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Search of human proteins with 38504669
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|38504669 serine (or cysteine) proteinase inhibitor, clade B
(ovalbumin), member 8 isoform a [Homo sapiens]
(374 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|38504669 serine (or cysteine) proteinase inhibitor, clade B (... 755 0.0
gi|38504673 serine (or cysteine) proteinase inhibitor, clade B (... 755 0.0
gi|41152086 serine (or cysteine) proteinase inhibitor, clade B (... 501 e-142
gi|73623033 serine (or cysteine) proteinase inhibitor, clade B (... 485 e-137
gi|4758906 serpin peptidase inhibitor, clade B, member 9 [Homo s... 469 e-132
gi|13489087 serine (or cysteine) proteinase inhibitor, clade B (... 372 e-103
gi|219689110 serine (or cysteine) proteinase inhibitor, clade B ... 337 8e-93
gi|4505595 serine (or cysteine) proteinase inhibitor, clade B (o... 337 8e-93
gi|4826902 serine (or cysteine) proteinase inhibitor, clade B (o... 318 6e-87
gi|28076869 serine (or cysteine) proteinase inhibitor, clade B (... 311 5e-85
gi|5902072 serine (or cysteine) proteinase inhibitor, clade B (o... 309 2e-84
gi|156071456 serpin peptidase inhibitor, clade B, member 11 [Hom... 303 1e-82
gi|17998551 serine (or cysteine) proteinase inhibitor, clade B (... 295 3e-80
gi|8393956 serine (or cysteine) proteinase inhibitor, clade B (o... 284 8e-77
gi|167860126 serine (or cysteine) proteinase inhibitor, clade B ... 258 6e-69
gi|92859634 serine (or cysteine) proteinase inhibitor, clade B (... 253 1e-67
gi|4505149 serine (or cysteine) proteinase inhibitor, clade B (o... 253 1e-67
gi|4502261 serpin peptidase inhibitor, clade C, member 1 [Homo s... 234 7e-62
gi|170295807 neuroserpin precursor [Homo sapiens] 218 7e-57
gi|4826904 neuroserpin precursor [Homo sapiens] 218 7e-57
gi|5453886 serpin peptidase inhibitor, clade I (pancpin), member... 206 4e-53
gi|194018472 serine (or cysteine) proteinase inhibitor, clade A ... 186 2e-47
gi|110225347 serine (or cysteine) proteinase inhibitor, clade A ... 183 2e-46
gi|10835159 plasminogen activator inhibitor-1 [Homo sapiens] 182 3e-46
gi|73858566 heparin cofactor II precursor [Homo sapiens] 181 7e-46
gi|50659080 serpin peptidase inhibitor, clade A, member 3 precur... 177 1e-44
gi|189163542 serine proteinase inhibitor, clade A, member 1 [Hom... 177 1e-44
gi|189163540 serine proteinase inhibitor, clade A, member 1 [Hom... 177 1e-44
gi|189163538 serine proteinase inhibitor, clade A, member 1 [Hom... 177 1e-44
gi|189163536 serine proteinase inhibitor, clade A, member 1 [Hom... 177 1e-44
>gi|38504669 serine (or cysteine) proteinase inhibitor, clade B
(ovalbumin), member 8 isoform a [Homo sapiens]
Length = 374
Score = 755 bits (1950), Expect = 0.0
Identities = 374/374 (100%), Positives = 374/374 (100%)
Query: 1 MDDLCEANGTFAISLFKILGEEDNSRNVFFSPMSISSALAMVFMGAKGSTAAQMSQALCL 60
MDDLCEANGTFAISLFKILGEEDNSRNVFFSPMSISSALAMVFMGAKGSTAAQMSQALCL
Sbjct: 1 MDDLCEANGTFAISLFKILGEEDNSRNVFFSPMSISSALAMVFMGAKGSTAAQMSQALCL 60
Query: 61 YKDGDIHRGFQSLLSEVNRTGTQYLLRTANRLFGEKTCDFLPDFKEYCQKFYQAELEELS 120
YKDGDIHRGFQSLLSEVNRTGTQYLLRTANRLFGEKTCDFLPDFKEYCQKFYQAELEELS
Sbjct: 61 YKDGDIHRGFQSLLSEVNRTGTQYLLRTANRLFGEKTCDFLPDFKEYCQKFYQAELEELS 120
Query: 121 FAEDTEECRKHINDWVAEKTEGKISEVLDAGTVDPLTKLVLVNAIYFKGKWNEQFDRKYT 180
FAEDTEECRKHINDWVAEKTEGKISEVLDAGTVDPLTKLVLVNAIYFKGKWNEQFDRKYT
Sbjct: 121 FAEDTEECRKHINDWVAEKTEGKISEVLDAGTVDPLTKLVLVNAIYFKGKWNEQFDRKYT 180
Query: 181 RGMLFKTNEEKKTVQMMFKEAKFKMGYADEVHTQVLELPYVEEELSMVILLPDDNTDLAV 240
RGMLFKTNEEKKTVQMMFKEAKFKMGYADEVHTQVLELPYVEEELSMVILLPDDNTDLAV
Sbjct: 181 RGMLFKTNEEKKTVQMMFKEAKFKMGYADEVHTQVLELPYVEEELSMVILLPDDNTDLAV 240
Query: 241 VEKALTYEKFKAWTNSEKLTKSKVQVFLPRLKLEESYDLEPFLRRLGMIDAFDEAKADFS 300
VEKALTYEKFKAWTNSEKLTKSKVQVFLPRLKLEESYDLEPFLRRLGMIDAFDEAKADFS
Sbjct: 241 VEKALTYEKFKAWTNSEKLTKSKVQVFLPRLKLEESYDLEPFLRRLGMIDAFDEAKADFS 300
Query: 301 GMSTEKNVPLSKVAHKCFVEVNEEGTEAAAATAVVRNSRCSRMEPRFCADHPFLFFIRHH 360
GMSTEKNVPLSKVAHKCFVEVNEEGTEAAAATAVVRNSRCSRMEPRFCADHPFLFFIRHH
Sbjct: 301 GMSTEKNVPLSKVAHKCFVEVNEEGTEAAAATAVVRNSRCSRMEPRFCADHPFLFFIRHH 360
Query: 361 KTNCILFCGRFSSP 374
KTNCILFCGRFSSP
Sbjct: 361 KTNCILFCGRFSSP 374
>gi|38504673 serine (or cysteine) proteinase inhibitor, clade B
(ovalbumin), member 8 isoform a [Homo sapiens]
Length = 374
Score = 755 bits (1950), Expect = 0.0
Identities = 374/374 (100%), Positives = 374/374 (100%)
Query: 1 MDDLCEANGTFAISLFKILGEEDNSRNVFFSPMSISSALAMVFMGAKGSTAAQMSQALCL 60
MDDLCEANGTFAISLFKILGEEDNSRNVFFSPMSISSALAMVFMGAKGSTAAQMSQALCL
Sbjct: 1 MDDLCEANGTFAISLFKILGEEDNSRNVFFSPMSISSALAMVFMGAKGSTAAQMSQALCL 60
Query: 61 YKDGDIHRGFQSLLSEVNRTGTQYLLRTANRLFGEKTCDFLPDFKEYCQKFYQAELEELS 120
YKDGDIHRGFQSLLSEVNRTGTQYLLRTANRLFGEKTCDFLPDFKEYCQKFYQAELEELS
Sbjct: 61 YKDGDIHRGFQSLLSEVNRTGTQYLLRTANRLFGEKTCDFLPDFKEYCQKFYQAELEELS 120
Query: 121 FAEDTEECRKHINDWVAEKTEGKISEVLDAGTVDPLTKLVLVNAIYFKGKWNEQFDRKYT 180
FAEDTEECRKHINDWVAEKTEGKISEVLDAGTVDPLTKLVLVNAIYFKGKWNEQFDRKYT
Sbjct: 121 FAEDTEECRKHINDWVAEKTEGKISEVLDAGTVDPLTKLVLVNAIYFKGKWNEQFDRKYT 180
Query: 181 RGMLFKTNEEKKTVQMMFKEAKFKMGYADEVHTQVLELPYVEEELSMVILLPDDNTDLAV 240
RGMLFKTNEEKKTVQMMFKEAKFKMGYADEVHTQVLELPYVEEELSMVILLPDDNTDLAV
Sbjct: 181 RGMLFKTNEEKKTVQMMFKEAKFKMGYADEVHTQVLELPYVEEELSMVILLPDDNTDLAV 240
Query: 241 VEKALTYEKFKAWTNSEKLTKSKVQVFLPRLKLEESYDLEPFLRRLGMIDAFDEAKADFS 300
VEKALTYEKFKAWTNSEKLTKSKVQVFLPRLKLEESYDLEPFLRRLGMIDAFDEAKADFS
Sbjct: 241 VEKALTYEKFKAWTNSEKLTKSKVQVFLPRLKLEESYDLEPFLRRLGMIDAFDEAKADFS 300
Query: 301 GMSTEKNVPLSKVAHKCFVEVNEEGTEAAAATAVVRNSRCSRMEPRFCADHPFLFFIRHH 360
GMSTEKNVPLSKVAHKCFVEVNEEGTEAAAATAVVRNSRCSRMEPRFCADHPFLFFIRHH
Sbjct: 301 GMSTEKNVPLSKVAHKCFVEVNEEGTEAAAATAVVRNSRCSRMEPRFCADHPFLFFIRHH 360
Query: 361 KTNCILFCGRFSSP 374
KTNCILFCGRFSSP
Sbjct: 361 KTNCILFCGRFSSP 374
>gi|41152086 serine (or cysteine) proteinase inhibitor, clade B
(ovalbumin), member 6 [Homo sapiens]
Length = 376
Score = 501 bits (1291), Expect = e-142
Identities = 253/378 (66%), Positives = 303/378 (80%), Gaps = 6/378 (1%)
Query: 1 MDDLCEANGTFAISLFKILGEEDNSRNVFFSPMSISSALAMVFMGAKGSTAAQMSQALCL 60
