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Search of human proteins with 122937404
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|122937404 membrane bound O-acyltransferase domain containing
1 [Homo sapiens]
(495 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|122937404 membrane bound O-acyltransferase domain containing ... 1017 0.0
gi|40548387 O-acyltransferase (membrane bound) domain containing... 565 e-161
gi|42542394 lysophosphatidylcholine acyltransferase 3 [Homo sapi... 122 7e-28
gi|189571629 membrane bound O-acyltransferase domain containing ... 119 5e-27
gi|225703079 membrane bound O-acyltransferase domain containing ... 111 2e-24
gi|225703081 membrane bound O-acyltransferase domain containing ... 101 1e-21
gi|225703033 membrane bound O-acyltransferase domain containing ... 101 1e-21
gi|225703037 membrane bound O-acyltransferase domain containing ... 62 1e-09
gi|45439331 porcupine isoform B [Homo sapiens] 60 3e-09
gi|45439333 porcupine isoform C [Homo sapiens] 59 1e-08
gi|45439329 porcupine isoform A [Homo sapiens] 56 7e-08
gi|45439335 porcupine isoform D [Homo sapiens] 55 1e-07
gi|45439337 porcupine isoform E [Homo sapiens] 50 6e-06
gi|54112390 calcium channel, voltage-dependent, alpha 2/delta su... 32 1.3
gi|31083344 chemokine orphan receptor 1 [Homo sapiens] 30 5.0
gi|224465209 phosphoseryl-tRNA kinase [Homo sapiens] 30 6.6
gi|54291714 olfactory receptor, family 6, subfamily B, member 2 ... 30 6.6
gi|116256333 membrane metallo-endopeptidase [Homo sapiens] 29 8.6
gi|116256331 membrane metallo-endopeptidase [Homo sapiens] 29 8.6
gi|116256327 membrane metallo-endopeptidase [Homo sapiens] 29 8.6
gi|116256329 membrane metallo-endopeptidase [Homo sapiens] 29 8.6
gi|17402886 HEAT-like repeat-containing protein isoform 1 [Homo ... 29 8.6
>gi|122937404 membrane bound O-acyltransferase domain containing 1
[Homo sapiens]
Length = 495
Score = 1017 bits (2629), Expect = 0.0
Identities = 495/495 (100%), Positives = 495/495 (100%)
Query: 1 MAAEPQPSSLSYRTTGSTYLHPLSELLGIPLDQVNFVVCQLVALFAAFWFRIYLRPGTTS 60
MAAEPQPSSLSYRTTGSTYLHPLSELLGIPLDQVNFVVCQLVALFAAFWFRIYLRPGTTS
Sbjct: 1 MAAEPQPSSLSYRTTGSTYLHPLSELLGIPLDQVNFVVCQLVALFAAFWFRIYLRPGTTS 60
Query: 61 SDVRHAVATIFGIYFVIFCFGWYSVHLFVLVLMCYAIMVTASVSNIHRYSFFVAMGYLTI 120
SDVRHAVATIFGIYFVIFCFGWYSVHLFVLVLMCYAIMVTASVSNIHRYSFFVAMGYLTI
Sbjct: 61 SDVRHAVATIFGIYFVIFCFGWYSVHLFVLVLMCYAIMVTASVSNIHRYSFFVAMGYLTI 120
Query: 121 CHISRIYIFHYGILTTDFSGPLMIVTQKITTLAFQVHDGLGRRAEDLSAEQHRLAIKVKP 180
CHISRIYIFHYGILTTDFSGPLMIVTQKITTLAFQVHDGLGRRAEDLSAEQHRLAIKVKP
Sbjct: 121 CHISRIYIFHYGILTTDFSGPLMIVTQKITTLAFQVHDGLGRRAEDLSAEQHRLAIKVKP 180
Query: 181 SFLEYLSYLLNFMSVIAGPCNNFKDYIAFIEGKHIHMKLLEVNWKRKGFHSLPEPSPTGA 240
SFLEYLSYLLNFMSVIAGPCNNFKDYIAFIEGKHIHMKLLEVNWKRKGFHSLPEPSPTGA
Sbjct: 181 SFLEYLSYLLNFMSVIAGPCNNFKDYIAFIEGKHIHMKLLEVNWKRKGFHSLPEPSPTGA 240
Query: 241 VIHKLGITLVSLLLFLTLTKTFPVTCLVDDWFVHKASFPARLCYLYVVMQASKPKYYFAW 300
VIHKLGITLVSLLLFLTLTKTFPVTCLVDDWFVHKASFPARLCYLYVVMQASKPKYYFAW
Sbjct: 241 VIHKLGITLVSLLLFLTLTKTFPVTCLVDDWFVHKASFPARLCYLYVVMQASKPKYYFAW 300
Query: 301 TLADAVNNAAGFGFSGVDKNGNFCWDLLSNLNIWKIETATSFKMYLENWNIQTATWLKCV 360
