Search of human proteins with 40316845

Search of human proteins with 40316845

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|40316845 solute carrier family 23 (nucleobase transporters),
member 2 [Homo sapiens]
         (650 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|44680148 solute carrier family 23 (nucleobase transporters), ...  1308   0.0  
gi|40316845 solute carrier family 23 (nucleobase transporters), ...  1308   0.0  
gi|44680145 solute carrier family 23 (nucleobase transporters), ...   786   0.0  
gi|44680143 solute carrier family 23 (nucleobase transporters), ...   780   0.0  
gi|222080105 solute carrier family 23 (nucleobase transporters),...   279   5e-75
gi|222080107 solute carrier family 23 (nucleobase transporters),...   279   7e-75
gi|158635944 solute carrier family 23 (nucleobase transporters),...   106   6e-23
gi|196123590 NADH dehydrogenase subunit 6 [Homo sapiens neandert...    34   0.48 
gi|251831118 NADH dehydrogenase subunit 6 [Homo sapiens]               34   0.48 
gi|5730045 solute carrier family 16, member 2 [Homo sapiens]           32   1.8  
gi|18699730 solute carrier family 16, member 10 [Homo sapiens]         32   2.4  
gi|122939153 nicotinamide nucleotide transhydrogenase [Homo sapi...    32   2.4  
gi|122939155 nicotinamide nucleotide transhydrogenase [Homo sapi...    32   2.4  
gi|221316645 UBA domain containing 2 isoform 1 [Homo sapiens]          31   4.1  
gi|134244587 endothelial differentiation, sphingolipid G-protein...    30   7.0  
gi|14150098 transmembrane protein 79 [Homo sapiens]                    30   7.0  

>gi|44680148 solute carrier family 23 (nucleobase transporters),
           member 2 [Homo sapiens]
          Length = 650

 Score = 1308 bits (3384), Expect = 0.0
 Identities = 650/650 (100%), Positives = 650/650 (100%)

Query: 1   MMGIGKNTTSKSMEAGSSTEGKYEDEAKHPAFFTLPVVINGGATSSGEQDNEDTELMAIY 60
           MMGIGKNTTSKSMEAGSSTEGKYEDEAKHPAFFTLPVVINGGATSSGEQDNEDTELMAIY
Sbjct: 1   MMGIGKNTTSKSMEAGSSTEGKYEDEAKHPAFFTLPVVINGGATSSGEQDNEDTELMAIY 60

Query: 61  TTENGIAEKSSLAETLDSTGSLDPQRSDMIYTIEDVPPWYLCIFLGLQHYLTCFSGTIAV 120
           TTENGIAEKSSLAETLDSTGSLDPQRSDMIYTIEDVPPWYLCIFLGLQHYLTCFSGTIAV
Sbjct: 61  TTENGIAEKSSLAETLDSTGSLDPQRSDMIYTIEDVPPWYLCIFLGLQHYLTCFSGTIAV 120

Query: 121 PFLLADAMCVGYDQWATSQLIGTIFFCVGITTLLQTTFGCRLPLFQASAFAFLAPARAIL 180
           PFLLADAMCVGYDQWATSQLIGTIFFCVGITTLLQTTFGCRLPLFQASAFAFLAPARAIL
Sbjct: 121 PFLLADAMCVGYDQWATSQLIGTIFFCVGITTLLQTTFGCRLPLFQASAFAFLAPARAIL 180

Query: 181 SLDKWKCNTTDVSVANGTAELLHTEHIWYPRIREIQGAIIMSSLIEVVIGLLGLPGALLK 240
           SLDKWKCNTTDVSVANGTAELLHTEHIWYPRIREIQGAIIMSSLIEVVIGLLGLPGALLK
Sbjct: 181 SLDKWKCNTTDVSVANGTAELLHTEHIWYPRIREIQGAIIMSSLIEVVIGLLGLPGALLK 240

Query: 241 YIGPLTITPTVALIGLSGFQAAGERAGKHWGIAMLTIFLVLLFSQYARNVKFPLPIYKSK 300
           YIGPLTITPTVALIGLSGFQAAGERAGKHWGIAMLTIFLVLLFSQYARNVKFPLPIYKSK
Sbjct: 241 YIGPLTITPTVALIGLSGFQAAGERAGKHWGIAMLTIFLVLLFSQYARNVKFPLPIYKSK 300

Query: 301 KGWTAYKLQLFKMFPIILAILVSWLLCFIFTVTDVFPPDSTKYGFYARTDARQGVLLVAP 360
           KGWTAYKLQLFKMFPIILAILVSWLLCFIFTVTDVFPPDSTKYGFYARTDARQGVLLVAP
Sbjct: 301 KGWTAYKLQLFKMFPIILAILVSWLLCFIFTVTDVFPPDSTKYGFYARTDARQGVLLVAP 360

Query: 361 WFKVPYPFQWGLPTVSAAGVIGMLSAVVASIIESIGDYYACARLSCAPPPPIHAINRGIF 420
           WFKVPYPFQWGLPTVSAAGVIGMLSAVVASIIESIGDYYACARLSCAPPPPIHAINRGIF
Sbjct: 361 WFKVPYPFQWGLPTVSAAGVIGMLSAVVASIIESIGDYYACARLSCAPPPPIHAINRGIF 420