MD L EANGTFA++L K LG+ DNS+NVFFSPMS+S ALAMV+MGAKG+TAAQM+Q L
Sbjct: 1 MDVLAEANGTFALNLLKTLGK-DNSKNVFFSPMSMSCALAMVYMGAKGNTAAQMAQILSF 59
Query: 61 YKDG---DIHRGFQSLLSEVNRTGTQYLLRTANRLFGEKTCDFLPDFKEYCQKFYQAELE 117
K G DIH+GFQSLL+EVN+TGTQYLLR ANRLFGEK+CDFL F++ CQKFYQAE+E
Sbjct: 60 NKSGGGGDIHQGFQSLLTEVNKTGTQYLLRMANRLFGEKSCDFLSSFRDSCQKFYQAEME 119
Query: 118 ELSFAEDTEECRKHINDWVAEKTEGKISEVLDAGTVDPLTKLVLVNAIYFKGKWNEQFDR 177
EL F E+ RKHIN WVAEKTEGKI+E+L G+VDPLT+LVLVNA+YF+G W+EQFD+
Sbjct: 120 ELDFISAVEKSRKHINTWVAEKTEGKIAELLSPGSVDPLTRLVLVNAVYFRGNWDEQFDK 179
Query: 178 KYTRGMLFKTNE-EKKTVQMMFKEAKFKMGYADEVHTQVLELPYVEEELSMVILLPDDNT 236
+ T LFK ++ E+K VQMMFK++ FK Y E+ TQ+L LPYV +EL+M+I+LPD+ T
Sbjct: 180 ENTEERLFKVSKNEEKPVQMMFKQSTFKKTYIGEIFTQILVLPYVGKELNMIIMLPDETT 239
Query: 237 DLAVVEKALTYEKFKAWTNSEKLTKSKVQVFLPRLKLEESYDLEPFLRRLGMIDAFDEAK 296
DL VEK LTYEKF WT + + + +V+V LPR KLEESYD+E LR LGM DAF+ K
Sbjct: 240 DLRTVEKELTYEKFVEWTRLDMMDEEEVEVSLPRFKLEESYDMESVLRNLGMTDAFELGK 299
Query: 297 ADFSGMSTEKNVPLSKVAHKCFVEVNEEGTEAAAATAVVRNSRCSRMEPRFCADHPFLFF 356
ADFSGMS + ++ LSKV HK FVEVNEEGTEAAAATA + RC+R PRFCADHPFLFF
Sbjct: 300 ADFSGMS-QTDLSLSKVVHKSFVEVNEEGTEAAAATAAIMMMRCARFVPRFCADHPFLFF 358
Query: 357 IRHHKTNCILFCGRFSSP 374
I+H KTN ILFCGRFSSP
Sbjct: 359 IQHSKTNGILFCGRFSSP 376
>gi|73623033 serine (or cysteine) proteinase inhibitor, clade B
(ovalbumin), member 8 isoform b [Homo sapiens]
Length = 242
Score = 485 bits (1248), Expect = e-137
Identities = 241/242 (99%), Positives = 241/242 (99%)
Query: 1 MDDLCEANGTFAISLFKILGEEDNSRNVFFSPMSISSALAMVFMGAKGSTAAQMSQALCL 60
MDDLCEANGTFAISLFKILGEEDNSRNVFFSPMSISSALAMVFMGAKGSTAAQMSQALCL
Sbjct: 1 MDDLCEANGTFAISLFKILGEEDNSRNVFFSPMSISSALAMVFMGAKGSTAAQMSQALCL 60
Query: 61 YKDGDIHRGFQSLLSEVNRTGTQYLLRTANRLFGEKTCDFLPDFKEYCQKFYQAELEELS 120
YKDGDIHRGFQSLLSEVNRTGTQYLLRTANRLFGEKTCDFLPDFKEYCQKFYQAELEELS
Sbjct: 61 YKDGDIHRGFQSLLSEVNRTGTQYLLRTANRLFGEKTCDFLPDFKEYCQKFYQAELEELS 120
Query: 121 FAEDTEECRKHINDWVAEKTEGKISEVLDAGTVDPLTKLVLVNAIYFKGKWNEQFDRKYT 180
FAEDTEECRKHINDWVAEKTEGKISEVLDAGTVDPLTKLVLVNAIYFKGKWNEQFDRKYT
Sbjct: 121 FAEDTEECRKHINDWVAEKTEGKISEVLDAGTVDPLTKLVLVNAIYFKGKWNEQFDRKYT 180
Query: 181 RGMLFKTNEEKKTVQMMFKEAKFKMGYADEVHTQVLELPYVEEELSMVILLPDDNTDLAV 240
RGMLFKTNEEKKTVQMMFKEAKFKMGYADEVHTQVLELPYVEEELSMVILLPDDNTDLAV
Sbjct: 181 RGMLFKTNEEKKTVQMMFKEAKFKMGYADEVHTQVLELPYVEEELSMVILLPDDNTDLAV 240
Query: 241 VE 242
E
Sbjct: 241 KE 242
>gi|4758906 serpin peptidase inhibitor, clade B, member 9 [Homo
sapiens]
Length = 376
Score = 469 bits (1206), Expect = e-132
Identities = 235/376 (62%), Positives = 288/376 (76%), Gaps = 2/376 (0%)
Query: 1 MDDLCEANGTFAISLFKILGEEDNSRNVFFSPMSISSALAMVFMGAKGSTAAQMSQALCL 60
M+ L A+GTFAI L KIL +++ S NVF SP+SISSALAMV +GAKG+TA QM+QAL L
Sbjct: 1 METLSNASGTFAIRLLKILCQDNPSHNVFCSPVSISSALAMVLLGAKGNTATQMAQALSL 60
Query: 61 YKDGDIHRGFQSLLSEVNRTGTQYLLRTANRLFGEKTCDFLPDFKEYCQKFYQAELEELS 120
+ DIHR FQSLL+EVN+ GTQYLLRTANRLFGEKTC FL FKE C +FY AEL+ELS
Sbjct: 61 NTEEDIHRAFQSLLTEVNKAGTQYLLRTANRLFGEKTCQFLSTFKESCLQFYHAELKELS 120
Query: 121 FAEDTEECRKHINDWVAEKTEGKISEVLDAGTVDPLTKLVLVNAIYFKGKWNEQFDRKYT 180
F EE RKHIN WV++KTEGKI E+L ++D T+LVLVNAIYFKGKWNE FD YT
Sbjct: 121 FIRAAEESRKHINTWVSKKTEGKIEELLPGSSIDAETRLVLVNAIYFKGKWNEPFDETYT 180
Query: 181 RGMLFKTN-EEKKTVQMMFKEAKFKMGYADEVHTQVLELPYVEEELSMVILLPDDNTDLA 239
R M FK N EE++ VQMM++EA FK+ + EV Q+LELPY +ELS+++LLPDD +L+
Sbjct: 181 REMPFKINQEEQRPVQMMYQEATFKLAHVGEVRAQLLELPYARKELSLLVLLPDDGVELS 240
Query: 240 VVEKALTYEKFKAWTNSEKLTKSKVQVFLPRLKLEESYDLEPFLRRLGMIDAFDEAKADF 299
VEK+LT+EK AWT + + ++V+V LP+ KL+E YD+E LR LG++DAF + KAD
Sbjct: 241 TVEKSLTFEKLTAWTKPDCMKSTEVEVLLPKFKLQEDYDMESVLRHLGIVDAFQQGKADL 300
Query: 300 SGMSTEKNVPLSKVAHKCFVEVNEEGTEAAAATA-VVRNSRCSRMEPRFCADHPFLFFIR 358
S MS E+++ LSK HK FVEVNEEGTEAAAA++ V C PRFCADHPFLFFIR
Sbjct: 301 SAMSAERDLCLSKFVHKSFVEVNEEGTEAAAASSCFVVAECCMESGPRFCADHPFLFFIR 360
Query: 359 HHKTNCILFCGRFSSP 374
H++ N ILFCGRFSSP
Sbjct: 361 HNRANSILFCGRFSSP 376
>gi|13489087 serine (or cysteine) proteinase inhibitor, clade B
(ovalbumin), member 1 [Homo sapiens]
Length = 379
Score = 372 bits (956), Expect = e-103
Identities = 197/379 (51%), Positives = 258/379 (68%), Gaps = 5/379 (1%)
Query: 1 MDDLCEANGTFAISLFKILGEEDNSRNVFFSPMSISSALAMVFMGAKGSTAAQMSQALCL 60
M+ L AN FA+ LF L E + + N+F SP SISSA+AMVF+G +G+TAAQ+S+
Sbjct: 1 MEQLSSANTRFALDLFLALSENNPAGNIFISPFSISSAMAMVFLGTRGNTAAQLSKTFHF 60
Query: 61 YKDGDIHRGFQSLLSEVNRTGTQYLLRTANRLFGEKTCDFLPDFKEYCQKFYQAELEELS 120
++H FQSL +++N+ G Y+L+ ANRL+GEKT +FLP+F QK Y A+L +
Sbjct: 61 NTVEEVHSRFQSLNADINKRGASYILKLANRLYGEKTYNFLPEFLVSTQKTYGADLASVD 120
Query: 121 FAEDTEECRKHINDWVAEKTEGKISEVLDAGTVDPLTKLVLVNAIYFKGKWNEQFDRKYT 180
F +E+ RK IN WV +TEGKI E+L +G VD +TKLVLVNAIYFKG W ++F ++ T
Sbjct: 121 FQHASEDARKTINQWVKGQTEGKIPELLASGMVDNMTKLVLVNAIYFKGNWKDKFMKEAT 180
Query: 181 RGMLFKTN-EEKKTVQMMFKEAKFKMGYADEVHTQVLELPYVEEELSMVILLPDD----N 235
F+ N +++KTV+MM+++ KF GY +++ +VLELPY EELSMVILLPDD +
Sbjct: 181 TNAPFRLNKKDRKTVKMMYQKKKFAYGYIEDLKCRVLELPYQGEELSMVILLPDDIEDES 240
Query: 236 TDLAVVEKALTYEKFKAWTNSEKLTKSKVQVFLPRLKLEESYDLEPFLRRLGMIDAFDEA 295
T L +E+ LT EK WT E L +V V LPR KLEESY L L RLG+ D F+ +
Sbjct: 241 TGLKKIEEQLTLEKLHEWTKPENLDFIEVNVSLPRFKLEESYTLNSDLARLGVQDLFNSS 300
Query: 296 KADFSGMSTEKNVPLSKVAHKCFVEVNEEGTEAAAATAVVRNSRCSRMEPRFCADHPFLF 355
KAD SGMS +++ +SK+ HK FVEVNEEGTEAAAATA + E F ADHPFLF
Sbjct: 301 KADLSGMSGARDIFISKIVHKSFVEVNEEGTEAAAATAGIATFCMLMPEENFTADHPFLF 360
Query: 356 FIRHHKTNCILFCGRFSSP 374
FIRH+ + ILF GRFSSP
Sbjct: 361 FIRHNSSGSILFLGRFSSP 379
>gi|219689110 serine (or cysteine) proteinase inhibitor, clade B
(ovalbumin), member 2 [Homo sapiens]
Length = 415
Score = 337 bits (865), Expect = 8e-93
Identities = 180/416 (43%), Positives = 254/416 (61%), Gaps = 43/416 (10%)
Query: 1 MDDLCEANGTFAISLFKILGEEDNSRNVFFSPMSISSALAMVFMGAKGSTAAQMSQALCL 60
M+DLC AN FA++LFK L + ++N+F SP SISS +AMV+MG++GST QM++ L
Sbjct: 1 MEDLCVANTLFALNLFKHLAKASPTQNLFLSPWSISSTMAMVYMGSRGSTEDQMAKVLQF 60
Query: 61 YKDG-------------------------------------DIHRGFQSLLSEVNRTGTQ 83
+ G IH F+SL S +N +
Sbjct: 61 NEVGANAVTPMTPENFTSCGFMQQIQKGSYPDAILQAQAADKIHSSFRSLSSAINASTGN 120
Query: 84 YLLRTANRLFGEKTCDFLPDFKEYCQKFYQAELEELSFAEDTEECRKHINDWVAEKTEGK 143
