREAKKADRISRSKTFKP 625
             L  H   H+  K + C+ CGK F      +R HM        E  +  +     +   
Sbjct: 375 THLTQHQKIHTGEKTYKCNECGKAFNGPSTFIRHHMIHTGEKPYECNECGKAFSQHSNLT 434

Query: 626 RITSTDYDSFTFKCRLCMMGFRRRGMLVNHLSKRHPDMKIEEVPE----------LT--L 673
           +   T      + C  C   F     L  HL K H   K  +  E          LT   
Sbjct: 435 QHQKTHTGEKPYDCAECGKSFSYWSSLAQHL-KIHTGEKPYKCNECGKAFSYCSSLTQHR 493

Query: 674 PIIKPNRDYFCQYCDKVYKSASKRKAHILKNHPGAELPPSIRKLRPAGPG-EPDPMLSTH 732
            I    + + C  C K +   S      L  H          + +  G        L+ H
Sbjct: 494 RIHTREKPFECSECGKAFSYLSN-----LNQHQKTHTQEKAYECKECGKAFIRSSSLAKH 548

Query: 733 TQL-TGTIATPPVCCPHCSKQYSSKTKMVQHIRKKH 767
            ++ TG     P  C  C K +S  + ++QH RK H
Sbjct: 549 ERIHTG---EKPYQCHECGKTFSYGSSLIQH-RKIH 580



 Score =  127 bits (320), Expect = 4e-29
 Identities = 65/181 (35%), Positives = 90/181 (49%), Gaps = 3/181 (1%)

Query: 425 NAALQHLFIRKSFRPFKCLQCGKAFREKDKLDQHLRFHGREGNCPLTCDLCNKGFISSTS 484
           ++ +QH  I    RP+KC +CG+AF +   L QH R H   G  P  C  C K F   +S
Sbjct: 571 SSLIQHRKIHTGERPYKCNECGRAFNQNIHLTQHKRIH--TGAKPYECAECGKAFRHCSS 628

Query: 485 LESHMKLHSDQKTYSCIFCPESFDRLDLLKDHVAIHINDGYFTCPTCKKRFPDFIQVKKH 544
           L  H K H+++K Y C  C ++F +   L  H  IH  +  + C  C K F     + +H
Sbjct: 629 LAQHQKTHTEEKPYQCNKCEKTFSQSSHLTQHQRIHTGEKPYKCNECDKAFSRSTHLTEH 688

Query: 545 VRSFHSEKIYQCTECDKAFCRPDKLRLHMLRHSDRKDFLCSTCGKQFKRKDKLREHMQRM 604
             +   EK Y C EC K F +   L  H   HS  K F C+ CGK F+ +  L +H QR+
Sbjct: 689 QNTHTGEKPYNCNECRKTFSQSTYLIQHQRIHSGEKPFGCNDCGKSFRYRSALNKH-QRL 747

Query: 605 H 605
           H
Sbjct: 748 H 748


>gi|32698886 zinc finger protein 595 [Homo sapiens]
          Length = 648

 Score =  150 bits (378), Expect = 8e-36
 Identities = 108/350 (30%), Positives = 155/350 (44%), Gaps = 36/350 (10%)

Query: 419 RAKRIRNAALQHLFIRKSFRPFKCLQCGKAFREKDKLDQHLRFHGREGNCPLTCDLCNKG 478
           +A R   +  +H  I    +P+KC +CGKAFR+   L++H   H   G  P TC+ C K 
Sbjct: 291 KAFRWSTSLNEHKNIHTGEKPYKCKECGKAFRQSRSLNEHKNIH--TGEKPYTCEKCGKA 348

Query: 479 FISSTSLESHMKLHSDQKTYSCIFCPESFDRLDLLKDHVAIHINDGYFTCPTCKKRFPDF 538
           F  S+SL  H  +HS+QK Y C  C ++F     L  H  IH  +  +TC  C K F   
Sbjct: 349 FNQSSSLIIHRSIHSEQKLYKCEECGKAFTWSSSLNKHKRIHTGEKPYTCEECGKAFYRS 408

Query: 539 IQVKKHVRSFHSEKIYQCTECDKAFCRPDKLRLHMLRHSDRKDFLCSTCGKQFKRKDKLR 598
             + KH R    EK Y C EC KAF +   L LH   HS +K + C  CGK F R   L 
Sbjct: 409 SHLAKHKRIHTGEKPYTCEECGKAFNQSSTLILHKRIHSGQKPYKCEECGKAFTRSTTLN 468

Query: 599 EHMQRMHNPER-----EAKKADRISRSKTFKPRITSTDYDSFTFKCRLCMMGFRRRGMLV 653
           EH +++H  E+     E  KA   S S      I + +     +KC+ C   F +   L+
Sbjct: 469 EH-KKIHTGEKPYKCEECGKAFIWSASLNEHKNIHTGEK---PYKCKECGKAFNQSSGLI 524

Query: 654 NHLSKRHPDMKIEEVPELTLPIIKPNRDYFCQYCDKVYKSASKRKAHILKNHPGAELPPS 713
            H S  H + K+                Y C+ C K +  ++    H  K H G E P  
Sbjct: 525 IHRS-IHSEQKL----------------YKCEECGKAFTRSTALNEH-KKIHSG-EKPYK 565

Query: 714 IRKLRPAGPGEPDPMLSTHTQL-TGTIATPPVCCPHCSKQYSSKTKMVQH 762
            ++   A        L+ H ++ TG     P  C  C K ++  + + +H
Sbjct: 566 CKECGKA--YNLSSTLTKHKRIHTG---EKPFTCEECGKAFNWSSSLTKH 610



 Score =  141 bits (356), Expect = 3e-33
 Identities = 108/371 (29%), Positives = 151/371 (40%), Gaps = 34/371 (9%)

Query: 413 TADDMRRAKRIRNAALQHLFIRKSFRPFKCLQCGKAFREKDKLDQHLRFHGREGNCPLTC 472
           T ++  +A R      +H  I    +P+KC +CGKAF     L++H + H   G  P  C
Sbjct: 229 TCEECGKAFRRSTVLNEHKKIHTGEKPYKCEECGKAFTRSTTLNEHKKIH--TGEKPYKC 286

Query: 473 DLCNKGFISSTSLESHMKLHSDQKTYSCIFCPESFDRLDLLKDHVAIHINDGYFTCPTCK 532
             C K F  STSL  H  +H+ +K Y C  C ++F +   L +H  IH  +  +TC  C 
Sbjct: 287 KECGKAFRWSTSLNEHKNIHTGEKPYKCKECGKAFRQSRSLNEHKNIHTGEKPYTCEKCG 346

Query: 533 KRFPDFIQVKKHVRSFHSE-KIYQCTECDKAFCRPDKLRLHMLRHSDRKDFLCSTCGKQF 591
           K F     +  H RS HSE K+Y+C EC KAF     L  H   H+  K + C  CGK F
Sbjct: 347 KAFNQSSSLIIH-RSIHSEQKLYKCEECGKAFTWSSSLNKHKRIHTGEKPYTCEECGKAF 405

Query: 592 KRKDKLREHMQRMHNPER-----EAKKADRISRSKTFKPRITSTDYDSFTFKCRLCMMGF 646
            R   L +H +R+H  E+     E  KA   S +     RI S       +KC  C   F
Sbjct: 406 YRSSHLAKH-KRIHTGEKPYTCEECGKAFNQSSTLILHKRIHS---GQKPYKCEECGKAF 461

Query: 647 RRRGMLVNHLSKRHPDMKIEEVPELTLPII------------KPNRDYFCQYCDKVYKSA 694
            R   L  H  K H   K  +  E     I               + Y C+ C K +  +
Sbjct: 462 TRSTTLNEH-KKIHTGEKPYKCEECGKAFIWSASLNEHKNIHTGEKPYKCKECGKAFNQS 520

Query: 695 SKRKAHILKNHPGAELPPSIRKLRPAGPG-EPDPMLSTHTQLTGTIATPPVCCPHCSKQY 753
           S      L  H        + K    G        L+ H ++       P  C  C K Y
Sbjct: 521 SG-----LIIHRSIHSEQKLYKCEECGKAFTRSTALNEHKKIHS--GEKPYKCKECGKAY 573

Query: 754 SSKTKMVQHIR 764
           +  + + +H R
Sbjct: 574 NLSSTLTKHKR 584



 Score =  139 bits (350), Expect = 1e-32
 Identities = 124/469 (26%), Positives = 187/469 (39%), Gaps = 50/469 (10%)

Query: 255 SEEERKVLREQEKNWPCYECNRRFISSEQLQQHLNSHDEKLDVFSRTRGRGRGRGK---- 310
           S  + K +   EK + C EC + F  S  L +H   H  +        G+   R      
Sbjct: 214 SLSKHKRIHTGEKPYTCEECGKAFRRSTVLNEHKKIHTGEKPYKCEECGKAFTRSTTLNE 273

Query: 311 -RRFGPGRRPGRPP---KFIRLEITSENGEKSDDGTQDLLHFPTKE-QFDEAEPATLNGL 365
            ++   G +P +     K  R   TS N  K+       +H   K  +  E   A     
Sbjct: 274 HKKIHTGEKPYKCKECGKAFRWS-TSLNEHKN-------IHTGEKPYKCKECGKAFRQSR 325

Query: 366 DQPEQTTIPIPQLPQETQSSLEHEPETHTLHLQPQHEESVVPTQSTLTADDMRRAKRIRN 425
              E   I   + P   +   +   ++ +L +      S+   Q     ++  +A    +
Sbjct: 326 SLNEHKNIHTGEKPYTCEKCGKAFNQSSSLIIH----RSIHSEQKLYKCEECGKAFTWSS 381

Query: 426 AALQHLFIRKSFRPFKCLQCGKAFREKDKLDQHLRFHGREGNCPLTCDLCNKGFISSTSL 485
           +  +H  I    +P+ C +CGKAF     L +H R H   G  P TC+ C K F  S++L
Sbjct: 382 SLNKHKRIHTGEKPYTCEECGKAFYRSSHLAKHKRIH--TGEKPYTCEECGKAFNQSSTL 439

Query: 486 ESHMKLHSDQKTYSCIFCPESFDRLDLLKDHVAIHINDGYFTCPTCKKRFPDFIQVKKHV 545
             H ++HS QK Y C  C ++F R   L +H  IH  +  + C  C K F     + +H 
Sbjct: 440 ILHKRIHSGQKPYKCEECGKAFTRSTTLNEHKKIHTGEKPYKCEECGKAFIWSASLNEHK 499

Query: 546 RSFHSEKIYQCTECDKAFCRPDKLRLHMLRHSDRKDFLCSTCGKQFKRKDKLREHMQRMH 605
                EK Y+C EC KAF +   L +H   HS++K + C  CGK F R   L EH +++H
Sbjct: 500 NIHTGEKPYKCKECGKAFNQSSGLIIHRSIHSEQKLYKCEECGKAFTRSTALNEH-KKIH 558

Query: 606 NPE-----REAKKADRISRSKTFKPRITSTDYDSFTFKCRLCMMGFRRRGMLVNHLSKRH 660
           + E     +E  KA  +S + T   RI + +     F C  C   F     L  H     
Sbjct: 559 SGEKPYKCKECGKAYNLSSTLTKHKRIHTGEK---PFTCEECGKAFNWSSSLTKH----- 610

Query: 661 PDMKIEEVPELTLPIIKPNRDYFCQYCDKVYKSASKRKAHILKNHPGAE 709
              KI    E         + Y C+ C K +   S    H  + H G E
Sbjct: 611 ---KIIHTGE---------KSYKCEECGKAFNRPSTLTVH-KRIHTGKE 646



 Score =  134 bits (337), Expect = 4e-31
 Identities = 101/357 (28%), Positives = 144/357 (40%), Gaps = 29/357 (8%)

Query: 429 QHLFIRKSFRPFKCLQCGKAFREKDKLDQHLRFHGREGNCPLTCDLCNKGFISSTSLESH 488
           QH  I    +P+KC +CGKAF     L +H R H   G  P TC+ C K F  ST L  H
Sbjct: 189 QHTGIHAGEKPYKCEKCGKAFNRSTSLSKHKRIH--TGEKPYTCEECGKAFRRSTVLNEH 246

Query: 489 MKLHSDQKTYSCIFCPESFDRLDLLKDHVAIHINDGYFTCPTCKKRFPDFIQVKKHVRSF 548
            K+H+ +K Y C  C ++F R   L +H  IH  +  + C  C K F     + +H    
Sbjct: 247 KKIHTGEKPYKCEECGKAFTRSTTLNEHKKIHTGEKPYKCKECGKAFRWSTSLNEHKNIH 306

Query: 549 HSEKIYQCTECDKAFCRPDKLRLHMLRHSDRKDFLCSTCGKQFKRKDKLREHMQRMHNPE 608
             EK Y+C EC KAF +   L  H   H+  K + C  CGK F +   L  H  R  + E
Sbjct: 307 TGEKPYKCKECGKAFRQSRSLNEHKNIHTGEKPYTCEKCGKAFNQSSSLIIH--RSIHSE 364

Query: 609 REAKKADRISRSKTFKPRITS---TDYDSFTFKCRLCMMGFRRRGMLVNHLSKRHPDMKI 665
           ++  K +   ++ T+   +            + C  C   F R   L  H  + H   K 
Sbjct: 365 QKLYKCEECGKAFTWSSSLNKHKRIHTGEKPYTCEECGKAFYRSSHLAKH-KRIHTGEKP 423

Query: 666 EEVPE------------LTLPIIKPNRDYFCQYCDKVYKSASKRKAHILKNHPGAELPPS 713
               E            L   I    + Y C+ C K +  ++    H  K H G E P  
Sbjct: 424 YTCEECGKAFNQSSTLILHKRIHSGQKPYKCEECGKAFTRSTTLNEH-KKIHTG-EKPYK 481

Query: 714 IRKLRPAGPGEPDPMLSTHTQL-TGTIATPPVCCPHCSKQYSSKTKMVQHIRKKHPE 769
             +   A        L+ H  + TG     P  C  C K ++  + ++ H R  H E
Sbjct: 482 CEECGKAFIWSAS--LNEHKNIHTG---EKPYKCKECGKAFNQSSGLIIH-RSIHSE 532



 Score =  128 bits (321), Expect = 3e-29
 Identities = 95/330 (28%), Positives = 138/330 (41%), Gaps = 35/330 (10%)

Query: 438 RPFKCLQCGKAFREKDKLDQHLRFHGREGNCPLTCDLCNKGFISSTSLESHMKLHSDQKT 497
           +PFKC +CG++F     L QH   H   G  P  C+ C K F  STSL  H ++H+ +K 
Sbjct: 171 KPFKCTECGRSFY-MSHLTQHTGIHA--GEKPYKCEKCGKAFNRSTSLSKHKRIHTGEKP 227

Query: 498 YSCIFCPESFDRLDLLKDHVAIHINDGYFTCPTCKKRFPDFIQVKKHVRSFHSEKIYQCT 557
           Y+C  C ++F R  +L +H  IH  +  + C  C K F     + +H +    EK Y+C 
Sbjct: 228 YTCEECGKAFRRSTVLNEHKKIHTGEKPYKCEECGKAFTRSTTLNEHKKIHTGEKPYKCK 287

Query: 558 ECDKAFCRPDKLRLHMLRHSDRKDFLCSTCGKQFKRKDKLREHMQRMHNPER-----EAK 612
           EC KAF     L  H   H+  K + C  CGK F++   L EH + +H  E+     +  
Sbjct: 288 ECGKAFRWSTSLNEHKNIHTGEKPYKCKECGKAFRQSRSLNEH-KNIHTGEKPYTCEKCG 346

Query: 613 KADRISRSKTFKPRITSTDYDSFTFKCRLCMMGFRRRGMLVNHLSKRHPDMKIEEVPELT 672
           KA   S S      I S   +   +KC  C   F     L  H  KR             
Sbjct: 347 KAFNQSSSLIIHRSIHS---EQKLYKCEECGKAFTWSSSLNKH--KR------------- 388

Query: 673 LPIIKPNRDYFCQYCDKVYKSASKRKAHILKNHPGAELPPSIRKLRPAGPGEPDPMLSTH 732
             I    + Y C+ C K +  +S    H  + H G E P +  +   A        L  H
Sbjct: 389 --IHTGEKPYTCEECGKAFYRSSHLAKH-KRIHTG-EKPYTCEECGKA--FNQSSTLILH 442

Query: 733 TQLTGTIATPPVCCPHCSKQYSSKTKMVQH 762
            ++       P  C  C K ++  T + +H
Sbjct: 443 KRIHS--GQKPYKCEECGKAFTRSTTLNEH 470



 Score =  100 bits (249), Expect = 7e-21
 Identities = 78/297 (26%), Positives = 114/297 (38%), Gaps = 31/297 (10%)

Query: 472 CDLCNKGFISSTSLESHMKLHSDQKTYSCIFCPESFDRLDLLKDHVAIHINDGYFTCPTC 531
           C+ C K F   ++   H   H+ +K + C  C  SF  +  L  H  IH  +  + C  C
Sbjct: 147 CNTCVKVFSKFSNSNKHKIRHTGEKPFKCTECGRSF-YMSHLTQHTGIHAGEKPYKCEKC 205

Query: 532 KKRFPDFIQVKKHVRSFHSEKIYQCTECDKAFCRPDKLRLHMLRHSDRKDFLCSTCGKQF 591
            K F     + KH R    EK Y C EC KAF R   L  H   H+  K + C  CGK F
Sbjct: 206 GKAFNRSTSLSKHKRIHTGEKPYTCEECGKAFRRSTVLNEHKKIHTGEKPYKCEECGKAF 265

Query: 592 KRKDKLREHMQRMHNPER--EAKKADRISRSKTFKPRITSTDYDSFTFKCRLCMMGFRRR 649
            R   L EH +++H  E+  + K+  +  R  T      +       +KC+ C   FR+ 
Sbjct: 266 TRSTTLNEH-KKIHTGEKPYKCKECGKAFRWSTSLNEHKNIHTGEKPYKCKECGKAFRQS 324

Query: 650 GMLVNHLSKRHPDMKIEEVPELTLPIIKPNRDYFCQYCDKVYKSASKRKAHILKNHPGAE 709
             L       H ++   E P            Y C+ C K +  +S      L  H    
Sbjct: 325 RSL-----NEHKNIHTGEKP------------YTCEKCGKAFNQSSS-----LIIHRSIH 362

Query: 710 LPPSIRKLRPAGPGEP-DPMLSTHTQL-TGTIATPPVCCPHCSKQYSSKTKMVQHIR 764
               + K    G        L+ H ++ TG     P  C  C K +   + + +H R
Sbjct: 363 SEQKLYKCEECGKAFTWSSSLNKHKRIHTG---EKPYTCEECGKAFYRSSHLAKHKR 416



 Score = 74.3 bits (181), Expect = 5e-13
 Identities = 58/229 (25%), Positives = 87/229 (37%), Gaps = 29/229 (12%)

Query: 493 SDQKTYSCIFCPESFDRLDLLKDHVAIHINDGYFTCPTCKKRFPDFIQVKKHVRSFHSEK 552
           +  K + C  C + F +      H   H  +  F C  C + F     + +H      EK
Sbjct: 140 TQSKIFQCNTCVKVFSKFSNSNKHKIRHTGEKPFKCTECGRSF-YMSHLTQHTGIHAGEK 198

Query: 553 IYQCTECDKAFCRPDKLRLHMLRHSDRKDFLCSTCGKQFKRKDKLREHMQRMHNPEREAK 612
            Y+C +C KAF R   L  H   H+  K + C  CGK F+R   L EH +++H  E+  K
Sbjct: 199 PYKCEKCGKAFNRSTSLSKHKRIHTGEKPYTCEECGKAFRRSTVLNEH-KKIHTGEKPYK 257

Query: 613 KADRISRSKTFKPRITSTDYDSF-----TFKCRLCMMGFRRRGMLVNHLSKRHPDMKIEE 667
             +     K F    T  ++         +KC+ C   FR    L       H ++   E
Sbjct: 258 CEE---CGKAFTRSTTLNEHKKIHTGEKPYKCKECGKAFRWSTSL-----NEHKNIHTGE 309

Query: 668 VPELTLPIIKPNRDYFCQYCDKVYKSASKRKAHILKNHPGAELPPSIRK 716
            P            Y C+ C K ++ +     H  KN    E P +  K
Sbjct: 310 KP------------YKCKECGKAFRQSRSLNEH--KNIHTGEKPYTCEK 344



 Score = 70.9 bits (172), Expect = 6e-12
 Identities = 65/247 (26%), Positives = 93/247 (37%), Gaps = 30/247 (12%)

Query: 526 FTCPTCKKRFPDFIQVKKHVRSFHSEKIYQCTECDKAFCRPDKLRLHMLRHSDRKDFLCS 585
           F C TC K F  F    KH      EK ++CTEC ++F     L  H   H+  K + C 
Sbjct: 145 FQCNTCVKVFSKFSNSNKHKIRHTGEKPFKCTECGRSFYM-SHLTQHTGIHAGEKPYKCE 203

Query: 586 TCGKQFKRKDKLREHMQRMHNPER--EAKKADRISRSKTFKPRITSTDYDSFTFKCRLCM 643
            CGK F R   L +H +R+H  E+    ++  +  R  T              +KC  C 
Sbjct: 204 KCGKAFNRSTSLSKH-KRIHTGEKPYTCEECGKAFRRSTVLNEHKKIHTGEKPYKCEECG 262

Query: 644 MGFRRRGMLVNHLSKRHPDMKIEEVPELTLPIIKPNRDYFCQYCDKVYKSASKRKAHILK 703
             F R   L  H  K H   K                 Y C+ C K ++ ++    H  K
Sbjct: 263 KAFTRSTTLNEH-KKIHTGEK----------------PYKCKECGKAFRWSTSLNEH--K 303

Query: 704 NHPGAELPPSIRKLRPAGPGEPDPMLSTHTQL-TGTIATPPVCCPHCSKQYSSKTKMVQH 762
           N    E P   ++   A        L+ H  + TG     P  C  C K ++  + ++ H
Sbjct: 304 NIHTGEKPYKCKECGKA--FRQSRSLNEHKNIHTG---EKPYTCEKCGKAFNQSSSLIIH 358

Query: 763 IRKKHPE 769
            R  H E
Sbjct: 359 -RSIHSE 364



 Score = 32.7 bits (73), Expect = 1.8
 Identities = 45/193 (23%), Positives = 65/193 (33%), Gaps = 31/193 (16%)

Query: 574 LRHSDRKDFLCSTCGKQFKRKDKLREHMQRMHNPEREAKKADRISRS--KTFKPRITSTD 631
           L  +  K F C+TC K F +     +H  R H  E+   K     RS   +   + T   
Sbjct: 137 LSTTQSKIFQCNTCVKVFSKFSNSNKHKIR-HTGEKPF-KCTECGRSFYMSHLTQHTGIH 194

Query: 632 YDSFTFKCRLCMMGFRRRGMLVNHLSKRHPDMKIEEVPELTLPIIKPNRDYFCQYCDKVY 691
                +KC  C   F R   L  H  KR               I    + Y C+ C K +
Sbjct: 195 AGEKPYKCEKCGKAFNRSTSLSKH--KR---------------IHTGEKPYTCEECGKAF 237

Query: 692 KSASKRKAHILKNHPGAELPPSIRKLRPAGPG-EPDPMLSTHTQL-TGTIATPPVCCPHC 749
                R++ +L  H          K    G        L+ H ++ TG     P  C  C
Sbjct: 238 -----RRSTVLNEHKKIHTGEKPYKCEECGKAFTRSTTLNEHKKIHTG---EKPYKCKEC 289

Query: 750 SKQYSSKTKMVQH 762
            K +   T + +H
Sbjct: 290 GKAFRWSTSLNEH 302


>gi|239747149 PREDICTED: hypothetical protein XP_002343926 isoform 2
           [Homo sapiens]
          Length = 738

 Score =  149 bits (377), Expect = 1e-35
 Identities = 104/370 (28%), Positives = 153/370 (41%), Gaps = 38/370 (10%)

Query: 416 DMRRAKRIRNAALQHLFIRKSFRPFKCLQCGKAFREKDKLDQHLRFHGREGNCPLTCDLC 475
           D R+A   ++  ++H  I    +P++C +C KAFRE+  L  H R H   G  P  C  C
Sbjct: 379 DCRKAFFEKSELIRHQTIHTGEKPYECSECRKAFRERSSLINHQRTH--TGEKPHGCIQC 436

Query: 476 NKGFISSTSLESHMKLHSDQKTYSCIFCPESFDRLDLLKDHVAIHINDGYFTCPTCKKRF 535
            K F   + L SH   H+ +K + C  C ++F R   L  H   H  +  + C  C K F
Sbjct: 437 GKAFSQKSHLISHQMTHTGEKPFICSKCGKAFSRKSQLVRHQRTHTGEKPYECSECGKAF 496

Query: 536 PDFIQVKKHVRSFHSEKIYQCTECDKAFCRPDKLRLHMLRHSDRKDFLCSTCGKQFKRKD 595
            + + +  H R    EK Y C+EC KAFC+   L  H   H+  K + CS CGK F  K 
Sbjct: 497 SEKLSLTNHQRIHTGEKPYVCSECGKAFCQKSHLISHQRTHTGEKPYECSECGKAFGEKS 556

Query: 596 KLREHMQRMHNPER--EAKKADRISRSKTFKPRITSTDYDSFTFKCRLCMMGFRRRGMLV 653
            L  H QR H  E+  E +  ++    K+              ++C LC   F  +  L+
Sbjct: 557 SLATH-QRTHTGEKPYECRDCEKAFSQKSQLNTHQRIHTGEKPYECSLCRKAFFEKSELI 615

Query: 654 NHLSKRHPDMKIEEVPELTLP------------IIKPNRDYFCQYCDKVYKSASKRKAHI 701
            HL + H   K  E  E                I    + + C  C K +     RK+H+
Sbjct: 616 RHL-RTHTGEKPYECNECRKAFREKSSLINHQRIHTGEKPFECSECGKAF----SRKSHL 670

Query: 702 L---KNHPGAELPPSIRKLRPAGPGEPDPMLSTHTQLTG----TIATPPVCCPHCSKQYS 754
           +   + H G          +P G  E     S  +QL           P  C  C K +S
Sbjct: 671 IPHQRTHTGE---------KPYGCSECRKAFSQKSQLVNHQRIHTGEKPYRCIECGKAFS 721

Query: 755 SKTKMVQHIR 764
            K++++ H R
Sbjct: 722 QKSQLINHQR 731



 Score =  141 bits (355), Expect = 4e-33
 Identities = 95/333 (28%), Positives = 146/333 (43%), Gaps = 36/333 (10%)

Query: 438 RPFKCLQCGKAFREKDKLDQHLRFHGREGNCPLTCDLCNKGFISSTSLESHMKLHSDQKT 497
           +P+ C +CG+AF EK  L  H R H   G  P  C  C K F   + L +H + H+  K 
Sbjct: 317 KPYGCNECGRAFSEKSNLINHQRIH--TGEKPFECRECGKAFSRKSQLVTHHRTHTGTKP 374

Query: 498 YSCIFCPESFDRLDLLKDHVAIHINDGYFTCPTCKKRFPDFIQVKKHVRSFHSEKIYQCT 557
           + C  C ++F     L  H  IH  +  + C  C+K F +   +  H R+   EK + C 
Sbjct: 375 FGCSDCRKAFFEKSELIRHQTIHTGEKPYECSECRKAFRERSSLINHQRTHTGEKPHGCI 434

Query: 558 ECDKAFCRPDKLRLHMLRHSDRKDFLCSTCGKQFKRKDKLREHMQRMHNPEREAKKADRI 617
           +C KAF +   L  H + H+  K F+CS CGK F RK +L  H QR H  E+  + ++  
Sbjct: 435 QCGKAFSQKSHLISHQMTHTGEKPFICSKCGKAFSRKSQLVRH-QRTHTGEKPYECSE-- 491

Query: 618 SRSKTFKPRITSTDYDSF-----TFKCRLCMMGFRRRGMLVNHLSKRHPDMKIEEVPELT 672
              K F  +++ T++         + C  C   F ++  L++H  + H   K        
Sbjct: 492 -CGKAFSEKLSLTNHQRIHTGEKPYVCSECGKAFCQKSHLISH-QRTHTGEK-------- 541

Query: 673 LPIIKPNRDYFCQYCDKVYKSASKRKAHILKNHPGAELPPSIRKLRPAGPGEPDPMLSTH 732
                    Y C  C K +   S    H  + H G E P   R    A        L+TH
Sbjct: 542 --------PYECSECGKAFGEKSSLATH-QRTHTG-EKPYECRDCEKA--FSQKSQLNTH 589

Query: 733 TQL-TGTIATPPVCCPHCSKQYSSKTKMVQHIR 764
            ++ TG     P  C  C K +  K+++++H+R
Sbjct: 590 QRIHTG---EKPYECSLCRKAFFEKSELIRHLR 619



 Score =  140 bits (354), Expect = 5e-33
 Identities = 98/329 (29%), Positives = 140/329 (42%), Gaps = 28/329 (8%)

Query: 438 RPFKCLQCGKAFREKDKLDQHLRFHGREGNCPLTCDLCNKGFISSTSLESHMKLHSDQKT 497
           +PF C  C KAF EK +L +H   H   G  P  C  C K F   +SL +H + H+ +K 
Sbjct: 373 KPFGCSDCRKAFFEKSELIRHQTIH--TGEKPYECSECRKAFRERSSLINHQRTHTGEKP 430

Query: 498 YSCIFCPESFDRLDLLKDHVAIHINDGYFTCPTCKKRFPDFIQVKKHVRSFHSEKIYQCT 557
           + CI C ++F +   L  H   H  +  F C  C K F    Q+ +H R+   EK Y+C+
Sbjct: 431 HGCIQCGKAFSQKSHLISHQMTHTGEKPFICSKCGKAFSRKSQLVRHQRTHTGEKPYECS 490

Query: 558 ECDKAFCRPDKLRLHMLRHSDRKDFLCSTCGKQFKRKDKLREHMQRMHNPER--EAKKAD 615
           EC KAF     L  H   H+  K ++CS CGK F +K  L  H QR H  E+  E  +  
Sbjct: 491 ECGKAFSEKLSLTNHQRIHTGEKPYVCSECGKAFCQKSHLISH-QRTHTGEKPYECSECG 549

Query: 616 RISRSKTFKPRITSTDYDSFTFKCRLCMMGFRRRGMLVNHLSKRHPDMKIEEVPELTLPI 675
           +    K+       T      ++CR C   F ++  L  H                   I
Sbjct: 550 KAFGEKSSLATHQRTHTGEKPYECRDCEKAFSQKSQLNTHQR-----------------I 592

Query: 676 IKPNRDYFCQYCDKVYKSASKRKAHILKNHPGAELPPSIRKLRPAGPGEPDPMLSTHTQL 735
               + Y C  C K +   S+   H L+ H G E P    + R A   E   +++     
Sbjct: 593 HTGEKPYECSLCRKAFFEKSELIRH-LRTHTG-EKPYECNECRKAF-REKSSLINHQRIH 649

Query: 736 TGTIATPPVCCPHCSKQYSSKTKMVQHIR 764
           TG     P  C  C K +S K+ ++ H R
Sbjct: 650 TG---EKPFECSECGKAFSRKSHLIPHQR 675



 Score =  133 bits (335), Expect = 7e-31
 Identities = 108/344 (31%), Positives = 147/344 (42%), Gaps = 30/344 (8%)

Query: 438 RPFKCLQCGKAFREKDKLDQHLRFHGREGNCPLTCDLCNKGFISSTSLESHMKLHSDQKT 497
           +P+ C QCGKAF +K +L  H R H   G  P  C  C K F   + L SH + H+ +K 
Sbjct: 261 KPYNCSQCGKAFSQKSQLTSHQRTH--TGEKPYECGECGKAFSRKSHLISHWRTHTGEKP 318

Query: 498 YSCIFCPESFDRLDLLKDHVAIHINDGYFTCPTCKKRFPDFIQVKKHVRSFHSEKIYQCT 557
           Y C  C  +F     L +H  IH  +  F C  C K F    Q+  H R+    K + C+
Sbjct: 319 YGCNECGRAFSEKSNLINHQRIHTGEKPFECRECGKAFSRKSQLVTHHRTHTGTKPFGCS 378

Query: 558 ECDKAFCRPDKLRLHMLRHSDRKDFLCSTCGKQFKRKDKLREHMQRMHNPER-----EAK 612
           +C KAF    +L  H   H+  K + CS C K F+ +  L  H QR H  E+     +  
Sbjct: 379 DCRKAFFEKSELIRHQTIHTGEKPYECSECRKAFRERSSLINH-QRTHTGEKPHGCIQCG 437

Query: 613 KADRISRSKTFKPRITSTDYDSFTFKCRLCMMGFRRRGMLVNHLSKRHPDMKIEEVPE-- 670
           KA    +S     ++T T    F   C  C   F R+  LV H  + H   K  E  E  
Sbjct: 438 KAFS-QKSHLISHQMTHTGEKPFI--CSKCGKAFSRKSQLVRH-QRTHTGEKPYECSECG 493

Query: 671 ------LTLP----IIKPNRDYFCQYCDKVYKSASKRKAHILKNHPGAELPPSIRKLRPA 720
                 L+L     I    + Y C  C K +   S   +H  + H G E P    +   A
Sbjct: 494 KAFSEKLSLTNHQRIHTGEKPYVCSECGKAFCQKSHLISH-QRTHTG-EKPYECSECGKA 551

Query: 721 GPGEPDPMLSTHTQLTGTIATPPVCCPHCSKQYSSKTKMVQHIR 764
             GE    L+TH Q T T    P  C  C K +S K+++  H R
Sbjct: 552 F-GEKS-SLATH-QRTHT-GEKPYECRDCEKAFSQKSQLNTHQR 591



 Score =  124 bits (312), Expect = 3e-28
 Identities = 95/330 (28%), Positives = 135/330 (40%), Gaps = 34/330 (10%)

Query: 440 FKCLQCGKAFREKDKLDQHLRFHGREGNCPLTCDLCNKGFISSTSLESHMKLHSDQKTYS 499
           F C  CGK F +K +   H R H   G  P  C  C K F   + L SH + H+ +K Y 
Sbjct: 235 FGCGNCGKTFPQKSQFITHHRTH--TGEKPYNCSQCGKAFSQKSQLTSHQRTHTGEKPYE 292

Query: 500 CIFCPESFDRLDLLKDHVAIHINDGYFTCPTCKKRFPDFIQVKKHVRSFHSEKIYQCTEC 559
           C  C ++F R   L  H   H  +  + C  C + F +   +  H R    EK ++C EC
Sbjct: 293 CGECGKAFSRKSHLISHWRTHTGEKPYGCNECGRAFSEKSNLINHQRIHTGEKPFECREC 352

Query: 560 DKAFCRPDKLRLHMLRHSDRKDFLCSTCGKQFKRKDKLREHMQRMHNPER-----EAKKA 614
            KAF R  +L  H   H+  K F CS C K F  K +L  H Q +H  E+     E +KA
Sbjct: 353 GKAFSRKSQLVTHHRTHTGTKPFGCSDCRKAFFEKSELIRH-QTIHTGEKPYECSECRKA 411

Query: 615 DRISRSKTFKPRITSTDYDSFTFKCRLCMMGFRRRGMLVNHLSKRHPDMKIEEVPELTLP 674
            R  RS     + T T        C  C   F ++  L++H              ++T  
Sbjct: 412 FR-ERSSLINHQRTHT--GEKPHGCIQCGKAFSQKSHLISH--------------QMTHT 454

Query: 675 IIKPNRDYFCQYCDKVYKSASKRKAHILKNHPGAELPPSIRKLRPAGPGEPDPMLSTHTQ 734
             KP   + C  C K +   S+   H  + H G E P    +    G    + +  T+ Q
Sbjct: 455 GEKP---FICSKCGKAFSRKSQLVRH-QRTHTG-EKP---YECSECGKAFSEKLSLTNHQ 506

Query: 735 LTGTIATPPVCCPHCSKQYSSKTKMVQHIR 764
              T    P  C  C K +  K+ ++ H R
Sbjct: 507 RIHT-GEKPYVCSECGKAFCQKSHLISHQR 535



 Score =  120 bits (302), Expect = 5e-27
 Identities = 61/172 (35%), Positives = 87/172 (50%), Gaps = 3/172 (1%)

Query: 438 RPFKCLQCGKAFREKDKLDQHLRFHGREGNCPLTCDLCNKGFISSTSLESHMKLHSDQKT 497
           +P++C  C KAF +K +L+ H R H   G  P  C LC K F   + L  H++ H+ +K 
Sbjct: 569 KPYECRDCEKAFSQKSQLNTHQRIH--TGEKPYECSLCRKAFFEKSELIRHLRTHTGEKP 626

Query: 498 YSCIFCPESFDRLDLLKDHVAIHINDGYFTCPTCKKRFPDFIQVKKHVRSFHSEKIYQCT 557
           Y C  C ++F     L +H  IH  +  F C  C K F     +  H R+   EK Y C+
Sbjct: 627 YECNECRKAFREKSSLINHQRIHTGEKPFECSECGKAFSRKSHLIPHQRTHTGEKPYGCS 686

Query: 558 ECDKAFCRPDKLRLHMLRHSDRKDFLCSTCGKQFKRKDKLREHMQRMHNPER 609
           EC KAF +  +L  H   H+  K + C  CGK F +K +L  H QR H  ++
Sbjct: 687 ECRKAFSQKSQLVNHQRIHTGEKPYRCIECGKAFSQKSQLINH-QRTHTVKK 737



 Score =  108 bits (270), Expect = 3e-23
 Identities = 88/327 (26%), Positives = 126/327 (38%), Gaps = 28/327 (8%)

Query: 441 KCLQCGKAFREKDKLDQHLRFH-GREGNCPLTCDLCNKGFISSTSLESHMKLHSDQKTYS 499
           K   C K ++E  K  Q + +H  R G     C  C K F    SL  H   H     + 
Sbjct: 178 KYYDCDK-YKESYKKSQIIIYHRNRLGEKLYECSECRKRFSKKPSLIKHQSRHIRDIAFG 236

Query: 500 CIFCPESFDRLDLLKDHVAIHINDGYFTCPTCKKRFPDFIQVKKHVRSFHSEKIYQCTEC 559
           C  C ++F +      H   H  +  + C  C K F    Q+  H R+   EK Y+C EC
Sbjct: 237 CGNCGKTFPQKSQFITHHRTHTGEKPYNCSQCGKAFSQKSQLTSHQRTHTGEKPYECGEC 296

Query: 560 DKAFCRPDKLRLHMLRHSDRKDFLCSTCGKQFKRKDKLREHMQRMHNPER--EAKKADRI 617
            KAF R   L  H   H+  K + C+ CG+ F  K  L  H QR+H  E+  E ++  + 
Sbjct: 297 GKAFSRKSHLISHWRTHTGEKPYGCNECGRAFSEKSNLINH-QRIHTGEKPFECRECGKA 355

Query: 618 SRSKTFKPRITSTDYDSFTFKCRLCMMGFRRRGMLVNHLSKRHPDMKIEEVPELTLPIIK 677
              K+       T   +  F C  C   F  +  L+     RH  +   E P        
Sbjct: 356 FSRKSQLVTHHRTHTGTKPFGCSDCRKAFFEKSELI-----RHQTIHTGEKP-------- 402

Query: 678 PNRDYFCQYCDKVYKSASKRKAHILKNHPGAELPPSIRKLRPAGPGEPDPMLSTHTQLTG 737
               Y C  C K ++  S    H  + H G +    I+     G            Q+T 
Sbjct: 403 ----YECSECRKAFRERSSLINH-QRTHTGEKPHGCIQ----CGKAFSQKSHLISHQMTH 453