TLADAVNNAAGFGFSGVDKNGNFCWDLLSNLNIWKIETATSFKMYLENWNIQTATWLKCV
Sbjct: 301 TLADAVNNAAGFGFSGVDKNGNFCWDLLSNLNIWKIETATSFKMYLENWNIQTATWLKCV 360
Query: 361 CYQRVPWYPTVLTFILSALWHGVYPGYYFTFLTGILVTLAARAVRNNYRHYFLSSRALKA 420
CYQRVPWYPTVLTFILSALWHGVYPGYYFTFLTGILVTLAARAVRNNYRHYFLSSRALKA
Sbjct: 361 CYQRVPWYPTVLTFILSALWHGVYPGYYFTFLTGILVTLAARAVRNNYRHYFLSSRALKA 420
Query: 421 VYDAGTWAVTQLAVSYTVAPFVMLAVEPTISLYKSMYFYLHIISLLIILFLPMKPQAHTQ 480
VYDAGTWAVTQLAVSYTVAPFVMLAVEPTISLYKSMYFYLHIISLLIILFLPMKPQAHTQ
Sbjct: 421 VYDAGTWAVTQLAVSYTVAPFVMLAVEPTISLYKSMYFYLHIISLLIILFLPMKPQAHTQ 480
Query: 481 RRPQTLNSINKRKTD 495
RRPQTLNSINKRKTD
Sbjct: 481 RRPQTLNSINKRKTD 495
>gi|40548387 O-acyltransferase (membrane bound) domain containing 2
[Homo sapiens]
Length = 520
Score = 565 bits (1456), Expect = e-161
Identities = 265/476 (55%), Positives = 348/476 (73%), Gaps = 3/476 (0%)
Query: 14 TTGSTYLHPLSELLGIPLDQVNFVVCQLVALFAAFWFRIYLRPGTTSSDVRHAVATIFGI 73
TTGST L PLS + +P+DQVNFVVCQL AL AA WFR YL TSS +RH VAT+ G+
Sbjct: 6 TTGSTLLQPLSNAVQLPIDQVNFVVCQLFALLAAIWFRTYLHSSKTSSFIRHVVATLLGL 65
Query: 74 YFVIFCFGWYSVHLFVLVLMCYAIMVTASVSNIHRYSFFVAMGYLTICHISRIYIFHYGI 133
Y +FCFGWY++H V + Y IM+ V N+H Y F A+GYLT+C ++R+YIF YG
Sbjct: 66 YLALFCFGWYALHFLVQSGISYCIMIIIGVENMHNYCFVFALGYLTVCQVTRVYIFDYGQ 125
Query: 134 LTTDFSGPLMIVTQKITTLAFQVHDGLGRRAEDLSAEQHRLAIKVKPSFLEYLSYLLNFM 193
+ DFSGP+MI+TQKIT+LA ++HDG+ R+ E+L++ Q LA++ PS LEYLSY NFM
Sbjct: 126 YSADFSGPMMIITQKITSLACEIHDGMFRKDEELTSSQRDLAVRRMPSLLEYLSYNCNFM 185
Query: 194 SVIAGPCNNFKDYIAFIEGKHIHMKLLEVNWKRKGFHSLPEPSPTGAVIHKLGITLVSLL 253
++AGP ++KDYI FIEG+ H+ N K + + EPSP AV+ KL + +SLL
Sbjct: 186 GILAGPLCSYKDYITFIEGRSYHITQSGENGKEETQYERTEPSPNTAVVQKLLVCGLSLL 245
Query: 254 LFLTLTKTFPVTCLVDDWFVHKASFPARLCYLYVVMQASKPKYYFAWTLADAVNNAAGFG 313
LT+ T PV +D+ F AS+P ++ YLY+ + A++PKYYFAWTLADA+NNAAGFG
Sbjct: 246 FHLTICTTLPVEYNIDEHFQATASWPTKIIYLYISLLAARPKYYFAWTLADAINNAAGFG 305
Query: 314 FSGVDKNGNFCWDLLSNLNIWKIETATSFKMYLENWNIQTATWLKCVCYQRVPWYPTVLT 373
F G D+NG WDL+SNL I +IE +TSFKM+L+NWNIQTA WLK VCY+R + PT+ T
Sbjct: 306 FRGYDENGAARWDLISNLRIQQIEMSTSFKMFLDNWNIQTALWLKRVCYERTSFSPTIQT 365
Query: 374 FILSALWHGVYPGYYFTFLTGILVTLAARAVRNNYRHYFLSSRALKAVYDAGTWAVTQLA 433
FILSA+WHGVYPGYY TFLTG+L+TLAARA+RNN+RHYF+ LK YD TW VTQ+A
Sbjct: 366 FILSAIWHGVYPGYYLTFLTGVLMTLAARAMRNNFRHYFIEPSQLKLFYDVITWIVTQVA 425
Query: 434 VSYTVAPFVMLAVEPTISLYKSMYFYLHIISLLIILFLPMKPQAHTQRRPQTLNSI 489
+SYTV PFV+L+++P+++ Y S Y+ LHI+ +L++L LP+K TQRR T +I
Sbjct: 426 ISYTVVPFVLLSIKPSLTFYSSWYYCLHILGILVLLLLPVK---KTQRRKNTHENI 478
>gi|42542394 lysophosphatidylcholine acyltransferase 3 [Homo
sapiens]
Length = 487
Score = 122 bits (306), Expect = 7e-28
Identities = 115/482 (23%), Positives = 204/482 (42%), Gaps = 48/482 (9%)
Query: 20 LHPLSELLGIPLDQVNFVVCQLVALFAAFWFRIYLRPGTTSSDVRHAVATIFGIYFVIFC 79
L+ L+ LG + ++ + A ++R YL T + H T G+ F
Sbjct: 28 LNKLATSLGASEQALRLIISIFLGYPFALFYRHYLFYKETY--LIHLFHTFTGLSIAYFN 85
Query: 80 FGWYSVHLFVLVLMCYAIM------VTASVSNIHRYSFFVAMGYLTICHISRIYIFHYGI 133
FG H + +++ + I+ +TA ++ +F M YL ++ Y G
Sbjct: 86 FGNQLYHSLLCIVLQFLILRLMGRTITAVLT-----TFCFQMAYL----LAGYYYTATGN 136
Query: 134 LTTDFSGPLMIVTQKITTLAFQVHDGLGRRAEDLSAEQHRLAIKVKPSFLEYLSYLLNFM 193