YLL + N+LFGEK+ F ++ CQK+Y +E + + F E EE RK IN WV +T+GK
Sbjct: 121 YLLESVNKLFGEKSASFREEYIRLCQKYYSSEPQAVDFLECAEEARKKINSWVKTQTKGK 180
Query: 144 ISEVLDAGTVDPLTKLVLVNAIYFKGKWNEQFDRKYTRGMLFKTNEEKKT-VQMMFKEAK 202
I +L G+VD T++VLVNA+YFKGKW F++K F+ N ++T VQMM+ K
Sbjct: 181 IPNLLPEGSVDGDTRMVLVNAVYFKGKWKTPFEKKLNGLYPFRVNSAQRTPVQMMYLREK 240
Query: 203 FKMGYADEVHTQVLELPYVEEELSMVILLPDD----NTDLAVVEKALTYEKFKAWTNSEK 258
+GY +++ Q+LELPY + +SM +LLPD+ +T L ++E +TY+K WT+ +K
Sbjct: 241 LNIGYIEDLKAQILELPYAGD-VSMFLLLPDEIADVSTGLELLESEITYDKLNKWTSKDK 299
Query: 259 LTKSKVQVFLPRLKLEESYDLEPFLRRLGMIDAFDEAKADFSGMSTEKNVPLSKVAHKCF 318
+ + +V+V++P+ KLEE Y+L LR +GM DAF++ +A+FSGMS ++ LS+V H+
Sbjct: 300 MAEDEVEVYIPQFKLEEHYELRSILRSMGMEDAFNKGRANFSGMSERNDLFLSEVFHQAM 359
Query: 319 VEVNEEGTEAAAATAVVRNSRCSRMEPRFCADHPFLFFIRHHKTNCILFCGRFSSP 374
V+VNEEGTEAAA T V R P+F ADHPFLF I H TNCILF GRFSSP
Sbjct: 360 VDVNEEGTEAAAGTGGVMTGRTGHGGPQFVADHPFLFLIMHKITNCILFFGRFSSP 415
>gi|4505595 serine (or cysteine) proteinase inhibitor, clade B
(ovalbumin), member 2 [Homo sapiens]
Length = 415
Score = 337 bits (865), Expect = 8e-93
Identities = 180/416 (43%), Positives = 254/416 (61%), Gaps = 43/416 (10%)
Query: 1 MDDLCEANGTFAISLFKILGEEDNSRNVFFSPMSISSALAMVFMGAKGSTAAQMSQALCL 60
M+DLC AN FA++LFK L + ++N+F SP SISS +AMV+MG++GST QM++ L
Sbjct: 1 MEDLCVANTLFALNLFKHLAKASPTQNLFLSPWSISSTMAMVYMGSRGSTEDQMAKVLQF 60
Query: 61 YKDG-------------------------------------DIHRGFQSLLSEVNRTGTQ 83
+ G IH F+SL S +N +
Sbjct: 61 NEVGANAVTPMTPENFTSCGFMQQIQKGSYPDAILQAQAADKIHSSFRSLSSAINASTGN 120
Query: 84 YLLRTANRLFGEKTCDFLPDFKEYCQKFYQAELEELSFAEDTEECRKHINDWVAEKTEGK 143
YLL + N+LFGEK+ F ++ CQK+Y +E + + F E EE RK IN WV +T+GK
Sbjct: 121 YLLESVNKLFGEKSASFREEYIRLCQKYYSSEPQAVDFLECAEEARKKINSWVKTQTKGK 180
Query: 144 ISEVLDAGTVDPLTKLVLVNAIYFKGKWNEQFDRKYTRGMLFKTNEEKKT-VQMMFKEAK 202
I +L G+VD T++VLVNA+YFKGKW F++K F+ N ++T VQMM+ K
Sbjct: 181 IPNLLPEGSVDGDTRMVLVNAVYFKGKWKTPFEKKLNGLYPFRVNSAQRTPVQMMYLREK 240
Query: 203 FKMGYADEVHTQVLELPYVEEELSMVILLPDD----NTDLAVVEKALTYEKFKAWTNSEK 258
+GY +++ Q+LELPY + +SM +LLPD+ +T L ++E +TY+K WT+ +K
Sbjct: 241 LNIGYIEDLKAQILELPYAGD-VSMFLLLPDEIADVSTGLELLESEITYDKLNKWTSKDK 299
Query: 259 LTKSKVQVFLPRLKLEESYDLEPFLRRLGMIDAFDEAKADFSGMSTEKNVPLSKVAHKCF 318
+ + +V+V++P+ KLEE Y+L LR +GM DAF++ +A+FSGMS ++ LS+V H+
Sbjct: 300 MAEDEVEVYIPQFKLEEHYELRSILRSMGMEDAFNKGRANFSGMSERNDLFLSEVFHQAM 359
Query: 319 VEVNEEGTEAAAATAVVRNSRCSRMEPRFCADHPFLFFIRHHKTNCILFCGRFSSP 374
V+VNEEGTEAAA T V R P+F ADHPFLF I H TNCILF GRFSSP
Sbjct: 360 VDVNEEGTEAAAGTGGVMTGRTGHGGPQFVADHPFLFLIMHKITNCILFFGRFSSP 415
>gi|4826902 serine (or cysteine) proteinase inhibitor, clade B
(ovalbumin), member 10 [Homo sapiens]
Length = 397
Score = 318 bits (814), Expect = 6e-87
Identities = 174/397 (43%), Positives = 246/397 (61%), Gaps = 23/397 (5%)
Query: 1 MDDLCEANGTFAISLFKILGEEDNSRNVFFSPMSISSALAMVFMGAKGSTAAQMSQALCL 60
MD L + FA+ L K L E +N+FFS SIS++L +V++GAKG+TAAQM+Q L
Sbjct: 1 MDSLATSINQFALELSKKLAESAQGKNIFFSSWSISTSLTIVYLGAKGTTAAQMAQVLQF 60
Query: 61 YKDG----------------------DIHRGFQSLLSEVNRTGTQYLLRTANRLFGEKTC 98
+D +IH FQ+L+SE+ + YLL+TAN ++GEKT
Sbjct: 61 NRDQGVKCDPESEKKRKMEFNLSNSEEIHSDFQTLISEILKPNDDYLLKTANAIYGEKTY 120
Query: 99 DFLPDFKEYCQKFYQAELEELSFAEDTEECRKHINDWVAEKTEGKISEVLDAGTVDPLTK 158
F + E + ++ AE + ++F E +++ RK IN WV +TEGKI +L +VD T+
Sbjct: 121 AFHNKYLEDMKTYFGAEPQPVNFVEASDQIRKDINSWVERQTEGKIQNLLPDDSVDSTTR 180
Query: 159 LVLVNAIYFKGKWNEQFDRKYTRGMLFKTNEE-KKTVQMMFKEAKFKMGYADEVHTQVLE 217
++LVNA+YFKG W QF + T F+ NE K VQMMF + K + + ++ L+
Sbjct: 181 MILVNALYFKGIWEHQFLVQNTTEKPFRINETTSKPVQMMFMKKKLHIFHIEKPKAVGLQ 240
Query: 218 LPYVEEELSMVILLPDDNTDLAVVEKALTYEKFKAWTNSEKLTKSKVQVFLPRLKLEESY 277
L Y +LS++ILLP+D L +EKA+TYEK WT+++ + +VQ+ LP+ KLE+SY
Sbjct: 241 LYYKSRDLSLLILLPEDINGLEQLEKAITYEKLNEWTSADMMELYEVQLHLPKFKLEDSY 300
Query: 278 DLEPFLRRLGMIDAFDEAKADFSGMSTEKNVPLSKVAHKCFVEVNEEGTEAAAATAVVRN 337
DL+ L +GM DAF ++KADFSGMS+ +N+ LS V HK FVE+NE+GTEAAA + +
Sbjct: 301 DLKSTLSSMGMSDAFSQSKADFSGMSSARNLFLSNVFHKAFVEINEQGTEAAAGSGSEID 360
Query: 338 SRCSRMEPRFCADHPFLFFIRHHKTNCILFCGRFSSP 374
R F A+HPFLFFIRH+KTN ILF GR SP
Sbjct: 361 IRIRVPSIEFNANHPFLFFIRHNKTNTILFYGRLCSP 397
>gi|28076869 serine (or cysteine) proteinase inhibitor, clade B
(ovalbumin), member 4 [Homo sapiens]
Length = 390
Score = 311 bits (798), Expect = 5e-85
Identities = 175/392 (44%), Positives = 240/392 (61%), Gaps = 20/392 (5%)
Query: 1 MDDLCEANGTFAISLFKILGEEDNSRNVFFSPMSISSALAMVFMGAKGSTAAQMSQALC- 59
M+ L EAN F LF+ + N+F+SP+SI+SAL MV +GAK +TA Q+S+ L
Sbjct: 1 MNSLSEANTKFMFDLFQQF-RKSKENNIFYSPISITSALGMVLLGAKDNTAQQISKVLHF 59
Query: 60 ---------------LYKDGDIHRGFQSLLSEVNRTGTQYLLRTANRLFGEKTCDFLPDF 104
+ + G++H FQ LL+E N++ Y L+ AN+LFGEKT FL ++
Sbjct: 60 DQVTENTTEKAATYHVDRSGNVHHQFQKLLTEFNKSTDAYELKIANKLFGEKTYQFLQEY 119
Query: 105 KEYCQKFYQAELEELSFAEDTEECRKHINDWVAEKTEGKISEVLDAGTVDPLTKLVLVNA 164
+ +KFYQ +E FA EE RK IN WV +T KI + GT+ T LVLVNA
Sbjct: 120 LDAIKKFYQTSVESTDFANAPEESRKKINSWVESQTNEKIKNLFPDGTIGNDTTLVLVNA 179
Query: 165 IYFKGKWNEQFDRKYTRGMLFKTNEEK-KTVQMMFKEAKFKMGYADEVHTQVLELPYVEE 223
IYFKG+W +F ++ T+ F N+ K+VQMM + F ++V +VLE+PY +
Sbjct: 180 IYFKGQWENKFKKENTKEEKFWPNKNTYKSVQMMRQYNSFNFALLEDVQAKVLEIPYKGK 239
Query: 224 ELSMVILLPDDNTDLAVVEKALTYEKFKAWTNSEKLTKSKVQVFLPRLKLEESYDLEPFL 283
+LSM++LLP++ L +E+ LT EK WT+ + + ++ V + LPR K+EESYDL+ L
Sbjct: 240 DLSMIVLLPNEIDGLQKLEEKLTAEKLMEWTSLQNMRETCVDLHLPRFKMEESYDLKDTL 299
Query: 284 RRLGMIDAFDEAKADFSGMSTEKNVPLSKVAHKCFVEVNEEGTEAAAATAVVRNSRCS-R 342
R +GM++ F+ AD SGM+ + +SKV HK FVEV EEG EAAAATAVV S
Sbjct: 300 RTMGMVNIFN-GDADLSGMTWSHGLSVSKVLHKAFVEVTEEGVEAAAATAVVVVELSSPS 358
Query: 343 MEPRFCADHPFLFFIRHHKTNCILFCGRFSSP 374
FC +HPFLFFIR +KTN ILF GRFSSP
Sbjct: 359 TNEEFCCNHPFLFFIRQNKTNSILFYGRFSSP 390
>gi|5902072 serine (or cysteine) proteinase inhibitor, clade B
(ovalbumin), member 3 [Homo sapiens]
Length = 390
Score = 309 bits (792), Expect = 2e-84
Identities = 172/392 (43%), Positives = 243/392 (61%), Gaps = 20/392 (5%)
Query: 1 MDDLCEANGTFAISLFKILGEEDNSRNVFFSPMSISSALAMVFMGAKGSTAAQMSQALC- 59
M+ L EAN F LF+ + N+F+SP+SI+SAL MV +GAK +TA Q+ + L