Query: 738 TIATPPVCCPHCSKQYSSKTKMVQHIR 764
           T    P  C  C K +S K+++V+H R
Sbjct: 454 T-GEKPFICSKCGKAFSRKSQLVRHQR 479



 Score = 78.2 bits (191), Expect = 4e-14
 Identities = 69/290 (23%), Positives = 105/290 (36%), Gaps = 30/290 (10%)

Query: 246 FVNQKIHDISEEERKVLREQ-----EKNWPCYECNRRFISSEQLQQHLNSHDEKLDVFSR 300
           F+  K       + +++R Q     EK + C EC + F     L  H   H  +      
Sbjct: 459 FICSKCGKAFSRKSQLVRHQRTHTGEKPYECSECGKAFSEKLSLTNHQRIHTGEKPYVCS 518

Query: 301 TRGRGRGRGKRRFGPGRRPGRPPKFIRLEITSENGEKSDDGTQDLLHFPTKE-QFDEAEP 359
             G+   +        R       +   E     GEKS   T    H   K  +  + E 
Sbjct: 519 ECGKAFCQKSHLISHQRTHTGEKPYECSECGKAFGEKSSLATHQRTHTGEKPYECRDCEK 578

Query: 360 ATLNGLDQPEQTTIPIPQLPQET---------QSSLEHEPETHTLHLQPQHEESVVPTQS 410
           A            I   + P E          +S L     THT              + 
Sbjct: 579 AFSQKSQLNTHQRIHTGEKPYECSLCRKAFFEKSELIRHLRTHT-------------GEK 625

Query: 411 TLTADDMRRAKRIRNAALQHLFIRKSFRPFKCLQCGKAFREKDKLDQHLRFHGREGNCPL 470
               ++ R+A R +++ + H  I    +PF+C +CGKAF  K  L  H R H   G  P 
Sbjct: 626 PYECNECRKAFREKSSLINHQRIHTGEKPFECSECGKAFSRKSHLIPHQRTH--TGEKPY 683

Query: 471 TCDLCNKGFISSTSLESHMKLHSDQKTYSCIFCPESFDRLDLLKDHVAIH 520
            C  C K F   + L +H ++H+ +K Y CI C ++F +   L +H   H
Sbjct: 684 GCSECRKAFSQKSQLVNHQRIHTGEKPYRCIECGKAFSQKSQLINHQRTH 733


>gi|239747147 PREDICTED: hypothetical protein XP_002343925 isoform 1
           [Homo sapiens]
          Length = 738

 Score =  149 bits (377), Expect = 1e-35
 Identities = 104/370 (28%), Positives = 153/370 (41%), Gaps = 38/370 (10%)

Query: 416 DMRRAKRIRNAALQHLFIRKSFRPFKCLQCGKAFREKDKLDQHLRFHGREGNCPLTCDLC 475
           D R+A   ++  ++H  I    +P++C +C KAFRE+  L  H R H   G  P  C  C
Sbjct: 379 DCRKAFFEKSELIRHQTIHTGEKPYECSECRKAFRERSSLINHQRTH--TGEKPHGCIQC 436

Query: 476 NKGFISSTSLESHMKLHSDQKTYSCIFCPESFDRLDLLKDHVAIHINDGYFTCPTCKKRF 535
            K F   + L SH   H+ +K + C  C ++F R   L  H   H  +  + C  C K F
Sbjct: 437 GKAFSQKSHLISHQMTHTGEKPFICSKCGKAFSRKSQLVRHQRTHTGEKPYECSECGKAF 496

Query: 536 PDFIQVKKHVRSFHSEKIYQCTECDKAFCRPDKLRLHMLRHSDRKDFLCSTCGKQFKRKD 595
            + + +  H R    EK Y C+EC KAFC+   L  H   H+  K + CS CGK F  K 
Sbjct: 497 SEKLSLTNHQRIHTGEKPYVCSECGKAFCQKSHLISHQRTHTGEKPYECSECGKAFGEKS 556

Query: 596 KLREHMQRMHNPER--EAKKADRISRSKTFKPRITSTDYDSFTFKCRLCMMGFRRRGMLV 653
            L  H QR H  E+  E +  ++    K+              ++C LC   F  +  L+
Sbjct: 557 SLATH-QRTHTGEKPYECRDCEKAFSQKSQLNTHQRIHTGEKPYECSLCRKAFFEKSELI 615

Query: 654 NHLSKRHPDMKIEEVPELTLP------------IIKPNRDYFCQYCDKVYKSASKRKAHI 701
            HL + H   K  E  E                I    + + C  C K +     RK+H+
Sbjct: 616 RHL-RTHTGEKPYECNECRKAFREKSSLINHQRIHTGEKPFECSECGKAF----SRKSHL 670

Query: 702 L---KNHPGAELPPSIRKLRPAGPGEPDPMLSTHTQLTG----TIATPPVCCPHCSKQYS 754
           +   + H G          +P G  E     S  +QL           P  C  C K +S
Sbjct: 671 IPHQRTHTGE---------KPYGCSECRKAFSQKSQLVNHQRIHTGEKPYRCIECGKAFS 721

Query: 755 SKTKMVQHIR 764
            K++++ H R
Sbjct: 722 QKSQLINHQR 731



 Score =  141 bits (355), Expect = 4e-33
 Identities = 95/333 (28%), Positives = 146/333 (43%), Gaps = 36/333 (10%)

Query: 438 RPFKCLQCGKAFREKDKLDQHLRFHGREGNCPLTCDLCNKGFISSTSLESHMKLHSDQKT 497
           +P+ C +CG+AF EK  L  H R H   G  P  C  C K F   + L +H + H+  K 
Sbjct: 317 KPYGCNECGRAFSEKSNLINHQRIH--TGEKPFECRECGKAFSRKSQLVTHHRTHTGTKP 374

Query: 498 YSCIFCPESFDRLDLLKDHVAIHINDGYFTCPTCKKRFPDFIQVKKHVRSFHSEKIYQCT 557
           + C  C ++F     L  H  IH  +  + C  C+K F +   +  H R+   EK + C 
Sbjct: 375 FGCSDCRKAFFEKSELIRHQTIHTGEKPYECSECRKAFRERSSLINHQRTHTGEKPHGCI 434

Query: 558 ECDKAFCRPDKLRLHMLRHSDRKDFLCSTCGKQFKRKDKLREHMQRMHNPEREAKKADRI 617
           +C KAF +   L  H + H+  K F+CS CGK F RK +L  H QR H  E+  + ++  
Sbjct: 435 QCGKAFSQKSHLISHQMTHTGEKPFICSKCGKAFSRKSQLVRH-QRTHTGEKPYECSE-- 491

Query: 618 SRSKTFKPRITSTDYDSF-----TFKCRLCMMGFRRRGMLVNHLSKRHPDMKIEEVPELT 672
              K F  +++ T++         + C  C   F ++  L++H  + H   K        
Sbjct: 492 -CGKAFSEKLSLTNHQRIHTGEKPYVCSECGKAFCQKSHLISH-QRTHTGEK-------- 541

Query: 673 LPIIKPNRDYFCQYCDKVYKSASKRKAHILKNHPGAELPPSIRKLRPAGPGEPDPMLSTH 732
                    Y C  C K +   S    H  + H G E P   R    A        L+TH
Sbjct: 542 --------PYECSECGKAFGEKSSLATH-QRTHTG-EKPYECRDCEKA--FSQKSQLNTH 589

Query: 733 TQL-TGTIATPPVCCPHCSKQYSSKTKMVQHIR 764
            ++ TG     P  C  C K +  K+++++H+R
Sbjct: 590 QRIHTG---EKPYECSLCRKAFFEKSELIRHLR 619



 Score =  140 bits (354), Expect = 5e-33
 Identities = 98/329 (29%), Positives = 140/329 (42%), Gaps = 28/329 (8%)

Query: 438 RPFKCLQCGKAFREKDKLDQHLRFHGREGNCPLTCDLCNKGFISSTSLESHMKLHSDQKT 497
           +PF C  C KAF EK +L +H   H   G  P  C  C K F   +SL +H + H+ +K 
Sbjct: 373 KPFGCSDCRKAFFEKSELIRHQTIH--TGEKPYECSECRKAFRERSSLINHQRTHTGEKP 430

Query: 498 YSCIFCPESFDRLDLLKDHVAIHINDGYFTCPTCKKRFPDFIQVKKHVRSFHSEKIYQCT 557
           + CI C ++F +   L  H   H  +  F C  C K F    Q+ +H R+   EK Y+C+
Sbjct: 431 HGCIQCGKAFSQKSHLISHQMTHTGEKPFICSKCGKAFSRKSQLVRHQRTHTGEKPYECS 490

Query: 558 ECDKAFCRPDKLRLHMLRHSDRKDFLCSTCGKQFKRKDKLREHMQRMHNPER--EAKKAD 615
           EC KAF     L  H   H+  K ++CS CGK F +K  L  H QR H  E+  E  +  
Sbjct: 491 ECGKAFSEKLSLTNHQRIHTGEKPYVCSECGKAFCQKSHLISH-QRTHTGEKPYECSECG 549

Query: 616 RISRSKTFKPRITSTDYDSFTFKCRLCMMGFRRRGMLVNHLSKRHPDMKIEEVPELTLPI 675
           +    K+       T      ++CR C   F ++  L  H                   I
Sbjct: 550 KAFGEKSSLATHQRTHTGEKPYECRDCEKAFSQKSQLNTHQR-----------------I 592

Query: 676 IKPNRDYFCQYCDKVYKSASKRKAHILKNHPGAELPPSIRKLRPAGPGEPDPMLSTHTQL 735
               + Y C  C K +   S+   H L+ H G E P    + R A   E   +++     
Sbjct: 593 HTGEKPYECSLCRKAFFEKSELIRH-LRTHTG-EKPYECNECRKAF-REKSSLINHQRIH 649

Query: 736 TGTIATPPVCCPHCSKQYSSKTKMVQHIR 764
           TG     P  C  C K +S K+ ++ H R
Sbjct: 650 TG---EKPFECSECGKAFSRKSHLIPHQR 675



 Score =  133 bits (335), Expect = 7e-31
 Identities = 108/344 (31%), Positives = 147/344 (42%), Gaps = 30/344 (8%)

Query: 438 RPFKCLQCGKAFREKDKLDQHLRFHGREGNCPLTCDLCNKGFISSTSLESHMKLHSDQKT 497
           +P+ C QCGKAF +K +L  H R H   G  P  C  C K F   + L SH + H+ +K 
Sbjct: 261 KPYNCSQCGKAFSQKSQLTSHQRTH--TGEKPYECGECGKAFSRKSHLISHWRTHTGEKP 318

Query: 498 YSCIFCPESFDRLDLLKDHVAIHINDGYFTCPTCKKRFPDFIQVKKHVRSFHSEKIYQCT 557
           Y C  C  +F     L +H  IH  +  F C  C K F    Q+  H R+    K + C+
Sbjct: 319 YGCNECGRAFSEKSNLINHQRIHTGEKPFECRECGKAFSRKSQLVTHHRTHTGTKPFGCS 378

Query: 558 ECDKAFCRPDKLRLHMLRHSDRKDFLCSTCGKQFKRKDKLREHMQRMHNPER-----EAK 612
           +C KAF    +L  H   H+  K + CS C K F+ +  L  H QR H  E+     +  
Sbjct: 379 DCRKAFFEKSELIRHQTIHTGEKPYECSECRKAFRERSSLINH-QRTHTGEKPHGCIQCG 437

Query: 613 KADRISRSKTFKPRITSTDYDSFTFKCRLCMMGFRRRGMLVNHLSKRHPDMKIEEVPE-- 670
           KA    +S     ++T T    F   C  C   F R+  LV H  + H   K  E  E  
Sbjct: 438 KAFS-QKSHLISHQMTHTGEKPFI--CSKCGKAFSRKSQLVRH-QRTHTGEKPYECSECG 493

Query: 671 ------LTLP----IIKPNRDYFCQYCDKVYKSASKRKAHILKNHPGAELPPSIRKLRPA 720
                 L+L     I    + Y C  C K +   S   +H  + H G E P    +   A
Sbjct: 494 KAFSEKLSLTNHQRIHTGEKPYVCSECGKAFCQKSHLISH-QRTHTG-EKPYECSECGKA 551

Query: 721 GPGEPDPMLSTHTQLTGTIATPPVCCPHCSKQYSSKTKMVQHIR 764
             GE    L+TH Q T T    P  C  C K +S K+++  H R
Sbjct: 552 F-GEKS-SLATH-QRTHT-GEKPYECRDCEKAFSQKSQLNTHQR 591



 Score =  124 bits (312), Expect = 3e-28
 Identities = 95/330 (28%), Positives = 135/330 (40%), Gaps = 34/330 (10%)

Query: 440 FKCLQCGKAFREKDKLDQHLRFHGREGNCPLTCDLCNKGFISSTSLESHMKLHSDQKTYS 499
           F C  CGK F +K +   H R H   G  P  C  C K F   + L SH + H+ +K Y 
Sbjct: 235 FGCGNCGKTFPQKSQFITHHRTH--TGEKPYNCSQCGKAFSQKSQLTSHQRTHTGEKPYE 292

Query: 500 CIFCPESFDRLDLLKDHVAIHINDGYFTCPTCKKRFPDFIQVKKHVRSFHSEKIYQCTEC 559
           C  C ++F R   L  H   H  +  + C  C + F +   +  H R    EK ++C EC
Sbjct: 293 CGECGKAFSRKSHLISHWRTHTGEKPYGCNECGRAFSEKSNLINHQRIHTGEKPFECREC 352

Query: 560 DKAFCRPDKLRLHMLRHSDRKDFLCSTCGKQFKRKDKLREHMQRMHNPER-----EAKKA 614
            KAF R  +L  H   H+  K F CS C K F  K +L  H Q +H  E+     E +KA
Sbjct: 353 GKAFSRKSQLVTHHRTHTGTKPFGCSDCRKAFFEKSELIRH-QTIHTGEKPYECSECRKA 411

Query: 615 DRISRSKTFKPRITSTDYDSFTFKCRLCMMGFRRRGMLVNHLSKRHPDMKIEEVPELTLP 674
            R  RS     + T T        C  C   F ++  L++H              ++T  
Sbjct: 412 FR-ERSSLINHQRTHT--GEKPHGCIQCGKAFSQKSHLISH--------------QMTHT 454

Query: 675 IIKPNRDYFCQYCDKVYKSASKRKAHILKNHPGAELPPSIRKLRPAGPGEPDPMLSTHTQ 734
             KP   + C  C K +   S+   H  + H G E P    +    G    + +  T+ Q
Sbjct: 455 GEKP---FICSKCGKAFSRKSQLVRH-QRTHTG-EKP---YECSECGKAFSEKLSLTNHQ 506

Query: 735 LTGTIATPPVCCPHCSKQYSSKTKMVQHIR 764
              T    P  C  C K +  K+ ++ H R
Sbjct: 507 RIHT-GEKPYVCSECGKAFCQKSHLISHQR 535



 Score =  120 bits (302), Expect = 5e-27
 Identities = 61/172 (35%), Positives = 87/172 (50%), Gaps = 3/172 (1%)

Query: 438 RPFKCLQCGKAFREKDKLDQHLRFHGREGNCPLTCDLCNKGFISSTSLESHMKLHSDQKT 497
           +P++C  C KAF +K +L+ H R H   G  P  C LC K F   + L  H++ H+ +K 
Sbjct: 569 KPYECRDCEKAFSQKSQLNTHQRIH--TGEKPYECSLCRKAFFEKSELIRHLRTHTGEKP 626

Query: 498 YSCIFCPESFDRLDLLKDHVAIHINDGYFTCPTCKKRFPDFIQVKKHVRSFHSEKIYQCT 557
           Y C  C ++F     L +H  IH  +  F C  C K F     +  H R+   EK Y C+
Sbjct: 627 YECNECRKAFREKSSLINHQRIHTGEKPFECSECGKAFSRKSHLIPHQRTHTGEKPYGCS 686

Query: 558 ECDKAFCRPDKLRLHMLRHSDRKDFLCSTCGKQFKRKDKLREHMQRMHNPER 609
           EC KAF +  +L  H   H+  K + C  CGK F +K +L  H QR H  ++
Sbjct: 687 ECRKAFSQKSQLVNHQRIHTGEKPYRCIECGKAFSQKSQLINH-QRTHTVKK 737



 Score =  108 bits (270), Expect = 3e-23
 Identities = 88/327 (26%), Positives = 126/327 (38%), Gaps = 28/327 (8%)

Query: 441 KCLQCGKAFREKDKLDQHLRFH-GREGNCPLTCDLCNKGFISSTSLESHMKLHSDQKTYS 499
           K   C K ++E  K  Q + +H  R G     C  C K F    SL  H   H     + 
Sbjct: 178 KYYDCDK-YKESYKKSQIIIYHRNRLGEKLYECSECRKRFSKKPSLIKHQSRHIRDIAFG 236

Query: 500 CIFCPESFDRLDLLKDHVAIHINDGYFTCPTCKKRFPDFIQVKKHVRSFHSEKIYQCTEC 559
           C  C ++F +      H   H  +  + C  C K F    Q+  H R+   EK Y+C EC
Sbjct: 237 CGNCGKTFPQKSQFITHHRTHTGEKPYNCSQCGKAFSQKSQLTSHQRTHTGEKPYECGEC 296

Query: 560 DKAFCRPDKLRLHMLRHSDRKDFLCSTCGKQFKRKDKLREHMQRMHNPER--EAKKADRI 617
            KAF R   L  H   H+  K + C+ CG+ F  K  L  H QR+H  E+  E ++  + 
Sbjct: 297 GKAFSRKSHLISHWRTHTGEKPYGCNECGRAFSEKSNLINH-QRIHTGEKPFECRECGKA 355

Query: 618 SRSKTFKPRITSTDYDSFTFKCRLCMMGFRRRGMLVNHLSKRHPDMKIEEVPELTLPIIK 677
              K+       T   +  F C  C   F  +  L+     RH  +   E P        
Sbjct: 356 FSRKSQLVTHHRTHTGTKPFGCSDCRKAFFEKSELI-----RHQTIHTGEKP-------- 402

Query: 678 PNRDYFCQYCDKVYKSASKRKAHILKNHPGAELPPSIRKLRPAGPGEPDPMLSTHTQLTG 737
               Y C  C K ++  S    H  + H G +    I+     G            Q+T 
Sbjct: 403 ----YECSECRKAFRERSSLINH-QRTHTGEKPHGCIQ----CGKAFSQKSHLISHQMTH 453

Query: 738 TIATPPVCCPHCSKQYSSKTKMVQHIR 764
           T    P  C  C K +S K+++V+H R
Sbjct: 454 T-GEKPFICSKCGKAFSRKSQLVRHQR 479



 Score = 78.2 bits (191), Expect = 4e-14
 Identities = 69/290 (23%), Positives = 105/290 (36%), Gaps = 30/290 (10%)

Query: 246 FVNQKIHDISEEERKVLREQ-----EKNWPCYECNRRFISSEQLQQHLNSHDEKLDVFSR 300
           F+  K       + +++R Q     EK + C EC + F     L  H   H  +      
Sbjct: 459 FICSKCGKAFSRKSQLVRHQRTHTGEKPYECSECGKAFSEKLSLTNHQRIHTGEKPYVCS 518

Query: 301 TRGRGRGRGKRRFGPGRRPGRPPKFIRLEITSENGEKSDDGTQDLLHFPTKE-QFDEAEP 359
             G+   +        R       +   E     GEKS   T    H   K  +  + E 
Sbjct: 519 ECGKAFCQKSHLISHQRTHTGEKPYECSECGKAFGEKSSLATHQRTHTGEKPYECRDCEK 578

Query: 360 ATLNGLDQPEQTTIPIPQLPQET---------QSSLEHEPETHTLHLQPQHEESVVPTQS 410
           A            I   + P E          +S L     THT              + 
Sbjct: 579 AFSQKSQLNTHQRIHTGEKPYECSLCRKAFFEKSELIRHLRTHT-------------GEK 625

Query: 411 TLTADDMRRAKRIRNAALQHLFIRKSFRPFKCLQCGKAFREKDKLDQHLRFHGREGNCPL 470
               ++ R+A R +++ + H  I    +PF+C +CGKAF  K  L  H R H   G  P 
Sbjct: 626 PYECNECRKAFREKSSLINHQRIHTGEKPFECSECGKAFSRKSHLIPHQRTH--TGEKPY 683

Query: 471 TCDLCNKGFISSTSLESHMKLHSDQKTYSCIFCPESFDRLDLLKDHVAIH 520
            C  C K F   + L +H ++H+ +K Y CI C ++F +   L +H   H
Sbjct: 684 GCSECRKAFSQKSQLVNHQRIHTGEKPYRCIECGKAFSQKSQLINHQRTH 733


>gi|239747145 PREDICTED: hypothetical protein XP_002343927 isoform 3
           [Homo sapiens]
          Length = 738

 Score =  149 bits (377), Expect = 1e-35
 Identities = 104/370 (28%), Positives = 153/370 (41%), Gaps = 38/370 (10%)

Query: 416 DMRRAKRIRNAALQHLFIRKSFRPFKCLQCGKAFREKDKLDQHLRFHGREGNCPLTCDLC 475
           D R+A   ++  ++H  I    +P++C +C KAFRE+  L  H R H   G  P  C  C
Sbjct: 379 DCRKAFFEKSELIRHQTIHTGEKPYECSECRKAFRERSSLINHQRTH--TGEKPHGCIQC 436

Query: 476 NKGFISSTSLESHMKLHSDQKTYSCIFCPESFDRLDLLKDHVAIHINDGYFTCPTCKKRF 535
            K F   + L SH   H+ +K + C  C ++F R   L  H   H  +  + C  C K F
Sbjct: 437 GKAFSQKSHLISHQMTHTGEKPFICSKCGKAFSRKSQLVRHQRTHTGEKPYECSECGKAF 496

Query: 536 PDFIQVKKHVRSFHSEKIYQCTECDKAFCRPDKLRLHMLRHSDRKDFLCSTCGKQFKRKD 595
            + + +  H R    EK Y C+EC KAFC+   L  H   H+  K + CS CGK F  K 
Sbjct: 497 SEKLSLTNHQRIHTGEKPYVCSECGKAFCQKSHLISHQRTHTGEKPYECSECGKAFGEKS 556

Query: 596 KLREHMQRMHNPER--EAKKADRISRSKTFKPRITSTDYDSFTFKCRLCMMGFRRRGMLV 653
            L  H QR H  E+  E +  ++    K+              ++C LC   F  +  L+
Sbjct: 557 SLATH-QRTHTGEKPYECRDCEKAFSQKSQLNTHQRIHTGEKPYECSLCRKAFFEKSELI 615

Query: 654 NHLSKRHPDMKIEEVPELTLP------------IIKPNRDYFCQYCDKVYKSASKRKAHI 701
            HL + H   K  E  E                I    + + C  C K +     RK+H+
Sbjct: 616 RHL-RTHTGEKPYECNECRKAFREKSSLINHQRIHTGEKPFECSECGKAF----SRKSHL 670

Query: 702 L---KNHPGAELPPSIRKLRPAGPGEPDPMLSTHTQLTG----TIATPPVCCPHCSKQYS 754
           +   + H G          +P G  E     S  +QL           P  C  C K +S
Sbjct: 671 IPHQRTHTGE---------KPYGCSECRKAFSQKSQLVNHQRIHTGEKPYRCIECGKAFS 721

Query: 755 SKTKMVQHIR 764
            K++++ H R
Sbjct: 722 QKSQLINHQR 731



 Score =  141 bits (355), Expect = 4e-33
 Identities = 95/333 (28%), Positives = 146/333 (43%), Gaps = 36/333 (10%)

Query: 438 RPFKCLQCGKAFREKDKLDQHLRFHGREGNCPLTCDLCNKGFISSTSLESHMKLHSDQKT 497
           +P+ C +CG+AF EK  L  H R H   G  P  C  C K F   + L +H + H+  K 
Sbjct: 317 KPYGCNECGRAFSEKSNLINHQRIH--TGEKPFECRECGKAFSRKSQLVTHHRTHTGTKP 374

Query: 498 YSCIFCPESFDRLDLLKDHVAIHINDGYFTCPTCKKRFPDFIQVKKHVRSFHSEKIYQCT 557
           + C  C ++F     L  H  IH  +  + C  C+K F +   +  H R+   EK + C 
Sbjct: 375 FGCSDCRKAFFEKSELIRHQTIHTGEKPYECSECRKAFRERSSLINHQRTHTGEKPHGCI 434

Query: 558 ECDKAFCRPDKLRLHMLRHSDRKDFLCSTCGKQFKRKDKLREHMQRMHNPEREAKKADRI 617
           +C KAF +   L  H + H+  K F+CS CGK F RK +L  H QR H  E+  + ++  
Sbjct: 435 QCGKAFSQKSHLISHQMTHTGEKPFICSKCGKAFSRKSQLVRH-QRTHTGEKPYECSE-- 491

Query: 618 SRSKTFKPRITSTDYDSF-----TFKCRLCMMGFRRRGMLVNHLSKRHPDMKIEEVPELT 672
              K F  +++ T++         + C  C   F ++  L++H  + H   K        
Sbjct: 492 -CGKAFSEKLSLTNHQRIHTGEKPYVCSECGKAFCQKSHLISH-QRTHTGEK-------- 541

Query: 673 LPIIKPNRDYFCQYCDKVYKSASKRKAHILKNHPGAELPPSIRKLRPAGPGEPDPMLSTH 732
                    Y C  C K +   S    H  + H G E P   R    A        L+TH
Sbjct: 542 --------PYECSECGKAFGEKSSLATH-QRTHTG-EKPYECRDCEKA--FSQKSQLNTH 589

Query: 733 TQL-TGTIATPPVCCPHCSKQYSSKTKMVQHIR 764
            ++ TG     P  C  C K +  K+++++H+R
Sbjct: 590 QRIHTG---EKPYECSLCRKAFFEKSELIRHLR 619



 Score =  140 bits (354), Expect = 5e-33
 Identities = 98/329 (29%), Positives = 140/329 (42%), Gaps = 28/329 (8%)

Query: 438 RPFKCLQCGKAFREKDKLDQHLRFHGREGNCPLTCDLCNKGFISSTSLESHMKLHSDQKT 497
           +PF C  C KAF EK +L +H   H   G  P  C  C K F   +SL +H + H+ +K 
Sbjct: 373 KPFGCSDCRKAFFEKSELIRHQTIH--TGEKPYECSECRKAFRERSSLINHQRTHTGEKP 430

Query: 498 YSCIFCPESFDRLDLLKDHVAIHINDGYFTCPTCKKRFPDFIQVKKHVRSFHSEKIYQCT 557
           + CI C ++F +   L  H   H  +  F C  C K F    Q+ +H R+   EK Y+C+
Sbjct: 431 HGCIQCGKAFSQKSHLISHQMTHTGEKPFICSKCGKAFSRKSQLVRHQRTHTGEKPYECS 490

Query: 558 ECDKAFCRPDKLRLHMLRHSDRKDFLCSTCGKQFKRKDKLREHMQRMHNPER--EAKKAD 615
           EC KAF     L  H   H+  K ++CS CGK F +K  L  H QR H  E+  E  +  
Sbjct: 491 ECGKAFSEKLSLTNHQRIHTGEKPYVCSECGKAFCQKSHLISH-QRTHTGEKPYECSECG 549

Query: 616 RISRSKTFKPRITSTDYDSFTFKCRLCMMGFRRRGMLVNHLSKRHPDMKIEEVPELTLPI 675
           +    K+       T      ++CR C   F ++  L  H                   I
Sbjct: 550 KAFGEKSSLATHQRTHTGEKPYECRDCEKAFSQKSQLNTHQR-----------------I 592

Query: 676 IKPNRDYFCQYCDKVYKSASKRKAHILKNHPGAELPPSIRKLRPAGPGEPDPMLSTHTQL 735
               + Y C  C K +   S+   H L+ H G E P    + R A   E   +++     
Sbjct: 593 HTGEKPYECSLCRKAFFEKSELIRH-LRTHTG-EKPYECNECRKAF-REKSSLINHQRIH 649

Query: 736 TGTIATPPVCCPHCSKQYSSKTKMVQHIR 764
           TG     P  C  C K +S K+ ++ H R
Sbjct: 650 TG---EKPFECSECGKAFSRKSHLIPHQR 675



 Score =  133 bits (335), Expect = 7e-31
 Identities = 108/344 (31%), Positives = 147/344 (42%), Gaps = 30/344 (8%)

Query: 438 RPFKCLQCGKAFREKDKLDQHLRFHGREGNCPLTCDLCNKGFISSTSLESHMKLHSDQKT 497
           +P+ C QCGKAF +K +L  H R H   G  P  C  C K F   + L SH + H+ +K 
Sbjct: 261 KPYNCSQCGKAFSQKSQLTSHQRTH--TGEKPYECGECGKAFSRKSHLISHWRTHTGEKP 318

Query: 498 YSCIFCPESFDRLDLLKDHVAIHINDGYFTCPTCKKRFPDFIQVKKHVRSFHSEKIYQCT 557
           Y C  C  +F     L +H  IH  +  F C  C K F    Q+  H R+    K + C+
Sbjct: 319 YGCNECGRAFSEKSNLINHQRIHTGEKPFECRECGKAFSRKSQLVTHHRTHTGTKPFGCS 378

Query: 558 ECDKAFCRPDKLRLHMLRHSDRKDFLCSTCGKQFKRKDKLREHMQRMHNPER-----EAK 612
           +C KAF    +L  H   H+  K + CS C K F+ +  L  H QR H  E+     +  
Sbjct: 379 DCRKAFFEKSELIRHQTIHTGEKPYECSECRKAFRERSSLINH-QRTHTGEKPHGCIQCG 437

Query: 613 KADRISRSKTFKPRITSTDYDSFTFKCRLCMMGFRRRGMLVNHLSKRHPDMKIEEVPE-- 670
           KA    +S     ++T T    F   C  C   F R+  LV H  + H   K  E  E  
Sbjct: 438 KAFS-QKSHLISHQMTHTGEKPFI--CSKCGKAFSRKSQLVRH-QRTHTGEKPYECSECG 493

Query: 671 ------LTLP----IIKPNRDYFCQYCDKVYKSASKRKAHILKNHPGAELPPSIRKLRPA 720
                 L+L     I    + Y C  C K +   S   +H  + H G E P    +   A
Sbjct: 494 KAFSEKLSLTNHQRIHTGEKPYVCSECGKAFCQKSHLISH-QRTHTG-EKPYECSECGKA 551

Query: 721 GPGEPDPMLSTHTQLTGTIATPPVCCPHCSKQYSSKTKMVQHIR 764
             GE    L+TH Q T T    P  C  C K +S K+++  H R
Sbjct: 552 F-GEKS-SLATH-QRTHT-GEKPYECRDCEKAFSQKSQLNTHQR 591



 Score =  124 bits (312), Expect = 3e-28
 Identities = 95/330 (28%), Positives = 135/330 (40%), Gaps = 34/330 (10%)

Query: 440 FKCLQCGKAFREKDKLDQHLRFHGREGNCPLTCDLCNKGFISSTSLESHMKLHSDQKTYS 499
           F C  CGK F +K +   H R H   G  P  C  C K F   + L SH + H+ +K Y 
Sbjct: 235 FGCGNCGKTFPQKSQFITHHRTH--TGEKPYNCSQCGKAFSQKSQLTSHQRTHTGEKPYE 292

Query: 500 CIFCPESFDRLDLLKDHVAIHINDGYFTCPTCKKRFPDFIQVKKHVRSFHSEKIYQCTEC 559
           C  C ++F R   L  H   H  +  + C  C + F +   +  H R    EK ++C EC
Sbjct: 293 CGECGKAFSRKSHLISHWRTHTGEKPYGCNECGRAFSEKSNLINHQRIHTGEKPFECREC 352

Query: 560 DKAFCRPDKLRLHMLRHSDRKDFLCSTCGKQFKRKDKLREHMQRMHNPER-----EAKKA 614
            KAF R  +L  H   H+  K F CS C K F  K +L  H Q +H  E+     E +KA
Sbjct: 353 GKAFSRKSQLVTHHRTHTGTKPFGCSDCRKAFFEKSELIRH-QTIHTGEKPYECSECRKA 411

Query: 615 DRISRSKTFKPRITSTDYDSFTFKCRLCMMGFRRRGMLVNHLSKRHPDMKIEEVPELTLP 674
            R  RS     + T T        C  C   F ++  L++H              ++T  
Sbjct: 412 FR-ERSSLINHQRTHT--GEKPHGCIQCGKAFSQKSHLISH--------------QMTHT 454

Query: 675 IIKPNRDYFCQYCDKVYKSASKRKAHILKNHPGAELPPSIRKLRPAGPGEPDPMLSTHTQ 734
             KP   + C  C K +   S+   H  + H G E P    +    G    + +  T+ Q
Sbjct: 455 GEKP---FICSKCGKAFSRKSQLVRH-QRTHTG-EKP---YECSECGKAFSEKLSLTNHQ 506

Query: 735 LTGTIATPPVCCPHCSKQYSSKTKMVQHIR 764
              T    P  C  C K +  K+ ++ H R
Sbjct: 507 RIHT-GEKPYVCSECGKAFCQKSHLISHQR 535



 Score =  120 bits (302), Expect = 5e-27
 Identities = 61/172 (35%), Positives = 87/172 (50%), Gaps = 3/172 (1%)

Query: 438 RPFKCLQCGKAFREKDKLDQHLRFHGREGNCPLTCDLCNKGFISSTSLESHMKLHSDQKT 497
           +P++C  C KAF +K +L+ H R H   G  P  C LC K F   + L  H++ H+ +K 
Sbjct: 569 KPYECRDCEKAFSQKSQLNTHQRIH--TGEKPYECSLCRKAFFEKSELIRHLRTHTGEKP 626

Query: 498 YSCIFCPESFDRLDLLKDHVAIHINDGYFTCPTCKKRFPDFIQVKKHVRSFHSEKIYQCT 557
           Y C  C ++F     L +H  IH  +  F C  C K F     +  H R+   EK Y C+
Sbjct: 627 YECNECRKAFREKSSLINHQRIHTGEKPFECSECGKAFSRKSHLIPHQRTHTGEKPYGCS 686

Query: 558 ECDKAFCRPDKLRLHMLRHSDRKDFLCSTCGKQFKRKDKLREHMQRMHNPER 609
           EC KAF +  +L  H   H+  K + C  CGK F +K +L  H QR H  ++
Sbjct: 687 ECRKAFSQKSQLVNHQRIHTGEKPYRCIECGKAFSQKSQLINH-QRTHTVKK 737



 Score =  108 bits (270), Expect = 3e-23
 Identities = 88/327 (26%), Positives = 126/327 (38%), Gaps = 28/327 (8%)

Query: 441 KCLQCGKAFREKDKLDQHLRFH-GREGNCPLTCDLCNKGFISSTSLESHMKLHSDQKTYS 499
           K   C K ++E  K  Q + +H  R G     C  C K F    SL  H   H     + 
Sbjct: 178 KYYDCDK-YKESYKKSQIIIYHRNRLGEKLYECSECRKRFSKKPSLIKHQSRHIRDIAFG 236

Query: 500 CIFCPESFDRLDLLKDHVAIHINDGYFTCPTCKKRFPDFIQVKKHVRSFHSEKIYQCTEC 559
           C  C ++F +      H   H  +  + C  C K F    Q+  H R+   EK Y+C EC
Sbjct: 237 CGNCGKTFPQKSQFITHHRTHTGEKPYNCSQCGKAFSQKSQLTSHQRTHTGEKPYECGEC 296

Query: 560 DKAFCRPDKLRLHMLRHSDRKDFLCSTCGKQFKRKDKLREHMQRMHNPER--EAKKADRI 617
            KAF R   L  H   H+  K + C+ CG+ F  K  L  H QR+H  E+  E ++  + 
Sbjct: 297 GKAFSRKSHLISHWRTHTGEKPYGCNECGRAFSEKSNLINH-QRIHTGEKPFECRECGKA 355

Query: 618 SRSKTFKPRITSTDYDSFTFKCRLCMMGFRRRGMLVNHLSKRHPDMKIEEVPELTLPIIK 677
              K+       T   +  F C  C   F  +  L+     RH  +   E P        
Sbjct: 356 FSRKSQLVTHHRTHTGTKPFGCSDCRKAFFEKSELI-----RHQTIHTGEKP-------- 402

Query: 678 PNRDYFCQYCDKVYKSASKRKAHILKNHPGAELPPSIRKLRPAGPGEPDPMLSTHTQLTG 737
               Y C  C K ++  S    H  + H G +    I+     G            Q+T 
Sbjct: 403 ----YECSECRKAFRERSSLINH-QRTHTGEKPHGCIQ----CGKAFSQKSHLISHQMTH 453

Query: 738 TIATPPVCCPHCSKQYSSKTKMVQHIR 764
           T    P  C  C K +S K+++V+H R
Sbjct: 454 T-GEKPFICSKCGKAFSRKSQLVRHQR 479



 Score = 78.2 bits (191), Expect = 4e-14
 Identities = 69/290 (23%), Positives = 105/290 (36%), Gaps = 30/290 (10%)

Query: 246 FVNQKIHDISEEERKVLREQ-----EKNWPCYECNRRFISSEQLQQHLNSHDEKLDVFSR 300
           F+  K       + +++R Q     EK + C EC + F     L  H   H  +      
Sbjct: 459 FICSKCGKAFSRKSQLVRHQRTHTGEKPYECSECGKAFSEKLSLTNHQRIHTGEKPYVCS 518

Query: 301 TRGRGRGRGKRRFGPGRRPGRPPKFIRLEITSENGEKSDDGTQDLLHFPTKE-QFDEAEP 359
             G+   +        R       +   E     GEKS   T    H   K  +  + E 
Sbjct: 519 ECGKAFCQKSHLISHQRTHTGEKPYECSECGKAFGEKSSLATHQRTHTGEKPYECRDCEK 578

Query: 360 ATLNGLDQPEQTTIPIPQLPQET---------QSSLEHEPETHTLHLQPQHEESVVPTQS 410
           A            I   + P E          +S L     THT              + 
Sbjct: 579 AFSQKSQLNTHQRIHTGEKPYECSLCRKAFFEKSELIRHLRTHT-------------GEK 625

Query: 411 TLTADDMRRAKRIRNAALQHLFIRKSFRPFKCLQCGKAFREKDKLDQHLRFHGREGNCPL 470
               ++ R+A R +++ + H  I    +PF+C +CGKAF  K  L  H R H   G  P 
Sbjct: 626 PYECNECRKAFREKSSLINHQRIHTGEKPFECSECGKAFSRKSHLIPHQRTH--TGEKPY 683

Query: 471 TCDLCNKGFISSTSLESHMKLHSDQKTYSCIFCPESFDRLDLLKDHVAIH 520
            C  C K F   + L +H ++H+ +K Y CI C ++F +   L +H   H
Sbjct: 684 GCSECRKAFSQKSQLVNHQRIHTGEKPYRCIECGKAFSQKSQLINHQRTH 733


>gi|170932473 zinc finger protein 786 [Homo sapiens]
          Length = 782

 Score =  149 bits (377), Expect = 1e-35
 Identities = 103/345 (29%), Positives = 148/345 (42%), Gaps = 61/345 (17%)

Query: 422 RIRNAALQHLFIRKSFRPFKCLQCGKAFREKDKLDQHLRFHGREGNCPLTCDLCNKGFIS 481
           R+R     H       RPF C +CGK F ++ KL +H+R H   G  P  C  C + F  
Sbjct: 407 RLRRLLQVHQHAHGGERPFSCRKCGKGFAKQCKLTEHIRVH--SGEKPFRCAKCGRNFRQ 464

