Guide to the Human Genome
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Search of human proteins with 32967305

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|32967305 coenzyme Q6 homolog isoform a [Homo sapiens]
         (468 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|32967305 coenzyme Q6 homolog isoform a [Homo sapiens]              937   0.0  
gi|32967307 coenzyme Q6 homolog isoform b [Homo sapiens]              697   0.0  
gi|187960045 kynurenine 3-monooxygenase [Homo sapiens]                 35   0.19 
gi|223029410 talin 1 [Homo sapiens]                                    33   0.42 
gi|217272839 choline dehydrogenase [Homo sapiens]                      33   0.55 
gi|221307568 DENN/MADD domain containing 4A isoform 1 [Homo sapi...    32   1.6  
gi|221307566 DENN/MADD domain containing 4A isoform 2 [Homo sapi...    32   1.6  
gi|194306651 pyruvate dehydrogenase phosphatase regulatory subun...    32   1.6  
gi|58331161 PHD finger protein 19 isoform a [Homo sapiens]             31   2.8  
gi|194018472 serine (or cysteine) proteinase inhibitor, clade A ...    30   4.7  
gi|62865635 squalene epoxidase [Homo sapiens]                          30   6.1  
gi|34335251 disks large-associated protein 4 isoform b [Homo sap...    29   8.0  
gi|34335253 disks large-associated protein 4 isoform a [Homo sap...    29   8.0  
gi|13376331 L-2-hydroxyglutarate dehydrogenase precursor [Homo s...    29   8.0  
gi|149192845 ubiquitin specific protease 24 [Homo sapiens]             29   8.0  

>gi|32967305 coenzyme Q6 homolog isoform a [Homo sapiens]
          Length = 468

 Score =  937 bits (2421), Expect = 0.0
 Identities = 468/468 (100%), Positives = 468/468 (100%)

Query: 1   MAARLVSRCGAVRAAPHSGPLVSWRRWSGASTDTVYDVVVSGGGLVGAAMACALGYDIHF 60
           MAARLVSRCGAVRAAPHSGPLVSWRRWSGASTDTVYDVVVSGGGLVGAAMACALGYDIHF
Sbjct: 1   MAARLVSRCGAVRAAPHSGPLVSWRRWSGASTDTVYDVVVSGGGLVGAAMACALGYDIHF 60

Query: 61  HDKKILLLEAGPKKVLEKLSETYSNRVSSISPGSATLLSSFGAWDHICNMRYRAFRRMQV 120
           HDKKILLLEAGPKKVLEKLSETYSNRVSSISPGSATLLSSFGAWDHICNMRYRAFRRMQV
Sbjct: 61  HDKKILLLEAGPKKVLEKLSETYSNRVSSISPGSATLLSSFGAWDHICNMRYRAFRRMQV 120

Query: 121 WDACSEALIMFDKDNLDDMGYIVENDVIMHALTKQLEAVSDRVTVLYRSKAIRYTWPCPF 180
           WDACSEALIMFDKDNLDDMGYIVENDVIMHALTKQLEAVSDRVTVLYRSKAIRYTWPCPF
Sbjct: 121 WDACSEALIMFDKDNLDDMGYIVENDVIMHALTKQLEAVSDRVTVLYRSKAIRYTWPCPF 180

Query: 181 PMADSSPWVHITLGDGSTFQTKLLIGADGHNSGVRQAVGIQNVSWNYDQSAVVATLHLSE 240
           PMADSSPWVHITLGDGSTFQTKLLIGADGHNSGVRQAVGIQNVSWNYDQSAVVATLHLSE
Sbjct: 181 PMADSSPWVHITLGDGSTFQTKLLIGADGHNSGVRQAVGIQNVSWNYDQSAVVATLHLSE 240

Query: 241 ATENNVAWQRFLPSGPIALLPLSDTLSSLVWSTSHEHAAELVSMDEEKFVDAVNSAFWSD 300
           ATENNVAWQRFLPSGPIALLPLSDTLSSLVWSTSHEHAAELVSMDEEKFVDAVNSAFWSD
Sbjct: 241 ATENNVAWQRFLPSGPIALLPLSDTLSSLVWSTSHEHAAELVSMDEEKFVDAVNSAFWSD 300

