BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|38504673 serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 8 isoform a [Homo sapiens] (374 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|38504669 serine (or cysteine) proteinase inhibitor, clade B (... 755 0.0 gi|38504673 serine (or cysteine) proteinase inhibitor, clade B (... 755 0.0 gi|41152086 serine (or cysteine) proteinase inhibitor, clade B (... 501 e-142 gi|73623033 serine (or cysteine) proteinase inhibitor, clade B (... 485 e-137 gi|4758906 serpin peptidase inhibitor, clade B, member 9 [Homo s... 469 e-132 gi|13489087 serine (or cysteine) proteinase inhibitor, clade B (... 372 e-103 gi|219689110 serine (or cysteine) proteinase inhibitor, clade B ... 337 8e-93 gi|4505595 serine (or cysteine) proteinase inhibitor, clade B (o... 337 8e-93 gi|4826902 serine (or cysteine) proteinase inhibitor, clade B (o... 318 6e-87 gi|28076869 serine (or cysteine) proteinase inhibitor, clade B (... 311 5e-85 gi|5902072 serine (or cysteine) proteinase inhibitor, clade B (o... 309 2e-84 gi|156071456 serpin peptidase inhibitor, clade B, member 11 [Hom... 303 1e-82 gi|17998551 serine (or cysteine) proteinase inhibitor, clade B (... 295 3e-80 gi|8393956 serine (or cysteine) proteinase inhibitor, clade B (o... 284 8e-77 gi|167860126 serine (or cysteine) proteinase inhibitor, clade B ... 258 6e-69 gi|92859634 serine (or cysteine) proteinase inhibitor, clade B (... 253 1e-67 gi|4505149 serine (or cysteine) proteinase inhibitor, clade B (o... 253 1e-67 gi|4502261 serpin peptidase inhibitor, clade C, member 1 [Homo s... 234 7e-62 gi|170295807 neuroserpin precursor [Homo sapiens] 218 7e-57 gi|4826904 neuroserpin precursor [Homo sapiens] 218 7e-57 gi|5453886 serpin peptidase inhibitor, clade I (pancpin), member... 206 4e-53 gi|194018472 serine (or cysteine) proteinase inhibitor, clade A ... 186 2e-47 gi|110225347 serine (or cysteine) proteinase inhibitor, clade A ... 183 2e-46 gi|10835159 plasminogen activator inhibitor-1 [Homo sapiens] 182 3e-46 gi|73858566 heparin cofactor II precursor [Homo sapiens] 181 7e-46 gi|50659080 serpin peptidase inhibitor, clade A, member 3 precur... 177 1e-44 gi|189163542 serine proteinase inhibitor, clade A, member 1 [Hom... 177 1e-44 gi|189163540 serine proteinase inhibitor, clade A, member 1 [Hom... 177 1e-44 gi|189163538 serine proteinase inhibitor, clade A, member 1 [Hom... 177 1e-44 gi|189163536 serine proteinase inhibitor, clade A, member 1 [Hom... 177 1e-44 >gi|38504669 serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 8 isoform a [Homo sapiens] Length = 374 Score = 755 bits (1950), Expect = 0.0 Identities = 374/374 (100%), Positives = 374/374 (100%) Query: 1 MDDLCEANGTFAISLFKILGEEDNSRNVFFSPMSISSALAMVFMGAKGSTAAQMSQALCL 60 MDDLCEANGTFAISLFKILGEEDNSRNVFFSPMSISSALAMVFMGAKGSTAAQMSQALCL Sbjct: 1 MDDLCEANGTFAISLFKILGEEDNSRNVFFSPMSISSALAMVFMGAKGSTAAQMSQALCL 60 Query: 61 YKDGDIHRGFQSLLSEVNRTGTQYLLRTANRLFGEKTCDFLPDFKEYCQKFYQAELEELS 120 YKDGDIHRGFQSLLSEVNRTGTQYLLRTANRLFGEKTCDFLPDFKEYCQKFYQAELEELS Sbjct: 61 YKDGDIHRGFQSLLSEVNRTGTQYLLRTANRLFGEKTCDFLPDFKEYCQKFYQAELEELS 120 Query: 121 FAEDTEECRKHINDWVAEKTEGKISEVLDAGTVDPLTKLVLVNAIYFKGKWNEQFDRKYT 180 FAEDTEECRKHINDWVAEKTEGKISEVLDAGTVDPLTKLVLVNAIYFKGKWNEQFDRKYT Sbjct: 121 FAEDTEECRKHINDWVAEKTEGKISEVLDAGTVDPLTKLVLVNAIYFKGKWNEQFDRKYT 180 Query: 181 RGMLFKTNEEKKTVQMMFKEAKFKMGYADEVHTQVLELPYVEEELSMVILLPDDNTDLAV 240 RGMLFKTNEEKKTVQMMFKEAKFKMGYADEVHTQVLELPYVEEELSMVILLPDDNTDLAV Sbjct: 181 RGMLFKTNEEKKTVQMMFKEAKFKMGYADEVHTQVLELPYVEEELSMVILLPDDNTDLAV 240 Query: 241 VEKALTYEKFKAWTNSEKLTKSKVQVFLPRLKLEESYDLEPFLRRLGMIDAFDEAKADFS 300 VEKALTYEKFKAWTNSEKLTKSKVQVFLPRLKLEESYDLEPFLRRLGMIDAFDEAKADFS Sbjct: 241 VEKALTYEKFKAWTNSEKLTKSKVQVFLPRLKLEESYDLEPFLRRLGMIDAFDEAKADFS 300 Query: 301 GMSTEKNVPLSKVAHKCFVEVNEEGTEAAAATAVVRNSRCSRMEPRFCADHPFLFFIRHH 360 GMSTEKNVPLSKVAHKCFVEVNEEGTEAAAATAVVRNSRCSRMEPRFCADHPFLFFIRHH Sbjct: 301 GMSTEKNVPLSKVAHKCFVEVNEEGTEAAAATAVVRNSRCSRMEPRFCADHPFLFFIRHH 360 Query: 361 KTNCILFCGRFSSP 374 KTNCILFCGRFSSP Sbjct: 361 KTNCILFCGRFSSP 374 >gi|38504673 serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 8 isoform a [Homo sapiens] Length = 374 Score = 755 bits (1950), Expect = 0.0 Identities = 374/374 (100%), Positives = 374/374 (100%) Query: 1 MDDLCEANGTFAISLFKILGEEDNSRNVFFSPMSISSALAMVFMGAKGSTAAQMSQALCL 60 MDDLCEANGTFAISLFKILGEEDNSRNVFFSPMSISSALAMVFMGAKGSTAAQMSQALCL Sbjct: 1 MDDLCEANGTFAISLFKILGEEDNSRNVFFSPMSISSALAMVFMGAKGSTAAQMSQALCL 60 Query: 61 YKDGDIHRGFQSLLSEVNRTGTQYLLRTANRLFGEKTCDFLPDFKEYCQKFYQAELEELS 120 YKDGDIHRGFQSLLSEVNRTGTQYLLRTANRLFGEKTCDFLPDFKEYCQKFYQAELEELS Sbjct: 61 YKDGDIHRGFQSLLSEVNRTGTQYLLRTANRLFGEKTCDFLPDFKEYCQKFYQAELEELS 120 Query: 121 FAEDTEECRKHINDWVAEKTEGKISEVLDAGTVDPLTKLVLVNAIYFKGKWNEQFDRKYT 180 FAEDTEECRKHINDWVAEKTEGKISEVLDAGTVDPLTKLVLVNAIYFKGKWNEQFDRKYT Sbjct: 121 FAEDTEECRKHINDWVAEKTEGKISEVLDAGTVDPLTKLVLVNAIYFKGKWNEQFDRKYT 180 Query: 181 RGMLFKTNEEKKTVQMMFKEAKFKMGYADEVHTQVLELPYVEEELSMVILLPDDNTDLAV 240 RGMLFKTNEEKKTVQMMFKEAKFKMGYADEVHTQVLELPYVEEELSMVILLPDDNTDLAV Sbjct: 181 RGMLFKTNEEKKTVQMMFKEAKFKMGYADEVHTQVLELPYVEEELSMVILLPDDNTDLAV 240 Query: 241 VEKALTYEKFKAWTNSEKLTKSKVQVFLPRLKLEESYDLEPFLRRLGMIDAFDEAKADFS 300 VEKALTYEKFKAWTNSEKLTKSKVQVFLPRLKLEESYDLEPFLRRLGMIDAFDEAKADFS Sbjct: 241 VEKALTYEKFKAWTNSEKLTKSKVQVFLPRLKLEESYDLEPFLRRLGMIDAFDEAKADFS 300 Query: 301 GMSTEKNVPLSKVAHKCFVEVNEEGTEAAAATAVVRNSRCSRMEPRFCADHPFLFFIRHH 360 GMSTEKNVPLSKVAHKCFVEVNEEGTEAAAATAVVRNSRCSRMEPRFCADHPFLFFIRHH Sbjct: 301 GMSTEKNVPLSKVAHKCFVEVNEEGTEAAAATAVVRNSRCSRMEPRFCADHPFLFFIRHH 360 Query: 361 KTNCILFCGRFSSP 374 KTNCILFCGRFSSP Sbjct: 361 KTNCILFCGRFSSP 374 >gi|41152086 serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 6 [Homo sapiens] Length = 376 Score = 501 bits (1291), Expect = e-142 Identities = 253/378 (66%), Positives = 303/378 (80%), Gaps = 6/378 (1%) Query: 1 MDDLCEANGTFAISLFKILGEEDNSRNVFFSPMSISSALAMVFMGAKGSTAAQMSQALCL 60 MD L EANGTFA++L K LG+ DNS+NVFFSPMS+S ALAMV+MGAKG+TAAQM+Q L Sbjct: 1 MDVLAEANGTFALNLLKTLGK-DNSKNVFFSPMSMSCALAMVYMGAKGNTAAQMAQILSF 