Query: 482 STSLESHMKLHSDQKTYSCIFCPESFDRLDLLKDHVAIHINDGYFTCPTCKKRFPDFIQV 541
              L  H +LH+D+K + C  C  SF    +L+ H   H  +  F+C  C + F    ++
Sbjct: 465 RGQLLRHQRLHTDEKPFQCPECGLSFRLESMLRAHRLRHGGERPFSCSECGRGFTHQCKL 524

Query: 542 KKHVRSFHSEKIYQCTECDKAFCRPDKLRLHMLRHSDRKDFLCSTCGKQFKRKDKLREHM 601
           ++H+R    E+ +QC +CDK F     L+ H   HS  + F C  CGK F R+ KL EH+
Sbjct: 525 REHLRVHSGERPFQCLKCDKRFRLKGILKAHQHTHSKERPFSCGECGKGFTRQSKLTEHL 584

Query: 602 QRMHNPEREAKKADRISRSKTFKPRITSTDYDSFTFKCRLCMMGFRRRGMLVNHLSKRHP 661
            R+H+ ER                           F+C  C   FR +G L++H  + H 
Sbjct: 585 -RVHSGER--------------------------PFQCPECNRSFRLKGQLLSH-QRLHT 616

Query: 662 DMKIEEVPELTLPIIKPNRDYFCQYCDKVYKSASKRKAHILKNHPGAELPPSIRKLRPAG 721
                             R + C  CDK Y+  +  KAH L  H G E+P S       G
Sbjct: 617 G----------------ERPFQCPECDKRYRVKADMKAHQLL-HSG-EMPFSCE----CG 654

Query: 722 PGEPDPMLSTHTQLTGTIAT----PPVCCPHCSKQYSSKTKMVQH 762
            G        H++L   I T     P  CP C K +  K +++ H
Sbjct: 655 KG-----FVKHSKLIEHIRTHTGEKPFQCPKCDKSFRLKAQLLSH 694



 Score =  120 bits (300), Expect = 9e-27
 Identities = 62/188 (32%), Positives = 94/188 (50%), Gaps = 4/188 (2%)

Query: 422 RIRNAALQHLFIRKSFRPFKCLQCGKAFREKDKLDQHLRFHGREGNCPLTCDLCNKGFIS 481
           R++     H       RPF C +CGK F  + KL +HLR H   G  P  C  CN+ F  
Sbjct: 547 RLKGILKAHQHTHSKERPFSCGECGKGFTRQSKLTEHLRVH--SGERPFQCPECNRSFRL 604

Query: 482 STSLESHMKLHSDQKTYSCIFCPESFDRLDLLKDHVAIHINDGYFTCPTCKKRFPDFIQV 541
              L SH +LH+ ++ + C  C + +     +K H  +H  +  F+C  C K F    ++
Sbjct: 605 KGQLLSHQRLHTGERPFQCPECDKRYRVKADMKAHQLLHSGEMPFSC-ECGKGFVKHSKL 663

Query: 542 KKHVRSFHSEKIYQCTECDKAFCRPDKLRLHMLRHSDRKDFLCSTCGKQFKRKDKLREHM 601
            +H+R+   EK +QC +CDK+F    +L  H   H+  + F C  C K F+ +  +  H 
Sbjct: 664 IEHIRTHTGEKPFQCPKCDKSFRLKAQLLSHQGLHTGERPFHCPECDKNFRERGHMLRH- 722

Query: 602 QRMHNPER 609
           QR+H PER
Sbjct: 723 QRIHRPER 730



 Score =  112 bits (280), Expect = 2e-24
 Identities = 60/177 (33%), Positives = 86/177 (48%), Gaps = 4/177 (2%)

Query: 429 QHLFIRKSFRPFKCLQCGKAFREKDKLDQHLRFHGREGNCPLTCDLCNKGFISSTSLESH 488
           +HL +    RPF+C +C ++FR K +L  H R H   G  P  C  C+K +     +++H
Sbjct: 582 EHLRVHSGERPFQCPECNRSFRLKGQLLSHQRLH--TGERPFQCPECDKRYRVKADMKAH 639

Query: 489 MKLHSDQKTYSCIFCPESFDRLDLLKDHVAIHINDGYFTCPTCKKRFPDFIQVKKHVRSF 548
             LHS +  +SC  C + F +   L +H+  H  +  F CP C K F    Q+  H    
Sbjct: 640 QLLHSGEMPFSCE-CGKGFVKHSKLIEHIRTHTGEKPFQCPKCDKSFRLKAQLLSHQGLH 698

Query: 549 HSEKIYQCTECDKAFCRPDKLRLHMLRHSDRKDFLCSTCGKQFKRKDKLREHMQRMH 605
             E+ + C ECDK F     +  H   H   + F C  CGK F  K KL EH+ R+H
Sbjct: 699 TGERPFHCPECDKNFRERGHMLRHQRIHRPERPFACGDCGKGFIYKSKLAEHI-RVH 754



 Score = 98.6 bits (244), Expect = 3e-20
 Identities = 49/162 (30%), Positives = 78/162 (48%), Gaps = 3/162 (1%)

Query: 416 DMRRAKRIRNAALQHLFIRKSFRPFKCLQCGKAFREKDKLDQHLRFHGREGNCPLTCDLC 475
           +  R+ R++   L H  +    RPF+C +C K +R K  +  H   H   G  P +C+ C
Sbjct: 597 ECNRSFRLKGQLLSHQRLHTGERPFQCPECDKRYRVKADMKAHQLLHS--GEMPFSCE-C 653

Query: 476 NKGFISSTSLESHMKLHSDQKTYSCIFCPESFDRLDLLKDHVAIHINDGYFTCPTCKKRF 535
            KGF+  + L  H++ H+ +K + C  C +SF     L  H  +H  +  F CP C K F
Sbjct: 654 GKGFVKHSKLIEHIRTHTGEKPFQCPKCDKSFRLKAQLLSHQGLHTGERPFHCPECDKNF 713

Query: 536 PDFIQVKKHVRSFHSEKIYQCTECDKAFCRPDKLRLHMLRHS 577
            +   + +H R    E+ + C +C K F    KL  H+  H+
Sbjct: 714 RERGHMLRHQRIHRPERPFACGDCGKGFIYKSKLAEHIRVHT 755



 Score = 86.7 bits (213), Expect = 1e-16
 Identities = 90/370 (24%), Positives = 133/370 (35%), Gaps = 53/370 (14%)

Query: 430 HLFIRKSFRPFKCLQCGKAFREKDKLDQHLRFHGREGNCPLTCDLCNKGFISSTSLESHM 489
           H   ++  +P +C  CGK     D        H REG          +G  +S+S+ S  
Sbjct: 286 HRLPQQGEKPAQCTPCGKRSLPVDSTQARRCQHSREGPASW-----REGRGASSSVHSGQ 340

Query: 490 K--------------------LHSDQKTYSCIFCPESFDRLDLLKDHVAIHINDGYFTCP 529
           K                     H  +   SC  C E       L      H  +  F C 
Sbjct: 341 KPGSRLPQEGNSHQEGDTEALQHGAEGPCSCSECGERSPMSARLASPCRAHTGEKPFQCA 400

Query: 530 TCKKRFPDFIQVKKHVRSFHSEKIYQCTECDKAFCRPDKLRLHMLRHSDRKDFLCSTCGK 589
            C KRF     ++ H  +   E+ + C +C K F +  KL  H+  HS  K F C+ CG+
Sbjct: 401 HCTKRFRLRRLLQVHQHAHGGERPFSCRKCGKGFAKQCKLTEHIRVHSGEKPFRCAKCGR 460

Query: 590 QFKRKDKLREHMQRMHNPER--EAKKADRISRSKTFKPRITSTDYDSFTFKCRLCMMGFR 647
            F+++ +L  H QR+H  E+  +  +     R ++              F C  C  GF 
Sbjct: 461 NFRQRGQLLRH-QRLHTDEKPFQCPECGLSFRLESMLRAHRLRHGGERPFSCSECGRGFT 519

Query: 648 RRGMLVNHLS-----------KRHPDMKIEEVPELTLPIIKPNRDYFCQYCDKVYKSASK 696
            +  L  HL            K     +++ + +         R + C  C K +   SK
Sbjct: 520 HQCKLREHLRVHSGERPFQCLKCDKRFRLKGILKAHQHTHSKERPFSCGECGKGFTRQSK 579

Query: 697 RKAHILKNHPGA---ELPPSIRKLRPAGPGEPDPMLSTHTQL-TGTIATPPVCCPHCSKQ 752
              H L+ H G    + P   R  R  G       L +H +L TG     P  CP C K+
Sbjct: 580 LTEH-LRVHSGERPFQCPECNRSFRLKG------QLLSHQRLHTG---ERPFQCPECDKR 629

Query: 753 YSSKTKMVQH 762
           Y  K  M  H
Sbjct: 630 YRVKADMKAH 639



 Score = 46.2 bits (108), Expect = 2e-04
 Identities = 49/215 (22%), Positives = 79/215 (36%), Gaps = 16/215 (7%)

Query: 265 QEKNWPCYECNRRFISSEQLQQHLNSHDEKL-----DVFSRTRGRGRGRGKRRFGPGRRP 319
           +E+ + C EC + F    +L +HL  H  +      +     R +G+    +R   G RP
Sbjct: 561 KERPFSCGECGKGFTRQSKLTEHLRVHSGERPFQCPECNRSFRLKGQLLSHQRLHTGERP 620

Query: 320 GRPPKFIRLEITSENGEKSDDGTQDLLHFPTKEQFDEAEPATLNGLDQPEQTTIPIPQLP 379
            + P     E       K+D     LLH        E     +      E       + P
Sbjct: 621 FQCP-----ECDKRYRVKADMKAHQLLHSGEMPFSCECGKGFVKHSKLIEHIRTHTGEKP 675

Query: 380 QETQSSLEHEPETHTLHLQPQHEESVVPTQSTLTADDMRRAKRIRNAALQHLFIRKSFRP 439
            +         ++  L  Q    + +   +      +  +  R R   L+H  I +  RP
Sbjct: 676 FQCPKC----DKSFRLKAQLLSHQGLHTGERPFHCPECDKNFRERGHMLRHQRIHRPERP 731

Query: 440 FKCLQCGKAFREKDKLDQHLRFHGREGNCPLTCDL 474
           F C  CGK F  K KL +H+R H +  +CP   +L
Sbjct: 732 FACGDCGKGFIYKSKLAEHIRVHTK--SCPAPNEL 764



 Score = 37.4 bits (85), Expect = 0.073
 Identities = 36/135 (26%), Positives = 51/135 (37%), Gaps = 9/135 (6%)

Query: 445 CGKAFREKDKLDQHLRFHGREGNCPLTCDLCNKGFISSTSLESHMKLHSD--QKTYSCIF 502
           CG++  E + L  H R H ++       +  NK        E+ M   S   Q+ + C  
Sbjct: 192 CGESCWENNHLVMHQRGHSKD-RTRRAWEKFNK------RAETQMPWSSPRVQRHFRCGV 244

Query: 503 CPESFDRLDLLKDHVAIHINDGYFTCPTCKKRFPDFIQVKKHVRSFHSEKIYQCTECDKA 562
           C +SF R   L  H+A H   G F     +  F   +    H      EK  QCT C K 
Sbjct: 245 CGKSFRRKLCLLRHLAAHTGRGPFRNADGEMCFRHELTHPSHRLPQQGEKPAQCTPCGKR 304

Query: 563 FCRPDKLRLHMLRHS 577
               D  +    +HS
Sbjct: 305 SLPVDSTQARRCQHS 319


>gi|188497655 zinc finger protein 84 [Homo sapiens]
          Length = 738

 Score =  149 bits (377), Expect = 1e-35
 Identities = 104/370 (28%), Positives = 153/370 (41%), Gaps = 38/370 (10%)

Query: 416 DMRRAKRIRNAALQHLFIRKSFRPFKCLQCGKAFREKDKLDQHLRFHGREGNCPLTCDLC 475
           D R+A   ++  ++H  I    +P++C +C KAFRE+  L  H R H   G  P  C  C
Sbjct: 379 DCRKAFFEKSELIRHQTIHTGEKPYECSECRKAFRERSSLINHQRTH--TGEKPHGCIQC 436

Query: 476 NKGFISSTSLESHMKLHSDQKTYSCIFCPESFDRLDLLKDHVAIHINDGYFTCPTCKKRF 535
            K F   + L SH   H+ +K + C  C ++F R   L  H   H  +  + C  C K F
Sbjct: 437 GKAFSQKSHLISHQMTHTGEKPFICSKCGKAFSRKSQLVRHQRTHTGEKPYECSECGKAF 496

Query: 536 PDFIQVKKHVRSFHSEKIYQCTECDKAFCRPDKLRLHMLRHSDRKDFLCSTCGKQFKRKD 595
            + + +  H R    EK Y C+EC KAFC+   L  H   H+  K + CS CGK F  K 
Sbjct: 497 SEKLSLTNHQRIHTGEKPYVCSECGKAFCQKSHLISHQRTHTGEKPYECSECGKAFGEKS 556

Query: 596 KLREHMQRMHNPER--EAKKADRISRSKTFKPRITSTDYDSFTFKCRLCMMGFRRRGMLV 653
            L  H QR H  E+  E +  ++    K+              ++C LC   F  +  L+
Sbjct: 557 SLATH-QRTHTGEKPYECRDCEKAFSQKSQLNTHQRIHTGEKPYECSLCRKAFFEKSELI 615

Query: 654 NHLSKRHPDMKIEEVPELTLP------------IIKPNRDYFCQYCDKVYKSASKRKAHI 701
            HL + H   K  E  E                I    + + C  C K +     RK+H+
Sbjct: 616 RHL-RTHTGEKPYECNECRKAFREKSSLINHQRIHTGEKPFECSECGKAF----SRKSHL 670

Query: 702 L---KNHPGAELPPSIRKLRPAGPGEPDPMLSTHTQLTG----TIATPPVCCPHCSKQYS 754
           +   + H G          +P G  E     S  +QL           P  C  C K +S
Sbjct: 671 IPHQRTHTGE---------KPYGCSECRKAFSQKSQLVNHQRIHTGEKPYRCIECGKAFS 721

Query: 755 SKTKMVQHIR 764
            K++++ H R
Sbjct: 722 QKSQLINHQR 731



 Score =  141 bits (355), Expect = 4e-33
 Identities = 95/333 (28%), Positives = 146/333 (43%), Gaps = 36/333 (10%)

Query: 438 RPFKCLQCGKAFREKDKLDQHLRFHGREGNCPLTCDLCNKGFISSTSLESHMKLHSDQKT 497
           +P+ C +CG+AF EK  L  H R H   G  P  C  C K F   + L +H + H+  K 
Sbjct: 317 KPYGCNECGRAFSEKSNLINHQRIH--TGEKPFECRECGKAFSRKSQLVTHHRTHTGTKP 374

Query: 498 YSCIFCPESFDRLDLLKDHVAIHINDGYFTCPTCKKRFPDFIQVKKHVRSFHSEKIYQCT 557
           + C  C ++F     L  H  IH  +  + C  C+K F +   +  H R+   EK + C 
Sbjct: 375 FGCSDCRKAFFEKSELIRHQTIHTGEKPYECSECRKAFRERSSLINHQRTHTGEKPHGCI 434

Query: 558 ECDKAFCRPDKLRLHMLRHSDRKDFLCSTCGKQFKRKDKLREHMQRMHNPEREAKKADRI 617
           +C KAF +   L  H + H+  K F+CS CGK F RK +L  H QR H  E+  + ++  
Sbjct: 435 QCGKAFSQKSHLISHQMTHTGEKPFICSKCGKAFSRKSQLVRH-QRTHTGEKPYECSE-- 491

Query: 618 SRSKTFKPRITSTDYDSF-----TFKCRLCMMGFRRRGMLVNHLSKRHPDMKIEEVPELT 672
              K F  +++ T++         + C  C   F ++  L++H  + H   K        
Sbjct: 492 -CGKAFSEKLSLTNHQRIHTGEKPYVCSECGKAFCQKSHLISH-QRTHTGEK-------- 541

Query: 673 LPIIKPNRDYFCQYCDKVYKSASKRKAHILKNHPGAELPPSIRKLRPAGPGEPDPMLSTH 732
                    Y C  C K +   S    H  + H G E P   R    A        L+TH
Sbjct: 542 --------PYECSECGKAFGEKSSLATH-QRTHTG-EKPYECRDCEKA--FSQKSQLNTH 589

Query: 733 TQL-TGTIATPPVCCPHCSKQYSSKTKMVQHIR 764
            ++ TG     P  C  C K +  K+++++H+R
Sbjct: 590 QRIHTG---EKPYECSLCRKAFFEKSELIRHLR 619



 Score =  140 bits (354), Expect = 5e-33
 Identities = 98/329 (29%), Positives = 140/329 (42%), Gaps = 28/329 (8%)

Query: 438 RPFKCLQCGKAFREKDKLDQHLRFHGREGNCPLTCDLCNKGFISSTSLESHMKLHSDQKT 497
           +PF C  C KAF EK +L +H   H   G  P  C  C K F   +SL +H + H+ +K 
Sbjct: 373 KPFGCSDCRKAFFEKSELIRHQTIH--TGEKPYECSECRKAFRERSSLINHQRTHTGEKP 430

Query: 498 YSCIFCPESFDRLDLLKDHVAIHINDGYFTCPTCKKRFPDFIQVKKHVRSFHSEKIYQCT 557
           + CI C ++F +   L  H   H  +  F C  C K F    Q+ +H R+   EK Y+C+
Sbjct: 431 HGCIQCGKAFSQKSHLISHQMTHTGEKPFICSKCGKAFSRKSQLVRHQRTHTGEKPYECS 490

Query: 558 ECDKAFCRPDKLRLHMLRHSDRKDFLCSTCGKQFKRKDKLREHMQRMHNPER--EAKKAD 615
           EC KAF     L  H   H+  K ++CS CGK F +K  L  H QR H  E+  E  +  
Sbjct: 491 ECGKAFSEKLSLTNHQRIHTGEKPYVCSECGKAFCQKSHLISH-QRTHTGEKPYECSECG 549

Query: 616 RISRSKTFKPRITSTDYDSFTFKCRLCMMGFRRRGMLVNHLSKRHPDMKIEEVPELTLPI 675
           +    K+       T      ++CR C   F ++  L  H                   I
Sbjct: 550 KAFGEKSSLATHQRTHTGEKPYECRDCEKAFSQKSQLNTHQR-----------------I 592

Query: 676 IKPNRDYFCQYCDKVYKSASKRKAHILKNHPGAELPPSIRKLRPAGPGEPDPMLSTHTQL 735
               + Y C  C K +   S+   H L+ H G E P    + R A   E   +++     
Sbjct: 593 HTGEKPYECSLCRKAFFEKSELIRH-LRTHTG-EKPYECNECRKAF-REKSSLINHQRIH 649

Query: 736 TGTIATPPVCCPHCSKQYSSKTKMVQHIR 764
           TG     P  C  C K +S K+ ++ H R
Sbjct: 650 TG---EKPFECSECGKAFSRKSHLIPHQR 675



 Score =  133 bits (335), Expect = 7e-31
 Identities = 108/344 (31%), Positives = 147/344 (42%), Gaps = 30/344 (8%)

Query: 438 RPFKCLQCGKAFREKDKLDQHLRFHGREGNCPLTCDLCNKGFISSTSLESHMKLHSDQKT 497
           +P+ C QCGKAF +K +L  H R H   G  P  C  C K F   + L SH + H+ +K 
Sbjct: 261 KPYNCSQCGKAFSQKSQLTSHQRTH--TGEKPYECGECGKAFSRKSHLISHWRTHTGEKP 318

Query: 498 YSCIFCPESFDRLDLLKDHVAIHINDGYFTCPTCKKRFPDFIQVKKHVRSFHSEKIYQCT 557
           Y C  C  +F     L +H  IH  +  F C  C K F    Q+  H R+    K + C+
Sbjct: 319 YGCNECGRAFSEKSNLINHQRIHTGEKPFECRECGKAFSRKSQLVTHHRTHTGTKPFGCS 378

Query: 558 ECDKAFCRPDKLRLHMLRHSDRKDFLCSTCGKQFKRKDKLREHMQRMHNPER-----EAK 612
           +C KAF    +L  H   H+  K + CS C K F+ +  L  H QR H  E+     +  
Sbjct: 379 DCRKAFFEKSELIRHQTIHTGEKPYECSECRKAFRERSSLINH-QRTHTGEKPHGCIQCG 437

Query: 613 KADRISRSKTFKPRITSTDYDSFTFKCRLCMMGFRRRGMLVNHLSKRHPDMKIEEVPE-- 670
           KA    +S     ++T T    F   C  C   F R+  LV H  + H   K  E  E  
Sbjct: 438 KAFS-QKSHLISHQMTHTGEKPFI--CSKCGKAFSRKSQLVRH-QRTHTGEKPYECSECG 493

Query: 671 ------LTLP----IIKPNRDYFCQYCDKVYKSASKRKAHILKNHPGAELPPSIRKLRPA 720
                 L+L     I    + Y C  C K +   S   +H  + H G E P    +   A
Sbjct: 494 KAFSEKLSLTNHQRIHTGEKPYVCSECGKAFCQKSHLISH-QRTHTG-EKPYECSECGKA 551

Query: 721 GPGEPDPMLSTHTQLTGTIATPPVCCPHCSKQYSSKTKMVQHIR 764
             GE    L+TH Q T T    P  C  C K +S K+++  H R
Sbjct: 552 F-GEKS-SLATH-QRTHT-GEKPYECRDCEKAFSQKSQLNTHQR 591



 Score =  124 bits (312), Expect = 3e-28
 Identities = 95/330 (28%), Positives = 135/330 (40%), Gaps = 34/330 (10%)

Query: 440 FKCLQCGKAFREKDKLDQHLRFHGREGNCPLTCDLCNKGFISSTSLESHMKLHSDQKTYS 499
           F C  CGK F +K +   H R H   G  P  C  C K F   + L SH + H+ +K Y 
Sbjct: 235 FGCGNCGKTFPQKSQFITHHRTH--TGEKPYNCSQCGKAFSQKSQLTSHQRTHTGEKPYE 292

Query: 500 CIFCPESFDRLDLLKDHVAIHINDGYFTCPTCKKRFPDFIQVKKHVRSFHSEKIYQCTEC 559
           C  C ++F R   L  H   H  +  + C  C + F +   +  H R    EK ++C EC
Sbjct: 293 CGECGKAFSRKSHLISHWRTHTGEKPYGCNECGRAFSEKSNLINHQRIHTGEKPFECREC 352

Query: 560 DKAFCRPDKLRLHMLRHSDRKDFLCSTCGKQFKRKDKLREHMQRMHNPER-----EAKKA 614
            KAF R  +L  H   H+  K F CS C K F  K +L  H Q +H  E+     E +KA
Sbjct: 353 GKAFSRKSQLVTHHRTHTGTKPFGCSDCRKAFFEKSELIRH-QTIHTGEKPYECSECRKA 411

Query: 615 DRISRSKTFKPRITSTDYDSFTFKCRLCMMGFRRRGMLVNHLSKRHPDMKIEEVPELTLP 674
            R  RS     + T T        C  C   F ++  L++H              ++T  
Sbjct: 412 FR-ERSSLINHQRTHT--GEKPHGCIQCGKAFSQKSHLISH--------------QMTHT 454

Query: 675 IIKPNRDYFCQYCDKVYKSASKRKAHILKNHPGAELPPSIRKLRPAGPGEPDPMLSTHTQ 734
             KP   + C  C K +   S+   H  + H G E P    +    G    + +  T+ Q
Sbjct: 455 GEKP---FICSKCGKAFSRKSQLVRH-QRTHTG-EKP---YECSECGKAFSEKLSLTNHQ 506

Query: 735 LTGTIATPPVCCPHCSKQYSSKTKMVQHIR 764
              T    P  C  C K +  K+ ++ H R
Sbjct: 507 RIHT-GEKPYVCSECGKAFCQKSHLISHQR 535



 Score =  120 bits (302), Expect = 5e-27
 Identities = 61/172 (35%), Positives = 87/172 (50%), Gaps = 3/172 (1%)

Query: 438 RPFKCLQCGKAFREKDKLDQHLRFHGREGNCPLTCDLCNKGFISSTSLESHMKLHSDQKT 497
           +P++C  C KAF +K +L+ H R H   G  P  C LC K F   + L  H++ H+ +K 
Sbjct: 569 KPYECRDCEKAFSQKSQLNTHQRIH--TGEKPYECSLCRKAFFEKSELIRHLRTHTGEKP 626

Query: 498 YSCIFCPESFDRLDLLKDHVAIHINDGYFTCPTCKKRFPDFIQVKKHVRSFHSEKIYQCT 557
           Y C  C ++F     L +H  IH  +  F C  C K F     +  H R+   EK Y C+
Sbjct: 627 YECNECRKAFREKSSLINHQRIHTGEKPFECSECGKAFSRKSHLIPHQRTHTGEKPYGCS 686

Query: 558 ECDKAFCRPDKLRLHMLRHSDRKDFLCSTCGKQFKRKDKLREHMQRMHNPER 609
           EC KAF +  +L  H   H+  K + C  CGK F +K +L  H QR H  ++
Sbjct: 687 ECRKAFSQKSQLVNHQRIHTGEKPYRCIECGKAFSQKSQLINH-QRTHTVKK 737



 Score =  108 bits (270), Expect = 3e-23
 Identities = 88/327 (26%), Positives = 126/327 (38%), Gaps = 28/327 (8%)

Query: 441 KCLQCGKAFREKDKLDQHLRFH-GREGNCPLTCDLCNKGFISSTSLESHMKLHSDQKTYS 499
           K   C K ++E  K  Q + +H  R G     C  C K F    SL  H   H     + 
Sbjct: 178 KYYDCDK-YKESYKKSQIIIYHRNRLGEKLYECSECRKRFSKKPSLIKHQSRHIRDIAFG 236

Query: 500 CIFCPESFDRLDLLKDHVAIHINDGYFTCPTCKKRFPDFIQVKKHVRSFHSEKIYQCTEC 559
           C  C ++F +      H   H  +  + C  C K F    Q+  H R+   EK Y+C EC
Sbjct: 237 CGNCGKTFPQKSQFITHHRTHTGEKPYNCSQCGKAFSQKSQLTSHQRTHTGEKPYECGEC 296

Query: 560 DKAFCRPDKLRLHMLRHSDRKDFLCSTCGKQFKRKDKLREHMQRMHNPER--EAKKADRI 617
            KAF R   L  H   H+  K + C+ CG+ F  K  L  H QR+H  E+  E ++  + 
Sbjct: 297 GKAFSRKSHLISHWRTHTGEKPYGCNECGRAFSEKSNLINH-QRIHTGEKPFECRECGKA 355

Query: 618 SRSKTFKPRITSTDYDSFTFKCRLCMMGFRRRGMLVNHLSKRHPDMKIEEVPELTLPIIK 677
              K+       T   +  F C  C   F  +  L+     RH  +   E P        
Sbjct: 356 FSRKSQLVTHHRTHTGTKPFGCSDCRKAFFEKSELI-----RHQTIHTGEKP-------- 402

Query: 678 PNRDYFCQYCDKVYKSASKRKAHILKNHPGAELPPSIRKLRPAGPGEPDPMLSTHTQLTG 737
               Y C  C K ++  S    H  + H G +    I+     G            Q+T 
Sbjct: 403 ----YECSECRKAFRERSSLINH-QRTHTGEKPHGCIQ----CGKAFSQKSHLISHQMTH 453

Query: 738 TIATPPVCCPHCSKQYSSKTKMVQHIR 764
           T    P  C  C K +S K+++V+H R
Sbjct: 454 T-GEKPFICSKCGKAFSRKSQLVRHQR 479



 Score = 78.2 bits (191), Expect = 4e-14
 Identities = 69/290 (23%), Positives = 105/290 (36%), Gaps = 30/290 (10%)

Query: 246 FVNQKIHDISEEERKVLREQ-----EKNWPCYECNRRFISSEQLQQHLNSHDEKLDVFSR 300
           F+  K       + +++R Q     EK + C EC + F     L  H   H  +      
Sbjct: 459 FICSKCGKAFSRKSQLVRHQRTHTGEKPYECSECGKAFSEKLSLTNHQRIHTGEKPYVCS 518

Query: 301 TRGRGRGRGKRRFGPGRRPGRPPKFIRLEITSENGEKSDDGTQDLLHFPTKE-QFDEAEP 359
             G+   +        R       +   E     GEKS   T    H   K  +  + E 
Sbjct: 519 ECGKAFCQKSHLISHQRTHTGEKPYECSECGKAFGEKSSLATHQRTHTGEKPYECRDCEK 578

Query: 360 ATLNGLDQPEQTTIPIPQLPQET---------QSSLEHEPETHTLHLQPQHEESVVPTQS 410
           A            I   + P E          +S L     THT              + 
Sbjct: 579 AFSQKSQLNTHQRIHTGEKPYECSLCRKAFFEKSELIRHLRTHT-------------GEK 625

Query: 411 TLTADDMRRAKRIRNAALQHLFIRKSFRPFKCLQCGKAFREKDKLDQHLRFHGREGNCPL 470
               ++ R+A R +++ + H  I    +PF+C +CGKAF  K  L  H R H   G  P 
Sbjct: 626 PYECNECRKAFREKSSLINHQRIHTGEKPFECSECGKAFSRKSHLIPHQRTH--TGEKPY 683

Query: 471 TCDLCNKGFISSTSLESHMKLHSDQKTYSCIFCPESFDRLDLLKDHVAIH 520
            C  C K F   + L +H ++H+ +K Y CI C ++F +   L +H   H
Sbjct: 684 GCSECRKAFSQKSQLVNHQRIHTGEKPYRCIECGKAFSQKSQLINHQRTH 733


>gi|188497653 zinc finger protein 84 [Homo sapiens]
          Length = 738

 Score =  149 bits (377), Expect = 1e-35
 Identities = 104/370 (28%), Positives = 153/370 (41%), Gaps = 38/370 (10%)

Query: 416 DMRRAKRIRNAALQHLFIRKSFRPFKCLQCGKAFREKDKLDQHLRFHGREGNCPLTCDLC 475
           D R+A   ++  ++H  I    +P++C +C KAFRE+  L  H R H   G  P  C  C
Sbjct: 379 DCRKAFFEKSELIRHQTIHTGEKPYECSECRKAFRERSSLINHQRTH--TGEKPHGCIQC 436

Query: 476 NKGFISSTSLESHMKLHSDQKTYSCIFCPESFDRLDLLKDHVAIHINDGYFTCPTCKKRF 535
            K F   + L SH   H+ +K + C  C ++F R   L  H   H  +  + C  C K F
Sbjct: 437 GKAFSQKSHLISHQMTHTGEKPFICSKCGKAFSRKSQLVRHQRTHTGEKPYECSECGKAF 496

Query: 536 PDFIQVKKHVRSFHSEKIYQCTECDKAFCRPDKLRLHMLRHSDRKDFLCSTCGKQFKRKD 595
            + + +  H R    EK Y C+EC KAFC+   L  H   H+  K + CS CGK F  K 
Sbjct: 497 SEKLSLTNHQRIHTGEKPYVCSECGKAFCQKSHLISHQRTHTGEKPYECSECGKAFGEKS 556

Query: 596 KLREHMQRMHNPER--EAKKADRISRSKTFKPRITSTDYDSFTFKCRLCMMGFRRRGMLV 653
            L  H QR H  E+  E +  ++    K+              ++C LC   F  +  L+
Sbjct: 557 SLATH-QRTHTGEKPYECRDCEKAFSQKSQLNTHQRIHTGEKPYECSLCRKAFFEKSELI 615

Query: 654 NHLSKRHPDMKIEEVPELTLP------------IIKPNRDYFCQYCDKVYKSASKRKAHI 701
            HL + H   K  E  E                I    + + C  C K +     RK+H+
Sbjct: 616 RHL-RTHTGEKPYECNECRKAFREKSSLINHQRIHTGEKPFECSECGKAF----SRKSHL 670

Query: 702 L---KNHPGAELPPSIRKLRPAGPGEPDPMLSTHTQLTG----TIATPPVCCPHCSKQYS 754
           +   + H G          +P G  E     S  +QL           P  C  C K +S
Sbjct: 671 IPHQRTHTGE---------KPYGCSECRKAFSQKSQLVNHQRIHTGEKPYRCIECGKAFS 721

Query: 755 SKTKMVQHIR 764
            K++++ H R
Sbjct: 722 QKSQLINHQR 731



 Score =  141 bits (355), Expect = 4e-33
 Identities = 95/333 (28%), Positives = 146/333 (43%), Gaps = 36/333 (10%)

Query: 438 RPFKCLQCGKAFREKDKLDQHLRFHGREGNCPLTCDLCNKGFISSTSLESHMKLHSDQKT 497
           +P+ C +CG+AF EK  L  H R H   G  P  C  C K F   + L +H + H+  K 
Sbjct: 317 KPYGCNECGRAFSEKSNLINHQRIH--TGEKPFECRECGKAFSRKSQLVTHHRTHTGTKP 374

Query: 498 YSCIFCPESFDRLDLLKDHVAIHINDGYFTCPTCKKRFPDFIQVKKHVRSFHSEKIYQCT 557
           + C  C ++F     L  H  IH  +  + C  C+K F +   +  H R+   EK + C 
Sbjct: 375 FGCSDCRKAFFEKSELIRHQTIHTGEKPYECSECRKAFRERSSLINHQRTHTGEKPHGCI 434

Query: 558 ECDKAFCRPDKLRLHMLRHSDRKDFLCSTCGKQFKRKDKLREHMQRMHNPEREAKKADRI 617
           +C KAF +   L  H + H+  K F+CS CGK F RK +L  H QR H  E+  + ++  
Sbjct: 435 QCGKAFSQKSHLISHQMTHTGEKPFICSKCGKAFSRKSQLVRH-QRTHTGEKPYECSE-- 491

Query: 618 SRSKTFKPRITSTDYDSF-----TFKCRLCMMGFRRRGMLVNHLSKRHPDMKIEEVPELT 672
              K F  +++ T++         + C  C   F ++  L++H  + H   K        
Sbjct: 492 -CGKAFSEKLSLTNHQRIHTGEKPYVCSECGKAFCQKSHLISH-QRTHTGEK-------- 541

Query: 673 LPIIKPNRDYFCQYCDKVYKSASKRKAHILKNHPGAELPPSIRKLRPAGPGEPDPMLSTH 732
                    Y C  C K +   S    H  + H G E P   R    A        L+TH
Sbjct: 542 --------PYECSECGKAFGEKSSLATH-QRTHTG-EKPYECRDCEKA--FSQKSQLNTH 589

Query: 733 TQL-TGTIATPPVCCPHCSKQYSSKTKMVQHIR 764
            ++ TG     P  C  C K +  K+++++H+R
Sbjct: 590 QRIHTG---EKPYECSLCRKAFFEKSELIRHLR 619



 Score =  140 bits (354), Expect = 5e-33
 Identities = 98/329 (29%), Positives = 140/329 (42%), Gaps = 28/329 (8%)

Query: 438 RPFKCLQCGKAFREKDKLDQHLRFHGREGNCPLTCDLCNKGFISSTSLESHMKLHSDQKT 497
           +PF C  C KAF EK +L +H   H   G  P  C  C K F   +SL +H + H+ +K 
Sbjct: 373 KPFGCSDCRKAFFEKSELIRHQTIH--TGEKPYECSECRKAFRERSSLINHQRTHTGEKP 430

Query: 498 YSCIFCPESFDRLDLLKDHVAIHINDGYFTCPTCKKRFPDFIQVKKHVRSFHSEKIYQCT 557
           + CI C ++F +   L  H   H  +  F C  C K F    Q+ +H R+   EK Y+C+
Sbjct: 431 HGCIQCGKAFSQKSHLISHQMTHTGEKPFICSKCGKAFSRKSQLVRHQRTHTGEKPYECS 490

Query: 558 ECDKAFCRPDKLRLHMLRHSDRKDFLCSTCGKQFKRKDKLREHMQRMHNPER--EAKKAD 615
           EC KAF     L  H   H+  K ++CS CGK F +K  L  H QR H  E+  E  +  
Sbjct: 491 ECGKAFSEKLSLTNHQRIHTGEKPYVCSECGKAFCQKSHLISH-QRTHTGEKPYECSECG 549

Query: 616 RISRSKTFKPRITSTDYDSFTFKCRLCMMGFRRRGMLVNHLSKRHPDMKIEEVPELTLPI 675
           +    K+       T      ++CR C   F ++  L  H                   I
Sbjct: 550 KAFGEKSSLATHQRTHTGEKPYECRDCEKAFSQKSQLNTHQR-----------------I 592

Query: 676 IKPNRDYFCQYCDKVYKSASKRKAHILKNHPGAELPPSIRKLRPAGPGEPDPMLSTHTQL 735
               + Y C  C K +   S+   H L+ H G E P    + R A   E   +++     
Sbjct: 593 HTGEKPYECSLCRKAFFEKSELIRH-LRTHTG-EKPYECNECRKAF-REKSSLINHQRIH 649

Query: 736 TGTIATPPVCCPHCSKQYSSKTKMVQHIR 764
           TG     P  C  C K +S K+ ++ H R
Sbjct: 650 TG---EKPFECSECGKAFSRKSHLIPHQR 675



 Score =  133 bits (335), Expect = 7e-31
 Identities = 108/344 (31%), Positives = 147/344 (42%), Gaps = 30/344 (8%)

Query: 438 RPFKCLQCGKAFREKDKLDQHLRFHGREGNCPLTCDLCNKGFISSTSLESHMKLHSDQKT 497
           +P+ C QCGKAF +K +L  H R H   G  P  C  C K F   + L SH + H+ +K 
Sbjct: 261 KPYNCSQCGKAFSQKSQLTSHQRTH--TGEKPYECGECGKAFSRKSHLISHWRTHTGEKP 318

Query: 498 YSCIFCPESFDRLDLLKDHVAIHINDGYFTCPTCKKRFPDFIQVKKHVRSFHSEKIYQCT 557
           Y C  C  +F     L +H  IH  +  F C  C K F    Q+  H R+    K + C+
Sbjct: 319 YGCNECGRAFSEKSNLINHQRIHTGEKPFECRECGKAFSRKSQLVTHHRTHTGTKPFGCS 378

Query: 558 ECDKAFCRPDKLRLHMLRHSDRKDFLCSTCGKQFKRKDKLREHMQRMHNPER-----EAK 612
           +C KAF    +L  H   H+  K + CS C K F+ +  L  H QR H  E+     +  
Sbjct: 379 DCRKAFFEKSELIRHQTIHTGEKPYECSECRKAFRERSSLINH-QRTHTGEKPHGCIQCG 437

Query: 613 KADRISRSKTFKPRITSTDYDSFTFKCRLCMMGFRRRGMLVNHLSKRHPDMKIEEVPE-- 670
           KA    +S     ++T T    F   C  C   F R+  LV H  + H   K  E  E  
Sbjct: 438 KAFS-QKSHLISHQMTHTGEKPFI--CSKCGKAFSRKSQLVRH-QRTHTGEKPYECSECG 493

Query: 671 ------LTLP----IIKPNRDYFCQYCDKVYKSASKRKAHILKNHPGAELPPSIRKLRPA 720
                 L+L     I    + Y C  C K +   S   +H  + H G E P    +   A
Sbjct: 494 KAFSEKLSLTNHQRIHTGEKPYVCSECGKAFCQKSHLISH-QRTHTG-EKPYECSECGKA 551

Query: 721 GPGEPDPMLSTHTQLTGTIATPPVCCPHCSKQYSSKTKMVQHIR 764
             GE    L+TH Q T T    P  C  C K +S K+++  H R
Sbjct: 552 F-GEKS-SLATH-QRTHT-GEKPYECRDCEKAFSQKSQLNTHQR 591