Sbjct: 1 MNSLSEANTKFMFDLFQQF-RKSKENNIFYSPISITSALGMVLLGAKDNTAQQIKKVLHF 59
Query: 60 ---------------LYKDGDIHRGFQSLLSEVNRTGTQYLLRTANRLFGEKTCDFLPDF 104
+ + G++H FQ LL+E N++ Y L+ AN+LFGEKT FL ++
Sbjct: 60 DQVTENTTGKAATYHVDRSGNVHHQFQKLLTEFNKSTDAYELKIANKLFGEKTYLFLQEY 119
Query: 105 KEYCQKFYQAELEELSFAEDTEECRKHINDWVAEKTEGKISEVLDAGTVDPLTKLVLVNA 164
+ +KFYQ +E + FA EE RK IN WV +T KI ++ G + T LVLVNA
Sbjct: 120 LDAIKKFYQTSVESVDFANAPEESRKKINSWVESQTNEKIKNLIPEGNIGSNTTLVLVNA 179
Query: 165 IYFKGKWNEQFDRKYTRGMLFKTNEEK-KTVQMMFKEAKFKMGYADEVHTQVLELPYVEE 223
IYFKG+W ++F+++ T+ F N+ K++QMM + F ++V +VLE+PY +
Sbjct: 180 IYFKGQWEKKFNKEDTKEEKFWPNKNTYKSIQMMRQYTSFHFASLEDVQAKVLEIPYKGK 239
Query: 224 ELSMVILLPDDNTDLAVVEKALTYEKFKAWTNSEKLTKSKVQVFLPRLKLEESYDLEPFL 283
+LSM++LLP++ L +E+ LT EK WT+ + + +++V + LPR K+EESYDL+ L
Sbjct: 240 DLSMIVLLPNEIDGLQKLEEKLTAEKLMEWTSLQNMRETRVDLHLPRFKVEESYDLKDTL 299
Query: 284 RRLGMIDAFDEAKADFSGMSTEKNVPLSKVAHKCFVEVNEEGTEAAAATAVVR-NSRCSR 342
R +GM+D F+ AD SGM+ + + LS V HK FVEV EEG EAAAATAVV S +
Sbjct: 300 RTMGMVDIFN-GDADLSGMTGSRGLVLSGVLHKAFVEVTEEGAEAAAATAVVGFGSSPTS 358
Query: 343 MEPRFCADHPFLFFIRHHKTNCILFCGRFSSP 374
F +HPFLFFIR +KTN ILF GRFSSP
Sbjct: 359 TNEEFHCNHPFLFFIRQNKTNSILFYGRFSSP 390
>gi|156071456 serpin peptidase inhibitor, clade B, member 11 [Homo
sapiens]
Length = 392
Score = 303 bits (777), Expect = 1e-82
Identities = 168/392 (42%), Positives = 231/392 (58%), Gaps = 18/392 (4%)
Query: 1 MDDLCEANGTFAISLFKILGEEDNSRNVFFSPMSISSALAMVFMGAKGSTAAQMSQALCL 60
M L AN F + +FK L + N+FFS +S+ AL+MV +GA+G T Q+ + L
Sbjct: 1 MGSLSTANVEFCLDVFKELNSNNIGDNIFFSSLSLLYALSMVLLGARGETEEQLEKVLHF 60
Query: 61 ----------YKD-------GDIHRGFQSLLSEVNRTGTQYLLRTANRLFGEKTCDFLPD 103
+KD G IH F S++N+ + L ANRL+G KT F
Sbjct: 61 SHTVDSLKPGFKDSPKCSQAGRIHSEFGVEFSQINQPDSNCTLSIANRLYGTKTMAFHQQ 120
Query: 104 FKEYCQKFYQAELEELSFAEDTEECRKHINDWVAEKTEGKISEVLDAGTVDPLTKLVLVN 163
+ +K+YQA L+ + F + TEE RK IN WV KT GK++ + T+DP + +VLVN
Sbjct: 121 YLSCSEKWYQARLQTVDFEQSTEETRKTINAWVENKTNGKVANLFGKSTIDPSSVMVLVN 180
Query: 164 AIYFKGKWNEQFDRKYTRGMLFKTNEEKK-TVQMMFKEAKFKMGYADEVHTQVLELPYVE 222
AIYFKG+W +F + T F+ +E K TV+MM++ FK+ + E QVLELPYV
Sbjct: 181 AIYFKGQWQNKFQVRETVKSPFQLSEGKNVTVEMMYQIGTFKLAFVKEPQMQVLELPYVN 240
Query: 223 EELSMVILLPDDNTDLAVVEKALTYEKFKAWTNSEKLTKSKVQVFLPRLKLEESYDLEPF 282
+LSM+ILLP +L +EK L F WT+S + + +V+V LPR KLE Y+L
Sbjct: 241 NKLSMIILLPVGIANLKQIEKQLNSGTFHEWTSSSNMMEREVEVHLPRFKLETKYELNSL 300
Query: 283 LRRLGMIDAFDEAKADFSGMSTEKNVPLSKVAHKCFVEVNEEGTEAAAATAVVRNSRCSR 342
L+ LG+ D F++ KAD SGMS K + LSK HK +++V+EEGTEAAAAT +
Sbjct: 301 LKSLGVTDLFNQVKADLSGMSPTKGLYLSKAIHKSYLDVSEEGTEAAAATGDSIAVKSLP 360
Query: 343 MEPRFCADHPFLFFIRHHKTNCILFCGRFSSP 374
M +F A+HPFLFFIRH TN ILFCG+ +SP
Sbjct: 361 MRAQFKANHPFLFFIRHTHTNTILFCGKLASP 392
>gi|17998551 serine (or cysteine) proteinase inhibitor, clade B
(ovalbumin), member 12 [Homo sapiens]
Length = 405
Score = 295 bits (756), Expect = 3e-80
Identities = 164/405 (40%), Positives = 241/405 (59%), Gaps = 31/405 (7%)
Query: 1 MDDLCEANGTFAISLFKILGEEDNSRNVFFSPMSISSALAMVFMGAKGSTAAQMSQAL-- 58
MD L AN F LF+ +G++D +N+FFSP+S+S+AL MV +GA+ +A Q+ + L
Sbjct: 1 MDSLVTANTKFCFDLFQEIGKDDRHKNIFFSPLSLSAALGMVRLGARSDSAHQIDEVLHF 60
Query: 59 -------------CL----YKDGDIHRG-------FQSLLSEVNRTGTQYLLRTANRLFG 94
CL K G ++ F LLS+++R T Y L ANRL+G
Sbjct: 61 NEFSQNESKEPDPCLKSNKQKAGSLNNESGLVSCYFGQLLSKLDRIKTDYTLSIANRLYG 120
Query: 95 EKTCDFLPDFKEYCQKFYQAELEELSFAEDTEECRKHINDWVAEKTEGKISEVLDAGTVD 154
E+ ++ + +FY +E + F ++ E+ R+ IN WV +++GKI E+ ++
Sbjct: 121 EQEFPICQEYLDGVIQFYHTTIESVDFQKNPEKSRQEINFWVECQSQGKIKELFSKDAIN 180
Query: 155 PLTKLVLVNAIYFKGKWNEQFDRKYTRGMLFKTN-EEKKTVQMMFKEAKFKMGYADEVHT 213
T LVLVNA+YFK KW FD + T F N E K+V+MM ++ +++G+ +EV
Sbjct: 181 AETVLVLVNAVYFKAKWETYFDHENTVDAPFCLNANENKSVKMMTQKGLYRIGFIEEVKA 240
Query: 214 QVLELPYVEEELSMVILLPDDNTD----LAVVEKALTYEKFKAWTNSEKLTKSKVQVFLP 269
Q+LE+ Y + +LSM +LLP + D L +E+ +TYEK AW++SE +++ V + P
Sbjct: 241 QILEMRYTKGKLSMFVLLPSHSKDNLKGLEELERKITYEKMVAWSSSENMSEESVVLSFP 300
Query: 270 RLKLEESYDLEPFLRRLGMIDAFDEAKADFSGMSTEKNVPLSKVAHKCFVEVNEEGTEAA 329
R LE+SYDL L+ +G+ D FDE +AD +G+S N+ LSK+ HK FVEV+E GT+AA
Sbjct: 301 RFTLEDSYDLNSILQDMGITDIFDETRADLTGISPSPNLYLSKIIHKTFVEVDENGTQAA 360
Query: 330 AATAVVRNSRCSRMEPRFCADHPFLFFIRHHKTNCILFCGRFSSP 374
AAT V + R R F A+HPFLFFIRH+KT ILF GR SP
Sbjct: 361 AATGAVVSERSLRSWVEFNANHPFLFFIRHNKTQTILFYGRVCSP 405
>gi|8393956 serine (or cysteine) proteinase inhibitor, clade B
(ovalbumin), member 13 [Homo sapiens]
Length = 391
Score = 284 bits (727), Expect = 8e-77
Identities = 154/392 (39%), Positives = 224/392 (57%), Gaps = 19/392 (4%)
Query: 1 MDDLCEANGTFAISLFKILGEEDNSRNVFFSPMSISSALAMVFMGAKGSTAAQMSQALCL 60
MD L + LFK L ++ N N+FFSP+ I +A+ MV +G +G+TA+Q+ +
Sbjct: 1 MDSLGAVSTRLGFDLFKEL-KKTNDGNIFFSPVGILTAIGMVLLGTRGATASQLEEVFHS 59
Query: 61 YKDGD-----------------IHRGFQSLLSEVNRTGTQYLLRTANRLFGEKTCDFLPD 103
K+ +H+ FQ L+E+++ Y L NRLFGEKT FL
Sbjct: 60 EKETKSSRIKAEEKEVIENTEAVHQQFQKFLTEISKLTNDYELNITNRLFGEKTYLFLQK 119
Query: 104 FKEYCQKFYQAELEELSFAEDTEECRKHINDWVAEKTEGKISEVLDAGTVDPLTKLVLVN 163
+ +Y +K+Y A LE + F +E RK IN WV KT KI ++ G++ TKLVLVN
Sbjct: 120 YLDYVEKYYHASLEPVDFVNAADESRKKINSWVESKTNEKIKDLFPDGSISSSTKLVLVN 179
Query: 164 AIYFKGKWNEQFDRKYTRGMLFKTNEE-KKTVQMMFKEAKFKMGYADEVHTQVLELPYVE 222
+YFKG+W+ +F ++ T+ F N+ K+VQMM + F + +++ ++L +PY
Sbjct: 180 MVYFKGQWDREFKKENTKEEKFWMNKSTSKSVQMMTQSHSFSFTFLEDLQAKILGIPYKN 239
Query: 223 EELSMVILLPDDNTDLAVVEKALTYEKFKAWTNSEKLTKSKVQVFLPRLKLEESYDLEPF 282
+LSM +LLP+D L + ++ EK WT+ + + KV + LPR ++E+ YDLE
Sbjct: 240 NDLSMFVLLPNDIDGLEKIIDKISPEKLVEWTSPGHMEERKVNLHLPRFEVEDGYDLEAV 299
Query: 283 LRRLGMIDAFDEAKADFSGMSTEKNVPLSKVAHKCFVEVNEEGTEAAAATAVVRNSRCSR 342
L +GM DAF E KAD+SGMS+ + K H FV V EEGTEAAAAT + +
Sbjct: 300 LAAMGMGDAFSEHKADYSGMSSGSGLYAQKFLHSSFVAVTEEGTEAAAATGIGFTVTSAP 359
Query: 343 MEPRFCADHPFLFFIRHHKTNCILFCGRFSSP 374
+HPFLFFIRH+++N ILF GRFSSP
Sbjct: 360 GHENVHCNHPFLFFIRHNESNSILFFGRFSSP 391
>gi|167860126 serine (or cysteine) proteinase inhibitor, clade B
(ovalbumin), member 5 [Homo sapiens]
Length = 375
Score = 258 bits (659), Expect = 6e-69
Identities = 143/379 (37%), Positives = 222/379 (58%), Gaps = 9/379 (2%)