Query: 421 VEGLSCVLDGIFGTGNGSTSSSPNIGVLGITKVGSRRVIQCGAALMLALGMIGKFSALFA 480
           VEGLSCVLDGIFGTGNGSTSSSPNIGVLGITKVGSRRVIQCGAALMLALGMIGKFSALFA
Sbjct: 421 VEGLSCVLDGIFGTGNGSTSSSPNIGVLGITKVGSRRVIQCGAALMLALGMIGKFSALFA 480

Query: 481 SLPDPVLGALFCTLFGMITAVGLSNLQFIDLNSSRNLFVLGFSIFFGLVLPSYLRQNPLV 540
           SLPDPVLGALFCTLFGMITAVGLSNLQFIDLNSSRNLFVLGFSIFFGLVLPSYLRQNPLV
Sbjct: 481 SLPDPVLGALFCTLFGMITAVGLSNLQFIDLNSSRNLFVLGFSIFFGLVLPSYLRQNPLV 540

Query: 541 TGITGIDQVLNVLLTTAMFVGGCVAFILDNTIPGTPEERGIRKWKKGVGKGNKSLDGMES 600
           TGITGIDQVLNVLLTTAMFVGGCVAFILDNTIPGTPEERGIRKWKKGVGKGNKSLDGMES
Sbjct: 541 TGITGIDQVLNVLLTTAMFVGGCVAFILDNTIPGTPEERGIRKWKKGVGKGNKSLDGMES 600

Query: 601 YNLPFGMNIIKKYRCFSYLPISPTFVGYTWKGLRKSDNSRSSDEDSQATG 650
           YNLPFGMNIIKKYRCFSYLPISPTFVGYTWKGLRKSDNSRSSDEDSQATG
Sbjct: 601 YNLPFGMNIIKKYRCFSYLPISPTFVGYTWKGLRKSDNSRSSDEDSQATG 650


>gi|40316845 solute carrier family 23 (nucleobase transporters),
           member 2 [Homo sapiens]
          Length = 650

 Score = 1308 bits (3384), Expect = 0.0
 Identities = 650/650 (100%), Positives = 650/650 (100%)

Query: 1   MMGIGKNTTSKSMEAGSSTEGKYEDEAKHPAFFTLPVVINGGATSSGEQDNEDTELMAIY 60
           MMGIGKNTTSKSMEAGSSTEGKYEDEAKHPAFFTLPVVINGGATSSGEQDNEDTELMAIY
Sbjct: 1   MMGIGKNTTSKSMEAGSSTEGKYEDEAKHPAFFTLPVVINGGATSSGEQDNEDTELMAIY 60

Query: 61  TTENGIAEKSSLAETLDSTGSLDPQRSDMIYTIEDVPPWYLCIFLGLQHYLTCFSGTIAV 120
           TTENGIAEKSSLAETLDSTGSLDPQRSDMIYTIEDVPPWYLCIFLGLQHYLTCFSGTIAV
Sbjct: 61  TTENGIAEKSSLAETLDSTGSLDPQRSDMIYTIEDVPPWYLCIFLGLQHYLTCFSGTIAV 120

Query: 121 PFLLADAMCVGYDQWATSQLIGTIFFCVGITTLLQTTFGCRLPLFQASAFAFLAPARAIL 180
           PFLLADAMCVGYDQWATSQLIGTIFFCVGITTLLQTTFGCRLPLFQASAFAFLAPARAIL
Sbjct: 121 PFLLADAMCVGYDQWATSQLIGTIFFCVGITTLLQTTFGCRLPLFQASAFAFLAPARAIL 180

Query: 181 SLDKWKCNTTDVSVANGTAELLHTEHIWYPRIREIQGAIIMSSLIEVVIGLLGLPGALLK 240
           SLDKWKCNTTDVSVANGTAELLHTEHIWYPRIREIQGAIIMSSLIEVVIGLLGLPGALLK
Sbjct: 181 SLDKWKCNTTDVSVANGTAELLHTEHIWYPRIREIQGAIIMSSLIEVVIGLLGLPGALLK 240

Query: 241 YIGPLTITPTVALIGLSGFQAAGERAGKHWGIAMLTIFLVLLFSQYARNVKFPLPIYKSK 300
           YIGPLTITPTVALIGLSGFQAAGERAGKHWGIAMLTIFLVLLFSQYARNVKFPLPIYKSK
Sbjct: 241 YIGPLTITPTVALIGLSGFQAAGERAGKHWGIAMLTIFLVLLFSQYARNVKFPLPIYKSK 300

Query: 301 KGWTAYKLQLFKMFPIILAILVSWLLCFIFTVTDVFPPDSTKYGFYARTDARQGVLLVAP 360
           KGWTAYKLQLFKMFPIILAILVSWLLCFIFTVTDVFPPDSTKYGFYARTDARQGVLLVAP
Sbjct: 301 KGWTAYKLQLFKMFPIILAILVSWLLCFIFTVTDVFPPDSTKYGFYARTDARQGVLLVAP 360