++ P ++T K+ LA DG G+ LS+EQ + AI+ PS LE + +
Sbjct: 137 YDIKWTMPHCVLTLKLIGLAVDYFDG-GKDQNSLSSEQQKYAIRGVPSLLEVAGFSYFYG 195
Query: 194 SVIAGPCNNFKDYIAFIEGKHIHMKLLEVNWKRKGFHSLPEPSPTGAV--IHKLGITLVS 251
+ + GP + Y+ ++G+ I +P P + + +L + L
Sbjct: 196 AFLVGPQFSMNHYMKLVQGELI---------------DIPGKIPNSIIPALKRLSLGLFY 240
Query: 252 LLLFLTLTKTFPVTCLV-DDWFVHKASFPARLCYLYVVMQASKPKYYFAWTLADAVNNAA 310
L+ + L+ L+ +D+ H F R Y+ + + KY W + + V
Sbjct: 241 LVGYTLLSPHITEDYLLTEDYDNHPFWF--RCMYMLIWGKFVLYKYVTCWLVTEGVCILT 298
Query: 311 GFGFSGVDKNGNFCWDLLSNLNIWKIETATSFKMYLENWNIQTATWLKCVCYQRVPWYPT 370
G GF+G ++ G WD +N+ +W ET F + ++NI T W+ ++R+ +
Sbjct: 299 GLGFNGFEEKGKAKWDACANMKVWLFETNPRFTGTIASFNINTNAWVARYIFKRLKFLGN 358
Query: 371 V-----LTFILSALWHGVYPGYYFTFLTGILVTLAAR-AVRNNYRHYFLSSRALKAVYDA 424
L+ + ALWHG++ GY F L+ + R A R LS A V
Sbjct: 359 KELSQGLSLLFLALWHGLHSGYLVCFQMEFLIVIVERQAARLIQESPTLSKLAAITVLQP 418
Query: 425 GTWAVTQ----LAVSYTVAPFVMLAVEPTISLYKSMYFYLHIISLLIILFLPMKPQAHTQ 480
+ V Q L + Y++ F + + + +YKS+YF HI L ++ LP +A
Sbjct: 419 FYYLVQQTIHWLFMGYSMTAFCLFTWDKWLKVYKSIYFLGHIFFLSLLFILPYIHKAMVP 478
Query: 481 RR 482
R+
Sbjct: 479 RK 480
>gi|189571629 membrane bound O-acyltransferase domain containing 4
[Homo sapiens]
Length = 435
Score = 119 bits (299), Expect = 5e-27
Identities = 102/429 (23%), Positives = 192/429 (44%), Gaps = 57/429 (13%)
Query: 60 SSDVRHAVATIFGIYFVIFCFGWYSVHLFVLVLMCYAIMVTASVSNIHRYSFFVAMGYLT 119
S+ R+ G + G Y+V +F + A++ + + +HR++F M + T
Sbjct: 36 STRARYLFLLTGGGALAVAAMGSYAVLVFTPAVCAVALLCSLAPQQVHRWTFCFQMSWQT 95
Query: 120 ICHISRIYIFHY-----GILTTDFSGPLMIVTQKITTLAFQVHDGLGRRAEDLSAEQHRL 174
+CH+ Y +Y + LM++TQ++T+L+ + +G + A + L
Sbjct: 96 LCHLGLHYTEYYLHEPPSVRFCITLSSLMLLTQRVTSLSLDICEGKVKAASGGFRSRSSL 155
Query: 175 AIKVKPSFLEYLSYLLNFMSVIAGPCNNFKDYIAFIEGK---HIHMKLLEVNWKRKGFHS 231
+ V + L Y SYLL F +++ G +F+ + A ++G H ++W+
Sbjct: 156 SEHVCKA-LPYFSYLLFFPALLGGSLCSFQRFQARVQGSSALHPRHSFWALSWR------ 208
Query: 232 LPEPSPTGAVIHKLGITLVSL-LLFLTLTKTFPVTCLVDDWFVHKASFPARLCYLYVVMQ 290
G+ ++ L L + +++ + D + +YVV
Sbjct: 209 --------------GLQILGLECLNVAVSRVVDAGAGLTDCQQFEC--------IYVVWT 246
Query: 291 AS---KPKYYFAWTLADAVNNAAGFGFSGVDKNGNFCWDLLSNLNIWKIETATSFKMYLE 347
+ K YY W L D++ +AAGFG G + + + +IW +E ++
Sbjct: 247 TAGLFKLTYYSHWILDDSLLHAAGFGPELGQSPGEEGY--VPDADIWTLERTHRISVFSR 304
Query: 348 NWNIQTATWLKCVCYQRVPWYPTVLTFILSALWHGVYPGYYFTFLTGILVTLAARAVRNN 407
WN TA WL+ + +Q +P + TF SA WHG++PG F F+ ++ A + ++
Sbjct: 305 KWNQSTARWLRRLVFQHSRAWPLLQTFAFSAWWHGLHPGQVFGFVCWAVMVEADYLI-HS 363
Query: 408 YRHYFLSSRALKAVYDAGTWAVTQLAVSYTVAPFVMLAVEP--------TISLYKSMYFY 459
+ + F+ S ++ Y TWA TQL ++Y +MLAVE + Y S++
Sbjct: 364 FANEFIRSWPMRLFYRTLTWAHTQLIIAY-----IMLAVEVRSLSSLWLLCNSYNSVFPM 418
Query: 460 LHIISLLII 468
++ I LL++
Sbjct: 419 VYCILLLLL 427
>gi|225703079 membrane bound O-acyltransferase domain containing 7
isoform 1 [Homo sapiens]
Length = 472
Score = 111 bits (277), Expect = 2e-24
Identities = 108/431 (25%), Positives = 187/431 (43%), Gaps = 59/431 (13%)
Query: 68 ATIFGIYFVIFCFGWYSVHLFVLVLMCYAIMVTASVSNIHRYSFFVAMGYLTICHISRIY 127
A G+ +F G +++H V +L +A+ + A + H + YL +
Sbjct: 34 AAAVGLGLTLFTCGPHTLHSLVTILGTWAL-IQAQPCSCHALALAWTFSYLLFFRALSLL 92