Query: 301 ADHTDFIDTAGAMLQYAVSLLKPTKVSARQLPPSVARVDAKSRVLFPLGLGHAAEYVRPR 360
           ADHTDFIDTAGAMLQYAVSLLKPTKVSARQLPPSVARVDAKSRVLFPLGLGHAAEYVRPR
Sbjct: 301 ADHTDFIDTAGAMLQYAVSLLKPTKVSARQLPPSVARVDAKSRVLFPLGLGHAAEYVRPR 360

Query: 361 VALIGDAAHRVHPLAGQGVNMGFGDISSLAHHLSTAAFNGKDLGSVSHLTGYETERQRHN 420
           VALIGDAAHRVHPLAGQGVNMGFGDISSLAHHLSTAAFNGKDLGSVSHLTGYETERQRHN
Sbjct: 361 VALIGDAAHRVHPLAGQGVNMGFGDISSLAHHLSTAAFNGKDLGSVSHLTGYETERQRHN 420

Query: 421 TALLAATDLLKRLYSTSASPLVLLRTWGLQATNAVSPLKEQIMAFASK 468
           TALLAATDLLKRLYSTSASPLVLLRTWGLQATNAVSPLKEQIMAFASK
Sbjct: 421 TALLAATDLLKRLYSTSASPLVLLRTWGLQATNAVSPLKEQIMAFASK 468


>gi|32967307 coenzyme Q6 homolog isoform b [Homo sapiens]
          Length = 393

 Score =  697 bits (1800), Expect = 0.0
 Identities = 349/349 (100%), Positives = 349/349 (100%)

Query: 120 VWDACSEALIMFDKDNLDDMGYIVENDVIMHALTKQLEAVSDRVTVLYRSKAIRYTWPCP 179
           VWDACSEALIMFDKDNLDDMGYIVENDVIMHALTKQLEAVSDRVTVLYRSKAIRYTWPCP
Sbjct: 45  VWDACSEALIMFDKDNLDDMGYIVENDVIMHALTKQLEAVSDRVTVLYRSKAIRYTWPCP 104

Query: 180 FPMADSSPWVHITLGDGSTFQTKLLIGADGHNSGVRQAVGIQNVSWNYDQSAVVATLHLS 239
           FPMADSSPWVHITLGDGSTFQTKLLIGADGHNSGVRQAVGIQNVSWNYDQSAVVATLHLS
Sbjct: 105 FPMADSSPWVHITLGDGSTFQTKLLIGADGHNSGVRQAVGIQNVSWNYDQSAVVATLHLS 164

Query: 240 EATENNVAWQRFLPSGPIALLPLSDTLSSLVWSTSHEHAAELVSMDEEKFVDAVNSAFWS 299
           EATENNVAWQRFLPSGPIALLPLSDTLSSLVWSTSHEHAAELVSMDEEKFVDAVNSAFWS
Sbjct: 165 EATENNVAWQRFLPSGPIALLPLSDTLSSLVWSTSHEHAAELVSMDEEKFVDAVNSAFWS 224

Query: 300 DADHTDFIDTAGAMLQYAVSLLKPTKVSARQLPPSVARVDAKSRVLFPLGLGHAAEYVRP 359
           DADHTDFIDTAGAMLQYAVSLLKPTKVSARQLPPSVARVDAKSRVLFPLGLGHAAEYVRP
Sbjct: 225 DADHTDFIDTAGAMLQYAVSLLKPTKVSARQLPPSVARVDAKSRVLFPLGLGHAAEYVRP 284

Query: 360 RVALIGDAAHRVHPLAGQGVNMGFGDISSLAHHLSTAAFNGKDLGSVSHLTGYETERQRH 419
           RVALIGDAAHRVHPLAGQGVNMGFGDISSLAHHLSTAAFNGKDLGSVSHLTGYETERQRH
Sbjct: 285 RVALIGDAAHRVHPLAGQGVNMGFGDISSLAHHLSTAAFNGKDLGSVSHLTGYETERQRH 344

Query: 420 NTALLAATDLLKRLYSTSASPLVLLRTWGLQATNAVSPLKEQIMAFASK 468
           NTALLAATDLLKRLYSTSASPLVLLRTWGLQATNAVSPLKEQIMAFASK
Sbjct: 345 NTALLAATDLLKRLYSTSASPLVLLRTWGLQATNAVSPLKEQIMAFASK 393


