Guide to the Human Genome
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Search of human proteins with 12408668

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|12408668 phosducin isoform b [Homo sapiens]
         (194 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|32967591 phosducin isoform a [Homo sapiens]                        391   e-109
gi|12408668 phosducin isoform b [Homo sapiens]                        391   e-109
gi|88758594 phosducin-like [Homo sapiens]                             197   6e-51
gi|13129044 phosducin-like 3 [Homo sapiens]                            61   5e-10
gi|51944950 phosducin-like 2 [Homo sapiens]                            60   2e-09
gi|95113651 glutaredoxin 3 [Homo sapiens]                              39   0.002
gi|18104959 thioredoxin domain containing 9 [Homo sapiens]             38   0.005
gi|38348344 hypothetical protein LOC374355 [Homo sapiens]              32   0.34 
gi|208610002 atlastin GTPase 2 isoform 2 [Homo sapiens]                30   1.3  
gi|208610000 atlastin GTPase 2 isoform 1 [Homo sapiens]                30   1.3  
gi|20270307 coiled-coil domain containing 74A [Homo sapiens]           30   1.7  
gi|21361403 thioredoxin 2 precursor [Homo sapiens]                     28   3.7  
gi|46409266 coiled-coil domain containing 74B [Homo sapiens]           28   6.4  
gi|171906589 branched chain ketoacid dehydrogenase kinase isofor...    27   8.4  

>gi|32967591 phosducin isoform a [Homo sapiens]
          Length = 246

 Score =  391 bits (1004), Expect = e-109
 Identities = 194/194 (100%), Positives = 194/194 (100%)

Query: 1   MSSPQSRNGKDSKERVSRKMSIQEYELIHKEKEDENCLRKYRRQCMQDMHQKLSFGPRYG 60
           MSSPQSRNGKDSKERVSRKMSIQEYELIHKEKEDENCLRKYRRQCMQDMHQKLSFGPRYG
Sbjct: 53  MSSPQSRNGKDSKERVSRKMSIQEYELIHKEKEDENCLRKYRRQCMQDMHQKLSFGPRYG 112

Query: 61  FVYELETGKQFLETIEKELKITTIVVHIYEDGIKGCDALNSSLTCLAAEYPIVKFCKIKA 120
           FVYELETGKQFLETIEKELKITTIVVHIYEDGIKGCDALNSSLTCLAAEYPIVKFCKIKA
Sbjct: 113 FVYELETGKQFLETIEKELKITTIVVHIYEDGIKGCDALNSSLTCLAAEYPIVKFCKIKA 172

Query: 121 SNTGAGDRFSLDVLPTLLIYKGGELISNFISVAEQFAEEFFAGDVESFLNEYGLLPEREV 180
           SNTGAGDRFSLDVLPTLLIYKGGELISNFISVAEQFAEEFFAGDVESFLNEYGLLPEREV
Sbjct: 173 SNTGAGDRFSLDVLPTLLIYKGGELISNFISVAEQFAEEFFAGDVESFLNEYGLLPEREV 232

Query: 181 HVLEHTKIEEEDVE 194
           HVLEHTKIEEEDVE
Sbjct: 233 HVLEHTKIEEEDVE 246


>gi|12408668 phosducin isoform b [Homo sapiens]
          Length = 194

 Score =  391 bits (1004), Expect = e-109
 Identities = 194/194 (100%), Positives = 194/194 (100%)

Query: 1   MSSPQSRNGKDSKERVSRKMSIQEYELIHKEKEDENCLRKYRRQCMQDMHQKLSFGPRYG 60
           MSSPQSRNGKDSKERVSRKMSIQEYELIHKEKEDENCLRKYRRQCMQDMHQKLSFGPRYG
Sbjct: 1   MSSPQSRNGKDSKERVSRKMSIQEYELIHKEKEDENCLRKYRRQCMQDMHQKLSFGPRYG 60

Query: 61  FVYELETGKQFLETIEKELKITTIVVHIYEDGIKGCDALNSSLTCLAAEYPIVKFCKIKA 120
           FVYELETGKQFLETIEKELKITTIVVHIYEDGIKGCDALNSSLTCLAAEYPIVKFCKIKA
Sbjct: 61  FVYELETGKQFLETIEKELKITTIVVHIYEDGIKGCDALNSSLTCLAAEYPIVKFCKIKA 120