Query: 128 IFHYGILT-TDFSGPL-MIVTQKITTLAFQVHD-GLGRRAEDLSAEQHRLAIKVKP---S 181
G+ T T F+ + +++T K+ +LA +V D L +R E S + + P S
Sbjct: 93 ----GLPTPTPFTNAVQLLLTLKLVSLASEVQDLHLAQRKEMASGFSKGPTLGLLPDVPS 148
Query: 182 FLEYLSYLLNFMSVIAGPCNNFKDYIAFIEGKHIHMKLLEVNWKRKGFH-SLPEPSPTGA 240
+E LSY ++ ++ GP ++ Y+ +W + F ++P P
Sbjct: 149 LMETLSYSYCYVGIMTGPFFRYRTYL---------------DWLEQPFPGAVPSLRP--- 190
Query: 241 VIHKLGITLVSLLLFLTLTKTFPVTCLVDDWFVHKASFPARLCYLYVVMQASKPKYYFAW 300
++ + + LLFL + FP+ + +D F + PARL Y+ V A + ++Y AW
Sbjct: 191 LLRRAWPAPLFGLLFLLSSHLFPLEAVREDAF-YARPLPARLFYMIPVFFAFRMRFYVAW 249
Query: 301 TLADAVNNAAGFGFSGVDKNGN----------------------FCWDLLSNLNIWKIET 338
A+ AAGFG V + ++ + N++ + +
Sbjct: 250 IAAECGCIAAGFGAYPVAAKARAGGGPTLQCPPPSSPEKAASLEYDYETIRNIDCYSTDF 309
Query: 339 ATSFKMYLENWNIQTATWLKCVCYQRVPWYPTVL----TFILSALWHGVYPGYYFTFLTG 394
+ + WN+ WL Y+ P VL T +LSA WHG++PGYY +FLT
Sbjct: 310 CVRVRDGMRYWNMTVQWWLAQYIYKSAPARSYVLRSAWTMLLSAYWHGLHPGYYLSFLT- 368
Query: 395 ILVTLAARAVRNNYRHYFLSSRALKAVYDAGTWAVTQLAVSYTVAPFVMLAVEPTISLYK 454
I + LAA + LS KA +D W + A Y FV+L++ T+ +
Sbjct: 369 IPLCLAAEGRLESALRGRLSPGGQKA-WDWVHWFLKMRAYDYMCMGFVLLSLADTLRYWA 427
Query: 455 SMYFYLHIISL 465
S+YF +H ++L
Sbjct: 428 SIYFCIHFLAL 438
>gi|225703081 membrane bound O-acyltransferase domain containing 7
isoform 2 [Homo sapiens]
Length = 399
Score = 101 bits (252), Expect = 1e-21
Identities = 94/358 (26%), Positives = 156/358 (43%), Gaps = 57/358 (15%)
Query: 139 SGPLMIVTQKITTLAFQVHD-GLGRRAEDLSAEQHRLAIKVKP---SFLEYLSYLLNFMS 194
SGP ++V+ LA +V D L +R E S + + P S +E LSY ++
Sbjct: 34 SGPALLVS-----LASEVQDLHLAQRKEMASGFSKGPTLGLLPDVPSLMETLSYSYCYVG 88
Query: 195 VIAGPCNNFKDYIAFIEGKHIHMKLLEVNWKRKGFH-SLPEPSPTGAVIHKLGITLVSLL 253
++ GP ++ Y+ +W + F ++P P ++ + + L
Sbjct: 89 IMTGPFFRYRTYL---------------DWLEQPFPGAVPSLRP---LLRRAWPAPLFGL 130
Query: 254 LFLTLTKTFPVTCLVDDWFVHKASFPARLCYLYVVMQASKPKYYFAWTLADAVNNAAGFG 313
LFL + FP+ + +D F + PARL Y+ V A + ++Y AW A+ AAGFG
Sbjct: 131 LFLLSSHLFPLEAVREDAF-YARPLPARLFYMIPVFFAFRMRFYVAWIAAECGCIAAGFG 189
Query: 314 FSGVDKNGN----------------------FCWDLLSNLNIWKIETATSFKMYLENWNI 351
V + ++ + N++ + + + + WN+
Sbjct: 190 AYPVAAKARAGGGPTLQCPPPSSPEKAASLEYDYETIRNIDCYSTDFCVRVRDGMRYWNM 249
Query: 352 QTATWLKCVCYQRVPWYPTVL----TFILSALWHGVYPGYYFTFLTGILVTLAARAVRNN 407
WL Y+ P VL T +LSA WHG++PGYY +FLT I + LAA +
Sbjct: 250 TVQWWLAQYIYKSAPARSYVLRSAWTMLLSAYWHGLHPGYYLSFLT-IPLCLAAEGRLES 308
Query: 408 YRHYFLSSRALKAVYDAGTWAVTQLAVSYTVAPFVMLAVEPTISLYKSMYFYLHIISL 465
LS KA +D W + A Y FV+L++ T+ + S+YF +H ++L
Sbjct: 309 ALRGRLSPGGQKA-WDWVHWFLKMRAYDYMCMGFVLLSLADTLRYWASIYFCIHFLAL 365
>gi|225703033 membrane bound O-acyltransferase domain containing 7
isoform 2 [Homo sapiens]
Length = 399
Score = 101 bits (252), Expect = 1e-21
Identities = 94/358 (26%), Positives = 156/358 (43%), Gaps = 57/358 (15%)
Query: 139 SGPLMIVTQKITTLAFQVHD-GLGRRAEDLSAEQHRLAIKVKP---SFLEYLSYLLNFMS 194
SGP ++V+ LA +V D L +R E S + + P S +E LSY ++
Sbjct: 34 SGPALLVS-----LASEVQDLHLAQRKEMASGFSKGPTLGLLPDVPSLMETLSYSYCYVG 88
Query: 195 VIAGPCNNFKDYIAFIEGKHIHMKLLEVNWKRKGFH-SLPEPSPTGAVIHKLGITLVSLL 253
++ GP ++ Y+ +W + F ++P P ++ + + L
