Guide to the Human Genome
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Search of human proteins with 38455410

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|38455410 growth hormone secretagogue receptor isoform 1a
[Homo sapiens]
         (366 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|38455410 growth hormone secretagogue receptor isoform 1a [Hom...   738   0.0  
gi|4758434 growth hormone secretagogue receptor isoform 1b [Homo...   539   e-153
gi|4504095 motilin receptor [Homo sapiens]                            322   3e-88
gi|110611243 neurotensin receptor 1 [Homo sapiens]                    173   2e-43
gi|170932505 neuromedin U receptor 2 [Homo sapiens]                   168   6e-42
gi|188497623 neuromedin U receptor 1 [Homo sapiens]                   167   1e-41
gi|39725940 opioid receptor, kappa 1 [Homo sapiens]                   140   1e-33
gi|4505513 opiate receptor-like 1 [Homo sapiens]                      132   6e-31
gi|33286424 opiate receptor-like 1 [Homo sapiens]                     132   6e-31
gi|223718055 opioid receptor, mu 1 isoform MOR-1H [Homo sapiens]      130   2e-30
gi|117940060 opioid receptor, mu 1 isoform MOR-1 [Homo sapiens]       130   2e-30
gi|223718712 opioid receptor, mu 1 isoform MOR-1B5 [Homo sapiens]     130   2e-30
gi|223718719 opioid receptor, mu 1 isoform MOR-1B2 [Homo sapiens]     130   2e-30
gi|223718077 opioid receptor, mu 1 isoform MOR-1B3 [Homo sapiens]     130   2e-30
gi|223718716 opioid receptor, mu 1 isoform MOR-1B1 [Homo sapiens]     130   2e-30
gi|117940058 opioid receptor, mu 1 isoform MOR-1A [Homo sapiens]      130   2e-30
gi|223717969 opioid receptor, mu 1 isoform MOR-1B4 [Homo sapiens]     130   2e-30
gi|117940055 opioid receptor, mu 1 isoform MOR-1O [Homo sapiens]      130   2e-30
gi|117940054 opioid receptor, mu 1 isoform MOR-1X [Homo sapiens]      130   2e-30
gi|157738685 G protein-coupled receptor 103 [Homo sapiens]            126   3e-29
gi|63477962 opioid receptor, delta 1 [Homo sapiens]                   124   1e-28
gi|149944554 somatostatin receptor 4 [Homo sapiens]                   124   2e-28
gi|4507681 thyrotropin-releasing hormone receptor [Homo sapiens]      124   2e-28
gi|4503905 galanin receptor 2 [Homo sapiens]                          122   7e-28
gi|4557859 somatostatin receptor 2 [Homo sapiens]                     117   2e-26
gi|4557865 somatostatin receptor 5 [Homo sapiens]                     116   4e-26
gi|4557857 somatostatin receptor 1 [Homo sapiens]                     114   1e-25
gi|4503465 endothelin receptor type A [Homo sapiens]                  113   3e-25
gi|157426873 tachykinin receptor 2 [Homo sapiens]                     113   3e-25
gi|223718066 opioid receptor, mu 1 isoform MOR-1G2 [Homo sapiens]     109   4e-24

>gi|38455410 growth hormone secretagogue receptor isoform 1a [Homo
           sapiens]
          Length = 366

 Score =  738 bits (1905), Expect = 0.0
 Identities = 366/366 (100%), Positives = 366/366 (100%)

Query: 1   MWNATPSEEPGFNLTLADLDWDASPGNDSLGDELLQLFPAPLLAGVTATCVALFVVGIAG 60
           MWNATPSEEPGFNLTLADLDWDASPGNDSLGDELLQLFPAPLLAGVTATCVALFVVGIAG
Sbjct: 1   MWNATPSEEPGFNLTLADLDWDASPGNDSLGDELLQLFPAPLLAGVTATCVALFVVGIAG 60

Query: 61  NLLTMLVVSRFRELRTTTNLYLSSMAFSDLLIFLCMPLDLVRLWQYRPWNFGDLLCKLFQ 120
           NLLTMLVVSRFRELRTTTNLYLSSMAFSDLLIFLCMPLDLVRLWQYRPWNFGDLLCKLFQ
Sbjct: 61  NLLTMLVVSRFRELRTTTNLYLSSMAFSDLLIFLCMPLDLVRLWQYRPWNFGDLLCKLFQ 120

Query: 121 FVSESCTYATVLTITALSVERYFAICFPLRAKVVVTKGRVKLVIFVIWAVAFCSAGPIFV 180
           FVSESCTYATVLTITALSVERYFAICFPLRAKVVVTKGRVKLVIFVIWAVAFCSAGPIFV
Sbjct: 121 FVSESCTYATVLTITALSVERYFAICFPLRAKVVVTKGRVKLVIFVIWAVAFCSAGPIFV 180

Query: 181 LVGVEHENGTDPWDTNECRPTEFAVRSGLLTVMVWVSSIFFFLPVFCLTVLYSLIGRKLW 240
           LVGVEHENGTDPWDTNECRPTEFAVRSGLLTVMVWVSSIFFFLPVFCLTVLYSLIGRKLW
Sbjct: 181 LVGVEHENGTDPWDTNECRPTEFAVRSGLLTVMVWVSSIFFFLPVFCLTVLYSLIGRKLW 240

Query: 241 RRRRGDAVVGASLRDQNHKQTVKMLAVVVFAFILCWLPFHVGRYLFSKSFEPGSLEIAQI 300
           RRRRGDAVVGASLRDQNHKQTVKMLAVVVFAFILCWLPFHVGRYLFSKSFEPGSLEIAQI
Sbjct: 241 RRRRGDAVVGASLRDQNHKQTVKMLAVVVFAFILCWLPFHVGRYLFSKSFEPGSLEIAQI 300

Query: 301 SQYCNLVSFVLFYLSAAINPILYNIMSKKYRVAVFRLLGFEPFSQRKLSTLKDESSRAWT 360
           SQYCNLVSFVLFYLSAAINPILYNIMSKKYRVAVFRLLGFEPFSQRKLSTLKDESSRAWT
Sbjct: 301 SQYCNLVSFVLFYLSAAINPILYNIMSKKYRVAVFRLLGFEPFSQRKLSTLKDESSRAWT 360

Query: 361 ESSINT 366
           ESSINT
Sbjct: 361 ESSINT 366


>gi|4758434 growth hormone secretagogue receptor isoform 1b [Homo
           sapiens]
          Length = 289

 Score =  539 bits (1388), Expect = e-153
 Identities = 265/265 (100%), Positives = 265/265 (100%)

Query: 1   MWNATPSEEPGFNLTLADLDWDASPGNDSLGDELLQLFPAPLLAGVTATCVALFVVGIAG 60
           MWNATPSEEPGFNLTLADLDWDASPGNDSLGDELLQLFPAPLLAGVTATCVALFVVGIAG
Sbjct: 1   MWNATPSEEPGFNLTLADLDWDASPGNDSLGDELLQLFPAPLLAGVTATCVALFVVGIAG 60

Query: 61  NLLTMLVVSRFRELRTTTNLYLSSMAFSDLLIFLCMPLDLVRLWQYRPWNFGDLLCKLFQ 120
           NLLTMLVVSRFRELRTTTNLYLSSMAFSDLLIFLCMPLDLVRLWQYRPWNFGDLLCKLFQ
Sbjct: 61  NLLTMLVVSRFRELRTTTNLYLSSMAFSDLLIFLCMPLDLVRLWQYRPWNFGDLLCKLFQ 120

Query: 121 FVSESCTYATVLTITALSVERYFAICFPLRAKVVVTKGRVKLVIFVIWAVAFCSAGPIFV 180
           FVSESCTYATVLTITALSVERYFAICFPLRAKVVVTKGRVKLVIFVIWAVAFCSAGPIFV
Sbjct: 121 FVSESCTYATVLTITALSVERYFAICFPLRAKVVVTKGRVKLVIFVIWAVAFCSAGPIFV 180

Query: 181 LVGVEHENGTDPWDTNECRPTEFAVRSGLLTVMVWVSSIFFFLPVFCLTVLYSLIGRKLW 240
           LVGVEHENGTDPWDTNECRPTEFAVRSGLLTVMVWVSSIFFFLPVFCLTVLYSLIGRKLW
Sbjct: 181 LVGVEHENGTDPWDTNECRPTEFAVRSGLLTVMVWVSSIFFFLPVFCLTVLYSLIGRKLW 240

Query: 241 RRRRGDAVVGASLRDQNHKQTVKML 265
           RRRRGDAVVGASLRDQNHKQTVKML
Sbjct: 241 RRRRGDAVVGASLRDQNHKQTVKML 265


>gi|4504095 motilin receptor [Homo sapiens]
          Length = 412

 Score =  322 bits (825), Expect = 3e-88
 Identities = 176/360 (48%), Positives = 229/360 (63%), Gaps = 50/360 (13%)

Query: 21  WDASPGNDSLGDELLQLFPAPLLAGVTATCVALFVVGIAGNLLTMLVVSRFRELRTTTNL 80
           W A P  D   +     FP   L  VTA C+ LFVVG++GN++T++++ R+R++RTTTNL
Sbjct: 19  WPALPPCD---ERRCSPFPLGALVPVTAVCLCLFVVGVSGNVVTVMLIGRYRDMRTTTNL 75

Query: 81  YLSSMAFSDLLIFLCMPLDLVRLWQYRPWNFGDLLCKLFQFVSESCTYATVLTITALSVE 140
           YL SMA SDLLI L +P DL RLW+ RPW FG LLC+L  +V E CTYAT+L +TALSVE
Sbjct: 76  YLGSMAVSDLLILLGLPFDLYRLWRSRPWVFGPLLCRLSLYVGEGCTYATLLHMTALSVE 135