 Score =  124 bits (312), Expect = 3e-28
 Identities = 95/330 (28%), Positives = 135/330 (40%), Gaps = 34/330 (10%)

Query: 440 FKCLQCGKAFREKDKLDQHLRFHGREGNCPLTCDLCNKGFISSTSLESHMKLHSDQKTYS 499
           F C  CGK F +K +   H R H   G  P  C  C K F   + L SH + H+ +K Y 
Sbjct: 235 FGCGNCGKTFPQKSQFITHHRTH--TGEKPYNCSQCGKAFSQKSQLTSHQRTHTGEKPYE 292

Query: 500 CIFCPESFDRLDLLKDHVAIHINDGYFTCPTCKKRFPDFIQVKKHVRSFHSEKIYQCTEC 559
           C  C ++F R   L  H   H  +  + C  C + F +   +  H R    EK ++C EC
Sbjct: 293 CGECGKAFSRKSHLISHWRTHTGEKPYGCNECGRAFSEKSNLINHQRIHTGEKPFECREC 352

Query: 560 DKAFCRPDKLRLHMLRHSDRKDFLCSTCGKQFKRKDKLREHMQRMHNPER-----EAKKA 614
            KAF R  +L  H   H+  K F CS C K F  K +L  H Q +H  E+     E +KA
Sbjct: 353 GKAFSRKSQLVTHHRTHTGTKPFGCSDCRKAFFEKSELIRH-QTIHTGEKPYECSECRKA 411

Query: 615 DRISRSKTFKPRITSTDYDSFTFKCRLCMMGFRRRGMLVNHLSKRHPDMKIEEVPELTLP 674
            R  RS     + T T        C  C   F ++  L++H              ++T  
Sbjct: 412 FR-ERSSLINHQRTHT--GEKPHGCIQCGKAFSQKSHLISH--------------QMTHT 454

Query: 675 IIKPNRDYFCQYCDKVYKSASKRKAHILKNHPGAELPPSIRKLRPAGPGEPDPMLSTHTQ 734
             KP   + C  C K +   S+   H  + H G E P    +    G    + +  T+ Q
Sbjct: 455 GEKP---FICSKCGKAFSRKSQLVRH-QRTHTG-EKP---YECSECGKAFSEKLSLTNHQ 506

Query: 735 LTGTIATPPVCCPHCSKQYSSKTKMVQHIR 764
              T    P  C  C K +  K+ ++ H R
Sbjct: 507 RIHT-GEKPYVCSECGKAFCQKSHLISHQR 535



 Score =  120 bits (302), Expect = 5e-27
 Identities = 61/172 (35%), Positives = 87/172 (50%), Gaps = 3/172 (1%)

Query: 438 RPFKCLQCGKAFREKDKLDQHLRFHGREGNCPLTCDLCNKGFISSTSLESHMKLHSDQKT 497
           +P++C  C KAF +K +L+ H R H   G  P  C LC K F   + L  H++ H+ +K 
Sbjct: 569 KPYECRDCEKAFSQKSQLNTHQRIH--TGEKPYECSLCRKAFFEKSELIRHLRTHTGEKP 626

Query: 498 YSCIFCPESFDRLDLLKDHVAIHINDGYFTCPTCKKRFPDFIQVKKHVRSFHSEKIYQCT 557
           Y C  C ++F     L +H  IH  +  F C  C K F     +  H R+   EK Y C+
Sbjct: 627 YECNECRKAFREKSSLINHQRIHTGEKPFECSECGKAFSRKSHLIPHQRTHTGEKPYGCS 686

Query: 558 ECDKAFCRPDKLRLHMLRHSDRKDFLCSTCGKQFKRKDKLREHMQRMHNPER 609
           EC KAF +  +L  H   H+  K + C  CGK F +K +L  H QR H  ++
Sbjct: 687 ECRKAFSQKSQLVNHQRIHTGEKPYRCIECGKAFSQKSQLINH-QRTHTVKK 737



 Score =  108 bits (270), Expect = 3e-23
 Identities = 88/327 (26%), Positives = 126/327 (38%), Gaps = 28/327 (8%)

Query: 441 KCLQCGKAFREKDKLDQHLRFH-GREGNCPLTCDLCNKGFISSTSLESHMKLHSDQKTYS 499
           K   C K ++E  K  Q + +H  R G     C  C K F    SL  H   H     + 
Sbjct: 178 KYYDCDK-YKESYKKSQIIIYHRNRLGEKLYECSECRKRFSKKPSLIKHQSRHIRDIAFG 236

Query: 500 CIFCPESFDRLDLLKDHVAIHINDGYFTCPTCKKRFPDFIQVKKHVRSFHSEKIYQCTEC 559
           C  C ++F +      H   H  +  + C  C K F    Q+  H R+   EK Y+C EC
Sbjct: 237 CGNCGKTFPQKSQFITHHRTHTGEKPYNCSQCGKAFSQKSQLTSHQRTHTGEKPYECGEC 296

Query: 560 DKAFCRPDKLRLHMLRHSDRKDFLCSTCGKQFKRKDKLREHMQRMHNPER--EAKKADRI 617
            KAF R   L  H   H+  K + C+ CG+ F  K  L  H QR+H  E+  E ++  + 
Sbjct: 297 GKAFSRKSHLISHWRTHTGEKPYGCNECGRAFSEKSNLINH-QRIHTGEKPFECRECGKA 355

Query: 618 SRSKTFKPRITSTDYDSFTFKCRLCMMGFRRRGMLVNHLSKRHPDMKIEEVPELTLPIIK 677
              K+       T   +  F C  C   F  +  L+     RH  +   E P        
Sbjct: 356 FSRKSQLVTHHRTHTGTKPFGCSDCRKAFFEKSELI-----RHQTIHTGEKP-------- 402

Query: 678 PNRDYFCQYCDKVYKSASKRKAHILKNHPGAELPPSIRKLRPAGPGEPDPMLSTHTQLTG 737
               Y C  C K ++  S    H  + H G +    I+     G            Q+T 
Sbjct: 403 ----YECSECRKAFRERSSLINH-QRTHTGEKPHGCIQ----CGKAFSQKSHLISHQMTH 453

Query: 738 TIATPPVCCPHCSKQYSSKTKMVQHIR 764
           T    P  C  C K +S K+++V+H R
Sbjct: 454 T-GEKPFICSKCGKAFSRKSQLVRHQR 479



 Score = 78.2 bits (191), Expect = 4e-14
 Identities = 69/290 (23%), Positives = 105/290 (36%), Gaps = 30/290 (10%)

Query: 246 FVNQKIHDISEEERKVLREQ-----EKNWPCYECNRRFISSEQLQQHLNSHDEKLDVFSR 300
           F+  K       + +++R Q     EK + C EC + F     L  H   H  +      
Sbjct: 459 FICSKCGKAFSRKSQLVRHQRTHTGEKPYECSECGKAFSEKLSLTNHQRIHTGEKPYVCS 518

Query: 301 TRGRGRGRGKRRFGPGRRPGRPPKFIRLEITSENGEKSDDGTQDLLHFPTKE-QFDEAEP 359
             G+   +        R       +   E     GEKS   T    H   K  +  + E 
Sbjct: 519 ECGKAFCQKSHLISHQRTHTGEKPYECSECGKAFGEKSSLATHQRTHTGEKPYECRDCEK 578

Query: 360 ATLNGLDQPEQTTIPIPQLPQET---------QSSLEHEPETHTLHLQPQHEESVVPTQS 410
           A            I   + P E          +S L     THT              + 
Sbjct: 579 AFSQKSQLNTHQRIHTGEKPYECSLCRKAFFEKSELIRHLRTHT-------------GEK 625

Query: 411 TLTADDMRRAKRIRNAALQHLFIRKSFRPFKCLQCGKAFREKDKLDQHLRFHGREGNCPL 470
               ++ R+A R +++ + H  I    +PF+C +CGKAF  K  L  H R H   G  P 
Sbjct: 626 PYECNECRKAFREKSSLINHQRIHTGEKPFECSECGKAFSRKSHLIPHQRTH--TGEKPY 683

Query: 471 TCDLCNKGFISSTSLESHMKLHSDQKTYSCIFCPESFDRLDLLKDHVAIH 520
            C  C K F   + L +H ++H+ +K Y CI C ++F +   L +H   H
Sbjct: 684 GCSECRKAFSQKSQLVNHQRIHTGEKPYRCIECGKAFSQKSQLINHQRTH 733


>gi|197313746 zinc finger protein 502 [Homo sapiens]
          Length = 544

 Score =  147 bits (371), Expect = 5e-35
 Identities = 126/448 (28%), Positives = 176/448 (39%), Gaps = 51/448 (11%)

Query: 229 VEPKQELKVWYAASYAEFVNQKIHDISEEER-KVLREQEKNWPCYECNRRFISSEQLQQH 287
           V  ++ L  W      E  N + +DIS++ +   L  Q+K+W C EC + F  S  L QH
Sbjct: 120 VSTEESLHQW------ETSNIQTNDISDQSKCPTLCTQKKSWKCNECGKTFTQSSSLTQH 173

Query: 288 LNSHDEKLDVFSRTRGRGRGRGK-----RRFGPGRRPG---------RPPKFIRLEITSE 333
             +H  +        G+   R       +R   G +P          R   F+       
Sbjct: 174 QRTHTGERPYTCEECGKAFSRSSFLVQHQRIHTGVKPYGCEQCGKTFRCRSFLTQHQRIH 233

Query: 334 NGEKSDDGTQDLLHFPTKEQFDEAEPATLNGLDQPEQTTIPIPQLPQE-TQSSLEHEPET 392
            GEK           P K   +E   +  N     E   I   + P +  +        T
Sbjct: 234 TGEK-----------PYK--CNECGNSFRNHSHLTEHQRIHTGEKPYKCNRCGKAFNQNT 280

Query: 393 HTLHLQPQHEESVVPTQSTLTADDMRRAKRIRNAALQHLFIRKSFRPFKCLQCGKAFREK 452
           H +H Q  H       +      +   + R  +   QH  I    +P KC +CGK F+ K
Sbjct: 281 HLIHHQRIHTG-----EKPYICSECGSSFRKHSNLTQHQRIHTGEKPHKCDECGKTFQTK 335

Query: 453 DKLDQHLRFHGREGNCPLTCDLCNKGFISSTSLESHMKLHSDQKTYSCIFCPESFDRLDL 512
             L QH R H   G  P  C  C K F  S SL  H ++H+ +K Y C  C ++F +   
Sbjct: 336 ANLSQHQRIHS--GEKPYKCKECGKAFCQSPSLIKHQRIHTGEKPYKCKECGKAFTQSTP 393

Query: 513 LKDHVAIHINDGYFTCPTCKKRFPDFIQVKKHVRSFHSEKIYQCTECDKAFCRPDKLRLH 572
           L  H  IH  +  + C  C K F   I + +H RS   EK Y+C EC K F +   L  H
Sbjct: 394 LTKHQRIHTGERPYKCSECGKAFIQSICLIRHQRSHTGEKPYKCNECGKGFNQNTCLTQH 453

Query: 573 MLRHSDRKDFLCSTCGKQFKRKDKLREHMQRMHNPEREAKKADRISRSKTF-KPRITSTD 631
           M  H+  K + C  CGK F     L EH  R H  E+  K ++     KTF K    S  
Sbjct: 454 MRIHTGEKPYKCKECGKAFAHSSSLTEH-HRTHTGEKLYKCSE---CEKTFRKYAHLSEH 509

Query: 632 YDSFT----FKCRLCMMGFRRRGMLVNH 655
           Y   T    ++C  C   FR   +L  H
Sbjct: 510 YRIHTGEKPYECIECGKFFRHSSVLFRH 537



 Score =  141 bits (355), Expect = 4e-33
 Identities = 91/294 (30%), Positives = 126/294 (42%), Gaps = 29/294 (9%)

Query: 422 RIRNAALQHLFIRKSFRPFKCLQCGKAFREKDKLDQHLRFHGREGNCPLTCDLCNKGFIS 481
           R R+   QH  I    +P+KC +CG +FR    L +H R H   G  P  C+ C K F  
Sbjct: 221 RCRSFLTQHQRIHTGEKPYKCNECGNSFRNHSHLTEHQRIH--TGEKPYKCNRCGKAFNQ 278

Query: 482 STSLESHMKLHSDQKTYSCIFCPESFDRLDLLKDHVAIHINDGYFTCPTCKKRFPDFIQV 541
           +T L  H ++H+ +K Y C  C  SF +   L  H  IH  +    C  C K F     +
Sbjct: 279 NTHLIHHQRIHTGEKPYICSECGSSFRKHSNLTQHQRIHTGEKPHKCDECGKTFQTKANL 338

Query: 542 KKHVRSFHSEKIYQCTECDKAFCRPDKLRLHMLRHSDRKDFLCSTCGKQFKRKDKLREHM 601
            +H R    EK Y+C EC KAFC+   L  H   H+  K + C  CGK F +   L +H 
Sbjct: 339 SQHQRIHSGEKPYKCKECGKAFCQSPSLIKHQRIHTGEKPYKCKECGKAFTQSTPLTKH- 397

Query: 602 QRMHNPEREAKKADRISRSKTFKPRITSTDYD-SFT----FKCRLCMMGFRRRGMLVNHL 656
           QR+H  ER  K ++     K F   I    +  S T    +KC  C  GF +   L  H+
Sbjct: 398 QRIHTGERPYKCSE---CGKAFIQSICLIRHQRSHTGEKPYKCNECGKGFNQNTCLTQHM 454

Query: 657 SKRHPDMKIEEVPELTLPIIKPNRDYFCQYCDKVYKSASKRKAHILKNHPGAEL 710
                             I    + Y C+ C K +  +S    H  + H G +L
Sbjct: 455 R-----------------IHTGEKPYKCKECGKAFAHSSSLTEH-HRTHTGEKL 490



 Score =  133 bits (335), Expect = 7e-31
 Identities = 98/346 (28%), Positives = 149/346 (43%), Gaps = 34/346 (9%)

Query: 438 RPFKCLQCGKAFREKDKLDQHLRFHGREGNCPLTCDLCNKGFISSTSLESHMKLHSDQKT 497
           + +KC +CGK F +   L QH R H   G  P TC+ C K F  S+ L  H ++H+  K 
Sbjct: 153 KSWKCNECGKTFTQSSSLTQHQRTH--TGERPYTCEECGKAFSRSSFLVQHQRIHTGVKP 210

Query: 498 YSCIFCPESFDRLDLLKDHVAIHINDGYFTCPTCKKRFPDFIQVKKHVRSFHSEKIYQCT 557
           Y C  C ++F     L  H  IH  +  + C  C   F +   + +H R    EK Y+C 
Sbjct: 211 YGCEQCGKTFRCRSFLTQHQRIHTGEKPYKCNECGNSFRNHSHLTEHQRIHTGEKPYKCN 270

Query: 558 ECDKAFCRPDKLRLHMLRHSDRKDFLCSTCGKQFKRKDKLREHMQRMHNPEREAKKADRI 617
            C KAF +   L  H   H+  K ++CS CG  F++   L +H QR+H  E+   K D  
Sbjct: 271 RCGKAFNQNTHLIHHQRIHTGEKPYICSECGSSFRKHSNLTQH-QRIHTGEK-PHKCDEC 328

Query: 618 SRSKTFKPRITSTDYDSF-----TFKCRLCMMGFRRRGMLVNHLSKRHPDMKIEEVPEL- 671
              KTF+ +   + +         +KC+ C   F +   L+ H  + H   K  +  E  
Sbjct: 329 --GKTFQTKANLSQHQRIHSGEKPYKCKECGKAFCQSPSLIKH-QRIHTGEKPYKCKECG 385

Query: 672 -----TLPIIK------PNRDYFCQYCDKVYKSASKRKAHILKNHPGAELPPSIRKLRPA 720
                + P+ K        R Y C  C K +  +     H  ++H G E P    K    
Sbjct: 386 KAFTQSTPLTKHQRIHTGERPYKCSECGKAFIQSICLIRH-QRSHTG-EKP---YKCNEC 440

Query: 721 GPG-EPDPMLSTHTQL-TGTIATPPVCCPHCSKQYSSKTKMVQHIR 764
           G G   +  L+ H ++ TG     P  C  C K ++  + + +H R
Sbjct: 441 GKGFNQNTCLTQHMRIHTG---EKPYKCKECGKAFAHSSSLTEHHR 483



 Score =  123 bits (309), Expect = 8e-28
 Identities = 61/179 (34%), Positives = 91/179 (50%), Gaps = 3/179 (1%)

Query: 428 LQHLFIRKSFRPFKCLQCGKAFREKDKLDQHLRFHGREGNCPLTCDLCNKGFISSTSLES 487
           ++H  I    +P+KC +CGKAF +   L +H R H   G  P  C  C K FI S  L  
Sbjct: 367 IKHQRIHTGEKPYKCKECGKAFTQSTPLTKHQRIH--TGERPYKCSECGKAFIQSICLIR 424

Query: 488 HMKLHSDQKTYSCIFCPESFDRLDLLKDHVAIHINDGYFTCPTCKKRFPDFIQVKKHVRS 547
           H + H+ +K Y C  C + F++   L  H+ IH  +  + C  C K F     + +H R+
Sbjct: 425 HQRSHTGEKPYKCNECGKGFNQNTCLTQHMRIHTGEKPYKCKECGKAFAHSSSLTEHHRT 484

Query: 548 FHSEKIYQCTECDKAFCRPDKLRLHMLRHSDRKDFLCSTCGKQFKRKDKLREHMQRMHN 606
              EK+Y+C+EC+K F +   L  H   H+  K + C  CGK F+    L  H Q++H+
Sbjct: 485 HTGEKLYKCSECEKTFRKYAHLSEHYRIHTGEKPYECIECGKFFRHSSVLFRH-QKLHS 542



 Score = 76.6 bits (187), Expect = 1e-13
 Identities = 67/277 (24%), Positives = 105/277 (37%), Gaps = 28/277 (10%)

Query: 491 LHSDQKTYSCIFCPESFDRLDLLKDHVAIHINDGYFTCPTCKKRFPDFIQVKKHVRSFHS 550
           L + +K++ C  C ++F +   L  H   H  +  +TC  C K F     + +H R    
Sbjct: 148 LCTQKKSWKCNECGKTFTQSSSLTQHQRTHTGERPYTCEECGKAFSRSSFLVQHQRIHTG 207

Query: 551 EKIYQCTECDKAFCRPDKLRLHMLRHSDRKDFLCSTCGKQFKRKDKLREHMQRMHNPERE 610
            K Y C +C K F     L  H   H+  K + C+ CG  F+    L EH QR+H  E+ 
Sbjct: 208 VKPYGCEQCGKTFRCRSFLTQHQRIHTGEKPYKCNECGNSFRNHSHLTEH-QRIHTGEKP 266

Query: 611 AK--KADRISRSKTFKPRITSTDYDSFTFKCRLCMMGFRRRGMLVNHLSKRHPDMKIEEV 668
            K  +  +     T              + C  C   FR+   L  H      +      
Sbjct: 267 YKCNRCGKAFNQNTHLIHHQRIHTGEKPYICSECGSSFRKHSNLTQHQRIHTGE------ 320

Query: 669 PELTLPIIKPNRDYFCQYCDKVYKSASKRKAHILKNHPGAELPPSIRKLRPAGPGEPDPM 728
                   KP++   C  C K +++ +    H  + H G E P   ++   A      P 
Sbjct: 321 --------KPHK---CDECGKTFQTKANLSQH-QRIHSG-EKPYKCKECGKAFC--QSPS 365

Query: 729 LSTHTQL-TGTIATPPVCCPHCSKQYSSKTKMVQHIR 764
           L  H ++ TG     P  C  C K ++  T + +H R
Sbjct: 366 LIKHQRIHTG---EKPYKCKECGKAFTQSTPLTKHQR 399



 Score = 67.4 bits (163), Expect = 7e-11
 Identities = 33/95 (34%), Positives = 45/95 (47%), Gaps = 2/95 (2%)

Query: 429 QHLFIRKSFRPFKCLQCGKAFREKDKLDQHLRFHGREGNCPLTCDLCNKGFISSTSLESH 488
           QH+ I    +P+KC +CGKAF     L +H R H   G     C  C K F     L  H
Sbjct: 452 QHMRIHTGEKPYKCKECGKAFAHSSSLTEHHRTH--TGEKLYKCSECEKTFRKYAHLSEH 509

Query: 489 MKLHSDQKTYSCIFCPESFDRLDLLKDHVAIHIND 523
            ++H+ +K Y CI C + F    +L  H  +H  D
Sbjct: 510 YRIHTGEKPYECIECGKFFRHSSVLFRHQKLHSGD 544


>gi|197313744 zinc finger protein 502 [Homo sapiens]
          Length = 544

 Score =  147 bits (371), Expect = 5e-35
 Identities = 126/448 (28%), Positives = 176/448 (39%), Gaps = 51/448 (11%)

Query: 229 VEPKQELKVWYAASYAEFVNQKIHDISEEER-KVLREQEKNWPCYECNRRFISSEQLQQH 287
           V  ++ L  W      E  N + +DIS++ +   L  Q+K+W C EC + F  S  L QH
Sbjct: 120 VSTEESLHQW------ETSNIQTNDISDQSKCPTLCTQKKSWKCNECGKTFTQSSSLTQH 173

Query: 288 LNSHDEKLDVFSRTRGRGRGRGK-----RRFGPGRRPG---------RPPKFIRLEITSE 333
             +H  +        G+   R       +R   G +P          R   F+       
Sbjct: 174 QRTHTGERPYTCEECGKAFSRSSFLVQHQRIHTGVKPYGCEQCGKTFRCRSFLTQHQRIH 233

Query: 334 NGEKSDDGTQDLLHFPTKEQFDEAEPATLNGLDQPEQTTIPIPQLPQE-TQSSLEHEPET 392
            GEK           P K   +E   +  N     E   I   + P +  +        T
Sbjct: 234 TGEK-----------PYK--CNECGNSFRNHSHLTEHQRIHTGEKPYKCNRCGKAFNQNT 280

Query: 393 HTLHLQPQHEESVVPTQSTLTADDMRRAKRIRNAALQHLFIRKSFRPFKCLQCGKAFREK 452
           H +H Q  H       +      +   + R  +   QH  I    +P KC +CGK F+ K
Sbjct: 281 HLIHHQRIHTG-----EKPYICSECGSSFRKHSNLTQHQRIHTGEKPHKCDECGKTFQTK 335

Query: 453 DKLDQHLRFHGREGNCPLTCDLCNKGFISSTSLESHMKLHSDQKTYSCIFCPESFDRLDL 512
             L QH R H   G  P  C  C K F  S SL  H ++H+ +K Y C  C ++F +   
Sbjct: 336 ANLSQHQRIHS--GEKPYKCKECGKAFCQSPSLIKHQRIHTGEKPYKCKECGKAFTQSTP 393

Query: 513 LKDHVAIHINDGYFTCPTCKKRFPDFIQVKKHVRSFHSEKIYQCTECDKAFCRPDKLRLH 572
           L  H  IH  +  + C  C K F   I + +H RS   EK Y+C EC K F +   L  H
Sbjct: 394 LTKHQRIHTGERPYKCSECGKAFIQSICLIRHQRSHTGEKPYKCNECGKGFNQNTCLTQH 453

Query: 573 MLRHSDRKDFLCSTCGKQFKRKDKLREHMQRMHNPEREAKKADRISRSKTF-KPRITSTD 631
           M  H+  K + C  CGK F     L EH  R H  E+  K ++     KTF K    S  
Sbjct: 454 MRIHTGEKPYKCKECGKAFAHSSSLTEH-HRTHTGEKLYKCSE---CEKTFRKYAHLSEH 509

Query: 632 YDSFT----FKCRLCMMGFRRRGMLVNH 655
           Y   T    ++C  C   FR   +L  H
Sbjct: 510 YRIHTGEKPYECIECGKFFRHSSVLFRH 537



 Score =  141 bits (355), Expect = 4e-33
 Identities = 91/294 (30%), Positives = 126/294 (42%), Gaps = 29/294 (9%)

Query: 422 RIRNAALQHLFIRKSFRPFKCLQCGKAFREKDKLDQHLRFHGREGNCPLTCDLCNKGFIS 481
           R R+   QH  I    +P+KC +CG +FR    L +H R H   G  P  C+ C K F  
Sbjct: 221 RCRSFLTQHQRIHTGEKPYKCNECGNSFRNHSHLTEHQRIH--TGEKPYKCNRCGKAFNQ 278

Query: 482 STSLESHMKLHSDQKTYSCIFCPESFDRLDLLKDHVAIHINDGYFTCPTCKKRFPDFIQV 541
           +T L  H ++H+ +K Y C  C  SF +   L  H  IH  +    C  C K F     +
Sbjct: 279 NTHLIHHQRIHTGEKPYICSECGSSFRKHSNLTQHQRIHTGEKPHKCDECGKTFQTKANL 338

Query: 542 KKHVRSFHSEKIYQCTECDKAFCRPDKLRLHMLRHSDRKDFLCSTCGKQFKRKDKLREHM 601
            +H R    EK Y+C EC KAFC+   L  H   H+  K + C  CGK F +   L +H 
Sbjct: 339 SQHQRIHSGEKPYKCKECGKAFCQSPSLIKHQRIHTGEKPYKCKECGKAFTQSTPLTKH- 397

Query: 602 QRMHNPEREAKKADRISRSKTFKPRITSTDYD-SFT----FKCRLCMMGFRRRGMLVNHL 656
           QR+H  ER  K ++     K F   I    +  S T    +KC  C  GF +   L  H+
Sbjct: 398 QRIHTGERPYKCSE---CGKAFIQSICLIRHQRSHTGEKPYKCNECGKGFNQNTCLTQHM 454

Query: 657 SKRHPDMKIEEVPELTLPIIKPNRDYFCQYCDKVYKSASKRKAHILKNHPGAEL 710
                             I    + Y C+ C K +  +S    H  + H G +L
Sbjct: 455 R-----------------IHTGEKPYKCKECGKAFAHSSSLTEH-HRTHTGEKL 490



 Score =  133 bits (335), Expect = 7e-31
 Identities = 98/346 (28%), Positives = 149/346 (43%), Gaps = 34/346 (9%)

Query: 438 RPFKCLQCGKAFREKDKLDQHLRFHGREGNCPLTCDLCNKGFISSTSLESHMKLHSDQKT 497
           + +KC +CGK F +   L QH R H   G  P TC+ C K F  S+ L  H ++H+  K 
Sbjct: 153 KSWKCNECGKTFTQSSSLTQHQRTH--TGERPYTCEECGKAFSRSSFLVQHQRIHTGVKP 210

Query: 498 YSCIFCPESFDRLDLLKDHVAIHINDGYFTCPTCKKRFPDFIQVKKHVRSFHSEKIYQCT 557
           Y C  C ++F     L  H  IH  +  + C  C   F +   + +H R    EK Y+C 
Sbjct: 211 YGCEQCGKTFRCRSFLTQHQRIHTGEKPYKCNECGNSFRNHSHLTEHQRIHTGEKPYKCN 270

Query: 558 ECDKAFCRPDKLRLHMLRHSDRKDFLCSTCGKQFKRKDKLREHMQRMHNPEREAKKADRI 617
            C KAF +   L  H   H+  K ++CS CG  F++   L +H QR+H  E+   K D  
Sbjct: 271 RCGKAFNQNTHLIHHQRIHTGEKPYICSECGSSFRKHSNLTQH-QRIHTGEK-PHKCDEC 328

Query: 618 SRSKTFKPRITSTDYDSF-----TFKCRLCMMGFRRRGMLVNHLSKRHPDMKIEEVPEL- 671
              KTF+ +   + +         +KC+ C   F +   L+ H  + H   K  +  E  
Sbjct: 329 --GKTFQTKANLSQHQRIHSGEKPYKCKECGKAFCQSPSLIKH-QRIHTGEKPYKCKECG 385

Query: 672 -----TLPIIK------PNRDYFCQYCDKVYKSASKRKAHILKNHPGAELPPSIRKLRPA 720
                + P+ K        R Y C  C K +  +     H  ++H G E P    K    
Sbjct: 386 KAFTQSTPLTKHQRIHTGERPYKCSECGKAFIQSICLIRH-QRSHTG-EKP---YKCNEC 440

Query: 721 GPG-EPDPMLSTHTQL-TGTIATPPVCCPHCSKQYSSKTKMVQHIR 764
           G G   +  L+ H ++ TG     P  C  C K ++  + + +H R
Sbjct: 441 GKGFNQNTCLTQHMRIHTG---EKPYKCKECGKAFAHSSSLTEHHR 483



 Score =  123 bits (309), Expect = 8e-28
 Identities = 61/179 (34%), Positives = 91/179 (50%), Gaps = 3/179 (1%)

Query: 428 LQHLFIRKSFRPFKCLQCGKAFREKDKLDQHLRFHGREGNCPLTCDLCNKGFISSTSLES 487
           ++H  I    +P+KC +CGKAF +   L +H R H   G  P  C  C K FI S  L  
Sbjct: 367 IKHQRIHTGEKPYKCKECGKAFTQSTPLTKHQRIH--TGERPYKCSECGKAFIQSICLIR 424

Query: 488 HMKLHSDQKTYSCIFCPESFDRLDLLKDHVAIHINDGYFTCPTCKKRFPDFIQVKKHVRS 547
           H + H+ +K Y C  C + F++   L  H+ IH  +  + C  C K F     + +H R+
Sbjct: 425 HQRSHTGEKPYKCNECGKGFNQNTCLTQHMRIHTGEKPYKCKECGKAFAHSSSLTEHHRT 484

Query: 548 FHSEKIYQCTECDKAFCRPDKLRLHMLRHSDRKDFLCSTCGKQFKRKDKLREHMQRMHN 606
              EK+Y+C+EC+K F +   L  H   H+  K + C  CGK F+    L  H Q++H+
Sbjct: 485 HTGEKLYKCSECEKTFRKYAHLSEHYRIHTGEKPYECIECGKFFRHSSVLFRH-QKLHS 542



 Score = 76.6 bits (187), Expect = 1e-13
 Identities = 67/277 (24%), Positives = 105/277 (37%), Gaps = 28/277 (10%)

Query: 491 LHSDQKTYSCIFCPESFDRLDLLKDHVAIHINDGYFTCPTCKKRFPDFIQVKKHVRSFHS 550
           L + +K++ C  C ++F +   L  H   H  +  +TC  C K F     + +H R    
Sbjct: 148 LCTQKKSWKCNECGKTFTQSSSLTQHQRTHTGERPYTCEECGKAFSRSSFLVQHQRIHTG 207

Query: 551 EKIYQCTECDKAFCRPDKLRLHMLRHSDRKDFLCSTCGKQFKRKDKLREHMQRMHNPERE 610
            K Y C +C K F     L  H   H+  K + C+ CG  F+    L EH QR+H  E+ 
Sbjct: 208 VKPYGCEQCGKTFRCRSFLTQHQRIHTGEKPYKCNECGNSFRNHSHLTEH-QRIHTGEKP 266

Query: 611 AK--KADRISRSKTFKPRITSTDYDSFTFKCRLCMMGFRRRGMLVNHLSKRHPDMKIEEV 668
            K  +  +     T              + C  C   FR+   L  H      +      
Sbjct: 267 YKCNRCGKAFNQNTHLIHHQRIHTGEKPYICSECGSSFRKHSNLTQHQRIHTGE------ 320

Query: 669 PELTLPIIKPNRDYFCQYCDKVYKSASKRKAHILKNHPGAELPPSIRKLRPAGPGEPDPM 728
                   KP++   C  C K +++ +    H  + H G E P   ++   A      P 
Sbjct: 321 --------KPHK---CDECGKTFQTKANLSQH-QRIHSG-EKPYKCKECGKAFC--QSPS 365

Query: 729 LSTHTQL-TGTIATPPVCCPHCSKQYSSKTKMVQHIR 764
           L  H ++ TG     P  C  C K ++  T + +H R
Sbjct: 366 LIKHQRIHTG---EKPYKCKECGKAFTQSTPLTKHQR 399



 Score = 67.4 bits (163), Expect = 7e-11
 Identities = 33/95 (34%), Positives = 45/95 (47%), Gaps = 2/95 (2%)

Query: 429 QHLFIRKSFRPFKCLQCGKAFREKDKLDQHLRFHGREGNCPLTCDLCNKGFISSTSLESH 488
           QH+ I    +P+KC +CGKAF     L +H R H   G     C  C K F     L  H
Sbjct: 452 QHMRIHTGEKPYKCKECGKAFAHSSSLTEHHRTH--TGEKLYKCSECEKTFRKYAHLSEH 509

Query: 489 MKLHSDQKTYSCIFCPESFDRLDLLKDHVAIHIND 523
            ++H+ +K Y CI C + F    +L  H  +H  D
Sbjct: 510 YRIHTGEKPYECIECGKFFRHSSVLFRHQKLHSGD 544


>gi|197313742 zinc finger protein 502 [Homo sapiens]
          Length = 544

 Score =  147 bits (371), Expect = 5e-35
 Identities = 126/448 (28%), Positives = 176/448 (39%), Gaps = 51/448 (11%)

Query: 229 VEPKQELKVWYAASYAEFVNQKIHDISEEER-KVLREQEKNWPCYECNRRFISSEQLQQH 287
           V  ++ L  W      E  N + +DIS++ +   L  Q+K+W C EC + F  S  L QH
Sbjct: 120 VSTEESLHQW------ETSNIQTNDISDQSKCPTLCTQKKSWKCNECGKTFTQSSSLTQH 173

Query: 288 LNSHDEKLDVFSRTRGRGRGRGK-----RRFGPGRRPG---------RPPKFIRLEITSE 333
             +H  +        G+   R       +R   G +P          R   F+       
Sbjct: 174 QRTHTGERPYTCEECGKAFSRSSFLVQHQRIHTGVKPYGCEQCGKTFRCRSFLTQHQRIH 233

Query: 334 NGEKSDDGTQDLLHFPTKEQFDEAEPATLNGLDQPEQTTIPIPQLPQE-TQSSLEHEPET 392
            GEK           P K   +E   +  N     E   I   + P +  +        T
Sbjct: 234 TGEK-----------PYK--CNECGNSFRNHSHLTEHQRIHTGEKPYKCNRCGKAFNQNT 280

Query: 393 HTLHLQPQHEESVVPTQSTLTADDMRRAKRIRNAALQHLFIRKSFRPFKCLQCGKAFREK 452
           H +H Q  H       +      +   + R  +   QH  I    +P KC +CGK F+ K
Sbjct: 281 HLIHHQRIHTG-----EKPYICSECGSSFRKHSNLTQHQRIHTGEKPHKCDECGKTFQTK 335

Query: 453 DKLDQHLRFHGREGNCPLTCDLCNKGFISSTSLESHMKLHSDQKTYSCIFCPESFDRLDL 512
             L QH R H   G  P  C  C K F  S SL  H ++H+ +K Y C  C ++F +   
Sbjct: 336 ANLSQHQRIHS--GEKPYKCKECGKAFCQSPSLIKHQRIHTGEKPYKCKECGKAFTQSTP 393

Query: 513 LKDHVAIHINDGYFTCPTCKKRFPDFIQVKKHVRSFHSEKIYQCTECDKAFCRPDKLRLH 572
           L  H  IH  +  + C  C K F   I + +H RS   EK Y+C EC K F +   L  H
Sbjct: 394 LTKHQRIHTGERPYKCSECGKAFIQSICLIRHQRSHTGEKPYKCNECGKGFNQNTCLTQH 453

Query: 573 MLRHSDRKDFLCSTCGKQFKRKDKLREHMQRMHNPEREAKKADRISRSKTF-KPRITSTD 631
           M  H+  K + C  CGK F     L EH  R H  E+  K ++     KTF K    S  
Sbjct: 454 MRIHTGEKPYKCKECGKAFAHSSSLTEH-HRTHTGEKLYKCSE---CEKTFRKYAHLSEH 509

Query: 632 YDSFT----FKCRLCMMGFRRRGMLVNH 655
           Y   T    ++C  C   FR   +L  H
Sbjct: 510 YRIHTGEKPYECIECGKFFRHSSVLFRH 537



 Score =  141 bits (355), Expect = 4e-33
 Identities = 91/294 (30%), Positives = 126/294 (42%), Gaps = 29/294 (9%)

Query: 422 RIRNAALQHLFIRKSFRPFKCLQCGKAFREKDKLDQHLRFHGREGNCPLTCDLCNKGFIS 481
           R R+   QH  I    +P+KC +CG +FR    L +H R H   G  P  C+ C K F  
Sbjct: 221 RCRSFLTQHQRIHTGEKPYKCNECGNSFRNHSHLTEHQRIH--TGEKPYKCNRCGKAFNQ 278

Query: 482 STSLESHMKLHSDQKTYSCIFCPESFDRLDLLKDHVAIHINDGYFTCPTCKKRFPDFIQV 541
           +T L  H ++H+ +K Y C  C  SF +   L  H  IH  +    C  C K F     +
Sbjct: 279 NTHLIHHQRIHTGEKPYICSECGSSFRKHSNLTQHQRIHTGEKPHKCDECGKTFQTKANL 338

Query: 542 KKHVRSFHSEKIYQCTECDKAFCRPDKLRLHMLRHSDRKDFLCSTCGKQFKRKDKLREHM 601
            +H R    EK Y+C EC KAFC+   L  H   H+  K + C  CGK F +   L +H 
Sbjct: 339 SQHQRIHSGEKPYKCKECGKAFCQSPSLIKHQRIHTGEKPYKCKECGKAFTQSTPLTKH- 397

Query: 602 QRMHNPEREAKKADRISRSKTFKPRITSTDYD-SFT----FKCRLCMMGFRRRGMLVNHL 656
           QR+H  ER  K ++     K F   I    +  S T    +KC  C  GF +   L  H+
Sbjct: 398 QRIHTGERPYKCSE---CGKAFIQSICLIRHQRSHTGEKPYKCNECGKGFNQNTCLTQHM 454

Query: 657 SKRHPDMKIEEVPELTLPIIKPNRDYFCQYCDKVYKSASKRKAHILKNHPGAEL 710
                             I    + Y C+ C K +  +S    H  + H G +L
Sbjct: 455 R-----------------IHTGEKPYKCKECGKAFAHSSSLTEH-HRTHTGEKL 490



 Score =  133 bits (335), Expect = 7e-31
 Identities = 98/346 (28%), Positives = 149/346 (43%), Gaps = 34/346 (9%)

Query: 438 RPFKCLQCGKAFREKDKLDQHLRFHGREGNCPLTCDLCNKGFISSTSLESHMKLHSDQKT 497
           + +KC +CGK F +   L QH R H   G  P TC+ C K F  S+ L  H ++H+  K 
Sbjct: 153 KSWKCNECGKTFTQSSSLTQHQRTH--TGERPYTCEECGKAFSRSSFLVQHQRIHTGVKP 210

Query: 498 YSCIFCPESFDRLDLLKDHVAIHINDGYFTCPTCKKRFPDFIQVKKHVRSFHSEKIYQCT 557
           Y C  C ++F     L  H  IH  +  + C  C   F +   + +H R    EK Y+C 
Sbjct: 211 YGCEQCGKTFRCRSFLTQHQRIHTGEKPYKCNECGNSFRNHSHLTEHQRIHTGEKPYKCN 270

Query: 558 ECDKAFCRPDKLRLHMLRHSDRKDFLCSTCGKQFKRKDKLREHMQRMHNPEREAKKADRI 617
            C KAF +   L  H   H+  K ++CS CG  F++   L +H QR+H  E+   K D  
Sbjct: 271 RCGKAFNQNTHLIHHQRIHTGEKPYICSECGSSFRKHSNLTQH-QRIHTGEK-PHKCDEC 328