59 Query: 61 YKDG---DIHRGFQSLLSEVNRTGTQYLLRTANRLFGEKTCDFLPDFKEYCQKFYQAELE 117 K G DIH+GFQSLL+EVN+TGTQYLLR ANRLFGEK+CDFL F++ CQKFYQAE+E Sbjct: 60 NKSGGGGDIHQGFQSLLTEVNKTGTQYLLRMANRLFGEKSCDFLSSFRDSCQKFYQAEME 119 Query: 118 ELSFAEDTEECRKHINDWVAEKTEGKISEVLDAGTVDPLTKLVLVNAIYFKGKWNEQFDR 177 EL F E+ RKHIN WVAEKTEGKI+E+L G+VDPLT+LVLVNA+YF+G W+EQFD+ Sbjct: 120 ELDFISAVEKSRKHINTWVAEKTEGKIAELLSPGSVDPLTRLVLVNAVYFRGNWDEQFDK 179 Query: 178 KYTRGMLFKTNE-EKKTVQMMFKEAKFKMGYADEVHTQVLELPYVEEELSMVILLPDDNT 236 + T LFK ++ E+K VQMMFK++ FK Y E+ TQ+L LPYV +EL+M+I+LPD+ T Sbjct: 180 ENTEERLFKVSKNEEKPVQMMFKQSTFKKTYIGEIFTQILVLPYVGKELNMIIMLPDETT 239 Query: 237 DLAVVEKALTYEKFKAWTNSEKLTKSKVQVFLPRLKLEESYDLEPFLRRLGMIDAFDEAK 296 DL VEK LTYEKF WT + + + +V+V LPR KLEESYD+E LR LGM DAF+ K Sbjct: 240 DLRTVEKELTYEKFVEWTRLDMMDEEEVEVSLPRFKLEESYDMESVLRNLGMTDAFELGK 299 Query: 297 ADFSGMSTEKNVPLSKVAHKCFVEVNEEGTEAAAATAVVRNSRCSRMEPRFCADHPFLFF 356 ADFSGMS + ++ LSKV HK FVEVNEEGTEAAAATA + RC+R PRFCADHPFLFF Sbjct: 300 ADFSGMS-QTDLSLSKVVHKSFVEVNEEGTEAAAATAAIMMMRCARFVPRFCADHPFLFF 358 Query: 357 IRHHKTNCILFCGRFSSP 374 I+H KTN ILFCGRFSSP Sbjct: 359 IQHSKTNGILFCGRFSSP 376 >gi|73623033 serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 8 isoform b [Homo sapiens] Length = 242 Score = 485 bits (1248), Expect = e-137 Identities = 241/242 (99%), Positives = 241/242 (99%) Query: 1 MDDLCEANGTFAISLFKILGEEDNSRNVFFSPMSISSALAMVFMGAKGSTAAQMSQALCL 60 MDDLCEANGTFAISLFKILGEEDNSRNVFFSPMSISSALAMVFMGAKGSTAAQMSQALCL Sbjct: 1 MDDLCEANGTFAISLFKILGEEDNSRNVFFSPMSISSALAMVFMGAKGSTAAQMSQALCL 60 Query: 61 YKDGDIHRGFQSLLSEVNRTGTQYLLRTANRLFGEKTCDFLPDFKEYCQKFYQAELEELS 120 YKDGDIHRGFQSLLSEVNRTGTQYLLRTANRLFGEKTCDFLPDFKEYCQKFYQAELEELS Sbjct: 61 YKDGDIHRGFQSLLSEVNRTGTQYLLRTANRLFGEKTCDFLPDFKEYCQKFYQAELEELS 120 Query: 121 FAEDTEECRKHINDWVAEKTEGKISEVLDAGTVDPLTKLVLVNAIYFKGKWNEQFDRKYT 180 FAEDTEECRKHINDWVAEKTEGKISEVLDAGTVDPLTKLVLVNAIYFKGKWNEQFDRKYT Sbjct: 121 FAEDTEECRKHINDWVAEKTEGKISEVLDAGTVDPLTKLVLVNAIYFKGKWNEQFDRKYT 180 Query: 181 RGMLFKTNEEKKTVQMMFKEAKFKMGYADEVHTQVLELPYVEEELSMVILLPDDNTDLAV 240 RGMLFKTNEEKKTVQMMFKEAKFKMGYADEVHTQVLELPYVEEELSMVILLPDDNTDLAV Sbjct: 181 RGMLFKTNEEKKTVQMMFKEAKFKMGYADEVHTQVLELPYVEEELSMVILLPDDNTDLAV 240 Query: 241 VE 242 E Sbjct: 241 KE 242 >gi|4758906 serpin peptidase inhibitor, clade B, member 9 [Homo sapiens] Length = 376 Score = 469 bits (1206), Expect = e-132 Identities = 235/376 (62%), Positives = 288/376 (76%), Gaps = 2/376 (0%) Query: 1 MDDLCEANGTFAISLFKILGEEDNSRNVFFSPMSISSALAMVFMGAKGSTAAQMSQALCL 60 M+ L A+GTFAI L KIL +++ S NVF SP+SISSALAMV +GAKG+TA QM+QAL L Sbjct: 1 METLSNASGTFAIRLLKILCQDNPSHNVFCSPVSISSALAMVLLGAKGNTATQMAQALSL 60 Query: 61 YKDGDIHRGFQSLLSEVNRTGTQYLLRTANRLFGEKTCDFLPDFKEYCQKFYQAELEELS 120 + DIHR FQSLL+EVN+ GTQYLLRTANRLFGEKTC FL FKE C +FY AEL+ELS Sbjct: 61 NTEEDIHRAFQSLLTEVNKAGTQYLLRTANRLFGEKTCQFLSTFKESCLQFYHAELKELS 120 Query: 121 FAEDTEECRKHINDWVAEKTEGKISEVLDAGTVDPLTKLVLVNAIYFKGKWNEQFDRKYT 180 F EE RKHIN WV++KTEGKI E+L ++D T+LVLVNAIYFKGKWNE FD YT Sbjct: 121 FIRAAEESRKHINTWVSKKTEGKIEELLPGSSIDAETRLVLVNAIYFKGKWNEPFDETYT 180 Query: 181 RGMLFKTN-EEKKTVQMMFKEAKFKMGYADEVHTQVLELPYVEEELSMVILLPDDNTDLA 239 R M FK N EE++ VQMM++EA FK+ + EV Q+LELPY +ELS+++LLPDD +L+ Sbjct: 181 REMPFKINQEEQRPVQMMYQEATFKLAHVGEVRAQLLELPYARKELSLLVLLPDDGVELS 240 Query: 240 VVEKALTYEKFKAWTNSEKLTKSKVQVFLPRLKLEESYDLEPFLRRLGMIDAFDEAKADF 299 VEK+LT+EK AWT + + ++V+V LP+ KL+E YD+E LR LG++DAF + KAD Sbjct: 241 TVEKSLTFEKLTAWTKPDCMKSTEVEVLLPKFKLQEDYDMESVLRHLGIVDAFQQGKADL 300 Query: 300 SGMSTEKNVPLSKVAHKCFVEVNEEGTEAAAATA-VVRNSRCSRMEPRFCADHPFLFFIR 358 S MS E+++ LSK HK FVEVNEEGTEAAAA++ V C PRFCADHPFLFFIR Sbjct: 301 SAMSAERDLCLSKFVHKSFVEVNEEGTEAAAASSCFVVAECCMESGPRFCADHPFLFFIR 360 Query: 359 HHKTNCILFCGRFSSP 374 H++ N ILFCGRFSSP Sbjct: 361 HNRANSILFCGRFSSP 376 >gi|13489087 serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 1 [Homo sapiens] Length = 379 Score = 372 bits (956), Expect = e-103 Identities = 197/379 (51%), Positives = 258/379 (68%), Gaps = 5/379 (1%) Query: 1 MDDLCEANGTFAISLFKILGEEDNSRNVFFSPMSISSALAMVFMGAKGSTAAQMSQALCL 60 M+ L AN FA+ LF L E + + N+F SP SISSA+AMVF+G +G+TAAQ+S+ Sbjct: 1 MEQLSSANTRFALDLFLALSENNPAGNIFISPFSISSAMAMVFLGTRGNTAAQLSKTFHF 60 Query: 61 YKDGDIHRGFQSLLSEVNRTGTQYLLRTANRLFGEKTCDFLPDFKEYCQKFYQAELEELS 120 ++H FQSL +++N+ G Y+L+ ANRL+GEKT +FLP+F QK Y A+L + Sbjct: 61 NTVEEVHSRFQSLNADINKRGASYILKLANRLYGEKTYNFLPEFLVSTQKTYGADLASVD 120 Query: 121 FAEDTEECRKHINDWVAEKTEGKISEVLDAGTVDPLTKLVLVNAIYFKGKWNEQFDRKYT 180 F +E+ RK IN WV +TEGKI E+L +G VD +TKLVLVNAIYFKG W ++F ++ T Sbjct: 121 FQHASEDARKTINQWVKGQTEGKIPELLASGMVDNMTKLVLVNAIYFKGNWKDKFMKEAT 180 Query: 181 RGMLFKTN-EEKKTVQMMFKEAKFKMGYADEVHTQVLELPYVEEELSMVILLPDD----N 235 F+ N +++KTV+MM+++ KF GY +++ +VLELPY EELSMVILLPDD + Sbjct: 181 TNAPFRLNKKDRKTVKMMYQKKKFAYGYIEDLKCRVLELPYQGEELSMVILLPDDIEDES 240 Query: 236 TDLAVVEKALTYEKFKAWTNSEKLTKSKVQVFLPRLKLEESYDLEPFLRRLGMIDAFDEA 295 T L +E+ LT EK WT E L +V V LPR KLEESY L L RLG+ D F+ + Sbjct: 241 TGLKKIEEQLTLEKLHEWTKPENLDFIEVNVSLPRFKLEESYTLNSDLARLGVQDLFNSS 300 Query: 296 KADFSGMSTEKNVPLSKVAHKCFVEVNEEGTEAAAATAVVRNSRCSRMEPRFCADHPFLF 355 KAD SGMS +++ +SK+ HK FVEVNEEGTEAAAATA + E F ADHPFLF Sbjct: 301 KADLSGMSGARDIFISKIVHKSFVEVNEEGTEAAAATAGIATFCMLMPEENFTADHPFLF 360 Query: 356 FIRHHKTNCILFCGRFSSP 374 FIRH+ + ILF GRFSSP Sbjct: 361 FIRHNSSGSILFLGRFSSP 379 >gi|219689110 serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 2 [Homo sapiens] Length = 415 Score = 337 bits (865), Expect = 8e-93 Identities = 180/416 (43%), Positives = 254/416 (61%), Gaps = 43/416 (10%) Query: 1 MDDLCEANGTFAISLFKILGEEDNSRNVFFSPMSISSALAMVFMGAKGSTAAQMSQALCL 60 M+DLC AN FA++LFK L + ++N+F SP SISS +AMV+MG++GST QM++ L Sbjct: 1 MEDLCVANTLFALNLFKHLAKASPTQNLFLSPWSISSTMAMVYMGSRGSTEDQMAKVLQF 60 Query: 61 YKDG-------------------------------------DIHRGFQSLLSEVNRTGTQ 83 + G IH F+SL S +N + Sbjct: 61 NEVGANAVTPMTPENFTSCGFMQQIQKGSYPDAILQAQAADKIHSSFRSLSSAINASTGN 120 Query: 84 YLLRTANRLFGEKTCDFLPDFKEYCQKFYQAELEELSFAEDTEECRKHINDWVAEKTEGK 143 YLL + N+LFGEK+ F ++ CQK+Y +E + + F E EE RK IN WV +T+GK Sbjct: 121 