Sbjct: 89 IMTGPFFRYRTYL---------------DWLEQPFPGAVPSLRP---LLRRAWPAPLFGL 130
Query: 254 LFLTLTKTFPVTCLVDDWFVHKASFPARLCYLYVVMQASKPKYYFAWTLADAVNNAAGFG 313
LFL + FP+ + +D F + PARL Y+ V A + ++Y AW A+ AAGFG
Sbjct: 131 LFLLSSHLFPLEAVREDAF-YARPLPARLFYMIPVFFAFRMRFYVAWIAAECGCIAAGFG 189
Query: 314 FSGVDKNGN----------------------FCWDLLSNLNIWKIETATSFKMYLENWNI 351
V + ++ + N++ + + + + WN+
Sbjct: 190 AYPVAAKARAGGGPTLQCPPPSSPEKAASLEYDYETIRNIDCYSTDFCVRVRDGMRYWNM 249
Query: 352 QTATWLKCVCYQRVPWYPTVL----TFILSALWHGVYPGYYFTFLTGILVTLAARAVRNN 407
WL Y+ P VL T +LSA WHG++PGYY +FLT I + LAA +
Sbjct: 250 TVQWWLAQYIYKSAPARSYVLRSAWTMLLSAYWHGLHPGYYLSFLT-IPLCLAAEGRLES 308
Query: 408 YRHYFLSSRALKAVYDAGTWAVTQLAVSYTVAPFVMLAVEPTISLYKSMYFYLHIISL 465
LS KA +D W + A Y FV+L++ T+ + S+YF +H ++L
Sbjct: 309 ALRGRLSPGGQKA-WDWVHWFLKMRAYDYMCMGFVLLSLADTLRYWASIYFCIHFLAL 365
>gi|225703037 membrane bound O-acyltransferase domain containing 7
isoform 3 [Homo sapiens]
Length = 344
Score = 62.0 bits (149), Expect = 1e-09
Identities = 71/328 (21%), Positives = 133/328 (40%), Gaps = 53/328 (16%)
Query: 68 ATIFGIYFVIFCFGWYSVHLFVLVLMCYAIMVTASVSNIHRYSFFVAMGYLTICHISRIY 127
A G+ +F G +++H V +L +A+ + A + H + YL +
Sbjct: 34 AAAVGLGLTLFTCGPHTLHSLVTILGTWAL-IQAQPCSCHALALAWTFSYLLFFRALSLL 92
Query: 128 IFHYGILT-TDFSGPL-MIVTQKITTLAFQVHD-GLGRRAEDLSAEQHRLAIKVKP---S 181
G+ T T F+ + +++T K+ +LA +V D L +R E S + + P S
Sbjct: 93 ----GLPTPTPFTNAVQLLLTLKLVSLASEVQDLHLAQRKEMASGFSKGPTLGLLPDVPS 148
Query: 182 FLEYLSYLLNFMSVIAGPCNNFKDYIAFIEGKHIHMKLLEVNWKRKGFH-SLPEPSPTGA 240
+E LSY ++ ++ GP ++ Y+ +W + F ++P P
Sbjct: 149 LMETLSYSYCYVGIMTGPFFRYRTYL---------------DWLEQPFPGAVPSLRP--- 190
Query: 241 VIHKLGITLVSLLLFLTLTKTFPVTCLVDDWFVHKASFPARLCYLYVVMQASKPKYYFAW 300
++ + + LLFL + FP+ + +D F + PARL Y+ V A + ++Y AW
Sbjct: 191 LLRRAWPAPLFGLLFLLSSHLFPLEAVREDAF-YARPLPARLFYMIPVFFAFRMRFYVAW 249
Query: 301 TLADAVNNAAGFGFSGVDKNG----------------------NFCWDLLSNLNIWKIET 338
A+ AAGFG V + ++ + N++ + +
Sbjct: 250 IAAECGCIAAGFGAYPVAAKARAGGGPTLQCPPPSSPEKAASLEYDYETIRNIDCYSTDF 309
Query: 339 ATSFKMYLENWNIQTATWLKCVCYQRVP 366
+ + WN+ WL Y+ P
Sbjct: 310 CVRVRDGMRYWNMTVQWWLAQYIYKSAP 337
>gi|45439331 porcupine isoform B [Homo sapiens]
Length = 456
Score = 60.5 bits (145), Expect = 3e-09
Identities = 80/347 (23%), Positives = 142/347 (40%), Gaps = 52/347 (14%)
Query: 61 SDVRHAVATIFGIYFVIFCFGWYSVHLFVLVLMCYAIMVTASVSNIHRYSFFVAMGYLTI 120
S ++HA G + + F + V + +L L+CY ++ S+ HR F+++ L
Sbjct: 49 SYLKHASTVAGGFFSLYHFFQLHMVWVVLLSLLCYLVLFLCRHSS-HR-GVFLSVTILIY 106
Query: 121 CHISRIYIFHYGILTTDFSGPLMIVTQKITTLAFQVHDGLGRRAEDLSAEQHRLAIKVKP 180
+ +++ + G MIV K +L F + G + P
Sbjct: 107 LLMGEMHMVDT-VTWHKMRGAQMIVAMKAVSLGFDLDRG---------------EVGTVP 150
Query: 181 SFLEYLSYLLNFMSVIAGPCNNFKDYIAFIEGKHIHMKLLEVNWKRKGFHSLPEPSPTGA 240
S +E++ YL +++ GP +F Y+ ++G+ L W +K
Sbjct: 151 SPVEFMGYLYFVGTIVFGPWISFHSYLQAVQGRP-----LSCRWLQK------------- 192
Query: 241 VIHKLGITLVSLLLFLTL-TKTFPVTC-LVDDWFVHKASFPARLCYLYVVMQASKPKYYF 298
V L + L+ L+L + FP L D + AR Y + YF
Sbjct: 193 VARSLALALLCLVLSTCVGPYLFPYFIPLNGDRLLRNKKRKARWLRAYESAVSFHFSNYF 252
Query: 299 AWTLADAVNNAAGFGFSGVDKNGNFCWDLLSNLNIWKIETATSFKMYLENWNIQTATWLK 358
L++A AG GF+ ++ + WDL + + +E S + +WN+ + WL