Query: 1 MDDLCEANGTFAISLFKILGEEDNSRNVFFSPMSISSALAMVFMGAKGSTAAQMSQALCL 60
MD L AN FA+ LFK L E++ NV FSP+ +S++L++ +GAKG TA ++ Q L
Sbjct: 1 MDALQLANSAFAVDLFKQLCEKEPLGNVLFSPICLSTSLSLAQVGAKGDTANEIGQVLHF 60
Query: 61 YKDGDIHRGFQSLLSEVNRTGTQYLLRTANRLFGEKTCDFLPDFKEYCQKFYQAELEELS 120
D+ GFQ++ S+VN+ + Y L+ RL+ +K+ + +F ++ Y ELE +
Sbjct: 61 ENVKDVPFGFQTVTSDVNKLSSFYSLKLIKRLYVDKSLNLSTEFISSTKRPYAKELETVD 120
Query: 121 FAEDTEECRKHINDWVAEKTEGKISEVLDAGTVDPLTKLVLVNAIYFKGKWNEQFDRKYT 180
F + EE + IN+ + + T+G +L +V+ TK+++VNA YF GKW ++F T
Sbjct: 121 FKDKLEETKGQINNSIKDLTDGHFENILADNSVNDQTKILVVNAAYFVGKWMKKFSESET 180
Query: 181 RGMLFKTNE-EKKTVQMMFKEAKFKMGYADEVHTQVLELPYVEEELSMVILLP----DDN 235
+ F+ N+ + K VQMM EA F MG D ++ +++ELP+ + LSM ILLP D++
Sbjct: 181 KECPFRVNKTDTKPVQMMNMEATFCMGNIDSINCKIIELPFQNKHLSMFILLPKDVEDES 240
Query: 236 TDLAVVEKALTYEKFKAWTNSEKLTKSKVQVFLPRLKLEESYDLEPFLRRLGMIDAFDEA 295
T L +EK L E WTN + +KV++ +P+ K+E+ D + L LG+ F E
Sbjct: 241 TGLEKIEKQLNSESLSQWTNPSTMANAKVKLSIPKFKVEKMIDPKACLENLGLKHIFSED 300
Query: 296 KADFSGMSTEKNVPLSKVAHKCFVEVNEEGTEAAAATAVVRNSRCSRMEPRFCADHPFLF 355
+DFSGMS K V LS V HK +E+ E+G ++ V +R + + ADHPF++
Sbjct: 301 TSDFSGMSETKGVALSNVIHKVCLEITEDGGDSIE----VPGARILQHKDELNADHPFIY 356
Query: 356 FIRHHKTNCILFCGRFSSP 374
IRH+KT I+F G+F SP
Sbjct: 357 IIRHNKTRNIIFFGKFCSP 375
>gi|92859634 serine (or cysteine) proteinase inhibitor, clade B
(ovalbumin), member 7 [Homo sapiens]
Length = 380
Score = 253 bits (647), Expect = 1e-67
Identities = 144/385 (37%), Positives = 220/385 (57%), Gaps = 16/385 (4%)
Query: 1 MDDLCEANGTFAISLFKILGEEDNSRNVFFSPMSISSALAMVFMGAKGSTAAQMSQALCL 60
M L AN F +LF+ + + + NVFFS +S+ +ALA+V +GA+ + +Q+ + L +
Sbjct: 1 MASLAAANAEFCFNLFREMDDNQGNGNVFFSSLSLFAALALVRLGAQDDSLSQIDKLLHV 60
Query: 61 Y------KDGDIHRGFQSLL----SEVNRTGTQYLLRTANRLFGEKTCDFLPDFKEYCQK 110
+ G QS L S++N + Y L N LF EK F D+ E +K
Sbjct: 61 NTASGYGNSSNSQSGLQSQLKRVFSDINASHKDYDLSIVNGLFAEKVYGFHKDYIECAEK 120
Query: 111 FYQAELEELSFAEDTEECRKHINDWVAEKTEGKISEVLDAGTVDPLTKLVLVNAIYFKGK 170
Y A++E + F E+ R++IN WV +T GKI V+ G + +VLVNA+YFKGK
Sbjct: 121 LYDAKVERVDFTNHLEDTRRNINKWVENETHGKIKNVIGEGGISSSAVMVLVNAVYFKGK 180
Query: 171 WNEQFDRKYTRGMLFKTNE-EKKTVQMMFKEAKFKMGYADEVHTQVLELPYVEEELSMVI 229
W F + T FK+ + K V MM +E KF + ++ ++LEL Y ++M +
Sbjct: 181 WQSAFTKSETINCHFKSPKCSGKAVAMMHQERKFNLSVIEDPSMKILELRY-NGGINMYV 239
Query: 230 LLPDDNTDLAVVEKALTYEKFKAWTNSEKLTKSKVQVFLPRLKLEESYDLEPFLRRLGMI 289
LLP++ DL+ +E LT++ WTN ++T V+VF P+ K+E++Y+++ +LR LG+
Sbjct: 240 LLPEN--DLSEIENKLTFQNLMEWTNPRRMTSKYVEVFFPQFKIEKNYEMKQYLRALGLK 297
Query: 290 DAFDEAKADFSGMSTEKNVPLSKVAHKCFVEVNEEGTEAAAATAVVRNSRCSRMEPRFCA 349
D FDE+KAD SG+++ + +S++ HK ++EV EEGTEA AAT + F A
Sbjct: 298 DIFDESKADLSGIASGGRLYISRMMHKSYIEVTEEGTEATAATGSNIVEKQLPQSTLFRA 357
Query: 350 DHPFLFFIRHHKTNCILFCGRFSSP 374
DHPFLF IR K + ILF G+ S P
Sbjct: 358 DHPFLFVIR--KDDIILFSGKVSCP 380
>gi|4505149 serine (or cysteine) proteinase inhibitor, clade B
(ovalbumin), member 7 [Homo sapiens]
Length = 380
Score = 253 bits (647), Expect = 1e-67
Identities = 144/385 (37%), Positives = 220/385 (57%), Gaps = 16/385 (4%)
Query: 1 MDDLCEANGTFAISLFKILGEEDNSRNVFFSPMSISSALAMVFMGAKGSTAAQMSQALCL 60
M L AN F +LF+ + + + NVFFS +S+ +ALA+V +GA+ + +Q+ + L +
Sbjct: 1 MASLAAANAEFCFNLFREMDDNQGNGNVFFSSLSLFAALALVRLGAQDDSLSQIDKLLHV 60
Query: 61 Y------KDGDIHRGFQSLL----SEVNRTGTQYLLRTANRLFGEKTCDFLPDFKEYCQK 110
+ G QS L S++N + Y L N LF EK F D+ E +K
Sbjct: 61 NTASGYGNSSNSQSGLQSQLKRVFSDINASHKDYDLSIVNGLFAEKVYGFHKDYIECAEK 120
Query: 111 FYQAELEELSFAEDTEECRKHINDWVAEKTEGKISEVLDAGTVDPLTKLVLVNAIYFKGK 170
Y A++E + F E+ R++IN WV +T GKI V+ G + +VLVNA+YFKGK
Sbjct: 121 LYDAKVERVDFTNHLEDTRRNINKWVENETHGKIKNVIGEGGISSSAVMVLVNAVYFKGK 180
Query: 171 WNEQFDRKYTRGMLFKTNE-EKKTVQMMFKEAKFKMGYADEVHTQVLELPYVEEELSMVI 229
W F + T FK+ + K V MM +E KF + ++ ++LEL Y ++M +
Sbjct: 181 WQSAFTKSETINCHFKSPKCSGKAVAMMHQERKFNLSVIEDPSMKILELRY-NGGINMYV 239
Query: 230 LLPDDNTDLAVVEKALTYEKFKAWTNSEKLTKSKVQVFLPRLKLEESYDLEPFLRRLGMI 289
LLP++ DL+ +E LT++ WTN ++T V+VF P+ K+E++Y+++ +LR LG+
Sbjct: 240 LLPEN--DLSEIENKLTFQNLMEWTNPRRMTSKYVEVFFPQFKIEKNYEMKQYLRALGLK 297
Query: 290 DAFDEAKADFSGMSTEKNVPLSKVAHKCFVEVNEEGTEAAAATAVVRNSRCSRMEPRFCA 349
D FDE+KAD SG+++ + +S++ HK ++EV EEGTEA AAT + F A
Sbjct: 298 DIFDESKADLSGIASGGRLYISRMMHKSYIEVTEEGTEATAATGSNIVEKQLPQSTLFRA 357
Query: 350 DHPFLFFIRHHKTNCILFCGRFSSP 374
DHPFLF IR K + ILF G+ S P
Sbjct: 358 DHPFLFVIR--KDDIILFSGKVSCP 380
>gi|4502261 serpin peptidase inhibitor, clade C, member 1 [Homo
sapiens]
Length = 464
Score = 234 bits (598), Expect = 7e-62
Identities = 147/383 (38%), Positives = 222/383 (57%), Gaps = 14/383 (3%)
Query: 3 DLCEANGTFAISLFKILGEEDNSR-NVFFSPMSISSALAMVFMGAKGSTAAQMSQALCL- 60
+L +AN FA + ++ L + N N+F SP+SIS+A AM +GA T Q+ +
Sbjct: 82 ELSKANSRFATTFYQHLADSKNDNDNIFLSPLSISTAFAMTKLGACNDTLQQLMEVFKFD 141
Query: 61 ---YKDGD-IHRGFQSLLSEVNRTGTQYL-LRTANRLFGEKTCDFLPDFKEYCQKFYQAE 115
K D IH F L + R + L +ANRLFG+K+ F +++ + Y A+
Sbjct: 142 TISEKTSDQIHFFFAKLNCRLYRKANKSSKLVSANRLFGDKSLTFNETYQDISELVYGAK 201
Query: 116 LEELSFAEDTEECRKHINDWVAEKTEGKISEVLDAGTVDPLTKLVLVNAIYFKGKWNEQF 175
L+ L F E+ E+ R IN WV+ KTEG+I++V+ + ++ LT LVLVN IYFKG W +F
Sbjct: 202 LQPLDFKENAEQSRAAINKWVSNKTEGRITDVIPSEAINELTVLVLVNTIYFKGLWKSKF 261
Query: 176 DRKYTRGMLF-KTNEEKKTVQMMFKEAKFKMGYADEVHTQVLELPYVEEELSMVILLPDD 234
+ TR LF K + E + MM++E KF+ E TQVLELP+ ++++MV++LP
Sbjct: 262 SPENTRKELFYKADGESCSASMMYQEGKFRYRRVAE-GTQVLELPFKGDDITMVLILPKP 320
Query: 235 NTDLAVVEKALTYEKFKAWTNSEKLTKSKVQVFLPRLKLEESYDLEPFLRRLGMIDAFDE 294
LA VEK LT E + W ++L + + V +PR ++E+ + L+ L+ +G++D F
Sbjct: 321 EKSLAKVEKELTPEVLQEWL--DELEEMMLVVHMPRFRIEDGFSLKEQLQDMGLVDLFSP 378
Query: 295 AKADFSGMSTE--KNVPLSKVAHKCFVEVNEEGTEAAAATAVVRNSR-CSRMEPRFCADH 351
K+ G+ E ++ +S HK F+EVNEEG+EAAA+TAVV R + F A+
Sbjct: 379 EKSKLPGIVAEGRDDLYVSDAFHKAFLEVNEEGSEAAASTAVVIAGRSLNPNRVTFKANR 438
Query: 352 PFLFFIRHHKTNCILFCGRFSSP 374
PFL FIR N I+F GR ++P
Sbjct: 439 PFLVFIREVPLNTIIFMGRVANP 461
>gi|170295807 neuroserpin precursor [Homo sapiens]
Length = 410
Score = 218 bits (555), Expect = 7e-57
Identities = 125/378 (33%), Positives = 211/378 (55%), Gaps = 13/378 (3%)
