Guide to the Human Genome
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Search of human proteins with 124248516

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|124248516 alpha-defensin 1 [Homo sapiens]
         (94 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|4758146 defensin, alpha 1 preproprotein [Homo sapiens]             194   1e-50
gi|124248516 alpha-defensin 1 [Homo sapiens]                          194   1e-50
gi|4885179 defensin, alpha 3 preproprotein [Homo sapiens]             192   6e-50
gi|4503303 defensin, alpha 4 preproprotein [Homo sapiens]              84   3e-17
gi|10337585 defensin, alpha 5 preproprotein [Homo sapiens]             82   1e-16
gi|4503305 defensin, alpha 6 preproprotein [Homo sapiens]              75   1e-14
gi|169202788 PREDICTED: hypothetical protein [Homo sapiens]            27   2.7  
gi|89034671 PREDICTED: hypothetical protein [Homo sapiens]             27   2.7  
gi|51470873 PREDICTED: hypothetical protein [Homo sapiens]             27   2.7  
gi|111118978 ephrin receptor EphB2 isoform 1 precursor [Homo sap...    27   3.5  
gi|21396504 ephrin receptor EphB2 isoform 2 precursor [Homo sapi...    27   3.5  
gi|210032509 hypothetical protein LOC100130302 [Homo sapiens]          27   4.6  
gi|125625357 Sp2 transcription factor [Homo sapiens]                   26   6.0  

>gi|4758146 defensin, alpha 1 preproprotein [Homo sapiens]
          Length = 94

 Score =  194 bits (493), Expect = 1e-50
 Identities = 94/94 (100%), Positives = 94/94 (100%)

Query: 1  MRTLAILAAILLVALQAQAEPLQARADEVAAAPEQIAADIPEVVVSLAWDESLAPKHPGS 60
          MRTLAILAAILLVALQAQAEPLQARADEVAAAPEQIAADIPEVVVSLAWDESLAPKHPGS
Sbjct: 1  MRTLAILAAILLVALQAQAEPLQARADEVAAAPEQIAADIPEVVVSLAWDESLAPKHPGS 60

Query: 61 RKNMACYCRIPACIAGERRYGTCIYQGRLWAFCC 94
          RKNMACYCRIPACIAGERRYGTCIYQGRLWAFCC
Sbjct: 61 RKNMACYCRIPACIAGERRYGTCIYQGRLWAFCC 94


>gi|124248516 alpha-defensin 1 [Homo sapiens]
          Length = 94

 Score =  194 bits (493), Expect = 1e-50
 Identities = 94/94 (100%), Positives = 94/94 (100%)

Query: 1  MRTLAILAAILLVALQAQAEPLQARADEVAAAPEQIAADIPEVVVSLAWDESLAPKHPGS 60
          MRTLAILAAILLVALQAQAEPLQARADEVAAAPEQIAADIPEVVVSLAWDESLAPKHPGS
Sbjct: 1  MRTLAILAAILLVALQAQAEPLQARADEVAAAPEQIAADIPEVVVSLAWDESLAPKHPGS 60

Query: 61 RKNMACYCRIPACIAGERRYGTCIYQGRLWAFCC 94
          RKNMACYCRIPACIAGERRYGTCIYQGRLWAFCC
Sbjct: 61 RKNMACYCRIPACIAGERRYGTCIYQGRLWAFCC 94


>gi|4885179 defensin, alpha 3 preproprotein [Homo sapiens]
          Length = 94

 Score =  192 bits (487), Expect = 6e-50
 Identities = 93/94 (98%), Positives = 93/94 (98%)

Query: 1  MRTLAILAAILLVALQAQAEPLQARADEVAAAPEQIAADIPEVVVSLAWDESLAPKHPGS 60
          MRTLAILAAILLVALQAQAEPLQARADEVAAAPEQIAADIPEVVVSLAWDESLAPKHPGS
Sbjct: 1  MRTLAILAAILLVALQAQAEPLQARADEVAAAPEQIAADIPEVVVSLAWDESLAPKHPGS 60