Query: 141 RYFAICFPLRAKVVVTKGRVKLVIFVIWAVAFCSAGPIFVLVGVEHE---------NGT- 190
           RY AIC PLRA+V+VT+ RV+ +I V+WAVA  SAGP   LVGVE +         NGT 
Sbjct: 136 RYLAICRPLRARVLVTRRRVRALIAVLWAVALLSAGPFLFLVGVEQDPGISVVPGLNGTA 195

Query: 191 -----------DPW---------------------DTNECRPTEFAVRSGLLTVMVWVSS 218
                        W                      + ECRP+    + G L VM+WV++
Sbjct: 196 RIASSPLASSPPLWLSRAPPPSPPSGPETAEAAALFSRECRPS--PAQLGALRVMLWVTT 253

Query: 219 IFFFLPVFCLTVLYSLIGRKLWRRRRGDAVVGASLRDQNHKQTVKMLAVVVFAFILCWLP 278
            +FFLP  CL++LY LIGR+LW  RR      AS R++ H+QTV++L VVV AFI+CWLP
Sbjct: 254 AYFFLPFLCLSILYGLIGRELWSSRRPLRGPAASGRERGHRQTVRVLLVVVLAFIICWLP 313

Query: 279 FHVGRYLFSKSFEPGSLEIAQISQYCNLVSFVLFYLSAAINPILYNIMSKKYRVAVFRLL 338
           FHVGR ++  + +     +   SQY N+V+  LFYLSA+INPILYN++SKKYR A F+LL
Sbjct: 314 FHVGRIIYINTEDS---RMMYFSQYFNIVALQLFYLSASINPILYNLISKKYRAAAFKLL 370


>gi|110611243 neurotensin receptor 1 [Homo sapiens]
          Length = 418

 Score =  173 bits (438), Expect = 2e-43
 Identities = 110/311 (35%), Positives = 168/311 (54%), Gaps = 29/311 (9%)

Query: 46  VTATCVALFVVGIAGNLLTMLVVSR---FRELRTTTNLYLSSMAFSDLL-IFLCMPLDLV 101
           VTA  +ALFVVG  GN +T   ++R    + L++T + +L S+A SDLL + L MP++L 
Sbjct: 66  VTAVYLALFVVGTVGNTVTAFTLARKKSLQSLQSTVHYHLGSLALSDLLTLLLAMPVELY 125

Query: 102 R-LWQYRPWNFGDLLCKLFQFVSESCTYATVLTITALSVERYFAICFPLRAKVVVTKGRV 160
             +W + PW FGD  C+ + F+ ++CTYAT L + +LSVERY AIC P +AK ++++ R 
Sbjct: 126 NFIWVHHPWAFGDAGCRGYYFLRDACTYATALNVASLSVERYLAICHPFKAKTLMSRSRT 185

Query: 161 KLVIFVIWAVAFCSAGPIFVLVGVEHENGTDPWDTN--ECRPTEFAVRSGLLTVMVWVSS 218
           K  I  IW  +   A P+   +G E     D        C PT   + +  + V++ V++
Sbjct: 186 KKFISAIWLASALLAVPMLFTMG-EQNRSADGQHAGGLVCTPT---IHTATVKVVIQVNT 241

Query: 219 IF-FFLPVFCLTVLYSLIGRKLWRRRRGDAVVGASL----------------RDQNHKQT 261
              F  P+  ++VL ++I  KL    R  A  G                   R Q  +  
Sbjct: 242 FMSFIFPMVVISVLNTIIANKLTVMVRQAAEQGQVCTVGGEHSTFSMAIEPGRVQALRHG 301

Query: 262 VKMLAVVVFAFILCWLPFHVGRYLFSK-SFEPGSLEIAQISQYCNLVSFVLFYLSAAINP 320
           V++L  VV AF++CWLP+HV R +F   S E  +  +     Y  +V+  LFY+S+ INP
Sbjct: 302 VRVLRAVVIAFVVCWLPYHVRRLMFCYISDEQWTPFLYDFYHYFYMVTNALFYVSSTINP 361

Query: 321 ILYNIMSKKYR 331
           ILYN++S  +R
Sbjct: 362 ILYNLVSANFR 372


>gi|170932505 neuromedin U receptor 2 [Homo sapiens]
          Length = 415

 Score =  168 bits (426), Expect = 6e-42
 Identities = 101/294 (34%), Positives = 172/294 (58%), Gaps = 10/294 (3%)

Query: 46  VTATCVALFVVGIAGNLLTMLVVSRFRELRTTTNLYLSSMAFSDLLIFLC-MPLDLVRLW 104
           V+   V +FVVG+ GN+L  LV+ + + ++T TN YL S+A SDLL+ L  MPL++  +W
Sbjct: 48  VSVVYVPIFVVGVIGNVLVCLVILQHQAMKTPTNYYLFSLAVSDLLVLLLGMPLEVYEMW 107

Query: 105 QYRPWNFGDLLCKLFQFVSESCTYATVLTITALSVERYFAICFPLRAKVVVTKGRVKLVI 164
           +  P+ FG + C     + E+  +A++L+IT +SVERY AI  P RAK+  T+ R   ++
Sbjct: 108 RNYPFLFGPVGCYFKTALFETVCFASILSITTVSVERYVAILHPFRAKLQSTRRRALRIL 167

Query: 165 FVIWAVAFCSAGPIFVLVGVEHE---NGTDPWDTNECRPTEFAVRSGLLTVMVWVSS-IF 220
            ++W  +   + P   + G++     NG+    +  C   +      +   ++ V+S +F
Sbjct: 168 GIVWGFSVLFSLPNTSIHGIKFHYFPNGSLVPGSATCTVIK---PMWIYNFIIQVTSFLF 224

Query: 221 FFLPVFCLTVLYSLIGRKLWRRRRGDAVVG-ASLRDQNHKQTVKMLAVVVFAFILCWLPF 279
           + LP+  ++VLY L+  +L + +  +A  G A+++    K   KML V+V  F +CW PF
Sbjct: 225 YLLPMTVISVLYYLMALRLKKDKSLEADEGNANIQRPCRKSVNKMLFVLVLVFAICWAPF 284

Query: 280 HVGRYLFSKSFEPGSLEIAQISQYCNLVSFVLFYLSAAINPILYNIMSKKYRVA 333
           H+ R  FS   E  S  +A +    ++VS V FYLS+A+NPI+YN++S++++ A
Sbjct: 285 HIDRLFFS-FVEEWSESLAAVFNLVHVVSGVFFYLSSAVNPIIYNLLSRRFQAA 337


>gi|188497623 neuromedin U receptor 1 [Homo sapiens]
          Length = 426

 Score =  167 bits (423), Expect = 1e-41
 Identities = 122/335 (36%), Positives = 179/335 (53%), Gaps = 35/335 (10%)

Query: 25  PGNDSLGDELLQL-FPAP----LLAGVTATCVALFVVGIAGNLLTMLVVSRFRELRTTTN 79
           P + +L DE L+L +  P    L   + AT + +FVVG  GN LT LV+ R + +RT TN
Sbjct: 37  PEDLNLTDEALRLKYLGPQQTELFMPICATYLLIFVVGAVGNGLTCLVILRHKAMRTPTN 96

Query: 80  LYLSSMAFSDLLIFLC-MPLDLVRLWQYRPWNFGDLLCKLFQFVSESCTYATVLTITALS 138
            YL S+A SDLL+ L  +PL+L  +W   P+  G   C     + E    A+VL +TALS
Sbjct: 97  YYLFSLAVSDLLVLLVGLPLELYEMWHNYPFLLGVGGCYFRTLLFEMVCLASVLNVTALS 156

Query: 139 VERYFAICFPLRAKVVVTKGRVKLVIFVIWAVAFCSAGPIFVLVGVEHEN----GTDPWD 194
           VERY A+  PL+A+ +VT+  V+ V+  +W +A   + P   L G+   +    G  P D
Sbjct: 157 VERYVAVVHPLQARSMVTRAHVRRVLGAVWGLAMLCSLPNTSLHGIRQLHVPCRGPVP-D 215

Query: 195 TNECRPTEFAVRSGLLTVMV--WVSSIFFFLPVFCLTVLYSLIGRKLWRRR--------- 243
           +  C      VR   L  MV    + +FF LP+  ++VLY LIG +L R R         
Sbjct: 216 SAVC----MLVRPRALYNMVVQTTALLFFCLPMAIMSVLYLLIGLRLRRERLLLMQEAKG 271

Query: 244 RGDAVVGA------SLRDQNHKQTVKMLAVVVFAFILCWLPFHVGRYLFS-KSFEPGSLE 296
           RG A   +         D+  +Q  KML V+V  F +CW PFH  R ++S  S     L 
Sbjct: 272 RGSAAARSRYTCRLQQHDRGRRQVTKMLFVLVVVFGICWAPFHADRVMWSVVSQWTDGLH 331

Query: 297 IAQISQYCNLVSFVLFYLSAAINPILYNIMSKKYR 331
           +A   Q+ +++S + FYL +A NP+LY++MS ++R
Sbjct: 332 LA--FQHVHVISGIFFYLGSAANPVLYSLMSSRFR 364


>gi|39725940 opioid receptor, kappa 1 [Homo sapiens]
          Length = 380

 Score =  140 bits (354), Expect = 1e-33
 Identities = 86/316 (27%), Positives = 164/316 (51%), Gaps = 15/316 (4%)