Query: 6 EANGTFAISLFKILGEEDNSRNVFFSPMSISSALAMVFMGAKGSTAAQMSQALCL--YKD 63
EA +++++ L N+ FSP+SI+ A+ M+ +GA+GST ++ ++ K+
Sbjct: 24 EAIADLSVNMYNRLRATGEDENILFSPLSIALAMGMMELGAQGSTQKEIRHSMGYDSLKN 83
Query: 64 GDIHRGFQSLLSEVNRTGTQYLLRTANRLFGEKTCDFLPDFKEYCQKFYQAELEELSFAE 123
G+ + + V +QY+++ AN LF + +F + +K++ A + + F++
Sbjct: 84 GEEFSFLKEFSNMVTAKESQYVMKIANSLFVQNGFHVNEEFLQMMKKYFNAAVNHVDFSQ 143
Query: 124 DTEECRKHINDWVAEKTEGKISEVLDAGTVDPLTKLVLVNAIYFKGKWNEQFDRKYTRGM 183
+ +IN WV T + +++ D T L L+NA+YFKG W QF + TR
Sbjct: 144 NVAVAN-YINKWVENNTNNLVKDLVSPRDFDAATYLALINAVYFKGNWKSQFRPENTRTF 202
Query: 184 LF-KTNEEKKTVQMMFKEAKFKMG-YADEVHT-----QVLELPYVEEELSMVILLPDDNT 236
F K +E + + MM+++ +F G ++D + QVLE+PY +E+SM+++L
Sbjct: 203 SFTKDDESEVQIPMMYQQGEFYYGEFSDGSNEAGGIYQVLEIPYEGDEISMMLVLSRQEV 262
Query: 237 DLAVVEKALTYEKFKAWTNSEKLTKSKVQVFLPRLKLEESYDLEPFLRRLGMIDAFDEAK 296
LA +E + + + W NS K K KV+V+LPR +E+ DL+ L+ LG+ + F +
Sbjct: 263 PLATLEPLVKAQLVEEWANSVK--KQKVEVYLPRFTVEQEIDLKDVLKALGITEIFIK-D 319
Query: 297 ADFSGMSTEKNVPLSKVAHKCFVEVNEEGTEAAAATAVVRNSRCSRMEPRFCADHPFLFF 356
A+ +G+S K + LSK HK F+EVNEEG+EAAA + ++ SR + + P+ DHPF F
Sbjct: 320 ANLTGLSDNKEIFLSKAIHKSFLEVNEEGSEAAAVSGMIAISRMAVLYPQVIVDHPFFFL 379
Query: 357 IRHHKTNCILFCGRFSSP 374
IR+ +T ILF GR P
Sbjct: 380 IRNRRTGTILFMGRVMHP 397
>gi|4826904 neuroserpin precursor [Homo sapiens]
Length = 410
Score = 218 bits (555), Expect = 7e-57
Identities = 125/378 (33%), Positives = 211/378 (55%), Gaps = 13/378 (3%)
Query: 6 EANGTFAISLFKILGEEDNSRNVFFSPMSISSALAMVFMGAKGSTAAQMSQALCL--YKD 63
EA +++++ L N+ FSP+SI+ A+ M+ +GA+GST ++ ++ K+
Sbjct: 24 EAIADLSVNMYNRLRATGEDENILFSPLSIALAMGMMELGAQGSTQKEIRHSMGYDSLKN 83
Query: 64 GDIHRGFQSLLSEVNRTGTQYLLRTANRLFGEKTCDFLPDFKEYCQKFYQAELEELSFAE 123
G+ + + V +QY+++ AN LF + +F + +K++ A + + F++
Sbjct: 84 GEEFSFLKEFSNMVTAKESQYVMKIANSLFVQNGFHVNEEFLQMMKKYFNAAVNHVDFSQ 143
Query: 124 DTEECRKHINDWVAEKTEGKISEVLDAGTVDPLTKLVLVNAIYFKGKWNEQFDRKYTRGM 183
+ +IN WV T + +++ D T L L+NA+YFKG W QF + TR
Sbjct: 144 NVAVAN-YINKWVENNTNNLVKDLVSPRDFDAATYLALINAVYFKGNWKSQFRPENTRTF 202
Query: 184 LF-KTNEEKKTVQMMFKEAKFKMG-YADEVHT-----QVLELPYVEEELSMVILLPDDNT 236
F K +E + + MM+++ +F G ++D + QVLE+PY +E+SM+++L
Sbjct: 203 SFTKDDESEVQIPMMYQQGEFYYGEFSDGSNEAGGIYQVLEIPYEGDEISMMLVLSRQEV 262
Query: 237 DLAVVEKALTYEKFKAWTNSEKLTKSKVQVFLPRLKLEESYDLEPFLRRLGMIDAFDEAK 296
LA +E + + + W NS K K KV+V+LPR +E+ DL+ L+ LG+ + F +
Sbjct: 263 PLATLEPLVKAQLVEEWANSVK--KQKVEVYLPRFTVEQEIDLKDVLKALGITEIFIK-D 319
Query: 297 ADFSGMSTEKNVPLSKVAHKCFVEVNEEGTEAAAATAVVRNSRCSRMEPRFCADHPFLFF 356
A+ +G+S K + LSK HK F+EVNEEG+EAAA + ++ SR + + P+ DHPF F
Sbjct: 320 ANLTGLSDNKEIFLSKAIHKSFLEVNEEGSEAAAVSGMIAISRMAVLYPQVIVDHPFFFL 379
Query: 357 IRHHKTNCILFCGRFSSP 374
IR+ +T ILF GR P
Sbjct: 380 IRNRRTGTILFMGRVMHP 397
>gi|5453886 serpin peptidase inhibitor, clade I (pancpin), member 2
[Homo sapiens]
Length = 405
Score = 206 bits (523), Expect = 4e-53
Identities = 123/374 (32%), Positives = 207/374 (55%), Gaps = 10/374 (2%)
Query: 6 EANGTFAISLFKILGEEDNSRNVFFSPMSISSALAMVFMGAKGSTAAQMSQALCLYKD-- 63
+ N FA+ L++ + N+ FSP+ I+ L MV +GAKG Q+ Q L +
Sbjct: 24 QKNTEFAVDLYQEVSLSHKD-NIIFSPLGITLVLEMVQLGAKGKAQQQIRQTLKQQETSA 82
Query: 64 GDIHRGFQSLLSEVNRTGTQYLLRTANRLFGEKTCDFLPDFKEYCQKFYQAELEELSFAE 123
G+ +S S ++ ++ AN L+ ++ + ++F+Q+ ++ + F +
Sbjct: 83 GEEFFVLKSFFSAISEKKQEFTFNLANALYLQEGFTVKEQYLHGNKEFFQSAIKLVDF-Q 141
Query: 124 DTEECRKHINDWVAEKTEGKISEVLDAGTVDPLTKLVLVNAIYFKGKWNEQFDRKYTRGM 183
D + C + I+ WV KT+GKI ++ PLT+LVLVNAIYFKG W ++F ++ T+ +
Sbjct: 142 DAKACAEMISTWVERKTDGKIKDMFSGEEFGPLTRLVLVNAIYFKGDWKQKFRKEDTQLI 201
Query: 184 LF-KTNEEKKTVQMMFKEAKFKMGYADE--VHTQVLELPYVEEELSMVILLPDDNTDLAV 240
F K N + MM + K GY E ++ QVLEL Y +E S++I+LP + D+
Sbjct: 202 NFTKKNGSTVKIPMMKALLRTKYGYFSESSLNYQVLELSYKGDEFSLIIILPAEGMDIEE 261
Query: 241 VEKALTYEKFKAWTNSEKLTKSKVQVFLPRLKLEESYDLEPFLRRLGMIDAFDEAKADFS 300
VEK +T ++ W + ++ + +V++ LPR K+E+ D + L L + + F D S
Sbjct: 262 VEKLITAQQILKWLS--EMQEEEVEISLPRFKVEQKVDFKDVLYSLNITEIFSGG-CDLS 318
Query: 301 GMSTEKNVPLSKVAHKCFVEVNEEGTEAAAATAVVRNSRCSRMEPRFCADHPFLFFIRHH 360
G++ V +S+V K F E+NE+G+EAA +T + S + +F A+HPFLF ++H+
Sbjct: 319 GITDSSEVYVSQVTQKVFFEINEDGSEAATSTGIHIPVIMSLAQSQFIANHPFLFIMKHN 378
Query: 361 KTNCILFCGRFSSP 374
T ILF GR ++P
Sbjct: 379 PTESILFMGRVTNP 392
>gi|194018472 serine (or cysteine) proteinase inhibitor, clade A
(alpha-1 antiproteinase, antitrypsin), member 5 [Homo
sapiens]
Length = 406
Score = 186 bits (473), Expect = 2e-47
Identities = 124/370 (33%), Positives = 199/370 (53%), Gaps = 17/370 (4%)
Query: 11 FAISLFKILGEEDNSRNVFFSPMSISSALAMVFMGAKGSTAAQMSQALCLY----KDGDI 66
F L++ L S+++FFSP+SIS +LAM+ +GA ST Q+ + L L + ++
Sbjct: 48 FTFDLYRALASAAPSQSIFFSPVSISMSLAMLSLGAGSSTKMQILEGLGLNLQKSSEKEL 107
Query: 67 HRGFQSLLSEVNRTGTQYLLRTANRLFGEKTCDFLPDFKEYCQKFYQAELEELSFAEDTE 126
HRGFQ LL E+N+ + L N LF + D F + Y A+ +F D+
Sbjct: 108 HRGFQQLLQELNQPRDGFQLSLGNALFTDLVVDLQDTFVSAMKTLYLADTFPTNF-RDSA 166
Query: 127 ECRKHINDWVAEKTEGKISEVLDAGTVDPLTKLVLVNAIYFKGKWNEQFDRKYTRGM-LF 185
K IND+VA++T+GKI ++L +D +++VN I+FK KW F+ K T+ +
Sbjct: 167 GAMKQINDYVAKQTKGKIVDLLK--NLDSNAVVIMVNYIFFKAKWETSFNHKGTQEQDFY 224
Query: 186 KTNEEKKTVQMMFKEAKFKMGYADEVHTQVLELPYVEEELSMVILLPDDNTDLAVVEKAL 245
T+E V MM +E ++ + +V+ +PY + + + +LP + + VE L
Sbjct: 225 VTSETVVRVPMMSREDQYHYLLDRNLSCRVVGVPY-QGNATALFILPSEGK-MQQVENGL 282
Query: 246 TYEKFKAWTNSEKLTKSKVQVFLPRLKLEESYDLEPFLRRLGMIDAFDEAKADFSGMSTE 305
+ + + W K K +++++LP+ +E SY LE L LG+ + F + AD SG+S
Sbjct: 283 SEKTLRKWLKMFK--KRQLELYLPKFSIEGSYQLEKVLPSLGISNVFT-SHADLSGISNH 339
Query: 306 KNVPLSKVAHKCFVEVNEEGTEAAAATAVVRNSRCSRM-EPRFCADHPFLFFIRHHKTNC 364
N+ +S++ HK VEV+E GT AAAAT + R +R+ R + PFL FI N
Sbjct: 340 SNIQVSEMVHKAVVEVDESGTRAAAATGTIFTFRSARLNSQRLVFNRPFLMFI---VDNN 396
Query: 365 ILFCGRFSSP 374
ILF G+ + P
Sbjct: 397 ILFLGKVNRP 406
>gi|110225347 serine (or cysteine) proteinase inhibitor, clade A
(alpha-1 antiproteinase, antitrypsin), member 9 isoform
A [Homo sapiens]
Length = 435
Score = 183 bits (465), Expect = 2e-46
Identities = 124/379 (32%), Positives = 206/379 (54%), Gaps = 24/379 (6%)
Query: 8 NGTFAISLFKILGEEDNSRNVFFSPMSISSALAMVFMGAKGSTAAQMSQALCL----YKD 63