Query: 61 RKNMACYCRIPACIAGERRYGTCIYQGRLWAFCC 94
          RKNM CYCRIPACIAGERRYGTCIYQGRLWAFCC
Sbjct: 61 RKNMDCYCRIPACIAGERRYGTCIYQGRLWAFCC 94


>gi|4503303 defensin, alpha 4 preproprotein [Homo sapiens]
          Length = 97

 Score = 83.6 bits (205), Expect = 3e-17
 Identities = 44/94 (46%), Positives = 58/94 (61%), Gaps = 1/94 (1%)

Query: 1  MRTLAILAAILLVALQAQAEPLQARADEVAAAPEQIAADIPEVVVSLAWDESLAPKHPGS 60
          MR +A+LAAILLVALQ +A PLQAR DE A   EQ   +  ++ +S AWD+S A +  GS
Sbjct: 1  MRIIALLAAILLVALQVRAGPLQARGDE-APGQEQRGPEDQDISISFAWDKSSALQVSGS 59

Query: 61 RKNMACYCRIPACIAGERRYGTCIYQGRLWAFCC 94
           + M C CR+  C   E R G C+  G  + +CC
Sbjct: 60 TRGMVCSCRLVFCRRTELRVGNCLIGGVSFTYCC 93


>gi|10337585 defensin, alpha 5 preproprotein [Homo sapiens]
          Length = 94

 Score = 81.6 bits (200), Expect = 1e-16
 Identities = 46/94 (48%), Positives = 55/94 (58%), Gaps = 1/94 (1%)

Query: 1  MRTLAILAAILLVALQAQAEPLQARADEVAAAPEQIAADIPEVVVSLAWDESLAPKHPGS 60
          MRT+AILAAILLVALQAQAE LQ RADE A   +Q   D  ++ +S A +   A +  GS
Sbjct: 1  MRTIAILAAILLVALQAQAESLQERADE-ATTQKQSGEDNQDLAISFAGNGLSALRTSGS 59

Query: 61 RKNMACYCRIPACIAGERRYGTCIYQGRLWAFCC 94
          +    CYCR   C   E   G C   GRL+  CC
Sbjct: 60 QARATCYCRTGRCATRESLSGVCEISGRLYRLCC 93


>gi|4503305 defensin, alpha 6 preproprotein [Homo sapiens]
          Length = 100

 Score = 74.7 bits (182), Expect = 1e-14
 Identities = 46/100 (46%), Positives = 57/100 (57%), Gaps = 7/100 (7%)

Query: 1  MRTLAILAAILLVALQAQAEPLQARADEVAA------APEQIAADIPEVVVSLAWDESLA 54
          MRTL IL A+LLVALQA+AEPLQA  D + A      A EQ  A+  +  VS A D S +
Sbjct: 1  MRTLTILTAVLLVALQAKAEPLQAEDDPLQAKAYEADAQEQRGANDQDFAVSFAEDASSS 60

Query: 55 PKHPGSRKNMACYCRIPACIAGERRYGTCIYQGRLWAFCC 94
           +  GS +   C+CR  +C + E  YGTC   G    FCC
Sbjct: 61 LRALGSTRAFTCHCR-RSCYSTEYSYGTCTVMGINHRFCC 99


>gi|169202788 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 224

 Score = 27.3 bits (59), Expect = 2.7
 Identities = 15/56 (26%), Positives = 23/56 (41%), Gaps = 14/56 (25%)

Query: 39  DIPEVVVSLAW--------------DESLAPKHPGSRKNMACYCRIPACIAGERRY 80
           + PEV+  L W              DE LA  HPG R  +     +P+ + G  ++
Sbjct: 86  EAPEVMFELLWAGLELDVMGQLHIQDEELASTHPGRRLRLLLQHHVPSDLEGTEQW 141


>gi|89034671 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 224

 Score = 27.3 bits (59), Expect = 2.7
 Identities = 15/56 (26%), Positives = 23/56 (41%), Gaps = 14/56 (25%)

Query: 39  DIPEVVVSLAW--------------DESLAPKHPGSRKNMACYCRIPACIAGERRY 80
           + PEV+  L W              DE LA  HPG R  +     +P+ + G  ++
Sbjct: 86  EAPEVMFELLWAGLELDVMGQLHIQDEELASTHPGRRLRLLLQHHVPSDLEGTEQW 141