YLLESVNKLFGEKSASFREEYIRLCQKYYSSEPQAVDFLECAEEARKKINSWVKTQTKGK 180 Query: 144 ISEVLDAGTVDPLTKLVLVNAIYFKGKWNEQFDRKYTRGMLFKTNEEKKT-VQMMFKEAK 202 I +L G+VD T++VLVNA+YFKGKW F++K F+ N ++T VQMM+ K Sbjct: 181 IPNLLPEGSVDGDTRMVLVNAVYFKGKWKTPFEKKLNGLYPFRVNSAQRTPVQMMYLREK 240 Query: 203 FKMGYADEVHTQVLELPYVEEELSMVILLPDD----NTDLAVVEKALTYEKFKAWTNSEK 258 +GY +++ Q+LELPY + +SM +LLPD+ +T L ++E +TY+K WT+ +K Sbjct: 241 LNIGYIEDLKAQILELPYAGD-VSMFLLLPDEIADVSTGLELLESEITYDKLNKWTSKDK 299 Query: 259 LTKSKVQVFLPRLKLEESYDLEPFLRRLGMIDAFDEAKADFSGMSTEKNVPLSKVAHKCF 318 + + +V+V++P+ KLEE Y+L LR +GM DAF++ +A+FSGMS ++ LS+V H+ Sbjct: 300 MAEDEVEVYIPQFKLEEHYELRSILRSMGMEDAFNKGRANFSGMSERNDLFLSEVFHQAM 359 Query: 319 VEVNEEGTEAAAATAVVRNSRCSRMEPRFCADHPFLFFIRHHKTNCILFCGRFSSP 374 V+VNEEGTEAAA T V R P+F ADHPFLF I H TNCILF GRFSSP Sbjct: 360 VDVNEEGTEAAAGTGGVMTGRTGHGGPQFVADHPFLFLIMHKITNCILFFGRFSSP 415 >gi|4505595 serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 2 [Homo sapiens] Length = 415 Score = 337 bits (865), Expect = 8e-93 Identities = 180/416 (43%), Positives = 254/416 (61%), Gaps = 43/416 (10%) Query: 1 MDDLCEANGTFAISLFKILGEEDNSRNVFFSPMSISSALAMVFMGAKGSTAAQMSQALCL 60 M+DLC AN FA++LFK L + ++N+F SP SISS +AMV+MG++GST QM++ L Sbjct: 1 MEDLCVANTLFALNLFKHLAKASPTQNLFLSPWSISSTMAMVYMGSRGSTEDQMAKVLQF 60 Query: 61 YKDG-------------------------------------DIHRGFQSLLSEVNRTGTQ 83 + G IH F+SL S +N + Sbjct: 61 NEVGANAVTPMTPENFTSCGFMQQIQKGSYPDAILQAQAADKIHSSFRSLSSAINASTGN 120 Query: 84 YLLRTANRLFGEKTCDFLPDFKEYCQKFYQAELEELSFAEDTEECRKHINDWVAEKTEGK 143 YLL + N+LFGEK+ F ++ CQK+Y +E + + F E EE RK IN WV +T+GK Sbjct: 121 YLLESVNKLFGEKSASFREEYIRLCQKYYSSEPQAVDFLECAEEARKKINSWVKTQTKGK 180 Query: 144 ISEVLDAGTVDPLTKLVLVNAIYFKGKWNEQFDRKYTRGMLFKTNEEKKT-VQMMFKEAK 202 I +L G+VD T++VLVNA+YFKGKW F++K F+ N ++T VQMM+ K Sbjct: 181 IPNLLPEGSVDGDTRMVLVNAVYFKGKWKTPFEKKLNGLYPFRVNSAQRTPVQMMYLREK 240 Query: 203 FKMGYADEVHTQVLELPYVEEELSMVILLPDD----NTDLAVVEKALTYEKFKAWTNSEK 258 +GY +++ Q+LELPY + +SM +LLPD+ +T L ++E +TY+K WT+ +K Sbjct: 241 LNIGYIEDLKAQILELPYAGD-VSMFLLLPDEIADVSTGLELLESEITYDKLNKWTSKDK 299 Query: 259 LTKSKVQVFLPRLKLEESYDLEPFLRRLGMIDAFDEAKADFSGMSTEKNVPLSKVAHKCF 318 + + +V+V++P+ KLEE Y+L LR +GM DAF++ +A+FSGMS ++ LS+V H+ Sbjct: 300 MAEDEVEVYIPQFKLEEHYELRSILRSMGMEDAFNKGRANFSGMSERNDLFLSEVFHQAM 359 Query: 319 VEVNEEGTEAAAATAVVRNSRCSRMEPRFCADHPFLFFIRHHKTNCILFCGRFSSP 374 V+VNEEGTEAAA T V R P+F ADHPFLF I H TNCILF GRFSSP Sbjct: 360 VDVNEEGTEAAAGTGGVMTGRTGHGGPQFVADHPFLFLIMHKITNCILFFGRFSSP 415 >gi|4826902 serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 10 [Homo sapiens] Length = 397 Score = 318 bits (814), Expect = 6e-87 Identities = 174/397 (43%), Positives = 246/397 (61%), Gaps = 23/397 (5%) Query: 1 MDDLCEANGTFAISLFKILGEEDNSRNVFFSPMSISSALAMVFMGAKGSTAAQMSQALCL 60 MD L + FA+ L K L E +N+FFS SIS++L +V++GAKG+TAAQM+Q L Sbjct: 1 MDSLATSINQFALELSKKLAESAQGKNIFFSSWSISTSLTIVYLGAKGTTAAQMAQVLQF 60 Query: 61 YKDG----------------------DIHRGFQSLLSEVNRTGTQYLLRTANRLFGEKTC 98 +D +IH FQ+L+SE+ + YLL+TAN ++GEKT Sbjct: 61 NRDQGVKCDPESEKKRKMEFNLSNSEEIHSDFQTLISEILKPNDDYLLKTANAIYGEKTY 120 Query: 99 DFLPDFKEYCQKFYQAELEELSFAEDTEECRKHINDWVAEKTEGKISEVLDAGTVDPLTK 158 F + E + ++ AE + ++F E +++ RK IN WV +TEGKI +L +VD T+ Sbjct: 121 AFHNKYLEDMKTYFGAEPQPVNFVEASDQIRKDINSWVERQTEGKIQNLLPDDSVDSTTR 180 Query: 159 LVLVNAIYFKGKWNEQFDRKYTRGMLFKTNEE-KKTVQMMFKEAKFKMGYADEVHTQVLE 217 ++LVNA+YFKG W QF + T F+ NE K VQMMF + K + + ++ L+ Sbjct: 181 MILVNALYFKGIWEHQFLVQNTTEKPFRINETTSKPVQMMFMKKKLHIFHIEKPKAVGLQ 240 Query: 218 LPYVEEELSMVILLPDDNTDLAVVEKALTYEKFKAWTNSEKLTKSKVQVFLPRLKLEESY 277 L Y +LS++ILLP+D L +EKA+TYEK WT+++ + +VQ+ LP+ KLE+SY Sbjct: 241 LYYKSRDLSLLILLPEDINGLEQLEKAITYEKLNEWTSADMMELYEVQLHLPKFKLEDSY 300 Query: 278 DLEPFLRRLGMIDAFDEAKADFSGMSTEKNVPLSKVAHKCFVEVNEEGTEAAAATAVVRN 337 DL+ L +GM DAF ++KADFSGMS+ +N+ LS V HK FVE+NE+GTEAAA + + Sbjct: 301 DLKSTLSSMGMSDAFSQSKADFSGMSSARNLFLSNVFHKAFVEINEQGTEAAAGSGSEID 360 Query: 338 SRCSRMEPRFCADHPFLFFIRHHKTNCILFCGRFSSP 374 R F A+HPFLFFIRH+KTN ILF GR SP Sbjct: 361 IRIRVPSIEFNANHPFLFFIRHNKTNTILFYGRLCSP 397 >gi|28076869 serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 4 [Homo sapiens] Length = 390 Score = 311 bits (798), Expect = 5e-85 Identities = 175/392 (44%), Positives = 240/392 (61%), Gaps = 20/392 (5%) Query: 1 MDDLCEANGTFAISLFKILGEEDNSRNVFFSPMSISSALAMVFMGAKGSTAAQMSQALC- 59 M+ L EAN F LF+ + N+F+SP+SI+SAL MV +GAK +TA Q+S+ L Sbjct: 1 MNSLSEANTKFMFDLFQQF-RKSKENNIFYSPISITSALGMVLLGAKDNTAQQISKVLHF 59 Query: 60 ---------------LYKDGDIHRGFQSLLSEVNRTGTQYLLRTANRLFGEKTCDFLPDF 104 + + G++H FQ LL+E N++ Y L+ AN+LFGEKT FL ++ Sbjct: 60 DQVTENTTEKAATYHVDRSGNVHHQFQKLLTEFNKSTDAYELKIANKLFGEKTYQFLQEY 119 Query: 105 KEYCQKFYQAELEELSFAEDTEECRKHINDWVAEKTEGKISEVLDAGTVDPLTKLVLVNA 164 + +KFYQ +E FA EE RK IN WV +T KI + GT+ T LVLVNA Sbjct: 120 LDAIKKFYQTSVESTDFANAPEESRKKINSWVESQTNEKIKNLFPDGTIGNDTTLVLVNA 179 Query: 165 IYFKGKWNEQFDRKYTRGMLFKTNEEK-KTVQMMFKEAKFKMGYADEVHTQVLELPYVEE 223 IYFKG+W +F ++ T+ F N+ K+VQMM + F ++V +VLE+PY + Sbjct: 180 IYFKGQWENKFKKENTKEEKFWPNKNTYKSVQMMRQYNSFNFALLEDVQAKVLEIPYKGK 239 Query: 224 ELSMVILLPDDNTDLAVVEKALTYEKFKAWTNSEKLTKSKVQVFLPRLKLEESYDLEPFL 283 +LSM++LLP++ L +E+ LT EK WT+ + + ++ V + LPR K+EESYDL+ L Sbjct: 240 DLSMIVLLPNEIDGLQKLEEKLTAEKLMEWTSLQNMRETCVDLHLPRFKMEESYDLKDTL 299 Query: 284 RRLGMIDAFDEAKADFSGMSTEKNVPLSKVAHKCFVEVNEEGTEAAAATAVVRNSRCS-R 342 R +GM++ F+ AD SGM+ + +SKV HK FVEV EEG EAAAATAVV S Sbjct: 300 RTMGMVNIFN-GDADLSGMTWSHGLSVSKVLHKAFVEVTEEGVEAAAATAVVVVELSSPS 358 Query: 343 MEPRFCADHPFLFFIRHHKTNCILFCGRFSSP 374 FC +HPFLFFIR +KTN ILF GRFSSP Sbjct: 359 TNEEFCCNHPFLFFIRQNKTNSILFYGRFSSP 390 >gi|5902072 serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 3 [Homo sapiens] Length = 390 Score = 309 bits (792), Expect = 2e-84 Identities = 172/392 (43%), Positives = 243/392 (61%), Gaps = 20/392 (5%) Query: 1 MDDLCEANGTFAISLFKILGEEDNSRNVFFSPMSISSALAMVFMGAKGSTAAQMSQALC- 59 M+ L EAN F LF+ + N+F+SP+SI+SAL MV +GAK +TA Q+ + L Sbjct: 1 MNSLSEANTKFMFDLFQQF-RKSKENNIFYSPISITSALGMVLLGAKDNTAQQIKKVLHF 59 Query: 60 ---------------LYKDGDIHRGFQSLLSEVNRTGTQYLLRTANRLFGEKTCDFLPDF 