Query: 361 WFKVPYPFQWGLPTVSAAGVIGMLSAVVASIIESIGDYYACARLSCAPPPPIHAINRGIF 420
           WFKVPYPFQWGLPTVSAAGVIGMLSAVVASIIESIGDYYACARLSCAPPPPIHAINRGIF
Sbjct: 361 WFKVPYPFQWGLPTVSAAGVIGMLSAVVASIIESIGDYYACARLSCAPPPPIHAINRGIF 420

Query: 421 VEGLSCVLDGIFGTGNGSTSSSPNIGVLGITKVGSRRVIQCGAALMLALGMIGKFSALFA 480
           VEGLSCVLDGIFGTGNGSTSSSPNIGVLGITKVGSRRVIQCGAALMLALGMIGKFSALFA
Sbjct: 421 VEGLSCVLDGIFGTGNGSTSSSPNIGVLGITKVGSRRVIQCGAALMLALGMIGKFSALFA 480

Query: 481 SLPDPVLGALFCTLFGMITAVGLSNLQFIDLNSSRNLFVLGFSIFFGLVLPSYLRQNPLV 540
           SLPDPVLGALFCTLFGMITAVGLSNLQFIDLNSSRNLFVLGFSIFFGLVLPSYLRQNPLV
Sbjct: 481 SLPDPVLGALFCTLFGMITAVGLSNLQFIDLNSSRNLFVLGFSIFFGLVLPSYLRQNPLV 540

Query: 541 TGITGIDQVLNVLLTTAMFVGGCVAFILDNTIPGTPEERGIRKWKKGVGKGNKSLDGMES 600
           TGITGIDQVLNVLLTTAMFVGGCVAFILDNTIPGTPEERGIRKWKKGVGKGNKSLDGMES
Sbjct: 541 TGITGIDQVLNVLLTTAMFVGGCVAFILDNTIPGTPEERGIRKWKKGVGKGNKSLDGMES 600

Query: 601 YNLPFGMNIIKKYRCFSYLPISPTFVGYTWKGLRKSDNSRSSDEDSQATG 650
           YNLPFGMNIIKKYRCFSYLPISPTFVGYTWKGLRKSDNSRSSDEDSQATG
Sbjct: 601 YNLPFGMNIIKKYRCFSYLPISPTFVGYTWKGLRKSDNSRSSDEDSQATG 650


>gi|44680145 solute carrier family 23 (nucleobase transporters),
           member 1 isoform a [Homo sapiens]
          Length = 598

 Score =  786 bits (2029), Expect = 0.0
 Identities = 373/544 (68%), Positives = 449/544 (82%), Gaps = 3/544 (0%)

Query: 88  DMIYTIEDVPPWYLCIFLGLQHYLTCFSGTIAVPFLLADAMCVGYDQWATSQLIGTIFFC 147
           DM+Y IEDVPPWYLCI LG QHYLTCFSGTIAVPFLLA+A+CVG+DQ   SQLIGTIF C
Sbjct: 30  DMLYKIEDVPPWYLCILLGFQHYLTCFSGTIAVPFLLAEALCVGHDQHMVSQLIGTIFTC 89

Query: 148 VGITTLLQTTFGCRLPLFQASAFAFLAPARAILSLDKWKCNTTDVSVANGTAELLHTEHI 207
           VGITTL+QTT G RLPLFQASAFAFL PA+AIL+L++WKC   +    N +  L +T HI
Sbjct: 90  VGITTLIQTTVGIRLPLFQASAFAFLVPAKAILALERWKCPPEEEIYGNWSLPL-NTSHI 148

Query: 208 WYPRIREIQGAIIMSSLIEVVIGLLGLPGALLKYIGPLTITPTVALIGLSGFQAAGERAG 267
           W+PRIRE+QGAI++SS++EVVIGLLGLPGALL YIGPLT+TPTV+LIGLS FQAAG+RAG
Sbjct: 149 WHPRIREVQGAIMVSSVVEVVIGLLGLPGALLNYIGPLTVTPTVSLIGLSVFQAAGDRAG 208

Query: 268 KHWGIAMLTIFLVLLFSQYARNVKFPLPIYKSKKGWTAYKLQLFKMFPIILAILVSWLLC 327
            HWGI+  +I L++LFSQY RN+ F LP+Y+  KG T  ++Q+FKMFPI+LAI+  WLLC
Sbjct: 209 SHWGISACSILLIILFSQYLRNLTFLLPVYRWGKGLTLLRIQIFKMFPIMLAIMTVWLLC 268

Query: 328 FIFTVTDVFPPDSTKYGFYARTDARQGVLLVAPWFKVPYPFQWGLPTVSAAGVIGMLSAV 387
           ++ T+TDV P D   YGF ARTDAR  ++ +APW ++PYP QWGLPTV+AA V+GM SA 
Sbjct: 269 YVLTLTDVLPTDPKAYGFQARTDARGDIMAIAPWIRIPYPCQWGLPTVTAAAVLGMFSAT 328