Query: 121 SNTGAGDRFSLDVLPTLLIYKGGELISNFISVAEQFAEEFFAGDVESFLNEYGLLPEREV 180
           SNTGAGDRFSLDVLPTLLIYKGGELISNFISVAEQFAEEFFAGDVESFLNEYGLLPEREV
Sbjct: 121 SNTGAGDRFSLDVLPTLLIYKGGELISNFISVAEQFAEEFFAGDVESFLNEYGLLPEREV 180

Query: 181 HVLEHTKIEEEDVE 194
           HVLEHTKIEEEDVE
Sbjct: 181 HVLEHTKIEEEDVE 194


>gi|88758594 phosducin-like [Homo sapiens]
          Length = 301

 Score =  197 bits (500), Expect = 6e-51
 Identities = 90/179 (50%), Positives = 137/179 (76%)

Query: 5   QSRNGKDSKERVSRKMSIQEYELIHKEKEDENCLRKYRRQCMQDMHQKLSFGPRYGFVYE 64
           + +  KD +E++S KM+++E+ +++++++DE  L++YR+Q M++M Q+L  GP++  V+E
Sbjct: 104 EQQKQKDLQEKISGKMTLKEFAIMNEDQDDEEFLQQYRKQRMEEMRQQLHKGPQFKQVFE 163

Query: 65  LETGKQFLETIEKELKITTIVVHIYEDGIKGCDALNSSLTCLAAEYPIVKFCKIKASNTG 124
           + +G+ FL+ I+KE K   I+VHIYEDGI G +A+N  + CLAAEYP VKFCK+K+S  G
Sbjct: 164 ISSGEGFLDMIDKEQKSIVIMVHIYEDGIPGTEAMNGCMICLAAEYPAVKFCKVKSSVIG 223

Query: 125 AGDRFSLDVLPTLLIYKGGELISNFISVAEQFAEEFFAGDVESFLNEYGLLPEREVHVL 183
           A  +F+ + LP LLIYKGGELI NF+ V +Q  ++FFA D+E+FL E+GLLPE+EV VL
Sbjct: 224 ASSQFTRNALPALLIYKGGELIGNFVRVTDQLGDDFFAVDLEAFLQEFGLLPEKEVLVL 282


>gi|13129044 phosducin-like 3 [Homo sapiens]
          Length = 239

 Score = 61.2 bits (147), Expect = 5e-10
 Identities = 40/133 (30%), Positives = 74/133 (55%), Gaps = 6/133 (4%)

Query: 20  MSIQEYELIHKE--KEDENCLRKYRRQCMQDMHQKLSFGPRYGFVYELETGKQFLETIEK 77
           M+++E E    E  +EDE  +  YRR+ + +  +      ++G V E+ +GK +++ + K
Sbjct: 51  MTLEELEDHEDEFNEEDERAIEMYRRRRLAEW-KATKLKNKFGEVLEI-SGKDYVQEVTK 108

Query: 78  ELKITTIVVHIYEDGIKGCDALNSSLTCLAAEYPIVKFCKIKASNTGAGDRFSLDVLPTL 137
             +   +++H+Y+ GI  C  +N  L+ LA ++P VKF  IKA +T     +    LPT+
Sbjct: 109 AGEGLWVILHLYKQGIPLCALINQHLSGLARKFPDVKF--IKAISTTCIPNYPDRNLPTI 166

Query: 138 LIYKGGELISNFI 150
            +Y  G++ + FI
Sbjct: 167 FVYLEGDIKAQFI 179


>gi|51944950 phosducin-like 2 [Homo sapiens]
          Length = 241

 Score = 59.7 bits (143), Expect = 2e-09
 Identities = 36/147 (24%), Positives = 76/147 (51%), Gaps = 6/147 (4%)

Query: 10  KDSKERVSRKMSIQEYELIHKE--KEDENCLRKYRRQCMQDMHQKLSFGPRYGFVYELET 67
           K++  +   KM++ + +    E  +ED   +  YR++ +Q+  + L    ++G + E+ +
Sbjct: 39  KEAMVKPFEKMTLAQLKEAEDEFDEEDMQAVETYRKKRLQEW-KALKKKQKFGELREI-S 96