104 + + G++H FQ LL+E N++ Y L+ AN+LFGEKT FL ++ Sbjct: 60 DQVTENTTGKAATYHVDRSGNVHHQFQKLLTEFNKSTDAYELKIANKLFGEKTYLFLQEY 119 Query: 105 KEYCQKFYQAELEELSFAEDTEECRKHINDWVAEKTEGKISEVLDAGTVDPLTKLVLVNA 164 + +KFYQ +E + FA EE RK IN WV +T KI ++ G + T LVLVNA Sbjct: 120 LDAIKKFYQTSVESVDFANAPEESRKKINSWVESQTNEKIKNLIPEGNIGSNTTLVLVNA 179 Query: 165 IYFKGKWNEQFDRKYTRGMLFKTNEEK-KTVQMMFKEAKFKMGYADEVHTQVLELPYVEE 223 IYFKG+W ++F+++ T+ F N+ K++QMM + F ++V +VLE+PY + Sbjct: 180 IYFKGQWEKKFNKEDTKEEKFWPNKNTYKSIQMMRQYTSFHFASLEDVQAKVLEIPYKGK 239 Query: 224 ELSMVILLPDDNTDLAVVEKALTYEKFKAWTNSEKLTKSKVQVFLPRLKLEESYDLEPFL 283 +LSM++LLP++ L +E+ LT EK WT+ + + +++V + LPR K+EESYDL+ L Sbjct: 240 DLSMIVLLPNEIDGLQKLEEKLTAEKLMEWTSLQNMRETRVDLHLPRFKVEESYDLKDTL 299 Query: 284 RRLGMIDAFDEAKADFSGMSTEKNVPLSKVAHKCFVEVNEEGTEAAAATAVVR-NSRCSR 342 R +GM+D F+ AD SGM+ + + LS V HK FVEV EEG EAAAATAVV S + Sbjct: 300 RTMGMVDIFN-GDADLSGMTGSRGLVLSGVLHKAFVEVTEEGAEAAAATAVVGFGSSPTS 358 Query: 343 MEPRFCADHPFLFFIRHHKTNCILFCGRFSSP 374 F +HPFLFFIR +KTN ILF GRFSSP Sbjct: 359 TNEEFHCNHPFLFFIRQNKTNSILFYGRFSSP 390 >gi|156071456 serpin peptidase inhibitor, clade B, member 11 [Homo sapiens] Length = 392 Score = 303 bits (777), Expect = 1e-82 Identities = 168/392 (42%), Positives = 231/392 (58%), Gaps = 18/392 (4%) Query: 1 MDDLCEANGTFAISLFKILGEEDNSRNVFFSPMSISSALAMVFMGAKGSTAAQMSQALCL 60 M L AN F + +FK L + N+FFS +S+ AL+MV +GA+G T Q+ + L Sbjct: 1 MGSLSTANVEFCLDVFKELNSNNIGDNIFFSSLSLLYALSMVLLGARGETEEQLEKVLHF 60 Query: 61 ----------YKD-------GDIHRGFQSLLSEVNRTGTQYLLRTANRLFGEKTCDFLPD 103 +KD G IH F S++N+ + L ANRL+G KT F Sbjct: 61 SHTVDSLKPGFKDSPKCSQAGRIHSEFGVEFSQINQPDSNCTLSIANRLYGTKTMAFHQQ 120 Query: 104 FKEYCQKFYQAELEELSFAEDTEECRKHINDWVAEKTEGKISEVLDAGTVDPLTKLVLVN 163 + +K+YQA L+ + F + TEE RK IN WV KT GK++ + T+DP + +VLVN Sbjct: 121 YLSCSEKWYQARLQTVDFEQSTEETRKTINAWVENKTNGKVANLFGKSTIDPSSVMVLVN 180 Query: 164 AIYFKGKWNEQFDRKYTRGMLFKTNEEKK-TVQMMFKEAKFKMGYADEVHTQVLELPYVE 222 AIYFKG+W +F + T F+ +E K TV+MM++ FK+ + E QVLELPYV Sbjct: 181 AIYFKGQWQNKFQVRETVKSPFQLSEGKNVTVEMMYQIGTFKLAFVKEPQMQVLELPYVN 240 Query: 223 EELSMVILLPDDNTDLAVVEKALTYEKFKAWTNSEKLTKSKVQVFLPRLKLEESYDLEPF 282 +LSM+ILLP +L +EK L F WT+S + + +V+V LPR KLE Y+L Sbjct: 241 NKLSMIILLPVGIANLKQIEKQLNSGTFHEWTSSSNMMEREVEVHLPRFKLETKYELNSL 300 Query: 283 LRRLGMIDAFDEAKADFSGMSTEKNVPLSKVAHKCFVEVNEEGTEAAAATAVVRNSRCSR 342 L+ LG+ D F++ KAD SGMS K + LSK HK +++V+EEGTEAAAAT + Sbjct: 301 LKSLGVTDLFNQVKADLSGMSPTKGLYLSKAIHKSYLDVSEEGTEAAAATGDSIAVKSLP 360 Query: 343 MEPRFCADHPFLFFIRHHKTNCILFCGRFSSP 374 M +F A+HPFLFFIRH TN ILFCG+ +SP Sbjct: 361 MRAQFKANHPFLFFIRHTHTNTILFCGKLASP 392 >gi|17998551 serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 12 [Homo sapiens] Length = 405 Score = 295 bits (756), Expect = 3e-80 Identities = 164/405 (40%), Positives = 241/405 (59%), Gaps = 31/405 (7%) Query: 1 MDDLCEANGTFAISLFKILGEEDNSRNVFFSPMSISSALAMVFMGAKGSTAAQMSQAL-- 58 MD L AN F LF+ +G++D +N+FFSP+S+S+AL MV +GA+ +A Q+ + L Sbjct: 1 MDSLVTANTKFCFDLFQEIGKDDRHKNIFFSPLSLSAALGMVRLGARSDSAHQIDEVLHF 60 Query: 59 -------------CL----YKDGDIHRG-------FQSLLSEVNRTGTQYLLRTANRLFG 94 CL K G ++ F LLS+++R T Y L ANRL+G Sbjct: 61 NEFSQNESKEPDPCLKSNKQKAGSLNNESGLVSCYFGQLLSKLDRIKTDYTLSIANRLYG 120 Query: 95 EKTCDFLPDFKEYCQKFYQAELEELSFAEDTEECRKHINDWVAEKTEGKISEVLDAGTVD 154 E+ ++ + +FY +E + F ++ E+ R+ IN WV +++GKI E+ ++ Sbjct: 121 EQEFPICQEYLDGVIQFYHTTIESVDFQKNPEKSRQEINFWVECQSQGKIKELFSKDAIN 180 Query: 155 PLTKLVLVNAIYFKGKWNEQFDRKYTRGMLFKTN-EEKKTVQMMFKEAKFKMGYADEVHT 213 T LVLVNA+YFK KW FD + T F N E K+V+MM ++ +++G+ +EV Sbjct: 181 AETVLVLVNAVYFKAKWETYFDHENTVDAPFCLNANENKSVKMMTQKGLYRIGFIEEVKA 240 Query: 214 QVLELPYVEEELSMVILLPDDNTD----LAVVEKALTYEKFKAWTNSEKLTKSKVQVFLP 269 Q+LE+ Y + +LSM +LLP + D L +E+ +TYEK AW++SE +++ V + P Sbjct: 241 QILEMRYTKGKLSMFVLLPSHSKDNLKGLEELERKITYEKMVAWSSSENMSEESVVLSFP 300 Query: 270 RLKLEESYDLEPFLRRLGMIDAFDEAKADFSGMSTEKNVPLSKVAHKCFVEVNEEGTEAA 329 R LE+SYDL L+ +G+ D FDE +AD +G+S N+ LSK+ HK FVEV+E GT+AA Sbjct: 301 RFTLEDSYDLNSILQDMGITDIFDETRADLTGISPSPNLYLSKIIHKTFVEVDENGTQAA 360 Query: 330 AATAVVRNSRCSRMEPRFCADHPFLFFIRHHKTNCILFCGRFSSP 374 AAT V + R R F A+HPFLFFIRH+KT ILF GR SP Sbjct: 361 AATGAVVSERSLRSWVEFNANHPFLFFIRHNKTQTILFYGRVCSP 405 >gi|8393956 serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 13 [Homo sapiens] Length = 391 Score = 284 bits (727), Expect = 8e-77 Identities = 154/392 (39%), Positives = 224/392 (57%), Gaps = 19/392 (4%) Query: 1 MDDLCEANGTFAISLFKILGEEDNSRNVFFSPMSISSALAMVFMGAKGSTAAQMSQALCL 60 MD L + LFK L ++ N N+FFSP+ I +A+ MV +G +G+TA+Q+ + Sbjct: 1 MDSLGAVSTRLGFDLFKEL-KKTNDGNIFFSPVGILTAIGMVLLGTRGATASQLEEVFHS 59 Query: 61 YKDGD-----------------IHRGFQSLLSEVNRTGTQYLLRTANRLFGEKTCDFLPD 103 K+ +H+ FQ L+E+++ Y L NRLFGEKT FL Sbjct: 60 EKETKSSRIKAEEKEVIENTEAVHQQFQKFLTEISKLTNDYELNITNRLFGEKTYLFLQK 119 Query: 104 FKEYCQKFYQAELEELSFAEDTEECRKHINDWVAEKTEGKISEVLDAGTVDPLTKLVLVN 163 + +Y +K+Y A LE + F +E RK IN WV KT KI ++ G++ TKLVLVN Sbjct: 120 YLDYVEKYYHASLEPVDFVNAADESRKKINSWVESKTNEKIKDLFPDGSISSSTKLVLVN 179 Query: 164 AIYFKGKWNEQFDRKYTRGMLFKTNEE-KKTVQMMFKEAKFKMGYADEVHTQVLELPYVE 222 +YFKG+W+ +F ++ T+ F N+ K+VQMM + F + +++ ++L +PY Sbjct: 180 MVYFKGQWDREFKKENTKEEKFWMNKSTSKSVQMMTQSHSFSFTFLEDLQAKILGIPYKN 239 Query: 223 EELSMVILLPDDNTDLAVVEKALTYEKFKAWTNSEKLTKSKVQVFLPRLKLEESYDLEPF 282 +LSM +LLP+D L + ++ EK WT+ + + KV + LPR ++E+ YDLE Sbjct: 240 NDLSMFVLLPNDIDGLEKIIDKISPEKLVEWTSPGHMEERKVNLHLPRFEVEDGYDLEAV 299 Query: 283 LRRLGMIDAFDEAKADFSGMSTEKNVPLSKVAHKCFVEVNEEGTEAAAATAVVRNSRCSR 342 L +GM DAF E KAD+SGMS+ + K H FV V EEGTEAAAAT + + Sbjct: 300 LAAMGMGDAFSEHKADYSGMSSGSGLYAQKFLHSSFVAVTEEGTEAAAATGIGFTVTSAP 359 Query: 343 MEPRFCADHPFLFFIRHHKTNCILFCGRFSSP 374 +HPFLFFIRH+++N ILF GRFSSP Sbjct: 360 GHENVHCNHPFLFFIRHNESNSILFFGRFSSP 391 >gi|167860126 serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 5 [Homo sapiens] Length = 375 Score = 258 bits (659), Expect = 6e-69 Identities = 143/379 (37%), Positives = 222/379 (58%), Gaps = 9/379 (2%) Query: 1 MDDLCEANGTFAISLFKILGEEDNSRNVFFSPMSISSALAMVFMGAKGSTAAQMSQALCL 60 MD L AN FA+ LFK L E++ NV