Query: 388 VASIIESIGDYYACARLSCAPPPPIHAINRGIFVEGLSCVLDGIFGTGNGSTSSSPNIGV 447
           +A IIESIGDYYACARL+ APPPP+HAINRGIF EG+ C++ G+ GTGNGSTSSSPNIGV
Sbjct: 329 LAGIIESIGDYYACARLAGAPPPPVHAINRGIFTEGICCIIAGLLGTGNGSTSSSPNIGV 388

Query: 448 LGITKVGSRRVIQCGAALMLALGMIGKFSALFASLPDPVLGALFCTLFGMITAVGLSNLQ 507
           LGITKVGSRRV+Q GAA+ML LG IGKF+ALFASLPDP+LG +FCTLFGMITAVGLSNLQ
Sbjct: 389 LGITKVGSRRVVQYGAAIMLVLGTIGKFTALFASLPDPILGGMFCTLFGMITAVGLSNLQ 448

Query: 508 FIDLNSSRNLFVLGFSIFFGLVLPSYLRQNP--LVTGITGIDQVLNVLLTTAMFVGGCVA 565
           F+D+NSSRNLFVLGFS+FFGL LP+YL  NP  + TGI  +DQ+L VLLTT MFVGGC+A
Sbjct: 449 FVDMNSSRNLFVLGFSMFFGLTLPNYLESNPGAINTGILEVDQILIVLLTTEMFVGGCLA 508

Query: 566 FILDNTIPGTPEERGIRKWKKGVGKGNKSLDGMESYNLPFGMNIIKKYRCFSYLPISPTF 625
           FILDNT+PG+PEERG+ +WK G    +     ++SY+ P GM I+K+     Y+PI P F
Sbjct: 509 FILDNTVPGSPEERGLIQWKAGAHANSDMSSSLKSYDFPIGMGIVKRITFLKYIPICPVF 568

Query: 626 VGYT 629
            G++
Sbjct: 569 KGFS 572


>gi|44680143 solute carrier family 23 (nucleobase transporters),
           member 1 isoform b [Homo sapiens]
          Length = 602

 Score =  780 bits (2014), Expect = 0.0
 Identities = 373/548 (68%), Positives = 449/548 (81%), Gaps = 7/548 (1%)

Query: 88  DMIYTIEDVPPWYLCIFLGLQHYLTCFSGTIAVPFLLADAMCVGYDQWATSQLIGTIFFC 147
           DM+Y IEDVPPWYLCI LG QHYLTCFSGTIAVPFLLA+A+CVG+DQ   SQLIGTIF C
Sbjct: 30  DMLYKIEDVPPWYLCILLGFQHYLTCFSGTIAVPFLLAEALCVGHDQHMVSQLIGTIFTC 89

Query: 148 VGITTLLQTTFGCRLPLFQASAFAFLAPARAILSLDKWKCNTTDVSVANGTAELLHTEHI 207
           VGITTL+QTT G RLPLFQASAFAFL PA+AIL+L++WKC   +    N +  L +T HI
Sbjct: 90  VGITTLIQTTVGIRLPLFQASAFAFLVPAKAILALERWKCPPEEEIYGNWSLPL-NTSHI 148

Query: 208 WYPRIREI----QGAIIMSSLIEVVIGLLGLPGALLKYIGPLTITPTVALIGLSGFQAAG 263
           W+PRIRE+    QGAI++SS++EVVIGLLGLPGALL YIGPLT+TPTV+LIGLS FQAAG
Sbjct: 149 WHPRIREVGLHVQGAIMVSSVVEVVIGLLGLPGALLNYIGPLTVTPTVSLIGLSVFQAAG 208

Query: 264 ERAGKHWGIAMLTIFLVLLFSQYARNVKFPLPIYKSKKGWTAYKLQLFKMFPIILAILVS 323
           +RAG HWGI+  +I L++LFSQY RN+ F LP+Y+  KG T  ++Q+FKMFPI+LAI+  
Sbjct: 209 DRAGSHWGISACSILLIILFSQYLRNLTFLLPVYRWGKGLTLLRIQIFKMFPIMLAIMTV 268

Query: 324 WLLCFIFTVTDVFPPDSTKYGFYARTDARQGVLLVAPWFKVPYPFQWGLPTVSAAGVIGM 383
           WLLC++ T+TDV P D   YGF ARTDAR  ++ +APW ++PYP QWGLPTV+AA V+GM
Sbjct: 269 WLLCYVLTLTDVLPTDPKAYGFQARTDARGDIMAIAPWIRIPYPCQWGLPTVTAAAVLGM 328

Query: 384 LSAVVASIIESIGDYYACARLSCAPPPPIHAINRGIFVEGLSCVLDGIFGTGNGSTSSSP 443
            SA +A IIESIGDYYACARL+ APPPP+HAINRGIF EG+ C++ G+ GTGNGSTSSSP
Sbjct: 329 FSATLAGIIESIGDYYACARLAGAPPPPVHAINRGIFTEGICCIIAGLLGTGNGSTSSSP 388