Query: 68  GKQFLETIEKELKITTIVVHIYEDGIKGCDALNSSLTCLAAEYPIVKFCKIKASNTGAGD 127
           G Q++  +    +   +++H+Y   I  C  +N  L+ LA ++P  KF  +KA       
Sbjct: 97  GNQYVNEVTNAEEDVWVIIHLYRSSIPMCLLVNQHLSLLARKFPETKF--VKAIVNSCIQ 154

Query: 128 RFSLDVLPTLLIYKGGELISNFISVAE 154
            +  + LPT+ +YK G++ + FI + E
Sbjct: 155 HYHDNCLPTIFVYKNGQIEAKFIGIIE 181


>gi|95113651 glutaredoxin 3 [Homo sapiens]
          Length = 335

 Score = 39.3 bits (90), Expect = 0.002
 Identities = 24/86 (27%), Positives = 42/86 (48%), Gaps = 2/86 (2%)

Query: 62  VYELETGKQFLETIEKELKITTIVVHIYEDGIKGCDALNSSLTCLAAEYPIVKFCKIKAS 121
           V E+ +  QF E +  + K + +VVH +      C  +N  +  LA E P V F K++A 
Sbjct: 13  VEEVGSAGQFEELLRLKAK-SLLVVHFWAPWAPQCAQMNEVMAELAKELPQVSFVKLEAE 71

Query: 122 NT-GAGDRFSLDVLPTLLIYKGGELI 146
                 +++ +  +PT L +K  + I
Sbjct: 72  GVPEVSEKYEISSVPTFLFFKNSQKI 97


>gi|18104959 thioredoxin domain containing 9 [Homo sapiens]
          Length = 226

 Score = 38.1 bits (87), Expect = 0.005
 Identities = 26/103 (25%), Positives = 47/103 (45%), Gaps = 6/103 (5%)

Query: 43  RQCMQDMHQKLSFGPRYGFVYELETGKQFLETIEKELKITTIVVHIYEDGIKGCDALNSS 102
           R+  Q   + LS G  +G   E+ + + F + +++      +V H Y D    C  L+  
Sbjct: 56  RKAQQQKQEWLSKG--HGEYREIPSERDFFQEVKES---ENVVCHFYRDSTFRCKILDRH 110

Query: 103 LTCLAAEYPIVKFCKIKASNTG-AGDRFSLDVLPTLLIYKGGE 144
           L  L+ ++   KF K+         +R  + V+PTL + K G+
Sbjct: 111 LAILSKKHLETKFLKLNVEKAPFLCERLHIKVIPTLALLKDGK 153


>gi|38348344 hypothetical protein LOC374355 [Homo sapiens]
          Length = 258

 Score = 32.0 bits (71), Expect = 0.34
 Identities = 17/52 (32%), Positives = 30/52 (57%), Gaps = 2/52 (3%)

Query: 145 LISNFISVAEQFAEEF--FAGDVESFLNEYGLLPEREVHVLEHTKIEEEDVE 194
           L+  F ++ +Q  EE   F  ++  F N+Y +  +RE+ + E+ KIE  D+E
Sbjct: 90  LLQTFEAIKKQMIEEEDKFIKEITDFNNDYEITKKRELLMKENVKIEISDLE 141


>gi|208610002 atlastin GTPase 2 isoform 2 [Homo sapiens]
          Length = 583

 Score = 30.0 bits (66), Expect = 1.3
 Identities = 32/107 (29%), Positives = 47/107 (43%), Gaps = 16/107 (14%)

Query: 21  SIQEYELIHKEKEDE----NCLRKYRRQCMQDMHQK----LSFGPR-----YGFVYELET 67
           S+Q Y L    +ED+        +Y R  M++++QK    L F  R     Y   Y LE 
Sbjct: 199 SVQVYNLSQNIQEDDLQHLQLFTEYGRLAMEEIYQKPFQTLMFLIRDWSYPYEHSYGLEG 258

Query: 68  GKQFLETIEKELKITTIVVHIYEDGIKGCDALNSSLTCLAAEYPIVK 114
           GKQFL   EK L++        ++  K      S+L C    +P +K
Sbjct: 259 GKQFL---EKRLQVKQNQHEELQNVRKHIHNCFSNLGCFLLPHPGLK 302