Query: 618 SRSKTFKPRITSTDYDSF-----TFKCRLCMMGFRRRGMLVNHLSKRHPDMKIEEVPEL- 671
              KTF+ +   + +         +KC+ C   F +   L+ H  + H   K  +  E  
Sbjct: 329 --GKTFQTKANLSQHQRIHSGEKPYKCKECGKAFCQSPSLIKH-QRIHTGEKPYKCKECG 385

Query: 672 -----TLPIIK------PNRDYFCQYCDKVYKSASKRKAHILKNHPGAELPPSIRKLRPA 720
                + P+ K        R Y C  C K +  +     H  ++H G E P    K    
Sbjct: 386 KAFTQSTPLTKHQRIHTGERPYKCSECGKAFIQSICLIRH-QRSHTG-EKP---YKCNEC 440

Query: 721 GPG-EPDPMLSTHTQL-TGTIATPPVCCPHCSKQYSSKTKMVQHIR 764
           G G   +  L+ H ++ TG     P  C  C K ++  + + +H R
Sbjct: 441 GKGFNQNTCLTQHMRIHTG---EKPYKCKECGKAFAHSSSLTEHHR 483



 Score =  123 bits (309), Expect = 8e-28
 Identities = 61/179 (34%), Positives = 91/179 (50%), Gaps = 3/179 (1%)

Query: 428 LQHLFIRKSFRPFKCLQCGKAFREKDKLDQHLRFHGREGNCPLTCDLCNKGFISSTSLES 487
           ++H  I    +P+KC +CGKAF +   L +H R H   G  P  C  C K FI S  L  
Sbjct: 367 IKHQRIHTGEKPYKCKECGKAFTQSTPLTKHQRIH--TGERPYKCSECGKAFIQSICLIR 424

Query: 488 HMKLHSDQKTYSCIFCPESFDRLDLLKDHVAIHINDGYFTCPTCKKRFPDFIQVKKHVRS 547
           H + H+ +K Y C  C + F++   L  H+ IH  +  + C  C K F     + +H R+
Sbjct: 425 HQRSHTGEKPYKCNECGKGFNQNTCLTQHMRIHTGEKPYKCKECGKAFAHSSSLTEHHRT 484

Query: 548 FHSEKIYQCTECDKAFCRPDKLRLHMLRHSDRKDFLCSTCGKQFKRKDKLREHMQRMHN 606
              EK+Y+C+EC+K F +   L  H   H+  K + C  CGK F+    L  H Q++H+
Sbjct: 485 HTGEKLYKCSECEKTFRKYAHLSEHYRIHTGEKPYECIECGKFFRHSSVLFRH-QKLHS 542



 Score = 76.6 bits (187), Expect = 1e-13
 Identities = 67/277 (24%), Positives = 105/277 (37%), Gaps = 28/277 (10%)

Query: 491 LHSDQKTYSCIFCPESFDRLDLLKDHVAIHINDGYFTCPTCKKRFPDFIQVKKHVRSFHS 550
           L + +K++ C  C ++F +   L  H   H  +  +TC  C K F     + +H R    
Sbjct: 148 LCTQKKSWKCNECGKTFTQSSSLTQHQRTHTGERPYTCEECGKAFSRSSFLVQHQRIHTG 207

Query: 551 EKIYQCTECDKAFCRPDKLRLHMLRHSDRKDFLCSTCGKQFKRKDKLREHMQRMHNPERE 610
            K Y C +C K F     L  H   H+  K + C+ CG  F+    L EH QR+H  E+ 
Sbjct: 208 VKPYGCEQCGKTFRCRSFLTQHQRIHTGEKPYKCNECGNSFRNHSHLTEH-QRIHTGEKP 266

Query: 611 AK--KADRISRSKTFKPRITSTDYDSFTFKCRLCMMGFRRRGMLVNHLSKRHPDMKIEEV 668
            K  +  +     T              + C  C   FR+   L  H      +      
Sbjct: 267 YKCNRCGKAFNQNTHLIHHQRIHTGEKPYICSECGSSFRKHSNLTQHQRIHTGE------ 320

Query: 669 PELTLPIIKPNRDYFCQYCDKVYKSASKRKAHILKNHPGAELPPSIRKLRPAGPGEPDPM 728
                   KP++   C  C K +++ +    H  + H G E P   ++   A      P 
Sbjct: 321 --------KPHK---CDECGKTFQTKANLSQH-QRIHSG-EKPYKCKECGKAFC--QSPS 365

Query: 729 LSTHTQL-TGTIATPPVCCPHCSKQYSSKTKMVQHIR 764
           L  H ++ TG     P  C  C K ++  T + +H R
Sbjct: 366 LIKHQRIHTG---EKPYKCKECGKAFTQSTPLTKHQR 399



 Score = 67.4 bits (163), Expect = 7e-11
 Identities = 33/95 (34%), Positives = 45/95 (47%), Gaps = 2/95 (2%)

Query: 429 QHLFIRKSFRPFKCLQCGKAFREKDKLDQHLRFHGREGNCPLTCDLCNKGFISSTSLESH 488
           QH+ I    +P+KC +CGKAF     L +H R H   G     C  C K F     L  H
Sbjct: 452 QHMRIHTGEKPYKCKECGKAFAHSSSLTEHHRTH--TGEKLYKCSECEKTFRKYAHLSEH 509

Query: 489 MKLHSDQKTYSCIFCPESFDRLDLLKDHVAIHIND 523
            ++H+ +K Y CI C + F    +L  H  +H  D
Sbjct: 510 YRIHTGEKPYECIECGKFFRHSSVLFRHQKLHSGD 544


>gi|21361857 zinc finger protein 502 [Homo sapiens]
          Length = 544

 Score =  147 bits (371), Expect = 5e-35
 Identities = 126/448 (28%), Positives = 176/448 (39%), Gaps = 51/448 (11%)

Query: 229 VEPKQELKVWYAASYAEFVNQKIHDISEEER-KVLREQEKNWPCYECNRRFISSEQLQQH 287
           V  ++ L  W      E  N + +DIS++ +   L  Q+K+W C EC + F  S  L QH
Sbjct: 120 VSTEESLHQW------ETSNIQTNDISDQSKCPTLCTQKKSWKCNECGKTFTQSSSLTQH 173

Query: 288 LNSHDEKLDVFSRTRGRGRGRGK-----RRFGPGRRPG---------RPPKFIRLEITSE 333
             +H  +        G+   R       +R   G +P          R   F+       
Sbjct: 174 QRTHTGERPYTCEECGKAFSRSSFLVQHQRIHTGVKPYGCEQCGKTFRCRSFLTQHQRIH 233

Query: 334 NGEKSDDGTQDLLHFPTKEQFDEAEPATLNGLDQPEQTTIPIPQLPQE-TQSSLEHEPET 392
            GEK           P K   +E   +  N     E   I   + P +  +        T
Sbjct: 234 TGEK-----------PYK--CNECGNSFRNHSHLTEHQRIHTGEKPYKCNRCGKAFNQNT 280

Query: 393 HTLHLQPQHEESVVPTQSTLTADDMRRAKRIRNAALQHLFIRKSFRPFKCLQCGKAFREK 452
           H +H Q  H       +      +   + R  +   QH  I    +P KC +CGK F+ K
Sbjct: 281 HLIHHQRIHTG-----EKPYICSECGSSFRKHSNLTQHQRIHTGEKPHKCDECGKTFQTK 335

Query: 453 DKLDQHLRFHGREGNCPLTCDLCNKGFISSTSLESHMKLHSDQKTYSCIFCPESFDRLDL 512
             L QH R H   G  P  C  C K F  S SL  H ++H+ +K Y C  C ++F +   
Sbjct: 336 ANLSQHQRIHS--GEKPYKCKECGKAFCQSPSLIKHQRIHTGEKPYKCKECGKAFTQSTP 393

Query: 513 LKDHVAIHINDGYFTCPTCKKRFPDFIQVKKHVRSFHSEKIYQCTECDKAFCRPDKLRLH 572
           L  H  IH  +  + C  C K F   I + +H RS   EK Y+C EC K F +   L  H
Sbjct: 394 LTKHQRIHTGERPYKCSECGKAFIQSICLIRHQRSHTGEKPYKCNECGKGFNQNTCLTQH 453

Query: 573 MLRHSDRKDFLCSTCGKQFKRKDKLREHMQRMHNPEREAKKADRISRSKTF-KPRITSTD 631
           M  H+  K + C  CGK F     L EH  R H  E+  K ++     KTF K    S  
Sbjct: 454 MRIHTGEKPYKCKECGKAFAHSSSLTEH-HRTHTGEKLYKCSE---CEKTFRKYAHLSEH 509

Query: 632 YDSFT----FKCRLCMMGFRRRGMLVNH 655
           Y   T    ++C  C   FR   +L  H
Sbjct: 510 YRIHTGEKPYECIECGKFFRHSSVLFRH 537



 Score =  141 bits (355), Expect = 4e-33
 Identities = 91/294 (30%), Positives = 126/294 (42%), Gaps = 29/294 (9%)

Query: 422 RIRNAALQHLFIRKSFRPFKCLQCGKAFREKDKLDQHLRFHGREGNCPLTCDLCNKGFIS 481
           R R+   QH  I    +P+KC +CG +FR    L +H R H   G  P  C+ C K F  
Sbjct: 221 RCRSFLTQHQRIHTGEKPYKCNECGNSFRNHSHLTEHQRIH--TGEKPYKCNRCGKAFNQ 278

Query: 482 STSLESHMKLHSDQKTYSCIFCPESFDRLDLLKDHVAIHINDGYFTCPTCKKRFPDFIQV 541
           +T L  H ++H+ +K Y C  C  SF +   L  H  IH  +    C  C K F     +
Sbjct: 279 NTHLIHHQRIHTGEKPYICSECGSSFRKHSNLTQHQRIHTGEKPHKCDECGKTFQTKANL 338

Query: 542 KKHVRSFHSEKIYQCTECDKAFCRPDKLRLHMLRHSDRKDFLCSTCGKQFKRKDKLREHM 601
            +H R    EK Y+C EC KAFC+   L  H   H+  K + C  CGK F +   L +H 
Sbjct: 339 SQHQRIHSGEKPYKCKECGKAFCQSPSLIKHQRIHTGEKPYKCKECGKAFTQSTPLTKH- 397

Query: 602 QRMHNPEREAKKADRISRSKTFKPRITSTDYD-SFT----FKCRLCMMGFRRRGMLVNHL 656
           QR+H  ER  K ++     K F   I    +  S T    +KC  C  GF +   L  H+
Sbjct: 398 QRIHTGERPYKCSE---CGKAFIQSICLIRHQRSHTGEKPYKCNECGKGFNQNTCLTQHM 454

Query: 657 SKRHPDMKIEEVPELTLPIIKPNRDYFCQYCDKVYKSASKRKAHILKNHPGAEL 710
                             I    + Y C+ C K +  +S    H  + H G +L
Sbjct: 455 R-----------------IHTGEKPYKCKECGKAFAHSSSLTEH-HRTHTGEKL 490



 Score =  133 bits (335), Expect = 7e-31
 Identities = 98/346 (28%), Positives = 149/346 (43%), Gaps = 34/346 (9%)

Query: 438 RPFKCLQCGKAFREKDKLDQHLRFHGREGNCPLTCDLCNKGFISSTSLESHMKLHSDQKT 497
           + +KC +CGK F +   L QH R H   G  P TC+ C K F  S+ L  H ++H+  K 
Sbjct: 153 KSWKCNECGKTFTQSSSLTQHQRTH--TGERPYTCEECGKAFSRSSFLVQHQRIHTGVKP 210

Query: 498 YSCIFCPESFDRLDLLKDHVAIHINDGYFTCPTCKKRFPDFIQVKKHVRSFHSEKIYQCT 557
           Y C  C ++F     L  H  IH  +  + C  C   F +   + +H R    EK Y+C 
Sbjct: 211 YGCEQCGKTFRCRSFLTQHQRIHTGEKPYKCNECGNSFRNHSHLTEHQRIHTGEKPYKCN 270

Query: 558 ECDKAFCRPDKLRLHMLRHSDRKDFLCSTCGKQFKRKDKLREHMQRMHNPEREAKKADRI 617
            C KAF +   L  H   H+  K ++CS CG  F++   L +H QR+H  E+   K D  
Sbjct: 271 RCGKAFNQNTHLIHHQRIHTGEKPYICSECGSSFRKHSNLTQH-QRIHTGEK-PHKCDEC 328

Query: 618 SRSKTFKPRITSTDYDSF-----TFKCRLCMMGFRRRGMLVNHLSKRHPDMKIEEVPEL- 671
              KTF+ +   + +         +KC+ C   F +   L+ H  + H   K  +  E  
Sbjct: 329 --GKTFQTKANLSQHQRIHSGEKPYKCKECGKAFCQSPSLIKH-QRIHTGEKPYKCKECG 385

Query: 672 -----TLPIIK------PNRDYFCQYCDKVYKSASKRKAHILKNHPGAELPPSIRKLRPA 720
                + P+ K        R Y C  C K +  +     H  ++H G E P    K    
Sbjct: 386 KAFTQSTPLTKHQRIHTGERPYKCSECGKAFIQSICLIRH-QRSHTG-EKP---YKCNEC 440

Query: 721 GPG-EPDPMLSTHTQL-TGTIATPPVCCPHCSKQYSSKTKMVQHIR 764
           G G   +  L+ H ++ TG     P  C  C K ++  + + +H R
Sbjct: 441 GKGFNQNTCLTQHMRIHTG---EKPYKCKECGKAFAHSSSLTEHHR 483



 Score =  123 bits (309), Expect = 8e-28
 Identities = 61/179 (34%), Positives = 91/179 (50%), Gaps = 3/179 (1%)

Query: 428 LQHLFIRKSFRPFKCLQCGKAFREKDKLDQHLRFHGREGNCPLTCDLCNKGFISSTSLES 487
           ++H  I    +P+KC +CGKAF +   L +H R H   G  P  C  C K FI S  L  
Sbjct: 367 IKHQRIHTGEKPYKCKECGKAFTQSTPLTKHQRIH--TGERPYKCSECGKAFIQSICLIR 424

Query: 488 HMKLHSDQKTYSCIFCPESFDRLDLLKDHVAIHINDGYFTCPTCKKRFPDFIQVKKHVRS 547
           H + H+ +K Y C  C + F++   L  H+ IH  +  + C  C K F     + +H R+
Sbjct: 425 HQRSHTGEKPYKCNECGKGFNQNTCLTQHMRIHTGEKPYKCKECGKAFAHSSSLTEHHRT 484

Query: 548 FHSEKIYQCTECDKAFCRPDKLRLHMLRHSDRKDFLCSTCGKQFKRKDKLREHMQRMHN 606
              EK+Y+C+EC+K F +   L  H   H+  K + C  CGK F+    L  H Q++H+
Sbjct: 485 HTGEKLYKCSECEKTFRKYAHLSEHYRIHTGEKPYECIECGKFFRHSSVLFRH-QKLHS 542



 Score = 76.6 bits (187), Expect = 1e-13
 Identities = 67/277 (24%), Positives = 105/277 (37%), Gaps = 28/277 (10%)

Query: 491 LHSDQKTYSCIFCPESFDRLDLLKDHVAIHINDGYFTCPTCKKRFPDFIQVKKHVRSFHS 550
           L + +K++ C  C ++F +   L  H   H  +  +TC  C K F     + +H R    
Sbjct: 148 LCTQKKSWKCNECGKTFTQSSSLTQHQRTHTGERPYTCEECGKAFSRSSFLVQHQRIHTG 207

Query: 551 EKIYQCTECDKAFCRPDKLRLHMLRHSDRKDFLCSTCGKQFKRKDKLREHMQRMHNPERE 610
            K Y C +C K F     L  H   H+  K + C+ CG  F+    L EH QR+H  E+ 
Sbjct: 208 VKPYGCEQCGKTFRCRSFLTQHQRIHTGEKPYKCNECGNSFRNHSHLTEH-QRIHTGEKP 266

Query: 611 AK--KADRISRSKTFKPRITSTDYDSFTFKCRLCMMGFRRRGMLVNHLSKRHPDMKIEEV 668
            K  +  +     T              + C  C   FR+   L  H      +      
Sbjct: 267 YKCNRCGKAFNQNTHLIHHQRIHTGEKPYICSECGSSFRKHSNLTQHQRIHTGE------ 320

Query: 669 PELTLPIIKPNRDYFCQYCDKVYKSASKRKAHILKNHPGAELPPSIRKLRPAGPGEPDPM 728
                   KP++   C  C K +++ +    H  + H G E P   ++   A      P 
Sbjct: 321 --------KPHK---CDECGKTFQTKANLSQH-QRIHSG-EKPYKCKECGKAFC--QSPS 365

Query: 729 LSTHTQL-TGTIATPPVCCPHCSKQYSSKTKMVQHIR 764
           L  H ++ TG     P  C  C K ++  T + +H R
Sbjct: 366 LIKHQRIHTG---EKPYKCKECGKAFTQSTPLTKHQR 399



 Score = 67.4 bits (163), Expect = 7e-11
 Identities = 33/95 (34%), Positives = 45/95 (47%), Gaps = 2/95 (2%)

Query: 429 QHLFIRKSFRPFKCLQCGKAFREKDKLDQHLRFHGREGNCPLTCDLCNKGFISSTSLESH 488
           QH+ I    +P+KC +CGKAF     L +H R H   G     C  C K F     L  H
Sbjct: 452 QHMRIHTGEKPYKCKECGKAFAHSSSLTEHHRTH--TGEKLYKCSECEKTFRKYAHLSEH 509

Query: 489 MKLHSDQKTYSCIFCPESFDRLDLLKDHVAIHIND 523
            ++H+ +K Y CI C + F    +L  H  +H  D
Sbjct: 510 YRIHTGEKPYECIECGKFFRHSSVLFRHQKLHSGD 544


>gi|172072608 zinc finger protein 624 [Homo sapiens]
          Length = 865

 Score =  147 bits (370), Expect = 7e-35
 Identities = 127/518 (24%), Positives = 198/518 (38%), Gaps = 109/518 (21%)

Query: 258 ERKVLREQEKNWPCYECNRRFISSEQLQQHLNSHDEKLDVFSRTRGRGRGRGKR-----R 312
           + K +   EK + C EC + FI+S  L  H   H ++        G+   +  R     R
Sbjct: 321 QHKKIHTGEKPYKCNECGKAFIASSSLMVHQRIHTKEKPYQCNVCGKSFSQCARLNQHQR 380

Query: 313 FGPGRRPGRPPKFIRLEITSENGEKSDDGTQDLLHFPTKEQFDEAEPATLNGLDQPEQTT 372
              G +P +          SE G+   D                                
Sbjct: 381 IQTGEKPYK---------CSECGKAFSD-------------------------------- 399

Query: 373 IPIPQLPQETQSSLEHEPETHTLHLQPQHEESVVPTQSTLTADDMRRAKRIRNAALQHLF 432
                     +S L    ETH               +     DD  +A R ++    H  
Sbjct: 400 ----------KSKLARHQETHN-------------GEKPYKCDDCGKAFRNKSYLSVHQK 436

Query: 433 IRKSFRPFKCLQCGKAFREKDKLDQHLRFHGREGNCPLTCDLCNKGFISSTSLESHMKLH 492
                +P++C +CGK+F+     + H R H   G  P  C+ C K + S++SL  H++ H
Sbjct: 437 THTEEKPYQCNECGKSFKNTTIFNVHQRIH--TGEKPFRCNECGKAYRSNSSLIVHIRTH 494

Query: 493 SDQKTYSCIFCPESFDRLDLLKDHVAIHINDGYFTCPTCKKRFPDFIQVKKHVRSFHSEK 552
           + +K Y C  C ++F+R+    +H  IH  +  + C  C K F ++  +  H R    EK
Sbjct: 495 TGEKPYECNECGKAFNRIANFTEHQRIHTGEKPYKCNECGKAFINYSCLTVHHRMHTGEK 554

Query: 553 IYQCTECDKAFCRPDKLRLHMLRHSDRKDFLCSTCGKQFKRKDKLREHMQRMHNPEREAK 612
            Y+CTEC KAF R   L +H   H++ K +LC+ CG+ F+ K  L  H QR+H  E+  K
Sbjct: 555 PYKCTECGKAFMRSSSLIIHQRIHTEEKPYLCNECGESFRIKSHLTVH-QRIHTGEKPYK 613

Query: 613 KADRISRSKTFKPRITSTDYDSF-----TFKCRLCMMGFRRRGMLVNHLSKRHPDMKIEE 667
             D     + F   +   ++         +KC  C   FR +  L+ H  + H   K   
Sbjct: 614 CTD---CERAFTKMVNLKEHQKIHTGVKPYKCYDCGKSFRTKSYLIVH-QRTHTGEK--- 666

Query: 668 VPELTLPIIKPNRDYFCQYCDKVYKSASKRKAHILKNHPGAELPPSIR---KLRPAGPGE 724
                         Y C  C+K + + S+   H  + H G E P       K+  +  G 
Sbjct: 667 -------------PYKCNECEKAFTNTSQLTVH-QRRHTG-EKPYKCNECGKVFTSNSG- 710

Query: 725 PDPMLSTHTQLTGTIATPPVCCPHCSKQYSSKTKMVQH 762
                +TH Q T T    P  C  C K +S    + +H
Sbjct: 711 ----FNTH-QRTHT-GEKPFKCNDCGKAFSQMVHVTEH 742



 Score =  136 bits (342), Expect = 1e-31
 Identities = 76/242 (31%), Positives = 113/242 (46%), Gaps = 11/242 (4%)

Query: 419 RAKRIRNAALQHLFIRKSFRPFKCLQCGKAFREKDKLDQHLRFHGREGNCPLTCDLCNKG 478
           +A   R+  +QH       +P++C +CGK F +   L QH + H   G  P  C+ C K 
Sbjct: 283 KAFHYRSLLIQHQRTHTKEKPYECNECGKTFSQPSYLSQHKKIH--TGEKPYKCNECGKA 340

Query: 479 FISSTSLESHMKLHSDQKTYSCIFCPESFDRLDLLKDHVAIHINDGYFTCPTCKKRFPDF 538
           FI+S+SL  H ++H+ +K Y C  C +SF +   L  H  I   +  + C  C K F D 
Sbjct: 341 FIASSSLMVHQRIHTKEKPYQCNVCGKSFSQCARLNQHQRIQTGEKPYKCSECGKAFSDK 400

Query: 539 IQVKKHVRSFHSEKIYQCTECDKAFCRPDKLRLHMLRHSDRKDFLCSTCGKQFKRKDKLR 598
            ++ +H  + + EK Y+C +C KAF     L +H   H++ K + C+ CGK FK      
Sbjct: 401 SKLARHQETHNGEKPYKCDDCGKAFRNKSYLSVHQKTHTEEKPYQCNECGKSFKNTTIFN 460

Query: 599 EHMQRMHNPER-----EAKKADRISRSKTFKPRITSTDYDSFTFKCRLCMMGFRRRGMLV 653
            H QR+H  E+     E  KA R + S     R   T      ++C  C   F R     
Sbjct: 461 VH-QRIHTGEKPFRCNECGKAYRSNSSLIVHIR---THTGEKPYECNECGKAFNRIANFT 516

Query: 654 NH 655
            H
Sbjct: 517 EH 518



 Score =  134 bits (337), Expect = 4e-31
 Identities = 99/342 (28%), Positives = 138/342 (40%), Gaps = 34/342 (9%)

Query: 429 QHLFIRKSFRPFKCLQCGKAFREKDKLDQHLRFHGREGNCPLTCDLCNKGFISSTSLESH 488
           QH  I+   +P+KC +CGKAF +K KL +H   H   G  P  CD C K F + + L  H
Sbjct: 377 QHQRIQTGEKPYKCSECGKAFSDKSKLARHQETHN--GEKPYKCDDCGKAFRNKSYLSVH 434

Query: 489 MKLHSDQKTYSCIFCPESFDRLDLLKDHVAIHINDGYFTCPTCKKRFPDFIQVKKHVRSF 548
            K H+++K Y C  C +SF    +   H  IH  +  F C  C K +     +  H+R+ 
Sbjct: 435 QKTHTEEKPYQCNECGKSFKNTTIFNVHQRIHTGEKPFRCNECGKAYRSNSSLIVHIRTH 494

Query: 549 HSEKIYQCTECDKAFCRPDKLRLHMLRHSDRKDFLCSTCGKQFKRKDKLREHMQRMHNPE 608
             EK Y+C EC KAF R      H   H+  K + C+ CGK F     L  H  RMH  E
Sbjct: 495 TGEKPYECNECGKAFNRIANFTEHQRIHTGEKPYKCNECGKAFINYSCLTVH-HRMHTGE 553

Query: 609 R-----EAKKADRISRSKTFKPRITSTDYDSFTFKCRLCMMGFRRRGMLVNHLSKRHPDM 663
           +     E  KA   S S     RI +   +   + C  C   FR +  L  H        
Sbjct: 554 KPYKCTECGKAFMRSSSLIIHQRIHT---EEKPYLCNECGESFRIKSHLTVHQR------ 604

Query: 664 KIEEVPELTLPIIKPNRDYFCQYCDKVYKSASKRKAHILKNHPGAELPPSIRKLRPAGPG 723
                      I    + Y C  C++ +      K H  K H G +      K    G  
Sbjct: 605 -----------IHTGEKPYKCTDCERAFTKMVNLKEH-QKIHTGVK----PYKCYDCGKS 648

Query: 724 EPDPMLSTHTQLTGTIATPPVCCPHCSKQYSSKTKMVQHIRK 765
                     Q T T    P  C  C K +++ +++  H R+
Sbjct: 649 FRTKSYLIVHQRTHT-GEKPYKCNECEKAFTNTSQLTVHQRR 689



 Score =  129 bits (325), Expect = 1e-29
 Identities = 115/428 (26%), Positives = 167/428 (39%), Gaps = 50/428 (11%)

Query: 370 QTTIPIPQLPQET-----QSSLEHEP--ETHTLHLQPQHEESVVPTQSTLTAD------- 415
           Q  IP+ + P        +S L  EP   T  LH + Q +E        L  D       
Sbjct: 188 QRIIPLKKTPTSQRGFRFESILIPEPGIATEELHSRCQTQEENFTENLNLITDTHLGKII 247

Query: 416 --DMRRAKRIRNAALQHLFIRKSFR--PFKCLQCGKAFREKDKLDQHLRFHGREGNCPLT 471
             +M+ +K IR  +   L  + + +  P+KC  C KAF  +  L QH R H +E   P  
Sbjct: 248 CKEMKGSKAIRQTSELTLGKKSNNKEKPYKCSTCEKAFHYRSLLIQHQRTHTKEK--PYE 305

Query: 472 CDLCNKGFISSTSLESHMKLHSDQKTYSCIFCPESFDRLDLLKDHVAIHINDGYFTCPTC 531
           C+ C K F   + L  H K+H+ +K Y C  C ++F     L  H  IH  +  + C  C
Sbjct: 306 CNECGKTFSQPSYLSQHKKIHTGEKPYKCNECGKAFIASSSLMVHQRIHTKEKPYQCNVC 365

Query: 532 KKRFPDFIQVKKHVRSFHSEKIYQCTECDKAFCRPDKLRLHMLRHSDRKDFLCSTCGKQF 591
            K F    ++ +H R    EK Y+C+EC KAF    KL  H   H+  K + C  CGK F
Sbjct: 366 GKSFSQCARLNQHQRIQTGEKPYKCSECGKAFSDKSKLARHQETHNGEKPYKCDDCGKAF 425

Query: 592 KRKDKLREHMQRMHNPER--EAKKADRISRSKTFKPRITSTDYDSFTFKCRLCMMGFRRR 649
           + K  L  H Q+ H  E+  +  +  +  ++ T              F+C  C   +R  
Sbjct: 426 RNKSYLSVH-QKTHTEEKPYQCNECGKSFKNTTIFNVHQRIHTGEKPFRCNECGKAYRSN 484

Query: 650 GMLVNHLSKRHPDMKIEEVPELTLPIIKPNRDYFCQYCDKVYKSASKRKAHILKNHPGAE 709
             L+ H+ + H   K                 Y C  C K +   +    H  + H G E
Sbjct: 485 SSLIVHI-RTHTGEK----------------PYECNECGKAFNRIANFTEH-QRIHTG-E 525

Query: 710 LPPSIRKLRPAGPGEPDPMLST--HTQLTGTIATPPVCCPHCSKQYSSKTKMVQHIRKKH 767
            P    K    G    +    T  H   TG     P  C  C K +   + ++ H R   
Sbjct: 526 KP---YKCNECGKAFINYSCLTVHHRMHTG---EKPYKCTECGKAFMRSSSLIIHQRIHT 579

Query: 768 PEFAQLSN 775
            E   L N
Sbjct: 580 EEKPYLCN 587



 Score =  124 bits (312), Expect = 3e-28
 Identities = 84/290 (28%), Positives = 119/290 (41%), Gaps = 43/290 (14%)

Query: 430 HLFIRKSFRPFKCLQCGKAFREKDKLDQHLRFHGREGNCPLTCDLCNKGFISSTSLESHM 489
           H  I    +P+ C +CG++FR K  L  H R H   G  P  C  C + F    +L+ H 
Sbjct: 574 HQRIHTEEKPYLCNECGESFRIKSHLTVHQRIH--TGEKPYKCTDCERAFTKMVNLKEHQ 631

Query: 490 KLHSDQKTYSCIFCPESFDRLDLLKDHVAIHINDGYFTCPTCKKRFPDFIQVKKHVRSFH 549
           K+H+  K Y C  C +SF     L  H   H  +  + C  C+K F +  Q+  H R   
Sbjct: 632 KIHTGVKPYKCYDCGKSFRTKSYLIVHQRTHTGEKPYKCNECEKAFTNTSQLTVHQRRHT 691

Query: 550 SEKIYQCTECDKAFCRPDKLRLHMLRHSDRKDFLCSTCGKQFKRKDKLREHMQRMHNPER 609
            EK Y+C EC K F        H   H+  K F C+ CGK F +   + EH Q++H+ E+
Sbjct: 692 GEKPYKCNECGKVFTSNSGFNTHQRTHTGEKPFKCNDCGKAFSQMVHVTEH-QKIHSGEK 750

Query: 610 EAKKADRISRSKTFKPRITSTDYDSFTFKCRLCMMGFRRRGMLVNHLSKRHPDMK----- 664
                                      +KC +C   FRR   L  H  + H   K     
Sbjct: 751 --------------------------PYKCDVCGKAFRRGSYLTVHW-RTHTGEKPYTCK 783

Query: 665 -----IEEVPELTL--PIIKPNRDYFCQYCDKVYKSASKRKAHILKNHPG 707
                   + +LTL   I    R Y C+ C K +++ S    H L+ H G
Sbjct: 784 ECGKGCITLSQLTLHQRIHTGERPYKCEECGKAFRTNSDFTVH-LRMHTG 832



 Score =  115 bits (288), Expect = 2e-25
 Identities = 58/173 (33%), Positives = 81/173 (46%), Gaps = 3/173 (1%)

Query: 438 RPFKCLQCGKAFREKDKLDQHLRFHGREGNCPLTCDLCNKGFISSTSLESHMKLHSDQKT 497
           +P+KC +CGK F      + H R H   G  P  C+ C K F     +  H K+HS +K 
Sbjct: 694 KPYKCNECGKVFTSNSGFNTHQRTH--TGEKPFKCNDCGKAFSQMVHVTEHQKIHSGEKP 751

Query: 498 YSCIFCPESFDRLDLLKDHVAIHINDGYFTCPTCKKRFPDFIQVKKHVRSFHSEKIYQCT 557
           Y C  C ++F R   L  H   H  +  +TC  C K      Q+  H R    E+ Y+C 
Sbjct: 752 YKCDVCGKAFRRGSYLTVHWRTHTGEKPYTCKECGKGCITLSQLTLHQRIHTGERPYKCE 811

Query: 558 ECDKAFCRPDKLRLHMLRHSDRKDFLCSTCGKQFKRKDKLREHMQRMHNPERE 610
           EC KAF       +H+  H+  K + C+ CGK F+    L  H QR+H  E +
Sbjct: 812 ECGKAFRTNSDFTVHLRMHTGEKPYKCNECGKAFRSSSSLTVH-QRIHQRETQ 863



 Score = 73.6 bits (179), Expect = 9e-13
 Identities = 39/123 (31%), Positives = 56/123 (45%), Gaps = 2/123 (1%)

Query: 429 QHLFIRKSFRPFKCLQCGKAFREKDKLDQHLRFHGREGNCPLTCDLCNKGFISSTSLESH 488
           +H  I    +P+KC  CGKAFR    L  H R H   G  P TC  C KG I+ + L  H
Sbjct: 741 EHQKIHSGEKPYKCDVCGKAFRRGSYLTVHWRTH--TGEKPYTCKECGKGCITLSQLTLH 798

Query: 489 MKLHSDQKTYSCIFCPESFDRLDLLKDHVAIHINDGYFTCPTCKKRFPDFIQVKKHVRSF 548
            ++H+ ++ Y C  C ++F        H+ +H  +  + C  C K F     +  H R  
Sbjct: 799 QRIHTGERPYKCEECGKAFRTNSDFTVHLRMHTGEKPYKCNECGKAFRSSSSLTVHQRIH 858

Query: 549 HSE 551
             E
Sbjct: 859 QRE 861



 Score = 41.6 bits (96), Expect = 0.004
 Identities = 19/51 (37%), Positives = 27/51 (52%)

Query: 415 DDMRRAKRIRNAALQHLFIRKSFRPFKCLQCGKAFREKDKLDQHLRFHGRE 465
           ++  +A R  +    HL +    +P+KC +CGKAFR    L  H R H RE
Sbjct: 811 EECGKAFRTNSDFTVHLRMHTGEKPYKCNECGKAFRSSSSLTVHQRIHQRE 861


>gi|48717241 zinc finger protein 425 [Homo sapiens]
          Length = 752

 Score =  147 bits (370), Expect = 7e-35
 Identities = 98/356 (27%), Positives = 155/356 (43%), Gaps = 36/356 (10%)

Query: 429 QHLFIRKSFRPFKCLQCGKAFREKDKLDQHLRFHGREGNCPLTCDLCNKGFISSTSLESH 488
           +HL +    +PF+C QC + FR K  +  HL  H   G  P  C  C + F    +L++H
Sbjct: 319 EHLRLHSGEKPFQCPQCDRCFRLKRGMKVHLTQHS--GKRPFHCPECGRSFSRKAALKTH 376

Query: 489 MKLHSDQKTYSCIFCPESFDRLDLLKDHVAIHINDGYFTCPTCKKRFPDFIQVKKHVRSF 548
            + HS++K +SC  C   F     L +H+ +H  +  F+CP C K F     +K H    
Sbjct: 377 QRTHSEEKPFSCGECGRKFIYKIKLDEHIRVHTGEKPFSCPECNKSFRLKRSLKAHGLQH 436

Query: 549 HSEKIYQCTECDKAFCRPDKLRLHMLRHSDRKDFLCSTCGKQFKRKDKLREHMQRMHNPE 608
             ++ +QC EC + F   + +R H   HS++K F C+ CGK+F R  KL  H  R+H+ +
Sbjct: 437 IGKRPFQCPECSRGFFWRNAMRAHQRLHSEQKPFPCAECGKRFTRPSKLACH-TRVHDRQ 495

Query: 609 REAKKADRISRSKTFKPRITSTDY-----DSFTFKCRLCMMGFRRRGMLVNHLSKRHPDM 663
           +E    +     KTF  +   T +         F C  C   FRRR  L  H ++ H   
Sbjct: 496 KEFPCGE---CKKTFSQQSRLTQHLKVHTTEKPFSCAECGRSFRRRAHLTEH-TRLHSGE 551

Query: 664 KIEEVPELTLP------------IIKPNRDYFCQYCDKVYKSASKRKAHILKNHPGA--- 708
           +  + PE                + +  + + C  CDK Y   S+   H L+ H G    
Sbjct: 552 EPFQCPECDKSFSWKASMKFHQRMHRDEKPFACGECDKTYTHQSQLTEH-LRLHSGEKPY 610

Query: 709 ELPPSIRKLRPAGPGEPDPMLSTHTQLTGTIATPPVCCPHCSKQYSSKTKMVQHIR 764
           + P   +  R  G        +  + L       P  C  C K ++ + ++ +HIR
Sbjct: 611 QCPECEKTFRLKG--------NLKSHLLQHSGQKPFSCVMCGKSFTQQYRLTEHIR 658



 Score =  142 bits (357), Expect = 2e-33
 Identities = 102/372 (27%), Positives = 157/372 (42%), Gaps = 38/372 (10%)

Query: 419 RAKRIRNAALQHLFIRKSFRPFKCLQCGKAFREKDKLDQHLRFHGREGNCPLTCDLCNKG 478
           R  R++     HL      RPF C +CG++F  K  L  H R H  E   P +C  C + 
Sbjct: 337 RCFRLKRGMKVHLTQHSGKRPFHCPECGRSFSRKAALKTHQRTHSEEK--PFSCGECGRK 394

Query: 479 FISSTSLESHMKLHSDQKTYSCIFCPESFDRLDLLKDHVAIHINDGYFTCPTCKKRFPDF 538
           FI    L+ H+++H+ +K +SC  C +SF     LK H   HI    F CP C + F   
Sbjct: 395 FIYKIKLDEHIRVHTGEKPFSCPECNKSFRLKRSLKAHGLQHIGKRPFQCPECSRGFFWR 454

Query: 539 IQVKKHVRSFHSEKIYQCTECDKAFCRPDKLRLHMLRHSDRKDFLCSTCGKQFKRKDKLR 598
             ++ H R    +K + C EC K F RP KL  H   H  +K+F C  C K F ++ +L 
Sbjct: 455 NAMRAHQRLHSEQKPFPCAECGKRFTRPSKLACHTRVHDRQKEFPCGECKKTFSQQSRLT 514

Query: 599 EHMQRMHNPEREAKKADRISRSKTFKPRITSTDYDSF-----TFKCRLCMMGFRRRGMLV 653
           +H+ ++H  E+    A+     ++F+ R   T++         F+C  C   F  +  + 
Sbjct: 515 QHL-KVHTTEKPFSCAEC---GRSFRRRAHLTEHTRLHSGEEPFQCPECDKSFSWKASMK 570

Query: 654 NHLSKRHPDMK----------IEEVPELT--LPIIKPNRDYFCQYCDKVYKSASKRKAHI 701
            H  + H D K               +LT  L +    + Y C  C+K ++     K+H+
Sbjct: 571 FH-QRMHRDEKPFACGECDKTYTHQSQLTEHLRLHSGEKPYQCPECEKTFRLKGNLKSHL 629

Query: 702 LKNHPGAELPPSIRKLRPAGPGEPDPMLSTHTQLTGTIAT----PPVCCPHCSKQYSSKT 757
           L+ H G          +P          +   +LT  I       P  CP C K Y  + 
Sbjct: 630 LQ-HSGQ---------KPFSCVMCGKSFTQQYRLTEHIRVHSGEKPFQCPECDKSYCIRG 679

Query: 758 KMVQHIRKKHPE 769
            +  H+ K   E
Sbjct: 680 SLKVHLYKHSGE 691



 Score =  140 bits (354), Expect = 5e-33
 Identities = 102/370 (27%), Positives = 156/370 (42%), Gaps = 29/370 (7%)

Query: 265 QEKNWPCYECNRRFISSEQLQQHLNSHDEKLDVFSRTRGRGRGRGKRRFGP------GRR 318
           +EK + C EC R+FI   +L +H+  H  +   FS        R KR          G+R
Sbjct: 382 EEKPFSCGECGRKFIYKIKLDEHIRVHTGEKP-FSCPECNKSFRLKRSLKAHGLQHIGKR 440