>gi|187960045 kynurenine 3-monooxygenase [Homo sapiens]
          Length = 486

 Score = 34.7 bits (78), Expect = 0.19
 Identities = 14/30 (46%), Positives = 19/30 (63%)

Query: 356 YVRPRVALIGDAAHRVHPLAGQGVNMGFGD 385
           + +    L+GDAAH + P  GQG+N GF D
Sbjct: 294 HFKSHCVLLGDAAHAIVPFFGQGMNAGFED 323


>gi|223029410 talin 1 [Homo sapiens]
          Length = 2541

 Score = 33.5 bits (75), Expect = 0.42
 Identities = 29/122 (23%), Positives = 50/122 (40%), Gaps = 6/122 (4%)

Query: 224  SWNYDQSAVVATLHLSEATENNV-----AWQRFLPSGPIALLPLSDTLSSLVWSTSHEHA 278
            S N+++  + A   ++ AT   V     A +  +  G +  +P ++ L    WS     A
Sbjct: 2338 SLNFEEQILEAAKSIAAATSALVKAASAAQRELVAQGKVGAIP-ANALDDGQWSQGLISA 2396

Query: 279  AELVSMDEEKFVDAVNSAFWSDADHTDFIDTAGAMLQYAVSLLKPTKVSARQLPPSVARV 338
            A +V+       +A N+A    A     I +A  +      LL   KV A Q   ++ R+
Sbjct: 2397 ARMVAAATNNLCEAANAAVQGHASQEKLISSAKQVAASTAQLLVACKVKADQDSEAMKRL 2456

Query: 339  DA 340
             A
Sbjct: 2457 QA 2458


>gi|217272839 choline dehydrogenase [Homo sapiens]
          Length = 594

 Score = 33.1 bits (74), Expect = 0.55
 Identities = 20/49 (40%), Positives = 27/49 (55%), Gaps = 3/49 (6%)

Query: 28 SGASTDTVYDVVVSGGGLVGAAMACALGYDIHFHDKKILLLEAGPKKVL 76
          +G+ +   Y  VV G G  G  +A  L  D     +++LLLEAGPK VL
Sbjct: 33 AGSESRDEYSYVVVGAGSAGCVLAGRLTED---PAERVLLLEAGPKDVL 78


>gi|221307568 DENN/MADD domain containing 4A isoform 1 [Homo
           sapiens]
          Length = 1906

 Score = 31.6 bits (70), Expect = 1.6
 Identities = 50/213 (23%), Positives = 82/213 (38%), Gaps = 40/213 (18%)

Query: 142 IVENDVIMHALTKQLEAVSDRVTVLYRSKAIRYTWPCPFPMADSSPWVHITLGDGSTFQT 201
           + E+ +++H+L     +V   VT    S    + WPCP+      P   + L D  +   
Sbjct: 413 VTEHKILIHSLRP---SVLTSVTEALVSMIFPFHWPCPY-----VPLCPLALADVLSAPC 464

Query: 202 KLLIGADGHNSGVRQAVGIQNVSWNYDQSAVVATLHLSEAT------ENNVAWQRFLPSG 255
             ++G D     +            YD    V+ + +   T      + NVAW + LP  
Sbjct: 465 PFIVGIDSRYFDL------------YDPPPDVSCVDVDTNTISQIGDKKNVAW-KILPKK 511

Query: 256 PIALLPLSDTLSSLVWSTSHEHAAELVS--MDEEKFVDAVNSAFWSDADHTDFID--TAG 311
           P     L +TL++L     H+  A+L     D+     A+N   ++       ID     
Sbjct: 512 PCK--NLMNTLNNL-----HQQLAKLQQRPRDDGLMDLAINDYDFNSGKRLHMIDLEIQE 564

Query: 312 AMLQYAVSLLKPTKVSARQL--PPSVARVDAKS 342
           A L +  S+LK  +   R +   PS    DA S
Sbjct: 565 AFLFFMASILKGYRSYLRPITQAPSETATDAAS 597


>gi|221307566 DENN/MADD domain containing 4A isoform 2 [Homo
           sapiens]
          Length = 1863