>gi|208610000 atlastin GTPase 2 isoform 1 [Homo sapiens]
          Length = 579

 Score = 30.0 bits (66), Expect = 1.3
 Identities = 32/107 (29%), Positives = 47/107 (43%), Gaps = 16/107 (14%)

Query: 21  SIQEYELIHKEKEDE----NCLRKYRRQCMQDMHQK----LSFGPR-----YGFVYELET 67
           S+Q Y L    +ED+        +Y R  M++++QK    L F  R     Y   Y LE 
Sbjct: 199 SVQVYNLSQNIQEDDLQHLQLFTEYGRLAMEEIYQKPFQTLMFLIRDWSYPYEHSYGLEG 258

Query: 68  GKQFLETIEKELKITTIVVHIYEDGIKGCDALNSSLTCLAAEYPIVK 114
           GKQFL   EK L++        ++  K      S+L C    +P +K
Sbjct: 259 GKQFL---EKRLQVKQNQHEELQNVRKHIHNCFSNLGCFLLPHPGLK 302


>gi|20270307 coiled-coil domain containing 74A [Homo sapiens]
          Length = 378

 Score = 29.6 bits (65), Expect = 1.7
 Identities = 14/32 (43%), Positives = 20/32 (62%)

Query: 4   PQSRNGKDSKERVSRKMSIQEYELIHKEKEDE 35
           P S N +DSK  VS+K  ++E  L+H  K D+
Sbjct: 188 PGSFNKQDSKADVSQKADLEEEPLLHNSKLDK 219


>gi|21361403 thioredoxin 2 precursor [Homo sapiens]
          Length = 166

 Score = 28.5 bits (62), Expect = 3.7
 Identities = 20/101 (19%), Positives = 43/101 (42%), Gaps = 4/101 (3%)

Query: 63  YELETGKQFLETIEKELKITTIVVHIYEDGIKGCDALNSSLTCLAA-EYPIVKFCKIKAS 121
           + ++ G  F + +      T +VV  +      C  L   L  + A ++  V   K+   
Sbjct: 62  FNIQDGPDFQDRVVNSE--TPVVVDFHAQWCGPCKILGPRLEKMVAKQHGKVVMAKVDID 119

Query: 122 N-TGAGDRFSLDVLPTLLIYKGGELISNFISVAEQFAEEFF 161
           + T     + +  +PT+L  K G+++  F+ + ++   E F
Sbjct: 120 DHTDLAIEYEVSAVPTVLAMKNGDVVDKFVGIKDEDQLEAF 160


>gi|46409266 coiled-coil domain containing 74B [Homo sapiens]
          Length = 380

 Score = 27.7 bits (60), Expect = 6.4
 Identities = 13/32 (40%), Positives = 19/32 (59%)

Query: 4   PQSRNGKDSKERVSRKMSIQEYELIHKEKEDE 35
           P S N +DSK  V +K  ++E  L+H  K D+
Sbjct: 188 PGSFNKQDSKADVPQKADLEEEPLLHNSKLDK 219


>gi|171906589 branched chain ketoacid dehydrogenase kinase isoform a
           [Homo sapiens]
          Length = 412

 Score = 27.3 bits (59), Expect = 8.4
 Identities = 11/37 (29%), Positives = 20/37 (54%)

Query: 48  DMHQKLSFGPRYGFVYELETGKQFLETIEKELKITTI 84
           DMH     GP +GF + L T + + E +   L++ ++
Sbjct: 353 DMHSGAQSGPMHGFGFGLPTSRAYAEYLGGSLQLQSL 389


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.317    0.136    0.384 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 7,361,631
Number of Sequences: 37866
Number of extensions: 308465
Number of successful extensions: 846
Number of sequences better than 10.0: 14
Number of HSP's better than 10.0 without gapping: 9
Number of HSP's successfully gapped in prelim test: 5
Number of HSP's that attempted gapping in prelim test: 835
Number of HSP's gapped (non-prelim): 14
length of query: 194
length of database: 18,247,518
effective HSP length: 97
effective length of query: 97
effective length of database: 14,574,516
effective search space: 1413728052
effective search space used: 1413728052
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 59 (27.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
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