Query: 319 PGRPPKFIRLEITSENGEKSDDGTQDLLHFPTKE---QFDEAEPATLNGLDQPEQTTIPI 375
           P + P+  R                +   FP  E   +F        +      Q   P 
Sbjct: 441 PFQCPECSRGFFWRNAMRAHQRLHSEQKPFPCAECGKRFTRPSKLACHTRVHDRQKEFPC 500

Query: 376 PQLPQ--ETQSSLEHEPETHTLHLQPQHEESVVPTQSTLTADDMRRAKRIRNAALQHLFI 433
            +  +    QS L    + HT             T+   +  +  R+ R R    +H  +
Sbjct: 501 GECKKTFSQQSRLTQHLKVHT-------------TEKPFSCAECGRSFRRRAHLTEHTRL 547

Query: 434 RKSFRPFKCLQCGKAFREKDKLDQHLRFHGREGNCPLTCDLCNKGFISSTSLESHMKLHS 493
                PF+C +C K+F  K  +  H R H  E   P  C  C+K +   + L  H++LHS
Sbjct: 548 HSGEEPFQCPECDKSFSWKASMKFHQRMHRDEK--PFACGECDKTYTHQSQLTEHLRLHS 605

Query: 494 DQKTYSCIFCPESFDRLDLLKDHVAIHINDGYFTCPTCKKRFPDFIQVKKHVRSFHSEKI 553
            +K Y C  C ++F     LK H+  H     F+C  C K F    ++ +H+R    EK 
Sbjct: 606 GEKPYQCPECEKTFRLKGNLKSHLLQHSGQKPFSCVMCGKSFTQQYRLTEHIRVHSGEKP 665

Query: 554 YQCTECDKAFCRPDKLRLHMLRHSDRKDFLCSTCGKQFKRKDKLREHMQRMHNPEREAKK 613
           +QC ECDK++C    L++H+ +HS  + F C  CGK F +K  L+ H+  +H+ ER    
Sbjct: 666 FQCPECDKSYCIRGSLKVHLYKHSGERPFQCPECGKGFLQKRSLKAHL-CLHSGERPF-S 723

Query: 614 ADRISRSKTF 623
            D   RS T+
Sbjct: 724 CDECGRSFTY 733



 Score =  137 bits (344), Expect = 7e-32
 Identities = 85/283 (30%), Positives = 121/283 (42%), Gaps = 28/283 (9%)

Query: 424 RNAALQHLFIRKSFRPFKCLQCGKAFREKDKLDQHLRFHGREGNCPLTCDLCNKGFISST 483
           RNA   H  +    +PF C +CGK F    KL  H R H R+   P  C  C K F   +
Sbjct: 454 RNAMRAHQRLHSEQKPFPCAECGKRFTRPSKLACHTRVHDRQKEFP--CGECKKTFSQQS 511

Query: 484 SLESHMKLHSDQKTYSCIFCPESFDRLDLLKDHVAIHINDGYFTCPTCKKRFPDFIQVKK 543
            L  H+K+H+ +K +SC  C  SF R   L +H  +H  +  F CP C K F     +K 
Sbjct: 512 RLTQHLKVHTTEKPFSCAECGRSFRRRAHLTEHTRLHSGEEPFQCPECDKSFSWKASMKF 571

Query: 544 HVRSFHSEKIYQCTECDKAFCRPDKLRLHMLRHSDRKDFLCSTCGKQFKRKDKLREHMQR 603
           H R    EK + C ECDK +    +L  H+  HS  K + C  C K F+ K  L+ H+ +
Sbjct: 572 HQRMHRDEKPFACGECDKTYTHQSQLTEHLRLHSGEKPYQCPECEKTFRLKGNLKSHLLQ 631

Query: 604 MHNPEREAKKADRISRSKTFKPRITSTDY-----DSFTFKCRLCMMGFRRRGMLVNHLSK 658
            H+ +   K    +   K+F  +   T++         F+C  C   +  RG L  HL K
Sbjct: 632 -HSGQ---KPFSCVMCGKSFTQQYRLTEHIRVHSGEKPFQCPECDKSYCIRGSLKVHLYK 687

Query: 659 RHPDMKIEEVPELTLPIIKPNRDYFCQYCDKVYKSASKRKAHI 701
              +                 R + C  C K +      KAH+
Sbjct: 688 HSGE-----------------RPFQCPECGKGFLQKRSLKAHL 713



 Score =  122 bits (307), Expect = 1e-27
 Identities = 57/172 (33%), Positives = 88/172 (51%), Gaps = 2/172 (1%)

Query: 430 HLFIRKSFRPFKCLQCGKAFREKDKLDQHLRFHGREGNCPLTCDLCNKGFISSTSLESHM 489
           H  + +  +PF C +C K +  + +L +HLR H   G  P  C  C K F    +L+SH+
Sbjct: 572 HQRMHRDEKPFACGECDKTYTHQSQLTEHLRLHS--GEKPYQCPECEKTFRLKGNLKSHL 629

Query: 490 KLHSDQKTYSCIFCPESFDRLDLLKDHVAIHINDGYFTCPTCKKRFPDFIQVKKHVRSFH 549
             HS QK +SC+ C +SF +   L +H+ +H  +  F CP C K +     +K H+    
Sbjct: 630 LQHSGQKPFSCVMCGKSFTQQYRLTEHIRVHSGEKPFQCPECDKSYCIRGSLKVHLYKHS 689

Query: 550 SEKIYQCTECDKAFCRPDKLRLHMLRHSDRKDFLCSTCGKQFKRKDKLREHM 601
            E+ +QC EC K F +   L+ H+  HS  + F C  CG+ F     L+ H+
Sbjct: 690 GERPFQCPECGKGFLQKRSLKAHLCLHSGERPFSCDECGRSFTYVGALKTHI 741



 Score =  122 bits (306), Expect = 2e-27
 Identities = 98/363 (26%), Positives = 150/363 (41%), Gaps = 42/363 (11%)

Query: 429 QHLFIRKSFRPFKCLQCGKAFREKDKLDQHLRFHGREGNCPLTCDLCNKGFISSTSLESH 488
           Q L  +K  + F+C +C K++  K  L  H   H   G  P  C  C+K F    +L+ H
Sbjct: 237 QRLLCQK--KRFQCSECEKSYFLKGSLVTHQVVH--TGQRPYPCPECDKTFRYRANLKKH 292

Query: 489 MKLHSDQKTYSCIFCPESFDRLDLLKDHVAIHINDGYFTCPTCKKRFPDFIQVKKHVRSF 548
           + LH  ++ + C  C  +F +   L +H+ +H  +  F CP C + F     +K H+   
Sbjct: 293 LCLHRGERPFCCGECGRAFVQQCELTEHLRLHSGEKPFQCPQCDRCFRLKRGMKVHLTQH 352

Query: 549 HSEKIYQCTECDKAFCRPDKLRLHMLRHSDRKDFLCSTCGKQFKRKDKLREHMQRMHNPE 608
             ++ + C EC ++F R   L+ H   HS+ K F C  CG++F  K KL EH+ R+H  E
Sbjct: 353 SGKRPFHCPECGRSFSRKAALKTHQRTHSEEKPFSCGECGRKFIYKIKLDEHI-RVHTGE 411

Query: 609 R-----EAKKADRISRSKTFKPRITSTDYDSFTFKCRLCMMGFRRRGMLVNHLSKRHPDM 663
           +     E  K+ R+ RS                F+C  C  GF  R  +  H  + H + 
Sbjct: 412 KPFSCPECNKSFRLKRSLKAH---GLQHIGKRPFQCPECSRGFFWRNAMRAH-QRLHSEQ 467

Query: 664 KIEEVPELTLPIIKPN------------RDYFCQYCDKVYKSASKRKAHIL-----KNHP 706
           K     E      +P+            +++ C  C K +   S+   H+      K   
Sbjct: 468 KPFPCAECGKRFTRPSKLACHTRVHDRQKEFPCGECKKTFSQQSRLTQHLKVHTTEKPFS 527

Query: 707 GAELPPSIRKLRPAGPGEPDPMLSTHTQLTGTIATPPVCCPHCSKQYSSKTKMVQHIRKK 766
            AE   S R+            L+ HT+L       P  CP C K +S K  M  H R  
Sbjct: 528 CAECGRSFRR---------RAHLTEHTRLHS--GEEPFQCPECDKSFSWKASMKFHQRMH 576

Query: 767 HPE 769
             E
Sbjct: 577 RDE 579



 Score =  100 bits (250), Expect = 5e-21
 Identities = 74/319 (23%), Positives = 129/319 (40%), Gaps = 33/319 (10%)

Query: 262 LREQEKNWPCYECNRRFISSEQLQQHLNSHDEKLDVFSRTRGRGRGRGKRRFGPGRRPGR 321
           L  ++K +PC EC +RF    +L  H   HD       R +    G  K+ F    +  R
Sbjct: 463 LHSEQKPFPCAECGKRFTRPSKLACHTRVHD-------RQKEFPCGECKKTFS---QQSR 512

Query: 322 PPKFIRLEITSENGEKSDDGTQDLLHFPTKEQFDEAEPATLNGLDQPEQTTIPIPQLPQE 381
             + +++  T +    ++ G         + +    E   L+  ++P Q   P       
Sbjct: 513 LTQHLKVHTTEKPFSCAECGRS------FRRRAHLTEHTRLHSGEEPFQC--PECDKSFS 564

Query: 382 TQSSLEHEPETHTLHLQPQHEESVVPTQSTLTADDMRRAKRIRNAALQHLFIRKSFRPFK 441
            ++S++     H               +      +  +    ++   +HL +    +P++
Sbjct: 565 WKASMKFHQRMHR-------------DEKPFACGECDKTYTHQSQLTEHLRLHSGEKPYQ 611

Query: 442 CLQCGKAFREKDKLDQHLRFHGREGNCPLTCDLCNKGFISSTSLESHMKLHSDQKTYSCI 501
           C +C K FR K  L  HL  H   G  P +C +C K F     L  H+++HS +K + C 
Sbjct: 612 CPECEKTFRLKGNLKSHLLQHS--GQKPFSCVMCGKSFTQQYRLTEHIRVHSGEKPFQCP 669

Query: 502 FCPESFDRLDLLKDHVAIHINDGYFTCPTCKKRFPDFIQVKKHVRSFHSEKIYQCTECDK 561
            C +S+     LK H+  H  +  F CP C K F     +K H+     E+ + C EC +
Sbjct: 670 ECDKSYCIRGSLKVHLYKHSGERPFQCPECGKGFLQKRSLKAHLCLHSGERPFSCDECGR 729

Query: 562 AFCRPDKLRLHMLRHSDRK 580
           +F     L+ H+  H+  K
Sbjct: 730 SFTYVGALKTHIAVHAKEK 748



 Score = 62.0 bits (149), Expect = 3e-09
 Identities = 63/269 (23%), Positives = 102/269 (37%), Gaps = 39/269 (14%)

Query: 262 LREQEKNWPCYECNRRFISSEQLQQHLNSHDEKLDVFSRTRGRGRGRGKR-----RFGPG 316
           + +++K +PC EC + F    +L QHL  H  +        GR   R        R   G
Sbjct: 491 VHDRQKEFPCGECKKTFSQQSRLTQHLKVHTTEKPFSCAECGRSFRRRAHLTEHTRLHSG 550

Query: 317 RRPGRPPKFIRLEITSENGEKSDDGTQDLLHFPTKE-------QFDEAEPATLNGLDQPE 369
             P + P+  +      + +      +D   F   E       Q    E   L+  ++P 
Sbjct: 551 EEPFQCPECDKSFSWKASMKFHQRMHRDEKPFACGECDKTYTHQSQLTEHLRLHSGEKPY 610

Query: 370 QTTIPIPQLPQETQSSLEHEPETHTLHLQPQHEESVVPTQSTLTAD-------------- 415
           Q     P+   E    L+   ++H L    Q   S V    + T                
Sbjct: 611 QC----PEC--EKTFRLKGNLKSHLLQHSGQKPFSCVMCGKSFTQQYRLTEHIRVHSGEK 664

Query: 416 -----DMRRAKRIRNAALQHLFIRKSFRPFKCLQCGKAFREKDKLDQHLRFHGREGNCPL 470
                +  ++  IR +   HL+     RPF+C +CGK F +K  L  HL  H   G  P 
Sbjct: 665 PFQCPECDKSYCIRGSLKVHLYKHSGERPFQCPECGKGFLQKRSLKAHLCLHS--GERPF 722

Query: 471 TCDLCNKGFISSTSLESHMKLHSDQKTYS 499
           +CD C + F    +L++H+ +H+ +K  S
Sbjct: 723 SCDECGRSFTYVGALKTHIAVHAKEKPSS 751


>gi|72384335 zinc finger protein 311 [Homo sapiens]
          Length = 666

 Score =  146 bits (368), Expect = 1e-34
 Identities = 93/307 (30%), Positives = 132/307 (42%), Gaps = 24/307 (7%)

Query: 416 DMRRAKRIRNAALQHLFIRKSFRPFKCLQCGKAFREKDKLDQHLRFHGREGNCPLTCDLC 475
           D  +A + RN    H  I    +P+KC  CGKAF+ K  L  H R H   G  P  C+ C
Sbjct: 335 DCGKAFKTRNRLCMHQLIHTGEKPYKCNCCGKAFQFKHSLTIHGRIH--TGEKPYECEEC 392

Query: 476 NKGFISSTSLESHMKLHSDQKTYSCIFCPESFDRLDLLKDHVAIHINDGYFTCPTCKKRF 535
            K F  S+ L  H+++H+ ++ Y C  C  +F R   L  H  IH  + ++ CP C K F
Sbjct: 393 GKAFSGSSDLTKHIRIHTGERPYECSKCGRAFSRSSDLSKHKRIHTREKHYGCPQCGKDF 452

Query: 536 PDFIQVKKHVRSFHSEKIYQCTECDKAFCRPDKLRLHMLRHSDRKDFLCSTCGKQFKRKD 595
               ++ KH R    EK Y+C EC KAF    K R H   H+  K + C  CGK F+ K 
Sbjct: 453 SIKAELTKHRRIHTEEKRYRCEECGKAFRHNCKRRAHEREHTGEKPYQCRDCGKTFQDKH 512

Query: 596 KLREHMQRMHNPEREAKKADRISRSKTFKPRITSTDYDSF-----TFKCRLCMMGFRRRG 650
            L  H QR+H  E+  K    +   K F  +   T++          KC +C M F    
Sbjct: 513 CLTIH-QRIHTGEKPYK---CLECGKAFSGKSNLTNHRRIHTGEKPHKCEVCGMAFHHSS 568

Query: 651 MLVNHLSKRHPDMKIEEVPELTLP------------IIKPNRDYFCQYCDKVYKSASKRK 698
           +L  H  + H   K     E                +    + Y C+ C K ++ +S   
Sbjct: 569 VLRQH-KRIHTGEKPYTCSECGTSFRQGSALIGHKRVHTGEKPYECEECGKAFRVSSNLT 627

Query: 699 AHILKNH 705
            H  + H
Sbjct: 628 GHKKRKH 634



 Score =  107 bits (268), Expect = 4e-23
 Identities = 88/309 (28%), Positives = 130/309 (42%), Gaps = 26/309 (8%)

Query: 472 CDLCNKGFISSTSLESHMKLHSDQKTYSCIFCPESFDRLDLLKDHVAIHINDGYFTCPTC 531
           C  C K F   + L  H ++HS +K + C  C ++F   + L  H  IH  +  F C  C
Sbjct: 249 CARCGKNFSWHSDLILHEQIHSGEKPHVCNECGKAFKTRNQLSMHRIIHTGEKPFNCTQC 308

Query: 532 KKRFPDFIQVKKHVRSFHSEKIYQCTECDKAFCRPDKLRLHMLRHSDRKDFLCSTCGKQF 591
            K F     + +H ++   EK ++C +C KAF   ++L +H L H+  K + C+ CGK F
Sbjct: 309 GKAFNSRSALCRHKKTHSGEKPHECRDCGKAFKTRNRLCMHQLIHTGEKPYKCNCCGKAF 368

Query: 592 KRKDKLREHMQRMHNPER-----EAKKADRISRSKTFKPRITSTDYDSFTFKCRLCMMGF 646
           + K  L  H  R+H  E+     E  KA   S   T   RI + +     ++C  C   F
Sbjct: 369 QFKHSLTIH-GRIHTGEKPYECEECGKAFSGSSDLTKHIRIHTGER---PYECSKCGRAF 424

Query: 647 RRRGMLVN----HLSKRH-------PDMKIEEVPELTLPIIKPNRDYFCQYCDKVYKSAS 695
            R   L      H  ++H        D  I+        I    + Y C+ C K ++   
Sbjct: 425 SRSSDLSKHKRIHTREKHYGCPQCGKDFSIKAELTKHRRIHTEEKRYRCEECGKAFRHNC 484

Query: 696 KRKAHILKNHPGAELPPSIRKLRPAGPGEPDPMLSTHTQLTGTIATPPVCCPHCSKQYSS 755
           KR+AH  + H G E P    + R  G    D    T  Q   T    P  C  C K +S 
Sbjct: 485 KRRAH-EREHTG-EKP---YQCRDCGKTFQDKHCLTIHQRIHT-GEKPYKCLECGKAFSG 538

Query: 756 KTKMVQHIR 764
           K+ +  H R
Sbjct: 539 KSNLTNHRR 547



 Score = 33.5 bits (75), Expect = 1.1
 Identities = 44/208 (21%), Positives = 78/208 (37%), Gaps = 9/208 (4%)

Query: 253 DISEEERKVLREQEKNWPCYECNRRFISSEQLQQHLNSHDEKLDVFSRTRGRG-RGRGKR 311
           D+S+ +R  +  +EK++ C +C + F    +L +H   H E+        G+  R   KR
Sbjct: 429 DLSKHKR--IHTREKHYGCPQCGKDFSIKAELTKHRRIHTEEKRYRCEECGKAFRHNCKR 486

Query: 312 RFGPGRRPGRPPKFIRLEITSENGEKSDDGTQDLLHFPTKE-QFDEAEPATLNGLDQPEQ 370
           R       G  P   R +      +K        +H   K  +  E   A     +    
Sbjct: 487 RAHEREHTGEKPYQCR-DCGKTFQDKHCLTIHQRIHTGEKPYKCLECGKAFSGKSNLTNH 545

Query: 371 TTIPIPQLPQETQSSLEHEPETHTLHLQPQHEESVVPTQSTLTADDMRRAKRIRNAALQH 430
             I   + P + +         H   +  QH+  +   +   T  +   + R  +A + H
Sbjct: 546 RRIHTGEKPHKCEVC---GMAFHHSSVLRQHKR-IHTGEKPYTCSECGTSFRQGSALIGH 601

Query: 431 LFIRKSFRPFKCLQCGKAFREKDKLDQH 458
             +    +P++C +CGKAFR    L  H
Sbjct: 602 KRVHTGEKPYECEECGKAFRVSSNLTGH 629


>gi|7662424 zinc finger protein 510 [Homo sapiens]
          Length = 683

 Score =  145 bits (367), Expect = 1e-34
 Identities = 112/424 (26%), Positives = 176/424 (41%), Gaps = 33/424 (7%)

Query: 266 EKNWPCYECNRRFISSEQLQQHLNSHDEKLDVFSRTRGRGRGRGKRRFGPGRRPGRPPKF 325
           E+ + C +  + F       +H +SH  +    S+     +   K+     RR G   K 
Sbjct: 251 EQAFECNKIGKAFNDKANCVKHNSSHTGETS--SKDDEFRKNCDKKTLFDHRRTGTGKKH 308

Query: 326 IRLEITSENGEKSDDGTQDLLHFPTKEQFDEAEPATLNGLDQPEQTTIPIPQLPQETQSS 385
           + L    ++ EKS     + L+   K    E  P+   G +   +  +  PQ     ++ 
Sbjct: 309 LHLNQCGKSFEKSTVEEYNKLNMGIKHY--ELNPS---GNNFNRKAHLTDPQTAVIEENP 363

Query: 386 LEHEPETHTLHLQPQHEESVVPTQSTLTADDMRRAKRIR--------------NAALQHL 431
           L     T T     ++ E+    Q+++     R    ++                 +QH 
Sbjct: 364 LVSNDRTQTWVKSSEYHENKKSYQTSVHRVRRRSHSMMKPYKCNECGKSFCQKGHLIQHQ 423

Query: 432 FIRKSFRPFKCLQCGKAFREKDKLDQHLRFHGREGNCPLTCDLCNKGFISSTSLESHMKL 491
                 +PF+C +CGK F +K  L  H R H  E   P  C+ C K F+  ++L  H ++
Sbjct: 424 RTHTGEKPFECSECGKTFSQKSHLSTHQRIHTAEK--PYKCNECGKTFVQKSTLRGHQRI 481

Query: 492 HSDQKTYSCIFCPESFDRLDLLKDHVAIHINDGYFTCPTCKKRFPDFIQVKKHVRSFHSE 551
           H+ +K Y C  C ++F +   L+DH  IH  +  F C  C K F     ++ H R+   E
Sbjct: 482 HTGEKPYECSECGKTFVQKSTLRDHHRIHTGEKSFQCNQCGKTFGQKSNLRIHQRTHTGE 541

Query: 552 KIYQCTECDKAFCRPDKLRLHMLRHSDRKDFLCSTCGKQFKRKDKLREHMQRMHNPEREA 611
           K YQC EC+K+F R D L  H   H+  K F C+ CGK F R   LR H QR+H  E+  
Sbjct: 542 KTYQCNECEKSFWRKDHLIQHQKTHTGEKPFKCNECGKTFARTSTLRVH-QRIHTGEKPF 600

Query: 612 KKADRISRSKTFKPRITSTDYDSF-----TFKCRLCMMGFRRRGMLVNHLSKRHPDMKIE 666
           K  +     K F  +   +D+         F+C  C   F ++  L  H  + H   K  
Sbjct: 601 KCNE---CGKKFVRKAILSDHQRIHTGEKPFQCNKCGKTFGQKSNLRIH-QRTHSGEKSY 656

Query: 667 EVPE 670
           E  E
Sbjct: 657 ECNE 660



 Score =  105 bits (263), Expect = 2e-22
 Identities = 60/179 (33%), Positives = 82/179 (45%), Gaps = 3/179 (1%)

Query: 430 HLFIRKSFRPFKCLQCGKAFREKDKLDQHLRFHGREGNCPLTCDLCNKGFISSTSLESHM 489
           H  I    + F+C QCGK F +K  L  H R H   G     C+ C K F     L  H 
Sbjct: 506 HHRIHTGEKSFQCNQCGKTFGQKSNLRIHQRTH--TGEKTYQCNECEKSFWRKDHLIQHQ 563

Query: 490 KLHSDQKTYSCIFCPESFDRLDLLKDHVAIHINDGYFTCPTCKKRFPDFIQVKKHVRSFH 549
           K H+ +K + C  C ++F R   L+ H  IH  +  F C  C K+F     +  H R   
Sbjct: 564 KTHTGEKPFKCNECGKTFARTSTLRVHQRIHTGEKPFKCNECGKKFVRKAILSDHQRIHT 623

Query: 550 SEKIYQCTECDKAFCRPDKLRLHMLRHSDRKDFLCSTCGKQFKRKD-KLREHMQRMHNP 607
            EK +QC +C K F +   LR+H   HS  K + C+  GK  K+    L + +Q   NP
Sbjct: 624 GEKPFQCNKCGKTFGQKSNLRIHQRTHSGEKSYECNEYGKLCKKSTLSLYQKIQGEGNP 682


>gi|55769561 zinc finger protein 21 isoform 2 [Homo sapiens]
          Length = 620

 Score =  145 bits (367), Expect = 1e-34
 Identities = 106/350 (30%), Positives = 154/350 (44%), Gaps = 26/350 (7%)

Query: 430 HLFIRKSFRPFKCLQCGKAFREKDKLDQHLRFHGREGNCPLTCDLCNKGFISSTSLESHM 489
           HL      RPF+C +CGKAFREK  +  H R H   G  P  C+ C K F   ++L  H 
Sbjct: 261 HLRTHTGERPFECPECGKAFREKSTVIIHYRTH--TGEKPYECNECGKAFTQKSNLIVHQ 318

Query: 490 KLHSDQKTYSCIFCPESF-DRLDLLKDHVAIHINDGYFTCPTCKKRFPDFIQVKKHVRSF 548
           K H+ +KTY C  C ESF  +LDL+  H + H       C  CKK F D   +  H R+ 
Sbjct: 319 KTHTGEKTYECTKCGESFIQKLDLIIHH-STHTGKKPHECNECKKTFSDKSTLIIHQRTH 377

Query: 549 HSEKIYQCTECDKAFCRPDKLRLHMLRHSDRKDFLCSTCGKQFKRKDKLREHMQRMHNPE 608
             EK ++CTEC K+F     L +H   H+  K + C  CGK F +K  L  H QR H+ E
Sbjct: 378 TGEKPHKCTECGKSFNEKSTLIVHQRTHTGEKPYECDVCGKTFTQKSNLGVH-QRTHSGE 436

Query: 609 R--EAKKADRISRSKTFKPRITSTDYDSFTFKCRLCMMGFRRRGMLVNHLSKRHPDMK-- 664
           +  E  + ++    K++             ++C  C   F ++  L+ H  + H + K  
Sbjct: 437 KPFECNECEKAFSQKSYLMLHQRGHTGEKPYECNECEKAFSQKSYLIIH-QRTHTEEKPY 495

Query: 665 --------IEEVPELTL--PIIKPNRDYFCQYCDKVYKSASKRKAHILKNHPGAELPPSI 714
                     E  +L +   I    + Y C  C K +   S+   H  + H G E P + 
Sbjct: 496 KCNECGKAFREKSKLIIHQRIHTGEKPYECPVCWKAFSQKSQLIIH-QRTHTG-EKPYAC 553

Query: 715 RKLRPAGPGEPDPMLSTHTQLTGTIATPPVCCPHCSKQYSSKTKMVQHIR 764
            +    G    +    T  Q T T    P  C  C K ++ K+ ++ H R
Sbjct: 554 TE---CGKAFREKSTFTVHQRTHT-GEKPYKCTECGKAFTQKSNLIVHQR 599



 Score =  123 bits (308), Expect = 1e-27
 Identities = 91/332 (27%), Positives = 129/332 (38%), Gaps = 34/332 (10%)

Query: 438 RPFKCLQCGKAFREKDKLDQHLRFHGREGNCPLTCDLCNKGFISSTSLESHMKLHSDQKT 497
           +P+   +CGK  R K  L  H R   + G  P  C  C K F   + L  H + H+ +K 
Sbjct: 185 KPYGYKECGKGLRRKKGLSLHQRI--KNGEKPFECTACRKTFSKKSHLIVHWRTHTGEKP 242

Query: 498 YSCIFCPESFDRLDLLKDHVAIHINDGYFTCPTCKKRFPDFIQVKKHVRSFHSEKIYQCT 557
           + C  C ++F +   L  H+  H  +  F CP C K F +   V  H R+   EK Y+C 
Sbjct: 243 FGCTECGKAFSQKSQLIIHLRTHTGERPFECPECGKAFREKSTVIIHYRTHTGEKPYECN 302

Query: 558 ECDKAFCRPDKLRLHMLRHSDRKDFLCSTCGKQFKRKDKLREHMQRMHNPEREAKKADRI 617
           EC KAF +   L +H   H+  K + C+ CG+ F +K  L  H    H+     K  +  
Sbjct: 303 ECGKAFTQKSNLIVHQKTHTGEKTYECTKCGESFIQKLDLIIH----HSTHTGKKPHECN 358

Query: 618 SRSKTFKPRIT-----STDYDSFTFKCRLCMMGFRRRGMLVNHLSKRHPDMKIEEVPELT 672
              KTF  + T      T       KC  C   F  +  L+ H  + H   K        
Sbjct: 359 ECKKTFSDKSTLIIHQRTHTGEKPHKCTECGKSFNEKSTLIVH-QRTHTGEK-------- 409

Query: 673 LPIIKPNRDYFCQYCDKVYKSASKRKAHILKNHPGAELPPSIRKLRPAGPGEPDPMLSTH 732
                    Y C  C K +   S    H  + H G E P    +   A   +   ML   
Sbjct: 410 --------PYECDVCGKTFTQKSNLGVH-QRTHSG-EKPFECNECEKAFSQKSYLMLHQR 459

Query: 733 TQLTGTIATPPVCCPHCSKQYSSKTKMVQHIR 764
               G     P  C  C K +S K+ ++ H R
Sbjct: 460 ----GHTGEKPYECNECEKAFSQKSYLIIHQR 487



 Score =  118 bits (295), Expect = 3e-26
 Identities = 62/168 (36%), Positives = 83/168 (49%), Gaps = 3/168 (1%)

Query: 438 RPFKCLQCGKAFREKDKLDQHLRFHGREGNCPLTCDLCNKGFISSTSLESHMKLHSDQKT 497
           +PF+C +C KAF +K  L  H R  G  G  P  C+ C K F   + L  H + H+++K 
Sbjct: 437 KPFECNECEKAFSQKSYLMLHQR--GHTGEKPYECNECEKAFSQKSYLIIHQRTHTEEKP 494

Query: 498 YSCIFCPESFDRLDLLKDHVAIHINDGYFTCPTCKKRFPDFIQVKKHVRSFHSEKIYQCT 557
           Y C  C ++F     L  H  IH  +  + CP C K F    Q+  H R+   EK Y CT
Sbjct: 495 YKCNECGKAFREKSKLIIHQRIHTGEKPYECPVCWKAFSQKSQLIIHQRTHTGEKPYACT 554

Query: 558 ECDKAFCRPDKLRLHMLRHSDRKDFLCSTCGKQFKRKDKLREHMQRMH 605
           EC KAF       +H   H+  K + C+ CGK F +K  L  H QR H
Sbjct: 555 ECGKAFREKSTFTVHQRTHTGEKPYKCTECGKAFTQKSNLIVH-QRTH 601



 Score = 98.2 bits (243), Expect = 3e-20
 Identities = 53/163 (32%), Positives = 77/163 (47%), Gaps = 7/163 (4%)

Query: 438 RPFKCLQCGKAFREKDKLDQHLRFHGREGNCPLTCDLCNKGFISSTSLESHMKLHSDQKT 497
           +P++C +C KAF +K  L  H R H  E   P  C+ C K F   + L  H ++H+ +K 
Sbjct: 465 KPYECNECEKAFSQKSYLIIHQRTHTEEK--PYKCNECGKAFREKSKLIIHQRIHTGEKP 522

Query: 498 YSCIFCPESFDRLDLLKDHVAIHINDGYFTCPTCKKRFPDFIQVKKHVRSFHSEKIYQCT 557
           Y C  C ++F +   L  H   H  +  + C  C K F +      H R+   EK Y+CT
Sbjct: 523 YECPVCWKAFSQKSQLIIHQRTHTGEKPYACTECGKAFREKSTFTVHQRTHTGEKPYKCT 582

Query: 558 ECDKAFCRPDKLRLHMLRHSDRKDFLCSTCGKQFKRKDKLREH 600
           EC KAF +   L +H   H+ +K       G+   RK K   H
Sbjct: 583 ECGKAFTQKSNLIVHQRTHAGKK-----AHGRGHTRKSKFMAH 620



 Score = 75.5 bits (184), Expect = 2e-13
 Identities = 76/296 (25%), Positives = 111/296 (37%), Gaps = 36/296 (12%)

Query: 490 KLHSDQKTYSCIFCPESFDRLDLLKDHVAIHINDGYFTCPTCKKRFPDFIQVKKHVRSFH 549
           K +   K Y    C +   R   L  H  I   +  F C  C+K F     +  H R+  
Sbjct: 179 KTNPGMKPYGYKECGKGLRRKKGLSLHQRIKNGEKPFECTACRKTFSKKSHLIVHWRTHT 238

Query: 550 SEKIYQCTECDKAFCRPDKLRLHMLRHSDRKDFLCSTCGKQFKRKDKLREHMQRMHNPER 609
            EK + CTEC KAF +  +L +H+  H+  + F C  CGK F+ K  +  H  R H  E+
Sbjct: 239 GEKPFGCTECGKAFSQKSQLIIHLRTHTGERPFECPECGKAFREKSTVIIH-YRTHTGEK 297

Query: 610 --EAKKADRISRSKTFKPRITSTDYDSFTFKCRLCMMGFRRRGMLVNHLSKRHPDMKIEE 667
             E  +  +    K+       T     T++C  C   F ++  L+ H S  H   K  E
Sbjct: 298 PYECNECGKAFTQKSNLIVHQKTHTGEKTYECTKCGESFIQKLDLIIHHS-THTGKKPHE 356

Query: 668 VPEL--------TLPIIK----PNRDYFCQYCDKVYKSASKRKAHILKNHPGAELPPSIR 715
             E         TL I +      + + C  C K +   S    H  + H G +      
Sbjct: 357 CNECKKTFSDKSTLIIHQRTHTGEKPHKCTECGKSFNEKSTLIVH-QRTHTGEK------ 409

Query: 716 KLRPAGPGEPDPMLSTHTQLTGT-------IATPPVCCPHCSKQYSSKTKMVQHIR 764
                 P E D    T TQ +             P  C  C K +S K+ ++ H R
Sbjct: 410 ------PYECDVCGKTFTQKSNLGVHQRTHSGEKPFECNECEKAFSQKSYLMLHQR 459



 Score = 35.4 bits (80), Expect = 0.28
 Identities = 16/44 (36%), Positives = 23/44 (52%)

Query: 419 RAKRIRNAALQHLFIRKSFRPFKCLQCGKAFREKDKLDQHLRFH 462
           +A R ++    H       +P+KC +CGKAF +K  L  H R H
Sbjct: 558 KAFREKSTFTVHQRTHTGEKPYKCTECGKAFTQKSNLIVHQRTH 601


>gi|55769559 zinc finger protein 21 isoform 1 [Homo sapiens]
          Length = 639

 Score =  145 bits (367), Expect = 1e-34
 Identities = 106/350 (30%), Positives = 154/350 (44%), Gaps = 26/350 (7%)

Query: 430 HLFIRKSFRPFKCLQCGKAFREKDKLDQHLRFHGREGNCPLTCDLCNKGFISSTSLESHM 489
           HL      RPF+C +CGKAFREK  +  H R H   G  P  C+ C K F   ++L  H 
Sbjct: 280 HLRTHTGERPFECPECGKAFREKSTVIIHYRTH--TGEKPYECNECGKAFTQKSNLIVHQ 337

Query: 490 KLHSDQKTYSCIFCPESF-DRLDLLKDHVAIHINDGYFTCPTCKKRFPDFIQVKKHVRSF 548
           K H+ +KTY C  C ESF  +LDL+  H + H       C  CKK F D   +  H R+ 
Sbjct: 338 KTHTGEKTYECTKCGESFIQKLDLIIHH-STHTGKKPHECNECKKTFSDKSTLIIHQRTH 396

Query: 549 HSEKIYQCTECDKAFCRPDKLRLHMLRHSDRKDFLCSTCGKQFKRKDKLREHMQRMHNPE 608
             EK ++CTEC K+F     L +H   H+  K + C  CGK F +K  L  H QR H+ E
Sbjct: 397 TGEKPHKCTECGKSFNEKSTLIVHQRTHTGEKPYECDVCGKTFTQKSNLGVH-QRTHSGE 455

Query: 609 R--EAKKADRISRSKTFKPRITSTDYDSFTFKCRLCMMGFRRRGMLVNHLSKRHPDMK-- 664
           +  E  + ++    K++             ++C  C   F ++  L+ H  + H + K  
Sbjct: 456 KPFECNECEKAFSQKSYLMLHQRGHTGEKPYECNECEKAFSQKSYLIIH-QRTHTEEKPY 514

Query: 665 --------IEEVPELTL--PIIKPNRDYFCQYCDKVYKSASKRKAHILKNHPGAELPPSI 714
                     E  +L +   I    + Y C  C K +   S+   H  + H G E P + 
Sbjct: 515 KCNECGKAFREKSKLIIHQRIHTGEKPYECPVCWKAFSQKSQLIIH-QRTHTG-EKPYAC 572

Query: 715 RKLRPAGPGEPDPMLSTHTQLTGTIATPPVCCPHCSKQYSSKTKMVQHIR 764
            +    G    +    T  Q T T    P  C  C K ++ K+ ++ H R
Sbjct: 573 TE---CGKAFREKSTFTVHQRTHT-GEKPYKCTECGKAFTQKSNLIVHQR 618



 Score =  123 bits (308), Expect = 1e-27
 Identities = 91/332 (27%), Positives = 129/332 (38%), Gaps = 34/332 (10%)

Query: 438 RPFKCLQCGKAFREKDKLDQHLRFHGREGNCPLTCDLCNKGFISSTSLESHMKLHSDQKT 497
           +P+   +CGK  R K  L  H R   + G  P  C  C K F   + L  H + H+ +K 
Sbjct: 204 KPYGYKECGKGLRRKKGLSLHQRI--KNGEKPFECTACRKTFSKKSHLIVHWRTHTGEKP 261

Query: 498 YSCIFCPESFDRLDLLKDHVAIHINDGYFTCPTCKKRFPDFIQVKKHVRSFHSEKIYQCT 557
           + C  C ++F +   L  H+  H  +  F CP C K F +   V  H R+   EK Y+C 
Sbjct: 262 FGCTECGKAFSQKSQLIIHLRTHTGERPFECPECGKAFREKSTVIIHYRTHTGEKPYECN 321

Query: 558 ECDKAFCRPDKLRLHMLRHSDRKDFLCSTCGKQFKRKDKLREHMQRMHNPEREAKKADRI 617
           EC KAF +   L +H   H+  K + C+ CG+ F +K  L  H    H+     K  +  
Sbjct: 322 ECGKAFTQKSNLIVHQKTHTGEKTYECTKCGESFIQKLDLIIH----HSTHTGKKPHECN 377

Query: 618 SRSKTFKPRIT-----STDYDSFTFKCRLCMMGFRRRGMLVNHLSKRHPDMKIEEVPELT 672
              KTF  + T      T       KC  C   F  +  L+ H  + H   K        
Sbjct: 378 ECKKTFSDKSTLIIHQRTHTGEKPHKCTECGKSFNEKSTLIVH-QRTHTGEK-------- 428

Query: 673 LPIIKPNRDYFCQYCDKVYKSASKRKAHILKNHPGAELPPSIRKLRPAGPGEPDPMLSTH 732
                    Y C  C K +   S    H  + H G E P    +   A   +   ML   
Sbjct: 429 --------PYECDVCGKTFTQKSNLGVH-QRTHSG-EKPFECNECEKAFSQKSYLMLHQR 478

Query: 733 TQLTGTIATPPVCCPHCSKQYSSKTKMVQHIR 764
               G     P  C  C K +S K+ ++ H R
Sbjct: 479 ----GHTGEKPYECNECEKAFSQKSYLIIHQR 506



 Score =  118 bits (295), Expect = 3e-26
 Identities = 62/168 (36%), Positives = 83/168 (49%), Gaps = 3/168 (1%)

Query: 438 RPFKCLQCGKAFREKDKLDQHLRFHGREGNCPLTCDLCNKGFISSTSLESHMKLHSDQKT 497
           +PF+C +C KAF +K  L  H R  G  G  P  C+ C K F   + L  H + H+++K 
Sbjct: 456 KPFECNECEKAFSQKSYLMLHQR--GHTGEKPYECNECEKAFSQKSYLIIHQRTHTEEKP 513

Query: 498 YSCIFCPESFDRLDLLKDHVAIHINDGYFTCPTCKKRFPDFIQVKKHVRSFHSEKIYQCT 557
           Y C  C ++F     L  H  IH  +  + CP C K F    Q+  H R+   EK Y CT
Sbjct: 514 YKCNECGKAFREKSKLIIHQRIHTGEKPYECPVCWKAFSQKSQLIIHQRTHTGEKPYACT 573