Query: 444 NIGVLGITKVGSRRVIQCGAALMLALGMIGKFSALFASLPDPVLGALFCTLFGMITAVGL 503
           NIGVLGITKVGSRRV+Q GAA+ML LG IGKF+ALFASLPDP+LG +FCTLFGMITAVGL
Sbjct: 389 NIGVLGITKVGSRRVVQYGAAIMLVLGTIGKFTALFASLPDPILGGMFCTLFGMITAVGL 448

Query: 504 SNLQFIDLNSSRNLFVLGFSIFFGLVLPSYLRQNP--LVTGITGIDQVLNVLLTTAMFVG 561
           SNLQF+D+NSSRNLFVLGFS+FFGL LP+YL  NP  + TGI  +DQ+L VLLTT MFVG
Sbjct: 449 SNLQFVDMNSSRNLFVLGFSMFFGLTLPNYLESNPGAINTGILEVDQILIVLLTTEMFVG 508

Query: 562 GCVAFILDNTIPGTPEERGIRKWKKGVGKGNKSLDGMESYNLPFGMNIIKKYRCFSYLPI 621
           GC+AFILDNT+PG+PEERG+ +WK G    +     ++SY+ P GM I+K+     Y+PI
Sbjct: 509 GCLAFILDNTVPGSPEERGLIQWKAGAHANSDMSSSLKSYDFPIGMGIVKRITFLKYIPI 568

Query: 622 SPTFVGYT 629
            P F G++
Sbjct: 569 CPVFKGFS 576


>gi|222080105 solute carrier family 23 (nucleobase transporters),
           member 3 isoform 2 [Homo sapiens]
          Length = 610

 Score =  279 bits (714), Expect = 5e-75
 Identities = 162/496 (32%), Positives = 269/496 (54%), Gaps = 31/496 (6%)

Query: 98  PWYLCIFLGLQHYLTCFSGTIAVPFLLADAMCVGYDQWATSQLIGTIFFCVGITTLLQTT 157
           PW L   L LQH L   S       LL  ++  G   ++ SQL+ + FF  G++T+LQT 
Sbjct: 44  PWGLSCLLALQHVLVMASLLCVSHLLLLCSLSPGGLSYSPSQLLASSFFSCGMSTILQTW 103

Query: 158 FGCRLPLFQASAFAFLAPARAILSLDKWKCNTTDVSVANGTAELL---------HTEHIW 208
            G RLPL QA +  FL PA  + S    +   T      G + L+         H    W
Sbjct: 104 MGSRLPLVQAPSLEFLIPALVLTSQKLPRAIQTP-----GNSSLMLHLCRGPSCHGLGHW 158

Query: 209 YPRIREIQGAIIMSSLIEVVIGLLGLPGALLKYIGPLTITPTVALIGLSGFQAAGERAGK 268
              ++E+ GA+++S L++ ++GLLG PG +  + GPL + P++ + GLS  +   +    
Sbjct: 159 NTSLQEVSGAVVVSGLLQGMMGLLGSPGHVFPHCGPLVLAPSLVVAGLSAHREVAQFCFT 218

Query: 269 HWGIAMLTIFLVLLFSQYARNVKFPL-PIYKSKKGWTAYKLQLFKMFPIILAILVSWLLC 327
           HWG+A+L I L+++ SQ+  + +F + P  ++    T   L +F++  +++ +   W++ 
Sbjct: 219 HWGLALLVILLMVVCSQHLGSCQFHVCPWRRASTSSTHTPLPVFRLLSVLIPVACVWIVS 278

Query: 328 FIFTVTDVFPPDSTKYGFYARTDARQGVLLVAPWFKVPYPFQWGLPTVSAAGVIGMLSAV 387
             F    V P + +     A T A        PW  +P+P +W  P ++   +   +S  
Sbjct: 279 -AFVGFSVIPQELS-----APTKA--------PWIWLPHPGEWNWPLLTPRALAAGISMA 324

Query: 388 VASIIESIGDYYACARLSCAPPPPIHAINRGIFVEGLSCVLDGIFGTGNGSTSSSPNIGV 447
           +A+   S+G Y  C RL   PPPP HA +RG+ +EGL  VL G+ G+  G+ SS PN+G 
Sbjct: 325 LAASTSSLGCYALCGRLLHLPPPPPHACSRGLSLEGLGSVLAGLLGSPMGTASSFPNVGK 384

Query: 448 LGITKVGSRRVIQCGAALMLALGMIGKFSALFASLPDPVLGALFCTLFGMITAVGLSNLQ 507
           +G+ + GS++V      L + LG+  + + L  ++P PV+G +      ++ + G S+  
Sbjct: 385 VGLIQAGSQQVAHLVGLLCVGLGLSPRLAQLLTTIPLPVVGGVLGVTQAVVLSAGFSSFY 444