Query: 21  WDASPGNDSLGDELLQLFPAPLLAGV----TATCVALFVVGIAGNLLTMLVVSRFRELRT 76
           W     N S G E  QL PA +   +    TA    +FVVG+ GN L M V+ R+ +++T
Sbjct: 33  WAEPDSNGSAGSEDAQLEPAHISPAIPVIITAVYSVVFVVGLVGNSLVMFVIIRYTKMKT 92

Query: 77  TTNLYLSSMAFSDLLIFLCMPLDLVRLWQYRPWNFGDLLCKLFQFVSESCTYATVLTITA 136
            TN+Y+ ++A +D L+   MP     ++    W FGD+LCK+   +     + ++ T+T 
Sbjct: 93  ATNIYIFNLALADALVTTTMPFQST-VYLMNSWPFGDVLCKIVISIDYYNMFTSIFTLTM 151

Query: 137 LSVERYFAICFPLRAKVVVTKGRVKLVIFVIWAVAFCSAGPIFVLVGVEHENGTDPWDTN 196
           +SV+RY A+C P++A    T  + K++   IW ++        VL G +     D  + +
Sbjct: 152 MSVDRYIAVCHPVKALDFRTPLKAKIINICIWLLSSSVGISAIVLGGTKVREDVDVIECS 211

Query: 197 ECRP-TEFAVRSGLLTVMVWVSSIFFFLPVFCLTVLYSLIGRKLWRRRRGDAVVGASLRD 255
              P  +++     + + V++ +  F +PV  + V Y+L+   + R +    + G+  +D
Sbjct: 212 LQFPDDDYSWWDLFMKICVFIFA--FVIPVLIIIVCYTLM---ILRLKSVRLLSGSREKD 266

Query: 256 QNHKQTVKMLAVVVFAFILCWLPFHVGRYLFSKSFEPGSLEIAQISQYCNLVSFVLFYLS 315
           +N ++  +++ VVV  F++CW P H+  ++  ++    S   A +S Y   ++  L Y +
Sbjct: 267 RNLRRITRLVLVVVAVFVVCWTPIHI--FILVEALGSTSHSTAALSSYYFCIA--LGYTN 322

Query: 316 AAINPILYNIMSKKYR 331
           +++NPILY  + + ++
Sbjct: 323 SSLNPILYAFLDENFK 338


>gi|4505513 opiate receptor-like 1 [Homo sapiens]
          Length = 370

 Score =  132 bits (331), Expect = 6e-31
 Identities = 93/322 (28%), Positives = 158/322 (49%), Gaps = 25/322 (7%)

Query: 24  SPGNDSLGDELL------QLFPAPLLAGVTATCVALFVVGIAGNLLTMLVVSRFRELRTT 77
           SP +  L   LL         P  L   +    +A+ V G+ GN L M V+ R  +++T 
Sbjct: 26  SPNHSLLPPHLLLNASHGAFLPLGLKVTIVGLYLAVCVGGLLGNCLVMYVILRHTKMKTA 85

Query: 78  TNLYLSSMAFSDLLIFLCMPLDLVRLWQYRPWNFGDLLCKLFQFVSESCTYATVLTITAL 137
           TN+Y+ ++A +D L+ L +P     +     W FG+ LCK    +     + +  T+TA+
Sbjct: 86  TNIYIFNLALADTLVLLTLPFQGTDI-LLGFWPFGNALCKTVIAIDYYNMFTSTFTLTAM 144

Query: 138 SVERYFAICFPLRAKVVVTKGRVKLVIFVIWAVAFCSAGPIFVLVGVEHENGTDPWDTNE 197
           SV+RY AIC P+RA  V T  + + V   IWA+A     P+ ++   + E+     +  E
Sbjct: 145 SVDRYVAICHPIRALDVRTSSKAQAVNVAIWALASVVGVPVAIMGSAQVED-----EEIE 199

Query: 198 CR---PTEFAVRSGLLTVMVWVSSIFFFLPVFCLTVLYSLIGRKLWRRRRGDAVVGASLR 254
           C    PT       +  + +++ S  F +PV  ++V YSL+ R+L   R    + G+  +
Sbjct: 200 CLVEIPTPQDYWGPVFAICIFLFS--FIVPVLVISVCYSLMIRRL---RGVRLLSGSREK 254

Query: 255 DQNHKQTVKMLAVVVFAFILCWLPFHVGRYLFSKSFEPGSLEIAQISQYCNLVSFVLFYL 314
           D+N ++  +++ VVV  F+ CW P  V         +P S     I ++C      L Y+
Sbjct: 255 DRNLRRITRLVLVVVAVFVGCWTPVQVFVLAQGLGVQPSSETAVAILRFCT----ALGYV 310

Query: 315 SAAINPILYNIMSKKYRVAVFR 336
           ++ +NPILY  + + ++ A FR
Sbjct: 311 NSCLNPILYAFLDENFK-ACFR 331


>gi|33286424 opiate receptor-like 1 [Homo sapiens]
          Length = 370

 Score =  132 bits (331), Expect = 6e-31
 Identities = 93/322 (28%), Positives = 158/322 (49%), Gaps = 25/322 (7%)

Query: 24  SPGNDSLGDELL------QLFPAPLLAGVTATCVALFVVGIAGNLLTMLVVSRFRELRTT 77
           SP +  L   LL         P  L   +    +A+ V G+ GN L M V+ R  +++T 
Sbjct: 26  SPNHSLLPPHLLLNASHGAFLPLGLKVTIVGLYLAVCVGGLLGNCLVMYVILRHTKMKTA 85

Query: 78  TNLYLSSMAFSDLLIFLCMPLDLVRLWQYRPWNFGDLLCKLFQFVSESCTYATVLTITAL 137
           TN+Y+ ++A +D L+ L +P     +     W FG+ LCK    +     + +  T+TA+
Sbjct: 86  TNIYIFNLALADTLVLLTLPFQGTDI-LLGFWPFGNALCKTVIAIDYYNMFTSTFTLTAM 144

Query: 138 SVERYFAICFPLRAKVVVTKGRVKLVIFVIWAVAFCSAGPIFVLVGVEHENGTDPWDTNE 197
           SV+RY AIC P+RA  V T  + + V   IWA+A     P+ ++   + E+     +  E
Sbjct: 145 SVDRYVAICHPIRALDVRTSSKAQAVNVAIWALASVVGVPVAIMGSAQVED-----EEIE 199

Query: 198 CR---PTEFAVRSGLLTVMVWVSSIFFFLPVFCLTVLYSLIGRKLWRRRRGDAVVGASLR 254
           C    PT       +  + +++ S  F +PV  ++V YSL+ R+L   R    + G+  +
Sbjct: 200 CLVEIPTPQDYWGPVFAICIFLFS--FIVPVLVISVCYSLMIRRL---RGVRLLSGSREK 254

Query: 255 DQNHKQTVKMLAVVVFAFILCWLPFHVGRYLFSKSFEPGSLEIAQISQYCNLVSFVLFYL 314
           D+N ++  +++ VVV  F+ CW P  V         +P S     I ++C      L Y+
Sbjct: 255 DRNLRRITRLVLVVVAVFVGCWTPVQVFVLAQGLGVQPSSETAVAILRFCT----ALGYV 310

Query: 315 SAAINPILYNIMSKKYRVAVFR 336
           ++ +NPILY  + + ++ A FR
Sbjct: 311 NSCLNPILYAFLDENFK-ACFR 331


>gi|223718055 opioid receptor, mu 1 isoform MOR-1H [Homo sapiens]
          Length = 493

 Score =  130 bits (326), Expect = 2e-30
 Identities = 88/338 (26%), Positives = 164/338 (48%), Gaps = 21/338 (6%)

Query: 3   NATPSEEPGFNLTLADLDWDAS----PGNDSLGDELLQLFPAPLLAGVTA-TCVALF--- 54
           + +P+  PG  + L+ LD + S    P    LG       P    + +TA T +AL+   
Sbjct: 114 SCSPAPSPGSWVNLSHLDGNLSDPCGPNRTDLGGRDSLCPPTGSPSMITAITIMALYSIV 173

Query: 55  -VVGIAGNLLTMLVVSRFRELRTTTNLYLSSMAFSDLLIFLCMPLDLVRLWQYRPWNFGD 113
            VVG+ GN L M V+ R+ +++T TN+Y+ ++A +D L    +P   V  +    W FG 
Sbjct: 174 CVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADALATSTLPFQSVN-YLMGTWPFGT 232

Query: 114 LLCKLFQFVSESCTYATVLTITALSVERYFAICFPLRAKVVVTKGRVKLVIFVIWAVAFC 173
           +LCK+   +     + ++ T+  +SV+RY A+C P++A    T    K++    W ++  
Sbjct: 233 ILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKIINVCNWILSSA 292

Query: 174 SAGPIFVLVGVEHENGTDPWDTNECRPTEFAVRSGLLTVMVWVSSIFFFLPVFCLTVLYS 233
              P+  +   ++  G+         PT +     LL + V++ +  F +PV  +TV Y 
Sbjct: 293 IGLPVMFMATTKYRQGSIDCTLTFSHPTWY--WENLLKICVFIFA--FIMPVLIITVCYG 348

Query: 234 LIGRKLWRRRRGDAVVGASLRDQNHKQTVKMLAVVVFAFILCWLPFHVGRYLFSKSFEPG 293
           L+   + R +    + G+  +D+N ++  +M+ VVV  FI+CW P H+   + +    P 
Sbjct: 349 LM---ILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHIYVIIKALVTIPE 405

Query: 294 SLEIAQISQYCNLVSFVLFYLSAAINPILYNIMSKKYR 331
           +        +C      L Y ++ +NP+LY  + + ++
Sbjct: 406 TTFQTVSWHFC----IALGYTNSCLNPVLYAFLDENFK 439