FSP+ +S++L++ +GAKG TA ++ Q L Sbjct: 1 MDALQLANSAFAVDLFKQLCEKEPLGNVLFSPICLSTSLSLAQVGAKGDTANEIGQVLHF 60 Query: 61 YKDGDIHRGFQSLLSEVNRTGTQYLLRTANRLFGEKTCDFLPDFKEYCQKFYQAELEELS 120 D+ GFQ++ S+VN+ + Y L+ RL+ +K+ + +F ++ Y ELE + Sbjct: 61 ENVKDVPFGFQTVTSDVNKLSSFYSLKLIKRLYVDKSLNLSTEFISSTKRPYAKELETVD 120 Query: 121 FAEDTEECRKHINDWVAEKTEGKISEVLDAGTVDPLTKLVLVNAIYFKGKWNEQFDRKYT 180 F + EE + IN+ + + T+G +L +V+ TK+++VNA YF GKW ++F T Sbjct: 121 FKDKLEETKGQINNSIKDLTDGHFENILADNSVNDQTKILVVNAAYFVGKWMKKFSESET 180 Query: 181 RGMLFKTNE-EKKTVQMMFKEAKFKMGYADEVHTQVLELPYVEEELSMVILLP----DDN 235 + F+ N+ + K VQMM EA F MG D ++ +++ELP+ + LSM ILLP D++ Sbjct: 181 KECPFRVNKTDTKPVQMMNMEATFCMGNIDSINCKIIELPFQNKHLSMFILLPKDVEDES 240 Query: 236 TDLAVVEKALTYEKFKAWTNSEKLTKSKVQVFLPRLKLEESYDLEPFLRRLGMIDAFDEA 295 T L +EK L E WTN + +KV++ +P+ K+E+ D + L LG+ F E Sbjct: 241 TGLEKIEKQLNSESLSQWTNPSTMANAKVKLSIPKFKVEKMIDPKACLENLGLKHIFSED 300 Query: 296 KADFSGMSTEKNVPLSKVAHKCFVEVNEEGTEAAAATAVVRNSRCSRMEPRFCADHPFLF 355 +DFSGMS K V LS V HK +E+ E+G ++ V +R + + ADHPF++ Sbjct: 301 TSDFSGMSETKGVALSNVIHKVCLEITEDGGDSIE----VPGARILQHKDELNADHPFIY 356 Query: 356 FIRHHKTNCILFCGRFSSP 374 IRH+KT I+F G+F SP Sbjct: 357 IIRHNKTRNIIFFGKFCSP 375 >gi|92859634 serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 7 [Homo sapiens] Length = 380 Score = 253 bits (647), Expect = 1e-67 Identities = 144/385 (37%), Positives = 220/385 (57%), Gaps = 16/385 (4%) Query: 1 MDDLCEANGTFAISLFKILGEEDNSRNVFFSPMSISSALAMVFMGAKGSTAAQMSQALCL 60 M L AN F +LF+ + + + NVFFS +S+ +ALA+V +GA+ + +Q+ + L + Sbjct: 1 MASLAAANAEFCFNLFREMDDNQGNGNVFFSSLSLFAALALVRLGAQDDSLSQIDKLLHV 60 Query: 61 Y------KDGDIHRGFQSLL----SEVNRTGTQYLLRTANRLFGEKTCDFLPDFKEYCQK 110 + G QS L S++N + Y L N LF EK F D+ E +K Sbjct: 61 NTASGYGNSSNSQSGLQSQLKRVFSDINASHKDYDLSIVNGLFAEKVYGFHKDYIECAEK 120 Query: 111 FYQAELEELSFAEDTEECRKHINDWVAEKTEGKISEVLDAGTVDPLTKLVLVNAIYFKGK 170 Y A++E + F E+ R++IN WV +T GKI V+ G + +VLVNA+YFKGK Sbjct: 121 LYDAKVERVDFTNHLEDTRRNINKWVENETHGKIKNVIGEGGISSSAVMVLVNAVYFKGK 180 Query: 171 WNEQFDRKYTRGMLFKTNE-EKKTVQMMFKEAKFKMGYADEVHTQVLELPYVEEELSMVI 229 W F + T FK+ + K V MM +E KF + ++ ++LEL Y ++M + Sbjct: 181 WQSAFTKSETINCHFKSPKCSGKAVAMMHQERKFNLSVIEDPSMKILELRY-NGGINMYV 239 Query: 230 LLPDDNTDLAVVEKALTYEKFKAWTNSEKLTKSKVQVFLPRLKLEESYDLEPFLRRLGMI 289 LLP++ DL+ +E LT++ WTN ++T V+VF P+ K+E++Y+++ +LR LG+ Sbjct: 240 LLPEN--DLSEIENKLTFQNLMEWTNPRRMTSKYVEVFFPQFKIEKNYEMKQYLRALGLK 297 Query: 290 DAFDEAKADFSGMSTEKNVPLSKVAHKCFVEVNEEGTEAAAATAVVRNSRCSRMEPRFCA 349 D FDE+KAD SG+++ + +S++ HK ++EV EEGTEA AAT + F A Sbjct: 298 DIFDESKADLSGIASGGRLYISRMMHKSYIEVTEEGTEATAATGSNIVEKQLPQSTLFRA 357 Query: 350 DHPFLFFIRHHKTNCILFCGRFSSP 374 DHPFLF IR K + ILF G+ S P Sbjct: 358 DHPFLFVIR--KDDIILFSGKVSCP 380 >gi|4505149 serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 7 [Homo sapiens] Length = 380 Score = 253 bits (647), Expect = 1e-67 Identities = 144/385 (37%), Positives = 220/385 (57%), Gaps = 16/385 (4%) Query: 1 MDDLCEANGTFAISLFKILGEEDNSRNVFFSPMSISSALAMVFMGAKGSTAAQMSQALCL 60 M L AN F +LF+ + + + NVFFS +S+ +ALA+V +GA+ + +Q+ + L + Sbjct: 1 MASLAAANAEFCFNLFREMDDNQGNGNVFFSSLSLFAALALVRLGAQDDSLSQIDKLLHV 60 Query: 61 Y------KDGDIHRGFQSLL----SEVNRTGTQYLLRTANRLFGEKTCDFLPDFKEYCQK 110 + G QS L S++N + Y L N LF EK F D+ E +K Sbjct: 61 NTASGYGNSSNSQSGLQSQLKRVFSDINASHKDYDLSIVNGLFAEKVYGFHKDYIECAEK 120 Query: 111 FYQAELEELSFAEDTEECRKHINDWVAEKTEGKISEVLDAGTVDPLTKLVLVNAIYFKGK 170 Y A++E + F E+ R++IN WV +T GKI V+ G + +VLVNA+YFKGK Sbjct: 121 LYDAKVERVDFTNHLEDTRRNINKWVENETHGKIKNVIGEGGISSSAVMVLVNAVYFKGK 180 Query: 171 WNEQFDRKYTRGMLFKTNE-EKKTVQMMFKEAKFKMGYADEVHTQVLELPYVEEELSMVI 229 W F + T FK+ + K V MM +E KF + ++ ++LEL Y ++M + Sbjct: 181 WQSAFTKSETINCHFKSPKCSGKAVAMMHQERKFNLSVIEDPSMKILELRY-NGGINMYV 239 Query: 230 LLPDDNTDLAVVEKALTYEKFKAWTNSEKLTKSKVQVFLPRLKLEESYDLEPFLRRLGMI 289 LLP++ DL+ +E LT++ WTN ++T V+VF P+ K+E++Y+++ +LR LG+ Sbjct: 240 LLPEN--DLSEIENKLTFQNLMEWTNPRRMTSKYVEVFFPQFKIEKNYEMKQYLRALGLK 297 Query: 290 DAFDEAKADFSGMSTEKNVPLSKVAHKCFVEVNEEGTEAAAATAVVRNSRCSRMEPRFCA 349 D FDE+KAD SG+++ + +S++ HK ++EV EEGTEA AAT + F A Sbjct: 298 DIFDESKADLSGIASGGRLYISRMMHKSYIEVTEEGTEATAATGSNIVEKQLPQSTLFRA 357 Query: 350 DHPFLFFIRHHKTNCILFCGRFSSP 374 DHPFLF IR K + ILF G+ S P Sbjct: 358 DHPFLFVIR--KDDIILFSGKVSCP 380 >gi|4502261 serpin peptidase inhibitor, clade C, member 1 [Homo sapiens] Length = 464 Score = 234 bits (598), Expect = 7e-62 Identities = 147/383 (38%), Positives = 222/383 (57%), Gaps = 14/383 (3%) Query: 3 DLCEANGTFAISLFKILGEEDNSR-NVFFSPMSISSALAMVFMGAKGSTAAQMSQALCL- 60 +L +AN FA + ++ L + N N+F SP+SIS+A AM +GA T Q+ + Sbjct: 82 ELSKANSRFATTFYQHLADSKNDNDNIFLSPLSISTAFAMTKLGACNDTLQQLMEVFKFD 141 Query: 61 ---YKDGD-IHRGFQSLLSEVNRTGTQYL-LRTANRLFGEKTCDFLPDFKEYCQKFYQAE 115 K D IH F L + R + L +ANRLFG+K+ F +++ + Y A+ Sbjct: 142 TISEKTSDQIHFFFAKLNCRLYRKANKSSKLVSANRLFGDKSLTFNETYQDISELVYGAK 201 Query: 116 LEELSFAEDTEECRKHINDWVAEKTEGKISEVLDAGTVDPLTKLVLVNAIYFKGKWNEQF 175 L+ L F E+ E+ R IN WV+ KTEG+I++V+ + ++ LT LVLVN IYFKG W +F Sbjct: 202 LQPLDFKENAEQSRAAINKWVSNKTEGRITDVIPSEAINELTVLVLVNTIYFKGLWKSKF 261 Query: 176 DRKYTRGMLF-KTNEEKKTVQMMFKEAKFKMGYADEVHTQVLELPYVEEELSMVILLPDD 234 + TR LF K + E + MM++E KF+ E TQVLELP+ ++++MV++LP Sbjct: 262 SPENTRKELFYKADGESCSASMMYQEGKFRYRRVAE-GTQVLELPFKGDDITMVLILPKP 320 Query: 235 NTDLAVVEKALTYEKFKAWTNSEKLTKSKVQVFLPRLKLEESYDLEPFLRRLGMIDAFDE 294 LA VEK LT E + W ++L + + V +PR ++E+ + L+ L+ +G++D F Sbjct: 321 EKSLAKVEKELTPEVLQEWL--DELEEMMLVVHMPRFRIEDGFSLKEQLQDMGLVDLFSP 378 Query: 295 AKADFSGMSTE--KNVPLSKVAHKCFVEVNEEGTEAAAATAVVRNSR-CSRMEPRFCADH 351 K+ G+ E ++ +S HK F+EVNEEG+EAAA+TAVV R + F A+ Sbjct: 379 EKSKLPGIVAEGRDDLYVSDAFHKAFLEVNEEGSEAAASTAVVIAGRSLNPNRVTFKANR 438 Query: 352 PFLFFIRHHKTNCILFCGRFSSP 374 PFL FIR N I+F GR ++P Sbjct: 439 PFLVFIREVPLNTIIFMGRVANP 461 >gi|170295807 neuroserpin precursor [Homo sapiens] Length = 410 Score = 218 bits (555), Expect = 7e-57 Identities = 125/378 (33%), Positives = 211/378 (55%), Gaps = 13/378 (3%) Query: 6 EANGTFAISLFKILGEEDNSRNVFFSPMSISSALAMVFMGAKGSTAAQMSQALCL--YKD 63 EA +++++ L N+ FSP+SI+ A+ M+ +GA+GST ++ ++ K+ Sbjct: 24 EAIADLSVNMYNRLRATGEDENILFSPLSIALAMGMMELGAQGSTQKEIRHSMGYDSLKN 83 Query: 64 GDIHRGFQSLLSEVNRTGTQYLLRTANRLFGEKTCDFLPDFKEYCQKFYQAELEELSFAE 123 G+ + + V +QY+++ AN LF + +F + +K++ A + + F++ Sbjct: 84 GEEFSFLKEFSNMVTAKESQYVMKIANSLFVQNGFHVNEEFLQMMKKYFNAAVNHVDFSQ 143 Query: 124 DTEECRKHINDWVAEKTEGKISEVLDAGTVDPLTKLVLVNAIYFKGKWNEQFDRKYTRGM 183 + +IN WV T + +++ D T L L+NA+YFKG W QF + TR Sbjct: 144 NVAVAN-YINKWVENNTNNLVKDLVSPRDFDAATYLALINAVYFKGNWKSQFRPENTRTF 202 Query: 184 LF-KTNEEKKTVQMMFKEAKFKMG-YADEVHT-----QVLELPYVEEELSMVILLPDDNT 236 F K +E + + MM+++ +F G ++D + QVLE+PY +E+SM+++L Sbjct: 203 SFTKDDESEVQIPMMYQQGEFYYGEFSDGSNEAGGIYQVLEIPYEGDEISMMLVLSRQEV 262 Query: 237 DLAVVEKALTYEKFKAWTNSEKLTKSKVQVFLPRLKLEESYDLEPFLRRLGMIDAFDEAK 296 LA +E + + + W NS K K KV+V+LPR +E+ DL+ L+ LG+ + F + Sbjct: 263 PLATLEPLVKAQLVEEWANSVK--KQKVEVYLPRFTVEQEIDLKDVLKALGITEIFIK-D 319 Query: 297 ADFSGMSTEKNVPLSKVAHKCFVEVNEEGTEAAAATAVVRNSRCSRMEPRFCADHPFLFF 356 A+ +G+S K + LSK HK F+EVNEEG+EAAA + ++ SR + + P+ DHPF F Sbjct: 320 ANLTGLSDNKEIFLSKAIHKSFLEVNEEGSEAAAVSGMIAISRMAVLYPQVIVDHPFFFL 379 Query: 357 IRHHKTNCILFCGRFSSP 374 IR+ +T ILF GR P Sbjct: 380 IRNRRTGTILFMGRVMHP 397 >gi|4826904 neuroserpin precursor [Homo sapiens] Length = 410 Score = 218 bits (555), Expect = 7e-57 Identities = 125/378 (33%), Positives = 211/378 (55%), Gaps = 13/378 (3%) Query: 6 EANGTFAISLFKILGEEDNSRNVFFSPMSISSALAMVFMGAKGSTAAQMSQALCL--YKD 63 EA +++++ L N+ FSP+SI+ A+ M+ +GA+GST ++ ++ K+ Sbjct: 24 EAIADLSVNMYNRLRATGEDENILFSPLSIALAMGMMELGAQGSTQKEIRHSMGYDSLKN 83 Query: 64 GDIHRGFQSLLSEVNRTGTQYLLRTANRLFGEKTCDFLPDFKEYCQKFYQAELEELSFAE 123 G+ + + V +QY+++ AN LF + +F + +K++ A + + F++ Sbjct: 84 GEEFSFLKEFSNMVTAKESQYVMKIANSLFVQNGFHVNEEFLQMMKKYFNAAVNHVDFSQ 143 Query: 124 DTEECRKHINDWVAEKTEGKISEVLDAGTVDPLTKLVLVNAIYFKGKWNEQFDRKYTRGM 183 + +IN WV T + +++ D T L L+NA+YFKG W QF + TR Sbjct: 144 NVAVAN-YINKWVENNTNNLVKDLVSPRDFDAATYLALINAVYFKGNWKSQFRPENTRTF 202 Query: 184 LF-KTNEEKKTVQMMFKEAKFKMG-YADEVHT-----QVLELPYVEEELSMVILLPDDNT 236 F K +E + + MM+++ +F G ++D + QVLE+PY +E+SM+++L Sbjct: 203 SFTKDDESEVQIPMMYQQGEFYYGEFSDGSNEAGGIYQVLEIPYEGDEISMMLVLSRQEV 262 Query: 237 DLAVVEKALTYEKFKAWTNSEKLTKSKVQVFLPRLKLEESYDLEPFLRRLGMIDAFDEAK 296 LA +E + + + W NS K K KV+V+LPR +E+ DL+ L+ LG+ + F + Sbjct: 263 PLATLEPLVKAQLVEEWANSVK--KQKVEVYLPRFTVEQEIDLKDVLKALGITEIFIK-D 319 Query: 297 ADFSGMSTEKNVPLSKVAHKCFVEVNEEGTEAAAATAVVRNSRCSRMEPRFCADHPFLFF 356 A+ +G+S K + LSK HK F+EVNEEG+EAAA + ++ SR + + P+ DHPF F Sbjct: 320 ANLTGLSDNKEIFLSKAIHKSFLEVNEEGSEAAAVSGMIAISRMAVLYPQVIVDHPFFFL 379 Query: 357 IRHHKTNCILFCGRFSSP 374 IR+ +T ILF GR P Sbjct: 380 IRNRRTGTILFMGRVMHP 397 >gi|5453886 serpin peptidase inhibitor, clade I (pancpin), member 2 [Homo sapiens] Length = 405 Score = 206 bits (523), Expect = 4e-53 Identities = 123/374 (32%), Positives = 207/374 (55%), Gaps = 10/374 (2%) Query: 6 EANGTFAISLFKILGEEDNSRNVFFSPMSISSALAMVFMGAKGSTAAQMSQALCLYKD-- 63 + N FA+ L++ + N+ FSP+ I+ L MV +GAKG Q+ Q L + Sbjct: 24 QKNTEFAVDLYQEVSLSHKD-NIIFSPLGITLVLEMVQLGAKGKAQQQIRQTLKQQETSA 82 Query: 64 GDIHRGFQSLLSEVNRTGTQYLLRTANRLFGEKTCDFLPDFKEYCQKFYQAELEELSFAE 123 G+ +S S ++ ++ AN L+ ++ + ++F+Q+ ++ + F + Sbjct: 83 GEEFFVLKSFFSAISEKKQEFTFNLANALYLQEGFTVKEQYLHGNKEFFQSAIKLVDF-Q 141 Query: 124 DTEECRKHINDWVAEKTEGKISEVLDAGTVDPLTKLVLVNAIYFKGKWNEQFDRKYTRGM 183 D + C + I+ WV KT+GKI ++ PLT+LVLVNAIYFKG W ++F ++ T+ + Sbjct: 142 DAKACAEMISTWVERKTDGKIKDMFSGEEFGPLTRLVLVNAIYFKGDWKQKFRKEDTQLI 201 Query: 184 LF-KTNEEKKTVQMMFKEAKFKMGYADE--VHTQVLELPYVEEELSMVILLPDDNTDLAV 240 F K N + MM + K GY E ++ QVLEL Y +E S++I+LP + D+ Sbjct: 202 NFTKKNGSTVKIPMMKALLRTKYGYFSESSLNYQVLELSYKGDEFSLIIILPAEGMDIEE 261 Query: 241 VEKALTYEKFKAWTNSEKLTKSKVQVFLPRLKLEESYDLEPFLRRLGMIDAFDEAKADFS 300 VEK +T ++ W + ++ + +V++ LPR K+E+ D + L L + + F D S Sbjct: 262 VEKLITAQQILKWLS--EMQEEEVEISLPRFKVEQKVDFKDVLYSLNITEIFSGG-CDLS 318 Query: 301 GMSTEKNVPLSKVAHKCFVEVNEEGTEAAAATAVVRNSRCSRMEPRFCADHPFLFFIRHH 360 G++ V +S+V K F E+NE+G+EAA +T + S + +F A+HPFLF ++H+ Sbjct: 319 GITDSSEVYVSQVTQKVFFEINEDGSEAATSTGIHIPVIMSLAQSQFIANHPFLFIMKHN 378 Query: 361 KTNCILFCGRFSSP 374 T ILF GR ++P Sbjct: 379 PTESILFMGRVTNP 392 >gi|194018472 serine (or cysteine) proteinase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 [Homo sapiens] Length = 406 Score = 186 bits (473), Expect = 2e-47 Identities = 124/370 (33%), Positives = 199/370 (53%), Gaps = 17/370 (4%) Query: 11 FAISLFKILGEEDNSRNVFFSPMSISSALAMVFMGAKGSTAAQMSQALCLY----KDGDI 66 F L++ L S+++FFSP+SIS +LAM+ +GA ST Q+ + L L + ++ Sbjct: 48 FTFDLYRALASAAPSQSIFFSPVSISMSLAMLSLGAGSSTKMQILEGLGLNLQKSSEKEL 107 Query: 67 HRGFQSLLSEVNRTGTQYLLRTANRLFGEKTCDFLPDFKEYCQKFYQAELEELSFAEDTE 126 HRGFQ LL E+N+ + L N LF + D F + Y A+ +F D+ Sbjct: 108 HRGFQQLLQELNQPRDGFQLSLGNALFTDLVVDLQDTFVSAMKTLYLADTFPTNF-RDSA 166 Query: 127 ECRKHINDWVAEKTEGKISEVLDAGTVDPLTKLVLVNAIYFKGKWNEQFDRKYTRGM-LF 185 K IND+VA++T+GKI ++L +D +++VN I+FK KW F+ K T+ + Sbjct: 167 GAMKQINDYVAKQTKGKIVDLLK--NLDSNAVVIMVNYIFFKAKWETSFNHKGTQEQDFY 224 Query: 186 KTNEEKKTVQMMFKEAKFKMGYADEVHTQVLELPYVEEELSMVILLPDDNTDLAVVEKAL 245 T+E V MM +E ++ + +V+ +PY + + + +LP + + VE L Sbjct: 225 VTSETVVRVPMMSREDQYHYLLDRNLSCRVVGVPY-QGNATALFILPSEGK-MQQVENGL 282 Query: 246 TYEKFKAWTNSEKLTKSKVQVFLPRLKLEESYDLEPFLRRLGMIDAFDEAKADFSGMSTE 305 + + + W K K +++++LP+ +E SY LE L LG+ + F + AD SG+S Sbjct: 283 SEKTLRKWLKMFK--KRQLELYLPKFSIEGSYQLEKVLPSLGISNVFT-SHADLSGISNH 339 Query: 306 KNVPLSKVAHKCFVEVNEEGTEAAAATAVVRNSRCSRM-EPRFCADHPFLFFIRHHKTNC 364 N+ +S++ HK VEV+E GT AAAAT + R +R+ R + PFL FI N Sbjct: 340 SNIQVSEMVHKAVVEVDESGTRAAAATGTIFTFRSARLNSQRLVFNRPFLMFI---VDNN 396 Query: 365 ILFCGRFSSP 374 ILF G+ + P Sbjct: 397 ILFLGKVNRP 406 >gi|110225347 serine (or cysteine) proteinase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 9 isoform A [Homo sapiens] Length = 435 Score = 183 bits (465), Expect = 2e-46 Identities = 124/379 (32%), Positives = 206/379 (54%), Gaps = 24/379 (6%) Query: 8 NGTFAISLFKILGEEDNSRNVFFSPMSISSALAMVFMGAKGSTAAQMSQALCL----YKD 63 N FA L++ L E S+N+FFSP+S+S++LAM+ +GA T Q+ Q L + Sbjct: 66 NTDFAFRLYRRLVLETPSQNIFFSPVSVSTSLAMLSLGAHSVTKTQILQGLGFNLTHTPE 