Query: 508 FIDLNSSRNLFVLGFSIFFGLVLPSYLRQNPLV--TGITGIDQVLNVLLTTAMFVGGCVA 565
             D++S RN+F++GFSIF  L+LP + R+ P++  TG + +D +L+ LLT  +F+ G   
Sbjct: 445 LADIDSGRNIFIVGFSIFMALLLPRWFREAPVLFSTGWSPLDVLLHSLLTQPIFLAGLSG 504

Query: 566 FILDNTIPGTPEERGI 581
           F+L+NTIPGT  ERG+
Sbjct: 505 FLLENTIPGTQLERGL 520


>gi|222080107 solute carrier family 23 (nucleobase transporters),
           member 3 isoform 3 [Homo sapiens]
          Length = 618

 Score =  279 bits (713), Expect = 7e-75
 Identities = 163/499 (32%), Positives = 270/499 (54%), Gaps = 29/499 (5%)

Query: 98  PWYLCIFLGLQHYLTCFSGTIAVPFLLADAMCVGYDQWATSQLIGTIFFCVGITTLLQTT 157
           PW L   L LQH L   S       LL  ++  G   ++ SQL+ + FF  G++T+LQT 
Sbjct: 44  PWGLSCLLALQHVLVMASLLCVSHLLLLCSLSPGGLSYSPSQLLASSFFSCGMSTILQTW 103

Query: 158 FGCRLPLFQASAFAFLAPARAILSLDKWKCNTTDVSV---ANGTAELL---------HTE 205
            G RLPL QA +  FL PA  + S    +   T  +    A   A L+         H  
Sbjct: 104 MGSRLPLVQAPSLEFLIPALVLTSQKLPRAIQTPGNCEHRARARASLMLHLCRGPSCHGL 163

Query: 206 HIWYPRIREIQGAIIMSSLIEVVIGLLGLPGALLKYIGPLTITPTVALIGLSGFQAAGER 265
             W   ++E+ GA+++S L++ ++GLLG PG +  + GPL + P++ + GLS  +   + 
Sbjct: 164 GHWNTSLQEVSGAVVVSGLLQGMMGLLGSPGHVFPHCGPLVLAPSLVVAGLSAHREVAQF 223

Query: 266 AGKHWGIAMLTIFLVLLFSQYARNVKFPL-PIYKSKKGWTAYKLQLFKMFPIILAILVSW 324
              HWG+A+L I L+++ SQ+  + +F + P  ++    T   L +F++  +++ +   W
Sbjct: 224 CFTHWGLALLVILLMVVCSQHLGSCQFHVCPWRRASTSSTHTPLPVFRLLSVLIPVACVW 283

Query: 325 LLCFIFTVTDVFPPDSTKYGFYARTDARQGVLLVAPWFKVPYPFQWGLPTVSAAGVIGML 384
           ++   F    V P + +     A T A        PW  +P+P +W  P ++   +   +
Sbjct: 284 IVS-AFVGFSVIPQELS-----APTKA--------PWIWLPHPGEWNWPLLTPRALAAGI 329

Query: 385 SAVVASIIESIGDYYACARLSCAPPPPIHAINRGIFVEGLSCVLDGIFGTGNGSTSSSPN 444
           S  +A+   S+G Y  C RL   PPPP HA +RG+ +EGL  VL G+ G+  G+ SS PN
Sbjct: 330 SMALAASTSSLGCYALCGRLLHLPPPPPHACSRGLSLEGLGSVLAGLLGSPMGTASSFPN 389

Query: 445 IGVLGITKVGSRRVIQCGAALMLALGMIGKFSALFASLPDPVLGALFCTLFGMITAVGLS 504
           +G +G+ + GS++V      L + LG+  + + L  ++P PV+G +      ++ + G S
Sbjct: 390 VGKVGLIQAGSQQVAHLVGLLCVGLGLSPRLAQLLTTIPLPVVGGVLGVTQAVVLSAGFS 449

Query: 505 NLQFIDLNSSRNLFVLGFSIFFGLVLPSYLRQNPLV--TGITGIDQVLNVLLTTAMFVGG 562
           +    D++S RN+F++GFSIF  L+LP + R+ P++  TG + +D +L+ LLT  +F+ G
Sbjct: 450 SFYLADIDSGRNIFIVGFSIFMALLLPRWFREAPVLFSTGWSPLDVLLHSLLTQPIFLAG 509

Query: 563 CVAFILDNTIPGTPEERGI 581
              F+L+NTIPGT  ERG+
Sbjct: 510 LSGFLLENTIPGTQLERGL 528


>gi|158635944 solute carrier family 23 (nucleobase transporters),
           member 3 isoform 1 [Homo sapiens]
          Length = 493

 Score =  106 bits (265), Expect = 6e-23
 Identities = 63/188 (33%), Positives = 97/188 (51%), Gaps = 14/188 (7%)

Query: 98  PWYLCIFLGLQHYLTCFSGTIAVPFLLADAMCVGYDQWATSQLIGTIFFCVGITTLLQTT 157
           PW L   L LQH L   S       LL  ++  G   ++ SQL+ + FF  G++T+LQT 
Sbjct: 44  PWGLSCLLALQHVLVMASLLCVSHLLLLCSLSPGGLSYSPSQLLASSFFSCGMSTILQTW 103