Sbjct: 253 VGFLSEATATLAGAGFT--EEKDHLEWDLTVSKPL-NVELPRSMVEVVTSWNLPMSYWLN 309
Query: 359 CVCYQ---RVPWYPTVL-TFILSALWHGVYPGYYFTF-LTGILVTLA 400
++ R+ + VL T+ SAL HG F+F L +L++LA
Sbjct: 310 NYVFKNALRLGTFSAVLVTYAASALLHG------FSFHLAAVLLSLA 350
>gi|45439333 porcupine isoform C [Homo sapiens]
Length = 455
Score = 58.5 bits (140), Expect = 1e-08
Identities = 77/346 (22%), Positives = 142/346 (41%), Gaps = 51/346 (14%)
Query: 61 SDVRHAVATIFGIYFVIFCFGWYSVHLFVLVLMCYAIMVTASVSNIHRYSFFVAMGYLTI 120
S ++HA G + + F + V + +L L+CY ++ S+ HR F+++ L
Sbjct: 49 SYLKHASTVAGGFFSLYHFFQLHMVWVVLLSLLCYLVLFLCRHSS-HR-GVFLSVTILIY 106
Query: 121 CHISRIYIFHYGILTTDFSGPLMIVTQKITTLAFQVHDGLGRRAEDLSAEQHRLAIKVKP 180
+ +++ + G MIV K +L F + G + P
Sbjct: 107 LLMGEMHMVDT-VTWHKMRGAQMIVAMKAVSLGFDLDRG---------------EVGTVP 150
Query: 181 SFLEYLSYLLNFMSVIAGPCNNFKDYIAFIEGKHIHMKLLEVNWKRKGFHSLPEPSPTGA 240
S +E++ YL +++ GP +F Y+ ++G+ L W +K
Sbjct: 151 SPVEFMGYLYFVGTIVFGPWISFHSYLQAVQGRP-----LSCRWLQK------------- 192
Query: 241 VIHKLGITLVSLLLFLTL-TKTFPVTCLVDDWFVHKASFPARLCYLYVVMQASKPKYYFA 299
V L + L+ L+L + FP ++ + + R Y + YF
Sbjct: 193 VARSLALALLCLVLSTCVGPYLFPYFIPLNGDRLLRKGTMVRWLRAYESAVSFHFSNYFV 252
Query: 300 WTLADAVNNAAGFGFSGVDKNGNFCWDLLSNLNIWKIETATSFKMYLENWNIQTATWLKC 359
L++A AG GF+ ++ + WDL + + +E S + +WN+ + WL
Sbjct: 253 GFLSEATATLAGAGFT--EEKDHLEWDLTVSKPL-NVELPRSMVEVVTSWNLPMSYWLNN 309
Query: 360 VCYQ---RVPWYPTVL-TFILSALWHGVYPGYYFTF-LTGILVTLA 400
++ R+ + VL T+ SAL HG F+F L +L++LA
Sbjct: 310 YVFKNALRLGTFSAVLVTYAASALLHG------FSFHLAAVLLSLA 349
>gi|45439329 porcupine isoform A [Homo sapiens]
Length = 450
Score = 56.2 bits (134), Expect = 7e-08
Identities = 79/350 (22%), Positives = 143/350 (40%), Gaps = 64/350 (18%)
Query: 61 SDVRHAVATIFGIYFVIFCFGWYSVHLFVLVLMCYAIMVTASVSNIHRYSFFVAMGYLTI 120
S ++HA G + + F + V + +L L+CY ++ S+ HR F+++ L
Sbjct: 49 SYLKHASTVAGGFFSLYHFFQLHMVWVVLLSLLCYLVLFLCRHSS-HR-GVFLSVTILIY 106
Query: 121 CHISRIYIFHYGILTTDFSGPLMIVTQKITTLAFQVHDGLGRRAEDLSAEQHRLAIKVKP 180
+ +++ + G MIV K +L F + G + P
Sbjct: 107 LLMGEMHMVDT-VTWHKMRGAQMIVAMKAVSLGFDLDRG---------------EVGTVP 150
Query: 181 SFLEYLSYLLNFMSVIAGPCNNFKDYIAFIEGKHIHMKLLEVNWKRKGFHSLPEPSPTGA 240
S +E++ YL +++ GP +F Y+ ++G+ L W +K
Sbjct: 151 SPVEFMGYLYFVGTIVFGPWISFHSYLQAVQGRP-----LSCRWLQK------------- 192
Query: 241 VIHKLGITLVSLLLFLTLTKTFPVTCLVDDWFVHKASFPA-RLCYLYVVMQASKPKY--- 296
V L + L+ L+L TC+ F + RL ++ S +
Sbjct: 193 VARSLALALLCLVL---------STCVGPYLFPYFIPLNGDRLLRKWLRAYESAVSFHFS 243
Query: 297 -YFAWTLADAVNNAAGFGFSGVDKNGNFCWDLLSNLNIWKIETATSFKMYLENWNIQTAT 355
YF L++A AG GF+ ++ + WDL + + +E S + +WN+ +
Sbjct: 244 NYFVGFLSEATATLAGAGFT--EEKDHLEWDLTVSKPL-NVELPRSMVEVVTSWNLPMSY 300
Query: 356 WLKCVCYQ---RVPWYPTVL-TFILSALWHGVYPGYYFTF-LTGILVTLA 400
WL ++ R+ + VL T+ SAL HG F+F L +L++LA
Sbjct: 301 WLNNYVFKNALRLGTFSAVLVTYAASALLHG------FSFHLAAVLLSLA 344
>gi|45439335 porcupine isoform D [Homo sapiens]
Length = 461
Score = 55.1 bits (131), Expect = 1e-07
Identities = 81/352 (23%), Positives = 145/352 (41%), Gaps = 57/352 (16%)
Query: 61 SDVRHAVATIFGIYFVIFCFGWYSVHLFVLVLMCYAIMVTASVSNIHRYSFFVAMGYLTI 120
S ++HA G + + F + V + +L L+CY ++ S+ HR F+++ L
Sbjct: 49 SYLKHASTVAGGFFSLYHFFQLHMVWVVLLSLLCYLVLFLCRHSS-HR-GVFLSVTILIY 106