>gi|117940060 opioid receptor, mu 1 isoform MOR-1 [Homo sapiens]
          Length = 400

 Score =  130 bits (326), Expect = 2e-30
 Identities = 88/338 (26%), Positives = 164/338 (48%), Gaps = 21/338 (6%)

Query: 3   NATPSEEPGFNLTLADLDWDAS----PGNDSLGDELLQLFPAPLLAGVTA-TCVALF--- 54
           + +P+  PG  + L+ LD + S    P    LG       P    + +TA T +AL+   
Sbjct: 21  SCSPAPSPGSWVNLSHLDGNLSDPCGPNRTDLGGRDSLCPPTGSPSMITAITIMALYSIV 80

Query: 55  -VVGIAGNLLTMLVVSRFRELRTTTNLYLSSMAFSDLLIFLCMPLDLVRLWQYRPWNFGD 113
            VVG+ GN L M V+ R+ +++T TN+Y+ ++A +D L    +P   V  +    W FG 
Sbjct: 81  CVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADALATSTLPFQSVN-YLMGTWPFGT 139

Query: 114 LLCKLFQFVSESCTYATVLTITALSVERYFAICFPLRAKVVVTKGRVKLVIFVIWAVAFC 173
           +LCK+   +     + ++ T+  +SV+RY A+C P++A    T    K++    W ++  
Sbjct: 140 ILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKIINVCNWILSSA 199

Query: 174 SAGPIFVLVGVEHENGTDPWDTNECRPTEFAVRSGLLTVMVWVSSIFFFLPVFCLTVLYS 233
              P+  +   ++  G+         PT +     LL + V++ +  F +PV  +TV Y 
Sbjct: 200 IGLPVMFMATTKYRQGSIDCTLTFSHPTWY--WENLLKICVFIFA--FIMPVLIITVCYG 255

Query: 234 LIGRKLWRRRRGDAVVGASLRDQNHKQTVKMLAVVVFAFILCWLPFHVGRYLFSKSFEPG 293
           L+   + R +    + G+  +D+N ++  +M+ VVV  FI+CW P H+   + +    P 
Sbjct: 256 LM---ILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHIYVIIKALVTIPE 312

Query: 294 SLEIAQISQYCNLVSFVLFYLSAAINPILYNIMSKKYR 331
           +        +C      L Y ++ +NP+LY  + + ++
Sbjct: 313 TTFQTVSWHFC----IALGYTNSCLNPVLYAFLDENFK 346


>gi|223718712 opioid receptor, mu 1 isoform MOR-1B5 [Homo sapiens]
          Length = 420

 Score =  130 bits (326), Expect = 2e-30
 Identities = 88/338 (26%), Positives = 164/338 (48%), Gaps = 21/338 (6%)

Query: 3   NATPSEEPGFNLTLADLDWDAS----PGNDSLGDELLQLFPAPLLAGVTA-TCVALF--- 54
           + +P+  PG  + L+ LD + S    P    LG       P    + +TA T +AL+   
Sbjct: 21  SCSPAPSPGSWVNLSHLDGNLSDPCGPNRTDLGGRDSLCPPTGSPSMITAITIMALYSIV 80

Query: 55  -VVGIAGNLLTMLVVSRFRELRTTTNLYLSSMAFSDLLIFLCMPLDLVRLWQYRPWNFGD 113
            VVG+ GN L M V+ R+ +++T TN+Y+ ++A +D L    +P   V  +    W FG 
Sbjct: 81  CVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADALATSTLPFQSVN-YLMGTWPFGT 139

Query: 114 LLCKLFQFVSESCTYATVLTITALSVERYFAICFPLRAKVVVTKGRVKLVIFVIWAVAFC 173
           +LCK+   +     + ++ T+  +SV+RY A+C P++A    T    K++    W ++  
Sbjct: 140 ILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKIINVCNWILSSA 199

Query: 174 SAGPIFVLVGVEHENGTDPWDTNECRPTEFAVRSGLLTVMVWVSSIFFFLPVFCLTVLYS 233
              P+  +   ++  G+         PT +     LL + V++ +  F +PV  +TV Y 
Sbjct: 200 IGLPVMFMATTKYRQGSIDCTLTFSHPTWY--WENLLKICVFIFA--FIMPVLIITVCYG 255

Query: 234 LIGRKLWRRRRGDAVVGASLRDQNHKQTVKMLAVVVFAFILCWLPFHVGRYLFSKSFEPG 293
           L+   + R +    + G+  +D+N ++  +M+ VVV  FI+CW P H+   + +    P 
Sbjct: 256 LM---ILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHIYVIIKALVTIPE 312

Query: 294 SLEIAQISQYCNLVSFVLFYLSAAINPILYNIMSKKYR 331
           +        +C      L Y ++ +NP+LY  + + ++
Sbjct: 313 TTFQTVSWHFC----IALGYTNSCLNPVLYAFLDENFK 346


>gi|223718719 opioid receptor, mu 1 isoform MOR-1B2 [Homo sapiens]
          Length = 397

 Score =  130 bits (326), Expect = 2e-30
 Identities = 88/338 (26%), Positives = 164/338 (48%), Gaps = 21/338 (6%)

Query: 3   NATPSEEPGFNLTLADLDWDAS----PGNDSLGDELLQLFPAPLLAGVTA-TCVALF--- 54
           + +P+  PG  + L+ LD + S    P    LG       P    + +TA T +AL+   
Sbjct: 21  SCSPAPSPGSWVNLSHLDGNLSDPCGPNRTDLGGRDSLCPPTGSPSMITAITIMALYSIV 80

Query: 55  -VVGIAGNLLTMLVVSRFRELRTTTNLYLSSMAFSDLLIFLCMPLDLVRLWQYRPWNFGD 113
            VVG+ GN L M V+ R+ +++T TN+Y+ ++A +D L    +P   V  +    W FG 
Sbjct: 81  CVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADALATSTLPFQSVN-YLMGTWPFGT 139

Query: 114 LLCKLFQFVSESCTYATVLTITALSVERYFAICFPLRAKVVVTKGRVKLVIFVIWAVAFC 173
           +LCK+   +     + ++ T+  +SV+RY A+C P++A    T    K++    W ++  
Sbjct: 140 ILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKIINVCNWILSSA 199

Query: 174 SAGPIFVLVGVEHENGTDPWDTNECRPTEFAVRSGLLTVMVWVSSIFFFLPVFCLTVLYS 233
              P+  +   ++  G+         PT +     LL + V++ +  F +PV  +TV Y 
Sbjct: 200 IGLPVMFMATTKYRQGSIDCTLTFSHPTWY--WENLLKICVFIFA--FIMPVLIITVCYG 255

Query: 234 LIGRKLWRRRRGDAVVGASLRDQNHKQTVKMLAVVVFAFILCWLPFHVGRYLFSKSFEPG 293
           L+   + R +    + G+  +D+N ++  +M+ VVV  FI+CW P H+   + +    P 
Sbjct: 256 LM---ILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHIYVIIKALVTIPE 312

Query: 294 SLEIAQISQYCNLVSFVLFYLSAAINPILYNIMSKKYR 331
           +        +C      L Y ++ +NP+LY  + + ++
Sbjct: 313 TTFQTVSWHFC----IALGYTNSCLNPVLYAFLDENFK 346


>gi|223718077 opioid receptor, mu 1 isoform MOR-1B3 [Homo sapiens]
          Length = 403

 Score =  130 bits (326), Expect = 2e-30
 Identities = 88/338 (26%), Positives = 164/338 (48%), Gaps = 21/338 (6%)

Query: 3   NATPSEEPGFNLTLADLDWDAS----PGNDSLGDELLQLFPAPLLAGVTA-TCVALF--- 54
           + +P+  PG  + L+ LD + S    P    LG       P    + +TA T +AL+   
Sbjct: 21  SCSPAPSPGSWVNLSHLDGNLSDPCGPNRTDLGGRDSLCPPTGSPSMITAITIMALYSIV 80

Query: 55  -VVGIAGNLLTMLVVSRFRELRTTTNLYLSSMAFSDLLIFLCMPLDLVRLWQYRPWNFGD 113
            VVG+ GN L M V+ R+ +++T TN+Y+ ++A +D L    +P   V  +    W FG 
Sbjct: 81  CVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADALATSTLPFQSVN-YLMGTWPFGT 139

Query: 114 LLCKLFQFVSESCTYATVLTITALSVERYFAICFPLRAKVVVTKGRVKLVIFVIWAVAFC 173
           +LCK+   +     + ++ T+  +SV+RY A+C P++A    T    K++    W ++  
Sbjct: 140 ILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKIINVCNWILSSA 199

Query: 174 SAGPIFVLVGVEHENGTDPWDTNECRPTEFAVRSGLLTVMVWVSSIFFFLPVFCLTVLYS 233
              P+  +   ++  G+         PT +     LL + V++ +  F +PV  +TV Y 
Sbjct: 200 IGLPVMFMATTKYRQGSIDCTLTFSHPTWY--WENLLKICVFIFA--FIMPVLIITVCYG 255

Query: 234 LIGRKLWRRRRGDAVVGASLRDQNHKQTVKMLAVVVFAFILCWLPFHVGRYLFSKSFEPG 293
           L+   + R +    + G+  +D+N ++  +M+ VVV  FI+CW P H+   + +    P 
Sbjct: 256 LM---ILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHIYVIIKALVTIPE 312

Query: 294 SLEIAQISQYCNLVSFVLFYLSAAINPILYNIMSKKYR 331
           +        +C      L Y ++ +NP+LY  + + ++
Sbjct: 313 TTFQTVSWHFC----IALGYTNSCLNPVLYAFLDENFK 346


>gi|223718716 opioid receptor, mu 1 isoform MOR-1B1 [Homo sapiens]
          Length = 406

 Score =  130 bits (326), Expect = 2e-30
 Identities = 88/338 (26%), Positives = 164/338 (48%), Gaps = 21/338 (6%)

Query: 3   NATPSEEPGFNLTLADLDWDAS----PGNDSLGDELLQLFPAPLLAGVTA-TCVALF--- 54
           + +P+  PG  + L+ LD + S    P    LG       P    + +TA T +AL+   
Sbjct: 21  SCSPAPSPGSWVNLSHLDGNLSDPCGPNRTDLGGRDSLCPPTGSPSMITAITIMALYSIV 80

Query: 55  -VVGIAGNLLTMLVVSRFRELRTTTNLYLSSMAFSDLLIFLCMPLDLVRLWQYRPWNFGD 113
            VVG+ GN L M V+ R+ +++T TN+Y+ ++A +D L    +P   V  +    W FG 
Sbjct: 81  CVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADALATSTLPFQSVN-YLMGTWPFGT 139

Query: 114 LLCKLFQFVSESCTYATVLTITALSVERYFAICFPLRAKVVVTKGRVKLVIFVIWAVAFC 173
           +LCK+   +     + ++ T+  +SV+RY A+C P++A    T    K++    W ++  
Sbjct: 140 ILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKIINVCNWILSSA 199

Query: 174 SAGPIFVLVGVEHENGTDPWDTNECRPTEFAVRSGLLTVMVWVSSIFFFLPVFCLTVLYS 233
              P+  +   ++  G+         PT +     LL + V++ +  F +PV  +TV Y 
Sbjct: 200 IGLPVMFMATTKYRQGSIDCTLTFSHPTWY--WENLLKICVFIFA--FIMPVLIITVCYG 255

Query: 234 LIGRKLWRRRRGDAVVGASLRDQNHKQTVKMLAVVVFAFILCWLPFHVGRYLFSKSFEPG 293
           L+   + R +    + G+  +D+N ++  +M+ VVV  FI+CW P H+   + +    P 
Sbjct: 256 LM---ILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHIYVIIKALVTIPE 312

Query: 294 SLEIAQISQYCNLVSFVLFYLSAAINPILYNIMSKKYR 331
           +        +C      L Y ++ +NP+LY  + + ++
Sbjct: 313 TTFQTVSWHFC----IALGYTNSCLNPVLYAFLDENFK 346


>gi|117940058 opioid receptor, mu 1 isoform MOR-1A [Homo sapiens]
          Length = 392

 Score =  130 bits (326), Expect = 2e-30
 Identities = 88/338 (26%), Positives = 164/338 (48%), Gaps = 21/338 (6%)

Query: 3   NATPSEEPGFNLTLADLDWDAS----PGNDSLGDELLQLFPAPLLAGVTA-TCVALF--- 54
           + +P+  PG  + L+ LD + S    P    LG       P    + +TA T +AL+   
Sbjct: 21  SCSPAPSPGSWVNLSHLDGNLSDPCGPNRTDLGGRDSLCPPTGSPSMITAITIMALYSIV 80

Query: 55  -VVGIAGNLLTMLVVSRFRELRTTTNLYLSSMAFSDLLIFLCMPLDLVRLWQYRPWNFGD 113
            VVG+ GN L M V+ R+ +++T TN+Y+ ++A +D L    +P   V  +    W FG 
Sbjct: 81  CVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADALATSTLPFQSVN-YLMGTWPFGT 139

Query: 114 LLCKLFQFVSESCTYATVLTITALSVERYFAICFPLRAKVVVTKGRVKLVIFVIWAVAFC 173
           +LCK+   +     + ++ T+  +SV+RY A+C P++A    T    K++    W ++  
Sbjct: 140 ILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKIINVCNWILSSA 199

Query: 174 SAGPIFVLVGVEHENGTDPWDTNECRPTEFAVRSGLLTVMVWVSSIFFFLPVFCLTVLYS 233
              P+  +   ++  G+         PT +     LL + V++ +  F +PV  +TV Y 
Sbjct: 200 IGLPVMFMATTKYRQGSIDCTLTFSHPTWY--WENLLKICVFIFA--FIMPVLIITVCYG 255

Query: 234 LIGRKLWRRRRGDAVVGASLRDQNHKQTVKMLAVVVFAFILCWLPFHVGRYLFSKSFEPG 293
           L+   + R +    + G+  +D+N ++  +M+ VVV  FI+CW P H+   + +    P 
Sbjct: 256 LM---ILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHIYVIIKALVTIPE 312

Query: 294 SLEIAQISQYCNLVSFVLFYLSAAINPILYNIMSKKYR 331
           +        +C      L Y ++ +NP+LY  + + ++
Sbjct: 313 TTFQTVSWHFC----IALGYTNSCLNPVLYAFLDENFK 346


>gi|223717969 opioid receptor, mu 1 isoform MOR-1B4 [Homo sapiens]
          Length = 389

 Score =  130 bits (326), Expect = 2e-30
 Identities = 88/338 (26%), Positives = 164/338 (48%), Gaps = 21/338 (6%)

Query: 3   NATPSEEPGFNLTLADLDWDAS----PGNDSLGDELLQLFPAPLLAGVTA-TCVALF--- 54
           + +P+  PG  + L+ LD + S    P    LG       P    + +TA T +AL+   
Sbjct: 21  SCSPAPSPGSWVNLSHLDGNLSDPCGPNRTDLGGRDSLCPPTGSPSMITAITIMALYSIV 80

Query: 55  -VVGIAGNLLTMLVVSRFRELRTTTNLYLSSMAFSDLLIFLCMPLDLVRLWQYRPWNFGD 113
            VVG+ GN L M V+ R+ +++T TN+Y+ ++A +D L    +P   V  +    W FG 
Sbjct: 81  CVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADALATSTLPFQSVN-YLMGTWPFGT 139

Query: 114 LLCKLFQFVSESCTYATVLTITALSVERYFAICFPLRAKVVVTKGRVKLVIFVIWAVAFC 173
           +LCK+   +     + ++ T+  +SV+RY A+C P++A    T    K++    W ++  
Sbjct: 140 ILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKIINVCNWILSSA 199

Query: 174 SAGPIFVLVGVEHENGTDPWDTNECRPTEFAVRSGLLTVMVWVSSIFFFLPVFCLTVLYS 233
              P+  +   ++  G+         PT +     LL + V++ +  F +PV  +TV Y 
Sbjct: 200 IGLPVMFMATTKYRQGSIDCTLTFSHPTWY--WENLLKICVFIFA--FIMPVLIITVCYG 255

Query: 234 LIGRKLWRRRRGDAVVGASLRDQNHKQTVKMLAVVVFAFILCWLPFHVGRYLFSKSFEPG 293
           L+   + R +    + G+  +D+N ++  +M+ VVV  FI+CW P H+   + +    P 
Sbjct: 256 LM---ILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHIYVIIKALVTIPE 312

Query: 294 SLEIAQISQYCNLVSFVLFYLSAAINPILYNIMSKKYR 331
           +        +C      L Y ++ +NP+LY  + + ++
Sbjct: 313 TTFQTVSWHFC----IALGYTNSCLNPVLYAFLDENFK 346


>gi|117940055 opioid receptor, mu 1 isoform MOR-1O [Homo sapiens]
          Length = 418

 Score =  130 bits (326), Expect = 2e-30
 Identities = 88/338 (26%), Positives = 164/338 (48%), Gaps = 21/338 (6%)

Query: 3   NATPSEEPGFNLTLADLDWDAS----PGNDSLGDELLQLFPAPLLAGVTA-TCVALF--- 54
           + +P+  PG  + L+ LD + S    P    LG       P    + +TA T +AL+   
Sbjct: 21  SCSPAPSPGSWVNLSHLDGNLSDPCGPNRTDLGGRDSLCPPTGSPSMITAITIMALYSIV 80

Query: 55  -VVGIAGNLLTMLVVSRFRELRTTTNLYLSSMAFSDLLIFLCMPLDLVRLWQYRPWNFGD 113
            VVG+ GN L M V+ R+ +++T TN+Y+ ++A +D L    +P   V  +    W FG 
Sbjct: 81  CVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADALATSTLPFQSVN-YLMGTWPFGT 139

Query: 114 LLCKLFQFVSESCTYATVLTITALSVERYFAICFPLRAKVVVTKGRVKLVIFVIWAVAFC 173
           +LCK+   +     + ++ T+  +SV+RY A+C P++A    T    K++    W ++  
Sbjct: 140 ILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKIINVCNWILSSA 199

Query: 174 SAGPIFVLVGVEHENGTDPWDTNECRPTEFAVRSGLLTVMVWVSSIFFFLPVFCLTVLYS 233
              P+  +   ++  G+         PT +     LL + V++ +  F +PV  +TV Y 
Sbjct: 200 IGLPVMFMATTKYRQGSIDCTLTFSHPTWY--WENLLKICVFIFA--FIMPVLIITVCYG 255

Query: 234 LIGRKLWRRRRGDAVVGASLRDQNHKQTVKMLAVVVFAFILCWLPFHVGRYLFSKSFEPG 293
           L+   + R +    + G+  +D+N ++  +M+ VVV  FI+CW P H+   + +    P 
Sbjct: 256 LM---ILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHIYVIIKALVTIPE 312

Query: 294 SLEIAQISQYCNLVSFVLFYLSAAINPILYNIMSKKYR 331
           +        +C      L Y ++ +NP+LY  + + ++
Sbjct: 313 TTFQTVSWHFC----IALGYTNSCLNPVLYAFLDENFK 346


>gi|117940054 opioid receptor, mu 1 isoform MOR-1X [Homo sapiens]
          Length = 446

 Score =  130 bits (326), Expect = 2e-30
 Identities = 88/338 (26%), Positives = 164/338 (48%), Gaps = 21/338 (6%)

Query: 3   NATPSEEPGFNLTLADLDWDAS----PGNDSLGDELLQLFPAPLLAGVTA-TCVALF--- 54
           + +P+  PG  + L+ LD + S    P    LG       P    + +TA T +AL+   
Sbjct: 21  SCSPAPSPGSWVNLSHLDGNLSDPCGPNRTDLGGRDSLCPPTGSPSMITAITIMALYSIV 80

Query: 55  -VVGIAGNLLTMLVVSRFRELRTTTNLYLSSMAFSDLLIFLCMPLDLVRLWQYRPWNFGD 113
            VVG+ GN L M V+ R+ +++T TN+Y+ ++A +D L    +P   V  +    W FG 
Sbjct: 81  CVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADALATSTLPFQSVN-YLMGTWPFGT 139

Query: 114 LLCKLFQFVSESCTYATVLTITALSVERYFAICFPLRAKVVVTKGRVKLVIFVIWAVAFC 173
           +LCK+   +     + ++ T+  +SV+RY A+C P++A    T    K++    W ++  
Sbjct: 140 ILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKIINVCNWILSSA 199

Query: 174 SAGPIFVLVGVEHENGTDPWDTNECRPTEFAVRSGLLTVMVWVSSIFFFLPVFCLTVLYS 233
              P+  +   ++  G+         PT +     LL + V++ +  F +PV  +TV Y 
Sbjct: 200 IGLPVMFMATTKYRQGSIDCTLTFSHPTWY--WENLLKICVFIFA--FIMPVLIITVCYG 255

Query: 234 LIGRKLWRRRRGDAVVGASLRDQNHKQTVKMLAVVVFAFILCWLPFHVGRYLFSKSFEPG 293
           L+   + R +    + G+  +D+N ++  +M+ VVV  FI+CW P H+   + +    P 
Sbjct: 256 LM---ILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHIYVIIKALVTIPE 312

Query: 294 SLEIAQISQYCNLVSFVLFYLSAAINPILYNIMSKKYR 331
           +        +C      L Y ++ +NP+LY  + + ++
Sbjct: 313 TTFQTVSWHFC----IALGYTNSCLNPVLYAFLDENFK 346


>gi|157738685 G protein-coupled receptor 103 [Homo sapiens]
          Length = 431

 Score =  126 bits (317), Expect = 3e-29
 Identities = 86/304 (28%), Positives = 149/304 (49%), Gaps = 15/304 (4%)

Query: 39  PAPLLAGVTATCVALFVVGIAGNLLTMLVVSRFRELRTTTNLYLSSMAFSDLLI-FLCMP 97
           P      +  T V +F + + GN L   VV+R + +RT TN+++ S+A SDLLI F C+P
Sbjct: 41  PGRAKLALVLTGVLIFALALFGNALVFYVVTRSKAMRTVTNIFICSLALSDLLITFFCIP 100

Query: 98  LDLVRLWQYRPWNFGDLLCKLFQFVSESCTYATVLTITALSVERYFAICFPLRAKVVVTK 157
           + +++      W  G  +CK+  FV  +     +LT+T ++VER+  +  P + K   T 
Sbjct: 101 VTMLQNISDN-WLGGAFICKMVPFVQSTAVVTEILTMTCIAVERHQGLVHPFKMKWQYTN 159

Query: 158 GRVKLVIFVIWAVAFCSAGPIFVLVGVEHENGTDPWDTNECRPTEFA--VRSGLLTVMVW 215
            R   ++ V+W VA     P++ +  +E +        + C   E+   V   + T  + 
Sbjct: 160 RRAFTMLGVVWLVAVIVGSPMWHVQQLEIKYDFLYEKEHICCLEEWTSPVHQKIYTTFIL 219

Query: 216 VSSIFFFLPVFCLTVLYSLIGRKLW-RRRRGDAVVGASLRD-------QNHKQTVKMLAV 267
           V  I F LP+  + +LYS IG +LW ++R GD  V  ++         +  K+ V M+  
Sbjct: 220 V--ILFLLPLMVMLILYSKIGYELWIKKRVGDGSVLRTIHGKEMSKIARKKKRAVIMMVT 277

Query: 268 VVFAFILCWLPFHVGRYLFSKSFEPGSLEIAQISQYCNLVSFVLFYLSAAINPILYNIMS 327
           VV  F +CW PFHV   +   S      +   I     +V  ++ + ++  NPI+Y  M+
Sbjct: 278 VVALFAVCWAPFHVVHMMIEYSNFEKEYDDVTIKMIFAIVQ-IIGFSNSICNPIVYAFMN 336

Query: 328 KKYR 331
           + ++
Sbjct: 337 ENFK 340


>gi|63477962 opioid receptor, delta 1 [Homo sapiens]
          Length = 372

 Score =  124 bits (311), Expect = 1e-28
 Identities = 81/303 (26%), Positives = 151/303 (49%), Gaps = 16/303 (5%)

Query: 42  LLAGVTATCVALFVVGIAGNLLTMLVVSRFRELRTTTNLYLSSMAFSDLLIFLCMPLDLV 101
           L   +TA   A+  VG+ GN+L M  + R+ +++T TN+Y+ ++A +D L    +P    
Sbjct: 48  LAIAITALYSAVCAVGLLGNVLVMFGIVRYTKMKTATNIYIFNLALADALATSTLPFQSA 107

Query: 102 RLWQYRPWNFGDLLCKLFQFVSESCTYATVLTITALSVERYFAICFPLRAKVVVTKGRVK 161
           + +    W FG+LLCK    +     + ++ T+T +SV+RY A+C P++A    T  + K
Sbjct: 108 K-YLMETWPFGELLCKAVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPAKAK 166

Query: 162 LVIFVIWAVAFCSAGPIFVLVGVEHENGTDPWDTNECRPTEFAVRSGLLTVMVWVSSIFF 221
           L+   IW +A     PI V+      +G          P+ +      + V ++     F
Sbjct: 167 LINICIWVLASGVGVPIMVMAVTRPRDGAVVCMLQFPSPSWYWDTVTKICVFLFA----F 222

Query: 222 FLPVFCLTVLYSLIGRKLWRRRRGDAVVGASLRDQNHKQTVKMLAVVVFAFILCWLPFHV 281
            +P+  +TV Y L+   L R R    + G+  +D++ ++  +M+ VVV AF++CW P H+
Sbjct: 223 VVPILIITVCYGLM---LLRLRSVRLLSGSKEKDRSLRRITRMVLVVVGAFVVCWAPIHI 279

Query: 282 GRYLFS--KSFEPGSLEIAQISQYCNLVSFVLFYLSAAINPILYNIMSKKYRVAVFRLLG 339
              +++         L +A +      +   L Y ++++NP+LY  + + ++   FR L 
Sbjct: 280 FVIVWTLVDIDRRDPLVVAALH-----LCIALGYANSSLNPVLYAFLDENFK-RCFRQLC 333

Query: 340 FEP 342
            +P
Sbjct: 334 RKP 336


>gi|149944554 somatostatin receptor 4 [Homo sapiens]
          Length = 388

 Score =  124 bits (310), Expect = 2e-28
 Identities = 84/295 (28%), Positives = 138/295 (46%), Gaps = 18/295 (6%)

Query: 46  VTATCVALFV--VGIAGNLLTMLVVSRFRELRTTTNLYLSSMAFSDLLIFLCMPLDLVRL 103
           V   C+   V  VG+ GN L + V+ R+ +++T TN+YL ++A +D L  L +P  +   
Sbjct: 48  VAIQCIYALVCLVGLVGNALVIFVILRYAKMKTATNIYLLNLAVADELFMLSVPF-VASS 106

Query: 104 WQYRPWNFGDLLCKLFQFVSESCTYATVLTITALSVERYFAICFPLRAKVVVTKGRVKLV 163
              R W FG +LC+    V     + +V  +T LSV+RY A+  PLRA         KL+
Sbjct: 107 AALRHWPFGSVLCRAVLSVDGLNMFTSVFCLTVLSVDRYVAVVHPLRAATYRRPSVAKLI 166

Query: 164 IFVIWAVAFCSAGPIFVLVGVEHENGTDPWDTNECRPTEFAVRSGLLTVMVWVSSIFFFL 223
              +W  +     PI +        G      N     ++   +     +V+   + F L
Sbjct: 167 NLGVWLASLLVTLPIAIFADTRPARGGQAVACN----LQWPHPAWSAVFVVYTFLLGFLL 222

Query: 224 PVFCLTVLYSLIGRKLWRRRRGDAVVGASLRDQNHKQTVKMLAVVVFAFILCWLPFHVGR 283
           PV  + + Y LI  K+   R      G   R ++ K+  +++ +VV  F+LCW+PF+V +
Sbjct: 223 PVLAIGLCYLLIVGKM---RAVALRAGWQQRRRSEKKITRLVLMVVVVFVLCWMPFYVVQ 279

Query: 284 YLFSKSFEPGSLEIAQISQYCNLVSFVLFYLSAAINPILYNIMSKKYRVAVFRLL 338
            L        +L +  +    N VS +L Y ++  NPILY  +S  +R    R+L
Sbjct: 280 LL--------NLFVTSLDATVNHVSLILSYANSCANPILYGFLSDNFRRFFQRVL 326