 Score = 31.6 bits (70), Expect = 1.6
 Identities = 50/213 (23%), Positives = 82/213 (38%), Gaps = 40/213 (18%)

Query: 142 IVENDVIMHALTKQLEAVSDRVTVLYRSKAIRYTWPCPFPMADSSPWVHITLGDGSTFQT 201
           + E+ +++H+L     +V   VT    S    + WPCP+      P   + L D  +   
Sbjct: 413 VTEHKILIHSLRP---SVLTSVTEALVSMIFPFHWPCPY-----VPLCPLALADVLSAPC 464

Query: 202 KLLIGADGHNSGVRQAVGIQNVSWNYDQSAVVATLHLSEAT------ENNVAWQRFLPSG 255
             ++G D     +            YD    V+ + +   T      + NVAW + LP  
Sbjct: 465 PFIVGIDSRYFDL------------YDPPPDVSCVDVDTNTISQIGDKKNVAW-KILPKK 511

Query: 256 PIALLPLSDTLSSLVWSTSHEHAAELVS--MDEEKFVDAVNSAFWSDADHTDFID--TAG 311
           P     L +TL++L     H+  A+L     D+     A+N   ++       ID     
Sbjct: 512 PCK--NLMNTLNNL-----HQQLAKLQQRPRDDGLMDLAINDYDFNSGKRLHMIDLEIQE 564

Query: 312 AMLQYAVSLLKPTKVSARQL--PPSVARVDAKS 342
           A L +  S+LK  +   R +   PS    DA S
Sbjct: 565 AFLFFMASILKGYRSYLRPITQAPSETATDAAS 597


>gi|194306651 pyruvate dehydrogenase phosphatase regulatory
          subunit [Homo sapiens]
          Length = 879

 Score = 31.6 bits (70), Expect = 1.6
 Identities = 27/83 (32%), Positives = 35/83 (42%), Gaps = 21/83 (25%)

Query: 1  MAARLVSRCGAVRAAPHSGPLVSWRRWSGASTDTVY------------DVVVSGGGLVGA 48
          M  RL+S  G  RA+P       W+ WS A   T               VV+ GGG+ G 
Sbjct: 2  MFYRLLSIVGRQRASP------GWQNWSSARNSTSAAEARSMALPTQAQVVICGGGITGT 55

Query: 49 AMACALGYDIHFHDKKILLLEAG 71
          ++A  L        K I+LLE G
Sbjct: 56 SVAYHLS---KMGWKDIVLLEQG 75


>gi|58331161 PHD finger protein 19 isoform a [Homo sapiens]
          Length = 580

 Score = 30.8 bits (68), Expect = 2.8
 Identities = 21/57 (36%), Positives = 34/57 (59%), Gaps = 7/57 (12%)

Query: 260 LPLSDTLSSLVWSTSHEHAAELV--SMDEEKFVDAVNSA--FWSDADHTDFIDTAGA 312
           +P SD  S+  WST+H H A +   ++DE + + + +S   F+SD D TD   T+G+
Sbjct: 404 IPSSDFTSA--WSTNH-HLASIFDFTLDEIQSLKSASSGQTFFSDVDSTDAASTSGS 457


>gi|194018472 serine (or cysteine) proteinase inhibitor, clade A
           (alpha-1 antiproteinase, antitrypsin), member 5 [Homo
           sapiens]
          Length = 406

 Score = 30.0 bits (66), Expect = 4.7
 Identities = 17/46 (36%), Positives = 27/46 (58%)

Query: 280 ELVSMDEEKFVDAVNSAFWSDADHTDFIDTAGAMLQYAVSLLKPTK 325
           +LV   ++ FV A+ + + +D   T+F D+AGAM Q    + K TK
Sbjct: 136 DLVVDLQDTFVSAMKTLYLADTFPTNFRDSAGAMKQINDYVAKQTK 181


>gi|62865635 squalene epoxidase [Homo sapiens]
          Length = 574

 Score = 29.6 bits (65), Expect = 6.1
 Identities = 13/26 (50%), Positives = 17/26 (65%)

Query: 361 VALIGDAAHRVHPLAGQGVNMGFGDI 386
           V L+GDA +  HPL G G+ + F DI
Sbjct: 403 VLLLGDAYNMRHPLTGGGMTVAFKDI 428