125 Query: 64 GDIHRGFQSLLSEVNRTGTQYLLRTANRLFGEKTCDFLPDFKEYCQKFYQAELEELSFAE 123 IH+GFQ L+ + L+ + LF +K +F ++ Y+AE+ F+ Sbjct: 126 SAIHQGFQHLVHSLTVPSKDLTLKMGSALFVKKELQLQANFLGNVKRLYEAEVFSTDFS- 184 Query: 124 DTEECRKHINDWVAEKTEGKISEVLDAGTVDPLTKLVLVNAIYFKGKWNEQFDRKYTR-G 182 + + IN V +KT+GK+ +++ +D LT +VLVN I+FK KW + F +YTR Sbjct: 185 NPSIAQARINSHVKKKTQGKVVDIIQG--LDLLTAMVLVNHIFFKAKWEKPFHPEYTRKN 242 Query: 183 MLFKTNEEKKT-VQMMFKEAKFKMGYADEVHTQVLELPYVEEELSMVILLPDDNTDLAVV 241 F E+ V MM ++ +F G E++ VL++ Y + ++ +L + + Sbjct: 243 FPFLVGEQVTVHVPMMHQKEQFAFGVDTELNCFVLQMDYKGDAVAFFVL--PSKGKMRQL 300 Query: 242 EKALTYEKFKAWTNSEKLTKSKVQVFLPRLKLEESYDLEPFLRRLGMIDAFDEAKADFSG 301 E+AL+ + W++S L K ++VF+PR + SY+LE L ++G+ + FD+ ADFSG Sbjct: 301 EQALSARTLRKWSHS--LQKRWIEVFIPRFSISASYNLETILPKMGIQNVFDK-NADFSG 357 Query: 302 MSTEKNVPLSKVAHKCFVEVNEEGTEAAAATA---VVRNSRCSRMEPRFCA---DHPFLF 355 ++ ++ +SK HK ++V+EEGTEA AAT +VR S+ P + + FL Sbjct: 358 IAKRDSLQVSKATHKAVLDVSEEGTEATAATTTKFIVR----SKDGPSYFTVSFNRTFLM 413 Query: 356 FIRHHKTNCILFCGRFSSP 374 I + T+ ILF G+ +P Sbjct: 414 MITNKATDGILFLGKVENP 432 >gi|10835159 plasminogen activator inhibitor-1 [Homo sapiens] Length = 402 Score = 182 bits (463), Expect = 3e-46 Identities = 117/370 (31%), Positives = 193/370 (52%), Gaps = 11/370 (2%) Query: 11 FAISLFKILGEEDNSRNVFFSPMSISSALAMVFMGAKGSTAAQMSQALCL-YKDGDIHRG 69 F + +F+ + + RNV FSP ++S LAM+ + G T Q+ A+ D + Sbjct: 38 FGVRVFQQVAQASKDRNVVFSPYGVASVLAMLQLTTGGETQQQIQAAMGFKIDDKGMAPA 97 Query: 70 FQSLLSEVNRTGTQYLLRTANRLFGEKTCDFLPDFKEYCQKFYQAELEELSFAEDTEECR 129 + L E+ + + T + +F ++ + F + + +++ ++++ F+E E R Sbjct: 98 LRHLYKELMGPWNKDEISTTDAIFVQRDLKLVQGFMPHFFRLFRSTVKQVDFSE-VERAR 156 Query: 130 KHINDWVAEKTEGKISEVLDAGTVDPLTKLVLVNAIYFKGKWNEQFDRKYTRGMLF-KTN 188 INDWV T+G IS +L G VD LT+LVLVNA+YF G+W F T LF K++ Sbjct: 157 FIINDWVKTHTKGMISNLLGKGAVDQLTRLVLVNALYFNGQWKTPFPDSSTHRRLFHKSD 216 Query: 189 EEKKTVQMMFKEAKF---KMGYADEVHTQVLELPYVEEELSMVILLP-DDNTDLAVVEKA 244 +V MM + KF + D + +LELPY + LSM I P + L+ + Sbjct: 217 GSTVSVPMMAQTNKFNYTEFTTPDGHYYDILELPYHGDTLSMFIAAPYEKEVPLSALTNI 276 Query: 245 LTYEKFKAWTNSEKLTKSKVQVFLPRLKLEESYDLEPFLRRLGMIDAFDEAKADFSGMST 304 L+ + W + +T+ + LP+ LE DL L LGM D F + +ADF+ +S Sbjct: 277 LSAQLISHWKGN--MTRLPRLLVLPKFSLETEVDLRKPLENLGMTDMFRQFQADFTSLSD 334 Query: 305 EKNVPLSKVAHKCFVEVNEEGTEAAAATAVVRNSRCSRMEPRFCADHPFLFFIRHHKTNC 364 ++ + +++ K +EVNE GT A+++TAV+ ++R + E D PFLF +RH+ T Sbjct: 335 QEPLHVAQALQKVKIEVNESGTVASSSTAVIVSARMAPEE--IIMDRPFLFVVRHNPTGT 392 Query: 365 ILFCGRFSSP 374 +LF G+ P Sbjct: 393 VLFMGQVMEP 402 >gi|73858566 heparin cofactor II precursor [Homo sapiens] Length = 499 Score = 181 bits (460), Expect = 7e-46 Identities = 119/378 (31%), Positives = 202/378 (53%), Gaps = 22/378 (5%) Query: 8 NGTFAISLFKILGEEDNS-RNVFFSPMSISSALAMVFMGAKGSTAAQMSQALCL------ 60 N FA +L+++L ++ N+ N+F +P+ IS+A+ M+ +G KG T Q+ L Sbjct: 130 NAKFAFNLYRVLKDQVNTFDNIFIAPVGISTAMGMISLGLKGETHEQVHSILHFKDFVNA 189 Query: 61 ---YKDGDIHRGFQSLLSEVNRTGTQYLLRTANRLFGEKTCDFLPDFKEYCQKFYQAELE 117 Y+ IH F+ L + R Y LR+ N L+ +K L DFK +++Y AE + Sbjct: 190 SSKYEITTIHNLFRKLTHRLFRRNFGYTLRSVNDLYIQKQFPILLDFKTKVREYYFAEAQ 249 Query: 118 ELSFAEDTEECRKHINDWVAEKTEGKISEVLDAGTVDPLTKLVLVNAIYFKGKWNEQFDR 177 F++ + N+ + + T+G I + L+ +DP T+++++N IYFKG W +F Sbjct: 250 IADFSDPAFISKT--NNHIMKLTKGLIKDALE--NIDPATQMMILNCIYFKGSWVNKFPV 305 Query: 178 KYTRGMLFKTNE-EKKTVQMMFKEAKFKMGYADEVHTQVLELPYVEEELSMVILLPDDNT 236 + T F+ NE E V MM + F E+ +L+L YV +SM+I++P + Sbjct: 306 EMTHNHNFRLNEREVVKVSMMQTKGNFLAANDQELDCDILQLEYVGG-ISMLIVVPHKMS 364 Query: 237 DLAVVEKALTYEKFKAWTNSEKLTKSKVQVFLPRLKLEESYDLEPFLRRLGMIDAFDEAK 296 + +E LT + W S +T +V LP+ KLE++Y+L L+ +G+ FD+ Sbjct: 365 GMKTLEAQLTPRVVERWQKS--MTNRTREVLLPKFKLEKNYNLVESLKLMGIRMLFDK-N 421 Query: 297 ADFSGMSTEKNVPLSKVAHKCFVEVNEEGTEAAAATAVVRNSRCSRMEPRFCADHPFLFF 356 + +G+S ++ + + H+ + VNEEGT+A T V +++ RF D PFLF Sbjct: 422 GNMAGISDQR-IAIDLFKHQGTITVNEEGTQATTVTTVGFMPLSTQV--RFTVDRPFLFL 478 Query: 357 IRHHKTNCILFCGRFSSP 374 I H+T+C+LF GR ++P Sbjct: 479 IYEHRTSCLLFMGRVANP 496 >gi|50659080 serpin peptidase inhibitor, clade A, member 3 precursor [Homo sapiens] Length = 423 Score = 177 bits (450), Expect = 1e-44 Identities = 125/379 (32%), Positives = 201/379 (53%), Gaps = 15/379 (3%) Query: 4 LCEANGTFAISLFKILGEEDNSRNVFFSPMSISSALAMVFMGAKGSTAAQMSQALCLY-- 61 L AN FA SL+K L + +NV FSP+SIS+ALA + +GA +T ++ + L Sbjct: 49 LASANVDFAFSLYKQLVLKAPDKNVIFSPLSISTALAFLSLGAHNTTLTEILKGLKFNLT 108 Query: 62 --KDGDIHRGFQSLLSEVNRTGTQYLLRTANRLFGEKTCDFLPDFKEYCQKFYQAELEEL 119 + +IH+ FQ LL +N++ + L N +F ++ L F E ++ Y +E Sbjct: 109 ETSEAEIHQSFQHLLRTLNQSSDELQLSMGNAMFVKEQLSLLDRFTEDAKRLYGSEAFAT 168 Query: 120 SFAEDTEECRKHINDWVAEKTEGKISEVLDAGTVDPLTKLVLVNAIYFKGKWNEQFDRKY 179 F +D+ +K IND+V T GKI++++ +D T +VLVN I+FK KW FD + Sbjct: 169 DF-QDSAAAKKLINDYVKNGTRGKITDLIK--DLDSQTMMVLVNYIFFKAKWEMPFDPQD 225 Query: 180 TRGMLFKTNEEKKTVQMMFKEAKFKMGYA--DEVHTQVLELPYVEEELSMVILLPDDNTD 237 T F +++K + M + Y +E+ V+EL Y S + +LPD + Sbjct: 226 THQSRFYLSKKKWVMVPMMSLHHLTIPYFRDEELSCTVVELKYTGNA-SALFILPDQDK- 283 Query: 238 LAVVEKALTYEKFKAWTNSEKLTKSKVQVFLPRLKLEESYDLEPFLRRLGMIDAFDEAKA 297 + VE L E K W +S + + +++LP+ + Y+L L +LG+ +AF +KA Sbjct: 284 MEEVEAMLLPETLKRWRDSLEFREIG-ELYLPKFSISRDYNLNDILLQLGIEEAFT-SKA 341 Query: 298 DFSGMSTEKNVPLSKVAHKCFVEVNEEGTEAAAATAVVRNSRCSRMEPRFCA--DHPFLF 355 D SG++ +N+ +S+V HK ++V EEGTEA+AATAV + +E R + PFL Sbjct: 342 DLSGITGARNLAVSQVVHKAVLDVFEEGTEASAATAVKITLLSALVETRTIVRFNRPFLM 401 Query: 356 FIRHHKTNCILFCGRFSSP 374 I T I F + ++P Sbjct: 402 IIVPTDTQNIFFMSKVTNP 420 >gi|189163542 serine proteinase inhibitor, clade A, member 1 [Homo sapiens] Length = 418 Score = 177 bits (449), Expect = 1e-44 Identities = 121/369 (32%), Positives = 193/369 (52%), Gaps = 15/369 (4%) Query: 11 FAISLFKILGEEDNSRNVFFSPMSISSALAMVFMGAKGSTAAQMSQALCL----YKDGDI 66 FA SL++ L + NS N+FFSP+SI++A AM+ +G K T ++ + L + I Sbjct: 57 FAFSLYRQLAHQSNSTNIFFSPVSIATAFAMLSLGTKADTHDEILEGLNFNLTEIPEAQI 116 Query: 67 HRGFQSLLSEVNRTGTQYLLRTANRLFGEKTCDFLPDFKEYCQKFYQAELEELSFAEDTE 126 H GFQ LL +N+ +Q L T N LF + + F E +K Y +E ++F DTE