>gi|4507681 thyrotropin-releasing hormone receptor [Homo sapiens]
          Length = 398

 Score =  124 bits (310), Expect = 2e-28
 Identities = 87/306 (28%), Positives = 140/306 (45%), Gaps = 33/306 (10%)

Query: 56  VGIAGNLLTMLVVSRFRELRTTTNLYLSSMAFSDLLIFLCMPLDLVRLWQYRPWNFGDLL 115
           +GI GN++ +LVV R + +RT TN YL S+A +DL++ +   L  +    Y  W +G + 
Sbjct: 38  LGIVGNIMVVLVVMRTKHMRTPTNCYLVSLAVADLMVLVAAGLPNITDSIYGSWVYGYVG 97

Query: 116 CKLFQFVSESCTYATVLTITALSVERYFAICFPLRAKVVVTKGRVKLVIFVIWAVAFCSA 175
           C    ++      A+  +ITA ++ERY AIC P++A+ + T  R K +I  +WA      
Sbjct: 98  CLCITYLQYLGINASSCSITAFTIERYIAICHPIKAQFLCTFSRAKKIIIFVWAFTSLYC 157

Query: 176 GPIFVLVGVEHENGTDPWDTNECRPTEFAVRSGLLTVMVWVSSIFFFLPVFCLTVLYSLI 235
              F L+ +   N +   D           R+    + +    +F+ +P+   TVLY  I
Sbjct: 158 MLWFFLLDL---NISTYKDAIVISCGYKISRNYYSPIYLMDFGVFYVVPMILATVLYGFI 214

Query: 236 GR---------------KLWRRRRGDAVVGASLRDQN---------HKQTVKMLAVVVFA 271
            R               K W+          ++   N          KQ  KMLAVVV  
Sbjct: 215 ARILFLNPIPSDPKENSKTWKNDSTHQNTNLNVNTSNRCFNSTVSSRKQVTKMLAVVVIL 274

Query: 272 FILCWLPFHVGRYLFSKSFEPGSLEIAQISQYCNLVSFVLFYLSAAINPILYNIMSKKYR 331
           F L W+P+     +   SF     +      +C     +  YL++AINP++YN+MS+K+R
Sbjct: 275 FALLWMPYRT--LVVVNSFLSSPFQENWFLLFCR----ICIYLNSAINPVIYNLMSQKFR 328

Query: 332 VAVFRL 337
            A  +L
Sbjct: 329 AAFRKL 334


>gi|4503905 galanin receptor 2 [Homo sapiens]
          Length = 387

 Score =  122 bits (305), Expect = 7e-28
 Identities = 77/279 (27%), Positives = 137/279 (49%), Gaps = 13/279 (4%)

Query: 53  LFVVGIAGNLLTMLVVSRFRELRTTTNLYLSSMAFSDLLIFLCMPLDLVRLWQYRPWNFG 112
           +F+VG  GN L + V+ R  +  +TTNL++ ++  +DL   LC       ++    W FG
Sbjct: 35  IFLVGTVGNTLVLAVLLRGGQAVSTTNLFILNLGVADLCFILCCVPFQATIYTLDGWVFG 94

Query: 113 DLLCKLFQFVSESCTYATVLTITALSVERYFAICFPLRAKVVVTKGRVKLVIFVIWAVAF 172
            LLCK   F+     +A+  T+ A+S++RY AI +PL ++ + T       I +IW ++ 
Sbjct: 95  SLLCKAVHFLIFLTMHASSFTLAAVSLDRYLAIRYPLHSRELRTPRNALAAIGLIWGLSL 154

Query: 173 CSAGPIFVLVGVEHENGTDPWDTNECRPTEFAVRSGLLTVMVWVSSIFFFLPVFCLTVLY 232
             +GP      + +   +   +   C P   A R   + +  +V S  + LPV  L + Y
Sbjct: 155 LFSGPY-----LSYYRQSQLANLTVCHPAWSAPRRRAMDICTFVFS--YLLPVLVLGLTY 207

Query: 233 SLIGRKLWRRRRGDAVVGASLRDQNHKQTVKMLAVVVFAFILCWLPFHVGRYLFSKSFEP 292
           +   R LW  R  D V   S   +  ++  +M+ +V   F LCW+P H    +    F  
Sbjct: 208 ARTLRYLW--RAVDPVAAGSGARRAKRKVTRMILIVAALFCLCWMPHHA--LILCVWF-- 261

Query: 293 GSLEIAQISQYCNLVSFVLFYLSAAINPILYNIMSKKYR 331
           G   + + +    ++S ++ Y ++ +NPI+Y ++SK +R
Sbjct: 262 GQFPLTRATYALRILSHLVSYANSCVNPIVYALVSKHFR 300


>gi|4557859 somatostatin receptor 2 [Homo sapiens]
          Length = 369

 Score =  117 bits (293), Expect = 2e-26
 Identities = 71/282 (25%), Positives = 138/282 (48%), Gaps = 21/282 (7%)

Query: 55  VVGIAGNLLTMLVVSRFRELRTTTNLYLSSMAFSDLLIFLCMPLDLVRLWQYRPWNFGDL 114
           ++G+ GN L + V+ R+ +++T TN+Y+ ++A +D L  L +P   +++     W FG  
Sbjct: 55  IIGLCGNTLVIYVILRYAKMKTITNIYILNLAIADELFMLGLPFLAMQVALVH-WPFGKA 113

Query: 115 LCKLFQFVSESCTYATVLTITALSVERYFAICFPLRAKVVVTKGRVKLVIFVIWAVAFCS 174
           +C++   V     + ++  +T +S++RY A+  P+++         K++   +W V+   
Sbjct: 114 ICRVVMTVDGINQFTSIFCLTVMSIDRYLAVVHPIKSAKWRRPRTAKMITMAVWGVSLLV 173

Query: 175 AGPIFVLVGVEHENGTDPWDTNECR---PTEFAVRSGLLTVMVWVSSIFFFLPVFCLTVL 231
             PI +  G+     ++ W  + C    P E         +  ++      L + CL  L
Sbjct: 174 ILPIMIYAGLR----SNQWGRSSCTINWPGESGAWYTGFIIYTFILGFLVPLTIICLCYL 229

Query: 232 YSLIGRKLWRRRRGDAVVGASLRDQNHKQTVKMLAVVVFAFILCWLPFHVGRYLFSKSFE 291
           + +I     + +     VG+S R ++ K+  +M+++VV  FI CWLPF    Y+F+ S  
Sbjct: 230 FIII-----KVKSSGIRVGSSKRKKSEKKVTRMVSIVVAVFIFCWLPF----YIFNVS-- 278

Query: 292 PGSLEIAQISQYCNLVSF--VLFYLSAAINPILYNIMSKKYR 331
             S+ I+       +  F  VL Y ++  NPILY  +S  ++
Sbjct: 279 SVSMAISPTPALKGMFDFVVVLTYANSCANPILYAFLSDNFK 320


>gi|4557865 somatostatin receptor 5 [Homo sapiens]
          Length = 364

 Score =  116 bits (290), Expect = 4e-26
 Identities = 94/327 (28%), Positives = 156/327 (47%), Gaps = 28/327 (8%)

Query: 21  WDAS-PGNDSLG-DELLQLFPAPLLAGVTATCVALFVV-----GIAGNLLTMLVVSRFRE 73
           W+AS PG  S G D    + PAP  AG  A  V +  +     G+ GN L + VV RF +
Sbjct: 12  WNASSPGAASGGGDNRTLVGPAPS-AGARAVLVPVLYLLVCAAGLGGNTLVIYVVLRFAK 70

Query: 74  LRTTTNLYLSSMAFSDLLIFLCMPLDLVRLWQYRPWNFGDLLCKLFQFVSESCTYATVLT 133
           ++T TN+Y+ ++A +D+L  L +P  L        W FG +LC+L   +     + +V  
Sbjct: 71  MKTVTNIYILNLAVADVLYMLGLPF-LATQNAASFWPFGPVLCRLVMTLDGVNQFTSVFC 129

Query: 134 ITALSVERYFAICFPLRAKVVVTKGRVKLVIFVIWAVAFCSAGPIFVLVGVEHENGTDPW 193
           +T +SV+RY A+  PL +         KL     W ++ C + P+ V   V+ E GT   
Sbjct: 130 LTVMSVDRYLAVVHPLSSARWRRPRVAKLASAAAWVLSLCMSLPLLVFADVQ-EGGT--- 185

Query: 194 DTNECRPTEFAVRSGLLTVMVWVSSIFFFLPVFCLTVLYSLIGRKLWRRRRGDAVVGASL 253
             N   P    +   +   +++ + + FF P+  + + Y LI  K+    R   V    +
Sbjct: 186 -CNASWPEPVGLWGAVF--IIYTAVLGFFAPLLVICLCYLLIVVKV----RAAGVRVGCV 238

Query: 254 RDQNHKQTVKMLAVVVFAFILCWLPFHVGRYLFSKSFEPGSLEIAQISQYCNLVSFV--L 311
           R ++ ++  +M+ VVV  F  CWLPF      F+ +    ++ + Q      L  FV  L
Sbjct: 239 RRRSERKVTRMVLVVVLVFAGCWLPF------FTVNIVNLAVALPQEPASAGLYFFVVIL 292

Query: 312 FYLSAAINPILYNIMSKKYRVAVFRLL 338
            Y ++  NP+LY  +S  +R +  ++L
Sbjct: 293 SYANSCANPVLYGFLSDNFRQSFQKVL 319