>gi|34335251 disks large-associated protein 4 isoform b [Homo
           sapiens]
          Length = 453

 Score = 29.3 bits (64), Expect = 8.0
 Identities = 27/109 (24%), Positives = 38/109 (34%), Gaps = 5/109 (4%)

Query: 171 AIRYTWPCPFPMADSSPWVHITLGDGSTFQTKLLIGADGHNSGVRQAVGIQNVSWNYDQS 230
           A + T P   P   S P++ +T+   +       + +  H S V    G+ N S + D S
Sbjct: 17  AYKKTPPPVPPRTTSKPFISVTVQSSTESAQDTYLDSQDHKSEVTSQSGLSNSSDSLDSS 76

Query: 231 AVVATLHLSEATENNVAWQRFLPSGPIALLPLSDTLSSLVWSTSHEHAA 279
                      T   VA     P  P     L     +L  S SH  AA
Sbjct: 77  T-----RPPSVTRGGVAPAPEAPEPPPKHAALKSEQGTLTSSESHPEAA 120


>gi|34335253 disks large-associated protein 4 isoform a [Homo
           sapiens]
          Length = 989

 Score = 29.3 bits (64), Expect = 8.0
 Identities = 27/109 (24%), Positives = 38/109 (34%), Gaps = 5/109 (4%)

Query: 171 AIRYTWPCPFPMADSSPWVHITLGDGSTFQTKLLIGADGHNSGVRQAVGIQNVSWNYDQS 230
           A + T P   P   S P++ +T+   +       + +  H S V    G+ N S + D S
Sbjct: 556 AYKKTPPPVPPRTTSKPFISVTVQSSTESAQDTYLDSQDHKSEVTSQSGLSNSSDSLDSS 615

Query: 231 AVVATLHLSEATENNVAWQRFLPSGPIALLPLSDTLSSLVWSTSHEHAA 279
                      T   VA     P  P     L     +L  S SH  AA
Sbjct: 616 T-----RPPSVTRGGVAPAPEAPEPPPKHAALKSEQGTLTSSESHPEAA 659


>gi|13376331 L-2-hydroxyglutarate dehydrogenase precursor [Homo
          sapiens]
          Length = 463

 Score = 29.3 bits (64), Expect = 8.0
 Identities = 18/46 (39%), Positives = 24/46 (52%), Gaps = 5/46 (10%)

Query: 9  CGAVRAAPHSGPLVSWRRWSGASTDTVYDVVVSGGGLVGAAMACAL 54
          CG     P   PL    R +  S+   +D+V+ GGG+VG A A AL
Sbjct: 27 CGFASGRPR--PLCGGSRSASTSS---FDIVIVGGGIVGLASARAL 67


>gi|149192845 ubiquitin specific protease 24 [Homo sapiens]
          Length = 2460

 Score = 29.3 bits (64), Expect = 8.0
 Identities = 24/86 (27%), Positives = 37/86 (43%), Gaps = 7/86 (8%)

Query: 204  LIGADGHNSGVRQAVGIQNVSW-NYDQSAVVATLHLSEATENNVAWQRFLPSGPIALLPL 262
            L+GA   N+ +R+    Q   + N   +  +  LH   +++ NVA   F    PI++ P 
Sbjct: 2156 LLGASRQNNQIRRWSSAQAREFGNLHNTVALLVLHSDVSSQRNVAPGIFKQRPPISIAPS 2215

Query: 263  SDTLSSLVWSTSHEHAAELVSMDEEK 288
            S  L        HE    L+ M E K
Sbjct: 2216 SPLL------PLHEEVEALLFMSEGK 2235


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.319    0.131    0.397 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 16,639,731
Number of Sequences: 37866
Number of extensions: 670095
Number of successful extensions: 1652
Number of sequences better than 10.0: 15
Number of HSP's better than 10.0 without gapping: 5
Number of HSP's successfully gapped in prelim test: 10
Number of HSP's that attempted gapping in prelim test: 1645
Number of HSP's gapped (non-prelim): 18
length of query: 468
length of database: 18,247,518
effective HSP length: 106
effective length of query: 362
effective length of database: 14,233,722
effective search space: 5152607364
effective search space used: 5152607364
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 64 (29.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
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