Query: 158 FGCRLPLFQASAFAFLAPARAILSLDKWKCNTTDVSVANGTAELL---------HTEHIW 208
            G RLPL QA +  FL PA  + S    +   T      G + L+         H    W
Sbjct: 104 MGSRLPLVQAPSLEFLIPALVLTSQKLPRAIQTP-----GNSSLMLHLCRGPSCHGLGHW 158

Query: 209 YPRIREIQGAIIMSSLIEVVIGLLGLPGALLKYIGPLTITPTVALIGLSGFQAAGERAGK 268
              ++E+ GA+++S L++ ++GLLG PG +  + GPL + P++ + GLS  +   +    
Sbjct: 159 NTSLQEVSGAVVVSGLLQGMMGLLGSPGHVFPHCGPLVLAPSLVVAGLSAHREVAQFCFT 218

Query: 269 HWGIAMLT 276
           HWG+A+LT
Sbjct: 219 HWGLALLT 226



 Score = 99.8 bits (247), Expect = 7e-21
 Identities = 49/134 (36%), Positives = 84/134 (62%), Gaps = 2/134 (1%)

Query: 450 ITKVGSRRVIQCGAALMLALGMIGKFSALFASLPDPVLGALFCTLFGMITAVGLSNLQFI 509
           +T+ GS++V      L + LG+  + + L  ++P PV+G +      ++ + G S+    
Sbjct: 270 LTQAGSQQVAHLVGLLCVGLGLSPRLAQLLTTIPLPVVGGVLGVTQAVVLSAGFSSFYLA 329

Query: 510 DLNSSRNLFVLGFSIFFGLVLPSYLRQNPLV--TGITGIDQVLNVLLTTAMFVGGCVAFI 567
           D++S RN+F++GFSIF  L+LP + R+ P++  TG + +D +L+ LLT  +F+ G   F+
Sbjct: 330 DIDSGRNIFIVGFSIFMALLLPRWFREAPVLFSTGWSPLDVLLHSLLTQPIFLAGLSGFL 389

Query: 568 LDNTIPGTPEERGI 581
           L+NTIPGT  ERG+
Sbjct: 390 LENTIPGTQLERGL 403


>gi|196123590 NADH dehydrogenase subunit 6 [Homo sapiens
           neanderthalensis]
          Length = 174

 Score = 33.9 bits (76), Expect = 0.48
 Identities = 27/100 (27%), Positives = 49/100 (49%), Gaps = 3/100 (3%)

Query: 463 AALMLALGMIGKFSALFASLPDPVLGALFCTLFGMITAVGLSNLQFIDLNSSRNLFVL-G 521
           A  +L++G++  F   F+S P P+ G L   + G++  V + N     +     L  L G
Sbjct: 4   ALFLLSVGLVMGFVG-FSSKPSPIYGGLVLIVSGVVGCVIILNFGGGYMGLMVFLIYLGG 62

Query: 522 FSIFFGLVLPSYLRQNPLVTGITGIDQVLNVLLTTAMFVG 561
             + FG      + + P   G +G++ +++VL+  AM VG
Sbjct: 63  MMVVFGYTTAMAIEEYPEAWG-SGVEVLVSVLVGLAMEVG 101


>gi|251831118 NADH dehydrogenase subunit 6 [Homo sapiens]
          Length = 174

 Score = 33.9 bits (76), Expect = 0.48
 Identities = 27/100 (27%), Positives = 49/100 (49%), Gaps = 3/100 (3%)

Query: 463 AALMLALGMIGKFSALFASLPDPVLGALFCTLFGMITAVGLSNLQFIDLNSSRNLFVL-G 521
           A  +L++G++  F   F+S P P+ G L   + G++  V + N     +     L  L G
Sbjct: 4   ALFLLSVGLVMGFVG-FSSKPSPIYGGLVLIVSGVVGCVIILNFGGGYMGLMVFLIYLGG 62

Query: 522 FSIFFGLVLPSYLRQNPLVTGITGIDQVLNVLLTTAMFVG 561
             + FG      + + P   G +G++ +++VL+  AM VG
Sbjct: 63  MMVVFGYTTAMAIEEYPEAWG-SGVEVLVSVLVGLAMEVG 101


>gi|5730045 solute carrier family 16, member 2 [Homo sapiens]
          Length = 613

 Score = 32.0 bits (71), Expect = 1.8
 Identities = 13/39 (33%), Positives = 20/39 (51%)

Query: 135 WATSQLIGTIFFCVGITTLLQTTFGCRLPLFQASAFAFL 173
           W  +  +G IFFC  I ++     GCR+     +A AF+
Sbjct: 219 WVGALAMGMIFFCSPIVSIFTDRLGCRITATAGAAVAFI 257


>gi|18699730 solute carrier family 16, member 10 [Homo sapiens]
          Length = 515

 Score = 31.6 bits (70), Expect = 2.4
 Identities = 14/39 (35%), Positives = 19/39 (48%)