Sbjct: 117 HEGFQELLRTLNQPDSQLQLTTGNGLFLSEGLKLVDKFLEDVKKLYHSEAFTVNFG-DTE 175 Query: 127 ECRKHINDWVAEKTEGKISEVLDAGTVDPLTKLVLVNAIYFKGKWNEQFDRKYTRGMLFK 186 E +K IND+V + T+GKI +++ +D T LVN I+FKGKW F+ K T F Sbjct: 176 EAKKQINDYVEKGTQGKIVDLVK--ELDRDTVFALVNYIFFKGKWERPFEVKDTEEEDFH 233 Query: 187 TNEEKKT-VQMMFKEAKFKMGYADEVHTQVLELPYVEEELSMVILLPDDNTDLAVVEKAL 245 ++ V MM + F + + ++ + VL + Y+ + + LPD+ L +E L Sbjct: 234 VDQVTTVKVPMMKRLGMFNIQHCKKLSSWVLLMKYL-GNATAIFFLPDEG-KLQHLENEL 291 Query: 246 TYEKFKAWTNSEKLTKSKVQVFLPRLKLEESYDLEPFLRRLGMIDAFDEAKADFSGMSTE 305 T++ + +E + + LP+L + +YDL+ L +LG+ F AD SG++ E Sbjct: 292 THDIITKFLENE--DRRSASLHLPKLSITGTYDLKSVLGQLGITKVFSNG-ADLSGVTEE 348 Query: 306 KNVPLSKVAHKCFVEVNEEGTEAAAATAVVRNSRCSRMEPRFCADHPFLFFIRHHKTNCI 365 + LSK HK + ++E+GTEAA A + E +F + PF+F + T Sbjct: 349 APLKLSKAVHKAVLTIDEKGTEAAGAMFLEAIPMSIPPEVKF--NKPFVFLMIEQNTKSP 406 Query: 366 LFCGRFSSP 374 LF G+ +P Sbjct: 407 LFMGKVVNP 415 >gi|189163540 serine proteinase inhibitor, clade A, member 1 [Homo sapiens] Length = 418 Score = 177 bits (449), Expect = 1e-44 Identities = 121/369 (32%), Positives = 193/369 (52%), Gaps = 15/369 (4%) Query: 11 FAISLFKILGEEDNSRNVFFSPMSISSALAMVFMGAKGSTAAQMSQALCL----YKDGDI 66 FA SL++ L + NS N+FFSP+SI++A AM+ +G K T ++ + L + I Sbjct: 57 FAFSLYRQLAHQSNSTNIFFSPVSIATAFAMLSLGTKADTHDEILEGLNFNLTEIPEAQI 116 Query: 67 HRGFQSLLSEVNRTGTQYLLRTANRLFGEKTCDFLPDFKEYCQKFYQAELEELSFAEDTE 126 H GFQ LL +N+ +Q L T N LF + + F E +K Y +E ++F DTE Sbjct: 117 HEGFQELLRTLNQPDSQLQLTTGNGLFLSEGLKLVDKFLEDVKKLYHSEAFTVNFG-DTE 175 Query: 127 ECRKHINDWVAEKTEGKISEVLDAGTVDPLTKLVLVNAIYFKGKWNEQFDRKYTRGMLFK 186 E +K IND+V + T+GKI +++ +D T LVN I+FKGKW F+ K T F Sbjct: 176 EAKKQINDYVEKGTQGKIVDLVK--ELDRDTVFALVNYIFFKGKWERPFEVKDTEEEDFH 233 Query: 187 TNEEKKT-VQMMFKEAKFKMGYADEVHTQVLELPYVEEELSMVILLPDDNTDLAVVEKAL 245 ++ V MM + F + + ++ + VL + Y+ + + LPD+ L +E L Sbjct: 234 VDQVTTVKVPMMKRLGMFNIQHCKKLSSWVLLMKYL-GNATAIFFLPDEG-KLQHLENEL 291 Query: 246 TYEKFKAWTNSEKLTKSKVQVFLPRLKLEESYDLEPFLRRLGMIDAFDEAKADFSGMSTE 305 T++ + +E + + LP+L + +YDL+ L +LG+ F AD SG++ E Sbjct: 292 THDIITKFLENE--DRRSASLHLPKLSITGTYDLKSVLGQLGITKVFSNG-ADLSGVTEE 348 Query: 306 KNVPLSKVAHKCFVEVNEEGTEAAAATAVVRNSRCSRMEPRFCADHPFLFFIRHHKTNCI 365 + LSK HK + ++E+GTEAA A + E +F + PF+F + T Sbjct: 349 APLKLSKAVHKAVLTIDEKGTEAAGAMFLEAIPMSIPPEVKF--NKPFVFLMIEQNTKSP 406 Query: 366 LFCGRFSSP 374 LF G+ +P Sbjct: 407 LFMGKVVNP 415 >gi|189163538 serine proteinase inhibitor, clade A, member 1 [Homo sapiens] Length = 418 Score = 177 bits (449), Expect = 1e-44 Identities = 121/369 (32%), Positives = 193/369 (52%), Gaps = 15/369 (4%) Query: 11 FAISLFKILGEEDNSRNVFFSPMSISSALAMVFMGAKGSTAAQMSQALCL----YKDGDI 66 FA SL++ L + NS N+FFSP+SI++A AM+ +G K T ++ + L + I Sbjct: 57 FAFSLYRQLAHQSNSTNIFFSPVSIATAFAMLSLGTKADTHDEILEGLNFNLTEIPEAQI 116 Query: 67 HRGFQSLLSEVNRTGTQYLLRTANRLFGEKTCDFLPDFKEYCQKFYQAELEELSFAEDTE 126 H GFQ LL +N+ +Q L T N LF + + F E +K Y +E ++F DTE Sbjct: 117 HEGFQELLRTLNQPDSQLQLTTGNGLFLSEGLKLVDKFLEDVKKLYHSEAFTVNFG-DTE 175 Query: 127 ECRKHINDWVAEKTEGKISEVLDAGTVDPLTKLVLVNAIYFKGKWNEQFDRKYTRGMLFK 186 E +K IND+V + T+GKI +++ +D T LVN I+FKGKW F+ K T F Sbjct: 176 EAKKQINDYVEKGTQGKIVDLVK--ELDRDTVFALVNYIFFKGKWERPFEVKDTEEEDFH 233 Query: 187 TNEEKKT-VQMMFKEAKFKMGYADEVHTQVLELPYVEEELSMVILLPDDNTDLAVVEKAL 245 ++ V MM + F + + ++ + VL + Y+ + + LPD+ L +E L Sbjct: 234 VDQVTTVKVPMMKRLGMFNIQHCKKLSSWVLLMKYL-GNATAIFFLPDEG-KLQHLENEL 291 Query: 246 TYEKFKAWTNSEKLTKSKVQVFLPRLKLEESYDLEPFLRRLGMIDAFDEAKADFSGMSTE 305 T++ + +E + + LP+L + +YDL+ L +LG+ F AD SG++ E Sbjct: 292 THDIITKFLENE--DRRSASLHLPKLSITGTYDLKSVLGQLGITKVFSNG-ADLSGVTEE 348 Query: 306 KNVPLSKVAHKCFVEVNEEGTEAAAATAVVRNSRCSRMEPRFCADHPFLFFIRHHKTNCI 365 + LSK HK + ++E+GTEAA A + E +F + PF+F + T Sbjct: 349 APLKLSKAVHKAVLTIDEKGTEAAGAMFLEAIPMSIPPEVKF--NKPFVFLMIEQNTKSP 406 Query: 366 LFCGRFSSP 374 LF G+ +P Sbjct: 407 LFMGKVVNP 415 >gi|189163536 serine proteinase inhibitor, clade A, member 1 [Homo sapiens] Length = 418 Score = 177 bits (449), Expect = 1e-44 Identities = 121/369 (32%), Positives = 193/369 (52%), Gaps = 15/369 (4%) Query: 11 FAISLFKILGEEDNSRNVFFSPMSISSALAMVFMGAKGSTAAQMSQALCL----YKDGDI 66 FA SL++ L + NS N+FFSP+SI++A AM+ +G K T ++ + L + I Sbjct: 57 FAFSLYRQLAHQSNSTNIFFSPVSIATAFAMLSLGTKADTHDEILEGLNFNLTEIPEAQI 116 Query: 67 HRGFQSLLSEVNRTGTQYLLRTANRLFGEKTCDFLPDFKEYCQKFYQAELEELSFAEDTE 126 H GFQ LL +N+ +Q L T N LF + + F E +K Y +E ++F DTE Sbjct: 117 HEGFQELLRTLNQPDSQLQLTTGNGLFLSEGLKLVDKFLEDVKKLYHSEAFTVNFG-DTE 175 Query: 127 ECRKHINDWVAEKTEGKISEVLDAGTVDPLTKLVLVNAIYFKGKWNEQFDRKYTRGMLFK 186 E +K IND+V + T+GKI +++ +D T LVN I+FKGKW F+ K T F Sbjct: 176 EAKKQINDYVEKGTQGKIVDLVK--ELDRDTVFALVNYIFFKGKWERPFEVKDTEEEDFH 233 Query: 187 TNEEKKT-VQMMFKEAKFKMGYADEVHTQVLELPYVEEELSMVILLPDDNTDLAVVEKAL 245 ++ V MM + F + + ++ + VL + Y+ + + LPD+ L +E L Sbjct: 234 VDQVTTVKVPMMKRLGMFNIQHCKKLSSWVLLMKYL-GNATAIFFLPDEG-KLQHLENEL 291 Query: 246 TYEKFKAWTNSEKLTKSKVQVFLPRLKLEESYDLEPFLRRLGMIDAFDEAKADFSGMSTE 305 T++ + +E + + LP+L + +YDL+ L +LG+ F AD SG++ E Sbjct: 292 THDIITKFLENE--DRRSASLHLPKLSITGTYDLKSVLGQLGITKVFSNG-ADLSGVTEE 348 Query: 306 KNVPLSKVAHKCFVEVNEEGTEAAAATAVVRNSRCSRMEPRFCADHPFLFFIRHHKTNCI 365 + LSK HK + ++E+GTEAA A + E +F + PF+F + T Sbjct: 349 APLKLSKAVHKAVLTIDEKGTEAAGAMFLEAIPMSIPPEVKF--NKPFVFLMIEQNTKSP 406 Query: 366 LFCGRFSSP 374 LF G+ +P Sbjct: 407 LFMGKVVNP 415 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.320 0.134 0.393 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 12,814,859 Number of Sequences: 37866 Number of extensions: 515127 Number of successful extensions: 1648 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 60 Number of HSP's successfully gapped in prelim test: 10 Number of HSP's that attempted gapping in prelim test: 1346 Number of HSP's gapped (non-prelim): 78 length of query: 374 length of database: 18,247,518 effective HSP length: 104 effective length of query: 270 effective length of database: 14,309,454 effective search space: 3863552580 effective search space used: 3863552580 T: 11 A: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.