Query: 558 ECDKAFCRPDKLRLHMLRHSDRKDFLCSTCGKQFKRKDKLREHMQRMH 605
           EC KAF       +H   H+  K + C+ CGK F +K  L  H QR H
Sbjct: 574 ECGKAFREKSTFTVHQRTHTGEKPYKCTECGKAFTQKSNLIVH-QRTH 620



 Score = 98.2 bits (243), Expect = 3e-20
 Identities = 53/163 (32%), Positives = 77/163 (47%), Gaps = 7/163 (4%)

Query: 438 RPFKCLQCGKAFREKDKLDQHLRFHGREGNCPLTCDLCNKGFISSTSLESHMKLHSDQKT 497
           +P++C +C KAF +K  L  H R H  E   P  C+ C K F   + L  H ++H+ +K 
Sbjct: 484 KPYECNECEKAFSQKSYLIIHQRTHTEEK--PYKCNECGKAFREKSKLIIHQRIHTGEKP 541

Query: 498 YSCIFCPESFDRLDLLKDHVAIHINDGYFTCPTCKKRFPDFIQVKKHVRSFHSEKIYQCT 557
           Y C  C ++F +   L  H   H  +  + C  C K F +      H R+   EK Y+CT
Sbjct: 542 YECPVCWKAFSQKSQLIIHQRTHTGEKPYACTECGKAFREKSTFTVHQRTHTGEKPYKCT 601

Query: 558 ECDKAFCRPDKLRLHMLRHSDRKDFLCSTCGKQFKRKDKLREH 600
           EC KAF +   L +H   H+ +K       G+   RK K   H
Sbjct: 602 ECGKAFTQKSNLIVHQRTHAGKK-----AHGRGHTRKSKFMAH 639



 Score = 75.5 bits (184), Expect = 2e-13
 Identities = 76/296 (25%), Positives = 111/296 (37%), Gaps = 36/296 (12%)

Query: 490 KLHSDQKTYSCIFCPESFDRLDLLKDHVAIHINDGYFTCPTCKKRFPDFIQVKKHVRSFH 549
           K +   K Y    C +   R   L  H  I   +  F C  C+K F     +  H R+  
Sbjct: 198 KTNPGMKPYGYKECGKGLRRKKGLSLHQRIKNGEKPFECTACRKTFSKKSHLIVHWRTHT 257

Query: 550 SEKIYQCTECDKAFCRPDKLRLHMLRHSDRKDFLCSTCGKQFKRKDKLREHMQRMHNPER 609
            EK + CTEC KAF +  +L +H+  H+  + F C  CGK F+ K  +  H  R H  E+
Sbjct: 258 GEKPFGCTECGKAFSQKSQLIIHLRTHTGERPFECPECGKAFREKSTVIIH-YRTHTGEK 316

Query: 610 --EAKKADRISRSKTFKPRITSTDYDSFTFKCRLCMMGFRRRGMLVNHLSKRHPDMKIEE 667
             E  +  +    K+       T     T++C  C   F ++  L+ H S  H   K  E
Sbjct: 317 PYECNECGKAFTQKSNLIVHQKTHTGEKTYECTKCGESFIQKLDLIIHHS-THTGKKPHE 375

Query: 668 VPEL--------TLPIIK----PNRDYFCQYCDKVYKSASKRKAHILKNHPGAELPPSIR 715
             E         TL I +      + + C  C K +   S    H  + H G +      
Sbjct: 376 CNECKKTFSDKSTLIIHQRTHTGEKPHKCTECGKSFNEKSTLIVH-QRTHTGEK------ 428

Query: 716 KLRPAGPGEPDPMLSTHTQLTGT-------IATPPVCCPHCSKQYSSKTKMVQHIR 764
                 P E D    T TQ +             P  C  C K +S K+ ++ H R
Sbjct: 429 ------PYECDVCGKTFTQKSNLGVHQRTHSGEKPFECNECEKAFSQKSYLMLHQR 478



 Score = 35.4 bits (80), Expect = 0.28
 Identities = 16/44 (36%), Positives = 23/44 (52%)

Query: 419 RAKRIRNAALQHLFIRKSFRPFKCLQCGKAFREKDKLDQHLRFH 462
           +A R ++    H       +P+KC +CGKAF +K  L  H R H
Sbjct: 577 KAFREKSTFTVHQRTHTGEKPYKCTECGKAFTQKSNLIVHQRTH 620


>gi|34303941 zinc finger protein 567 [Homo sapiens]
          Length = 616

 Score =  145 bits (367), Expect = 1e-34
 Identities = 123/532 (23%), Positives = 209/532 (39%), Gaps = 42/532 (7%)

Query: 254 ISEEERKVLREQEKNWP-CYECNRRFISSEQLQQHLNSHDEKLDVFSRTRGRGRGRGKRR 312
           +S   +K+++E+ K +   +   +  ++S+ L    ++H   L   S          ++R
Sbjct: 68  VSINHKKLVKEKSKIYEKTFTLGKNPVNSKNLPPEYDTHGRILKNVSELIISNLNPARKR 127

Query: 313 FGPGRRPGRPPKFIRLEITSENGEKSDDGTQDLLHFPTKEQFDEAE-PATLNGLDQPEQT 371
                  G+     + E T    +  +   +   H     Q+ + E PA   G +  E++
Sbjct: 128 LSEYNGYGKSLLSTKQETTHPEVKSHNQSARAFSHNEVLMQYQKTETPAQSFGYNDCEKS 187

Query: 372 TIPIPQL-----PQETQSSLEHEPETHTLHLQPQHEESVVPTQSTLTADDMRRAKRIRNA 426
            +    L     P + ++   +  +    +++ +H           T ++  ++   ++ 
Sbjct: 188 FLQRGGLITHSRPYKGENPSVYNKKRRATNIEKKH-----------TCNECGKSFCRKSV 236

Query: 427 ALQHLFIRKSFRPFKCLQCGKAFREKDKLDQHLRFHGREGNCPLTCDLCNKGFISSTSLE 486
            + H  I    +P++C QCG AFR K  L  H R H   G  P  C+ C K F   T+L 
Sbjct: 237 LILHQGIHSEEKPYQCHQCGNAFRRKSYLIDHQRTH--TGEKPFVCNECGKSFRLKTALT 294

Query: 487 SHMKLHSDQKTYSCIFCPESFDRLDLLKDHVAIHINDGYFTCPTCKKRFPDFIQVKKHVR 546
            H + H+ +K+Y C+ C  +F     L  H   H  +  + C  C K F     +  H R
Sbjct: 295 DHQRTHTGEKSYECLQCRNAFRLKSHLIRHQRTHTGEKPYECNDCGKSFRQKTTLSLHQR 354

Query: 547 SFHSEKIYQCTECDKAFCRPDKLRLHMLRHSDRKDFLCSTCGKQFKRKDKLREHMQRMHN 606
               EK Y C EC K+F +   L +H   H+  K ++C+ CGK F +K  L  H ++ HN
Sbjct: 355 IHTGEKPYICKECGKSFHQKANLTVHQRTHTGEKPYICNECGKSFSQKTTLALH-EKTHN 413

Query: 607 PERE--AKKADRISRSKTFKPRITSTDYDSFTFKCRLCMMGFRRRGMLVNHLSKRHPDMK 664
            E+     +  +  R KT       T     +++C  C   FR +  L++H  + H   K
Sbjct: 414 EEKPYICSECGKSFRQKTTLVAHQRTHTGEKSYECPHCGKAFRMKSYLIDH-HRTHTGEK 472

Query: 665 IEEVPE------------LTLPIIKPNRDYFCQYCDKVYKSASKRKAHILKNHPGAELPP 712
             E  E            L   I    + Y C  C K ++  +    H  K H G +   
Sbjct: 473 PYECNECGKSFSQKTNLNLHQRIHTGEKPYVCNECGKSFRQKATLTVH-QKIHTGQK--- 528

Query: 713 SIRKLRPAGPGEPDPMLSTHTQLTGTIATPPVCCPHCSKQYSSKTKMVQHIR 764
              +    G          H Q T T    P  C  C K +  KT ++ H R
Sbjct: 529 -SYECPQCGKAFSRKSYLIHHQRTHT-GEKPYKCSECGKCFRQKTNLIVHQR 578



 Score =  122 bits (305), Expect = 2e-27
 Identities = 94/351 (26%), Positives = 142/351 (40%), Gaps = 22/351 (6%)

Query: 266 EKNWPCYECNRRFISSEQLQQHLNSHD-----EKLDVFSRTRGRGRGRGKRRFGPGRRP- 319
           EK + C EC + F     L  H  +H      E L   +  R +      +R   G +P 
Sbjct: 275 EKPFVCNECGKSFRLKTALTDHQRTHTGEKSYECLQCRNAFRLKSHLIRHQRTHTGEKPY 334

Query: 320 --GRPPKFIRLEITSENGEKSDDGTQDLLHFPTKEQFDEAEPATLNGLDQPEQTTIPIPQ 377
                 K  R + T    ++   G +  +     + F +    T++      +     P 
Sbjct: 335 ECNDCGKSFRQKTTLSLHQRIHTGEKPYICKECGKSFHQKANLTVHQRTHTGEK----PY 390

Query: 378 LPQETQSSLEHEPETHTLHLQPQHEESVVPTQSTLTADDMRRAKRIRNAALQHLFIRKSF 437
           +  E   S   +  T  LH +  +EE            +  ++ R +   + H       
Sbjct: 391 ICNECGKSFSQKT-TLALHEKTHNEEK------PYICSECGKSFRQKTTLVAHQRTHTGE 443

Query: 438 RPFKCLQCGKAFREKDKLDQHLRFHGREGNCPLTCDLCNKGFISSTSLESHMKLHSDQKT 497
           + ++C  CGKAFR K  L  H R H   G  P  C+ C K F   T+L  H ++H+ +K 
Sbjct: 444 KSYECPHCGKAFRMKSYLIDHHRTH--TGEKPYECNECGKSFSQKTNLNLHQRIHTGEKP 501

Query: 498 YSCIFCPESFDRLDLLKDHVAIHINDGYFTCPTCKKRFPDFIQVKKHVRSFHSEKIYQCT 557
           Y C  C +SF +   L  H  IH     + CP C K F     +  H R+   EK Y+C+
Sbjct: 502 YVCNECGKSFRQKATLTVHQKIHTGQKSYECPQCGKAFSRKSYLIHHQRTHTGEKPYKCS 561

Query: 558 ECDKAFCRPDKLRLHMLRHSDRKDFLCSTCGKQFKRKDKLREHMQRMHNPE 608
           EC K F +   L +H   H+  K ++C+ CGK F  K  L  H QR H  E
Sbjct: 562 ECGKCFRQKTNLIVHQRTHTGEKPYVCNECGKSFSYKRNLIVH-QRTHKGE 611



 Score = 65.9 bits (159), Expect = 2e-10
 Identities = 37/124 (29%), Positives = 53/124 (42%), Gaps = 2/124 (1%)

Query: 430 HLFIRKSFRPFKCLQCGKAFREKDKLDQHLRFHGREGNCPLTCDLCNKGFISSTSLESHM 489
           H  I    +P+ C +CGK+FR+K  L  H + H   G     C  C K F   + L  H 
Sbjct: 492 HQRIHTGEKPYVCNECGKSFRQKATLTVHQKIH--TGQKSYECPQCGKAFSRKSYLIHHQ 549

Query: 490 KLHSDQKTYSCIFCPESFDRLDLLKDHVAIHINDGYFTCPTCKKRFPDFIQVKKHVRSFH 549
           + H+ +K Y C  C + F +   L  H   H  +  + C  C K F     +  H R+  
Sbjct: 550 RTHTGEKPYKCSECGKCFRQKTNLIVHQRTHTGEKPYVCNECGKSFSYKRNLIVHQRTHK 609

Query: 550 SEKI 553
            E I
Sbjct: 610 GENI 613


>gi|22095393 zinc finger protein 420 [Homo sapiens]
          Length = 688

 Score =  144 bits (363), Expect = 4e-34
 Identities = 103/360 (28%), Positives = 154/360 (42%), Gaps = 30/360 (8%)

Query: 408 TQSTLTADDMRRAKRIRNAALQHLFIRKSFRPFKCLQCGKAFREKDKLDQHLRFHGREGN 467
           T+      +  +A R  +   QH  I    +P++C QCGKAF    +L  H R H   G 
Sbjct: 135 TEKPYKCKECGKAFRRASHLTQHQSIHTGEKPYECKQCGKAFSRDSQLSLHQRLH--TGE 192

Query: 468 CPLTCDLCNKGFISSTSLESHMKLHSDQKTYSCIFCPESFDRLDLLKDHVAIHINDGYFT 527
            P  C  C K F  S+ L  H ++H+ +K Y C  C ++F R   L  H  +H  +  + 
Sbjct: 193 KPYACKECGKAFTQSSQLILHHRIHTGEKPYKCEECGKAFIRSSQLTRHQKVHTGEKPYE 252

Query: 528 CPTCKKRFPDFIQVKKHVRSFHSEKIYQCTECDKAFCRPDKLRLHMLRHSDRKDFLCSTC 587
           C  C K F    Q+  H R    EK+Y+C EC K F +  +L LH   H+  K + C  C
Sbjct: 253 CKECGKAFTQNSQLTLHQRLHTGEKLYECKECRKVFTQLSQLILHKRIHTGEKPYECKEC 312

Query: 588 GKQFKRKDKLREHMQRMHNPER--EAKKADRISRSKTFKPRITSTDYDSFTFKCRLCMMG 645
           GK F    +L +H Q++HN E+  E K+  R     +   +          +KC  C   
Sbjct: 313 GKAFICGSQLSQH-QKIHNGEKPYECKECGRAFIRGSLLMQHQRIHTGEKPYKCEECGKA 371

Query: 646 FRRRGMLVNHLSKRHPDMKIEEVPELTLPIIKPNRDYFCQYCDKVYKSASKRKAHILKNH 705
           F R   L  H  + H + K                 Y C+ C K++   S+   H  + H
Sbjct: 372 FIRGSQLTQH-QRIHTNEK----------------PYECKECGKMFSHGSQLTQH-QRIH 413

Query: 706 PGAELPPSIRKLRPAGPGEPDPMLSTHTQL-TGTIATPPVCCPHCSKQYSSKTKMVQHIR 764
            G E P   ++   A       +L+ H ++ TG     P  C  C K +S  +++ QH R
Sbjct: 414 TG-EKPYQCKECGKA--FNRGSLLTRHQRIHTG---EKPYECKECGKTFSRGSELTQHER 467



 Score =  143 bits (361), Expect = 7e-34
 Identities = 140/560 (25%), Positives = 213/560 (38%), Gaps = 93/560 (16%)

Query: 266 EKNWPCYECNRRFISSEQLQQHLNSHDEKLDVFSRTRGRGRGRGKR-----RFGPGRRPG 320
           EK + C EC + F  +  L QH + H  +     +  G+   R  +     R   G +P 
Sbjct: 136 EKPYKCKECGKAFRRASHLTQHQSIHTGEKPYECKQCGKAFSRDSQLSLHQRLHTGEKP- 194

Query: 321 RPPKFIRLEITSENGEKSDDGTQDLLH--FPTKEQ---FDEAEPATLNGLDQPEQTTIPI 375
                       E G+     +Q +LH    T E+    +E   A +          +  
Sbjct: 195 --------YACKECGKAFTQSSQLILHHRIHTGEKPYKCEECGKAFIRSSQLTRHQKVHT 246

Query: 376 PQLPQETQSSLEHEPETHTLHLQPQHEESVVPTQSTLTADDMRRAKRIRNAALQ------ 429
            + P E +   +   +   L L           Q   T + +   K  R    Q      
Sbjct: 247 GEKPYECKECGKAFTQNSQLTLH----------QRLHTGEKLYECKECRKVFTQLSQLIL 296

Query: 430 HLFIRKSFRPFKCLQCGKAFREKDKLDQHLRFHGREGNCPLTCDLCNKGFISSTSLESHM 489
           H  I    +P++C +CGKAF    +L QH + H   G  P  C  C + FI  + L  H 
Sbjct: 297 HKRIHTGEKPYECKECGKAFICGSQLSQHQKIHN--GEKPYECKECGRAFIRGSLLMQHQ 354

Query: 490 KLHSDQKTYSCIFCPESFDRLDLLKDHVAIHINDGYFTCPTCKKRFPDFIQVKKHVRSFH 549
           ++H+ +K Y C  C ++F R   L  H  IH N+  + C  C K F    Q+ +H R   
Sbjct: 355 RIHTGEKPYKCEECGKAFIRGSQLTQHQRIHTNEKPYECKECGKMFSHGSQLTQHQRIHT 414

Query: 550 SEKIYQCTECDKAFCRPDKLRLHMLRHSDRKDFLCSTCGKQFKRKDKLREHMQRMHNPE- 608
            EK YQC EC KAF R   L  H   H+  K + C  CGK F R  +L +H +R+H  E 
Sbjct: 415 GEKPYQCKECGKAFNRGSLLTRHQRIHTGEKPYECKECGKTFSRGSELTQH-ERIHTGEK 473

Query: 609 ----REAKKADRISRSKTFKPRITSTDYDSFTFKCRLCMMGFRR---------------- 648
               +E  K+       T   RI + +     ++C+ C M F +                
Sbjct: 474 PYECKECGKSFIRGSQLTQHQRIHTGEK---PYECKECRMAFTQSSHLSQHQRLHTGEKP 530

Query: 649 -----------RGMLVNHLSKRHPDMKIEEVPELTLPIIKPN------------RDYFCQ 685
                      RG+L+    + H   K  +  E     I+ +            + Y C+
Sbjct: 531 YVCNECGKAFARGLLLIQHQRIHTGEKPYQCKECGKAFIRGSQLTQHQRIHTGEKPYECK 590

Query: 686 YCDKVYKSASKRKAHILKNHPGAELPPSIRKLRPAGPGEPDPMLSTHTQL-TGTIATPPV 744
            C K +   S+   H  + H G E P   R+ R A        LS H ++ TG     P 
Sbjct: 591 ECGKAFSHGSQLTLH-QRIHTG-EKPYECRECRKA--FTQSSHLSRHQRIHTG---EKPY 643

Query: 745 CCPHCSKQYSSKTKMVQHIR 764
            C  C K ++  +++ QH R
Sbjct: 644 QCKECGKAFTRGSQLTQHQR 663



 Score =  128 bits (321), Expect = 3e-29
 Identities = 104/379 (27%), Positives = 152/379 (40%), Gaps = 36/379 (9%)

Query: 260 KVLREQEKNWPCYECNRRFISSEQLQQHLNSHDEKLDVFSRTRGRGRGRGK-----RRFG 314
           K +   EK + C EC + FI   QL QH   H+ +     +  GR   RG      +R  
Sbjct: 298 KRIHTGEKPYECKECGKAFICGSQLSQHQKIHNGEKPYECKECGRAFIRGSLLMQHQRIH 357

Query: 315 PGRRPGRPPK----FIR-LEITS--------------ENGEKSDDGTQDLLH--FPTKE- 352
            G +P +  +    FIR  ++T               E G+    G+Q   H    T E 
Sbjct: 358 TGEKPYKCEECGKAFIRGSQLTQHQRIHTNEKPYECKECGKMFSHGSQLTQHQRIHTGEK 417

Query: 353 --QFDEAEPATLNGLDQPEQTTIPIPQLPQETQSSLEHEPETHTLHLQPQHEESVVPTQS 410
             Q  E   A   G        I   + P E +       +T +   +    E +   + 
Sbjct: 418 PYQCKECGKAFNRGSLLTRHQRIHTGEKPYECKEC----GKTFSRGSELTQHERIHTGEK 473

Query: 411 TLTADDMRRAKRIRNAALQHLFIRKSFRPFKCLQCGKAFREKDKLDQHLRFHGREGNCPL 470
                +  ++    +   QH  I    +P++C +C  AF +   L QH R H   G  P 
Sbjct: 474 PYECKECGKSFIRGSQLTQHQRIHTGEKPYECKECRMAFTQSSHLSQHQRLH--TGEKPY 531

Query: 471 TCDLCNKGFISSTSLESHMKLHSDQKTYSCIFCPESFDRLDLLKDHVAIHINDGYFTCPT 530
            C+ C K F     L  H ++H+ +K Y C  C ++F R   L  H  IH  +  + C  
Sbjct: 532 VCNECGKAFARGLLLIQHQRIHTGEKPYQCKECGKAFIRGSQLTQHQRIHTGEKPYECKE 591

Query: 531 CKKRFPDFIQVKKHVRSFHSEKIYQCTECDKAFCRPDKLRLHMLRHSDRKDFLCSTCGKQ 590
           C K F    Q+  H R    EK Y+C EC KAF +   L  H   H+  K + C  CGK 
Sbjct: 592 CGKAFSHGSQLTLHQRIHTGEKPYECRECRKAFTQSSHLSRHQRIHTGEKPYQCKECGKA 651

Query: 591 FKRKDKLREHMQRMHNPER 609
           F R  +L +H QR+H  E+
Sbjct: 652 FTRGSQLTQH-QRIHISEK 669



 Score =  116 bits (291), Expect = 9e-26
 Identities = 88/336 (26%), Positives = 129/336 (38%), Gaps = 25/336 (7%)

Query: 266 EKNWPCYECNRRFISSEQLQQHLNSHDEKLDVFSRTRGRGRGRGKR-----RFGPGRRPG 320
           EK + C EC + FI   QL QH   H  +     +  G+    G +     R   G +P 
Sbjct: 360 EKPYKCEECGKAFIRGSQLTQHQRIHTNEKPYECKECGKMFSHGSQLTQHQRIHTGEKPY 419

Query: 321 RPPKFIRLEITSENGEKSDDGT----QDLLHFPTKE-QFDEAEPATLNGLDQPEQTTIPI 375
           +           E G+  + G+       +H   K  +  E       G +  +   I  
Sbjct: 420 Q---------CKECGKAFNRGSLLTRHQRIHTGEKPYECKECGKTFSRGSELTQHERIHT 470

Query: 376 PQLPQETQSSLEHEPETHTLHLQPQHEESVVPTQSTLTADDMRRAKRIRNAALQHLFIRK 435
            + P E +       ++     Q    + +   +      + R A    +   QH  +  
Sbjct: 471 GEKPYECKEC----GKSFIRGSQLTQHQRIHTGEKPYECKECRMAFTQSSHLSQHQRLHT 526

Query: 436 SFRPFKCLQCGKAFREKDKLDQHLRFHGREGNCPLTCDLCNKGFISSTSLESHMKLHSDQ 495
             +P+ C +CGKAF     L QH R H   G  P  C  C K FI  + L  H ++H+ +
Sbjct: 527 GEKPYVCNECGKAFARGLLLIQHQRIH--TGEKPYQCKECGKAFIRGSQLTQHQRIHTGE 584

Query: 496 KTYSCIFCPESFDRLDLLKDHVAIHINDGYFTCPTCKKRFPDFIQVKKHVRSFHSEKIYQ 555
           K Y C  C ++F     L  H  IH  +  + C  C+K F     + +H R    EK YQ
Sbjct: 585 KPYECKECGKAFSHGSQLTLHQRIHTGEKPYECRECRKAFTQSSHLSRHQRIHTGEKPYQ 644

Query: 556 CTECDKAFCRPDKLRLHMLRHSDRKDFLCSTCGKQF 591
           C EC KAF R  +L  H   H   K F    CG  F
Sbjct: 645 CKECGKAFTRGSQLTQHQRIHISEKSFEYKECGIDF 680



 Score =  111 bits (278), Expect = 3e-24
 Identities = 89/334 (26%), Positives = 130/334 (38%), Gaps = 32/334 (9%)

Query: 449 FREKDKLDQHLRFHGREGNCPLTCDLCNKGFISSTSLESHMKLHSDQKTYSCIFCPESFD 508
           F +   L QH R H  E   P  C  C K F  ++ L  H  +H+ +K Y C  C ++F 
Sbjct: 120 FNQHTYLSQHSRCHSTEK--PYKCKECGKAFRRASHLTQHQSIHTGEKPYECKQCGKAFS 177

Query: 509 RLDLLKDHVAIHINDGYFTCPTCKKRFPDFIQVKKHVRSFHSEKIYQCTECDKAFCRPDK 568
           R   L  H  +H  +  + C  C K F    Q+  H R    EK Y+C EC KAF R  +
Sbjct: 178 RDSQLSLHQRLHTGEKPYACKECGKAFTQSSQLILHHRIHTGEKPYKCEECGKAFIRSSQ 237

Query: 569 LRLHMLRHSDRKDFLCSTCGKQFKRKDKLREHMQRMHNPER--EAKKADRISRSKTFKPR 626
           L  H   H+  K + C  CGK F +  +L  H QR+H  E+  E K+  ++    +    
Sbjct: 238 LTRHQKVHTGEKPYECKECGKAFTQNSQLTLH-QRLHTGEKLYECKECRKVFTQLSQLIL 296

Query: 627 ITSTDYDSFTFKCRLCMMGFRRRGMLVNHLSKRHPDMKIEEVPELTLPIIKPN------- 679
                     ++C+ C   F     L  H  K H   K  E  E     I+ +       
Sbjct: 297 HKRIHTGEKPYECKECGKAFICGSQLSQH-QKIHNGEKPYECKECGRAFIRGSLLMQHQR 355

Query: 680 -----RDYFCQYCDKVYKSASKRKAHILKNHPGAELPPSIRKLRPAGPGEPDPMLSTHTQ 734
                + Y C+ C K +   S+   H  + H            +P    E   M S  +Q
Sbjct: 356 IHTGEKPYKCEECGKAFIRGSQLTQH-QRIHTNE---------KPYECKECGKMFSHGSQ 405

Query: 735 LTG----TIATPPVCCPHCSKQYSSKTKMVQHIR 764
           LT          P  C  C K ++  + + +H R
Sbjct: 406 LTQHQRIHTGEKPYQCKECGKAFNRGSLLTRHQR 439



 Score = 81.6 bits (200), Expect = 3e-15
 Identities = 81/314 (25%), Positives = 118/314 (37%), Gaps = 45/314 (14%)

Query: 262 LREQEKNWPCYECNRRFISSEQLQQHLNSHDEKLDVFSRTRGRGRGRGK-----RRFGPG 316
           +   EK + C EC + F    QL QH   H  +     +  G+   RG      +R   G
Sbjct: 384 IHTNEKPYECKECGKMFSHGSQLTQHQRIHTGEKPYQCKECGKAFNRGSLLTRHQRIHTG 443

Query: 317 RRPGRPPKFIRLEITSENGEKSDDGTQ----DLLHFPTKE-QFDEAEPATLNGLDQPEQT 371
            +P             E G+    G++    + +H   K  +  E   + + G    +  
Sbjct: 444 EKPYE---------CKECGKTFSRGSELTQHERIHTGEKPYECKECGKSFIRGSQLTQHQ 494

Query: 372 TIPIPQLPQE--------TQSS-LEHEPETHTLHLQPQHEES---------VVPTQSTLT 413
            I   + P E        TQSS L      HT        E          ++  Q   T
Sbjct: 495 RIHTGEKPYECKECRMAFTQSSHLSQHQRLHTGEKPYVCNECGKAFARGLLLIQHQRIHT 554

Query: 414 ADDMRRAKR-----IRNAAL-QHLFIRKSFRPFKCLQCGKAFREKDKLDQHLRFHGREGN 467
            +   + K      IR + L QH  I    +P++C +CGKAF    +L  H R H   G 
Sbjct: 555 GEKPYQCKECGKAFIRGSQLTQHQRIHTGEKPYECKECGKAFSHGSQLTLHQRIH--TGE 612

Query: 468 CPLTCDLCNKGFISSTSLESHMKLHSDQKTYSCIFCPESFDRLDLLKDHVAIHINDGYFT 527
            P  C  C K F  S+ L  H ++H+ +K Y C  C ++F R   L  H  IHI++  F 
Sbjct: 613 KPYECRECRKAFTQSSHLSRHQRIHTGEKPYQCKECGKAFTRGSQLTQHQRIHISEKSFE 672

Query: 528 CPTCKKRFPDFIQV 541
              C   F    QV
Sbjct: 673 YKECGIDFSHGSQV 686



 Score = 42.4 bits (98), Expect = 0.002
 Identities = 52/226 (23%), Positives = 87/226 (38%), Gaps = 37/226 (16%)

Query: 253 DISEEERKVLREQEKNWPCYECNRRFISSEQLQQHLNSH--------DEKLDVFSRTRGR 304
           ++++ ER  +   EK + C EC + FI   QL QH   H         E    F+++   
Sbjct: 461 ELTQHER--IHTGEKPYECKECGKSFIRGSQLTQHQRIHTGEKPYECKECRMAFTQSSHL 518

Query: 305 GRGRGKRRFGPGRRPGRPPKFIRLEITSENGEKSDDGTQDLLH--FPTKE---QFDEAEP 359
            +    +R   G +P          + +E G+    G   + H    T E   Q  E   
Sbjct: 519 SQ---HQRLHTGEKP---------YVCNECGKAFARGLLLIQHQRIHTGEKPYQCKECGK 566

Query: 360 ATLNGLDQPEQTTIPIPQLPQETQ---SSLEHEPETHTLHLQPQHEESVVPTQSTLTADD 416
           A + G    +   I   + P E +    +  H  +  TLH      + +   +      +
Sbjct: 567 AFIRGSQLTQHQRIHTGEKPYECKECGKAFSHGSQL-TLH------QRIHTGEKPYECRE 619

Query: 417 MRRAKRIRNAALQHLFIRKSFRPFKCLQCGKAFREKDKLDQHLRFH 462
            R+A    +   +H  I    +P++C +CGKAF    +L QH R H
Sbjct: 620 CRKAFTQSSHLSRHQRIHTGEKPYQCKECGKAFTRGSQLTQHQRIH 665


>gi|210031219 zinc finger protein 845 [Homo sapiens]
          Length = 970

 Score =  144 bits (363), Expect = 4e-34
 Identities = 91/285 (31%), Positives = 125/285 (43%), Gaps = 27/285 (9%)

Query: 424 RNAALQ-HLFIRKSFRPFKCLQCGKAFREKDKLDQHLRFHGREGNCPLTCDLCNKGFISS 482
           RN+AL  H  I    +P+KC +CGKAF +K  L  HLR H   G  P  C+ C+K F   
Sbjct: 702 RNSALIIHKAIHTGEKPYKCNECGKAFSQKSSLTCHLRLH--TGEKPYKCEECDKVFSRK 759

Query: 483 TSLESHMKLHSDQKTYSCIFCPESFDRLDLLKDHVAIHINDGYFTCPTCKKRFPDFIQVK 542
           +SLE H ++H+ +K Y C  C ++F R   L  H  IH  +  + C  C K F     + 
Sbjct: 760 SSLEKHRRIHTGEKPYKCKVCDKAFGRDSHLAQHTRIHTGEKPYKCNECGKNFRHNSALV 819

Query: 543 KHVRSFHSEKIYQCTECDKAFCRPDKLRLHMLRHSDRKDFLCSTCGKQFKRKDKLREHMQ 602
            H      EK Y+C EC K F     L +H   H+  K + CS CGK F RK  L  H  
Sbjct: 820 IHKAIHSGEKPYKCNECGKTFRHNSALEIHKAIHTGEKPYKCSECGKVFNRKANLSRH-H 878

Query: 603 RMHNPEREAK--KADRISRSKTFKPRITSTDYDSFTFKCRLCMMGFRRRGMLVNHLSKRH 660
           R+H  E+  K  K  ++   +               +KC  C   FR   +LV H +   
Sbjct: 879 RLHTGEKPYKCNKCGKVFNQQAHLACHHRIHTGEKPYKCNECGKTFRHNSVLVIHKT--- 935

Query: 661 PDMKIEEVPELTLPIIKPNRDYFCQYCDKVYKSASKRKAHILKNH 705
                         I    + Y C  C KV+     RKA + ++H
Sbjct: 936 --------------IHTGEKPYKCNECGKVF----NRKAKLARHH 962



 Score =  134 bits (338), Expect = 3e-31
 Identities = 100/342 (29%), Positives = 139/342 (40%), Gaps = 36/342 (10%)

Query: 429 QHLFIRKSFRPFKCLQCGKAFREKDKLDQHLRFHGREGNCPLTCDLCNKGFISSTSLESH 488
           +H  I    +P+KC +C + F  K  L +H R H   G  P  C+ C K F   +SL  H
Sbjct: 372 RHRKIHTGEKPYKCNECSRTFSRKSSLTRHRRLH--TGEKPYKCNDCGKTFSQMSSLVYH 429

Query: 489 MKLHSDQKTYSCIFCPESFDRLDLLKDHVAIHINDGYFTCPTCKKRFPDFIQVKKHVRSF 548
            +LH+ +K Y C  C E+F     L+ H  IH  +  + C  C K F     +  H R  
Sbjct: 430 RRLHTGEKPYKCEECDEAFSFKSNLERHRRIHTGEKPYKCNDCGKTFSQTSSLVYHRRLH 489

Query: 549 HSEKIYQCTECDKAFCRPDKLRLHMLRHSDRKDFLCSTCGKQFKRKDKLREHMQRMHNPE 608
             EK Y+C ECD+AF     L  H + H+  K + C+ CGK F RK  L  H  R+H  E
Sbjct: 490 TGEKPYKCEECDEAFSFKSNLERHRIIHTGEKLYKCNECGKTFSRKSSLTRHC-RLHTGE 548

Query: 609 R-----EAKKADRISRSKTFKPRITSTDYDSFTFKCRLCMMGFRRRGMLVNHLSKRHPDM 663
           +     E  KA R   +  +   I         +KC  C   F     + NH        
Sbjct: 549 KPYQCNECGKAFRGQSALIYHQAIHGI---GKLYKCNDCHQVFSNATTIANHWR------ 599

Query: 664 KIEEVPELTLPIIKPNRDYFCQYCDKVYKSASKRKAHILKNHPGAELPPSIRKLRPAGPG 723
                      I    R Y C  C K ++  S    H  + H G E P    +   A   
Sbjct: 600 -----------IHNEERSYKCNRCGKFFRHRSYLAVH-WRTHSG-EKPYKCEECDEAFSF 646

Query: 724 EPDPMLSTHTQL-TGTIATPPVCCPHCSKQYSSKTKMVQHIR 764
           + +  L  H ++ TG     P  C  C K +S K+ +  H R
Sbjct: 647 KSN--LQRHRRIHTG---EKPYRCNECGKTFSRKSYLTCHRR 683



 Score =  129 bits (323), Expect = 2e-29
 Identities = 107/370 (28%), Positives = 153/370 (41%), Gaps = 40/370 (10%)

Query: 422 RIRNAALQHLFIRKSFRPFKCLQCGKAFREKDKLDQHLRFHGREGNCPLTCDLCNKGFIS 481
           R R+    H       +P+KC +C +AF  K  L +H R H   G  P  C+ C K F  
Sbjct: 617 RHRSYLAVHWRTHSGEKPYKCEECDEAFSFKSNLQRHRRIH--TGEKPYRCNECGKTFSR 674

Query: 482 STSLESHMKLHSDQKTYSCIFCPESFDRLDLLKDHVAIHINDGYFTCPTCKKRFPDFIQV 541
            + L  H +LH+ +K Y C  C ++F R   L  H AIH  +  + C  C K F     +
Sbjct: 675 KSYLTCHRRLHTGEKPYKCNECGKTFGRNSALIIHKAIHTGEKPYKCNECGKAFSQKSSL 734

Query: 542 KKHVRSFHSEKIYQCTECDKAFCRPDKLRLHMLRHSDRKDFLCSTCGKQFKRKDKLREHM 601
             H+R    EK Y+C ECDK F R   L  H   H+  K + C  C K F R   L +H 
Sbjct: 735 TCHLRLHTGEKPYKCEECDKVFSRKSSLEKHRRIHTGEKPYKCKVCDKAFGRDSHLAQH- 793

Query: 602 QRMHNPER-----EAKKADRISRSKTFKPRITSTDYDSFTFKCRLCMMGFRRRGMLVNHL 656
            R+H  E+     E  K  R + +      I S +     +KC  C   FR    L  H 
Sbjct: 794 TRIHTGEKPYKCNECGKNFRHNSALVIHKAIHSGEK---PYKCNECGKTFRHNSALEIHK 850

Query: 657 S-----KRHPDMKIEEVPELTLPIIKPNR------DYFCQYCDKVYKSASKRKAHILKNH 705
           +     K +   +  +V      + + +R       Y C  C KV+     ++AH+  +H
Sbjct: 851 AIHTGEKPYKCSECGKVFNRKANLSRHHRLHTGEKPYKCNKCGKVF----NQQAHLACHH 906

Query: 706 --PGAELPPSIRKLRPAGPG-EPDPMLSTHTQL-TGTIATPPVCCPHCSKQYSSKTKMVQ 761
                E P    K    G     + +L  H  + TG     P  C  C K ++ K K+ +
Sbjct: 907 RIHTGEKP---YKCNECGKTFRHNSVLVIHKTIHTG---EKPYKCNECGKVFNRKAKLAR 960

Query: 762 HIR----KKH 767
           H R    KKH
Sbjct: 961 HHRIHTGKKH 970



 Score =  127 bits (319), Expect = 5e-29
 Identities = 103/380 (27%), Positives = 155/380 (40%), Gaps = 34/380 (8%)

Query: 402 EESVVPTQSTLTADDMRRAKRIRNAALQHLFIRKSFRPFKCLQCGKAFREKDKLDQHLRF 461
           ++ V   + +   ++  +A    +   +H  I    + +KC  CGK F +K  L  H R 
Sbjct: 205 KQEVHMREKSFQCNESGKAFNYSSVLRKHQIIHLGAKQYKCDVCGKVFNQKRYLACHRRC 264

Query: 462 HGREGNCPLTCDLCNKGFISSTSLESHMKLHSDQKTYSCIFCPESFDRLDLLKDHVAIHI 521
           H   G  P  C+ C K F    +L  H +LH+ +K Y C  C ++F R   L  H AIH 
Sbjct: 265 H--TGKKPYKCNDCGKTFSQELTLTCHHRLHTGEKHYKCSECGKTFSRNSALVIHKAIHT 322

Query: 522 NDGYFTCPTCKKRFPDFIQVKKHVRSFHSEKIYQCTECDKAFCRPDKLRLHMLRHSDRKD 581
            +  + C  C K F     +  H R    EK Y+C ECDKAF     L  H   H+  K 
Sbjct: 323 GEKSYKCNECGKTFSQTSYLVYHRRLHTGEKPYKCEECDKAFSFKSNLERHRKIHTGEKP 382

Query: 582 FLCSTCGKQFKRKDKLREHMQRMHNPEREAKKADRISRSKTFKPRITSTDY------DSF 635
           + C+ C + F RK  L  H +R+H  E+  K  D     KTF  +++S  Y         
Sbjct: 383 YKCNECSRTFSRKSSLTRH-RRLHTGEKPYKCND---CGKTFS-QMSSLVYHRRLHTGEK 437

Query: 636 TFKCRLCMMGFRRRGMLVNHL-----SKRHPDMKIEEVPELTLPIIKPNR------DYFC 684
            +KC  C   F  +  L  H       K +      +    T  ++   R       Y C
Sbjct: 438 PYKCEECDEAFSFKSNLERHRRIHTGEKPYKCNDCGKTFSQTSSLVYHRRLHTGEKPYKC 497

Query: 685 QYCDKVYKSASKRKAHILKNHPGAELPPSIRKLRPAGPG-EPDPMLSTHTQL-TGTIATP 742
           + CD+ +   S  + H +  H G +L     K    G        L+ H +L TG     
Sbjct: 498 EECDEAFSFKSNLERHRI-IHTGEKL----YKCNECGKTFSRKSSLTRHCRLHTG---EK 549