N FA L++ L E S+N+FFSP+S+S++LAM+ +GA T Q+ Q L +
Sbjct: 66 NTDFAFRLYRRLVLETPSQNIFFSPVSVSTSLAMLSLGAHSVTKTQILQGLGFNLTHTPE 125
Query: 64 GDIHRGFQSLLSEVNRTGTQYLLRTANRLFGEKTCDFLPDFKEYCQKFYQAELEELSFAE 123
IH+GFQ L+ + L+ + LF +K +F ++ Y+AE+ F+
Sbjct: 126 SAIHQGFQHLVHSLTVPSKDLTLKMGSALFVKKELQLQANFLGNVKRLYEAEVFSTDFS- 184
Query: 124 DTEECRKHINDWVAEKTEGKISEVLDAGTVDPLTKLVLVNAIYFKGKWNEQFDRKYTR-G 182
+ + IN V +KT+GK+ +++ +D LT +VLVN I+FK KW + F +YTR
Sbjct: 185 NPSIAQARINSHVKKKTQGKVVDIIQG--LDLLTAMVLVNHIFFKAKWEKPFHPEYTRKN 242
Query: 183 MLFKTNEEKKT-VQMMFKEAKFKMGYADEVHTQVLELPYVEEELSMVILLPDDNTDLAVV 241
F E+ V MM ++ +F G E++ VL++ Y + ++ +L + +
Sbjct: 243 FPFLVGEQVTVHVPMMHQKEQFAFGVDTELNCFVLQMDYKGDAVAFFVL--PSKGKMRQL 300
Query: 242 EKALTYEKFKAWTNSEKLTKSKVQVFLPRLKLEESYDLEPFLRRLGMIDAFDEAKADFSG 301
E+AL+ + W++S L K ++VF+PR + SY+LE L ++G+ + FD+ ADFSG
Sbjct: 301 EQALSARTLRKWSHS--LQKRWIEVFIPRFSISASYNLETILPKMGIQNVFDK-NADFSG 357
Query: 302 MSTEKNVPLSKVAHKCFVEVNEEGTEAAAATA---VVRNSRCSRMEPRFCA---DHPFLF 355
++ ++ +SK HK ++V+EEGTEA AAT +VR S+ P + + FL
Sbjct: 358 IAKRDSLQVSKATHKAVLDVSEEGTEATAATTTKFIVR----SKDGPSYFTVSFNRTFLM 413
Query: 356 FIRHHKTNCILFCGRFSSP 374
I + T+ ILF G+ +P
Sbjct: 414 MITNKATDGILFLGKVENP 432
>gi|10835159 plasminogen activator inhibitor-1 [Homo sapiens]
Length = 402
Score = 182 bits (463), Expect = 3e-46
Identities = 117/370 (31%), Positives = 193/370 (52%), Gaps = 11/370 (2%)
Query: 11 FAISLFKILGEEDNSRNVFFSPMSISSALAMVFMGAKGSTAAQMSQALCL-YKDGDIHRG 69
F + +F+ + + RNV FSP ++S LAM+ + G T Q+ A+ D +
Sbjct: 38 FGVRVFQQVAQASKDRNVVFSPYGVASVLAMLQLTTGGETQQQIQAAMGFKIDDKGMAPA 97
Query: 70 FQSLLSEVNRTGTQYLLRTANRLFGEKTCDFLPDFKEYCQKFYQAELEELSFAEDTEECR 129
+ L E+ + + T + +F ++ + F + + +++ ++++ F+E E R
Sbjct: 98 LRHLYKELMGPWNKDEISTTDAIFVQRDLKLVQGFMPHFFRLFRSTVKQVDFSE-VERAR 156
Query: 130 KHINDWVAEKTEGKISEVLDAGTVDPLTKLVLVNAIYFKGKWNEQFDRKYTRGMLF-KTN 188
INDWV T+G IS +L G VD LT+LVLVNA+YF G+W F T LF K++
Sbjct: 157 FIINDWVKTHTKGMISNLLGKGAVDQLTRLVLVNALYFNGQWKTPFPDSSTHRRLFHKSD 216
Query: 189 EEKKTVQMMFKEAKF---KMGYADEVHTQVLELPYVEEELSMVILLP-DDNTDLAVVEKA 244
+V MM + KF + D + +LELPY + LSM I P + L+ +
Sbjct: 217 GSTVSVPMMAQTNKFNYTEFTTPDGHYYDILELPYHGDTLSMFIAAPYEKEVPLSALTNI 276
Query: 245 LTYEKFKAWTNSEKLTKSKVQVFLPRLKLEESYDLEPFLRRLGMIDAFDEAKADFSGMST 304
L+ + W + +T+ + LP+ LE DL L LGM D F + +ADF+ +S
Sbjct: 277 LSAQLISHWKGN--MTRLPRLLVLPKFSLETEVDLRKPLENLGMTDMFRQFQADFTSLSD 334
Query: 305 EKNVPLSKVAHKCFVEVNEEGTEAAAATAVVRNSRCSRMEPRFCADHPFLFFIRHHKTNC 364
++ + +++ K +EVNE GT A+++TAV+ ++R + E D PFLF +RH+ T
Sbjct: 335 QEPLHVAQALQKVKIEVNESGTVASSSTAVIVSARMAPEE--IIMDRPFLFVVRHNPTGT 392
Query: 365 ILFCGRFSSP 374
+LF G+ P
Sbjct: 393 VLFMGQVMEP 402
>gi|73858566 heparin cofactor II precursor [Homo sapiens]
Length = 499
Score = 181 bits (460), Expect = 7e-46
Identities = 119/378 (31%), Positives = 202/378 (53%), Gaps = 22/378 (5%)
Query: 8 NGTFAISLFKILGEEDNS-RNVFFSPMSISSALAMVFMGAKGSTAAQMSQALCL------ 60
N FA +L+++L ++ N+ N+F +P+ IS+A+ M+ +G KG T Q+ L
Sbjct: 130 NAKFAFNLYRVLKDQVNTFDNIFIAPVGISTAMGMISLGLKGETHEQVHSILHFKDFVNA 189
Query: 61 ---YKDGDIHRGFQSLLSEVNRTGTQYLLRTANRLFGEKTCDFLPDFKEYCQKFYQAELE 117
Y+ IH F+ L + R Y LR+ N L+ +K L DFK +++Y AE +
Sbjct: 190 SSKYEITTIHNLFRKLTHRLFRRNFGYTLRSVNDLYIQKQFPILLDFKTKVREYYFAEAQ 249
Query: 118 ELSFAEDTEECRKHINDWVAEKTEGKISEVLDAGTVDPLTKLVLVNAIYFKGKWNEQFDR 177
F++ + N+ + + T+G I + L+ +DP T+++++N IYFKG W +F
Sbjct: 250 IADFSDPAFISKT--NNHIMKLTKGLIKDALE--NIDPATQMMILNCIYFKGSWVNKFPV 305
Query: 178 KYTRGMLFKTNE-EKKTVQMMFKEAKFKMGYADEVHTQVLELPYVEEELSMVILLPDDNT 236
+ T F+ NE E V MM + F E+ +L+L YV +SM+I++P +
Sbjct: 306 EMTHNHNFRLNEREVVKVSMMQTKGNFLAANDQELDCDILQLEYVGG-ISMLIVVPHKMS 364
Query: 237 DLAVVEKALTYEKFKAWTNSEKLTKSKVQVFLPRLKLEESYDLEPFLRRLGMIDAFDEAK 296
+ +E LT + W S +T +V LP+ KLE++Y+L L+ +G+ FD+
Sbjct: 365 GMKTLEAQLTPRVVERWQKS--MTNRTREVLLPKFKLEKNYNLVESLKLMGIRMLFDK-N 421
Query: 297 ADFSGMSTEKNVPLSKVAHKCFVEVNEEGTEAAAATAVVRNSRCSRMEPRFCADHPFLFF 356
+ +G+S ++ + + H+ + VNEEGT+A T V +++ RF D PFLF
Sbjct: 422 GNMAGISDQR-IAIDLFKHQGTITVNEEGTQATTVTTVGFMPLSTQV--RFTVDRPFLFL 478
Query: 357 IRHHKTNCILFCGRFSSP 374
I H+T+C+LF GR ++P
Sbjct: 479 IYEHRTSCLLFMGRVANP 496
>gi|50659080 serpin peptidase inhibitor, clade A, member 3 precursor
[Homo sapiens]
Length = 423
Score = 177 bits (450), Expect = 1e-44
Identities = 125/379 (32%), Positives = 201/379 (53%), Gaps = 15/379 (3%)
Query: 4 LCEANGTFAISLFKILGEEDNSRNVFFSPMSISSALAMVFMGAKGSTAAQMSQALCLY-- 61
L AN FA SL+K L + +NV FSP+SIS+ALA + +GA +T ++ + L
Sbjct: 49 LASANVDFAFSLYKQLVLKAPDKNVIFSPLSISTALAFLSLGAHNTTLTEILKGLKFNLT 108
Query: 62 --KDGDIHRGFQSLLSEVNRTGTQYLLRTANRLFGEKTCDFLPDFKEYCQKFYQAELEEL 119
+ +IH+ FQ LL +N++ + L N +F ++ L F E ++ Y +E
Sbjct: 109 ETSEAEIHQSFQHLLRTLNQSSDELQLSMGNAMFVKEQLSLLDRFTEDAKRLYGSEAFAT 168
Query: 120 SFAEDTEECRKHINDWVAEKTEGKISEVLDAGTVDPLTKLVLVNAIYFKGKWNEQFDRKY 179
F +D+ +K IND+V T GKI++++ +D T +VLVN I+FK KW FD +
Sbjct: 169 DF-QDSAAAKKLINDYVKNGTRGKITDLIK--DLDSQTMMVLVNYIFFKAKWEMPFDPQD 225
Query: 180 TRGMLFKTNEEKKTVQMMFKEAKFKMGYA--DEVHTQVLELPYVEEELSMVILLPDDNTD 237
T F +++K + M + Y +E+ V+EL Y S + +LPD +
Sbjct: 226 THQSRFYLSKKKWVMVPMMSLHHLTIPYFRDEELSCTVVELKYTGNA-SALFILPDQDK- 283
Query: 238 LAVVEKALTYEKFKAWTNSEKLTKSKVQVFLPRLKLEESYDLEPFLRRLGMIDAFDEAKA 297
+ VE L E K W +S + + +++LP+ + Y+L L +LG+ +AF +KA
Sbjct: 284 MEEVEAMLLPETLKRWRDSLEFREIG-ELYLPKFSISRDYNLNDILLQLGIEEAFT-SKA 341
Query: 298 DFSGMSTEKNVPLSKVAHKCFVEVNEEGTEAAAATAVVRNSRCSRMEPRFCA--DHPFLF 355
D SG++ +N+ +S+V HK ++V EEGTEA+AATAV + +E R + PFL
Sbjct: 342 DLSGITGARNLAVSQVVHKAVLDVFEEGTEASAATAVKITLLSALVETRTIVRFNRPFLM 401
Query: 356 FIRHHKTNCILFCGRFSSP 374
I T I F + ++P
Sbjct: 402 IIVPTDTQNIFFMSKVTNP 420
>gi|189163542 serine proteinase inhibitor, clade A, member 1 [Homo
sapiens]
Length = 418
Score = 177 bits (449), Expect = 1e-44
Identities = 121/369 (32%), Positives = 193/369 (52%), Gaps = 15/369 (4%)
Query: 11 FAISLFKILGEEDNSRNVFFSPMSISSALAMVFMGAKGSTAAQMSQALCL----YKDGDI 66
FA SL++ L + NS N+FFSP+SI++A AM+ +G K T ++ + L + I
Sbjct: 57 FAFSLYRQLAHQSNSTNIFFSPVSIATAFAMLSLGTKADTHDEILEGLNFNLTEIPEAQI 116
Query: 67 HRGFQSLLSEVNRTGTQYLLRTANRLFGEKTCDFLPDFKEYCQKFYQAELEELSFAEDTE 126