Query: 121 CHISRIYIFHYGILTTDFSGPLMIVTQKITTLAFQVHDGLGRRAEDLSAEQHRLAIKVKP 180
+ +++ + G MIV K +L F + G + P
Sbjct: 107 LLMGEMHMVDT-VTWHKMRGAQMIVAMKAVSLGFDLDRG---------------EVGTVP 150
Query: 181 SFLEYLSYLLNFMSVIAGPCNNFKDYIAFIEGKHIHMKLLEVNWKRKGFHSLPEPSPTGA 240
S +E++ YL +++ GP +F Y+ ++G+ L W +K
Sbjct: 151 SPVEFMGYLYFVGTIVFGPWISFHSYLQAVQGRP-----LSCRWLQK------------- 192
Query: 241 VIHKLGITLVSLLLFLTL-TKTFPVTC-LVDDWFVHKASFPAR---LCYLYVVMQASKPK 295
V L + L+ L+L + FP L D + AR + +L A
Sbjct: 193 VARSLALALLCLVLSTCVGPYLFPYFIPLNGDRLLRNKKRKARGTMVRWLRAYESAVSFH 252
Query: 296 Y--YFAWTLADAVNNAAGFGFSGVDKNGNFCWDLLSNLNIWKIETATSFKMYLENWNIQT 353
+ YF L++A AG GF+ ++ + WDL + + +E S + +WN+
Sbjct: 253 FSNYFVGFLSEATATLAGAGFT--EEKDHLEWDLTVSKPL-NVELPRSMVEVVTSWNLPM 309
Query: 354 ATWLKCVCYQ---RVPWYPTVL-TFILSALWHGVYPGYYFTF-LTGILVTLA 400
+ WL ++ R+ + VL T+ SAL HG F+F L +L++LA
Sbjct: 310 SYWLNNYVFKNALRLGTFSAVLVTYAASALLHG------FSFHLAAVLLSLA 355
>gi|45439337 porcupine isoform E [Homo sapiens]
Length = 379
Score = 49.7 bits (117), Expect = 6e-06
Identities = 74/326 (22%), Positives = 133/326 (40%), Gaps = 64/326 (19%)
Query: 85 VHLFVLVLMCYAIMVTASVSNIHRYSFFVAMGYLTICHISRIYIFHYGILTTDFSGPLMI 144
V + +L L+CY ++ S+ HR F+++ L + +++ + G MI
Sbjct: 2 VWVVLLSLLCYLVLFLCRHSS-HR-GVFLSVTILIYLLMGEMHMVDT-VTWHKMRGAQMI 58
Query: 145 VTQKITTLAFQVHDGLGRRAEDLSAEQHRLAIKVKPSFLEYLSYLLNFMSVIAGPCNNFK 204
V K +L F + G + PS +E++ YL +++ GP +F
Sbjct: 59 VAMKAVSLGFDLDRG---------------EVGTVPSPVEFMGYLYFVGTIVFGPWISFH 103
Query: 205 DYIAFIEGKHIHMKLLEVNWKRKGFHSLPEPSPTGAVIHKLGITLVSLLLFLTLTKTFPV 264
Y+ ++G+ L W +K V L + L+ L+L
Sbjct: 104 SYLQAVQGRP-----LSCRWLQK-------------VARSLALALLCLVL---------S 136
Query: 265 TCLVDDWFVHKASFPA-RLCYLYVVMQASKPKY----YFAWTLADAVNNAAGFGFSGVDK 319
TC+ F + RL ++ S + YF L++A AG GF+ ++
Sbjct: 137 TCVGPYLFPYFIPLNGDRLLRKWLRAYESAVSFHFSNYFVGFLSEATATLAGAGFT--EE 194
Query: 320 NGNFCWDLLSNLNIWKIETATSFKMYLENWNIQTATWLKCVCYQ---RVPWYPTVL-TFI 375
+ WDL + + +E S + +WN+ + WL ++ R+ + VL T+
Sbjct: 195 KDHLEWDLTVSKPL-NVELPRSMVEVVTSWNLPMSYWLNNYVFKNALRLGTFSAVLVTYA 253
Query: 376 LSALWHGVYPGYYFTF-LTGILVTLA 400
SAL HG F+F L +L++LA
Sbjct: 254 ASALLHG------FSFHLAAVLLSLA 273
>gi|54112390 calcium channel, voltage-dependent, alpha 2/delta
subunit 1 [Homo sapiens]
Length = 1091
Score = 32.0 bits (71), Expect = 1.3
Identities = 23/71 (32%), Positives = 34/71 (47%), Gaps = 8/71 (11%)
Query: 267 LVDDWFVHKASFPARL----CYLYVVMQASKPKYYFAWTLADAVNNAAGFGFSGVDKNGN 322
L DD FV+ ASF + C+ ++V + K L DAVNN G + K +
Sbjct: 283 LSDDDFVNVASFNSNAQDVSCFQHLVQANVRNKK----VLKDAVNNITAKGITDYKKGFS 338
Query: 323 FCWDLLSNLNI 333
F ++ L N N+
Sbjct: 339 FAFEQLLNYNV 349
>gi|31083344 chemokine orphan receptor 1 [Homo sapiens]
Length = 362
Score = 30.0 bits (66), Expect = 5.0
Identities = 19/72 (26%), Positives = 32/72 (44%), Gaps = 1/72 (1%)
Query: 21 HPLSE-LLGIPLDQVNFVVCQLVALFAAFWFRIYLRPGTTSSDVRHAVATIFGIYFVIFC 79
H + E L+G+ L V ++ A F+F + +S +H+ I Y V+F
Sbjct: 203 HSIKEWLIGMELVSVVLGFAVPFSIIAVFYFLLARAISASSDQEKHSSRKIIFSYVVVFL 262
Query: 80 FGWYSVHLFVLV 91
W H+ VL+
Sbjct: 263 VCWLPYHVAVLL 274
>gi|224465209 phosphoseryl-tRNA kinase [Homo sapiens]
Length = 348