>gi|4557857 somatostatin receptor 1 [Homo sapiens]
          Length = 391

 Score =  114 bits (285), Expect = 1e-25
 Identities = 79/285 (27%), Positives = 143/285 (50%), Gaps = 17/285 (5%)

Query: 55  VVGIAGNLLTMLVVSRFRELRTTTNLYLSSMAFSDLLIFLCMPLDLVRLWQYRPWNFGDL 114
           +VG+ GN + + V+ R+ +++T TN+Y+ ++A +D L+ L +P  LV     R W FG L
Sbjct: 70  LVGLCGNSMVIYVILRYAKMKTATNIYILNLAIADELLMLSVPF-LVTSTLLRHWPFGAL 128

Query: 115 LCKLFQFVSESCTYATVLTITALSVERYFAICFPLRAKVVVTKGRVKLVIFVIWAVAFCS 174
           LC+L   V     + ++  +T LSV+RY A+  P++A         K+V   +W ++   
Sbjct: 129 LCRLVLSVDAVNMFTSIYCLTVLSVDRYVAVVHPIKAARYRRPTVAKVVNLGVWVLSLLV 188

Query: 175 AGPIFVLV-GVEHENGTDPWDTNECRPTEFAVRSGLLTVMVWVSSIFFFLPVFCLTVLYS 233
             PI V      + +GT   +     P +      L+  +++   + F LPV  + + Y 
Sbjct: 189 ILPIVVFSRTAANSDGTVACNMLMPEPAQ----RWLVGFVLYTFLMGFLLPVGAICLCYV 244

Query: 234 LIGRKLWRRRRGDAVVGASLRDQNHKQTVKMLAVVVFAFILCWLPFHVGRYLFSKSFEPG 293
           LI  K+   R      G   R ++ ++   M+ +VV  F++CW+PF+V + L +   E  
Sbjct: 245 LIIAKM---RMVALKAGWQQRKRSERKITLMVMMVVMVFVICWMPFYVVQ-LVNVFAEQD 300

Query: 294 SLEIAQISQYCNLVSFVLFYLSAAINPILYNIMSKKYRVAVFRLL 338
              ++Q+       S +L Y ++  NPILY  +S  ++ +  R+L
Sbjct: 301 DATVSQL-------SVILGYANSCANPILYGFLSDNFKRSFQRIL 338


>gi|4503465 endothelin receptor type A [Homo sapiens]
          Length = 427

 Score =  113 bits (282), Expect = 3e-25
 Identities = 76/296 (25%), Positives = 141/296 (47%), Gaps = 13/296 (4%)

Query: 47  TATCVALFVVGIAGNLLTMLVVSRFRELRTTTNLYLSSMAFSDLL-IFLCMPLDLVRL-- 103
           T     +F+VG+ GN   + ++ + + +R   N  ++S+A  DL+ + + +P+++ +L  
Sbjct: 84  TVISCTIFIVGMVGNATLLRIIYQNKCMRNGPNALIASLALGDLIYVVIDLPINVFKLLA 143

Query: 104 --WQYRPWNFGDLLCKLFQFVSESCTYATVLTITALSVERYFAICFPLRAKVVVTKGRVK 161
             W +   +FG  LCKLF F+ +S    TVL + ALSV+RY A+    R + +       
Sbjct: 144 GRWPFDHNDFGVFLCKLFPFLQKSSVGITVLNLCALSVDRYRAVASWSRVQGIGIPLVTA 203

Query: 162 LVIFVIWAVAFCSAGPI---FVLVGVEHENGTDPWDTNECRPTEFAVRSGLLTVMVWVSS 218
           + I  IW ++F  A P    FV+V  E+    +   T     T   +         W+  
Sbjct: 204 IEIVSIWILSFILAIPEAIGFVMVPFEYRG--EQHKTCMLNATSKFMEFYQDVKDWWLFG 261

Query: 219 IFFFLPVFCLTVLYSLIGRKLWRRRRGDAVVGASLRDQNHKQTVKMLAVVVFAFILCWLP 278
            +F +P+ C  + Y+L+  ++  RR G   +  S   +  ++  K +  +V  F LCW P
Sbjct: 262 FYFCMPLVCTAIFYTLMTCEMLNRRNGSLRIALSEHLKQRREVAKTVFCLVVIFALCWFP 321

Query: 279 FHVGRYLFSKSFEPGSLEIAQISQYCNLVSFV---LFYLSAAINPILYNIMSKKYR 331
            H+ R L    +        ++  +  L+ ++   L  +++ INPI    +SKK++
Sbjct: 322 LHLSRILKKTVYNEMDKNRCELLSFLLLMDYIGINLATMNSCINPIALYFVSKKFK 377


>gi|157426873 tachykinin receptor 2 [Homo sapiens]
          Length = 398

 Score =  113 bits (282), Expect = 3e-25
 Identities = 88/305 (28%), Positives = 142/305 (46%), Gaps = 19/305 (6%)

Query: 39  PAPLLAGVTATCVALFVVGIAGNLLTMLVVSRFRELRTTTNLYLSSMAFSDLLIFLCMPL 98
           P+  LA      +AL +V + GN + + ++   R +RT TN ++ ++A +DL +      
Sbjct: 29  PSWQLALWATAYLALVLVAVTGNAIVIWIILAHRRMRTVTNYFIVNLALADLCMAAFNAA 88

Query: 99  DLVRLWQYRPWNFGDLLCKLFQFVSESCTYATVLTITALSVERYFAICFPLRAKVVVTKG 158
                  +  W FG   C        +  + ++ ++TA++ +RY AI  P + +  ++  
Sbjct: 89  FNFVYASHNIWYFGRAFCYFQNLFPITAMFVSIYSMTAIAADRYMAIVHPFQPR--LSAP 146

Query: 159 RVKLVIFVIWAVAFCSAGPIFVLVGVEHENGTD----PWDTNECRPTEFAVRSGLLTVMV 214
             K VI  IW VA   A P      V  + G       W  +    T       LL   +
Sbjct: 147 STKAVIAGIWLVALALASPQCFYSTVTMDQGATKCVVAWPEDSGGKT-------LLLYHL 199

Query: 215 WVSSIFFFLPVFCLTVLYSLIGRKLWRRR-RGDAVVGASLRD-QNHKQTVKMLAVVVFAF 272
            V ++ +FLP+  + V YS+IG  LWRR   G    GA+LR  Q  K+ VK + +VV  F
Sbjct: 200 VVIALIYFLPLAVMFVAYSVIGLTLWRRAVPGHQAHGANLRHLQAMKKFVKTMVLVVLTF 259

Query: 273 ILCWLPFHVGRYLFSKSFEPGSLEIAQISQYCNLVSFVLFYLSAAINPILYNIMSKKYRV 332
            +CWLP+H+  Y    SF+   +   +  Q   L  F L   S   NPI+Y  ++ ++R 
Sbjct: 260 AICWLPYHL--YFILGSFQE-DIYCHKFIQQVYLALFWLAMSSTMYNPIIYCCLNHRFR- 315

Query: 333 AVFRL 337
           + FRL
Sbjct: 316 SGFRL 320


>gi|223718066 opioid receptor, mu 1 isoform MOR-1G2 [Homo sapiens]
          Length = 319

 Score =  109 bits (272), Expect = 4e-24
 Identities = 65/263 (24%), Positives = 129/263 (49%), Gaps = 12/263 (4%)

Query: 69  SRFRELRTTTNLYLSSMAFSDLLIFLCMPLDLVRLWQYRPWNFGDLLCKLFQFVSESCTY 128
           SR+ +++T TN+Y+ ++A +D L    +P   V  +    W FG +LCK+   +     +
Sbjct: 15  SRYTKMKTATNIYIFNLALADALATSTLPFQSVN-YLMGTWPFGTILCKIVISIDYYNMF 73

Query: 129 ATVLTITALSVERYFAICFPLRAKVVVTKGRVKLVIFVIWAVAFCSAGPIFVLVGVEHEN 188
            ++ T+  +SV+RY A+C P++A    T    K++    W ++     P+  +   ++  
Sbjct: 74  TSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKIINVCNWILSSAIGLPVMFMATTKYRQ 133

Query: 189 GTDPWDTNECRPTEFAVRSGLLTVMVWVSSIFFFLPVFCLTVLYSLIGRKLWRRRRGDAV 248
           G+         PT +     LL + V++ +  F +PV  +TV Y L+   + R +    +
Sbjct: 134 GSIDCTLTFSHPTWY--WENLLKICVFIFA--FIMPVLIITVCYGLM---ILRLKSVRML 186

Query: 249 VGASLRDQNHKQTVKMLAVVVFAFILCWLPFHVGRYLFSKSFEPGSLEIAQISQYCNLVS 308
            G+  +D+N ++  +M+ VVV  FI+CW P H+   + +    P +        +C    
Sbjct: 187 SGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHIYVIIKALVTIPETTFQTVSWHFC---- 242

Query: 309 FVLFYLSAAINPILYNIMSKKYR 331
             L Y ++ +NP+LY  + + ++
Sbjct: 243 IALGYTNSCLNPVLYAFLDENFK 265


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.328    0.140    0.444 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 12,854,439
Number of Sequences: 37866
Number of extensions: 517816
Number of successful extensions: 3287
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 477
Number of HSP's successfully gapped in prelim test: 261
Number of HSP's that attempted gapping in prelim test: 1573
Number of HSP's gapped (non-prelim): 1068
length of query: 366
length of database: 18,247,518
effective HSP length: 104
effective length of query: 262
effective length of database: 14,309,454
effective search space: 3749076948
effective search space used: 3749076948
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.8 bits)
S2: 62 (28.5 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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