H GFQ LL +N+ +Q L T N LF + + F E +K Y +E ++F DTE
Sbjct: 117 HEGFQELLRTLNQPDSQLQLTTGNGLFLSEGLKLVDKFLEDVKKLYHSEAFTVNFG-DTE 175
Query: 127 ECRKHINDWVAEKTEGKISEVLDAGTVDPLTKLVLVNAIYFKGKWNEQFDRKYTRGMLFK 186
E +K IND+V + T+GKI +++ +D T LVN I+FKGKW F+ K T F
Sbjct: 176 EAKKQINDYVEKGTQGKIVDLVK--ELDRDTVFALVNYIFFKGKWERPFEVKDTEEEDFH 233
Query: 187 TNEEKKT-VQMMFKEAKFKMGYADEVHTQVLELPYVEEELSMVILLPDDNTDLAVVEKAL 245
++ V MM + F + + ++ + VL + Y+ + + LPD+ L +E L
Sbjct: 234 VDQVTTVKVPMMKRLGMFNIQHCKKLSSWVLLMKYL-GNATAIFFLPDEG-KLQHLENEL 291
Query: 246 TYEKFKAWTNSEKLTKSKVQVFLPRLKLEESYDLEPFLRRLGMIDAFDEAKADFSGMSTE 305
T++ + +E + + LP+L + +YDL+ L +LG+ F AD SG++ E
Sbjct: 292 THDIITKFLENE--DRRSASLHLPKLSITGTYDLKSVLGQLGITKVFSNG-ADLSGVTEE 348
Query: 306 KNVPLSKVAHKCFVEVNEEGTEAAAATAVVRNSRCSRMEPRFCADHPFLFFIRHHKTNCI 365
+ LSK HK + ++E+GTEAA A + E +F + PF+F + T
Sbjct: 349 APLKLSKAVHKAVLTIDEKGTEAAGAMFLEAIPMSIPPEVKF--NKPFVFLMIEQNTKSP 406
Query: 366 LFCGRFSSP 374
LF G+ +P
Sbjct: 407 LFMGKVVNP 415
>gi|189163540 serine proteinase inhibitor, clade A, member 1 [Homo
sapiens]
Length = 418
Score = 177 bits (449), Expect = 1e-44
Identities = 121/369 (32%), Positives = 193/369 (52%), Gaps = 15/369 (4%)
Query: 11 FAISLFKILGEEDNSRNVFFSPMSISSALAMVFMGAKGSTAAQMSQALCL----YKDGDI 66
FA SL++ L + NS N+FFSP+SI++A AM+ +G K T ++ + L + I
Sbjct: 57 FAFSLYRQLAHQSNSTNIFFSPVSIATAFAMLSLGTKADTHDEILEGLNFNLTEIPEAQI 116
Query: 67 HRGFQSLLSEVNRTGTQYLLRTANRLFGEKTCDFLPDFKEYCQKFYQAELEELSFAEDTE 126
H GFQ LL +N+ +Q L T N LF + + F E +K Y +E ++F DTE
Sbjct: 117 HEGFQELLRTLNQPDSQLQLTTGNGLFLSEGLKLVDKFLEDVKKLYHSEAFTVNFG-DTE 175
Query: 127 ECRKHINDWVAEKTEGKISEVLDAGTVDPLTKLVLVNAIYFKGKWNEQFDRKYTRGMLFK 186
E +K IND+V + T+GKI +++ +D T LVN I+FKGKW F+ K T F
Sbjct: 176 EAKKQINDYVEKGTQGKIVDLVK--ELDRDTVFALVNYIFFKGKWERPFEVKDTEEEDFH 233
Query: 187 TNEEKKT-VQMMFKEAKFKMGYADEVHTQVLELPYVEEELSMVILLPDDNTDLAVVEKAL 245
++ V MM + F + + ++ + VL + Y+ + + LPD+ L +E L
Sbjct: 234 VDQVTTVKVPMMKRLGMFNIQHCKKLSSWVLLMKYL-GNATAIFFLPDEG-KLQHLENEL 291
Query: 246 TYEKFKAWTNSEKLTKSKVQVFLPRLKLEESYDLEPFLRRLGMIDAFDEAKADFSGMSTE 305
T++ + +E + + LP+L + +YDL+ L +LG+ F AD SG++ E
Sbjct: 292 THDIITKFLENE--DRRSASLHLPKLSITGTYDLKSVLGQLGITKVFSNG-ADLSGVTEE 348
Query: 306 KNVPLSKVAHKCFVEVNEEGTEAAAATAVVRNSRCSRMEPRFCADHPFLFFIRHHKTNCI 365
+ LSK HK + ++E+GTEAA A + E +F + PF+F + T
Sbjct: 349 APLKLSKAVHKAVLTIDEKGTEAAGAMFLEAIPMSIPPEVKF--NKPFVFLMIEQNTKSP 406
Query: 366 LFCGRFSSP 374
LF G+ +P
Sbjct: 407 LFMGKVVNP 415
>gi|189163538 serine proteinase inhibitor, clade A, member 1 [Homo
sapiens]
Length = 418
Score = 177 bits (449), Expect = 1e-44
Identities = 121/369 (32%), Positives = 193/369 (52%), Gaps = 15/369 (4%)
Query: 11 FAISLFKILGEEDNSRNVFFSPMSISSALAMVFMGAKGSTAAQMSQALCL----YKDGDI 66
FA SL++ L + NS N+FFSP+SI++A AM+ +G K T ++ + L + I
Sbjct: 57 FAFSLYRQLAHQSNSTNIFFSPVSIATAFAMLSLGTKADTHDEILEGLNFNLTEIPEAQI 116
Query: 67 HRGFQSLLSEVNRTGTQYLLRTANRLFGEKTCDFLPDFKEYCQKFYQAELEELSFAEDTE 126
H GFQ LL +N+ +Q L T N LF + + F E +K Y +E ++F DTE
Sbjct: 117 HEGFQELLRTLNQPDSQLQLTTGNGLFLSEGLKLVDKFLEDVKKLYHSEAFTVNFG-DTE 175
Query: 127 ECRKHINDWVAEKTEGKISEVLDAGTVDPLTKLVLVNAIYFKGKWNEQFDRKYTRGMLFK 186
E +K IND+V + T+GKI +++ +D T LVN I+FKGKW F+ K T F
Sbjct: 176 EAKKQINDYVEKGTQGKIVDLVK--ELDRDTVFALVNYIFFKGKWERPFEVKDTEEEDFH 233
Query: 187 TNEEKKT-VQMMFKEAKFKMGYADEVHTQVLELPYVEEELSMVILLPDDNTDLAVVEKAL 245
++ V MM + F + + ++ + VL + Y+ + + LPD+ L +E L
Sbjct: 234 VDQVTTVKVPMMKRLGMFNIQHCKKLSSWVLLMKYL-GNATAIFFLPDEG-KLQHLENEL 291
Query: 246 TYEKFKAWTNSEKLTKSKVQVFLPRLKLEESYDLEPFLRRLGMIDAFDEAKADFSGMSTE 305
T++ + +E + + LP+L + +YDL+ L +LG+ F AD SG++ E
Sbjct: 292 THDIITKFLENE--DRRSASLHLPKLSITGTYDLKSVLGQLGITKVFSNG-ADLSGVTEE 348
Query: 306 KNVPLSKVAHKCFVEVNEEGTEAAAATAVVRNSRCSRMEPRFCADHPFLFFIRHHKTNCI 365
+ LSK HK + ++E+GTEAA A + E +F + PF+F + T
Sbjct: 349 APLKLSKAVHKAVLTIDEKGTEAAGAMFLEAIPMSIPPEVKF--NKPFVFLMIEQNTKSP 406
Query: 366 LFCGRFSSP 374
LF G+ +P
Sbjct: 407 LFMGKVVNP 415
>gi|189163536 serine proteinase inhibitor, clade A, member 1 [Homo
sapiens]
Length = 418
Score = 177 bits (449), Expect = 1e-44
Identities = 121/369 (32%), Positives = 193/369 (52%), Gaps = 15/369 (4%)
Query: 11 FAISLFKILGEEDNSRNVFFSPMSISSALAMVFMGAKGSTAAQMSQALCL----YKDGDI 66
FA SL++ L + NS N+FFSP+SI++A AM+ +G K T ++ + L + I
Sbjct: 57 FAFSLYRQLAHQSNSTNIFFSPVSIATAFAMLSLGTKADTHDEILEGLNFNLTEIPEAQI 116
Query: 67 HRGFQSLLSEVNRTGTQYLLRTANRLFGEKTCDFLPDFKEYCQKFYQAELEELSFAEDTE 126
H GFQ LL +N+ +Q L T N LF + + F E +K Y +E ++F DTE
Sbjct: 117 HEGFQELLRTLNQPDSQLQLTTGNGLFLSEGLKLVDKFLEDVKKLYHSEAFTVNFG-DTE 175
Query: 127 ECRKHINDWVAEKTEGKISEVLDAGTVDPLTKLVLVNAIYFKGKWNEQFDRKYTRGMLFK 186
E +K IND+V + T+GKI +++ +D T LVN I+FKGKW F+ K T F
Sbjct: 176 EAKKQINDYVEKGTQGKIVDLVK--ELDRDTVFALVNYIFFKGKWERPFEVKDTEEEDFH 233
Query: 187 TNEEKKT-VQMMFKEAKFKMGYADEVHTQVLELPYVEEELSMVILLPDDNTDLAVVEKAL 245
++ V MM + F + + ++ + VL + Y+ + + LPD+ L +E L
Sbjct: 234 VDQVTTVKVPMMKRLGMFNIQHCKKLSSWVLLMKYL-GNATAIFFLPDEG-KLQHLENEL 291
Query: 246 TYEKFKAWTNSEKLTKSKVQVFLPRLKLEESYDLEPFLRRLGMIDAFDEAKADFSGMSTE 305
T++ + +E + + LP+L + +YDL+ L +LG+ F AD SG++ E
Sbjct: 292 THDIITKFLENE--DRRSASLHLPKLSITGTYDLKSVLGQLGITKVFSNG-ADLSGVTEE 348
Query: 306 KNVPLSKVAHKCFVEVNEEGTEAAAATAVVRNSRCSRMEPRFCADHPFLFFIRHHKTNCI 365
+ LSK HK + ++E+GTEAA A + E +F + PF+F + T
Sbjct: 349 APLKLSKAVHKAVLTIDEKGTEAAGAMFLEAIPMSIPPEVKF--NKPFVFLMIEQNTKSP 406
Query: 366 LFCGRFSSP 374
LF G+ +P
Sbjct: 407 LFMGKVVNP 415
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.320 0.134 0.393
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 12,814,859
Number of Sequences: 37866
Number of extensions: 515127
Number of successful extensions: 1648
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 60
Number of HSP's successfully gapped in prelim test: 10
Number of HSP's that attempted gapping in prelim test: 1346
Number of HSP's gapped (non-prelim): 78
length of query: 374
length of database: 18,247,518
effective HSP length: 104
effective length of query: 270
effective length of database: 14,309,454
effective search space: 3863552580
effective search space used: 3863552580
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.