Query: 743 PVCCPHCSKQYSSKTKMVQH 762
           P  C  C K +  ++ ++ H
Sbjct: 550 PYQCNECGKAFRGQSALIYH 569



 Score =  120 bits (301), Expect = 7e-27
 Identities = 88/340 (25%), Positives = 143/340 (42%), Gaps = 54/340 (15%)

Query: 424 RNAALQHLFIRKSFRPFKCLQCGKAFREKDKLDQHLRFHGREGNCPLTCDLCNKGFISST 483
           +++  +H  +    +P++C +CGKAFR +  L  H   HG        C+ C++ F ++T
Sbjct: 535 KSSLTRHCRLHTGEKPYQCNECGKAFRGQSALIYHQAIHGI--GKLYKCNDCHQVFSNAT 592

Query: 484 SLESHMKLHSDQKTYSCIFCPESFDRLDLLKDHVAIHINDGYFTCPTCKKRFPDFIQVKK 543
           ++ +H ++H+++++Y C  C + F     L  H   H  +  + C  C + F     +++
Sbjct: 593 TIANHWRIHNEERSYKCNRCGKFFRHRSYLAVHWRTHSGEKPYKCEECDEAFSFKSNLQR 652

Query: 544 HVRSFHSEKIYQCTECDKAFCRPDKLRLHMLRHSDRKDFLCSTCGKQFKRKDKLREHMQR 603
           H R    EK Y+C EC K F R   L  H   H+  K + C+ CGK F R   L  H + 
Sbjct: 653 HRRIHTGEKPYRCNECGKTFSRKSYLTCHRRLHTGEKPYKCNECGKTFGRNSALIIH-KA 711

Query: 604 MHNPEREAKKADRISRSKTFKPRITSTDYDSFTFKCRLCMMGFRRRGMLVNHLSKRHPDM 663
           +H  E+                           +KC  C   F ++  L  HL + H   
Sbjct: 712 IHTGEK--------------------------PYKCNECGKAFSQKSSLTCHL-RLHTGE 744

Query: 664 KIEEVPELTLPIIKPNRDYFCQYCDKVYKSASKRKAHILKNHPGAELPPSIRKLRPAGPG 723
           K                 Y C+ CDKV+   S  + H  + H G +  P   K+     G
Sbjct: 745 K----------------PYKCEECDKVFSRKSSLEKH-RRIHTGEK--PYKCKVCDKAFG 785

Query: 724 EPDPMLSTHTQL-TGTIATPPVCCPHCSKQYSSKTKMVQH 762
             D  L+ HT++ TG     P  C  C K +   + +V H
Sbjct: 786 R-DSHLAQHTRIHTG---EKPYKCNECGKNFRHNSALVIH 821



 Score =  119 bits (298), Expect = 1e-26
 Identities = 95/361 (26%), Positives = 148/361 (40%), Gaps = 26/361 (7%)

Query: 419 RAKRIRNAALQHLFIRKSFRPFKCLQCGKAFREKDKLDQHLRFHGREGNCPLTCDLCNKG 478
           +A R ++A + H  I    + +KC  C + F     +  H R H  E +    C+ C K 
Sbjct: 558 KAFRGQSALIYHQAIHGIGKLYKCNDCHQVFSNATTIANHWRIHNEERS--YKCNRCGKF 615

Query: 479 FISSTSLESHMKLHSDQKTYSCIFCPESFDRLDLLKDHVAIHINDGYFTCPTCKKRFPDF 538
           F   + L  H + HS +K Y C  C E+F     L+ H  IH  +  + C  C K F   
Sbjct: 616 FRHRSYLAVHWRTHSGEKPYKCEECDEAFSFKSNLQRHRRIHTGEKPYRCNECGKTFSRK 675

Query: 539 IQVKKHVRSFHSEKIYQCTECDKAFCRPDKLRLHMLRHSDRKDFLCSTCGKQFKRKDKLR 598
             +  H R    EK Y+C EC K F R   L +H   H+  K + C+ CGK F +K  L 
Sbjct: 676 SYLTCHRRLHTGEKPYKCNECGKTFGRNSALIIHKAIHTGEKPYKCNECGKAFSQKSSLT 735

Query: 599 EHMQRMHNPER--EAKKADRISRSKTFKPRITSTDYDSFTFKCRLCMMGFRRRGMLVNHL 656
            H+ R+H  E+  + ++ D++   K+   +          +KC++C   F R   L  H 
Sbjct: 736 CHL-RLHTGEKPYKCEECDKVFSRKSSLEKHRRIHTGEKPYKCKVCDKAFGRDSHLAQH- 793

Query: 657 SKRHPDMKIEEVPE------------LTLPIIKPNRDYFCQYCDKVYKSASKRKAHILKN 704
           ++ H   K  +  E            +   I    + Y C  C K ++  S  + H  K 
Sbjct: 794 TRIHTGEKPYKCNECGKNFRHNSALVIHKAIHSGEKPYKCNECGKTFRHNSALEIH--KA 851

Query: 705 HPGAELPPSIRKLRPAGPGEPDPMLSTHTQL-TGTIATPPVCCPHCSKQYSSKTKMVQHI 763
               E P    +       + +  LS H +L TG     P  C  C K ++ +  +  H 
Sbjct: 852 IHTGEKPYKCSECGKVFNRKAN--LSRHHRLHTG---EKPYKCNKCGKVFNQQAHLACHH 906

Query: 764 R 764
           R
Sbjct: 907 R 907



 Score = 82.8 bits (203), Expect = 2e-15
 Identities = 72/287 (25%), Positives = 111/287 (38%), Gaps = 52/287 (18%)

Query: 479 FISSTSLESHMKLHSDQKTYSCIFCPESFDRLDLLKDHVAIHINDGYFTCPTCKKRFPDF 538
           F++S+ L    ++H  +K++ C    ++F+   +L+ H  IH+    + C  C K F   
Sbjct: 196 FLNSSLLTQKQEVHMREKSFQCNESGKAFNYSSVLRKHQIIHLGAKQYKCDVCGKVFNQK 255

Query: 539 IQVKKHVRSFHSEKIYQCTECDKAFCRPDKLRLHMLRHSDRKDFLCSTCGKQFKRKDKLR 598
             +  H R    +K Y+C +C K F +   L  H   H+  K + CS CGK F R   L 
Sbjct: 256 RYLACHRRCHTGKKPYKCNDCGKTFSQELTLTCHHRLHTGEKHYKCSECGKTFSRNSALV 315

Query: 599 EHMQRMHNPEREAKKADRISRSKTFKPRITSTDYDSFTFKCRLCMMGFRRRGMLVNHLSK 658
            H + +H  E+                          ++KC  C   F +   LV H  +
Sbjct: 316 IH-KAIHTGEK--------------------------SYKCNECGKTFSQTSYLVYH-RR 347

Query: 659 RHPDMKIEEVPELTLPIIKPNRDYFCQYCDKVYKSASKRKAHILKNHPGAELPPSIRKLR 718
            H   K                 Y C+ CDK +   S  + H  K H G E P    +  
Sbjct: 348 LHTGEK----------------PYKCEECDKAFSFKSNLERH-RKIHTG-EKPYKCNECS 389

Query: 719 PAGPGEPDPMLSTHTQL-TGTIATPPVCCPHCSKQYSSKTKMVQHIR 764
                +    L+ H +L TG     P  C  C K +S  + +V H R
Sbjct: 390 RTFSRKSS--LTRHRRLHTG---EKPYKCNDCGKTFSQMSSLVYHRR 431


>gi|38570117 zinc finger protein 569 [Homo sapiens]
          Length = 686

 Score =  144 bits (362), Expect = 6e-34
 Identities = 106/355 (29%), Positives = 156/355 (43%), Gaps = 32/355 (9%)

Query: 428 LQHLFIRKSFRPFKCLQCGKAFREKDKLDQHLRFHGREGNCPLTCDLCNKGFISSTSLES 487
           ++HL I    +P++C  C KAF  K+KL +H + H RE +    C+ C K FI  ++L  
Sbjct: 202 IRHLRIHTGEKPYECSNCRKAFSHKEKLIKHYKIHSREQS--YKCNECGKAFIKMSNLIR 259

Query: 488 HMKLHSDQKTYSCIFCPESFDRLDLLKDHVAIHINDGYFTCPTCKKRFPDFIQVKKHVRS 547
           H ++H+ +K Y+C  C +SF +   L DH  IH  +  + C  C K F     +  H + 
Sbjct: 260 HQRIHTGEKPYACKECEKSFSQKSNLIDHEKIHTGEKPYECNECGKAFSQKQSLIAHQKV 319

Query: 548 FHSEKIYQCTECDKAFCRPDKLRLHMLRHSDRKDFLCSTCGKQFKRKDKLREHMQRMHNP 607
              EK Y C EC KAF R   L LHM  H+  K + C  CGK F +   L  H+ R+H  
Sbjct: 320 HTGEKPYACNECGKAFPRIASLALHMRSHTGEKPYKCDKCGKAFSQFSMLIIHV-RIHTG 378

Query: 608 ER-----EAKKADRISRSKTFKPRITSTDYDSFTFKCRLCMMGFRRRGMLVNHLSKRHPD 662
           E+     E  KA   S + T   R  + +     ++C+ C   F  +   + H  K H  
Sbjct: 379 EKPYECNECGKAFSQSSALTVHMRSHTGEK---PYECKECRKAFSHKKNFITH-QKIHTR 434

Query: 663 MKIEEVPELTLPIIKPN------------RDYFCQYCDKVYKSASKRKAHILKNHPGAEL 710
            K  E  E     I+ +            + Y C+ C K +   S   AH  K H G E 
Sbjct: 435 EKPYECNECGKAFIQMSNLVRHQRIHTGEKPYICKECGKAFSQKSNLIAH-EKIHSG-EK 492

Query: 711 PPSIRKLRPAGPGEPDPMLSTHTQL-TGTIATPPVCCPHCSKQYSSKTKMVQHIR 764
           P    +   A   + +    TH ++ TG     P  C  C K +S    +  H+R
Sbjct: 493 PYECNECGKAFSQKQN--FITHQKVHTG---EKPYDCNECGKAFSQIASLTLHLR 542



 Score =  140 bits (354), Expect = 5e-33
 Identities = 96/351 (27%), Positives = 147/351 (41%), Gaps = 24/351 (6%)

Query: 428 LQHLFIRKSFRPFKCLQCGKAFREKDKLDQHLRFHGREGNCPLTCDLCNKGFISSTSLES 487
           ++H  I    +P+ C +C K+F +K  L  H + H   G  P  C+ C K F    SL +
Sbjct: 258 IRHQRIHTGEKPYACKECEKSFSQKSNLIDHEKIH--TGEKPYECNECGKAFSQKQSLIA 315

Query: 488 HMKLHSDQKTYSCIFCPESFDRLDLLKDHVAIHINDGYFTCPTCKKRFPDFIQVKKHVRS 547
           H K+H+ +K Y+C  C ++F R+  L  H+  H  +  + C  C K F  F  +  HVR 
Sbjct: 316 HQKVHTGEKPYACNECGKAFPRIASLALHMRSHTGEKPYKCDKCGKAFSQFSMLIIHVRI 375

Query: 548 FHSEKIYQCTECDKAFCRPDKLRLHMLRHSDRKDFLCSTCGKQFKRKDKLREHMQRMHNP 607
              EK Y+C EC KAF +   L +HM  H+  K + C  C K F  K     H Q++H  
Sbjct: 376 HTGEKPYECNECGKAFSQSSALTVHMRSHTGEKPYECKECRKAFSHKKNFITH-QKIHTR 434

Query: 608 ER--EAKKADRISRSKTFKPRITSTDYDSFTFKCRLCMMGFRRRGMLVNHLSKRHPDMKI 665
           E+  E  +  +     +   R          + C+ C   F ++  L+ H  K H   K 
Sbjct: 435 EKPYECNECGKAFIQMSNLVRHQRIHTGEKPYICKECGKAFSQKSNLIAH-EKIHSGEKP 493

Query: 666 EEVPELTLPIIKP------------NRDYFCQYCDKVYKSASKRKAHILKNHPGAELPPS 713
            E  E      +              + Y C  C K +   +    H L++H G E P  
Sbjct: 494 YECNECGKAFSQKQNFITHQKVHTGEKPYDCNECGKAFSQIASLTLH-LRSHTG-EKPYE 551

Query: 714 IRKLRPAGPGEPDPMLSTHTQLTGTIATPPVCCPHCSKQYSSKTKMVQHIR 764
             K   A       +L+ H  +       P  C  C K +S +T ++ H+R
Sbjct: 552 CDKCGKA--FSQCSLLNLH--MRSHTGEKPYVCNECGKAFSQRTSLIVHMR 598



 Score =  133 bits (335), Expect = 7e-31
 Identities = 98/375 (26%), Positives = 149/375 (39%), Gaps = 42/375 (11%)

Query: 428 LQHLFIRKSFRPFKCLQCGKAFREKDKLDQHLRFHGREGNCPLTCDLCNKGFISSTSLES 487
           + H  I    +P++C +CGKAF +K  L  H + H   G  P  C+ C K F    SL  
Sbjct: 286 IDHEKIHTGEKPYECNECGKAFSQKQSLIAHQKVH--TGEKPYACNECGKAFPRIASLAL 343

Query: 488 HMKLHSDQKTYSCIFCPESFDRLDLLKDHVAIHINDGYFTCPTCKKRFPDFIQVKKHVRS 547
           HM+ H+ +K Y C  C ++F +  +L  HV IH  +  + C  C K F     +  H+RS
Sbjct: 344 HMRSHTGEKPYKCDKCGKAFSQFSMLIIHVRIHTGEKPYECNECGKAFSQSSALTVHMRS 403

Query: 548 FHSEKIYQCTECDKAFCRPDKLRLHMLRHSDRKDFLCSTCGKQFKRKDKLREHMQRMHNP 607
              EK Y+C EC KAF        H   H+  K + C+ CGK F +   L  H QR+H  
Sbjct: 404 HTGEKPYECKECRKAFSHKKNFITHQKIHTREKPYECNECGKAFIQMSNLVRH-QRIHTG 462

Query: 608 ERE--AKKADRISRSKTFKPRITSTDYDSFTFKCRLCMMGFRRRGMLVNHLSKRHPDMK- 664
           E+    K+  +    K+              ++C  C   F ++   + H  K H   K 
Sbjct: 463 EKPYICKECGKAFSQKSNLIAHEKIHSGEKPYECNECGKAFSQKQNFITH-QKVHTGEKP 521

Query: 665 ---------IEEVPELTLPIIKPN--RDYFCQYCDKVYKSASKRKAHILKNHPGAE---- 709
                      ++  LTL +      + Y C  C K +   S    H +++H G +    
Sbjct: 522 YDCNECGKAFSQIASLTLHLRSHTGEKPYECDKCGKAFSQCSLLNLH-MRSHTGEKPYVC 580

Query: 710 ------------LPPSIRKLRPAGPGEPDPMLSTHTQ-------LTGTIATPPVCCPHCS 750
                       L   +R      P E +      +Q       + G     P  C  C 
Sbjct: 581 NECGKAFSQRTSLIVHMRGHTGEKPYECNKCGKAFSQSSSLTIHIRGHTGEKPFDCSKCG 640

Query: 751 KQYSSKTKMVQHIRK 765
           K +S  + +  H+RK
Sbjct: 641 KAFSQISSLTLHMRK 655



 Score =  133 bits (334), Expect = 1e-30
 Identities = 83/292 (28%), Positives = 131/292 (44%), Gaps = 28/292 (9%)

Query: 416 DMRRAKRIRNAALQHLFIRKSFRPFKCLQCGKAFREKDKLDQHLRFHGREGNCPLTCDLC 475
           + R+A   +   + H  I    +P++C +CGKAF +   L +H R H   G  P  C  C
Sbjct: 414 ECRKAFSHKKNFITHQKIHTREKPYECNECGKAFIQMSNLVRHQRIH--TGEKPYICKEC 471

Query: 476 NKGFISSTSLESHMKLHSDQKTYSCIFCPESFDRLDLLKDHVAIHINDGYFTCPTCKKRF 535
            K F   ++L +H K+HS +K Y C  C ++F +      H  +H  +  + C  C K F
Sbjct: 472 GKAFSQKSNLIAHEKIHSGEKPYECNECGKAFSQKQNFITHQKVHTGEKPYDCNECGKAF 531

Query: 536 PDFIQVKKHVRSFHSEKIYQCTECDKAFCRPDKLRLHMLRHSDRKDFLCSTCGKQFKRKD 595
                +  H+RS   EK Y+C +C KAF +   L LHM  H+  K ++C+ CGK F ++ 
Sbjct: 532 SQIASLTLHLRSHTGEKPYECDKCGKAFSQCSLLNLHMRSHTGEKPYVCNECGKAFSQRT 591

Query: 596 KLREHMQRMHNPER--EAKKADR-ISRSKTFKPRITSTDYDSFTFKCRLCMMGFRRRGML 652
            L  HM R H  E+  E  K  +  S+S +    I     +   F C  C   F +   L
Sbjct: 592 SLIVHM-RGHTGEKPYECNKCGKAFSQSSSLTIHIRGHTGEK-PFDCSKCGKAFSQISSL 649

Query: 653 VNHLSKRHPDMKIEEVPELTLPIIKPNRDYFCQYCDKVYKSASKRKAHILKN 704
             H+ K   +                 + Y C  C K +     +K+H++++
Sbjct: 650 TLHMRKHTGE-----------------KPYHCIECGKAF----SQKSHLVRH 680



 Score =  131 bits (330), Expect = 3e-30
 Identities = 91/326 (27%), Positives = 132/326 (40%), Gaps = 52/326 (15%)

Query: 439 PFKCLQCGKAFREKDKLDQHLRFHGREGNCPLTCDLCNKGFISSTSLESHMKLHSDQKTY 498
           PFKC  CGK F +   L +HLR H   G  P  C  C K F     L  H K+HS +++Y
Sbjct: 185 PFKCNHCGKGFNQTLDLIRHLRIH--TGEKPYECSNCRKAFSHKEKLIKHYKIHSREQSY 242

Query: 499 SCIFCPESFDRLDLLKDHVAIHINDGYFTCPTCKKRFPDFIQVKKHVRSFHSEKIYQCTE 558
            C  C ++F ++  L  H  IH  +  + C  C+K F     +  H +    EK Y+C E
Sbjct: 243 KCNECGKAFIKMSNLIRHQRIHTGEKPYACKECEKSFSQKSNLIDHEKIHTGEKPYECNE 302

Query: 559 CDKAFCRPDKLRLHMLRHSDRKDFLCSTCGKQFKRKDKLREHMQRMHNPEREAKKADRIS 618
           C KAF +   L  H   H+  K + C+ CGK F R   L  HM R H  E+         
Sbjct: 303 CGKAFSQKQSLIAHQKVHTGEKPYACNECGKAFPRIASLALHM-RSHTGEK--------- 352

Query: 619 RSKTFKPRITSTDYDSFTFKCRLCMMGFRRRGMLVNHLSKRHPDMKIEEVPELTLPIIKP 678
                             +KC  C   F +  ML+ H+                  I   
Sbjct: 353 -----------------PYKCDKCGKAFSQFSMLIIHVR-----------------IHTG 378

Query: 679 NRDYFCQYCDKVYKSASKRKAHILKNHPGAELPPSIRKLRPAGPGEPDPMLSTHTQLTGT 738
            + Y C  C K +  +S    H +++H G E P   ++ R A   + +    TH ++   
Sbjct: 379 EKPYECNECGKAFSQSSALTVH-MRSHTG-EKPYECKECRKAFSHKKN--FITHQKI--H 432

Query: 739 IATPPVCCPHCSKQYSSKTKMVQHIR 764
               P  C  C K +   + +V+H R
Sbjct: 433 TREKPYECNECGKAFIQMSNLVRHQR 458



 Score =  121 bits (304), Expect = 3e-27
 Identities = 62/178 (34%), Positives = 89/178 (50%), Gaps = 3/178 (1%)

Query: 428 LQHLFIRKSFRPFKCLQCGKAFREKDKLDQHLRFHGREGNCPLTCDLCNKGFISSTSLES 487
           + H  +    +P+ C +CGKAF +   L  HLR H   G  P  CD C K F   + L  
Sbjct: 510 ITHQKVHTGEKPYDCNECGKAFSQIASLTLHLRSH--TGEKPYECDKCGKAFSQCSLLNL 567

Query: 488 HMKLHSDQKTYSCIFCPESFDRLDLLKDHVAIHINDGYFTCPTCKKRFPDFIQVKKHVRS 547
           HM+ H+ +K Y C  C ++F +   L  H+  H  +  + C  C K F     +  H+R 
Sbjct: 568 HMRSHTGEKPYVCNECGKAFSQRTSLIVHMRGHTGEKPYECNKCGKAFSQSSSLTIHIRG 627

Query: 548 FHSEKIYQCTECDKAFCRPDKLRLHMLRHSDRKDFLCSTCGKQFKRKDKLREHMQRMH 605
              EK + C++C KAF +   L LHM +H+  K + C  CGK F +K  L  H QR+H
Sbjct: 628 HTGEKPFDCSKCGKAFSQISSLTLHMRKHTGEKPYHCIECGKAFSQKSHLVRH-QRIH 684



 Score = 45.8 bits (107), Expect = 2e-04
 Identities = 21/56 (37%), Positives = 29/56 (51%), Gaps = 2/56 (3%)

Query: 438 RPFKCLQCGKAFREKDKLDQHLRFHGREGNCPLTCDLCNKGFISSTSLESHMKLHS 493
           +PF C +CGKAF +   L  H+R H   G  P  C  C K F   + L  H ++H+
Sbjct: 632 KPFDCSKCGKAFSQISSLTLHMRKH--TGEKPYHCIECGKAFSQKSHLVRHQRIHT 685


>gi|89001105 zinc finger protein 571 [Homo sapiens]
          Length = 609

 Score =  143 bits (360), Expect = 9e-34
 Identities = 150/624 (24%), Positives = 243/624 (38%), Gaps = 75/624 (12%)

Query: 175 DRKERDLHEDLWFE-------LSDETLCNWMMFVRPAQNHLEQNL----VAYQYGHHVYY 223
           D  +RDL+ D+  E       L  E+ C         + +  ++L    +  +  HH+ Y
Sbjct: 24  DPAQRDLYRDVMLENYSNLISLDLESSCVTKKLSPEKEIYEMESLQWENMGKRINHHLQY 83

Query: 224 TTI-KNVEPKQELKVWYAASYAEFVNQKI---------HDISEEERKVLREQEKNWPCYE 273
             +  N+E K  L+   A+    ++  KI         H  S    +++  +EK + C E
Sbjct: 84  NGLGDNMECKGNLEGQEASQEGLYMCVKITCEEKATESHSTSSTFHRIIPTKEKLYKCKE 143

Query: 274 CNRRFISSEQLQQHLNSHD-EKLDVFSRTRGRGRGRGK----RRFGPGRRPGRPPKFIRL 328
           C + F     L QH  +H+ EK     + R     +      +R   G +P     +  +
Sbjct: 144 CRQGFSYLSCLIQHEENHNIEKCSEVKKHRNTFSKKPSYIQHQRIQTGEKP-----YECM 198

Query: 329 EITSENGEKSDDGTQDLLHFPTKE-QFDEAEPATLNGLDQPEQTTIPIPQLPQETQ--SS 385
           E     G  SD      +H   K  Q +    A + G    E   +   + P E +    
Sbjct: 199 ECGKAFGRTSDLIQHQKIHTNEKPYQCNACGKAFIRGSQLTEHQRVHTGEKPYECKKCGK 258

Query: 386 LEHEPETHTLHLQPQHEESVVPTQSTLTADDMRRAKRIRNAALQHLFIRKSFRPFKCLQC 445
                  +TLH      + +   +      D  +A  + +    H  I    +P++C +C
Sbjct: 259 AFSYCSQYTLH------QRIHSGEKPYECKDCGKAFILGSQLTYHQRIHSGEKPYECKEC 312

Query: 446 GKAFREKDKLDQHLRFHGREGNCPLTCDLCNKGFISSTSLESHMKLHSDQKTYSCIFCPE 505
           GKAF     L  H R H   G  P  C  C K F+ ++ L  H ++H+ +K Y C  C +
Sbjct: 313 GKAFILGSHLTYHQRVH--TGEKPYICKECGKAFLCASQLNEHQRIHTGEKPYECKECGK 370

Query: 506 SFDRLDLLKDHVAIHINDGYFTCPTCKKRFPDFIQVKKHVRSFHSEKIYQCTECDKAFCR 565
           +F R   L  H+ +H  +  + C  C K F     + +H R    EK Y+C EC KAF  
Sbjct: 371 TFFRGSQLTYHLRVHSGERPYKCKECGKAFISNSNLIQHQRIHTGEKPYKCKECGKAFIC 430

Query: 566 PDKLRLHMLRHSDRKDFLCSTCGKQFKRKDKLREHMQRMHNPE----REAKKADRISRSK 621
             +L  H   H+  K F C  CGK F R   L +H +++H  +    +E  K    +   
Sbjct: 431 GKQLSEHQRIHTGEKPFECKECGKAFIRVAYLTQH-EKIHGEKHYECKECGKTFVRATQL 489

Query: 622 TFKPRITSTDYDSFTFKCRLCMMGFRRRGMLVNHLSKRHPDMKIEEVPELTLPIIKPNRD 681
           T+  RI + +     +KC+ C   F     L  H                   I +  + 
Sbjct: 490 TYHQRIHTGEK---PYKCKECDKAFIYGSQLSEHQR-----------------IHRGEKP 529

Query: 682 YFCQYCDKVYKSASKRKAHILKNHPGAELPPSIRKLRPAGPGEPDPMLSTHTQL-TGTIA 740
           Y C+ C K +   S    H L+ H G E P   ++   A     +  L+ H ++ TG   
Sbjct: 530 YECKQCGKAFIRGSHLTEH-LRTHTG-EKPYECKECGRAFSRGSE--LTLHQRIHTG--- 582

Query: 741 TPPVCCPHCSKQYSSKTKMVQHIR 764
             P  C  C K +   +++ QH R
Sbjct: 583 EKPYTCVQCGKDFRCPSQLTQHTR 606



 Score =  124 bits (310), Expect = 6e-28
 Identities = 62/178 (34%), Positives = 92/178 (51%), Gaps = 4/178 (2%)

Query: 429 QHLFIRKSFRPFKCLQCGKAFREKDKLDQHLRFHGREGNCPLTCDLCNKGFISSTSLESH 488
           +H  I    +PF+C +CGKAF     L QH + HG +      C  C K F+ +T L  H
Sbjct: 436 EHQRIHTGEKPFECKECGKAFIRVAYLTQHEKIHGEKH---YECKECGKTFVRATQLTYH 492

Query: 489 MKLHSDQKTYSCIFCPESFDRLDLLKDHVAIHINDGYFTCPTCKKRFPDFIQVKKHVRSF 548
            ++H+ +K Y C  C ++F     L +H  IH  +  + C  C K F     + +H+R+ 
Sbjct: 493 QRIHTGEKPYKCKECDKAFIYGSQLSEHQRIHRGEKPYECKQCGKAFIRGSHLTEHLRTH 552

Query: 549 HSEKIYQCTECDKAFCRPDKLRLHMLRHSDRKDFLCSTCGKQFKRKDKLREHMQRMHN 606
             EK Y+C EC +AF R  +L LH   H+  K + C  CGK F+   +L +H  R+HN
Sbjct: 553 TGEKPYECKECGRAFSRGSELTLHQRIHTGEKPYTCVQCGKDFRCPSQLTQH-TRLHN 609



 Score =  103 bits (256), Expect = 1e-21
 Identities = 103/371 (27%), Positives = 147/371 (39%), Gaps = 41/371 (11%)

Query: 430 HLFIRKSFRPFKCLQCGKAFREKDKLDQHLRFHGREGNCPLTCDLCNKG---FISSTSLE 486
           H  I    + +KC +C + F     L QH   H  E      C    K    F    S  
Sbjct: 129 HRIIPTKEKLYKCKECRQGFSYLSCLIQHEENHNIE-----KCSEVKKHRNTFSKKPSYI 183

Query: 487 SHMKLHSDQKTYSCIFCPESFDRLDLLKDHVAIHINDGYFTCPTCKKRFPDFIQVKKHVR 546
            H ++ + +K Y C+ C ++F R   L  H  IH N+  + C  C K F    Q+ +H R
Sbjct: 184 QHQRIQTGEKPYECMECGKAFGRTSDLIQHQKIHTNEKPYQCNACGKAFIRGSQLTEHQR 243

Query: 547 SFHSEKIYQCTECDKAFCRPDKLRLHMLRHSDRKDFLCSTCGKQFKRKDKLREHMQRMHN 606
               EK Y+C +C KAF    +  LH   HS  K + C  CGK F    +L  H QR+H+
Sbjct: 244 VHTGEKPYECKKCGKAFSYCSQYTLHQRIHSGEKPYECKDCGKAFILGSQLTYH-QRIHS 302

Query: 607 PE-----REAKKADRISRSKTFKPRITSTDYDSFTFKCRLCMMGFRRRGMLVNHLSKRHP 661
            E     +E  KA  +    T+  R+ + +     + C+ C   F     L  H  + H 
Sbjct: 303 GEKPYECKECGKAFILGSHLTYHQRVHTGEK---PYICKECGKAFLCASQLNEH-QRIHT 358

Query: 662 DMKIEEVPE----------LT--LPIIKPNRDYFCQYCDKVYKSASKRKAHILKNHPGAE 709
             K  E  E          LT  L +    R Y C+ C K + S S    H  + H G E
Sbjct: 359 GEKPYECKECGKTFFRGSQLTYHLRVHSGERPYKCKECGKAFISNSNLIQH-QRIHTG-E 416

Query: 710 LPPSIRKLRPAGPGEPDPMLSTHTQL-TGTIATPPVCCPHCSKQYSSKTKMVQHIR---K 765
            P   ++   A        LS H ++ TG     P  C  C K +     + QH +   +
Sbjct: 417 KPYKCKECGKA--FICGKQLSEHQRIHTG---EKPFECKECGKAFIRVAYLTQHEKIHGE 471

Query: 766 KHPEFAQLSNT 776
           KH E  +   T
Sbjct: 472 KHYECKECGKT 482


>gi|155722996 zinc finger protein 544 [Homo sapiens]
          Length = 715

 Score =  142 bits (359), Expect = 1e-33
 Identities = 103/344 (29%), Positives = 153/344 (44%), Gaps = 30/344 (8%)

Query: 438 RPFKCLQCGKAFREKDKLDQHLRFHGREGNCPLTCDLCNKGFISSTSLESHMKLHSDQKT 497
           +PF+C QCGK+F +   L  H R H   G  P  CDLC K F   + L +H ++H+ +K 
Sbjct: 378 KPFECTQCGKSFSQSYDLVIHQRTH--TGEKPYECDLCGKSFTQRSKLITHQRIHTGEKP 435

Query: 498 YSCIFCPESFDRLDLLKDHVAIHINDGYFTCPTCKKRFPDFIQVKKHVRSFHSEKIYQCT 557
           Y CI C +SF     L  H  IH  +  + C  C K F    ++  H R+   EK ++CT
Sbjct: 436 YQCIECRKSFRWNSNLIVHQRIHTGEKPYECTHCGKSFSQSYELVTHKRTHTGEKPFKCT 495

Query: 558 ECDKAFCRPDKLRLHMLRHSDRKDFLCSTCGKQFKRKDKLREHMQRMHNPER-----EAK 612
           +C K+F +   L +H   H+  K + C+ CGK F +  KL  H QR+H  E+     E  
Sbjct: 496 QCGKSFSQKYDLVVHQRTHTGEKPYECNLCGKSFSQSSKLITH-QRIHTGEKPYQCIECG 554

Query: 613 KADRISRSKTFKPRITSTDYDSFTFKCRLCMMGFRRRGMLVNHLSKRHPDMKIEEVPEL- 671
           K+ R + +     RI + +     + C  C   F +   LV H  + H   K  E  E  
Sbjct: 555 KSFRWNSNLVIHQRIHTGEK---PYDCTHCGKSFSQSYQLVAH-KRTHTGEKPYECNECG 610

Query: 672 -----------TLPIIKPNRDYFCQYCDKVYKSASKRKAHILKNHPGAELPPSIRKLRPA 720
                       L I    + Y C  C+K +  +S    H  + H G E P    +   A
Sbjct: 611 KAFNRSTQLIRHLQIHTGEKPYKCNQCNKAFARSSYLVMH-QRTHTG-EKPFECSQCGKA 668

Query: 721 GPGEPDPMLSTHTQLTGTIATPPVCCPHCSKQYSSKTKMVQHIR 764
             G  + +LS H   +G     P  C  C K +  ++++V H R
Sbjct: 669 FSGSSN-LLSHHRIHSG---EKPYECSDCGKSFRQQSQLVVHRR 708



 Score =  120 bits (302), Expect = 5e-27
 Identities = 62/182 (34%), Positives = 92/182 (50%), Gaps = 3/182 (1%)

Query: 428 LQHLFIRKSFRPFKCLQCGKAFREKDKLDQHLRFHGREGNCPLTCDLCNKGFISSTSLES 487
           + H  I    +P++C++CGK+FR    L  H R H   G  P  C  C K F  S  L +
Sbjct: 536 ITHQRIHTGEKPYQCIECGKSFRWNSNLVIHQRIH--TGEKPYDCTHCGKSFSQSYQLVA 593

Query: 488 HMKLHSDQKTYSCIFCPESFDRLDLLKDHVAIHINDGYFTCPTCKKRFPDFIQVKKHVRS 547
           H + H+ +K Y C  C ++F+R   L  H+ IH  +  + C  C K F     +  H R+
Sbjct: 594 HKRTHTGEKPYECNECGKAFNRSTQLIRHLQIHTGEKPYKCNQCNKAFARSSYLVMHQRT 653

Query: 548 FHSEKIYQCTECDKAFCRPDKLRLHMLRHSDRKDFLCSTCGKQFKRKDKLREHMQRMHNP 607
              EK ++C++C KAF     L  H   HS  K + CS CGK F+++ +L  H +R H  
Sbjct: 654 HTGEKPFECSQCGKAFSGSSNLLSHHRIHSGEKPYECSDCGKSFRQQSQLVVH-RRTHTG 712

Query: 608 ER 609
           E+
Sbjct: 713 EK 714



 Score =  114 bits (286), Expect = 4e-25
 Identities = 95/345 (27%), Positives = 137/345 (39%), Gaps = 52/345 (15%)

Query: 433 IRKSFRPFKCLQCGKAFREKDKLDQHLRFHGREGNCPLTCDLCNKGFISSTSLESHMKLH 492
           I+ + +P  C QCGK+F     +  H R H   G  P  C  C K F  S  L  H + H
Sbjct: 347 IQTTEKPSVCNQCGKSFSCCKLI--HQRTH--TGEKPFECTQCGKSFSQSYDLVIHQRTH 402

Query: 493 SDQKTYSCIFCPESFDRLDLLKDHVAIHINDGYFTCPTCKKRFPDFIQVKKHVRSFHSEK 552
           + +K Y C  C +SF +   L  H  IH  +  + C  C+K F     +  H R    EK
Sbjct: 403 TGEKPYECDLCGKSFTQRSKLITHQRIHTGEKPYQCIECRKSFRWNSNLIVHQRIHTGEK 462

Query: 553 IYQCTECDKAFCRPDKLRLHMLRHSDRKDFLCSTCGKQFKRKDKLREHMQRMHNPEREAK 612
            Y+CT C K+F +  +L  H   H+  K F C+ CGK F +K  L  H QR H  E+   
Sbjct: 463 PYECTHCGKSFSQSYELVTHKRTHTGEKPFKCTQCGKSFSQKYDLVVH-QRTHTGEK--- 518

Query: 613 KADRISRSKTFKPRITSTDYDSFTFKCRLCMMGFRRRGMLVNHLSKRHPDMKIEEVPE-- 670
                                   ++C LC   F +   L+ H  + H   K  +  E  
Sbjct: 519 -----------------------PYECNLCGKSFSQSSKLITH-QRIHTGEKPYQCIECG 554

Query: 671 ----------LTLPIIKPNRDYFCQYCDKVYKSASKRKAHILKNHPGAELPPSIRKLRPA 720
                     +   I    + Y C +C K +  + +  AH  + H G E P    +   A
Sbjct: 555 KSFRWNSNLVIHQRIHTGEKPYDCTHCGKSFSQSYQLVAH-KRTHTG-EKPYECNECGKA 612

Query: 721 GPGEPDPMLSTHTQL-TGTIATPPVCCPHCSKQYSSKTKMVQHIR 764
                   L  H Q+ TG     P  C  C+K ++  + +V H R
Sbjct: 613 --FNRSTQLIRHLQIHTG---EKPYKCNQCNKAFARSSYLVMHQR 652



 Score = 72.4 bits (176), Expect = 2e-12
 Identities = 83/354 (23%), Positives = 130/354 (36%), Gaps = 62/354 (17%)

Query: 459 LRFHGREGNCPLTCDLCNKG--FISSTSLESHMKLHSDQKTYSCIFCPE----------- 505
           L FHGR  +   + D  + G  F  S SL     +H  +  Y C  C E           
Sbjct: 257 LCFHGRTFSVKKSDDCKDYGNLFSHSVSLNEQKPVHFGKSQYECDECRETCSESLCLVQT 316

Query: 506 -----------------SFDRLDLLKDHVAIHINDGYFTCPTCKKRFPDFIQVKKHVRSF 548
                            +F       D   I   +    C  C K F     +  H R+ 
Sbjct: 317 ERSGPGETPFRCEERCAAFPMASSFSDCNIIQTTEKPSVCNQCGKSFSCCKLI--HQRTH 374

Query: 549 HSEKIYQCTECDKAFCRPDKLRLHMLRHSDRKDFLCSTCGKQFKRKDKLREHMQRMHNPE 608
             EK ++CT+C K+F +   L +H   H+  K + C  CGK F ++ KL  H QR+H  E
Sbjct: 375 TGEKPFECTQCGKSFSQSYDLVIHQRTHTGEKPYECDLCGKSFTQRSKLITH-QRIHTGE 433

Query: 609 R-----EAKKADRISRSKTFKPRITSTDYDSFTFKCRLCMMGFRRRGMLVNHLSKRHPDM 663
           +     E +K+ R + +     RI + +     ++C  C   F +   LV H  + H   
Sbjct: 434 KPYQCIECRKSFRWNSNLIVHQRIHTGEK---PYECTHCGKSFSQSYELVTH-KRTHTGE 489

Query: 664 KIEEVPELTLPIIKP------------NRDYFCQYCDKVYKSASKRKAHILKNHPGAELP 711
           K  +  +      +              + Y C  C K +  +SK   H  + H G +  
Sbjct: 490 KPFKCTQCGKSFSQKYDLVVHQRTHTGEKPYECNLCGKSFSQSSKLITH-QRIHTGEK-- 546

Query: 712 PSIRKLRPAGPGEPDPMLSTHTQL-TGTIATPPVCCPHCSKQYSSKTKMVQHIR 764
              + +        +  L  H ++ TG     P  C HC K +S   ++V H R
Sbjct: 547 -PYQCIECGKSFRWNSNLVIHQRIHTG---EKPYDCTHCGKSFSQSYQLVAHKR 596


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.316    0.132    0.398 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 44,780,555
Number of Sequences: 37866
Number of extensions: 2390286
Number of successful extensions: 67796
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 1375
Number of HSP's successfully gapped in prelim test: 181
Number of HSP's that attempted gapping in prelim test: 18432
Number of HSP's gapped (non-prelim): 21823
length of query: 1023
length of database: 18,247,518
effective HSP length: 112
effective length of query: 911
effective length of database: 14,006,526
effective search space: 12759945186
effective search space used: 12759945186
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 67 (30.4 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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