Query: 135 WATSQLIGTIFFCVGITTLLQTTFGCRLPLFQASAFAFL 173
           W  S  +G IFFC  I ++    FGCR      +A  F+
Sbjct: 116 WVGSLSMGMIFFCCPIVSVFTDLFGCRKTAVVGAAVGFV 154


>gi|122939153 nicotinamide nucleotide transhydrogenase [Homo
           sapiens]
          Length = 1086

 Score = 31.6 bits (70), Expect = 2.4
 Identities = 15/53 (28%), Positives = 30/53 (56%)

Query: 216 QGAIIMSSLIEVVIGLLGLPGALLKYIGPLTITPTVALIGLSGFQAAGERAGK 268
           +G ++ ++L+ +V  L+G  GA+L YI  + +  ++A + L G+       GK
Sbjct: 849 EGFLLNNNLLTIVGALIGSSGAILSYIMCVAMNRSLANVILGGYGTTSTAGGK 901


>gi|122939155 nicotinamide nucleotide transhydrogenase [Homo
           sapiens]
          Length = 1086

 Score = 31.6 bits (70), Expect = 2.4
 Identities = 15/53 (28%), Positives = 30/53 (56%)

Query: 216 QGAIIMSSLIEVVIGLLGLPGALLKYIGPLTITPTVALIGLSGFQAAGERAGK 268
           +G ++ ++L+ +V  L+G  GA+L YI  + +  ++A + L G+       GK
Sbjct: 849 EGFLLNNNLLTIVGALIGSSGAILSYIMCVAMNRSLANVILGGYGTTSTAGGK 901


>gi|221316645 UBA domain containing 2 isoform 1 [Homo sapiens]
          Length = 344

 Score = 30.8 bits (68), Expect = 4.1
 Identities = 24/79 (30%), Positives = 39/79 (49%), Gaps = 7/79 (8%)

Query: 320 ILVSWLLCFIFTVTDVFPPDSTKY--GFYARTDARQGVLLVAPWFKVPYPFQWGLPTVSA 377
           +L SW+L  +F   D    ++ +Y  G  A ++   G L  AP F +  PF   +P V  
Sbjct: 96  LLGSWVLSALF---DFLLIEAMQYFFGITAASNLPSGFL--APVFALFVPFYCSIPRVQV 150

Query: 378 AGVIGMLSAVVASIIESIG 396
           A ++G LS    ++I  +G
Sbjct: 151 AQILGPLSITNKTLIYILG 169


>gi|134244587 endothelial differentiation, sphingolipid
           G-protein-coupled receptor, 5 [Homo sapiens]
          Length = 353

 Score = 30.0 bits (66), Expect = 7.0
 Identities = 33/119 (27%), Positives = 50/119 (42%), Gaps = 15/119 (12%)

Query: 222 SSLIEVVIGLLGLPGALLKYIGPLTITPTVALIGLSGFQAAGERAGKHWGIAMLTIFLVL 281
           S LI +V+G  GLP      +G L    TV  +             KH+ + ++TIF ++
Sbjct: 155 SWLISLVLG--GLPILGWNCLGHLEACSTVLPL-----------YAKHYVLCVVTIFSII 201

Query: 282 LFSQYARNVKFPLPIYKSKKGWTA-YKLQLFKMFPIILAI-LVSWLLCFIFTVTDVFPP 338
           L +  A  V+    +  S     A   L L K   I+L + +V WL  F   + D   P
Sbjct: 202 LLAIVALYVRIYCVVRSSHADMAAPQTLALLKTVTIVLGVFIVCWLPAFSILLLDYACP 260


>gi|14150098 transmembrane protein 79 [Homo sapiens]
          Length = 394

 Score = 30.0 bits (66), Expect = 7.0
 Identities = 26/94 (27%), Positives = 41/94 (43%), Gaps = 3/94 (3%)

Query: 273 AMLTIFLVLLFSQYARNVKFPLPIYKSKKGWTAYKLQ--LFKMFPIILAILVSWLLCFIF 330
           A L +F  LL+  YA  + F +P   +      Y L+  +F  FPI+L ILV  L    F
Sbjct: 206 AALILFPCLLYGAYAF-LPFDVPRLPTMSSRLIYTLRCGVFATFPIVLGILVYGLSLLCF 264

Query: 331 TVTDVFPPDSTKYGFYARTDARQGVLLVAPWFKV 364
           +    F     +   + R  A+   L +  +F +
Sbjct: 265 SALRPFGEPRREVEIHRRYVAQSVQLFILYFFNL 298


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.323    0.140    0.430 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 24,319,638
Number of Sequences: 37866
Number of extensions: 1082129
Number of successful extensions: 2192
Number of sequences better than 10.0: 16
Number of HSP's better than 10.0 without gapping: 11
Number of HSP's successfully gapped in prelim test: 5
Number of HSP's that attempted gapping in prelim test: 2167
Number of HSP's gapped (non-prelim): 17
length of query: 650
length of database: 18,247,518
effective HSP length: 109
effective length of query: 541
effective length of database: 14,120,124
effective search space: 7638987084
effective search space used: 7638987084
T: 11
A: 40
X1: 16 ( 7.5 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (22.0 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.