Score = 29.6 bits (65), Expect = 6.6
Identities = 12/33 (36%), Positives = 18/33 (54%)
Query: 264 VTCLVDDWFVHKASFPARLCYLYVVMQASKPKY 296
+TCL D + A+F A+ CYL S+P +
Sbjct: 115 ITCLKDQDLIFSAAFEAQSCYLLTKTAVSRPLF 147
>gi|54291714 olfactory receptor, family 6, subfamily B, member 2
[Homo sapiens]
Length = 312
Score = 29.6 bits (65), Expect = 6.6
Identities = 18/57 (31%), Positives = 33/57 (57%), Gaps = 3/57 (5%)
Query: 72 GIYFVIFCFGWYSVHLFVLVLMCYAIMVTASVSNIHR--YSFFVAMGYLTICHISRI 126
G+ +++F + +LFVLV I++ S +++HR Y F +M +L I ++S I
Sbjct: 22 GLQYLLFLL-FLLTYLFVLVENLAIILIVWSSTSLHRPMYYFLSSMSFLEIWYVSDI 77
>gi|116256333 membrane metallo-endopeptidase [Homo sapiens]
Length = 750
Score = 29.3 bits (64), Expect = 8.6
Identities = 14/40 (35%), Positives = 22/40 (55%)
Query: 323 FCWDLLSNLNIWKIETATSFKMYLENWNIQTATWLKCVCY 362
F DL+S+L+ E+ +F+ L +TATW +C Y
Sbjct: 375 FIMDLVSSLSRTYKESRNAFRKALYGTTSETATWRRCANY 414
>gi|116256331 membrane metallo-endopeptidase [Homo sapiens]
Length = 750
Score = 29.3 bits (64), Expect = 8.6
Identities = 14/40 (35%), Positives = 22/40 (55%)
Query: 323 FCWDLLSNLNIWKIETATSFKMYLENWNIQTATWLKCVCY 362
F DL+S+L+ E+ +F+ L +TATW +C Y
Sbjct: 375 FIMDLVSSLSRTYKESRNAFRKALYGTTSETATWRRCANY 414
>gi|116256327 membrane metallo-endopeptidase [Homo sapiens]
Length = 750
Score = 29.3 bits (64), Expect = 8.6
Identities = 14/40 (35%), Positives = 22/40 (55%)
Query: 323 FCWDLLSNLNIWKIETATSFKMYLENWNIQTATWLKCVCY 362
F DL+S+L+ E+ +F+ L +TATW +C Y
Sbjct: 375 FIMDLVSSLSRTYKESRNAFRKALYGTTSETATWRRCANY 414
>gi|116256329 membrane metallo-endopeptidase [Homo sapiens]
Length = 750
Score = 29.3 bits (64), Expect = 8.6
Identities = 14/40 (35%), Positives = 22/40 (55%)
Query: 323 FCWDLLSNLNIWKIETATSFKMYLENWNIQTATWLKCVCY 362
F DL+S+L+ E+ +F+ L +TATW +C Y
Sbjct: 375 FIMDLVSSLSRTYKESRNAFRKALYGTTSETATWRRCANY 414
>gi|17402886 HEAT-like repeat-containing protein isoform 1 [Homo
sapiens]
Length = 873
Score = 29.3 bits (64), Expect = 8.6
Identities = 24/98 (24%), Positives = 39/98 (39%), Gaps = 16/98 (16%)
Query: 122 HISRIYIFHYGILTTDFSGPLMIVTQKITTLAFQVHDGLGRRAEDLSAEQHRLAIKVKPS 181
H+ ++ YGI T D + +K+ TL Q +G ++ P
Sbjct: 316 HLGKLCHGLYGIFTPDQHLRFLEFYKKLCTLGLQQENGHNEN-------------QIPPQ 362
Query: 182 FLEYLSYLLNFMSVIAGPCNNFKDYIAFIEGKHIHMKL 219
LE ++SV NF I F++ K+ HM+L
Sbjct: 363 ILEQEK---KYISVRKNCAYNFPAMIVFVDPKNFHMEL 397
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.329 0.140 0.450
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 17,819,962
Number of Sequences: 37866
Number of extensions: 727589
Number of successful extensions: 2038
Number of sequences better than 10.0: 22
Number of HSP's better than 10.0 without gapping: 19
Number of HSP's successfully gapped in prelim test: 3
Number of HSP's that attempted gapping in prelim test: 1986
Number of HSP's gapped (non-prelim): 30
length of query: 495
length of database: 18,247,518
effective HSP length: 106
effective length of query: 389
effective length of database: 14,233,722
effective search space: 5536917858
effective search space used: 5536917858
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.8 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.