>gi|51470873 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 224

 Score = 27.3 bits (59), Expect = 2.7
 Identities = 15/56 (26%), Positives = 23/56 (41%), Gaps = 14/56 (25%)

Query: 39  DIPEVVVSLAW--------------DESLAPKHPGSRKNMACYCRIPACIAGERRY 80
           + PEV+  L W              DE LA  HPG R  +     +P+ + G  ++
Sbjct: 86  EAPEVMFELLWAGLELDVMGQLHIQDEELASTHPGRRLRLLLQHHVPSDLEGTEQW 141


>gi|111118978 ephrin receptor EphB2 isoform 1 precursor [Homo
           sapiens]
          Length = 986

 Score = 26.9 bits (58), Expect = 3.5
 Identities = 15/68 (22%), Positives = 30/68 (44%), Gaps = 6/68 (8%)

Query: 16  QAQAEPLQARADEVAAAPEQIAADIPEVVVSLAWDESLAPKHPGSRKNMACYCRIPACIA 75
           +A  +PL      + +AP+ + + + E  + L W     P+  G R+++       +C +
Sbjct: 311 RADLDPLDMPCTTIPSAPQAVISSVNETSLMLEW---TPPRDSGGREDLVYNIICKSCGS 367

Query: 76  GERRYGTC 83
           G    G C
Sbjct: 368 GR---GAC 372


>gi|21396504 ephrin receptor EphB2 isoform 2 precursor [Homo
           sapiens]
          Length = 987

 Score = 26.9 bits (58), Expect = 3.5
 Identities = 15/68 (22%), Positives = 30/68 (44%), Gaps = 6/68 (8%)

Query: 16  QAQAEPLQARADEVAAAPEQIAADIPEVVVSLAWDESLAPKHPGSRKNMACYCRIPACIA 75
           +A  +PL      + +AP+ + + + E  + L W     P+  G R+++       +C +
Sbjct: 311 RADLDPLDMPCTTIPSAPQAVISSVNETSLMLEW---TPPRDSGGREDLVYNIICKSCGS 367

Query: 76  GERRYGTC 83
           G    G C
Sbjct: 368 GR---GAC 372


>gi|210032509 hypothetical protein LOC100130302 [Homo sapiens]
          Length = 887

 Score = 26.6 bits (57), Expect = 4.6
 Identities = 21/51 (41%), Positives = 22/51 (43%), Gaps = 4/51 (7%)

Query: 7   LAAILLVALQAQAEPLQARADEVAAAPEQIAADIPEVVVSLAWDESLAPKH 57
           LAA    AL A A P  A     AAAP    A  P V  + A   S AP H
Sbjct: 522 LAAAAAPALAAAAAPALA----AAAAPAPAPAAAPAVAAAPAAAASAAPSH 568


>gi|125625357 Sp2 transcription factor [Homo sapiens]
          Length = 613

 Score = 26.2 bits (56), Expect = 6.0
 Identities = 16/39 (41%), Positives = 23/39 (58%), Gaps = 4/39 (10%)

Query: 45  VSLAWDESLAPK-HPGS-RKNMACYCRIPACIAGERRYG 81
           + L  +++LA +  PG  R+ MAC C  P C  GE+R G
Sbjct: 482 IQLQMEQALAGETQPGEKRRRMACTC--PNCKDGEKRSG 518


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.326    0.135    0.434 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 3,548,336
Number of Sequences: 37866
Number of extensions: 134188
Number of successful extensions: 448
Number of sequences better than 10.0: 13
Number of HSP's better than 10.0 without gapping: 6
Number of HSP's successfully gapped in prelim test: 7
Number of HSP's that attempted gapping in prelim test: 437
Number of HSP's gapped (non-prelim): 13
length of query: 94
length of database: 18,247,518
effective HSP length: 65
effective length of query: 29
effective length of database: 15,786,228
effective search space: 457800612
effective search space used: 457800612
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.7 bits)
S2: 55 (25.8 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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